POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_B_TC9B1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4a5w	COMPLEMENT C5 (Homo sapiens)	5 / 11	SER A 114 THR A  53 SER A  68 SER A  55 SER A  65	None	1.33A	9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1deu	PROCATHEPSIN X (Homo sapiens)	4 / 7	TRP A 202 TYR A 169 GLU A 208 TYR A 164	None	1.29A	24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1ef7	CATHEPSIN X (Homo sapiens)	4 / 7	TRP A 202 TYR A 169 GLU A 208 TYR A 164	None	1.28A	21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3tsw	TIGHT JUNCTION PROTEIN ZO-1 (Homo sapiens)	4 / 7	TYR A 633 TRP A 557 GLU A 530 TYR A 527	None	1.31A	20.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XYT_D_TC9D1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4hqp	ALPHA7 NICOTINIC RECEPTOR CHIMERA (Homo sapiens; Lymnaea stagnalis)	4 / 7	TYR A  91 TRP A 145 TYR A 184 TYR A 191	None	0.60A	36.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XYT_D_TC9D1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zjs	ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA,SOLUBLE ACETYLCHOLINE RECEPTOR,ACETYLCHOLI NE RECEPTOR SUBUNIT ALPHA,SOLUBLE ACETYLCHOLINE RECEPTOR (Aplysia californica; Homo sapiens)	5 / 7	TYR A  93 TRP A 147 TYR A 188 GLU A 193 TYR A 195	None	0.71A	78.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1lt8	BETAINE-HOMOCYSTEINE METHYLTRANSFERASE (Homo sapiens)	4 / 8	TYR A 284 ILE A 281 ASP A 220 SER A 224	None None CIT  A 701 (-2.8A) None	1.11A	19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1sl5	MDC-SIGN1B TYPE I ISOFORM (Homo sapiens)	4 / 8	THR A 261 TYR A 268 ARG A 312 ILE A 376	None	0.94A	20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1sl6	C-TYPE LECTIN DC-SIGNR (Homo sapiens)	4 / 8	THR A 273 TYR A 280 ARG A 324 ILE A 388	None	0.89A	19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1um1	KIAA1849 PROTEIN (Homo sapiens)	4 / 8	TYR A  39 GLN A  41 ILE A 103 ASP A  27	None	1.05A	18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1v5w	MEIOTIC RECOMBINATION PROTEIN DMC1/LIM15 HOMOLOG (Homo sapiens)	4 / 8	THR A 267 GLN A 269 ASP A 223 SER A 136	None	1.09A	20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	2it6	CD209 ANTIGEN (Homo sapiens)	4 / 8	THR A 261 TYR A 268 ARG A 312 ILE A 376	None	0.90A	20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	2uyy	N-PAC PROTEIN (Homo sapiens)	4 / 8	THR A 327 TYR A 357 ARG A 352 ILE A 351	None	1.03A	20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3hhr	HUMAN GROWTH HORMONE (Homo sapiens)	4 / 8	GLN A 122 MET A 125 ILE A 121 SER A  85	None	1.06A	19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3nvq	SEMAPHORIN-7A (Homo sapiens)	4 / 8	TYR A 408 GLN A 304 ARG A 245 ASP A 432	None None None NDG  A   4 (-3.9A)	1.13A	17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3pbl	D(3) DOPAMINE RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.07A	18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3qak	ADENOSINE RECEPTOR A2A,LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.07A	17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3rwr	DNA REPAIR PROTEIN XRCC4 (Homo sapiens)	4 / 8	THR A  37 GLN A  21 ARG A   3 ILE A   5	None	0.85A	20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3u7u	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	4 / 8	THR A 151 ARG A 171 ILE A 141 SER A 148	None	1.02A	16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3vw7	PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.07A	17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4bkg	SMALL UBIQUITIN-RELATED MODIFIER 2 (Homo sapiens)	4 / 8	GLN A  88 ILE A  58 ASP A  26 SER A  28	None	1.01A	19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4ig9	NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1 (Homo sapiens)	4 / 8	GLN A 352 ILE A 356 ASP A 348 SER A 265	None	1.08A	22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4lde	LYSOZYME, BETA-2 ADRENERGIC RECEPTOR (Escherichia virus T4; Homo sapiens)	4 / 8	THR A 899 TYR A 890 ILE A 882 SER A 901	None	1.13A	20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4wn5	HYPOXIA-INDUCIBLE FACTOR 3-ALPHA (Homo sapiens)	4 / 8	TYR A 275 ARG A 305 ILE A 278 ASP A 284	None	1.00A	19.