POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		1u31 NAD(P)
TRANSHYDROGENASE,
MITOCHONDRIAL
(Homo
sapiens)		3 / 3ASN A 130
TYR A 179
SER A 135
NDP  A 300 (-4.3A)
None
None
0.89A19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens)		3 / 3ASN A 467
TYR A 361
SER A 340
None
0.85A21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		2wya HYDROXYMETHYLGLUTARY
L-COA SYNTHASE,
MITOCHONDRIAL
(Homo
sapiens)		3 / 3ASN A 465
TYR A  76
SER A 202
None
0.94A21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		2yf0 MYOTUBULARIN-RELATED
PROTEIN 6
(Homo
sapiens)		3 / 3ASN A 329
TYR A 192
SER A 331
None
0.85A22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		3al5 JMJC
DOMAIN-CONTAINING
PROTEIN C2ORF60
(Homo
sapiens)		3 / 3ASN A 166
TYR A 264
SER A 145
None
0.91A21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		3g04 HUMAN THYROID
STIMULATING
AUTOANTIBODY M22
HEAVY CHAIN
THYROTROPIN RECEPTOR
(Homo
sapiens)		3 / 3ASN B  58
TYR C  82
SER B 100
None
0.94A19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		3hhd FATTY ACID SYNTHASE
(Homo
sapiens)		3 / 3ASN A 189
TYR A 222
SER A 336
None
0.62A20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		3oes GTPASE RHEBL1
(Homo
sapiens)		3 / 3ASN A  41
TYR A  35
SER A  21
None
GNP  A 201 (-4.5A)
GNP  A 201 (-2.6A)
0.94A18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		3zyj LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 4C
(Homo
sapiens)		3 / 3ASN A 214
TYR A 166
SER A 189
None
0.94A22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens)		3 / 3ASN A  44
TYR A 122
SER A  37
None
0.69A19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		5fuc INTERLEUKIN-6
RECEPTOR SUBUNIT
ALPHA, INTERLEUKIN-6
RECEPTOR
VHH6
(Camelus
dromedarius;
Homo
sapiens)		3 / 3ASN C 226
TYR E  59
SER C 228
NAG  C1299 (-1.8A)
None
None
0.86A22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		5u6o POTASSIUM/SODIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 1
(Homo
sapiens)		3 / 3ASN A 107
TYR A 144
SER A 139
None
0.88A20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		6d4j PROTEIN PATCHED
HOMOLOG 1
(Homo
sapiens)		3 / 3ASN A 168
TYR A 797
SER A 356
None
0.66A11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		6f2u ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3
(Homo
sapiens)		3 / 3ASN A 189
TYR A 319
SER A 118
None
None
CJ2  A 402 ( 3.7A)
0.93A13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		1u31 NAD(P)
TRANSHYDROGENASE,
MITOCHONDRIAL
(Homo
sapiens)		3 / 3ASN A 130
TYR A 179
SER A 135
NDP  A 300 (-4.3A)
None
None
0.88A19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		2wya HYDROXYMETHYLGLUTARY
L-COA SYNTHASE,
MITOCHONDRIAL
(Homo
sapiens)		3 / 3ASN A 465
TYR A  76
SER A 202
None
0.95A21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		2yf0 MYOTUBULARIN-RELATED
PROTEIN 6
(Homo
sapiens)		3 / 3ASN A 329
TYR A 192
SER A 331
None
0.80A22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		3al5 JMJC
DOMAIN-CONTAINING
PROTEIN C2ORF60
(Homo
sapiens)		3 / 3ASN A 166
TYR A 264
SER A 145
None
0.90A21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		3hhd FATTY ACID SYNTHASE
(Homo
sapiens)		3 / 3ASN A 189
TYR A 222
SER A 336
None
0.56A20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		3zyj LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 4C
(Homo
sapiens)		3 / 3ASN A 214
TYR A 166
SER A 189
None
0.91A22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		4mel UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 11
(Homo
sapiens)		3 / 3ASN A  44
TYR A 122
SER A  37
None
0.70A19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		5fuc INTERLEUKIN-6
RECEPTOR SUBUNIT
ALPHA, INTERLEUKIN-6
RECEPTOR
VHH6
(Camelus
dromedarius;
Homo
sapiens)		3 / 3ASN C 226
TYR E  59
SER C 228
NAG  C1299 (-1.8A)
None
None
0.84A22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		5u6o POTASSIUM/SODIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 1
