POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	1lw3	MYOTUBULARIN-RELATED PROTEIN 2 (Homo sapiens)	4 / 6	GLY A 130 ALA A 183 LEU A 192 PRO A 185	None	1.00A	16.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	2bzg	THIOPURINE S-METHYLTRANSFERASE (Homo sapiens)	6 / 6	PHE A  40 ARG A 152 GLY A 153 ALA A 157 LEU A 185 PRO A 196	SAH  A1246 (-3.4A) SAH  A1246 (-4.0A) SAH  A1246 (-3.9A) SAH  A1246 ( 3.7A) None None	0.27A	71.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	2vgq	SUGAR ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN,MITOCHONDRIA L ANTIVIRAL-SIGNALING PROTEIN (Escherichia coli; Homo sapiens)	4 / 6	PHE A 258 ALA A 162 LEU A 247 PRO A 159	None	0.92A	20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	2wmo	DEDICATOR OF CYTOKINESIS PROTEIN 9 (Homo sapiens)	4 / 6	PHE A 160 GLY A 162 ALA A 223 LEU A 218	None	0.94A	19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	3hd6	AMMONIUM TRANSPORTER RH TYPE C (Homo sapiens)	4 / 6	GLY A 289 ALA A 292 LEU A 343 PRO A 347	None	0.98A	19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	3n93	MALTOSE BINDING PROTEIN-CRFR2 ALPHA (Homo sapiens)	4 / 6	PHE A-112 ALA A-208 LEU A-123 PRO A-211	None	0.96A	19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	3o3u	MALTOSE-BINDING PERIPLASMIC PROTEIN, ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR (Escherichia coli; Homo sapiens)	4 / 6	PHE N 258 ALA N 162 LEU N 247 PRO N 159	None	0.99A	18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	3oai	MALTOSE-BINDING PERIPLASMIC PROTEIN, MYELIN PROTEIN P0 (Escherichia coli; Homo sapiens)	4 / 6	PHE A 258 ALA A 162 LEU A 247 PRO A 159	None	0.95A	19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	3py7	MALTOSE-BINDING PERIPLASMIC PROTEIN,PAXILLIN LD1,PROTEIN E6 CHIMERA (Deltapapillomavi rus 4; Escherichia coli; Homo sapiens)	4 / 6	PHE A 259 ALA A 163 LEU A 248 PRO A 160	None	0.97A	20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	3vd8	MALTOSE-BINDING PERIPLASMIC PROTEIN, INTERFERON-INDUCIBLE PROTEIN AIM2 (Escherichia coli; Homo sapiens)	4 / 6	PHE A 258 ALA A 162 LEU A 247 PRO A 159	None	0.98A	19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	4egc	MALTOSE-BINDING PERIPLASMIC PROTEIN, HOMEOBOX PROTEIN SIX1 CHIMERA (Escherichia coli; Homo sapiens)	4 / 6	PHE A 258 ALA A 162 LEU A 247 PRO A 159	None	0.98A	17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	4ifp	MALTOSE-BINDING PERIPLASMIC PROTEIN,NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 (Escherichia coli; Homo sapiens)	4 / 6	PHE A 259 ALA A 163 LEU A 248 PRO A 160	None	0.95A	19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	4ikm	MALTOSE-BINDING PERIPLASMIC PROTEIN, CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 8 (Escherichia coli; Homo sapiens)	4 / 6	PHE A 259 ALA A 163 LEU A 248 PRO A 160	None	0.98A	20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	4my2	MALTOSE-BINDING PERIPLASMIC PROTEIN, NORRIN FUSION PROTEIN (Escherichia coli; Homo sapiens)	4 / 6	PHE A 260 ALA A 164 LEU A 249 PRO A 161	None	0.96A	19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	4rwf	MALTOSE TRANSPORTER SUBUNIT, RECEPTOR ACTIVITY-MODIFYING PROTEIN 2, CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR FUSION PROTEIN (Escherichia coli; Homo sapiens)	4 / 6	PHE A 260 ALA A 164 LEU A 249 PRO A 161	None	0.95A	18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	4wrn	MALTOSE-BINDING PERIPLASMIC PROTEIN,UROMODULIN (Escherichia coli; Homo sapiens)	4 / 6	PHE A 282 ALA A 186 LEU A 271 