POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		1jy1 TYROSYL-DNA
PHOSPHODIESTERASE
(Homo
sapiens)		5 / 12VAL A 227
TYR A 537
ALA A 332
SER A 334
LEU A 335
None
0.93A21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		4k3j HEPATOCYTE GROWTH
FACTOR
(Homo
sapiens)		5 / 12VAL A 687
ALA A 659
GLY A 675
SER A 522
LEU A 530
None
0.89A18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		4owt INTEGRATOR COMPLEX
SUBUNIT 3
(Homo
sapiens)		5 / 12VAL A 149
ALA A 112
VAL A 157
GLY A 159
ALA A 160
None
1.06A19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		5dot CARBAMOYL-PHOSPHATE
SYNTHASE [AMMONIA],
MITOCHONDRIAL
(Homo
sapiens)		5 / 12VAL A 425
ALA A 513
GLY A 535
ALA A 742
LEU A 743
None
0.96A16.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		5ikr PROSTAGLANDIN G/H
SYNTHASE 2
(Homo
sapiens)		11 / 12HIS A  90
GLN A 192
VAL A 349
LEU A 352
TYR A 355
TRP A 387
ALA A 516
VAL A 523
ALA A 527
SER A 530
LEU A 531
None
None
ID8  A 601 (-3.9A)
ID8  A 601 (-4.1A)
ID8  A 601 (-3.8A)
COH  A 602 (-4.5A)
None
ID8  A 601 (-3.6A)
ID8  A 601 (-3.5A)
ID8  A 601 (-2.7A)
ID8  A 601 (-3.5A)
0.68A99.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		5ikr PROSTAGLANDIN G/H
SYNTHASE 2
(Homo
sapiens)		11 / 12HIS A  90
GLN A 192
VAL A 349
LEU A 352
TYR A 355
TRP A 387
ALA A 516
VAL A 523
GLY A 526
ALA A 527
LEU A 531
None
None
ID8  A 601 (-3.9A)
ID8  A 601 (-4.1A)
ID8  A 601 (-3.8A)
COH  A 602 (-4.5A)
None
ID8  A 601 (-3.6A)
ID8  A 601 (-3.5A)
ID8  A 601 (-3.5A)
ID8  A 601 (-3.5A)
0.45A99.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		5m32 PROTEASOME SUBUNIT
BETA TYPE-2
(Homo
sapiens)		5 / 12LEU J   4
TYR J 117
GLY J 135
ALA J 136
LEU J 140
None
1.02A16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		5nug CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens)		5 / 12VAL A4309
LEU A4312
TRP A4320
GLY A4152
ALA A4155
None
1.03A7.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		6ez8 HUNTINGTIN
(Homo
sapiens)		5 / 12VAL A2782
ALA A2745
GLY A2777
ALA A2778
LEU A2767
None
1.09A7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		1do5 HUMAN COPPER
CHAPERONE FOR
SUPEROXIDE DISMUTASE
DOMAIN II
(Homo
sapiens)		3 / 3ARG A 104
ILE A 115
PHE A 105
None
0.74A14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		1lpb LIPASE
(Homo
sapiens)		3 / 3ARG B  71
ILE B 102
PHE B  72
None
0.75A20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		1o5t TRYPTOPHANYL-TRNA
SYNTHETASE
(Homo
sapiens)		3 / 3ARG A 133
ILE A 136
PHE A 131
None
0.76A20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		1r4n UBIQUITIN-ACTIVATING
ENZYME E1C
(Homo
sapiens)		3 / 3ARG B  95
ILE B  83
PHE B  94
None
0.76A22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		1svc PROTEIN (NUCLEAR
FACTOR KAPPA-B
(NF-KB))
(Homo
sapiens)		3 / 3ARG P  59
ILE P 142
PHE P  58
None
0.64A20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		1xdv SON OF SEVENLESS
PROTEIN HOMOLOG 1
(Homo
sapiens)		3 / 3ARG A 304
ILE A 245
PHE A 311
None
0.76A21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		2b2y CHROMODOMAIN-HELICAS
E-DNA-BINDING
PROTEIN 1
(Homo
sapiens)		3 / 3ARG C  18
ILE C  62
PHE C  19
None