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zjs	ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA,SOLUBLE ACETYLCHOLINE RECEPTOR,ACETYLCHOLI NE RECEPTOR SUBUNIT ALPHA,SOLUBLE ACETYLCHOLINE RECEPTOR (Aplysia californica; Homo sapiens)	7 / 8	THR A  36 GLN A  57 ARG A  59 MET A 116 ILE A 118 ASP A 164 SER A 167	None	0.56A	78.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zwj	CHIMERA PROTEIN OF HUMAN RHODOPSIN, MOUSE S-ARRESTIN, AND T4 ENDOLYSIN (Escherichia virus T4; Homo sapiens; Mus musculus)	4 / 8	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.09A	13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zzh	NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1 (Homo sapiens)	4 / 8	GLN A 352 ILE A 356 ASP A 348 SER A 265	None	1.02A	22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5eut	PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA,ENDOLYSIN,PH OSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1036 TYR A1027 ILE A1019 SER A1038	None	1.12A	18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5iaa	UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 5 (Homo sapiens)	4 / 8	GLN A 217 MET A 297 ASP C  80 SER A 213	None	1.12A	19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5v88	LYSOZYME,DCN1-LIKE PROTEIN 1 (Escherichia virus T4; Homo sapiens)	4 / 8	THR A  34 TYR A  25 ILE A  17 SER A  36	None	1.05A	19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5zbq	NEUROPEPTIDE Y RECEPTOR TYPE 1,T4 LYSOZYME (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1033 TYR A1024 ILE A1016 SER A1035	None	1.04A	17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	6d1w	POLYCYSTIN-2 (Homo sapiens)	4 / 8	THR A 260 GLN A 255 ARG A 251 SER A 286	None	0.92A	17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	6ffh	METABOTROPIC GLUTAMATE RECEPTOR 5,ENDOLYSIN (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.07A	17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	2m9a	E3 UBIQUITIN-PROTEIN LIGASE ZFP91 (Homo sapiens)	4 / 7	TYR A  18 CYH A  19 CYH A  16 GLU A  17	None ZN  A 101 (-2.3A) ZN  A 101 (-2.3A) None	1.25A	17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3tsw	TIGHT JUNCTION PROTEIN ZO-1 (Homo sapiens)	4 / 7	TYR A 633 TRP A 557 GLU A 530 TYR A 527	None	1.28A	20.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XYT_G_TC9G1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4hqp	ALPHA7 NICOTINIC RECEPTOR CHIMERA (Homo sapiens; Lymnaea stagnalis)	4 / 7	TYR A  91 TRP A 145 TYR A 184 TYR A 191	None	0.57A	36.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XYT_G_TC9G1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zjs	ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA,SOLUBLE ACETYLCHOLINE RECEPTOR,ACETYLCHOLI NE RECEPTOR SUBUNIT ALPHA,SOLUBLE ACETYLCHOLINE RECEPTOR (Aplysia californica; Homo sapiens)	5 / 7	TYR A  93 TRP A 147 TYR A 188 GLU A 193 TYR A 195	None	0.83A	78.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1lt8	BETAINE-HOMOCYSTEINE METHYLTRANSFERASE (Homo sapiens)	4 / 8	TYR A 284 ILE A 281 ASP A 220 SER A 224	None None CIT  A 701 (-2.8A) None	1.10A	19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1sl5	MDC-SIGN1B TYPE I ISOFORM (Homo sapiens)	4 / 8	THR A 261 TYR A 268 ARG A 312 ILE A 376	None	0.92A	20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1sl6	C-TYPE LECTIN DC-SIGNR (Homo sapiens)	4 / 8	THR A 273 TYR A 280 ARG A 324 ILE A 388	None	0.94A	19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1um1	KIAA1849 PROTEIN (Homo sapiens)	4 / 8	TYR A  39 GLN A  41 ILE A 103 ASP A  27	None	1.13A	18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1v62	KIAA1719 PROTEIN (Homo sapiens)	4 / 8	ARG A  48 ILE A  49 ASP A  65 SER A 104	None	1.12A	20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	2it6	CD209 ANTIGEN (Homo sapiens)	4 / 8	THR A 261 TYR A 268 ARG A 312 ILE A 376	None	0.95A	20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	2uyy	N-PAC PROTEIN (Homo sapiens)	4 / 8	THR A 327 TYR A 357 ARG A 352 ILE A 351	None	1.01A	20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3hhr	HUMAN GROWTH HORMONE (Homo sapiens)	4 / 8	GLN A 122 MET A 125 ILE A 121 SER A  85	None	1.11A	19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3nvq	SEMAPHORIN-7A (Homo sapiens)	4 / 8	TYR A 408 GLN A 304 ARG A 245 ASP A 432	None None None NDG  A   4 (-3.9A)	1.08A	17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3pbl	D(3) DOPAMINE RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.00A	18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3qak	ADENOSINE RECEPTOR