PRO A 183	None	0.98A	18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	4xaj	MALTOSE-BINDING PERIPLASMIC PROTEIN,NUCLEAR RECEPTOR SUBFAMILY 2 GROUP E MEMBER 1 (Escherichia coli; Homo sapiens)	4 / 6	PHE A 260 ALA A 164 LEU A 249 PRO A 161	None	0.98A	18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	4yzf	BAND 3 ANION TRANSPORT PROTEIN (Homo sapiens)	4 / 6	GLY A 763 ALA A 452 LEU A 459 PRO A 458	None	0.92A	13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	5h7n	NLRP12-PYD WITH MBP TAG (Homo sapiens)	4 / 6	PHE A 259 ALA A 163 LEU A 248 PRO A 160	EDO  A 505 (-4.9A) None None None	0.98A	19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	5hzv	MALTOSE-BINDING PERIPLASMIC PROTEIN,ENDOGLIN (Escherichia coli; Homo sapiens)	4 / 6	PHE A 625 ALA A 529 LEU A 614 PRO A 526	None	0.99A	17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	5jj4	MALTOSE-BINDING PERIPLASMIC PROTEIN,SINGLE-STRAN DED DNA CYTOSINE DEAMINASE (Escherichia coli; Homo sapiens)	4 / 6	PHE C 258 ALA C 162 LEU C 247 PRO C 159	None	0.96A	19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	5tj2	SUGAR ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN,GASDERMIN-B FUSION PROTEIN (Escherichia coli; Homo sapiens)	4 / 6	PHE A 258 ALA A 162 LEU A 247 PRO A 159	None	0.96A	18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	5v6y	MALTOSE-BINDING PERIPLASMIC PROTEIN,RECEPTOR ACTIVITY-MODIFYING PROTEIN 1,CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR (Escherichia coli; Homo sapiens)	4 / 6	PHE A 260 ALA A 164 LEU A 249 PRO A 161	None	0.98A	17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	5wdi	UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING PROTEIN A (Homo sapiens)	4 / 6	ARG A 564 GLY A 510 LEU A 549 PRO A 482	None	0.90A	21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	5xfo	PHD FINGER PROTEIN 1 (Homo sapiens)	4 / 6	PHE A 141 ARG A  40 GLY A  44 ALA A 214	None None ZN  A 403 ( 4.1A) None	0.98A	18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	6d43	TRIOSEPHOSPHATE ISOMERASE (Homo sapiens)	4 / 6	ARG B  17 ALA B  46 LEU B  21 PRO B  44	None	0.88A	15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	1cok	PROTEIN (SECOND SPLICE VARIANT P73) (Homo sapiens)	4 / 6	THR A  24 PHE A  23 LEU A   7 LEU A  11	None	1.13A	16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	1fsu	N-ACETYLGALACTOSAMIN E-4-SULFATASE (Homo sapiens)	4 / 6	THR A 164 PHE A 162 LEU A 232 LEU A 234	None	1.03A	17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	1x1f	SIGNAL-TRANSDUCING ADAPTOR PROTEIN 1 (Homo sapiens)	4 / 6	THR A  70 PHE A  82 LEU A  66 LEU A  84	None	1.17A	22.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	2bzg	THIOPURINE S-METHYLTRANSFERASE (Homo sapiens)	5 / 6	HIS A  52 THR A  55 GLN A 179 LEU A 217 LEU A 241	None	0.52A	71.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	2e5o	ACTIVATING SIGNAL COINTEGRATOR 1 (Homo sapiens)	4 / 6	HIS A  36 THR A  34 LEU A  40 LEU A  10	None	0.89A	20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	2ik8	GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT (Homo sapiens)	4 / 6	HIS A 322 THR A 324 PHE A 323 LEU A 266	None	1.07A	19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	3cqc	NUCLEAR PORE COMPLEX PROTEIN NUP133 (Homo sapiens)	4 / 6	HIS B1004 THR B1007 LEU B1054 LEU B1031	None	1.16A	23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	3i4r	NUCLEAR PORE COMPLEX PROTEIN NUP133 (Homo sapiens)	4 / 6	HIS B1004 THR B1007 LEU B1054 LEU B1031	None	1.18A	