0.76A11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		2o61 TRANSCRIPTION FACTOR
P65/INTERFERON
REGULATORY FACTOR
7/INTERFERON
REGULATORY FACTOR 3
FUSION PROTEIN
(Homo
sapiens)		3 / 3ARG A  35
ILE A 118
PHE A  34
None
0.53A20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		3h5c PROTEIN Z-DEPENDENT
PROTEASE INHIBITOR
(Homo
sapiens)		3 / 3ARG A 337
ILE A 339
PHE A 340
None
0.74A22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		3kv4 PHD FINGER PROTEIN 8
(Homo
sapiens)		3 / 3ARG A 380
ILE A 375
PHE A 379
None
0.74A20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		4deq NEUROPILIN-1,
VASCULAR ENDOTHELIAL
GROWTH FACTOR A
(Homo
sapiens)		3 / 3ARG A  61
ILE A 127
PHE A  62
None
0.75A16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		4ruh CYTOSOLIC
NON-SPECIFIC
DIPEPTIDASE
(Homo
sapiens)		3 / 3ARG A 159
ILE A  96
PHE A 160
None
0.68A22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		4uow TITIN
(Homo
sapiens)		3 / 3ARG 1  57
ILE 1  69
PHE 1  56
None
0.69A11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		5ddb MENIN
(Homo
sapiens)		3 / 3ARG A 415
ILE A 420
PHE A 416
None
0.76A22.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		5ikr PROSTAGLANDIN G/H
SYNTHASE 2
(Homo
sapiens)		3 / 3ARG A 513
ILE A 517
PHE A 518
None
0.15A99.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		5vi6 HISTONE DEACETYLASE
8
(Homo
sapiens)		3 / 3ARG A 353
ILE A 235
PHE A 277
None
0.67A20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		6b0t FASCIN
(Homo
sapiens)		3 / 3ARG A 217
ILE A  12
PHE A 216
C7V  A 501 (-3.8A)
None
C7V  A 501 (-3.2A)
0.66A10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		6f9s PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX6
(Homo
sapiens)		3 / 3ARG A 396
ILE A 398
PHE A 394
None
0.72A8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens)		5 / 12GLN A  71
ALA A  67
GLY A 106
ALA A 195
SER A 194
None
1.09A22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		1jy1 TYROSYL-DNA
PHOSPHODIESTERASE
(Homo
sapiens)		5 / 12VAL A 227
TYR A 537
ALA A 332
SER A 334
LEU A 335
None
0.98A21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		1zy8 DIHYDROLIPOYL
DEHYDROGENASE,
MITOCHONDRIAL
(Homo
sapiens)		5 / 12SER A  53
GLY A 170
ALA A 171
SER A 167
LEU A 275
FAD  A4750 ( 3.7A)
None
None
None
None
1.11A20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		4iw4 MANNAN-BINDING
LECTIN SERINE
PROTEASE 3
(Homo
sapiens)		5 / 12VAL E 499
SER E 515
ALA E 512
GLY E 502
LEU E 467
None
1.08A19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		4k3j HEPATOCYTE GROWTH
FACTOR
(Homo
sapiens)		5 / 12VAL A 687
ALA A 659
GLY A 675
SER A 522
LEU A 530
None
0.90A18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		4owt INTEGRATOR COMPLEX
SUBUNIT 3
(Homo
sapiens)		5 / 12VAL A 149
ALA A 112
VAL A 157
GLY A 159
ALA A 160
None
1.09A19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		5dot CARBAMOYL-PHOSPHATE
SYNTHASE [AMMONIA],
MITOCHONDRIAL
(Homo
sapiens)		5 / 12VAL A 425
ALA A 513
GLY A 535
ALA A 742
LEU A 743
None
0.95A16.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		5ikr PROSTAGLANDIN G/H
SYNTHASE 2
(Homo
sapiens)		12 / 12HIS A  90
GLN A 192
VAL A 349
SER A 353
TYR A 355
