POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BXC_A_P1ZA2001_1 (SERUM ALBUMIN)	1tf0	SERUM ALBUMIN (Homo sapiens)	5 / 12	TYR A 150 SER A 192 GLN A 196 HIS A 242 ALA A 258	DKA  A1003 (-4.4A) None None DKA  A1003 (-3.7A) None	0.91A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BXC_A_P1ZA2001_1 (SERUM ALBUMIN)	1tf0	SERUM ALBUMIN (Homo sapiens)	12 / 12	TYR A 150 SER A 192 GLN A 196 LYS A 199 LEU A 219 LEU A 238 HIS A 242 ARG A 257 ALA A 261 ILE A 264 ILE A 290 ALA A 291	DKA  A1003 (-4.4A) None None CIT  A2001 ( 2.7A) None DKA  A1003 (-4.3A) DKA  A1003 (-3.7A) DKA  A1003 (-4.1A) None None DKA  A1003 ( 4.5A) CIT  A2001 ( 3.9A)	0.45A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_A_P1ZA2001_1 (SERUM ALBUMIN)	2qkc	SUPEROXIDE DISMUTASE [MN] (Homo sapiens)	6 / 12	SER A 121 GLN A 143 LEU A  81 HIS A  74 ILE A  22 ALA A 164	None MN  A 199 ( 4.9A) None MN  A 199 (-3.3A) None MN  A 199 ( 4.9A)	1.15A	15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_A_P1ZA2001_1 (SERUM ALBUMIN)	2vcy	TRANS-2-ENOYL-COA REDUCTASE (Homo sapiens)	5 / 12	LEU A 261 LEU A 175 ALA A 205 ILE A 201 ALA A 199	None	1.08A	19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_A_P1ZA2001_1 (SERUM ALBUMIN)	2xa7	AP-2 COMPLEX SUBUNIT BETA (Homo sapiens)	5 / 12	LEU B 436 LEU B 465 ILE B 451 ILE B 429 ALA B 430	None	1.04A	23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_A_P1ZA2001_1 (SERUM ALBUMIN)	4bvx	EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 (Homo sapiens)	5 / 12	TYR B  59 SER B  63 LEU B  10 LEU B  14 ILE B 155	None	1.03A	15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_A_P1ZA2001_1 (SERUM ALBUMIN)	4d4z	DEOXYHYPUSINE HYDROXYLASE (Homo sapiens)	5 / 12	LEU A 107 ALA A  70 ILE A  71 ILE A  98 ALA A  97	None	0.84A	20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_A_P1ZA2001_1 (SERUM ALBUMIN)	4ric	FANCONI-ASSOCIATED NUCLEASE 1 (Homo sapiens)	5 / 12	GLN A 533 LEU A 421 LEU A 434 ALA A 440 ILE A 439	None	1.00A	22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_A_P1ZA2001_1 (SERUM ALBUMIN)	5c5x	AQUAPORIN-5 (Homo sapiens)	5 / 12	SER A 189 HIS A 173 ALA A 143 ILE A 146 ILE A  72	None	0.84A	17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_A_P1ZA2001_1 (SERUM ALBUMIN)	5k8d	COAGULATION FACTOR VIII COAGULATION FACTOR VIII,IG GAMMA-1 CHAIN C REGION (Homo sapiens)	5 / 12	SER A 109 LEU A 164 LEU B2001 HIS B1957 ILE A 173	None	1.07A	22.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BXC_B_P1ZB2001_1 (SERUM ALBUMIN)	1tf0	SERUM ALBUMIN (Homo sapiens)	9 / 9	TYR A 150 GLU A 153 LEU A 219 ARG A 222 LEU A 238 HIS A 242 ARG A 257 ALA A 261 ALA A 291	DKA  A1003 (-4.4A) None None CIT  A2001 ( 2.9A) DKA  A1003 (-4.3A) DKA  A1003 (-3.7A) DKA  A1003 (-4.1A) None CIT  A2001 ( 3.9A)	0.45A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_B_P1ZB2001_1 (SERUM ALBUMIN)	2nsm	CARBOXYPEPTIDASE N CATALYTIC CHAIN (Homo sapiens)	5 / 9	GLU A 115 LEU A   1 ARG A   4 LEU A  77 ALA A  70	None SO4  A 776 (-3.7A) SO4  A 776 (-3.8A) None None	1.06A	19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_B_P1ZB2001_1 (SERUM ALBUMIN)	2xn6	THYROXINE-BINDING GLOBULIN (Homo sapiens)	5 / 9	GLU A  71 LEU A 350 LEU A  57 ALA A  64 