(Homo
sapiens)		3 / 3ASN A 107
TYR A 144
SER A 139
None
0.90A20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		6d4j PROTEIN PATCHED
HOMOLOG 1
(Homo
sapiens)		3 / 3ASN A 168
TYR A 797
SER A 356
None
0.70A11.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		1d7w MYELOPEROXIDASE
(Homo
sapiens)		5 / 5GLN A  91
HIS A  95
ARG C 239
GLU C 242
LEU C 246
HEM  A 605 ( 3.4A)
CYN  A1844 (-4.1A)
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
None
0.35A38.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		3qfs NADPH--CYTOCHROME
P450 REDUCTASE
(Homo
sapiens)		4 / 5HIS A 446
ARG A 246
GLU A 391
LEU A 450
None
1.50A23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		5clw 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME
(Homo
sapiens)		4 / 5GLN A 566
HIS A 545
ARG A 565
LEU A 569
None
1.47A20.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
ARG A 405
LEU A 412
HEM  A 812 (-3.3A)
None
HEM  A 812 (-3.7A)
None
0.37A49.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
GLU A 408
LEU A 412
HEM  A 812 (-3.3A)
None
HEM  A 812 (-4.2A)
None
0.91A49.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
ARG A 405
LEU A 412
None
0.45A11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
GLU A 408
LEU A 412
None
0.95A11.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		1d7w MYELOPEROXIDASE
(Homo
sapiens)		5 / 5GLN A  91
HIS A  95
ARG C 239
GLU C 242
LEU C 246
HEM  A 605 ( 3.4A)
CYN  A1844 (-4.1A)
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
None
0.34A38.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		3qfs NADPH--CYTOCHROME
P450 REDUCTASE
(Homo
sapiens)		4 / 5HIS A 446
ARG A 246
GLU A 391
LEU A 450
None
1.48A23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		5clw 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME
(Homo
sapiens)		4 / 5GLN A 566
HIS A 545
ARG A 565
LEU A 569
None
1.47A20.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
ARG A 405
LEU A 412
HEM  A 812 (-3.3A)
None
HEM  A 812 (-3.7A)
None
0.31A49.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
GLU A 408
LEU A 412
HEM  A 812 (-3.3A)
None
HEM  A 812 (-4.2A)
None
0.97A49.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
ARG A 405
LEU A 412
None
0.40A11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
GLU A 408
LEU A 412
None
0.99A11.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		1d7w MYELOPEROXIDASE
(Homo
sapiens)		5 / 5GLN A  91
HIS A  95
ARG C 239
GLU C 242
LEU C 246
HEM  A 605 ( 3.4A)
CYN  A1844 (-4.1A)
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
None
0.31A38.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		5clw 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME
(Homo
sapiens)		4 / 5GLN A 566
HIS A 545
ARG A 565
LEU A 569
None
1.45A20.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
ARG A 405
LEU A 412
HEM  A 812 (-3.3A)
None
HEM  A 812 (-3.7A)
None
0.24A49.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
GLU A 408
LEU A 412
HEM  A 812 (-3.3A)
None
HEM  A 812 (-4.2A)
None
0.95A49.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
ARG A 405
LEU A 412
None
0.37A11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
GLU A 408
LEU A 412
None
0.98A11.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		1d7w MYELOPEROXIDASE
(Homo
sapiens)		5 / 5GLN A  91
HIS A  95
ARG C 239
GLU C 242
LEU C 246
HEM  A 605 ( 3.4A)
CYN  A1844 (-4.1A)
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
None
0.31A38.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		5clw 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME
(Homo
sapiens)		4 / 5GLN A 566
HIS A 545
ARG A 565
LEU A 569
None
1.45A20.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
ARG A 405
LEU A 412
HEM  A 812 (-3.3A)
None
HEM  A 812 (-3.7A)
None
0.24A49.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
GLU A 408
LEU A 412
HEM  A 812 (-3.3A)
None
HEM  A 812 (-4.2A)
None
0.95A49.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
