POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A68_C_RBTC8001_1 (DNA-DIRECTED RNA POLYMERASE BETA CHAIN RNA POLYMERASE SIGMA FACTOR RPOD)	5a31	ANAPHASE-PROMOTING COMPLEX SUBUNIT 1 (Homo sapiens)	5 / 11	ARG A1607 GLN A1604 PHE A1592 SER A1133 PRO A1128	None	1.34A	21.79 15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	1a1z	FADD PROTEIN (Homo sapiens)	4 / 7	LEU A  67 ARG A  72 GLY A  42 SER A  12	None	0.88A	21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	2dm0	TYROSINE-PROTEIN KINASE TXK (Homo sapiens)	4 / 7	ARG A 109 LEU A 110 ARG A 111 GLY A 105	None	0.98A	19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	2enq	PHOSPHATIDYLINOSITOL -4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM (Homo sapiens)	4 / 7	ASN A 134 ARG A  34 GLY A  41 TYR A  38	None	0.83A	24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	2o8e	DNA MISMATCH REPAIR PROTEIN MSH6 (Homo sapiens)	4 / 7	ASN B 600 LEU B 601 GLY B 557 TYR B 556	None	1.01A	8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	2r3v	MEVALONATE KINASE (Homo sapiens)	4 / 7	ASN A 236 LEU A 234 GLY A 140 SER A 145	None	0.77A	15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	3cw3	ABSENT IN MELANOMA 1 PROTEIN (Homo sapiens)	4 / 7	ARG A  93 GLY A  53 TYR A  46 SER A  55	None	1.01A	20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	4nen	INTEGRIN ALPHA-X INTEGRIN BETA-2 (Homo sapiens)	5 / 7	ARG A 407 LEU B 253 GLY A 387 TYR A 388 SER A 389	None	1.19A	8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	4nen	INTEGRIN ALPHA-X INTEGRIN BETA-2 (Homo sapiens)	5 / 7	ARG A 407 LEU B 253 GLY A 404 TYR A 388 SER A 389	None	1.16A	8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	4um8	INTEGRIN ALPHA-V INTEGRIN BETA-6 (Homo sapiens)	5 / 7	ARG A 245 LEU B 265 GLY A 223 TYR A 224 SER A 225	None	1.27A	10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	4um8	INTEGRIN ALPHA-V INTEGRIN BETA-6 (Homo sapiens)	5 / 7	ARG A 245 LEU B 265 GLY A 242 TYR A 224 SER A 225	None	1.30A	10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	2bzl	TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 14 (Homo sapiens)	5 / 12	VAL A 942 GLU A1013 PRO A1083 VAL A1173 PHE A1172	None	1.47A	20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	2x2u	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET (Homo sapiens)	5 / 12	PHE A 188 VAL A 193 GLN A 187 PRO A 162 ILE A 200	None	1.44A	17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	3u78	LYSINE-SPECIFIC DEMETHYLASE 7 (Homo sapiens)	5 / 12	VAL A 179 VAL A 356 PHE A 214 GLN A 200 ILE A 300	None AKG  A 701 (-4.1A) None E67  A 707 (-3.3A) None	1.37A	21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	4nge	PRESEQUENCE PROTEASE, MITOCHONDRIAL (Homo sapiens)	5 / 12	VAL D  90 PHE D  92 GLN D 289 PRO D 170 PHE D 169	None None MLY  D 290 ( 4.8A) None MLY  D 287 ( 4.5A)	1.38A	20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	4pj6	LEUCYL-CYSTINYL AMINOPEPTIDASE (Homo sapiens)	5 / 12	GLU A 487 VAL A 420 GLN A 469 PHE A 438 ILE A 422	ZN  A1101 ( 1.9A) None None None None	1.41A	21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	4ux8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET (Homo sapiens)	5 / 12	PHE A 188 VAL A 193 GLN A 187 PRO A 162 ILE A 200	None	1.45A	22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	5hkj	COMPLEMENT C1Q SUBCOMPONENT SUBUNIT A,COMPLEMENT C1Q SUBCOMPONENT SUBUNIT C,COMPLEMENT C1Q SUBCOMPONENT SUBUNIT B (Homo sapiens)	5 / 12	VAL A 106 PHE A  42 PHE A  52 GLN A 173 PRO A   6	None	1.06A	22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	5hkj	COMPLEMENT C1Q SUBCOMPONENT SUBUNIT A,COMPLEMENT C1Q SUBCOMPONENT SUBUNIT C,COMPLEMENT C1Q SUBCOMPONENT SUBUNIT B (Homo sapiens)	5 / 12	VAL A 242 PRO A 406 PHE A 402 PHE A 183 PHE A 193	None	1.41A	22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	5i6z	SODIUM-DEPENDENT SEROTONIN TRANSPORTER (Homo sapiens)	5 / 12	VAL A 102 PRO A 196 VAL A 236 PHE A 231 PHE A 407	None	1.35A	20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	5u3p	DH511.4 FAB HEAVY CHAIN DH511.4 FAB LIGHT CHAIN (Homo sapiens)	5 / 12	VAL H   2 PRO L  95 PHE H  27 GLN L  89 ILE H  69	None	1.32A	15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	5wdh	KINESIN-LIKE PROTEIN KIFC1 (Homo sapiens)	5 / 12	VAL A 660 GLU A 570 VAL A 541 PHE A 656 ILE A 464	None	1.35A	21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEC_C_RBTC601_1 (SCAFFOLD PROTEIN D13)	5y3r	DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT (Homo sapiens)	5 / 12	GLU C1354 PHE C1270 GLN C1280 PHE C1296 ILE C1341	None	1.34A	9.18