ALA A 308	None	1.17A	19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_B_P1ZB2001_1 (SERUM ALBUMIN)	3mpx	FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 5 (Homo sapiens)	5 / 9	TYR A1046 LEU A 967 LEU A 963 ARG A1042 ALA A 906	None	1.23A	23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_B_P1ZB2001_1 (SERUM ALBUMIN)	3nks	PROTOPORPHYRINOGEN OXIDASE (Homo sapiens)	5 / 9	GLU A 461 LEU A 236 LEU A  74 HIS A  20 ALA A  69	None	1.40A	22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_B_P1ZB2001_1 (SERUM ALBUMIN)	3op0	SIGNAL TRANSDUCTION PROTEIN CBL-C (Homo sapiens)	5 / 9	GLU A  13 LEU A  55 LEU A  80 ALA A  85 ALA A  17	None	1.36A	18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_B_P1ZB2001_1 (SERUM ALBUMIN)	3x1o	ROQUIN-1 (Homo sapiens)	5 / 9	GLU A 293 LEU A 179 LEU A 183 ARG A 190 ALA A 294	None	1.50A	16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_B_P1ZB2001_1 (SERUM ALBUMIN)	4c6o	CAD PROTEIN (Homo sapiens)	5 / 9	GLU A1592 LEU A1650 LEU A1664 HIS A1642 ARG A1617	None	1.48A	20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_B_P1ZB2001_1 (SERUM ALBUMIN)	4o9r	SMOOTHENED HOMOLOG/SOLUBLE CYTOCHROME B562 CHIMERIC PROTEIN (Escherichia coli; Homo sapiens)	5 / 9	GLU A1018 LEU A1068 LEU A1010 ALA A1029 ALA A1091	None	1.33A	21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_B_P1ZB2001_1 (SERUM ALBUMIN)	4on3	SORTING NEXIN-10 (Homo sapiens)	5 / 9	GLU A   9 LEU A 121 LEU A 106 ALA A 109 ALA A  42	None NA  A 315 (-4.5A) None None None	1.19A	15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	1md7	C1R COMPLEMENT SERINE PROTEASE (Homo sapiens)	5 / 12	LEU A 561 LEU A 475 LEU A 543 ALA A 542 ILE A 541	None	1.21A	20.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	1tf0	SERUM ALBUMIN (Homo sapiens)	10 / 12	PHE A 211 TRP A 214 LEU A 219 PHE A 223 LEU A 238 HIS A 242 LEU A 260 ALA A 261 ILE A 264 ALA A 291	None None None None DKA  A1003 (-4.3A) DKA  A1003 (-3.7A) None None None CIT  A2001 ( 3.9A)	0.44A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	1tf0	SERUM ALBUMIN (Homo sapiens)	9 / 12	PHE A 211 TRP A 214 LEU A 219 PHE A 223 LEU A 238 HIS A 242 LEU A 260 SER A 287 ALA A 291	None None None None DKA  A1003 (-4.3A) DKA  A1003 (-3.7A) None None CIT  A2001 ( 3.9A)	0.62A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	2v0s	LR1 (Homo sapiens)	5 / 12	LEU A  77 LEU A  54 LEU A  18 ILE A  15 ALA A  28	None	1.21A	17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	2xdv	MYC-INDUCED NUCLEAR ANTIGEN (Homo sapiens)	5 / 12	LEU A 198 PHE A 234 LEU A 226 ILE A 187 ALA A 242	None None None None OGA  A 601 ( 4.2A)	1.18A	22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	2ybu	ACIDIC MAMMALIAN CHITINASE (Homo sapiens)	5 / 12	PHE A 119 LEU A 127 LEU A  94 ALA A  95 ILE A  96	None	1.12A	20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	2ygs	APOPTOTIC PROTEASE ACTIVATING FACTOR 1 (Homo sapiens)	5 / 12	LEU A  87 LEU A  75 ALA A  53 ILE A  57 ALA A  15	None	1.17A	8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	3bpt	3-HYDROXYISOBUTYRYL- COA HYDROLASE (Homo sapiens)	5 / 12	PHE A 117 LEU A 124 LEU A  60 LEU A  51 ILE A  49	None	1.21A	19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	