19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	3zwf	ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 (Homo sapiens)	4 / 6	HIS A  62 THR A  61 PHE A 187 LEU A 180	ZN  A1364 (-3.5A) None None None	1.18A	23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	4ifs	FACT COMPLEX SUBUNIT SSRP1 (Homo sapiens)	4 / 6	HIS A 363 GLN A 252 LEU A 208 LEU A 276	None	0.83A	23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	4iyp	IMMUNOGLOBULIN-BINDI NG PROTEIN 1 (Homo sapiens)	4 / 6	HIS A 196 GLN A 198 LEU A 172 LEU A 168	None	1.18A	22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	4jgv	NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 1 (Homo sapiens)	4 / 6	PHE A 387 GLN A 474 LEU A 468 LEU A 470	None	0.99A	26.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	4wd4	HEME OXYGENASE 1 (Homo sapiens)	4 / 6	HIS A 132 THR A 135 LEU A 118 LEU A  61	None HEM  A 300 ( 4.9A) None None	1.04A	21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	5gvb	WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1 (Homo sapiens)	4 / 6	THR A 637 PHE A 632 GLN A 582 LEU A 603	None	1.07A	20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	5ogs	WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1 (Homo sapiens)	4 / 6	THR A 637 PHE A 632 GLN A 582 LEU A 603	None	1.07A	19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	5ums	FACT COMPLEX SUBUNIT SSRP1 (Homo sapiens)	4 / 6	HIS A 363 GLN A 252 LEU A 208 LEU A 276	None	0.89A	17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	6c0t	CGMP-DEPENDENT PROTEIN KINASE 1 (Homo sapiens)	4 / 6	THR A 460 PHE A 463 LEU A 446 LEU A 492	None	1.14A	16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	6fcx	METHYLENETETRAHYDROF OLATE REDUCTASE (Homo sapiens)	4 / 6	THR A 235 PHE A 237 LEU A 305 LEU A 309	None	1.17A	15.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	2bzg	THIOPURINE S-METHYLTRANSFERASE (Homo sapiens)	6 / 8	PHE A  40 ARG A 152 GLY A 153 VAL A 156 LEU A 185 PRO A 196	SAH  A1246 (-3.4A) SAH  A1246 (-4.0A) SAH  A1246 (-3.9A) None None None	0.35A	71.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	2bzg	THIOPURINE S-METHYLTRANSFERASE (Homo sapiens)	6 / 8	PHE A  40 GLY A 153 VAL A 156 LEU A 185 PRO A 196 ARG A 226	SAH  A1246 (-3.4A) SAH  A1246 (-3.9A) None None None None	0.62A	71.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	2bzg	THIOPURINE S-METHYLTRANSFERASE (Homo sapiens)	5 / 8	PHE A  40 VAL A 156 PRO A 196 ARG A 226 TRP A 230	SAH  A1246 (-3.4A) None None None None	0.78A	71.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	2q7r	ARACHIDONATE 5-LIPOXYGENASE-ACTIV ATING PROTEIN (Homo sapiens)	4 / 8	PHE A  85 GLY A  87 VAL A  15 LEU A  12	None	0.86A	22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	3e0j	DNA POLYMERASE SUBUNIT DELTA-2 (Homo sapiens)	4 / 8	PHE A 341 VAL A 423 LEU A 369 PRO A 399	None	1.14A	19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	3hd6	AMMONIUM TRANSPORTER RH TYPE C (Homo sapiens)	4 / 8	GLY A 289 VAL A 291 LEU A 343 PRO A 347	None	1.03A	19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	3pua	PHD FINGER PROTEIN 2 (Homo sapiens)	4 / 8	PHE A 314 VAL A 105 LEU A 270 PRO A 126	None	0.81A	24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	3u1k	POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERA SE 1, MITOCHONDRIAL (Homo sapiens)	4 / 8	GLY A 161 VAL A 159 PRO A 165 ARG A 192	None	1.14A	16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	4egc	MALTOSE-BINDING PERIPLASMIC PROTEIN, HOMEOBOX PROTEIN SIX1 CHIMERA (Escherichia