POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.


DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZWP_A_NIMA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
2jis CYSTEINE SULFINIC
ACID DECARBOXYLASE
(Homo
sapiens)
4 / 5LEU A  93
GLY A 246
ASP A 273
LYS A 305
None
None
PLP  A1494 (-2.7A)
PLP  A1494 (-1.4A)
1.49A13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZWP_A_NIMA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
3k9b LIVER
CARBOXYLESTERASE 1
(Homo
sapiens)
4 / 5LEU A1144
GLY A1176
TRP A1189
ASP A1193
None
1.43A11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
2a1x PHYTANOYL-COA
DIOXYGENASE
(Homo
sapiens)
4 / 5LEU A 206
ALA A 277
ILE A 159
SER A 279
None
AKG  A 451 ( 4.5A)
AKG  A 451 (-3.5A)
None
1.13A18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
2ch6 N-ACETYL-D-GLUCOSAMI
NE KINASE
(Homo
sapiens)
4 / 5LEU A  19
ALA A 316
SER A  70
LYS A  57
None
0.74A15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
2kij COPPER-TRANSPORTING
ATPASE 1
(Homo
sapiens)
4 / 5LEU A   7
ALA A  86
ILE A  85
SER A  88
None
0.98A17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
2p0w HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Homo
sapiens)
4 / 5LEU A 215
ALA A  80
ILE A  79
SER A  82
None
1.08A18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
2ys1 DYNAMIN-2
(Homo
sapiens)
4 / 5LEU A  38
ALA A 111
ILE A   9
SER A 107
None
1.10A19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
3krm INSULIN-LIKE GROWTH
FACTOR 2
MRNA-BINDING PROTEIN
1
(Homo
sapiens)
4 / 5LEU A 513
ALA A 519
ILE A 539
SER A 546
None
1.15A19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
3woy CLIP-ASSOCIATING
PROTEIN 2
(Homo
sapiens)
4 / 5LEU A  88
ALA A 122
ILE A  80
SER A 118
None
1.11A15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
4y7i MYOTUBULARIN-RELATED
PROTEIN 8
(Homo
sapiens)
4 / 5LEU A 335
ALA A 201
ILE A 202
SER A 192
None
1.04A15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
5ed1 DOUBLE-STRANDED
RNA-SPECIFIC EDITASE
1
(Homo
sapiens)
4 / 5LEU A 547
ALA A 324
ILE A 584
SER A 328
None
1.10A15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens)
4 / 4GLU A 120
GLY A 122
THR A 176
GLU A 174
None
1.20A17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
2bo9 HUMAN LATEXIN
(Homo
sapiens)
4 / 4GLU B  60
GLY B  96
THR B  95
GLU B  94
None
0.98A21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
2h5j CASPASE-3, P17
SUBUNIT
(Homo
sapiens)
4 / 4GLU A 123
GLY A 165
THR A 166
GLU A 167
None
0.75A18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
2pvs PANCREATIC
LIPASE-RELATED
PROTEIN 2
(Homo
sapiens)
4 / 4GLU A 426
GLY A 428
THR A 429
GLU A 430
None
0.93A20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
2q4q UPF0366 PROTEIN
C11ORF67
(Homo
sapiens)
4 / 4GLU A  40
GLY A  42
THR A  43
GLU A  44
None
0.77A16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
2xxz LYSINE-SPECIFIC
DEMETHYLASE 6B
(Homo
sapiens)
4 / 4GLU A1389
GLY A1464
THR A1465
GLU A1412
NI  A2494 ( 2.5A)
None
None
None
1.21A20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
3fed GLUTAMATE
CARBOXYPEPTIDASE III
(Homo
sapiens)
4 / 4GLU A 414
GLY A 420
THR A 422
GLU A 423
BIX  A   1 ( 2.7A)
None
None
CA  A1755 (-2.2A)
1.01A20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
3lpp SUCRASE-ISOMALTASE
(Homo
sapiens)
4 / 4GLU A 252
GLY A 256
THR A 254
GLU A 690
None
1.18A17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
4k0v TEK TYROSINE KINASE
VARIANT
(Homo
sapiens)
4 / 4GLU A 235
GLY A 238
THR A 237
GLU A 239
None
1.10A21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
4ps0 CASPASE-3
(Homo
sapiens)
4 / 4GLU A 123
GLY A 165
THR A 166
GLU A 167
None
0.65A19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
4yu9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE
(Homo
sapiens)
4 / 4GLU A 117
GLY A 116
THR A 113
GLU A 115
None
1.13A21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
4zgi TRAF-INTERACTING
PROTEIN WITH FHA
DOMAIN-CONTAINING
PROTEIN A
(Homo
sapiens)
4 / 4GLU A 129
GLY A 131
THR A  12
GLU A  11
None
1.26A17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
5eu6 HUMAN TCR HEAVY
CHAIN
(Homo
sapiens)
4 / 4GLU E  15
GLY E  17
THR E  83
GLU E  84
None
1.25A20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
5fxv HISTONE DEMETHYLASE
UTY
(Homo
sapiens)
4 / 4GLU A1095
GLY A1170
THR A1171
GLU A1118
MN  A2346 (-2.7A)
None
EDO  A2353 ( 4.9A)
None
1.12A22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
6c90 EXOSOME RNA HELICASE
MTR4,EXOSOME RNA
HELICASE MTR4
(Homo
sapiens)
4 / 4GLU A1001
GLY A1026
THR A1028
GLU A1025
None
0.95A14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
6d6q EXOSOME RNA HELICASE
MTR4
(Homo
sapiens)
4 / 4GLU M1001
GLY M1026
THR M1028
GLU M1025
None
0.97A15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
1orf GRANZYME A
(Homo
sapiens)
5 / 12LEU A 155
TYR A  29
GLY A  44
ALA A  43
SER A 197
None
1.20A19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
2gk9 PHOSPHATIDYLINOSITOL
-4-PHOSPHATE
5-KINASE, TYPE II,
GAMMA
(Homo
sapiens)
5 / 12LEU A 126
TYR A 189
GLY A  54
ALA A  56
SER A  58
None
1.00A21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
2hpa PROTEIN (ACID
PHOSPHATASE)
(Homo
sapiens)
5 / 12LEU A1203
PHE A1155
ILE A1156
SER A1163
LEU A1165
None
1.22A22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
3fb2 SPECTRIN ALPHA
CHAIN, BRAIN
SPECTRIN
(Homo
sapiens)
5 / 12HIS A1451
LEU A1367
GLY A1373
ALA A1374
LEU A1378
None
1.14A18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
3k2i ACYL-COENZYME A
THIOESTERASE 4
(Homo
sapiens)
5 / 12LEU A 229
ILE A 231
GLY A 234
ALA A 235
LEU A 239
None
1.14A21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
3tw8 DENN
DOMAIN-CONTAINING
PROTEIN 1B
(Homo
sapiens)
5 / 12LEU A 186
ILE A 210
GLY A 212
ALA A 214
LEU A 217
None
1.09A21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
4asi ACETYL-COA
CARBOXYLASE 1
(Homo
sapiens)
5 / 12LEU A1737
GLY A1842
ALA A1841
SER A1844
LEU A1868
None
1.18A21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
4ot9 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT
(Homo
sapiens)
5 / 12HIS A 493
LEU A 555
GLY A 550
ALA A 551
LEU A 547
None
1.20A21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5c5x AQUAPORIN-5
(Homo
sapiens)
5 / 12LEU A  22
ILE A  99
GLY A 103
ALA A 102
LEU A  29
None
1.01A19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5foe GDP-FUCOSE PROTEIN
O-FUCOSYLTRANSFERASE
2,THROMBOSPONDIN-1
(Caenorhabditis
elegans;
Homo
sapiens)
5 / 12TRP A  85
PHE A 104
ILE A 364
GLY A 360
ALA A 363
None
None
None
EDO  A1429 ( 3.9A)
GDP  A1428 (-3.8A)
1.26A19.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5ikr PROSTAGLANDIN G/H
SYNTHASE 2
(Homo
sapiens)
10 / 12HIS A  90
ARG A 120
LEU A 352
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
SER A 530
LEU A 531
None
ID8  A 601 ( 4.4A)
ID8  A 601 (-4.1A)
ID8  A 601 (-3.8A)
ID8  A 601 ( 3.5A)
COH  A 602 (-4.5A)
ID8  A 601 (-3.5A)
ID8  A 601 (-3.5A)
ID8  A 601 (-2.7A)
ID8  A 601 (-3.5A)
0.63A63.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5ikr PROSTAGLANDIN G/H
SYNTHASE 2
(Homo
sapiens)
9 / 12HIS A  90
ARG A 120
LEU A 352
TYR A 385
TRP A 387
PHE A 518
GLY A 526
SER A 530
LEU A 531
None
ID8  A 601 ( 4.4A)
ID8  A 601 (-4.1A)
ID8  A 601 ( 3.5A)
COH  A 602 (-4.5A)
None
ID8  A 601 (-3.5A)
ID8  A 601 (-2.7A)
ID8  A 601 (-3.5A)
0.82A63.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5jo5 10E8 GLV
(Homo
sapiens)
5 / 12PHE L  62
ILE L  75
GLY L  77
ALA L  78
LEU L  15
None
1.16A17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5l6q H5AL