3gxu	EPHRIN TYPE-A RECEPTOR 4 (Homo sapiens)	5 / 12	PHE A 153 LEU A  96 PHE A  94 LEU A 155 SER A 168	None	1.21A	14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	3mos	TRANSKETOLASE (Homo sapiens)	5 / 12	TRP A 211 PHE A 228 LEU A 182 ALA A  44 ILE A  47	None	1.13A	22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	3tac	LIPRIN-ALPHA-2 (Homo sapiens)	5 / 12	LEU B1063 LEU B1054 LEU B1051 ALA B1048 ILE B1024	None	1.24A	18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	3tad	LIPRIN-ALPHA-2 (Homo sapiens)	5 / 12	LEU A1063 LEU A1054 LEU A1051 ALA A1048 ILE A1024	None	1.25A	18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	3u12	USP37 PROTEIN (Homo sapiens)	5 / 12	LEU A  38 LEU A  74 LEU A  72 ALA A  92 ILE A   6	None None None None UNX  A1019 ( 4.3A)	1.09A	11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	1jmy	BILE-SALT-ACTIVATED LIPASE (Homo sapiens)	5 / 12	LEU A   3 LEU A  98 ILE A 137 ILE A 178 ALA A 179	None	0.85A	22.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	1tf0	SERUM ALBUMIN (Homo sapiens)	6 / 12	LEU A 219 ARG A 222 PHE A 223 LEU A 238 HIS A 242 ILE A 264	None CIT  A2001 ( 2.9A) None DKA  A1003 (-4.3A) DKA  A1003 (-3.7A) None	1.45A	99.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	1tf0	SERUM ALBUMIN (Homo sapiens)	10 / 12	LYS A 199 LEU A 219 ARG A 222 PHE A 223 LEU A 238 HIS A 242 ILE A 264 SER A 287 ILE A 290 ALA A 291	CIT  A2001 ( 2.7A) None CIT  A2001 ( 2.9A) None DKA  A1003 (-4.3A) DKA  A1003 (-3.7A) None None DKA  A1003 ( 4.5A) CIT  A2001 ( 3.9A)	0.82A	99.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	1tf0	SERUM ALBUMIN (Homo sapiens)	11 / 12	LYS A 199 LEU A 219 PHE A 223 LEU A 238 HIS A 242 ARG A 257 LEU A 260 ILE A 264 SER A 287 ILE A 290 ALA A 291	CIT  A2001 ( 2.7A) None None DKA  A1003 (-4.3A) DKA  A1003 (-3.7A) DKA  A1003 (-4.1A) None None None DKA  A1003 ( 4.5A) CIT  A2001 ( 3.9A)	0.83A	99.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	2a9j	BISPHOSPHOGLYCERATE MUTASE (Homo sapiens)	5 / 12	LEU A 199 LEU A 195 ILE A 185 ILE A 173 ALA A 174	None	0.99A	18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	2dh3	4F2 CELL-SURFACE ANTIGEN HEAVY CHAIN (Homo sapiens)	5 / 12	LEU A 192 PHE A 189 LEU A 143 LEU A 129 ILE A 163	None	0.87A	22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	2xa7	AP-2 COMPLEX SUBUNIT BETA (Homo sapiens)	5 / 12	LEU B 436 LEU B 465 ILE B 451 ILE B 429 ALA B 430	None	0.97A	23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	2z63	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	LEU A  83 LEU A  85 LEU A  66 ILE A  48 ALA A  97	None	1.01A	21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	2z7x	TOLL-LIKE RECEPTOR 1, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	6 / 12	LEU B 400 LEU B 425 LEU B 428 ILE B 405 ILE B 390 ALA B 391	None	1.46A	23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	3p8c	NCK-ASSOCIATED PROTEIN 1 (Homo sapiens)	5 / 12	LEU B 999 LEU B1043 ILE B 910 SER B 860 ALA B 864	None	1.04A	20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	4ay1	CHITINASE-3-LIKE PROTEIN 2 (Homo sapiens)	6 / 12	LEU A 158 PHE A 111 LEU A 162 LEU A 140 ILE A 101 ALA A 182	None	1.44A	