POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	1h4l	CELL DIVISION PROTEIN KINASE 5 (Homo sapiens)	9 / 12	ILE A 10 VAL A 18 LYS A 33 VAL A 64 PHE A 80 ASP A 86 ASN A 131 LEU A 133 ALA A 143	None	0.89A	45.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	1rjb	FL CYTOKINE RECEPTOR (Homo sapiens)	8 / 12	VAL A 624 LYS A 644 VAL A 675 PHE A 691 ASP A 698 ASN A 816 LEU A 818 ASP A 829	None	0.91A	26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	1t46	HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG (Homo sapiens)	6 / 12	VAL A 603 LYS A 623 VAL A 654 ASP A 677 ASN A 797 LEU A 799	STI A 3 ( 4.6A) STI A 3 (-3.7A) STI A 3 (-4.3A) None None STI A 3 (-4.4A)	0.61A	26.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	1zrz	PROTEIN KINASE C, IOTA (Homo sapiens)	8 / 12	VAL A 259 LYS A 274 VAL A 307 VAL A 326 ASP A 330 ASN A 374 LEU A 376 ASP A 387	BI1 A1000 (-4.2A) BI1 A1000 (-3.5A) BI1 A1000 (-4.4A) BI1 A1000 (-3.9A) BI1 A1000 (-4.3A) None BI1 A1000 (-4.8A) BI1 A1000 (-4.5A)	0.94A	27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 12	VAL X 25 LYS X 39 VAL X 67 ASN X 135 LEU X 137 ALA X 147 ASP X 148	STU X 902 ( 4.8A) STU X 902 (-3.1A) None STU X 902 ( 4.9A) STU X 902 (-4.4A) STU X 902 ( 4.1A) STU X 902 (-3.6A)	0.62A	24.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	2eu9	DUAL SPECIFICITY PROTEIN KINASE CLK3 (Homo sapiens)	8 / 12	VAL A 170 LYS A 186 VAL A 220 PHE A 236 ASN A 288 LEU A 290 ALA A 319 ASP A 320	None	0.64A	31.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	7 / 12	VAL A 256 LYS A 271 VAL A 299 ASN A 368 LEU A 370 ALA A 380 ASP A 381	GIN A 600 ( 4.7A) GIN A 600 (-3.6A) GIN A 600 (-4.6A) None GIN A 600 (-4.7A) GIN A 600 (-3.1A) GIN A 600 (-4.9A)	0.69A	26.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	2jgz	CELL DIVISION PROTEIN KINASE 2 (Homo sapiens)	8 / 12	ILE A 10 VAL A 18 VAL A 64 PHE A 80 ASN A 132 LEU A 134 ALA A 144 ASP A 145	None	0.84A	49.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	2jgz	CELL DIVISION PROTEIN KINASE 2 (Homo sapiens)	8 / 12	VAL A 18 VAL A 64 PHE A 80 ASP A 86 ASN A 132 LEU A 134 ALA A 144 ASP A 145	None	0.66A	49.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	2v55	RHO-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	8 / 12	ILE A 82 VAL A 90 LYS A 105 VAL A 137 ASP A 160 ASN A 203 LEU A 205 ALA A 215	None None ANP A1480 (-3.4A) ANP A1480 (-4.7A) ANP A1480 (-4.0A) MG A1481 (-3.5A) ANP A1480 ( 4.7A) ANP A1480 ( 4.1A)	0.89A	25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	2v55	RHO-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	7 / 12	LYS A 105 VAL A 137 ASP A 160 ASN A 203 LEU A 205 ALA A 215 ASP A 216	ANP A1480 (-3.4A) ANP A1480 (-4.7A) ANP A1480 (-4.0A) MG A1481 (-3.5A) ANP A1480 ( 4.7A) ANP A1480 ( 4.1A) ANP A1480 (-3.5A)	0.84A	25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	2vd5	DMPK PROTEIN (Homo sapiens)	8 / 12	VAL A 85 LYS A 100 ASP A 155 THR A 158 ASN A 200 LEU A 202 ALA A 212 ASP A 213	BI8 A1417 ( 4.7A) BI8 A1417 (-4.2A) None None BI8 A1417 (-3.6A) BI8 A1417 (-4.8A) BI8 A1417 ( 4.1A) BI8 A1417 (-3.8A)	0.82A	25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	2vuw	SERINE/THREONINE-PRO TEIN KINASE HASPIN (Homo sapiens)	8 / 12	ILE A 490 VAL A 498 LYS A 511 PHE A 605 ASP A 611 ASN A 654 LEU A 656 ASP A 687	None 5ID A1800 ( 4.5A) IOD A1799 (-3.2A) 5ID A1800 (-4.1A) 5ID A1800 (-3.6A) None 5ID A1800 (-4.5A) IOD A1799 (-4.0A)	0.72A	24.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	2w9f	CELL DIVISION PROTEIN KINASE 4 (Homo sapiens)	8 / 12	ILE B 12 VAL B 20 VAL B 72 PHE B 93 VAL B 96 THR B 102 LEU B 147 ALA B 157	None	0.92A	69.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	2w9f	CELL DIVISION PROTEIN KINASE 4 (Homo sapiens)	9 / 12	VAL B 20 VAL B 72 PHE B 93 VAL B 96 ASP B 99 THR B 102 ASN B 145 LEU B 147 ALA B 157	None	0.80A	69.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	8 / 12	VAL A 76 LYS A 94 VAL A 125 ASP A 148 THR A 151 ASN A 192 LEU A 194 ASP A 205	None STU A 1 (-2.8A) None STU A 1 (-3.8A) None STU A 1 (-4.3A) STU A 1 (-4.6A) STU A 1 ( 3.8A)	0.77A	29.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3bhh	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE II BETA CHAIN (Homo sapiens)	7 / 12	VAL A 28 PHE A 90 VAL A 93 ASN A 141 LEU A 143 ALA A 156 ASP A 157	5CP A 600 ( 4.4A) 5CP A 600 ( 4.3A) 5CP A 600 ( 3.7A) None 5CP A 600 (-4.4A) 5CP A 600 ( 3.9A) 5CP A 600 (-3.5A)	0.74A	31.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3bhh	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE II BETA CHAIN (Homo sapiens)	7 / 12	VAL A 28 VAL A 74 PHE A 90 ASN A 141 LEU A 143 ALA A 156 ASP A 157	5CP A 600 ( 4.4A) 5CP A 600 ( 4.7A) 5CP A 600 ( 4.3A) None 5CP A 600 (-4.4A) 5CP A 600 ( 3.9A) 5CP A 600 (-3.5A)	0.62A	31.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3c0i	PERIPHERAL PLASMA MEMBRANE PROTEIN CASK (Homo sapiens)	6 / 12	ILE A 18 VAL A 26 LYS A 41 VAL A 75 PHE A 91 LEU A 148	3AM A 338 (-4.5A) 3AM A 338 ( 4.1A) 3AM A 338 (-2.9A) None 3AM A 338 (-3.6A) 3AM A 338 (-4.7A)	0.56A	28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	7 / 12	ILE A 201 VAL A 209 LYS A 222 VAL A 249 ASN A 319 LEU A 321 ASP A 332	None	0.81A	25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3f2a	PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE PIM-1 (Homo sapiens)	6 / 12	VAL A 52 LYS A 67 ASP A 128 ASN A 172 LEU A 174 ASP A 186	985 A 1 (-4.5A) 985 A 1 ( 2.8A) 985 A 1 (-4.7A) 985 A 1 (-4.6A) 985 A 1 (-4.8A) 985 A 1 ( 4.0A)	0.61A	27.