A2A,LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.03A	17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3rwr	DNA REPAIR PROTEIN XRCC4 (Homo sapiens)	4 / 8	THR A  37 GLN A  21 ARG A   3 ILE A   5	None	0.80A	20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3u7u	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	4 / 8	THR A 151 ARG A 171 ILE A 141 SER A 148	None	1.06A	16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3ut3	PLASMINOGEN ACTIVATOR INHIBITOR 1 (Homo sapiens)	4 / 8	THR A  49 GLN A  47 MET A  62 ILE A  58	None	1.14A	19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3v2y	SPHINGOSINE 1-PHOSPHATE RECEPTOR 1, LYSOZYME CHIMERA (E.C.3.2.1.17) (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.13A	17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3vw7	PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.02A	17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4bkg	SMALL UBIQUITIN-RELATED MODIFIER 2 (Homo sapiens)	4 / 8	GLN A  88 ILE A  58 ASP A  26 SER A  28	None	1.12A	19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4lde	LYSOZYME, BETA-2 ADRENERGIC RECEPTOR (Escherichia virus T4; Homo sapiens)	4 / 8	THR A 899 TYR A 890 ILE A 882 SER A 901	None	1.08A	20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4wn5	HYPOXIA-INDUCIBLE FACTOR 3-ALPHA (Homo sapiens)	4 / 8	TYR A 275 ARG A 305 ILE A 278 ASP A 284	None	1.00A	19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4wtv	PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-BETA,ENDOLYSIN,PHO SPHATIDYLINOSITOL 4-KINASE TYPE 2-BETA (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1033 TYR A1024 ILE A1016 SER A1035	None	1.14A	17.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zjs	ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA,SOLUBLE ACETYLCHOLINE RECEPTOR,ACETYLCHOLI NE RECEPTOR SUBUNIT ALPHA,SOLUBLE ACETYLCHOLINE RECEPTOR (Aplysia californica; Homo sapiens)	7 / 8	THR A  36 GLN A  57 ARG A  59 MET A 116 ILE A 118 ASP A 164 SER A 167	None	0.44A	78.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zwj	CHIMERA PROTEIN OF HUMAN RHODOPSIN, MOUSE S-ARRESTIN, AND T4 ENDOLYSIN (Escherichia virus T4; Homo sapiens; Mus musculus)	4 / 8	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.03A	13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5bz6	LYSOZYME,CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL (Escherichia virus T4; Homo sapiens)	4 / 8	THR A  34 TYR A  25 ILE A  17 SER A  36	None	1.12A	18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5eut	PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA,ENDOLYSIN,PH OSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1036 TYR A1027 ILE A1019 SER A1038	None	1.07A	18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5v88	LYSOZYME,DCN1-LIKE PROTEIN 1 (Escherichia virus T4; Homo sapiens)	4 / 8	THR A  34 TYR A  25 ILE A  17 SER A  36	None	1.00A	19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5zbq	NEUROPEPTIDE Y RECEPTOR TYPE 1,T4 LYSOZYME (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1033 TYR A1024 ILE A1016 SER A1035	None	1.00A	17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	6d1w	POLYCYSTIN-2 (Homo sapiens)	4 / 8	THR A 260 GLN A 255 ARG A 251 SER A 286	None	0.95A	17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	6ffh	METABOTROPIC GLUTAMATE RECEPTOR 5,ENDOLYSIN (Escherichia virus T4; Homo sapiens)	4 / 8	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.02A	17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	2efl	FORMIN-BINDING PROTEIN 1 (Homo sapiens)	4 / 7	TYR A 272 TYR A  67 CYH A  70 GLU A  64	None	1.34A	18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3tsw	TIGHT JUNCTION PROTEIN ZO-1 (Homo sapiens)	4 / 7	TYR A 633 TRP A 557 GLU A 530 TYR A 527	None	1.25A	20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4d01	NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 (Homo sapiens)	4 / 7	TYR A  95 TRP A 151 GLU A 197 TYR A 199	EDO  A1220 ( 4.1A) None None EDO  A1220 (-3.8A)	0.77A	27.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XYT_H_TC9H1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4hqp	ALPHA7 NICOTINIC RECEPTOR CHIMERA (Homo sapiens; Lymnaea stagnalis)	4 / 7	TYR A  91 TRP A 145 TYR A 184 TYR A 191	None	0.63A	36.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4s0u	NKG2-D TYPE II INTEGRAL MEMBRANE PROTEIN RETINOIC ACID EARLY TRANSCRIPT 1L PROTEIN (Homo sapiens)	4 / 7	TRP C 139 TYR A 199 GLU A 201 TYR C 184	None	1.25A	21.