20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	4pj6	LEUCYL-CYSTINYL AMINOPEPTIDASE (Homo sapiens)	5 / 12	LEU A1025 PHE A 750 LEU A 787 LEU A 779 ILE A 775	None	1.02A	21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	5c7m	E3 UBIQUITIN-PROTEIN LIGASE ITCHY HOMOLOG (Homo sapiens)	6 / 12	LEU A 886 PHE A 815 LEU A 877 LEU A 875 ILE A 894 ALA A 893	None	1.45A	22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	5ed1	DOUBLE-STRANDED RNA-SPECIFIC EDITASE 1 (Homo sapiens)	5 / 12	LEU A 556 ILE A 545 SER A 517 ILE A 520 ALA A 521	None	0.96A	20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	5hdh	TOLL-LIKE RECEPTOR 8 (Homo sapiens)	5 / 12	LEU A 413 PHE A 417 LEU A 382 LEU A 401 ILE A 399	None	1.00A	21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	5vil	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (Homo sapiens)	6 / 12	LEU A 938 PHE A 937 LEU A 788 LEU A 867 ILE A 871 ILE A 915	None	1.32A	8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	6eti	ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 2 (Homo sapiens)	5 / 12	LEU A  75 PHE A 253 LEU A 228 ILE A 249 ILE A 242	None	0.95A	8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_P1ZA2002_1 (SERUM ALBUMIN)	6ez8	HUNTINGTIN (Homo sapiens)	5 / 12	LEU A1614 LEU A1630 LEU A1581 ILE A1575 ILE A1606	None	1.04A	6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	1tff	UBIQUITIN THIOLESTERASE PROTEIN OTUB2 (Homo sapiens)	5 / 10	TYR A  60 PHE A 102 LEU A  64 VAL A 109 LEU A  61	None	1.27A	22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	1uch	UBIQUITIN C-TERMINAL HYDROLASE UCH-L3 (Homo sapiens)	5 / 10	ILE A 101 TYR A 137 TYR A 141 LEU A  23 LEU A  25	None	1.50A	22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	2q9v	MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 10	ILE A 870 MET A 908 LEU A 844 VAL A 917 LEU A 919	None	1.26A	14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	2w5h	SERINE/THREONINE-PRO TEIN KINASE NEK2 (Homo sapiens)	5 / 10	ILE A  98 PHE A 112 TYR A 182 VAL A 155 LEU A 149	None	1.45A	21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	2z65	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 10	ILE A  93 PHE A 144 LEU A 107 VAL A 132 LEU A 131	None	1.44A	22.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	2zb4	PROSTAGLANDIN REDUCTASE 2 (Homo sapiens)	7 / 10	TYR A  51 ILE A  65 TYR A 259 TYR A 265 LEU A 288 VAL A 289 LEU A 290	5OP  A 600 (-3.4A) 5OP  A 600 ( 4.6A) NAP  A 500 (-4.4A) None NAP  A 500 (-4.7A) NAP  A 500 ( 3.6A) 5OP  A 600 (-3.7A)	0.87A	97.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	3bcz	PROTEIN MEMO1 (Homo sapiens)	5 / 10	ILE A 154 PHE A 173 TYR A  96 VAL A 158 LEU A  77	None	1.41A	20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	3fxi	TOLL-LIKE RECEPTOR 4 (Homo sapiens)	5 / 10	ILE A  93 PHE A 144 LEU A 107 VAL A 132 LEU A 131	None	1.40A	20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	3l6a	EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2 (Homo sapiens)	5 / 10	ILE A 114 PHE A 137 MET A 164 LEU A 153 LEU A 141	None	1.12A	21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	3se4	INTERFERON OMEGA-1 (Homo sapiens)	5 / 10	ILE B 150 PHE B  40 MET B  44 