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3mdy	BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B (Homo sapiens)	7 / 12	ILE A 210 VAL A 218 LYS A 231 ASN A 337 LEU A 339 ALA A 349 ASP A 350	LDN A 1 (-4.1A) LDN A 1 ( 4.8A) None LDN A 1 (-4.3A) LDN A 1 (-4.5A) LDN A 1 ( 3.8A) LDN A 1 (-3.9A)	0.84A	28.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3mi9	CELL DIVISION PROTEIN KINASE 9 (Homo sapiens)	10 / 12	ILE A 25 VAL A 33 LYS A 48 VAL A 79 PHE A 103 ASP A 109 ASN A 154 LEU A 156 ALA A 166 ASP A 167	None	0.81A	37.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3mtl	CELL DIVISION PROTEIN KINASE 16 (Homo sapiens)	8 / 12	VAL A 179 LYS A 194 VAL A 224 PHE A 240 ASP A 246 ASN A 291 LEU A 293 ALA A 303	FEF A 668 (-4.9A) None FEF A 668 (-4.7A) FEF A 668 ( 4.3A) FEF A 668 ( 4.3A) FEF A 668 (-3.9A) FEF A 668 (-4.2A) FEF A 668 ( 4.0A)	0.76A	40.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3mvj	CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	7 / 12	VAL A 57 LYS A 72 VAL A 104 VAL A 123 ASN A 171 LEU A 173 ASP A 184	XFE A 351 ( 4.5A) None None XFE A 351 (-4.2A) None XFE A 351 (-4.6A) None	0.68A	25.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	6 / 12	VAL A 200 VAL A 247 ASP A 270 ASN A 316 LEU A 318 ASP A 329	AMP A 577 (-4.3A) None AMP A 577 (-3.6A) AMP A 577 (-4.2A) AMP A 577 (-4.8A) AMP A 577 (-4.0A)	0.66A	21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3qfv	CDC42BPB PROTEIN (Homo sapiens)	9 / 12	ILE A 82 VAL A 90 LYS A 105 ASP A 160 THR A 163 ASN A 205 LEU A 207 ALA A 217 ASP A 218	None NM7 A 416 (-3.7A) EDO A 417 (-3.5A) None None None NM7 A 416 ( 4.2A) NM7 A 416 ( 4.5A) EDO A 417 (-3.7A)	0.78A	26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3she	MAP KINASE-ACTIVATED PROTEIN KINASE 3 (Homo sapiens)	6 / 12	VAL A 58 LYS A 73 VAL A 98 ASN A 171 LEU A 173 ASP A 187	I85 A 350 (-4.9A) I85 A 350 (-2.8A) None I85 A 350 (-4.4A) None I85 A 350 (-3.3A)	0.66A	25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	8 / 12	VAL A 369 LYS A 384 VAL A 436 ASP A 440 ASN A 484 LEU A 486 ALA A 496 ASP A 497	07U A 1 (-4.8A) 07U A 1 (-3.0A) 07U A 1 (-3.8A) 07U A 1 (-3.9A) None 07U A 1 (-4.3A) 07U A 1 ( 4.0A) 07U A 1 (-3.6A)	0.66A	26.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	3zdu	CYCLIN-DEPENDENT KINASE-LIKE 3 (Homo sapiens)	7 / 12	VAL A 18 LYS A 33 VAL A 63 PHE A 79 ASN A 130 LEU A 132 ASP A 143	38R A 350 ( 4.8A) 38R A 350 (-2.9A) 38R A 350 ( 4.9A) 38R A 350 (-4.1A) 38R A 350 (-4.2A) 38R A 350 (-4.3A) NA A 353 ( 2.5A)	0.60A	35.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4agu	CYCLIN-DEPENDENT KINASE-LIKE 1 (Homo sapiens)	8 / 12	ILE A 10 VAL A 18 LYS A 33 VAL A 64 PHE A 80 ASN A 131 LEU A 133 ASP A 144	D15 A 500 (-4.2A) D15 A 500 (-4.6A) D15 A 500 ( 4.1A) None D15 A 500 ( 4.3A) D15 A 500 (-3.0A) D15 A 500 (-4.5A) D15 A 500 (-3.7A)	0.79A	36.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4bbm	CYCLIN-DEPENDENT KINASE-LIKE 2 (Homo sapiens)	7 / 12	VAL A 18 VAL A 64 PHE A 80 VAL A 83 ASN A 131 LEU A 133 ASP A 144	None TC0 A 500 (-4.7A) TC0 A 500 (-3.4A) TC0 A 500 (-4.4A) None TC0 A 500 (-4.3A) TC0 A 500 (-4.8A)	0.56A	35.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4bgq	CYCLIN-DEPENDENT KINASE-LIKE 5 (Homo sapiens)	6 / 12	VAL A 27 LYS A 42 VAL A 73 PHE A 89 VAL A 92 LEU A 142	38R A1000 ( 4.8A) 38R A1000 (-3.4A) None 38R A1000 ( 3.8A) 38R A1000 (-4.1A) 38R A1000 ( 4.5A)	0.44A	35.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4crs	SERINE/THREONINE-PRO TEIN KINASE N2 (Homo sapiens)	8 / 12	VAL A 671 LYS A 686 VAL A 721 ASP A 744 ASN A 787 LEU A 789 ALA A 799 ASP A 800	AGS A1985 (-4.6A) AGS A1985 (-3.0A) None AGS A1985 (-4.0A) MG A1986 ( 3.2A) AGS A1985 (-4.8A) AGS A1985 ( 4.5A) AGS A1985 ( 3.3A)	0.63A	26.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4ez5	CYCLIN-DEPENDENT KINASE 6 (Homo sapiens)	12 / 12	ILE A 19 VAL A 27 LYS A 43 VAL A 77 PHE A 98 VAL A 101 ASP A 104 THR A 107 ASN A 150 LEU A 152 ALA A 162 ASP A 163	0RS A 900 (-4.1A) None 0RS A 900 (-3.3A) 0RS A 900 (-4.4A) 0RS A 900 (-4.5A) 0RS A 900 (-4.5A) 0RS A 900 (-4.2A) 0RS A 900 (-4.2A) None 0RS A 900 (-4.3A) 0RS A 900 (-3.6A) 0RS A 900 (-3.6A)	0.95A	98.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4ez5	CYCLIN-DEPENDENT KINASE 6 (Homo sapiens)	9 / 12	VAL A 27 LYS A 43 VAL A 77 PHE A 98 VAL A 101 ASP A 104 THR A 106 LEU A 152 ALA A 162	None 0RS A 900 (-3.3A) 0RS A 900 (-4.4A) 0RS A 900 (-4.5A) 0RS A 900 (-4.5A) 0RS A 900 (-4.2A) None 0RS A 900 (-4.3A) 0RS A 900 (-3.6A)	1.39A	98.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4fr4	SERINE/THREONINE-PRO TEIN KINASE 32A (Homo sapiens)	7 / 12	ILE A 29 VAL A 37 VAL A 84 ASP A 107 ASN A 151 LEU A 153 ASP A 164	STU A 401 (-4.1A) STU A 401 ( 4.9A) None STU A 401 (-3.3A) STU A 401 ( 4.8A) STU A 401 (-4.7A) STU A 401 ( 3.9A)	0.76A	24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	VAL A 836 LYS A 855 VAL A 884 ASN A 954 LEU A 956 ALA A 966 ASP A 967	19S A1201 (-4.4A) 19S A1201 (-3.5A) None None 19S A1201 (-4.5A) 19S A1201 ( 4.1A) 19S A1201 ( 4.1A)	0.60A	25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4idt	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 (Homo sapiens)	6 / 12	VAL A 414 LYS A 429 VAL A 453 ASN A 520 LEU A 522 ASP A 534	T28 A 701 (-4.7A) T28 A 701 ( 3.8A) None T28 A 701 ( 4.9A) T28 A 701 (-3.9A) T28 A 701 ( 3.4A)	0.64A	24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4l52	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7, TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1 CHIMERA (Homo sapiens)	6 / 12	VAL A 50 LYS A 63 VAL A 90 ASN A 161 LEU A 163 ASP A 175	1UL A 501 ( 4.9A) None None None 1UL A 501 (-4.3A) 1UL A 501 (-4.2A)	0.62A	28.