POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWW_A_SFXA801_1 (TRANSPORTER)	1z6t	APOPTOTIC PROTEASE ACTIVATING FACTOR 1 (Homo sapiens)	5 / 12	GLY A 159 LEU A 163 ILE A 152 ALA A 165 ASP A 243	ADP  A 900 (-3.2A) None None None ADP  A 900 ( 4.7A)	1.00A	19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWW_A_SFXA801_1 (TRANSPORTER)	3kmu	INTEGRIN-LINKED KINASE (Homo sapiens)	5 / 12	TYR A 274 ILE A 327 PHE A 287 ALA A 294 PHE A 297	None	0.99A	19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWW_A_SFXA801_1 (TRANSPORTER)	3mop	MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88 (Homo sapiens)	5 / 12	LEU A  75 GLY A  72 LEU A  74 GLN A  67 PHE A  56	None	1.05A	12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWW_A_SFXA801_1 (TRANSPORTER)	3wsy	SORTILIN-RELATED RECEPTOR (Homo sapiens)	5 / 12	LEU A 209 LEU A 219 TYR A 168 ILE A 178 PHE A 237	None	0.94A	22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWW_A_SFXA801_1 (TRANSPORTER)	4qmg	STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 12	LEU A 223 GLY A 275 ILE A 226 ALA A 308 ASP A 298	None	1.11A	20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWW_A_SFXA801_1 (TRANSPORTER)	4zaj	ARGININE--TRNA LIGASE, CYTOPLASMIC (Homo sapiens)	5 / 12	LEU A 394 GLY A 395 TYR A 428 ILE A 431 PHE A 446	None	1.11A	21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWW_A_SFXA801_1 (TRANSPORTER)	5k5t	EXTRACELLULAR CALCIUM-SENSING RECEPTOR (Homo sapiens)	5 / 12	GLY A  35 LEU A  34 ARG A  96 GLN A  27 ILE A 139	None	1.00A	20.92