VAL B  58 LEU B 122	None	1.37A	19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	4dou	ADIPONECTIN (Homo sapiens)	5 / 10	PHE A 273 TYR A 159 TYR A 300 LEU A 316 LEU A 354	None	1.40A	20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	6bbp	CYTOHESIN-3,ADP-RIBO SYLATION FACTOR 6 (Homo sapiens; Mus musculus)	5 / 10	ILE A 225 PHE A 218 LEU A 145 VAL A 146 LEU A 239	None	1.35A	12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	6cd8	GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG (Homo sapiens)	5 / 10	ILE A 260 PHE A 128 LEU A 155 VAL A 148 LEU A 145	None None None UNX  A 303 ( 4.6A) None	1.42A	13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1352_1 (PROSTAGLANDIN REDUCTASE 2)	2bfe	2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT (Homo sapiens)	4 / 7	TYR A 121 TYR A 190 LEU A 103 ASN A 105	None	1.19A	22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1352_1 (PROSTAGLANDIN REDUCTASE 2)	4fzd	SERINE/THREONINE-PRO TEIN KINASE MST4 (Homo sapiens)	4 / 7	TYR B 101 LEU B 102 LYS B 159 TYR B  86	GOL  B1000 (-4.0A) GOL  B1000 (-4.7A) None None	1.42A	21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1352_1 (PROSTAGLANDIN REDUCTASE 2)	4n49	CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1 (Homo sapiens)	4 / 7	LEU A 479 ASN A 478 TYR A 459 LYS A 381	None	1.45A	20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1352_1 (PROSTAGLANDIN REDUCTASE 2)	4red	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (Homo sapiens)	4 / 7	TYR A 238 TYR A 234 LEU A 239 ASN A 240	None	1.47A	19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1352_1 (PROSTAGLANDIN REDUCTASE 2)	4wjl	INACTIVE DIPEPTIDYL PEPTIDASE 10 (Homo sapiens)	4 / 7	TYR A 282 ASN A 760 TYR A 683 LYS A 650	None	1.42A	20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1352_1 (PROSTAGLANDIN REDUCTASE 2)	6dd3	CYTOSOLIC PURINE 5'-NUCLEOTIDASE (Homo sapiens)	4 / 7	TYR A 262 TYR A  60 LEU A 263 TYR A 255	None	1.40A	12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1353_1 (PROSTAGLANDIN REDUCTASE 2)	1xap	RETINOIC ACID RECEPTOR BETA (Homo sapiens)	5 / 9	PHE A 192 GLU A 190 GLY A 320 GLU A 182 ILE A 184	None	1.34A	21.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W98_A_P1ZA1353_1 (PROSTAGLANDIN REDUCTASE 2)	2zb4	PROSTAGLANDIN REDUCTASE 2 (Homo sapiens)	5 / 9	THR A  97 GLU A 115 VAL A 117 GLY A 134 ILE A 300	None	0.61A	97.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W98_A_P1ZA1353_1 (PROSTAGLANDIN REDUCTASE 2)	2zb4	PROSTAGLANDIN REDUCTASE 2 (Homo sapiens)	5 / 9	THR A  97 VAL A 117 GLY A 134 PHE A 296 ILE A 300	None	0.73A	97.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1353_1 (PROSTAGLANDIN REDUCTASE 2)	3k9m	CATHEPSIN B (Homo sapiens)	5 / 9	PHE A 174 GLU A 245 VAL A 247 GLY A  33 GLU A  78	None	1.49A	21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1353_1 (PROSTAGLANDIN REDUCTASE 2)	4amt	RENIN (Homo sapiens)	5 / 9	GLU A 156 VAL A 131 GLY A 152 PHE A 134 GLU A 121	None	1.39A	23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	1i4e	CASPASE-8 (Homo sapiens)	4 / 8	ILE B2311 PHE B2476 LEU B2425 LEU B2429	None	0.73A	20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	1je6	MHC CLASS I CHAIN-RELATED