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4oav	PROTEIN (RNASE L) (Homo sapiens)	7 / 12	ILE B 371 LYS B 392 VAL B 418 ASN B 490 LEU B 492 ALA B 502 ASP B 503	ACP B 801 (-4.2A) ACP B 801 (-2.8A) None MG B 802 ( 2.5A) ACP B 801 (-4.5A) None MG B 803 (-1.8A)	0.81A	18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4otd	SERINE/THREONINE-PRO TEIN KINASE N1 (Homo sapiens)	8 / 12	VAL A 635 LYS A 650 VAL A 685 ASP A 708 ASN A 751 LEU A 753 ALA A 763 ASP A 764	None	0.85A	27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4rew	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (Homo sapiens)	7 / 12	VAL A 32 LYS A 47 VAL A 98 ASN A 146 LEU A 148 ALA A 158 ASP A 159	STU A 601 ( 4.8A) STU A 601 ( 3.7A) STU A 601 (-4.1A) STU A 601 (-4.2A) STU A 601 (-4.2A) STU A 601 ( 3.8A) STU A 601 (-3.7A)	0.65A	21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4rt7	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	7 / 12	LYS A 644 VAL A 675 PHE A 691 ASP A 698 ASN A 816 LEU A 818 ASP A 829	P30 A1001 (-3.4A) None P30 A1001 (-3.7A) None None P30 A1001 (-4.6A) None	0.89A	23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4rt7	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	7 / 12	VAL A 624 LYS A 644 VAL A 675 PHE A 691 ASP A 698 ASN A 816 LEU A 818	None P30 A1001 (-3.4A) None P30 A1001 (-3.7A) None None P30 A1001 (-4.6A)	0.71A	23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4wb7	DNAJ HOMOLOG SUBFAMILY B MEMBER 1,CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	7 / 12	VAL A 112 LYS A 127 VAL A 159 VAL A 178 ASN A 226 LEU A 228 ASP A 239	ATP A 501 (-4.0A) ATP A 501 (-2.6A) None ATP A 501 (-4.2A) ZN A 502 ( 2.5A) ATP A 501 (-4.5A) ZN A 503 (-1.9A)	0.69A	25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4xuf	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	7 / 12	VAL A 624 LYS A 644 VAL A 675 PHE A 691 ASP A 698 ASN A 816 LEU A 818	P30 A1001 ( 4.8A) P30 A1001 ( 4.0A) None P30 A1001 ( 4.3A) None None P30 A1001 (-4.3A)	0.78A	28.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 12	VAL A 18 VAL A 64 PHE A 80 ASP A 86 ASN A 133 LEU A 135 ALA A 145	None	0.85A	46.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4yff	SERINE/THREONINE-PRO TEIN KINASE TNNI3K (Homo sapiens)	7 / 12	ILE A 469 VAL A 477 LYS A 490 ASN A 593 LEU A 595 ALA A 605 ASP A 606	4CV A 801 (-4.3A) None 4CV A 801 (-3.9A) None 4CV A 801 (-4.4A) 4CV A 801 ( 3.9A) 4CV A 801 (-3.5A)	0.61A	27.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	4ylj	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 1A (Homo sapiens)	8 / 12	ILE A 165 VAL A 173 LYS A 188 VAL A 222 PHE A 238 ASN A 292 LEU A 294 ASP A 307	4E1 A 505 ( 4.6A) 4E1 A 505 (-4.5A) 4E1 A 505 (-2.7A) None 4E1 A 505 (-4.2A) None None 4E1 A 505 (-3.6A)	0.69A	29.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5ci7	SERINE/THREONINE-PRO TEIN KINASE ULK1 (Homo sapiens)	6 / 12	VAL A 30 VAL A 76 ASP A 99 ASN A 143 LEU A 145 ALA A 164	51W A 401 ( 4.3A) None 51W A 401 (-3.8A) GOL A 404 ( 4.6A) 51W A 401 (-4.5A) None	0.49A	29.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5es1	MAP/MICROTUBULE AFFINITY-REGULATING KINASE 4 (Homo sapiens)	7 / 12	VAL A 70 LYS A 85 VAL A 116 ASN A 183 LEU A 185 ALA A 195 ASP A 196	5RC A4000 (-4.6A) 5RC A4000 (-2.8A) None 5RC A4000 (-4.1A) None 5RC A4000 ( 3.9A) 5RC A4000 (-3.6A)	0.76A	27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5f1z	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	6 / 12	VAL A 911 LYS A 930 VAL A 981 ASN A1028 LEU A1030 ASP A1041	5U3 A1200 ( 4.4A) None 5U3 A1200 (-3.5A) 5U3 A1200 (-4.7A) 5U3 A1200 (-4.4A) 5U3 A1200 ( 4.9A)	0.60A	25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	6 / 12	VAL A 607 LYS A 627 VAL A 658 ASP A 681 ASN A 823 LEU A 825	748 A1001 ( 4.7A) 748 A1001 (-4.0A) 748 A1001 ( 4.8A) None None 748 A1001 (-4.3A)	0.60A	26.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5idn	CYCLIN-DEPENDENT KINASE 8 (Homo sapiens)	7 / 12	LYS A 52 PHE A 97 ASP A 103 ASN A 156 LEU A 158 ALA A 172 ASP A 173	6A7 A 401 ( 2.9A) 6A7 A 401 (-3.8A) 6A7 A 401 ( 4.9A) FMT A 403 ( 4.7A) 6A7 A 401 (-4.8A) 6A7 A 401 ( 4.1A) FMT A 403 ( 3.3A)	1.00A	33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5idn	CYCLIN-DEPENDENT KINASE 8 (Homo sapiens)	7 / 12	VAL A 35 LYS A 52 PHE A 97 ASP A 103 LEU A 158 ALA A 172 ASP A 173	6A7 A 401 ( 4.5A) 6A7 A 401 ( 2.9A) 6A7 A 401 (-3.8A) 6A7 A 401 ( 4.9A) 6A7 A 401 (-4.8A) 6A7 A 401 ( 4.1A) FMT A 403 ( 3.3A)	0.85A	33.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5iso	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 (Homo sapiens)	7 / 12	VAL A 30 LYS A 45 VAL A 96 ASN A 144 LEU A 146 ALA A 156 ASP A 157	STU A 601 (-4.8A) STU A 601 ( 4.4A) STU A 601 (-4.0A) STU A 601 (-4.3A) STU A 601 (-4.5A) STU A 601 (-3.5A) STU A 601 (-3.5A)	0.66A	22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	8 / 12	ILE A 22 VAL A 30 LYS A 45 VAL A 74 ASN A 141 LEU A 143 ALA A 153 ASP A 154	6G2 A 901 (-3.8A) 6G2 A 901 ( 4.9A) 6G2 A 901 ( 3.9A) None None 6G2 A 901 (-4.7A) 6G2 A 901 ( 4.2A) 6G2 A 901 (-3.4A)	0.69A	27.