ARG A 405
LEU A 412
None
0.37A11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
GLU A 408
LEU A 412
None
0.98A11.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		1d7w MYELOPEROXIDASE
(Homo
sapiens)		5 / 5GLN A  91
HIS A  95
ARG C 239
GLU C 242
LEU C 246
HEM  A 605 ( 3.4A)
CYN  A1844 (-4.1A)
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
None
0.31A38.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		5clw 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME
(Homo
sapiens)		4 / 5GLN A 566
HIS A 545
ARG A 565
LEU A 569
None
1.45A20.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
ARG A 405
LEU A 412
HEM  A 812 (-3.3A)
None
HEM  A 812 (-3.7A)
None
0.25A49.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
GLU A 408
LEU A 412
HEM  A 812 (-3.3A)
None
HEM  A 812 (-4.2A)
None
0.94A49.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
ARG A 405
LEU A 412
None
0.37A11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
GLU A 408
LEU A 412
None
0.97A11.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		1d7w MYELOPEROXIDASE
(Homo
sapiens)		5 / 5GLN A  91
HIS A  95
ARG C 239
GLU C 242
LEU C 246
HEM  A 605 ( 3.4A)
CYN  A1844 (-4.1A)
HEM  A 605 (-4.3A)
HEM  A 605 (-2.1A)
None
0.31A38.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		5clw 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME
(Homo
sapiens)		4 / 5GLN A 566
HIS A 545
ARG A 565
LEU A 569
None
1.45A20.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
ARG A 405
LEU A 412
HEM  A 812 (-3.3A)
None
HEM  A 812 (-3.7A)
None
0.25A49.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		5mfa MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
GLU A 408
LEU A 412
HEM  A 812 (-3.3A)
None
HEM  A 812 (-4.2A)
None
0.94A49.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
ARG A 405
LEU A 412
None
0.37A11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		6azp MYELOPEROXIDASE
(Homo
sapiens)		4 / 5GLN A 257
HIS A 261
GLU A 408
LEU A 412
None
0.97A11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		1sqw SACCHAROMYCES
CEREVISIAE NIP7P
HOMOLOG
(Homo
sapiens)		3 / 3ASN A 124
SER A 126
SER A 149
None
0.49A18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		2hz0 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens)		3 / 3ASN A 297
SER A 349
SER A 348
None
0.63A20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		2v40 ADENYLOSUCCINATE
SYNTHETASE ISOZYME 2
(Homo
sapiens)		3 / 3ASN A 255
SER A 272
SER A 271
None
0.68A21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		4on3 SORTING NEXIN-10
(Homo
sapiens)		3 / 3ASN A  67
SER A 116
SER A 115
None
0.64A18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		4xey TYROSINE-PROTEIN
KINASE ABL1
(Homo
sapiens)		3 / 3ASN B 316
SER B 368
SER B 367
None
0.68A22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		5gs0 TOLL-LIKE RECEPTOR 3
(Homo
sapiens)		3 / 3ASN A 230
SER A 205
SER A 179
None
0.64A19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		5j6s ENDOPLASMIC
RETICULUM
AMINOPEPTIDASE 2
(Homo
sapiens)		3 / 3ASN A 714
SER A 716
SER A 719
NAG  A1012 (-1.9A)
None
None
0.78A19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		6ez8 HUNTINGTIN
(Homo
sapiens)		3 / 3ASN A1886
SER A 835
SER A 836
None
0.79A8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_C_MMZC503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		4xb0 SERINE/THREONINE-PRO
TEIN KINASE PLK2
(Homo
sapiens)		4 / 4TYR A 645
ASN A 671
SER A 667
SER A 666
None
1.27A18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_C_MMZC503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		5buo AMYLOID BETA A4
PROTEIN
(Homo
sapiens)		4 / 4TYR A 401
ASN A 475
SER A 471
SER A 469
None
1.40A20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_C_MMZC503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		5m76 LIGHT CHAIN DIMER
(Homo
sapiens)		4 / 4TYR A  32
ASN A  25
SER A  94
SER A  93
None
1.46A19.62