coli; Homo sapiens)	4 / 8	PHE A 258 GLY A 327 LEU A 247 PRO A 159	None	1.11A	17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	4rcd	BETA-SECRETASE 1 (Homo sapiens)	4 / 8	GLY A 177 VAL A 146 LEU A 140 PRO A  91	None	1.15A	20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	5c08	1E6 TCR BETA CHAIN (Homo sapiens)	4 / 8	GLY E 218 VAL E 122 LEU E 116 PRO E 154	None	1.10A	22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	5k13	RETINOIC ACID RECEPTOR ALPHA (Homo sapiens)	4 / 8	PHE A 249 VAL A 191 LEU A 187 PRO A 247	None	1.14A	20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	5txf	PHOSPHATIDYLCHOLINE- STEROL ACYLTRANSFERASE (Homo sapiens)	4 / 8	GLY A 205 VAL A 309 LEU A 191 TRP A 198	None	0.92A	19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	5xtd	NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL (Homo sapiens)	4 / 8	PHE J  64 GLY J  66 VAL J  70 LEU J  94	None	1.04A	23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	6cph	TCR BETA CHAIN (Homo sapiens)	4 / 8	GLY E 232 VAL E 136 LEU E 130 PRO E 168	None	1.14A	17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	6en4	SPLICING FACTOR 3B SUBUNIT 3 (Homo sapiens)	4 / 8	GLY A 247 VAL A 238 LEU A 315 PRO A 245	None	1.07A	18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	1d4v	TNF-RELATED APOPTOSIS INDUCING LIGAND (Homo sapiens)	4 / 7	PHE B 275 LEU B 174 LEU B 164 LEU B 169	None	0.78A	20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	1dg6	APO2L/TNF-RELATED APOPOTIS INDUCING LIGAND (TRAIL) (Homo sapiens)	4 / 7	PHE A 275 LEU A 174 LEU A 164 LEU A 169	None	0.64A	20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	1jjx	BRAIN-TYPE FATTY ACID BINDING PROTEIN (Homo sapiens)	4 / 7	PHE A   4 LEU A  91 LEU A  66 LEU A  86	None	0.93A	22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	1ozn	RETICULON 4 RECEPTOR (Homo sapiens)	4 / 7	THR A 125 LEU A 135 LEU A 112 LEU A 110	None	0.80A	22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	1ozn	RETICULON 4 RECEPTOR (Homo sapiens)	4 / 7	THR A 173 LEU A 183 LEU A 161 LEU A 159	None	0.90A	22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	1ozn	RETICULON 4 RECEPTOR (Homo sapiens)	4 / 7	THR A 173 LEU A 185 LEU A 166 LEU A 161	None	0.89A	22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	1tow	FATTY ACID-BINDING PROTEIN, ADIPOCYTE (Homo sapiens)	4 / 7	PHE A   4 LEU A  91 LEU A  66 LEU A  86	None	0.65A	17.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	2bzg	THIOPURINE S-METHYLTRANSFERASE (Homo sapiens)	5 / 7	HIS A  52 THR A  55 GLN A 179 LEU A 217 LEU A 241	None	0.55A	71.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	2bzg	THIOPURINE S-METHYLTRANSFERASE (Homo sapiens)	4 / 7	THR A  55 GLN A 179 LEU A 181 LEU A 241	None	0.88A	71.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	2knh	PROTEIN CBFA2T1 (Homo sapiens)	4 / 7	GLN A 341 LEU A 340 LEU A 333 LEU A 337	None	0.88A	18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	2wfh	SLIT HOMOLOG 2 PROTEIN C-PRODUCT (Homo sapiens)	4 / 7	THR A 820 LEU A 830 LEU A 808 LEU A 806	None	0.91A	20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	3dxb	THIOREDOXIN N-TERMINALLY FUSED TO PUF60(UHM) (Escherichia coli; Homo sapiens)	4 / 7	PHE A 446 LEU A 424 LEU A 397 LEU A 368	None	0.80A	24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	3nr3	PMP2 PROTEIN (Homo sapiens)	4 / 7	PHE A   5 LEU A  92 LEU A  67 LEU A  87	None	0.73A	22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	3wbg	FATTY ACID-BINDING PROTEIN, HEART (Homo sapiens)	4 / 7	PHE A   4 LEU A  91 LEU A  66 LEU A  86	None	0.60A	27.