POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_A_RAUA400_1 (IMINE REDUCTASE)	3o57	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 223 MET A 220 PHE A 216 MET A 196 GLY A 311	None	1.21A	22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_A_RAUA400_1 (IMINE REDUCTASE)	3o57	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 223 MET A 220 TYR A 219 MET A 196 GLY A 311	None	0.90A	22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_A_RAUA400_1 (IMINE REDUCTASE)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	5 / 11	VAL A 169 LEU A 149 MET A 122 SER A 197 GLY A 237	VAL  A 169 ( 0.6A) LEU  A 149 ( 0.6A) MET  A 122 ( 0.0A) SER  A 197 ( 0.0A) GLY  A 237 ( 0.0A)	1.49A	22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_A_RAUA400_1 (IMINE REDUCTASE)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	5 / 11	VAL A 169 LEU A 149 TYR A 145 MET A 122 GLY A 237	VAL  A 169 ( 0.6A) LEU  A 149 ( 0.6A) TYR  A 145 ( 1.3A) MET  A 122 ( 0.0A) GLY  A 237 ( 0.0A)	1.25A	22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_A_RAUA400_1 (IMINE REDUCTASE)	4wzi	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 395 MET A 392 PHE A 388 MET A 368 GLY A 483	None	1.20A	19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_A_RAUA400_1 (IMINE REDUCTASE)	4wzi	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 395 MET A 392 TYR A 391 MET A 368 GLY A 483	None	0.92A	19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_A_RAUA400_1 (IMINE REDUCTASE)	5ohj	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 395 MET A 392 PHE A 388 MET A 368 GLY A 483	None	1.24A	12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_A_RAUA400_1 (IMINE REDUCTASE)	5ohj	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 395 MET A 392 TYR A 391 MET A 368 GLY A 483	None	0.93A	12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_B_RAUB400_1 (IMINE REDUCTASE)	3g4g	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	5 / 11	VAL A 335 LEU A 315 TYR A 311 MET A 288 GLY A 403	None	1.13A	22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_B_RAUB400_1 (IMINE REDUCTASE)	3o57	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 223 MET A 220 TYR A 219 MET A 196 GLY A 311	None	0.90A	22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_B_RAUB400_1 (IMINE REDUCTASE)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	5 / 11	VAL A 169 LEU A 149 TYR A 145 MET A 122 GLY A 237	VAL  A 169 ( 0.6A) LEU  A 149 ( 0.6A) TYR  A 145 ( 1.3A) MET  A 122 ( 0.0A) GLY  A 237 ( 0.0A)	1.23A	22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_B_RAUB400_1 (IMINE REDUCTASE)	4wzi	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 395 MET A 392 PHE A 388 MET A 368 GLY A 483	None	1.21A	19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_B_RAUB400_1 (IMINE REDUCTASE)	4wzi	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 395 MET A 392 TYR A 391 MET A 368 GLY A 483	None	0.93A	19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_B_RAUB400_1 (IMINE REDUCTASE)	5ohj	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 395 MET A 392 TYR A 391 MET A 368 GLY A 483	None	0.94A	12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_B_RAUB400_1 (IMINE REDUCTASE)	5wh6	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	5 / 11	VAL A 169 LEU A 149 TYR A 145 MET A 122 GLY A 237	None	1.20A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_C_RAUC400_1 (IMINE REDUCTASE)	3ddu	PROLYL ENDOPEPTIDASE (Homo sapiens)	5 / 12	TYR A 630 GLY A 557 VAL A 620 LEU A 635 MET A 633	None	1.46A	17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_C_RAUC400_1 (IMINE REDUCTASE)	3o57	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 12	MET A 196 GLY A 311 LEU A 223 MET A 220 PHE A 216	None	1.21A	22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_C_RAUC400_1 (IMINE REDUCTASE)	3o57	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 12	MET A 196 GLY A 311 LEU A 223 MET A 220 TYR A 219	None	0.90A	22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_C_RAUC400_1 (IMINE REDUCTASE)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	5 / 12	MET A 122 GLY A 237 VAL A 169 LEU A 149 TYR A 145	MET  A 122 ( 0.0A) GLY  A 237 ( 0.0A) VAL  A 169 ( 0.6A) LEU  A 149 ( 0.6A) TYR  A 145 ( 1.3A)	1.25A	22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_C_RAUC400_1 (IMINE REDUCTASE)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	5 / 12	MET A 122 SER A 197 GLY A 237 VAL A 169 LEU A 149	MET  A 122 ( 0.0A) SER  A 197 ( 0.0A) GLY  A 237 ( 0.0A) VAL  A 169 ( 0.6A) LEU  A 149 ( 0.6A)	1.49A	22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_C_RAUC400_1 (IMINE REDUCTASE)	4wzi	