PROTEIN (Homo sapiens)	4 / 8	PHE A 117 TYR A 157 LEU A  73 LEU A  90	None	0.87A	22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	1m9i	ANNEXIN VI (Homo sapiens)	4 / 8	ILE A 461 TYR A 477 LEU A 489 LEU A 501	None	0.90A	21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	2bzl	TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 14 (Homo sapiens)	4 / 8	TYR A 913 ILE A 916 LEU A1133 VAL A1130	None	0.89A	21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	2gf1	INSULIN-LIKE GROWTH FACTOR I (Homo sapiens)	4 / 8	TYR A  31 LEU A  14 VAL A  11 LEU A  10	None	0.88A	13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	2y9t	TUMOR PROTEIN 63 (Homo sapiens)	4 / 8	ILE A 601 PHE A 565 LEU A 556 LEU A 553	None	0.90A	11.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	2zb4	PROSTAGLANDIN REDUCTASE 2 (Homo sapiens)	5 / 8	TYR A  51 ILE A  65 TYR A 259 TYR A 265 LEU A 288	5OP  A 600 (-3.4A) 5OP  A 600 ( 4.6A) NAP  A 500 (-4.4A) None NAP  A 500 (-4.7A)	0.61A	97.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	2zb4	PROSTAGLANDIN REDUCTASE 2 (Homo sapiens)	6 / 8	TYR A  51 TYR A 259 TYR A 265 LEU A 288 VAL A 289 LEU A 290	5OP  A 600 (-3.4A) NAP  A 500 (-4.4A) None NAP  A 500 (-4.7A) NAP  A 500 ( 3.6A) 5OP  A 600 (-3.7A)	0.52A	97.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	3naf	CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1,CALCIUM-ACTI VATED POTASSIUM CHANNEL SUBUNIT ALPHA-1,CALCIUM-ACTI VATED POTASSIUM CHANNEL SUBUNIT ALPHA-1 (Homo sapiens)	4 / 8	ILE A 598 TYR A 996 LEU A1052 VAL A 977	None	0.88A	18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	3nmz	APC VARIANT PROTEIN (Homo sapiens)	4 / 8	ILE A 357 LEU A 407 VAL A 406 LEU A 410	None	0.82A	21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	3vut	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 (Homo sapiens)	4 / 8	ILE A 367 TYR A 358 LEU A 293 LEU A 297	None	0.88A	21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	4mk0	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	4 / 8	TYR A  86 ILE A 153 PHE A  59 TYR A 112	None	0.83A	19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	4wk0	INTEGRIN BETA-1 (Homo sapiens)	4 / 8	ILE B 375 PHE B 111 LEU B 438 LEU B 101	None	0.63A	23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	5d68	KREV INTERACTION TRAPPED PROTEIN 1 (Homo sapiens)	4 / 8	PHE A 708 TYR A 683 VAL A 660 LEU A 669	None	0.80A	21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1356_1 (PROSTAGLANDIN REDUCTASE 2)	5i6v	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 (Homo sapiens)	4 / 8	TYR A 515 ILE A 226 VAL A 471 LEU A 475	None	0.83A	20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1357_1 (PROSTAGLANDIN REDUCTASE 2)	1r47	ALPHA-GALACTOSIDASE A (Homo sapiens)	4 / 6	TYR A  86 LEU A 300 ASN A 298 ASP A 234	None	1.24A	21.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W98_B_P1ZB1357_1 (PROSTAGLANDIN REDUCTASE 2)	2zb4	PROSTAGLANDIN REDUCTASE 2 (Homo sapiens)	4 / 6	LEU A 288 ASN A 291 LYS A 293 ASP A 294	NAP  A 500 (-4.7A) None None None	0.57A	97.