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5jzn	SERINE/THREONINE-PRO TEIN KINASE DCLK1 (Homo sapiens)	7 / 12	VAL A 404 VAL A 449 VAL A 468 ASP A 472 ASN A 516 LEU A 518 ASP A 533	GUI A 701 (-4.4A) None GUI A 701 (-4.0A) None GUI A 701 (-4.4A) GUI A 701 (-4.4A) GUI A 701 ( 4.8A)	0.74A	32.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5lxd	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 2 (Homo sapiens)	7 / 12	ILE A 155 VAL A 163 LYS A 178 PHE A 228 ASN A 280 LEU A 282 ASP A 295	7A7 A 501 ( 4.3A) 7A7 A 501 (-4.4A) 7A7 A 501 (-3.5A) 7A7 A 501 (-3.7A) 7A7 A 501 ( 4.8A) 7A7 A 501 (-4.9A) 7A7 A 501 (-3.2A)	0.56A	26.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5mov	CASEIN KINASE II SUBUNIT ALPHA (Homo sapiens)	6 / 12	VAL A 53 LYS A 68 PHE A 113 VAL A 116 ASN A 161 ASP A 175	None HC4 A 401 (-2.7A) HC4 A 401 (-3.4A) None None HC4 A 401 (-4.0A)	0.61A	29.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5tur	SERINE/THREONINE-PRO TEIN KINASE PIM-1 (Homo sapiens)	6 / 12	VAL A 52 LYS A 67 ASP A 128 ASN A 172 LEU A 174 ASP A 186	7LK A 401 (-4.9A) None 7LK A 401 ( 3.9A) None 7LK A 401 (-4.8A) None	0.58A	23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5u7q	RHO-ASSOCIATED PROTEIN KINASE 2 (Homo sapiens)	8 / 12	VAL A 106 LYS A 121 VAL A 153 ASP A 176 ASN A 219 LEU A 221 ALA A 231 ASP A 232	None	0.73A	26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5vil	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (Homo sapiens)	7 / 12	VAL A 694 LYS A 709 VAL A 738 VAL A 757 ASN A 808 LEU A 810 ASP A 822	9E1 A1001 ( 4.0A) 9E1 A1001 (-2.8A) 9E1 A1001 (-4.1A) 9E1 A1001 (-3.9A) 9E1 A1001 ( 4.0A) 9E1 A1001 (-4.5A) 9E1 A1001 (-3.6A)	0.50A	17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 12	ILE A 215 VAL A 223 LYS A 238 PHE A 288 ASN A 340 LEU A 342 ASP A 355	None HRM A 601 ( 4.9A) HRM A 601 (-3.3A) HRM A 601 (-3.6A) None None HRM A 601 (-4.7A)	0.75A	13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 12	VAL A 223 LYS A 238 PHE A 288 ASP A 294 ASN A 340 LEU A 342 ASP A 355	HRM A 601 ( 4.9A) HRM A 601 (-3.3A) HRM A 601 (-3.6A) None None None HRM A 601 (-4.7A)	0.59A	13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6b3e	CYCLIN-DEPENDENT KINASE 12 (Homo sapiens)	10 / 12	ILE A 733 VAL A 741 LYS A 756 VAL A 787 PHE A 813 ASP A 819 ASN A 864 LEU A 866 ALA A 876 ASP A 877	CJM A1102 (-3.4A) None None None CJM A1102 ( 4.4A) CJM A1102 (-4.1A) MG A1101 ( 4.4A) CJM A1102 (-4.4A) CJM A1102 (-3.6A) MG A1101 (-2.5A)	0.76A	16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	ILE A 171 VAL A 179 LYS A 194 VAL A 249 PHE A 267 VAL A 270 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 ( 4.8A) NH4 A 506 ( 4.4A) None BI9 A 501 ( 4.2A) BI9 A 501 (-4.0A) BI9 A 501 (-4.7A)	0.87A	13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	VAL A 179 LYS A 194 VAL A 249 PHE A 267 VAL A 270 ASN A 317 LEU A 319 ALA A 329	BI9 A 501 ( 4.8A) NH4 A 506 ( 4.4A) None BI9 A 501 ( 4.2A) BI9 A 501 (-4.0A) BI9 A 501 (-4.5A) BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A)	0.93A	13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 249 PHE A 267 VAL A 270 ASN A 317 LEU A 319 ALA A 329 ASP A 330	None BI9 A 501 ( 4.2A) BI9 A 501 (-4.0A) BI9 A 501 (-4.5A) BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A) None	0.84A	13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6c9d	SERINE/THREONINE-PRO TEIN KINASE MARK1,SERINE/THREONI NE-PROTEIN KINASE MARK1 (Homo sapiens)	8 / 12	ILE A 66 VAL A 74 LYS A 89 VAL A 120 ASN A 187 LEU A 189 ALA A 199 ASP A 200	None	0.82A	12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6ccf	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 1 (Homo sapiens)	8 / 12	VAL A 142 LYS A 157 VAL A 212 PHE A 230 ASN A 280 LEU A 282 ALA A 292 ASP A 293	H1N A 501 (-4.4A) H1N A 501 (-2.8A) H1N A 501 (-4.9A) H1N A 501 (-3.7A) H1N A 501 (-4.5A) H1N A 501 (-4.8A) H1N A 501 ( 3.9A) H1N A 501 (-3.5A)	0.65A	15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	10 / 12	ILE A 171 VAL A 179 LYS A 194 VAL A 249 PHE A 267 VAL A 270 ASN A 317 LEU A 319 ALA A 329 ASP A 330	F6J A 501 (-4.3A) F6J A 501 (-4.6A) F6J A 501 (-2.9A) None F6J A 501 (-3.7A) F6J A 501 (-4.0A) F6J A 501 ( 4.7A) F6J A 501 (-4.5A) F6J A 501 ( 4.0A) F6J A 501 (-3.8A)	0.76A	11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6fyl	DUAL SPECIFICITY PROTEIN KINASE CLK2 (Homo sapiens)	7 / 12	VAL A 177 LYS A 193 VAL A 227 PHE A 243 ASN A 295 LEU A 297 ASP A 327	3NG A 501 ( 4.4A) 3NG A 501 (-3.0A) None 3NG A 501 (-3.5A) None None 3NG A 501 (-4.5A)	0.86A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6fyo	DUAL SPECIFICITY PROTEIN KINASE CLK1 (Homo sapiens)	7 / 12	VAL A 175 LYS A 191 VAL A 225 PHE A 241 ASN A 293 LEU A 295 ASP A 325	None EAQ A 501 (-3.2A) None EAQ A 501 (-3.5A) None EAQ A 501 (-4.9A) EAQ A 501 (-4.6A)	0.66A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6fyv	DUAL SPECIFICITY PROTEIN KINASE CLK4 (Homo sapiens)	7 / 12	VAL A 175 LYS A 191 VAL A 225 PHE A 241 ASN A 293 LEU A 295 ASP A 325	3NG A 501 ( 4.3A) 3NG A 501 (-2.7A) None 3NG A 501 (-3.5A) None None 3NG A 501 (-4.3A)	0.68A	undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	1h4l	CELL DIVISION PROTEIN KINASE 5 (Homo sapiens)	7 / 12	VAL A 18 ALA A 31 VAL A 64 PHE A 80 ASP A 86 LEU A 133 ALA A 143	None	0.77A	45.