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	4a6e	HYDROXYINDOLE O-METHYLTRANSFERASE (Homo sapiens)	4 / 7	PHE A 175 LEU A 342 LEU A 247 LEU A 280	None	0.61A	23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	4ifs	FACT COMPLEX SUBUNIT SSRP1 (Homo sapiens)	4 / 7	HIS A 363 GLN A 252 LEU A 208 LEU A 276	None	0.77A	23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	4nns	FATTY ACID-BINDING PROTEIN, ADIPOCYTE (Homo sapiens)	4 / 7	PHE A   4 LEU A  91 LEU A  66 LEU A  86	None	0.72A	26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	5b29	FATTY ACID-BINDING PROTEIN, HEART (Homo sapiens)	4 / 7	PHE A   4 LEU A  91 LEU A  66 LEU A  86	None	0.71A	21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	5cvo	WD REPEAT-CONTAINING PROTEIN 48 (Homo sapiens)	4 / 7	PHE A 264 GLN A 224 LEU A 226 LEU A 236	None	0.76A	18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	5fah	KALLIKREIN-7 (Homo sapiens)	4 / 7	HIS A  67 LEU A  34 LEU A  73 LEU A  40	None	0.82A	21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	5iz5	CYTOSOLIC PHOSPHOLIPASE A2 DELTA (Homo sapiens)	4 / 7	PHE B 209 LEU B 189 LEU B 244 LEU B 219	None	0.91A	15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	5k1c	WD REPEAT-CONTAINING PROTEIN 48 (Homo sapiens)	4 / 7	PHE B 264 GLN B 224 LEU B 226 LEU B 236	None	0.56A	18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	5mpo	MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT (Homo sapiens)	4 / 7	PHE A  57 LEU A  37 LEU A  73 LEU A  71	None	0.88A	27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	5ums	FACT COMPLEX SUBUNIT SSRP1 (Homo sapiens)	4 / 7	HIS A 363 GLN A 252 LEU A 208 LEU A 276	None	0.81A	17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	5xoc	THIOREDOXIN 1,FORKHEAD BOX PROTEIN H1 (Escherichia coli; Homo sapiens)	4 / 7	PHE B 313 LEU B 291 LEU B 264 LEU B 235	None	0.81A	17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	1hyn	BAND 3 ANION TRANSPORT PROTEIN (Homo sapiens)	4 / 6	ARG P 283 THR P 103 ALA P 285 ALA P 284	None	1.17A	19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	2n1b	GTP-BINDING NUCLEAR PROTEIN RAN (Homo sapiens)	4 / 6	GLU A   6 ARG A  56 ALA A   3 ALA A   2	None	1.04A	15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	2vr2	DIHYDROPYRIMIDINASE (Homo sapiens)	4 / 6	GLU A 226 THR A 307 ALA A 254 ALA A 255	None	1.16A	21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	3wo4	INTERLEUKIN-18 RECEPTOR 1 (Homo sapiens)	4 / 6	GLU B 266 THR B 299 ALA B 278 ALA B 239	None	1.25A	17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4cnt	DIHYDROPYRIMIDINASE- LIKE 3 (Homo sapiens)	4 / 6	GLU A 232 THR A 313 ALA A 260 ALA A 261	None	1.21A	22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ky9	BAND 3 ANION TRANSPORT PROTEIN (Homo sapiens)	4 / 6	ARG A 283 THR A 103 ALA A 285 ALA A 284	None	1.19A	18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4po6	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	4 / 6	PHE A 160 THR A 262 ALA A 165 ALA A 267	None	1.23A	22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4x0q	DNA POLYMERASE THETA (Homo sapiens)	4 / 6	GLU A2335 THR A2237 ALA A2477 ALA A2478	DG3  A2604 ( 4.4A) None None None	1.04A	22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4xvm	DNA POLYMERASE NU (Homo sapiens)	4 / 6	GLU A 628 THR A 567 ALA A 772 ALA A 773	None	0.93A	22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	5aga	DNA POLYMERASE THETA (Homo sapiens)	4 / 6	