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1357_1 (PROSTAGLANDIN REDUCTASE 2)	3gv5	DNA POLYMERASE IOTA (Homo sapiens)	4 / 6	LEU B 205 ASN B 202 LYS B  28 ASP B 131	None	1.39A	22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1357_1 (PROSTAGLANDIN REDUCTASE 2)	3rru	TOM1L1 PROTEIN (Homo sapiens)	4 / 6	TYR A 143 LEU A 120 ASN A 121 ASP A  77	None	1.38A	18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1357_1 (PROSTAGLANDIN REDUCTASE 2)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	4 / 6	TYR A 189 LEU A 215 ASN A 219 ASP A 320	None None None BHF  A 602 (-3.7A)	1.26A	21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1357_1 (PROSTAGLANDIN REDUCTASE 2)	6cet	GATOR COMPLEX PROTEIN DEPDC5 (Homo sapiens)	4 / 6	LYS D 411 LEU D 271 ASN D 197 ASP D 189	None	1.45A	11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1358_1 (PROSTAGLANDIN REDUCTASE 2)	2a98	INOSITOL 1,4,5-TRISPHOSPHATE 3-KINASE C (Homo sapiens)	4 / 6	ASP A 484 TYR A 595 PHE A 552 LEU A 581	None	1.04A	20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1358_1 (PROSTAGLANDIN REDUCTASE 2)	2vd5	DMPK PROTEIN (Homo sapiens)	4 / 6	ASP A 204 TYR A 151 PHE A 354 LEU A 159	None BI8  A1417 (-4.9A) None None	1.09A	21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1358_1 (PROSTAGLANDIN REDUCTASE 2)	2vsv	RHOPHILIN-2 (Homo sapiens)	4 / 6	ASP A 556 TYR A 557 PHE A 519 LEU A 578	None	1.17A	14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1358_1 (PROSTAGLANDIN REDUCTASE 2)	2xrc	HUMAN COMPLEMENT FACTOR I (Homo sapiens)	4 / 6	ASP A 411 TYR A 408 TYR A 486 TYR A 547	None	1.23A	20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1358_1 (PROSTAGLANDIN REDUCTASE 2)	3b3l	KETOHEXOKINASE (Homo sapiens)	4 / 6	ASP A 231 TYR A 212 PHE A 201 LEU A 211	None	1.15A	21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1358_1 (PROSTAGLANDIN REDUCTASE 2)	3pta	DNA (CYTOSINE-5)-METHYLT RANSFERASE 1 (Homo sapiens)	4 / 6	ASP A 937 TYR A 940 TYR A 933 LEU A 941	None	1.19A	16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1358_1 (PROSTAGLANDIN REDUCTASE 2)	5fhz	ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3 (Homo sapiens)	4 / 6	TYR A 492 PHE A 144 TYR A 143 LEU A 494	None	1.23A	21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1358_1 (PROSTAGLANDIN REDUCTASE 2)	5tte	E3 UBIQUITIN-PROTEIN LIGASE ARIH1 (Homo sapiens)	4 / 6	TYR B 474 TYR B 481 TYR B 547 LEU B 482	None	1.14A	19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1358_1 (PROSTAGLANDIN REDUCTASE 2)	5udh	E3 UBIQUITIN-PROTEIN LIGASE ARIH1 (Homo sapiens)	4 / 6	TYR A 474 TYR A 481 TYR A 547 LEU A 482	None	1.20A	20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1358_1 (PROSTAGLANDIN REDUCTASE 2)	6dd3	CYTOSOLIC PURINE 5'-NUCLEOTIDASE (Homo sapiens)	4 / 6	ASP A 351 TYR A  55 PHE A  51 LEU A 232	PO4  A 601 ( 4.6A) None None None	1.23A	12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	1a4i	METHYLENETETRAHYDROF OLATE DEHYDROGENASE / METHENYLTETRAHYDROFO LATE CYCLOHYDROLASE (Homo sapiens)	4 / 6	THR A 111 GLU A 112 MET A  82 ILE A 118	None	1.20A	21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	1dgf	CATALASE (Homo sapiens)	4 / 6	THR A 434 GLU A 191 MET A 350 ILE A 159	None None HEM  A3000 (-3.7A) None	1.42A	19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	1di4	LYSOZYME C (Homo sapiens)	4 / 6	THR