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	1rjb	FL CYTOKINE RECEPTOR (Homo sapiens)	7 / 12	GLY A 617 VAL A 624 ALA A 642 VAL A 675 PHE A 691 ASP A 698 LEU A 818	None	0.60A	25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	1snx	TYROSINE-PROTEIN KINASE ITK/TSK (Homo sapiens)	6 / 12	GLY A 370 VAL A 377 ALA A 389 VAL A 419 PHE A 435 LEU A 489	None	0.50A	27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	1t46	HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG (Homo sapiens)	6 / 12	GLY A 596 VAL A 603 ALA A 621 VAL A 654 ASP A 677 LEU A 799	None STI A 3 ( 4.6A) STI A 3 (-3.5A) STI A 3 (-4.3A) None STI A 3 (-4.4A)	0.53A	26.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	6 / 12	GLY X 18 VAL X 25 ALA X 37 VAL X 67 LEU X 137 ALA X 147	STU X 902 ( 3.7A) STU X 902 ( 4.8A) STU X 902 (-3.1A) None STU X 902 (-4.4A) STU X 902 ( 4.1A)	0.46A	26.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	6 / 12	VAL X 25 ALA X 37 VAL X 67 LEU X 137 ALA X 147 ASP X 148	STU X 902 ( 4.8A) STU X 902 (-3.1A) None STU X 902 (-4.4A) STU X 902 ( 4.1A) STU X 902 (-3.6A)	0.63A	26.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2eu9	DUAL SPECIFICITY PROTEIN KINASE CLK3 (Homo sapiens)	7 / 12	GLY A 163 VAL A 170 ALA A 184 VAL A 220 PHE A 236 LEU A 290 ALA A 319	None	0.83A	30.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2h8h	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	6 / 12	GLY A 274 VAL A 281 ALA A 293 VAL A 323 LEU A 393 ALA A 403	H8H A 534 ( 3.8A) H8H A 534 (-4.4A) H8H A 534 (-3.2A) None H8H A 534 (-4.5A) H8H A 534 ( 4.0A)	0.72A	20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	6 / 12	GLY A 249 VAL A 256 ALA A 269 VAL A 299 LEU A 370 ALA A 380	None GIN A 600 ( 4.7A) GIN A 600 (-3.1A) GIN A 600 (-4.6A) GIN A 600 (-4.7A) GIN A 600 (-3.1A)	0.47A	25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2jgz	CELL DIVISION PROTEIN KINASE 2 (Homo sapiens)	7 / 12	ALA A 31 VAL A 64 PHE A 80 ASP A 86 LEU A 134 ALA A 144 ASP A 145	None	0.69A	48.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2jgz	CELL DIVISION PROTEIN KINASE 2 (Homo sapiens)	8 / 12	GLY A 11 VAL A 18 ALA A 31 VAL A 64 PHE A 80 ASP A 86 LEU A 134 ALA A 144	None	0.66A	48.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2ogv	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR PRECURSOR (Homo sapiens)	6 / 12	GLY A 589 VAL A 596 ALA A 614 VAL A 647 ASP A 670 LEU A 785	None	0.56A	23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2v55	RHO-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	7 / 12	GLY A 83 VAL A 90 ALA A 103 VAL A 137 ASP A 160 LEU A 205 ALA A 215	ANP A1480 ( 4.3A) None ANP A1480 ( 3.9A) ANP A1480 (-4.7A) ANP A1480 (-4.0A) ANP A1480 ( 4.7A) ANP A1480 ( 4.1A)	0.65A	26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2vuw	SERINE/THREONINE-PRO TEIN KINASE HASPIN (Homo sapiens)	7 / 12	ILE A 490 GLY A 491 VAL A 498 ALA A 509 PHE A 605 ASP A 611 LEU A 656	None 5ID A1800 (-3.5A) 5ID A1800 ( 4.5A) 5ID A1800 (-3.4A) 5ID A1800 (-4.1A) 5ID A1800 (-3.6A) 5ID A1800 (-4.5A)	0.85A	24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	6 / 12	GLY A 53 VAL A 60 ALA A 73 LEU A 171 ALA A 184 ASP A 185	DKI A1338 (-3.3A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) DKI A1338 (-4.9A) DKI A1338 (-3.1A) DKI A1338 (-3.8A)	0.68A	27.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2w9f	CELL DIVISION PROTEIN KINASE 4 (Homo sapiens)	9 / 12	GLY B 13 VAL B 20 ALA B 33 VAL B 72 PHE B 93 ASP B 99 THR B 102 LEU B 147 ALA B 157	None	0.63A	69.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2w9f	CELL DIVISION PROTEIN KINASE 4 (Homo sapiens)	9 / 12	ILE B 12 GLY B 13 VAL B 20 ALA B 33 VAL B 72 PHE B 93 THR B 102 LEU B 147 ALA B 157	None	0.77A	69.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	7 / 12	GLY A 69 VAL A 76 ALA A 92 VAL A 125 ASP A 148 THR A 151 LEU A 194	STU A 1 (-3.3A) None STU A 1 (-3.3A) None STU A 1 (-3.8A) None STU A 1 (-4.6A)	0.63A	29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	7 / 12	VAL A 76 ALA A 92 VAL A 125 ASP A 148 THR A 151 LEU A 194 ASP A 205	None STU A 1 (-3.3A) None STU A 1 (-3.8A) None STU A 1 (-4.6A) STU A 1 ( 3.8A)	0.74A	29.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3bhh	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE II BETA CHAIN (Homo sapiens)	7 / 12	VAL A 28 ALA A 41 VAL A 74 PHE A 90 LEU A 143 ALA A 156 ASP A 157	5CP A 600 ( 4.4A) 5CP A 600 (-3.6A) 5CP A 600 ( 4.7A) 5CP A 600 ( 4.3A) 5CP A 600 (-4.4A) 5CP A 600 ( 3.9A) 5CP A 600 (-3.5A)	0.63A	30.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3c0i	PERIPHERAL PLASMA MEMBRANE PROTEIN CASK (Homo sapiens)	7 / 12	ILE A 18 GLY A 19 VAL A 26 ALA A 39 VAL A 75 PHE A 91 LEU A 148	3AM A 338 (-4.5A) None 3AM A 338 ( 4.1A) 3AM A 338 (-3.3A) None 3AM A 338 (-3.6A) 3AM A 338 (-4.7A)	0.68A	26.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	6 / 12	ILE A 201 GLY A 202 VAL A 209 ALA A 220 VAL A 249 LEU A 321	None	0.72A	25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3dak	SERINE/THREONINE-PRO TEIN KINASE OSR1 (Homo sapiens)	7 / 12	ILE A 23 GLY A 24 VAL A 31 ALA A 44 VAL A 76 LEU A 153 ALA A 163	ANP A 1 (-4.2A) ANP A 1 (-3.3A) ANP A 1 (-4.5A) ANP A 1 ( 3.9A) None None MG A 296 ( 3.9A)	0.73A	26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3f2a	PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE PIM-1 (Homo sapiens)	6 / 12	GLY A 45 VAL A 52 ALA A 65 ASP A 128 LEU A 174 ASP A 186	985 A 1 ( 3.9A) 985 A 1 (-4.5A) 985 A 1 (-3.5A) 985 A 1 (-4.7A) 985 A 1 (-4.8A) 985 A 1 ( 4.0A)	0.66A	26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3iec	SERINE/THREONINE-PRO TEIN KINASE MARK2 (Homo sapiens)	6 / 12	GLY A 60 VAL A 67 ALA A 80 VAL A 113 LEU A 182 ALA A 192	None	0.70A	27.