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 12	MET A 368 GLY A 483 LEU A 395 MET A 392 PHE A 388	None	1.20A	19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_C_RAUC400_1 (IMINE REDUCTASE)	4wzi	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 12	MET A 368 GLY A 483 LEU A 395 MET A 392 TYR A 391	None	0.93A	19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_C_RAUC400_1 (IMINE REDUCTASE)	5jpn	COMPLEMENT C4-A (Homo sapiens)	5 / 12	TYR B1053 SER B1096 GLN B1090 GLY B1152 LEU B1083	None	1.38A	18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_C_RAUC400_1 (IMINE REDUCTASE)	5ohj	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 12	MET A 368 GLY A 483 LEU A 395 MET A 392 PHE A 388	None	1.24A	12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_C_RAUC400_1 (IMINE REDUCTASE)	5ohj	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 12	MET A 368 GLY A 483 LEU A 395 MET A 392 TYR A 391	None	0.94A	12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_D_RAUD400_1 (IMINE REDUCTASE)	3g4g	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	5 / 10	VAL A 335 LEU A 315 TYR A 311 MET A 288 GLY A 403	None	1.14A	22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_D_RAUD400_1 (IMINE REDUCTASE)	3o57	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 10	LEU A 223 MET A 220 PHE A 216 MET A 196 GLY A 311	None	1.21A	22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_D_RAUD400_1 (IMINE REDUCTASE)	3o57	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 10	LEU A 223 MET A 220 TYR A 219 MET A 196 GLY A 311	None	0.90A	22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_D_RAUD400_1 (IMINE REDUCTASE)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	5 / 10	VAL A 169 LEU A 149 TYR A 145 MET A 122 GLY A 237	VAL  A 169 ( 0.6A) LEU  A 149 ( 0.6A) TYR  A 145 ( 1.3A) MET  A 122 ( 0.0A) GLY  A 237 ( 0.0A)	1.24A	22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_D_RAUD400_1 (IMINE REDUCTASE)	4wzi	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 10	LEU A 395 MET A 392 PHE A 388 MET A 368 GLY A 483	None	1.21A	19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_D_RAUD400_1 (IMINE REDUCTASE)	4wzi	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 10	LEU A 395 MET A 392 TYR A 391 MET A 368 GLY A 483	None	0.93A	19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_D_RAUD400_1 (IMINE REDUCTASE)	5ohj	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 10	LEU A 395 MET A 392 PHE A 388 MET A 368 GLY A 483	None	1.24A	12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_D_RAUD400_1 (IMINE REDUCTASE)	5ohj	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 10	LEU A 395 MET A 392 TYR A 391 MET A 368 GLY A 483	None	0.94A	12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_D_RAUD400_1 (IMINE REDUCTASE)	5wh6	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	5 / 10	VAL A 169 LEU A 149 TYR A 145 MET A 122 GLY A 237	None	1.21A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_E_RAUE400_1 (IMINE REDUCTASE)	3o57	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 223 MET A 220 PHE A 216 MET A 196 GLY A 311	None	1.22A	22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_E_RAUE400_1 (IMINE REDUCTASE)	3o57	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 223 MET A 220 TYR A 219 MET A 196 GLY A 311	None	0.90A	22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_E_RAUE400_1 (IMINE REDUCTASE)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	5 / 11	VAL A 169 LEU A 149 TYR A 145 MET A 122 GLY A 237	VAL  A 169 ( 0.6A) LEU  A 149 ( 0.6A) TYR  A 145 ( 1.3A) MET  A 122 ( 0.0A) GLY  A 237 ( 0.0A)	1.24A	22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_E_RAUE400_1 (IMINE REDUCTASE)	4wzi	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 395 MET A 392 PHE A 388 MET A 368 GLY A 483	None	1.21A	19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_E_RAUE400_1 (IMINE REDUCTASE)	4wzi	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 395 MET A 392 TYR A 391 MET A 368 GLY A 483	None	0.93A	19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_E_RAUE400_1 (IMINE REDUCTASE)	5ohj	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 395 MET A 392 PHE A 388 MET A 368 GLY A 483	None	1.25A	12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_E_RAUE400_1 (IMINE REDUCTASE)	5ohj	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 11	LEU A 395 MET A 392 TYR A 391 MET A 368 GLY A 483	None	0.94A	12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G6S_F_RAUF400_1 (IMINE REDUCTASE)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	5 / 10	GLY A 816 VAL A 788 LEU A 813 MET A 809 TYR A 812	None	1.46A	23.24