POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W4X_A_STZA1591_1 (O-GLCNACASE BT_4395)	5m7r	PROTEIN O-GLCNACASE (Homo sapiens)	7 / 11	ASP A 174 CYH A 215 TYR A 219 THR A 250 VAL A 254 ASP A 285 TYR A 286	None	0.83A	23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W4X_A_STZA1591_1 (O-GLCNACASE BT_4395)	5m7r	PROTEIN O-GLCNACASE (Homo sapiens)	9 / 11	CYH A 215 TYR A 219 THR A 250 VAL A 254 TRP A 278 ASN A 280 ASP A 285 TYR A 286 ASN A 313	None	0.43A	23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W4X_A_STZA1591_1 (O-GLCNACASE BT_4395)	5uhk	O-GLCNACASE TIM-BARREL DOMAIN (Homo sapiens)	10 / 11	ASP A 174 CYH A 215 TYR A 219 THR A 250 VAL A 254 TRP A 278 ASN A 280 ASP A 285 TYR A 286 ASN A 313	GOL  A 501 (-3.1A) GOL  A 501 ( 4.0A) GOL  A 501 (-3.3A) GOL  A 501 (-4.4A) None GOL  A 501 (-3.6A) GOL  A 501 (-3.4A) GOL  A 502 (-2.9A) None GOL  A 502 (-3.4A)	0.55A	21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W4X_A_STZA1591_1 (O-GLCNACASE BT_4395)	5uhp	O-GLCNACASE TIM-BARREL DOMAIN (Homo sapiens)	10 / 11	ASP A 174 CYH A 215 TYR A 219 THR A 250 VAL A 254 TRP A 278 ASN A 280 ASP A 285 TYR A 286 ASN A 313	GOL  A 501 (-2.5A) GOL  A 501 ( 3.9A) GOL  A 501 (-3.7A) GOL  A 501 (-4.2A) GOL  A 501 (-4.2A) GOL  A 501 (-3.8A) GOL  A 501 (-3.4A) None None None	0.57A	22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W4X_A_STZA1591_1 (O-GLCNACASE BT_4395)	5vvo	PROTEIN O-GLCNACASE (Homo sapiens)	6 / 11	ASP A 174 CYH A 215 TYR A 219 THR A 250 VAL A 254 TYR A 286	None	0.87A	23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W4X_A_STZA1591_1 (O-GLCNACASE BT_4395)	5vvo	PROTEIN O-GLCNACASE (Homo sapiens)	9 / 11	CYH A 215 TYR A 219 THR A 250 VAL A 254 TRP A 278 ASN A 280 ASP A 285 TYR A 286 ASN A 313	None	0.42A	23.95