(Homo
sapiens)
5 / 12PHE A  60
ILE A  73
GLY A  75
ALA A  76
LEU A  13
None
1.21A12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
1dee IGM RF 2A2
(Homo
sapiens)
3 / 3VAL B 691
SER B 672
LEU B 693
None
0.77A16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
1o5e SERINE PROTEASE
HEPSIN
(Homo
sapiens)
3 / 3VAL L  40
SER L  44
LEU L  31
None
0.76A12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens)
3 / 3VAL A  65
SER A  69
LEU A 107
None
0.74A20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
2f28 SIALIDASE 2
(Homo
sapiens)
3 / 3VAL A 175
SER A 173
LEU A 198
None
0.72A21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
2gy5 ANGIOPOIETIN-1
RECEPTOR
(Homo
sapiens)
3 / 3VAL A 188
SER A 190
LEU A  64
None
0.73A19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
2h32 IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens)
3 / 3VAL H 190
SER H 171
LEU H 192
None
0.47A16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
2y1h PUTATIVE
DEOXYRIBONUCLEASE
TATDN3
(Homo
sapiens)
3 / 3VAL A 146
SER A 148
LEU A 169
None
0.60A20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens)
3 / 3VAL A 117
SER A 121
LEU A  80
None
0.64A20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens)
3 / 3VAL A 118
SER A 122
LEU A 243
None
0.53A21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
3fhc NUCLEAR PORE COMPLEX
PROTEIN NUP214
(Homo
sapiens)
3 / 3VAL A 152
SER A 118
LEU A 169
None
0.76A20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
3lgg ADENOSINE DEAMINASE
CECR1
(Homo
sapiens)
3 / 3VAL A 368
SER A 372
LEU A 362
None
0.77A20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
3rmv GLYCOGENIN-1
(Homo
sapiens)
3 / 3VAL A  21
SER A  25
LEU A 106
None
0.63A18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
3t2n SERINE PROTEASE
HEPSIN
(Homo
sapiens)
3 / 3VAL A  85
SER A  89
LEU A  76
None
0.69A21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
1hyn BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens)
5 / 12HIS P 161
LEU P 269
GLY P 130
ALA P 132
LEU P 136
None
0.98A20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
1y7x MAJOR VAULT PROTEIN
(Homo
sapiens)
5 / 12LEU A  66
LEU A  36
ILE A  59
GLY A  94
ALA A  95
None
1.03A11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
3su8 PLEXIN-B1
(Homo
sapiens)
5 / 12LEU X1640
LEU X1610
PHE X1577
GLY X2083
ALA X2084
None
1.08A22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
3tw8 DENN
DOMAIN-CONTAINING
PROTEIN 1B
(Homo
sapiens)
5 / 12LEU A 186
ILE A 210
GLY A 212
ALA A 214
LEU A 217
None
1.11A21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
3wsy SORTILIN-RELATED
RECEPTOR
(Homo
sapiens)
5 / 12HIS A 415
LEU A 453
GLY A 502
ALA A 526
SER A 525
None
1.11A22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
4h27 L-SERINE
DEHYDRATASE/L-THREON
INE DEAMINASE
(Homo
sapiens)
5 / 12ILE A 282
GLY A  24
ALA A  23
SER A  20
LEU A  19
None
1.12A20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
4ky9 BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens)
5 / 12HIS A 161
LEU A 269
GLY A 130
ALA A 132
LEU A 136
None
1.00A20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens)
5 / 12LEU A 614
TYR A 609
LEU A 390
GLY A 354
ALA A 355
None
0.98A19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
4rs1 GRANULOCYTE-MACROPHA
GE
COLONY-STIMULATING
FACTOR
(Homo
sapiens)
5 / 12HIS A  15
LEU A  77
TYR A  84
LEU A  55
ILE A  19
None
1.09A10.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5ikr PROSTAGLANDIN G/H
SYNTHASE 2
(Homo
sapiens)
10 / 12HIS A  90
ARG A 120
LEU A 352
TYR A 355
LEU A 359
TRP A 387
GLY A 526
ALA A 527
SER A 530
LEU A 531
None
ID8  A 601 ( 4.4A)
ID8  A 601 (-4.1A)
ID8  A 601 (-3.8A)
None
COH  A 602 (-4.5A)
ID8  A 601 (-3.5A)
ID8  A 601 (-3.5A)