GLU A 830 THR A 861 ALA A 876 ALA A 875	None	1.23A	22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	5brr	TISSUE-TYPE PLASMINOGEN ACTIVATOR (Homo sapiens)	4 / 6	ARG E  60 PHE E  59 ALA E  55 ALA E  56	None	1.20A	15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	5h64	SERINE/THREONINE-PRO TEIN KINASE MTOR (Homo sapiens)	4 / 6	GLU A2388 ARG A2322 THR A2399 ALA A1428	None	1.08A	14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	5tf2	PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN (Homo sapiens)	4 / 6	PHE A  14 THR A  67 ALA A  30 ALA A  31	None	1.17A	19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	5xbk	IMPORTIN-4 (Homo sapiens)	4 / 6	PHE D 851 THR D 885 ALA D 845 ALA D 844	None	1.05A	7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_C_PM6C1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	6fuz	KINESIN LIGHT CHAIN 1,KINESIN LIGHT CHAIN 1,C-JUN-AMINO-TERMIN AL KINASE-INTERACTING PROTEIN 1 (Homo sapiens; Mus musculus)	4 / 6	GLU A 434 ARG A 475 ALA A 482 ALA A 483	None	1.22A	8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_L_PM6L1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	2a30	DEOXYCYTIDINE KINASE (Homo sapiens)	4 / 8	THR A 181 LEU A 205 ALA A  31 ALA A  32	None	0.97A	16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_L_PM6L1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	2i6b	ADENOSINE KINASE (Homo sapiens)	4 / 8	PHE A 302 LEU A 285 ALA A 326 ALA A 327	None	0.95A	20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_L_PM6L1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	3gzd	SELENOCYSTEINE LYASE (Homo sapiens)	4 / 8	ARG C 185 LEU C 152 ALA C 161 ALA C 162	None	0.99A	19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_L_PM6L1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	3gzd	SELENOCYSTEINE LYASE (Homo sapiens)	4 / 8	ARG C 185 THR C 164 LEU C 152 ALA C 161	None	0.87A	19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_L_PM6L1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	3kvo	HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 (Homo sapiens)	4 / 8	SER A  19 LEU A  50 ALA A 205 ALA A 204	NAP  A 501 (-2.7A) None NAP  A 501 (-3.3A) None	0.94A	18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_L_PM6L1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	3thz	DNA MISMATCH REPAIR PROTEIN MSH2 (Homo sapiens)	4 / 8	ARG A 308 LEU A 302 ALA A 710 ALA A 305	None	0.85A	22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_L_PM6L1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4bc5	XYLULOSE KINASE (Homo sapiens)	4 / 8	PHE A 478 LEU A  11 ALA A  91 ALA A 477	None	0.97A	22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_L_PM6L1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4cns	DIHYDROPYRIMIDINASE- LIKE 3 (Homo sapiens)	5 / 8	GLU A 232 SER A 308 THR A 313 ALA A 260 ALA A 261	None	1.46A	21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_L_PM6L1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4cnt	DIHYDROPYRIMIDINASE- LIKE 3 (Homo sapiens)	5 / 8	GLU A 232 SER A 308 THR A 313 ALA A 260 ALA A 261	None	1.41A	22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_L_PM6L1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4cyf	PANTETHEINASE (Homo sapiens)	4 / 8	SER A 265 LEU A  60 ALA A  34 ALA A  33	None	1.00A	21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_L_PM6L1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4fgu	LEGUMAIN (Homo sapiens)	4 / 8	GLU A 187 SER A 307 ALA A 209 ALA A 210	None	0.91A	20.58