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3mdy	BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B (Homo sapiens)	6 / 12	GLY A 211 VAL A 218 ALA A 229 LEU A 339 ALA A 349 ASP A 350	LDN A 1 ( 4.7A) LDN A 1 ( 4.8A) LDN A 1 (-3.6A) LDN A 1 (-4.5A) LDN A 1 ( 3.8A) LDN A 1 (-3.9A)	0.70A	27.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3mi9	CELL DIVISION PROTEIN KINASE 9 (Homo sapiens)	7 / 12	ALA A 46 VAL A 79 PHE A 103 ASP A 109 LEU A 156 ALA A 166 ASP A 167	None	0.82A	36.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3mi9	CELL DIVISION PROTEIN KINASE 9 (Homo sapiens)	8 / 12	ILE A 25 VAL A 33 ALA A 46 VAL A 79 PHE A 103 ASP A 109 LEU A 156 ALA A 166	None	0.78A	36.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3mtl	CELL DIVISION PROTEIN KINASE 16 (Homo sapiens)	8 / 12	GLY A 172 VAL A 179 ALA A 192 VAL A 224 PHE A 240 ASP A 246 LEU A 293 ALA A 303	FEF A 668 ( 4.2A) FEF A 668 (-4.9A) FEF A 668 (-3.3A) FEF A 668 (-4.7A) FEF A 668 ( 4.3A) FEF A 668 ( 4.3A) FEF A 668 (-4.2A) FEF A 668 ( 4.0A)	0.56A	39.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	6 / 12	GLY A 193 VAL A 200 ALA A 213 VAL A 247 ASP A 270 LEU A 318	AMP A 577 ( 3.7A) AMP A 577 (-4.3A) AMP A 577 (-3.4A) None AMP A 577 (-3.6A) AMP A 577 (-4.8A)	0.58A	21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3qfv	CDC42BPB PROTEIN (Homo sapiens)	8 / 12	GLY A 83 VAL A 90 ALA A 103 ASP A 160 THR A 163 LEU A 207 ALA A 217 ASP A 218	NM7 A 416 (-3.0A) NM7 A 416 (-3.7A) NM7 A 416 ( 3.7A) None None NM7 A 416 ( 4.2A) NM7 A 416 ( 4.5A) EDO A 417 (-3.7A)	0.66A	25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	6 / 12	GLY A 362 VAL A 369 ALA A 382 ASP A 440 LEU A 486 ALA A 496	07U A 1 ( 4.2A) 07U A 1 (-4.8A) 07U A 1 (-3.3A) 07U A 1 (-3.9A) 07U A 1 (-4.3A) 07U A 1 ( 4.0A)	0.46A	27.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	3zdu	CYCLIN-DEPENDENT KINASE-LIKE 3 (Homo sapiens)	7 / 12	GLY A 11 TYR A 15 VAL A 18 ALA A 31 VAL A 63 PHE A 79 LEU A 132	38R A 350 ( 3.9A) None 38R A 350 ( 4.8A) 38R A 350 (-3.4A) 38R A 350 ( 4.9A) 38R A 350 (-4.1A) 38R A 350 (-4.3A)	0.79A	33.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4agu	CYCLIN-DEPENDENT KINASE-LIKE 1 (Homo sapiens)	7 / 12	ILE A 10 GLY A 11 VAL A 18 ALA A 31 VAL A 64 PHE A 80 LEU A 133	D15 A 500 (-4.2A) D15 A 500 (-3.8A) D15 A 500 (-4.6A) D15 A 500 (-3.4A) None D15 A 500 ( 4.3A) D15 A 500 (-4.5A)	0.64A	35.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4at3	BDNF/NT-3 GROWTH FACTORS RECEPTOR (Homo sapiens)	7 / 12	GLY A 561 VAL A 568 ALA A 586 VAL A 617 PHE A 633 ASP A 640 LEU A 699	LTI A1839 ( 4.3A) None LTI A1839 (-3.3A) None LTI A1839 (-3.5A) None LTI A1839 (-4.2A)	1.20A	27.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4bbm	CYCLIN-DEPENDENT KINASE-LIKE 2 (Homo sapiens)	6 / 12	VAL A 18 ALA A 31 VAL A 64 PHE A 80 LEU A 133 ASP A 144	None TC0 A 500 (-3.5A) TC0 A 500 (-4.7A) TC0 A 500 (-3.4A) TC0 A 500 (-4.3A) TC0 A 500 (-4.8A)	0.58A	33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4bgq	CYCLIN-DEPENDENT KINASE-LIKE 5 (Homo sapiens)	7 / 12	GLY A 20 TYR A 24 VAL A 27 ALA A 40 VAL A 73 PHE A 89 LEU A 142	None 38R A1000 (-3.6A) 38R A1000 ( 4.8A) 38R A1000 (-3.4A) None 38R A1000 ( 3.8A) 38R A1000 ( 4.5A)	0.85A	35.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4crs	SERINE/THREONINE-PRO TEIN KINASE N2 (Homo sapiens)	6 / 12	VAL A 671 ALA A 684 VAL A 721 ASP A 744 LEU A 789 ALA A 799	AGS A1985 (-4.6A) AGS A1985 (-3.5A) None AGS A1985 (-4.0A) AGS A1985 (-4.8A) AGS A1985 ( 4.5A)	0.45A	26.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4e93	TYROSINE-PROTEIN KINASE FES/FPS (Homo sapiens)	6 / 12	ALA A 588 VAL A 620 ASP A 643 THR A 646 LEU A 690 ASP A 701	GUI A 901 (-3.4A) None GUI A 901 ( 4.8A) GUI A 901 ( 3.8A) GUI A 901 (-4.3A) GUI A 901 ( 4.1A)	0.65A	22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4e93	TYROSINE-PROTEIN KINASE FES/FPS (Homo sapiens)	8 / 12	ILE A 567 GLY A 568 VAL A 575 ALA A 588 VAL A 620 ASP A 643 THR A 646 LEU A 690	GUI A 901 (-4.0A) GUI A 901 ( 4.3A) GUI A 901 (-4.5A) GUI A 901 (-3.4A) None GUI A 901 ( 4.8A) GUI A 901 ( 3.8A) GUI A 901 (-4.3A)	1.03A	22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4eut	SERINE/THREONINE-PRO TEIN KINASE TBK1 (Homo sapiens)	6 / 12	GLY A 16 VAL A 23 ALA A 36 VAL A 68 THR A 96 ASP A 157	BX7 A 401 ( 3.7A) BX7 A 401 (-4.4A) BX7 A 401 (-3.4A) None BX7 A 401 ( 4.7A) BX7 A 401 ( 3.7A)	0.74A	26.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4ez5	CYCLIN-DEPENDENT KINASE 6 (Homo sapiens)	9 / 12	GLY A 20 VAL A 27 VAL A 77 PHE A 98 ASP A 104 THR A 106 LEU A 152 ALA A 162 ASP A 163	None None 0RS A 900 (-4.4A) 0RS A 900 (-4.5A) 0RS A 900 (-4.2A) None 0RS A 900 (-4.3A) 0RS A 900 (-3.6A) 0RS A 900 (-3.6A)	1.32A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4ez5	CYCLIN-DEPENDENT KINASE 6 (Homo sapiens)	11 / 12	ILE A 19 GLY A 20 VAL A 27 ALA A 41 VAL A 77 PHE A 98 ASP A 104 THR A 107 LEU A 152 ALA A 162 ASP A 163	0RS A 900 (-4.1A) None None 0RS A 900 ( 3.7A) 0RS A 900 (-4.4A) 0RS A 900 (-4.5A) 0RS A 900 (-4.2A) 0RS A 900 (-4.2A) 0RS A 900 (-4.3A) 0RS A 900 (-3.6A) 0RS A 900 (-3.6A)	0.55A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4f0i	HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR (Homo sapiens)	7 / 12	GLY A 516 VAL A 523 ALA A 541 VAL A 572 PHE A 588 ASP A 595 LEU A 656	None	0.83A	27.