TRP A 387
ALA A 516
VAL A 523
GLY A 526
ALA A 527
SER A 530
LEU A 531
None
None
ID8  A 601 (-3.9A)
ID8  A 601 ( 4.7A)
ID8  A 601 (-3.8A)
COH  A 602 (-4.5A)
None
ID8  A 601 (-3.6A)
ID8  A 601 (-3.5A)
ID8  A 601 (-3.5A)
ID8  A 601 (-2.7A)
ID8  A 601 (-3.5A)
0.53A99.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		6aqf ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A
(Escherichia
coli;
Homo
sapiens)		5 / 12VAL A 186
ALA A  99
VAL A 239
ALA A 243
LEU A 247
None
None
None
None
CLR  A1202 ( 4.3A)
1.05A10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		6ez8 HUNTINGTIN
(Homo
sapiens)		5 / 12VAL A2782
ALA A2745
GLY A2777
ALA A2778
LEU A2767
None
1.06A7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		2d58 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Homo
sapiens)		4 / 4LEU A  70
ARG A  72
ILE A  65
PHE A  57
None
1.24A12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		2zkm 1-PHOSPHATIDYLINOSIT
OL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-2
(Homo
sapiens)		4 / 4LEU X 215
ARG X 218
ILE X 725
PHE X 689
None
1.32A21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		3c6g CYTOCHROME P450 2R1
(Homo
sapiens)		4 / 4LEU A 377
ARG A 109
ILE A 401
PHE A 380
None
HEM  A 601 (-2.4A)
None
None
1.31A20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		3d5o SERUM AMYLOID
P-COMPONENT
(Homo
sapiens)		4 / 4LEU A 157
ARG A  38
ILE A 154
PHE A  37
None
1.18A16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		3ibj CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE
(Homo
sapiens)		4 / 4LEU A 738
ARG A 641
ILE A 737
PHE A 642
None
1.12A20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		3mtl CELL DIVISION
PROTEIN KINASE 16
(Homo
sapiens)		4 / 4LEU A 371
ARG A 376
ILE A 374
PHE A 375
None
1.17A20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		3o4o INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN
(Homo
sapiens)		4 / 4LEU B  79
ARG B  82
ILE B  72
PHE B  81
None
1.33A20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		4oya ADENYLATE CYCLASE
TYPE 10
(Homo
sapiens)		4 / 4LEU A 166
ARG A  33
ILE A 314
PHE A 157
1VE  A 501 (-3.9A)
None
None
None
1.09A22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		5a3f DYNAMIN 3
(Homo
sapiens)		4 / 4LEU A 435
ARG A 343
ILE A 344
PHE A 340
None
1.34A22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		5h64 SERINE/THREONINE-PRO
TEIN KINASE MTOR
(Homo
sapiens)		4 / 4LEU A 955
ARG A 960
ILE A 958
PHE A 959
None
1.15A11.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		5ikr PROSTAGLANDIN G/H
SYNTHASE 2
(Homo
sapiens)		4 / 4LEU A 352
ARG A 513
ILE A 517
PHE A 518
ID8  A 601 (-4.1A)
None
None
None
0.68A99.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		5nug CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens)		4 / 4LEU A2723
ARG A2684
ILE A2680
PHE A2727
None
ATP  A4802 (-3.7A)
None
None
1.18A7.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens)		4 / 4LEU A  43
ARG A  39
ILE A 351
PHE A  38
None
0.89A21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		6c01 ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 3
(Homo
sapiens)		4 / 4LEU A 174
ARG A 170
ILE A 495
PHE A 169
None
1.26A9.45