ID8  A 601 (-2.7A)
ID8  A 601 (-3.5A)
0.62A63.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5ikr PROSTAGLANDIN G/H
SYNTHASE 2
(Homo
sapiens)
8 / 12LEU A 352
TYR A 355
LEU A 359
TRP A 387
PHE A 518
GLY A 526
SER A 530
LEU A 531
ID8  A 601 (-4.1A)
ID8  A 601 (-3.8A)
None
COH  A 602 (-4.5A)
None
ID8  A 601 (-3.5A)
ID8  A 601 (-2.7A)
ID8  A 601 (-3.5A)
0.80A63.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5jo5 10E8 GLV
(Homo
sapiens)
5 / 12PHE L  62
ILE L  75
GLY L  77
ALA L  78
LEU L  15
None
1.08A17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5l6q H5AL
(Homo
sapiens)
5 / 12PHE A  60
ILE A  73
GLY A  75
ALA A  76
LEU A  13
None
1.11A12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5m32 PROTEASOME SUBUNIT
BETA TYPE-2
(Homo
sapiens)
5 / 12LEU J   4
TYR J 117
GLY J 135
ALA J 136
LEU J 140
None
1.02A16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
1zq9 PROBABLE
DIMETHYLADENOSINE
TRANSFERASE
(Homo
sapiens)
3 / 3VAL A 232
VAL A 247
SER A 244
None
0.73A17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
2j3s FILAMIN-A
(Homo
sapiens)
3 / 3VAL A2134
VAL A2090
SER A2088
None
0.63A19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
2ypd PROBABLE JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION PROT
EIN 2C
(Homo
sapiens)
3 / 3VAL A2477
VAL A2197
SER A2284
None
0.65A22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
3nby SNURPORTIN-1
(Homo
sapiens)
3 / 3VAL B 281
VAL B 244
SER B 246
None
0.68A20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
4jy4 PGT121 HEAVY CHAIN
(Homo
sapiens)
3 / 3VAL B  51
VAL B  67
SER B  81
None
0.71A16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
5fzo PROBABLE JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION PROT
EIN 2C
(Homo
sapiens)
3 / 3VAL A2477
VAL A2197
SER A2284
None
0.68A22.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
5ikr PROSTAGLANDIN G/H
SYNTHASE 2
(Homo
sapiens)
3 / 3VAL A 116
VAL A 349
SER A 353
None
ID8  A 601 (-3.9A)
ID8  A 601 ( 4.7A)
0.19A63.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
5vhs 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 3
(Homo
sapiens)
3 / 3VAL V 438
VAL V 458
SER V 460
None
0.52A20.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
1d7w MYELOPEROXIDASE
(Homo
sapiens)
6 / 7GLN A  91
HIS A  95
ARG C 239
GLU C 242
PHE C 366
PRO C 220
HEM  A 605 ( 3.4A)
CYN  A1844 (-4.1A)
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
None
None
1.34A38.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
1d7w MYELOPEROXIDASE
(Homo
sapiens)
6 / 7GLN A  91
HIS A  95
GLU A 102
ARG C 239
GLU C 242
PHE C 366
HEM  A 605 ( 3.4A)
CYN  A1844 (-4.1A)
None
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
None
0.69A38.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
1d7w MYELOPEROXIDASE
(Homo
sapiens)
6 / 7GLN A  91
HIS A  95
GLU A 102
ARG C 239
GLU C 242
PHE C 407
HEM  A 605 ( 3.4A)
CYN  A1844 (-4.1A)
None
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
HEM  A 605 (-4.5A)
1.38A38.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
1ijt FIBROBLAST GROWTH
FACTOR 4
(Homo
sapiens)
4 / 7GLU A 159
ARG A 123
GLU A 122
PRO A 120
None
1.37A12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
1uch UBIQUITIN C-TERMINAL
HYDROLASE UCH-L3
(Homo
sapiens)
4 / 7HIS A 169
GLU A  70
ARG A 186
PHE A  86
None
1.34A16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
2qnk 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Homo
sapiens)
4 / 7HIS A  91
GLU A 129
PHE A 170
PRO A 169
NI  A 287 (-3.3A)
None
None
None
1.35A19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
3d3l ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Homo
sapiens)
4 / 7HIS A 462
GLU A 643
ARG A 641
GLU A 637
None
1.28A20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