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4fr4	SERINE/THREONINE-PRO TEIN KINASE 32A (Homo sapiens)	7 / 12	ILE A 29 GLY A 30 VAL A 37 ALA A 50 VAL A 84 ASP A 107 LEU A 153	STU A 401 (-4.1A) STU A 401 (-3.3A) STU A 401 ( 4.9A) STU A 401 (-3.2A) None STU A 401 (-3.3A) STU A 401 (-4.7A)	0.74A	24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	GLY A 829 VAL A 836 ALA A 853 VAL A 884 LEU A 956 ALA A 966	19S A1201 (-3.7A) 19S A1201 (-4.4A) 19S A1201 (-3.3A) None 19S A1201 (-4.5A) 19S A1201 ( 4.1A)	0.56A	26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4otd	SERINE/THREONINE-PRO TEIN KINASE N1 (Homo sapiens)	7 / 12	GLY A 628 VAL A 635 ALA A 648 VAL A 685 ASP A 708 LEU A 753 ALA A 763	None	0.64A	27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4otd	SERINE/THREONINE-PRO TEIN KINASE N1 (Homo sapiens)	7 / 12	VAL A 635 ALA A 648 VAL A 685 ASP A 708 LEU A 753 ALA A 763 ASP A 764	None	0.89A	27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4q9z	HUMAN PROTEIN KINASE C THETA (Homo sapiens)	6 / 12	GLY A 387 VAL A 394 ALA A 407 ASP A 465 LEU A 511 ALA A 521	PZW A 801 ( 3.8A) PZW A 801 (-4.6A) PZW A 801 (-3.5A) None PZW A 801 (-4.8A) PZW A 801 ( 4.6A)	0.72A	28.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4qtb	MITOGEN-ACTIVATED PROTEIN KINASE 3 (Homo sapiens)	7 / 12	ILE A 48 GLY A 49 TYR A 53 VAL A 56 ALA A 69 ASP A 128 LEU A 173	38Z A 418 ( 4.4A) None 38Z A 418 (-3.5A) None 38Z A 418 (-3.4A) EDO A 413 (-2.9A) 38Z A 418 (-4.4A)	0.75A	34.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4rew	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (Homo sapiens)	6 / 12	GLY A 25 VAL A 32 ALA A 45 LEU A 148 ALA A 158 ASP A 159	STU A 601 (-3.5A) STU A 601 ( 4.8A) STU A 601 (-3.2A) STU A 601 (-4.2A) STU A 601 ( 3.8A) STU A 601 (-3.7A)	0.72A	20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4rt7	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	7 / 12	GLY A 617 VAL A 624 ALA A 642 VAL A 675 PHE A 691 ASP A 698 LEU A 818	None None P30 A1001 (-3.4A) None P30 A1001 (-3.7A) None P30 A1001 (-4.6A)	0.51A	23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4xuf	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	7 / 12	GLY A 617 VAL A 624 ALA A 642 VAL A 675 PHE A 691 ASP A 698 LEU A 818	None P30 A1001 ( 4.8A) P30 A1001 (-3.5A) None P30 A1001 ( 4.3A) None P30 A1001 (-4.3A)	0.54A	28.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 12	GLY A 13 ALA A 31 VAL A 64 ASP A 86 LEU A 135 ALA A 145 ASP A 146	None	1.34A	45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	7 / 12	VAL A 18 ALA A 31 VAL A 64 PHE A 80 ASP A 86 LEU A 135 ALA A 145	None	0.68A	45.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4yff	SERINE/THREONINE-PRO TEIN KINASE TNNI3K (Homo sapiens)	6 / 12	GLY A 470 VAL A 477 ALA A 488 LEU A 595 ALA A 605 ASP A 606	4CV A 801 ( 3.9A) None 4CV A 801 (-3.5A) 4CV A 801 (-4.4A) 4CV A 801 ( 3.9A) 4CV A 801 (-3.5A)	0.51A	26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4yff	SERINE/THREONINE-PRO TEIN KINASE TNNI3K (Homo sapiens)	6 / 12	ILE A 469 GLY A 470 VAL A 477 ALA A 488 LEU A 595 ALA A 605	4CV A 801 (-4.3A) 4CV A 801 ( 3.9A) None 4CV A 801 (-3.5A) 4CV A 801 (-4.4A) 4CV A 801 ( 3.9A)	0.69A	26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4yhj	G PROTEIN-COUPLED RECEPTOR KINASE 4 (Homo sapiens)	6 / 12	GLY A 194 VAL A 201 ALA A 214 VAL A 248 ASP A 271 LEU A 319	AN2 A 601 (-3.4A) AN2 A 601 (-4.0A) AN2 A 601 (-3.6A) None None None	0.71A	21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	4ylj	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 1A (Homo sapiens)	7 / 12	ILE A 165 GLY A 166 VAL A 173 ALA A 186 VAL A 222 PHE A 238 LEU A 294	4E1 A 505 ( 4.6A) 4E1 A 505 (-3.5A) 4E1 A 505 (-4.5A) 4E1 A 505 (-3.5A) None 4E1 A 505 (-4.2A) None	0.74A	29.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5ci7	SERINE/THREONINE-PRO TEIN KINASE ULK1 (Homo sapiens)	7 / 12	GLY A 23 VAL A 30 ALA A 44 VAL A 76 ASP A 99 ALA A 164 ASP A 165	51W A 401 (-3.3A) 51W A 401 ( 4.3A) 51W A 401 (-3.4A) None 51W A 401 (-3.8A) None GOL A 404 (-3.2A)	0.82A	29.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5ci7	SERINE/THREONINE-PRO TEIN KINASE ULK1 (Homo sapiens)	7 / 12	GLY A 23 VAL A 30 ALA A 44 VAL A 76 ASP A 99 LEU A 145 ALA A 164	51W A 401 (-3.3A) 51W A 401 ( 4.3A) 51W A 401 (-3.4A) None 51W A 401 (-3.8A) 51W A 401 (-4.5A) None	0.61A	29.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5es1	MAP/MICROTUBULE AFFINITY-REGULATING KINASE 4 (Homo sapiens)	6 / 12	GLY A 63 VAL A 70 ALA A 83 VAL A 116 LEU A 185 ALA A 195	5RC A4000 ( 4.3A) 5RC A4000 (-4.6A) 5RC A4000 (-3.6A) None None 5RC A4000 ( 3.9A)	0.65A	27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	6 / 12	GLY A 600 VAL A 607 ALA A 625 VAL A 658 ASP A 681 LEU A 825	None 748 A1001 ( 4.7A) 748 A1001 (-3.7A) 748 A1001 ( 4.8A) None 748 A1001 (-4.3A)	0.55A	26.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5idn	CYCLIN-DEPENDENT KINASE 8 (Homo sapiens)	6 / 12	GLY A 28 VAL A 35 ALA A 50 ASP A 103 LEU A 158 ALA A 172	6A7 A 401 (-3.6A) 6A7 A 401 ( 4.5A) 6A7 A 401 (-3.3A) 6A7 A 401 ( 4.9A) 6A7 A 401 (-4.8A) 6A7 A 401 ( 4.1A)	0.63A	32.