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XYT_H_TC9H1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zjs	ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA,SOLUBLE ACETYLCHOLINE RECEPTOR,ACETYLCHOLI NE RECEPTOR SUBUNIT ALPHA,SOLUBLE ACETYLCHOLINE RECEPTOR (Aplysia californica; Homo sapiens)	5 / 7	TYR A  93 TRP A 147 TYR A 188 GLU A 193 TYR A 195	None	0.91A	78.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1h7c	TUBULIN-SPECIFIC CHAPERONE A (Homo sapiens)	4 / 7	GLN A  53 MET A  40 ILE A  37 SER A  60	None	1.19A	19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1lt8	BETAINE-HOMOCYSTEINE METHYLTRANSFERASE (Homo sapiens)	4 / 7	TYR A 284 ILE A 281 ASP A 220 SER A 224	None None CIT  A 701 (-2.8A) None	1.12A	19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1mk2	SMAD 3 (Homo sapiens)	4 / 7	MET A 373 ILE A 395 ASP A 257 SER A 263	None	1.14A	19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1um1	KIAA1849 PROTEIN (Homo sapiens)	4 / 7	TYR A  39 GLN A  41 ILE A 103 ASP A  27	None	1.11A	18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1v5w	MEIOTIC RECOMBINATION PROTEIN DMC1/LIM15 HOMOLOG (Homo sapiens)	4 / 7	THR A 267 GLN A 269 ASP A 223 SER A 136	None	1.16A	20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3hhr	HUMAN GROWTH HORMONE (Homo sapiens)	4 / 7	GLN A 122 MET A 125 ILE A 121 SER A  85	None	1.21A	19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3pbl	D(3) DOPAMINE RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	4 / 7	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.05A	18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3qak	ADENOSINE RECEPTOR A2A,LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	4 / 7	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.06A	17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3ut3	PLASMINOGEN ACTIVATOR INHIBITOR 1 (Homo sapiens)	4 / 7	THR A  49 GLN A  47 MET A  62 ILE A  58	None	1.13A	19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3vw7	PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME (Escherichia virus T4; Homo sapiens)	4 / 7	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.03A	17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4lde	LYSOZYME, BETA-2 ADRENERGIC RECEPTOR (Escherichia virus T4; Homo sapiens)	4 / 7	THR A 899 TYR A 890 ILE A 882 SER A 901	None	1.12A	20.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zjs	ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA,SOLUBLE ACETYLCHOLINE RECEPTOR,ACETYLCHOLI NE RECEPTOR SUBUNIT ALPHA,SOLUBLE ACETYLCHOLINE RECEPTOR (Aplysia californica; Homo sapiens)	6 / 7	THR A  36 GLN A  57 MET A 116 ILE A 118 ASP A 164 SER A 167	None	0.42A	78.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zwj	CHIMERA PROTEIN OF HUMAN RHODOPSIN, MOUSE S-ARRESTIN, AND T4 ENDOLYSIN (Escherichia virus T4; Homo sapiens; Mus musculus)	4 / 7	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.08A	13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5cni	METABOTROPIC GLUTAMATE RECEPTOR 2 (Homo sapiens)	4 / 7	GLN A 191 MET A 195 ILE A 317 SER A 376	None	1.21A	17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5eut	PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA,ENDOLYSIN,PH OSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA (Escherichia virus T4; Homo sapiens)	4 / 7	THR A1036 TYR A1027 ILE A1019 SER A1038	None	1.11A	18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5v88	LYSOZYME,DCN1-LIKE PROTEIN 1 (Escherichia virus T4; Homo sapiens)	4 / 7	THR A  34 TYR A  25 ILE A  17 SER A  36	None	1.03A	19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5y2z	LEUCINE-RICH GLIOMA-INACTIVATED PROTEIN 1 (Homo sapiens)	4 / 7	THR B 545 GLN B 230 ILE B 547 SER B 236	None	1.11A	17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5y31	LEUCINE-RICH GLIOMA-INACTIVATED PROTEIN 1 (Homo sapiens)	4 / 7	THR B 545 GLN B 230 ILE B 547 SER B 236	None	1.14A	16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5zbq	NEUROPEPTIDE Y RECEPTOR TYPE 1,T4 LYSOZYME (Escherichia virus T4; Homo sapiens)	4 / 7	THR A1033 TYR A1024 ILE A1016 SER A1035	None	1.01A	17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	6ffh	METABOTROPIC GLUTAMATE RECEPTOR 5,ENDOLYSIN (Escherichia virus T4; Homo sapiens)	4 / 7	THR A1034 TYR A1025 ILE A1017 SER A1036	None	1.06A	17.05