3dwb ENDOTHELIN-CONVERTIN
G ENZYME 1
(Homo
sapiens)
4 / 7GLN A 548
GLU A 575
PHE A 509
PRO A 507
5HD  A 816 ( 4.7A)
None
5HD  A 816 ( 3.9A)
None
1.37A22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
4nre ARACHIDONATE
15-LIPOXYGENASE B
(Homo
sapiens)
4 / 7GLN A 560
HIS A 373
GLU A 671
PRO A 614
None
C8E  A 702 ( 3.5A)
GOL  A 718 ( 4.8A)
None
1.20A23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
4wxx DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1
(Homo
sapiens)
4 / 7GLU A 877
GLU A1322
PHE A1262
PRO A1325
None
1.35A19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
5c08 1E6 TCR ALPHA CHAIN
1E6 TCR BETA CHAIN
(Homo
sapiens)
4 / 7GLN E  37
GLU D   5
ARG E  41
PRO D   8
None
1.32A17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
5h64 SERINE/THREONINE-PRO
TEIN KINASE MTOR
(Homo
sapiens)
4 / 7HIS A2355
GLU A2373
ARG A2339
PRO A2376
None
1.39A13.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
5mfa MYELOPEROXIDASE
(Homo
sapiens)
5 / 7GLN A 257
HIS A 261
ARG A 405
PHE A 532
PRO A 386
HEM  A 812 (-3.3A)
None
HEM  A 812 (-3.7A)
TRS  A 824 ( 4.8A)
TRS  A 824 ( 4.6A)
1.34A49.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
5mfa MYELOPEROXIDASE
(Homo
sapiens)
4 / 7GLN A 257
HIS A 261
ARG A 405
PHE A 573
HEM  A 812 (-3.3A)
None
HEM  A 812 (-3.7A)
HEM  A 812 ( 3.9A)
0.84A49.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
5mfa MYELOPEROXIDASE
(Homo
sapiens)
5 / 7GLN A 257
HIS A 261
GLU A 268
ARG A 405
PHE A 532
HEM  A 812 (-3.3A)
None
HEM  A 812 ( 4.9A)
HEM  A 812 (-3.7A)
TRS  A 824 ( 4.8A)
0.73A49.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
5mfa MYELOPEROXIDASE
(Homo
sapiens)
4 / 7HIS A 261
GLU A 408
PHE A 532
PRO A 386
None
HEM  A 812 (-4.2A)
TRS  A 824 ( 4.8A)
TRS  A 824 ( 4.6A)
1.32A49.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
5xgj PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT ALPHA
ISOFORM
(Homo
sapiens)
4 / 7GLN A 630
GLU A 259
PHE A 666
PRO A 757
None
1.35A8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
6azp MYELOPEROXIDASE
(Homo
sapiens)
5 / 7GLN A 257
HIS A 261
ARG A 405
PHE A 532
PRO A 386
None
1.39A11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
6azp MYELOPEROXIDASE
(Homo
sapiens)
5 / 7GLN A 257
HIS A 261
GLU A 268
ARG A 405
PHE A 532
None
0.86A11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
6azp MYELOPEROXIDASE
(Homo
sapiens)
5 / 7GLN A 257
HIS A 261
GLU A 268
ARG A 405
PHE A 573
None
1.19A11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)
6caj TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT BETA
(Homo
sapiens)
4 / 7ARG C 172
GLU C  32
PHE C 272
PRO C 270
None
1.28A8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
1ldj CULLIN HOMOLOG 1
(Homo
sapiens)
4 / 4LEU A 756
ALA A 714
ILE A 711
LYS A 759
None
1.49A9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
1snz ALDOSE 1-EPIMERASE
(Homo
sapiens)
4 / 4LEU A 106
ALA A  80
ILE A  76
LYS A 101
None
1.31A14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
2zmc DUAL SPECIFICITY
PROTEIN KINASE TTK
(Homo
sapiens)
4 / 4LEU A 648
ALA A 634
ILE A 638
LYS A 649
None
1.39A13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
3kvo HYDROXYSTEROID
DEHYDROGENASE-LIKE
PROTEIN 2
(Homo
sapiens)
4 / 4LEU A  69
ALA A  58
ILE A  54
LYS A  87
None
1.47A15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
3mdy BONE MORPHOGENETIC
PROTEIN RECEPTOR
TYPE-1B
(Homo
sapiens)
4 / 4LEU A 176
ALA A 263
ILE A 200
LYS A 174
None
1.49A15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
4o27 SERINE/THREONINE-PRO
TEIN KINASE 24
(Homo
sapiens)
4 / 4LEU B 247
ALA B 122
ILE B 121
LYS B 248
None
1.29A17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1
(Homo
sapiens;
synthetic
construct)
4 / 4LEU A2417
ALA A2404
ILE A2288
LYS A2416
None
1.17A3.12