POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	1tf0	SERUM ALBUMIN (Homo sapiens)	5 / 12	LEU A 430 GLY A 431 PHE A 403 ALA A 449 LEU A 387	None	0.71A	21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	1zkc	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE LIKE 2 (Homo sapiens)	5 / 12	LEU A 366 GLY A 398 LEU A 293 ARG A 399 ILE A 382	None	1.05A	16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	2g76	D-3-PHOSPHOGLYCERATE DEHYDROGENASE (Homo sapiens)	5 / 12	LEU A  50 GLY A  49 LEU A   9 PHE A 302 LEU A  14	None	0.86A	19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	2nq3	ITCHY HOMOLOG E3 UBIQUITIN PROTEIN LIGASE (Homo sapiens)	5 / 12	LEU A 142 GLY A 141 LEU A 113 ILE A 102 LEU A  79	None	0.96A	14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	3enp	TP53RK-BINDING PROTEIN (Homo sapiens)	5 / 12	GLY A  27 LEU A  29 ARG A  30 ILE A 105 ALA A  33	None	1.02A	15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	3wzf	ASPARTATE AMINOTRANSFERASE, CYTOPLASMIC (Homo sapiens)	5 / 12	LEU A 174 GLY A 172 LEU A 170 ILE A 208 LEU A 188	None	0.74A	19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	4z3k	SEPIAPTERIN REDUCTASE (Homo sapiens)	6 / 12	LEU A  27 GLY A   1 LEU A   2 GLN A  90 ALA A   5 LEU A  58	None	1.26A	20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	5fbh	EXTRACELLULAR CALCIUM-SENSING RECEPTOR (Homo sapiens)	5 / 12	LEU B  34 GLY B  35 ILE B 427 ALA B 457 LEU B 464	None	0.96A	20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	5k5t	EXTRACELLULAR CALCIUM-SENSING RECEPTOR (Homo sapiens)	5 / 12	LEU A  34 GLY A  35 ILE A 427 ALA A 457 LEU A 464	None	1.02A	20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	5n6c	D-3-PHOSPHOGLYCERATE DEHYDROGENASE (Homo sapiens)	5 / 12	LEU A  51 GLY A  50 LEU A  10 PHE A 303 LEU A  15	None	0.85A	9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	5wai	POLYCOMB PROTEIN SUZ12 (Homo sapiens)	5 / 12	GLY B 484 TYR B 478 ILE B 487 ALA B 444 LEU B 467	None	1.03A	8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	5whr	INDOLEAMINE 2,3-DIOXYGENASE 1 (Homo sapiens)	5 / 12	LEU A 277 GLY A 278 LEU A 276 TYR A 332 LEU A 196	None	0.95A	10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	6g79	5-HYDROXYTRYPTAMINE RECEPTOR 1B GUANINE NUCLEOTIDE-BINDING PROTEIN G(O) SUBUNIT ALPHA (Homo sapiens)	5 / 12	LEU A 343 GLY A 342 LEU A 338 ILE S 231 ALA S 150	None	1.05A	10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM8_A_RFXA603_1 (TRANSPORTER)	1by1	PROTEIN (PIX) (Homo sapiens)	5 / 12	ALA A 133 GLY A 144 SER A 135 GLY A 137 THR A  34	None	1.19A	16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM8_A_RFXA603_1 (TRANSPORTER)	1cjl	PROCATHEPSIN L (Homo sapiens)	5 / 12	ALA A  73 TYR A  72 GLY A  86 PHE A 112 ASP A  79	None	1.15A	19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM8_A_RFXA603_1 (TRANSPORTER)	1z68	FIBROBLAST ACTIVATION PROTEIN, ALPHA SUBUNIT (Homo sapiens)	5 / 12	VAL A 540 TYR A 541 GLY A 593 SER A 624 GLY A 627	None	1.13A	21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM8_A_RFXA603_1 (TRANSPORTER)	2iq1	PROTEIN PHOSPHATASE 2C KAPPA, PPM1K (Homo sapiens)	5 / 12	VAL A 125 ALA A 124 GLY A 207 ASP A 109 THR A 297	None None None MG  A   1 ( 4.9A) None	1.17A	18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM8_A_RFXA603_1 (TRANSPORTER)	4da1	PROTEIN PHOSPHATASE 1K, MITOCHONDRIAL (Homo sapiens)	5 / 12	VAL A 125 ALA A 124 GLY A 207 ASP A 109 THR A 297	None None None MG  A 504 ( 4.7A) None	1.11A	21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM8_A_RFXA603_1 (TRANSPORTER)	4u1r	ATP-DEPENDENT 6-PHOSPHOFRUCTOKINAS E, PLATELET TYPE (Homo sapiens)	5 / 12	VAL A  43 GLY A 172 SER A 323 GLY A 326 THR A  31	None	1.17A	23.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MM8_A_RFXA603_1 (TRANSPORTER)	5i6z	SODIUM-DEPENDENT SEROTONIN TRANSPORTER (Homo sapiens)	8 / 12	TYR A  95 ASP A  98 ALA A 173 TYR A 175 TYR A 176 GLY A 338 GLY A 442 THR A 497	None	0.91A	32.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MM8_A_RFXA603_1 (TRANSPORTER)	5i6z	SODIUM-DEPENDENT SEROTONIN TRANSPORTER (Homo sapiens)	8 / 12	TYR A  95 ASP A  98 TYR A 175 TYR A 176 GLY A 338 SER A 439 GLY A 442 THR A 497	None	1.11A	32.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM8_A_RFXA603_1 (TRANSPORTER)	5vbu	CYTOCHROME P450 21-HYDROXYLASE (Homo sapiens)	5 / 12	VAL A 360 ALA A 363 GLY A 431 GLY A 423 THR A 296	HEM  A 501 ( 4.3A) HEM  A 501 ( 3.7A) HEM  A 501 (-3.6A) HEM  A 501 ( 4.4A) HEM  A 501 (-3.7A)	1.21A	22.75