POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		1aos ARGININOSUCCINATE
LYASE
(Homo
sapiens)		4 / 5GLN A 116
ASP A 120
HIS A  89
GLU A  93
None
1.26A22.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		1d7w MYELOPEROXIDASE
MYELOPEROXIDASE
(Homo
sapiens;
Homo
sapiens)		5 / 5GLN A  91
ASP A  94
HIS A  95
ARG C 239
GLU C 242
HEM  A 605 ( 3.4A)
HEM  A 605 (-2.1A)
CYN  A1844 (-4.1A)
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
0.36A38.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		2wkp NPH1-1, RAS-RELATED
C3 BOTULINUM TOXIN
SUBSTRATE 1
(Avena
sativa;
Homo
sapiens)		4 / 5GLN A 479
HIS A 519
ARG A 521
GLU A 525
None
1.49A20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		5b4w PLEXIN-B1
(Homo
sapiens)		4 / 5GLN A 256
ASP A 255
HIS A 257
GLU A 201
None
1.47A20.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
ASP A 260
HIS A 261
ARG A 405
HEM  A 812 (-3.3A)
HEM  A 812 (-1.1A)
None
HEM  A 812 (-3.7A)
0.30A49.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		5nug CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens)		4 / 5GLN A3667
ASP A3666
ARG A3620
GLU A3624
None
1.31A8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
ASP A 260
HIS A 261
ARG A 405
None
0.48Aundetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
ASP A 260
HIS A 261
GLU A 408
None
0.94Aundetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R4X_A_PZAA598_0
(LACTOPEROXIDASE)		1d7w MYELOPEROXIDASE
(Homo
sapiens)		4 / 5ARG C 239
GLU C 242
PHE C 366
PRO C 220
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
None
None
1.38A45.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA598_0
(LACTOPEROXIDASE)		2e8o SAM DOMAIN AND HD
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens)		4 / 5PHE A  71
ARG A  82
GLU A  81
PHE A  44
None
1.31A12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA598_0
(LACTOPEROXIDASE)		3d3l ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Homo
sapiens)		4 / 5PHE A 627
ARG A 628
GLU A 632
PRO A 654
None
0.97A20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA598_0
(LACTOPEROXIDASE)		3v98 ARACHIDONATE
5-LIPOXYGENASE
(Homo
sapiens)		4 / 5PHE A 637
ARG A 638
GLU A 642
PRO A 664
None
0.92A21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA598_0
(LACTOPEROXIDASE)		6caj TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT BETA
(Homo
sapiens)		4 / 5ARG C 172
GLU C  32
PHE C 272
PRO C 270
None
1.25Aundetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		1d7w MYELOPEROXIDASE
MYELOPEROXIDASE
(Homo
sapiens;
Homo
sapiens)		5 / 5GLN A  91
ASP A  94
HIS A  95
ARG C 239
GLU C 242
HEM  A 605 ( 3.4A)
HEM  A 605 (-2.1A)
CYN  A1844 (-4.1A)
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
0.33A38.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		2f1z UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7
(Homo
sapiens)		4 / 5GLN A 297
ASP A 349
ARG A 301
GLU A 298
None
1.19A20.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
ASP A 260
HIS A 261
ARG A 405
HEM  A 812 (-3.3A)
HEM  A 812 (-1.1A)
None
HEM  A 812 (-3.7A)
0.25A49.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
ASP A 260
HIS A 261
GLU A 408
HEM  A 812 (-3.3A)
HEM  A 812 (-1.1A)
None
HEM  A 812 (-4.2A)
1.02A49.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		5nug CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens)		4 / 5GLN A3667
ASP A3666
ARG A3620
GLU A3624
None
1.43A8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
ASP A 260
HIS A 261
ARG A 405
None
0.48Aundetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
ASP A 260
HIS A 261
GLU A 408
None
1.04Aundetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		1gvl KALLIKREIN 6
(Homo
sapiens)		3 / 3GLU A  77
PHE A  67
GLN A  80
None
0.47A17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		1now BETA-HEXOSAMINIDASE
BETA CHAIN
(Homo
sapiens)		3 / 3GLU A 362
PHE A 380
GLN A 368
None
1.01A20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		2dt6 SPLICING FACTOR 3
SUBUNIT 1
(Homo
sapiens)		3 / 3GLU A 108
PHE A 101
GLN A 107
None
0.75A7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		2llh NUCLEOPHOSMIN
(Homo
sapiens)		3 / 3GLU A   8
PHE A   4
GLN A   7
None
0.96A9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		2xy9 ANGIOTENSIN-CONVERTI
NG ENZYME
(Homo
sapiens)		3 / 3GLU A  43
PHE A 102
GLN A  98
None
0.74A21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		3pqz GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 7
(Homo
sapiens)		3 / 3GLU A 459
PHE A 467
GLN A 465
None
1.01A12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		3sm9 METABOTROPIC
GLUTAMATE RECEPTOR 3
(Homo
sapiens)		3 / 3GLU A  37
PHE A 329
GLN A  42
None
1.00A21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens)		3 / 3GLU A 481
PHE A 396
GLN A 662
None
0.98A21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		4wco C-TYPE LECTIN DOMAIN
FAMILY 2 MEMBER D
(Homo
sapiens)		3 / 3GLU A 118
PHE A  82