A  11 GLU A   7 MET A  29 ILE A  56	None	0.99A	18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	1fnf	FIBRONECTIN (Homo sapiens)	4 / 6	THR A1301 GLU A1302 MET A1252 PHE A1244	None	1.41A	21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	1nvp	TRANSCRIPTION INITIATION FACTOR IIA BETA CHAIN (Homo sapiens)	4 / 6	MET C 358 LYS C 369 PHE C 367 ILE C 366	None	1.41A	13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	2b4x	ANTITHROMBIN-III (Homo sapiens)	4 / 6	THR I 419 GLU I 414 PHE I 221 ILE I 219	None	1.37A	21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	2h57	ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6 (Homo sapiens)	4 / 6	THR A  31 GLU A  56 PHE A  53 ILE A  51	MG  A 202 ( 3.0A) None None None	1.44A	20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	2iip	NICOTINAMIDE N-METHYLTRANSFERASE (Homo sapiens)	4 / 6	GLU A  76 LYS A  55 PHE A  78 ILE A  81	None	1.14A	21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	2lkk	FATTY ACID-BINDING PROTEIN, LIVER (Homo sapiens)	4 / 6	GLU A  13 MET A  19 PHE A 120 ILE A 118	None OLA  A 128 (-3.5A) OLA  A 128 ( 4.3A) None	1.34A	18.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	2zb4	PROSTAGLANDIN REDUCTASE 2 (Homo sapiens)	5 / 6	THR A  97 GLU A 115 LYS A 293 PHE A 296 ILE A 300	None	0.64A	97.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	3ba0	MACROPHAGE METALLOELASTASE (Homo sapiens)	4 / 6	THR A 292 GLU A 337 PHE A 345 ILE A 355	None	1.30A	21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	3lms	CARBOXYPEPTIDASE B2 (Homo sapiens)	4 / 6	GLU A 292 MET A 195 PHE A  78 ILE A  74	None	1.18A	19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	3thz	DNA MISMATCH REPAIR PROTEIN MSH2 (Homo sapiens)	4 / 6	THR A 456 GLU A 452 PHE A 450 ILE A 584	None	1.27A	17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	3zus	BOTULINUM NEUROTOXIN TYPE A, SYNAPTOSOMAL-ASSOCIA TED PROTEIN 23 (Clostridium botulinum; Homo sapiens)	4 / 6	GLU A 197 MET A 831 LYS A 781 ILE A 827	None	1.26A	17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	4igg	CATENIN ALPHA-1 (Homo sapiens)	4 / 6	THR A 727 GLU A 725 MET A 826 ILE A 749	None	1.33A	17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	4igg	CATENIN ALPHA-1 (Homo sapiens)	4 / 6	THR A 727 MET A 826 LYS A 717 ILE A 749	None	1.35A	17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	4lk3	UDP-GLUCURONIC ACID DECARBOXYLASE 1 (Homo sapiens)	4 / 6	GLU A 204 LYS A 361 PHE A 259 ILE A 258	None None None NAD  A 501 (-3.9A)	1.03A	21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	4qn9	N-ACYL-PHOSPHATIDYLE THANOLAMINE-HYDROLYZ ING PHOSPHOLIPASE D (Homo sapiens)	4 / 6	THR A 128 GLU A 138 PHE A 144 ILE A 178	None	1.44A	18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	5fur	TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 (Homo sapiens)	4 / 6	MET C 358 LYS C 369 PHE C 367 ILE C 366	None	1.39A	9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	5hvf	CARBOXYPEPTIDASE B2 (Homo sapiens)	4 / 6	GLU A 385 MET A 287 PHE A 168 ILE A 164	None	1.20A	22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	5n47	FIBRONECTIN (Homo sapiens)	4 / 6	THR B1423 GLU B1424 MET B1374 PHE B1366	None	1.42A	13.74