POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A69_M_RPTM8002_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		5 / 12ASP A 593
ARG A 327
HIS A 594
ILE A 330
GLU A 282
None
CL  A 816 (-3.1A)
None
CSO  A 316 ( 4.4A)
TRS  A 824 ( 4.6A)
1.27A20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEH_A_RPTA601_1
(SCAFFOLD PROTEIN D13)		5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens)		5 / 10GLN A 331
PRO A  12
VAL A  39
PHE A  30
PHE A  28
None
1.39A20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEH_A_RPTA601_1
(SCAFFOLD PROTEIN D13)		5u68 MPE8
(Homo
sapiens)		5 / 10PRO E 128
SER E  69
VAL E  56
PHE E 130
PHE E 264
None
1.18A19.21