GLN A 117
None
0.97A10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		5kzn METABOTROPIC
GLUTAMATE RECEPTOR 2
(Homo
sapiens)		3 / 3GLU A  55
PHE A 348
GLN A  60
None
1.01A23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		5lcw MITOTIC CHECKPOINT
SERINE/THREONINE-PRO
TEIN KINASE BUB1
BETA,MITOTIC
CHECKPOINT
SERINE/THREONINE-PRO
TEIN KINASE BUB1
BETA
(Homo
sapiens)		3 / 3GLU S 166
PHE S 168
GLN S 203
None
0.95A20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		6ct0 DIHYDROLIPOYLLYSINE-
RESIDUE
ACETYLTRANSFERASE
COMPONENT OF
PYRUVATE
DEHYDROGENASE
COMPLEX,
MITOCHONDRIAL
(Homo
sapiens)		3 / 3GLU 0 557
PHE 0 527
GLN 0 559
None
1.01Aundetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		2dkp PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY A MEMBER 5
(Homo
sapiens)		4 / 7VAL A  21
GLY A  25
VAL A  44
ARG A  15
None
0.89A17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		2frw CYTOPLASMIC PROTEIN
NCK2
(Homo
sapiens)		4 / 7ASN A  41
VAL A  25
GLY A  22
VAL A  20
None
0.95A9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		2ipx RRNA
2'-O-METHYLTRANSFERA
SE FIBRILLARIN
(Homo
sapiens)		4 / 7ASN A 210
VAL A 188
ALA A 190
GLY A 172
None
0.63A19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		3h1v GLUCOKINASE
(Homo
sapiens)		4 / 7VAL X 374
SER X 375
ALA X 378
GLY X 294
None
0.84A23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		3mud DNA REPAIR PROTEIN
XRCC4,TROPOMYOSIN
ALPHA-1 CHAIN
(Gallus
gallus;
Homo
sapiens)		4 / 7SER A  53
ALA A  56
GLY A  64
VAL A  67
None
0.70A20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		3q4f DNA REPAIR PROTEIN
XRCC4
(Homo
sapiens)		4 / 7SER C  53
ALA C  56
GLY C  64
VAL C  67
None
0.70A17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		4cqm CARBONYL REDUCTASE
FAMILY MEMBER 4
(Homo
sapiens)		4 / 7VAL B 226
ALA B 177
GLY B 138
ARG B 160
None
0.81A22.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		4hwi HEAT SHOCK COGNATE
71 KDA PROTEIN
(Homo
sapiens)		4 / 7ASN A 235
VAL A 238
VAL A 260
ARG A 264
None
0.72A90.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		4j1y COMPLEMENT C1S
SUBCOMPONENT
(Homo
sapiens)		4 / 7ASN A 480
VAL A 477
ALA A 473
GLY A 462
None
0.93A20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5chx XRCC4-MYH7-1590-1657
(Homo
sapiens)		4 / 7SER A  53
ALA A  56
GLY A  64
VAL A  67
MLY  A  63 ( 3.7A)
MLY  A  63 ( 4.0A)
MLY  A  65 ( 2.4A)
MLY  A  63 ( 3.8A)
0.66A20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5cj0 XRCC4-MYH7-(1631-169
2) CHIMERA PROTEIN
(Homo
sapiens)		4 / 7SER A  53
ALA A  56
GLY A  64
VAL A  67
None
0.72A20.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5fpn HEAT SHOCK-RELATED
70 KDA PROTEIN 2
(Homo
sapiens)		4 / 7ASN A 237
VAL A 240
VAL A 262
ARG A 266
None
0.81A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5fpn HEAT SHOCK-RELATED
70 KDA PROTEIN 2
(Homo
sapiens)		6 / 7VAL A 240
SER A 241
ALA A 244
GLY A 256
VAL A 262
ARG A 266
None
0.18A100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5j1t TORSIN-1A
(Homo
sapiens)		4 / 7VAL A 297
SER A 298
ALA A 301
ARG A 282
None
0.82A22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5mgv PHENYLALANINE--TRNA
LIGASE,
MITOCHONDRIAL
(Homo
sapiens)		4 / 7SER A 121
GLY A 139
VAL A 141
ARG A 143
None
0.85A22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7
(Homo
sapiens)		4 / 7SER C  53
ALA C  56
GLY C  64
VAL C  67
None
0.71A23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		1bd8 P19INK4D CDK4/6
INHIBITOR
(Homo
sapiens)		4 / 7VAL A 123
SER A 124
ALA A 127
GLY A 160
None
0.86A18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		1fu1 DNA REPAIR PROTEIN
XRCC4
(Homo
sapiens)		4 / 7SER A  53
ALA A  56
GLY A  64
VAL A  67
None
0.83A21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		2bwg GMP REDUCTASE I
(Homo
sapiens)		4 / 7VAL A 239
SER A 218
ALA A 236
GLY A 233
None
0.88A24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		2dkp PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY A MEMBER 5
(Homo
sapiens)		4 / 7VAL A  21
GLY A  25
VAL A  44
ARG A  15
None
0.91A17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		2frw CYTOPLASMIC PROTEIN
NCK2
(Homo
sapiens)		4 / 7ASN A  41
VAL A  25
GLY A  22
VAL A  20
None
0.93A9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		2ipx RRNA
2'-O-METHYLTRANSFERA
SE FIBRILLARIN
(Homo
sapiens)		4 / 7ASN A 210
VAL A 188
ALA A 190
GLY A 172
None
0.64A19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		3h1v GLUCOKINASE
(Homo
sapiens)		4 / 7VAL X 374
SER X 375
ALA X 378
GLY X 294
None
0.84A23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		3mud DNA REPAIR PROTEIN
XRCC4,TROPOMYOSIN
ALPHA-1 CHAIN
(Gallus
gallus;
Homo
sapiens)		4 / 7SER A  53
ALA A  56
GLY A  64
VAL A  67
None
0.69A20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		3q4f DNA REPAIR PROTEIN
XRCC4
(Homo
sapiens)		4 / 7SER C  53
ALA C  56
GLY C  64
VAL C  67
None
0.69A17.51