POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	1jy1	TYROSYL-DNA PHOSPHODIESTERASE (Homo sapiens)	3 / 3	LEU A 275 LEU A 270 SER A 198	None	0.56A	14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	1kwm	PROCARBOXYPEPTIDASE B (Homo sapiens)	3 / 3	LEU A 108 LEU A  49 SER A  36	None	0.51A	15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	1us7	HSP90 CO-CHAPERONE CDC37 (Homo sapiens)	3 / 3	LEU B 305 LEU B 301 SER B 300	None	0.68A	19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	1v5j	KIAA1355 PROTEIN (Homo sapiens)	3 / 3	LEU A  42 LEU A  80 SER A  92	None	0.67A	24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	1wgv	KIAA1068 PROTEIN (Homo sapiens)	3 / 3	LEU A  31 LEU A  97 SER A  83	None	0.65A	20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	1ya5	TELETHONIN (Homo sapiens)	3 / 3	LEU T  60 LEU T  30 SER T   4	None	0.57A	19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	1zli	CARBOXYPEPTIDASE B (Homo sapiens)	3 / 3	LEU A 108 LEU A  49 SER A  36	None	0.68A	16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	2f8v	TELETHONIN (Homo sapiens)	3 / 3	LEU T  60 LEU T  30 SER T   4	None	0.56A	19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	2iuw	ALKYLATED REPAIR PROTEIN ALKB HOMOLOG 3 (Homo sapiens)	3 / 3	LEU A  92 LEU A 245 SER A 206	None None AKG  A 700 ( 4.1A)	0.61A	18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	2ylf	PROTEIN SPIRE HOMOLOG 1 (Homo sapiens)	3 / 3	LEU A 156 LEU A 153 SER A 150	None	0.64A	22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	3bg9	PYRUVATE CARBOXYLASE, MITOCHONDRIAL (Homo sapiens)	3 / 3	LEU A1037 LEU A1033 SER A1032	None	0.65A	10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	3f8u	TAPASIN (Homo sapiens)	3 / 3	LEU B 115 LEU B 142 SER B 161	None None NAG  B1233 ( 4.6A)	0.44A	14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	3mud	DNA REPAIR PROTEIN XRCC4,TROPOMYOSIN ALPHA-1 CHAIN (Gallus gallus; Homo sapiens)	3 / 3	LEU A  36 LEU A  20 SER A   6	None	0.61A	24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	3nxp	PRETHROMBIN-1 (Homo sapiens)	3 / 3	LEU A 505 LEU A 453 SER A 445	None	0.64A	14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	3r7g	PROTEIN SPIRE HOMOLOG 1 (Homo sapiens)	3 / 3	LEU A 156 LEU A 153 SER A 150	None	0.64A	22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	3zkj	ANKYRIN REPEAT AND SOCS BOX PROTEIN 9 (Homo sapiens)	3 / 3	LEU A 217 LEU A 214 SER A 211	None None CL  A1297 (-3.5A)	0.68A	17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLM_A_MILA128_1 (TRANSTHYRETIN)	4cak	INTEGRIN ALPHA-IIB (Homo sapiens)	3 / 3	LEU A 567 LEU A 460 SER A 728	None	0.59A	8.65