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5idn	CYCLIN-DEPENDENT KINASE 8 (Homo sapiens)	6 / 12	GLY A 28 VAL A 35 ALA A 50 PHE A 97 LEU A 158 ALA A 172	6A7 A 401 (-3.6A) 6A7 A 401 ( 4.5A) 6A7 A 401 (-3.3A) 6A7 A 401 (-3.8A) 6A7 A 401 (-4.8A) 6A7 A 401 ( 4.1A)	0.68A	32.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5iso	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 (Homo sapiens)	6 / 12	GLY A 23 VAL A 30 ALA A 43 LEU A 146 ALA A 156 ASP A 157	STU A 601 (-3.4A) STU A 601 (-4.8A) STU A 601 (-3.3A) STU A 601 (-4.5A) STU A 601 (-3.5A) STU A 601 (-3.5A)	0.60A	22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	7 / 12	GLY A 23 VAL A 30 ALA A 43 VAL A 74 LEU A 143 ALA A 153 ASP A 154	None 6G2 A 901 ( 4.9A) 6G2 A 901 (-3.2A) None 6G2 A 901 (-4.7A) 6G2 A 901 ( 4.2A) 6G2 A 901 (-3.4A)	0.64A	26.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5jzn	SERINE/THREONINE-PRO TEIN KINASE DCLK1 (Homo sapiens)	6 / 12	GLY A 397 VAL A 404 ALA A 417 VAL A 449 ASP A 472 LEU A 518	GUI A 701 ( 3.8A) GUI A 701 (-4.4A) GUI A 701 ( 3.9A) None None GUI A 701 (-4.4A)	0.63A	31.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5loh	SERINE/THREONINE-PRO TEIN KINASE GREATWALL,SERINE/THR EONINE-PROTEIN KINASE GREATWALL (Homo sapiens)	6 / 12	ILE A 41 VAL A 49 ALA A 60 VAL A 94 ASP A 117 LEU A 163	STU A 901 (-4.3A) None STU A 901 (-3.3A) None STU A 901 (-4.2A) STU A 901 (-4.5A)	0.59A	27.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5lxd	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 2 (Homo sapiens)	6 / 12	ILE A 155 GLY A 156 VAL A 163 ALA A 176 PHE A 228 LEU A 282	7A7 A 501 ( 4.3A) 7A7 A 501 (-3.2A) 7A7 A 501 (-4.4A) 7A7 A 501 (-3.5A) 7A7 A 501 (-3.7A) 7A7 A 501 (-4.9A)	0.48A	26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	6 / 12	GLY A 99 VAL A 106 ALA A 119 VAL A 157 PHE A 177 LEU A 232	W4A A 716 ( 4.0A) W4A A 716 ( 4.7A) W4A A 716 ( 3.9A) DMS A 717 (-4.3A) DMS A 717 ( 3.9A) None	0.74A	26.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5u7q	RHO-ASSOCIATED PROTEIN KINASE 2 (Homo sapiens)	7 / 12	GLY A 99 VAL A 106 ALA A 119 VAL A 153 ASP A 176 LEU A 221 ALA A 231	None	0.55A	26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5xv7	SERINE-ARGININE (SR) PROTEIN KINASE 1 (Homo sapiens)	7 / 12	GLY A 87 VAL A 94 ALA A 107 VAL A 145 PHE A 165 LEU A 220 ALA A 496	EMH A 705 ( 3.9A) EMH A 705 ( 4.4A) EMH A 705 (-3.6A) EMH A 705 ( 4.9A) EMH A 705 (-3.6A) None EMH A 705 ( 4.0A)	0.89A	14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 12	GLY A 216 VAL A 223 ALA A 236 PHE A 288 ASP A 294 LEU A 342	None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 (-3.6A) None None	0.66A	13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	6b3e	CYCLIN-DEPENDENT KINASE 12 (Homo sapiens)	9 / 12	GLY A 734 VAL A 741 ALA A 754 VAL A 787 PHE A 813 ASP A 819 LEU A 866 ALA A 876 ASP A 877	CJM A1102 (-3.4A) None CJM A1102 (-3.1A) None CJM A1102 ( 4.4A) CJM A1102 (-4.1A) CJM A1102 (-4.4A) CJM A1102 (-3.6A) MG A1101 (-2.5A)	0.89A	16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	6b3e	CYCLIN-DEPENDENT KINASE 12 (Homo sapiens)	7 / 12	ILE A 733 GLY A 734 VAL A 741 ALA A 754 PHE A 813 ASP A 819 LEU A 866	CJM A1102 (-3.4A) CJM A1102 (-3.4A) None CJM A1102 (-3.1A) CJM A1102 ( 4.4A) CJM A1102 (-4.1A) CJM A1102 (-4.4A)	0.74A	16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	GLY A 172 VAL A 179 ALA A 192 VAL A 249 PHE A 267 LEU A 319 ALA A 329	BI9 A 501 (-3.6A) BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) None BI9 A 501 ( 4.2A) BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A)	0.84A	13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	6c9d	SERINE/THREONINE-PRO TEIN KINASE MARK1,SERINE/THREONI NE-PROTEIN KINASE MARK1 (Homo sapiens)	7 / 12	ILE A 66 GLY A 67 VAL A 74 ALA A 87 VAL A 120 LEU A 189 ALA A 199	None	0.91A	12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	6ccf	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 1 (Homo sapiens)	7 / 12	GLY A 135 TYR A 139 VAL A 142 ALA A 155 VAL A 212 LEU A 282 ALA A 292	H1N A 501 ( 3.8A) None H1N A 501 (-4.4A) H1N A 501 (-3.4A) H1N A 501 (-4.9A) H1N A 501 (-4.8A) H1N A 501 ( 3.9A)	0.70A	15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	6ccf	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 1 (Homo sapiens)	7 / 12	GLY A 135 VAL A 142 ALA A 155 VAL A 212 PHE A 230 LEU A 282 ALA A 292	H1N A 501 ( 3.8A) H1N A 501 (-4.4A) H1N A 501 (-3.4A) H1N A 501 (-4.9A) H1N A 501 (-3.7A) H1N A 501 (-4.8A) H1N A 501 ( 3.9A)	0.63A	15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	GLY A 172 VAL A 179 ALA A 192 VAL A 249 PHE A 267 LEU A 319 ALA A 329 ASP A 330	F6J A 501 ( 3.9A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) None F6J A 501 (-3.7A) F6J A 501 (-4.5A) F6J A 501 ( 4.0A) F6J A 501 (-3.8A)	0.81A	11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	6fyo	DUAL SPECIFICITY PROTEIN KINASE CLK1 (Homo sapiens)	6 / 12	GLY A 168 VAL A 175 ALA A 189 VAL A 225 PHE A 241 LEU A 295	None None EAQ A 501 (-3.6A) None EAQ A 501 (-3.5A) EAQ A 501 (-4.9A)	0.64A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_2 (CYCLIN-DEPENDENT KINASE 6)	3f81	DUAL SPECIFICITY PROTEIN PHOSPHATASE 3 (Homo sapiens)	4 / 4	LYS A 50 HIS A 123 VAL A 122 ASN A 31	None	1.48A	19.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L2I_A_LQQA900_2 (CYCLIN-DEPENDENT KINASE 6)	4ez5	CYCLIN-DEPENDENT KINASE 6 (Homo sapiens)	4 / 4	LYS A 43 HIS A 100 VAL A 101 ASN A 150	0RS A 900 (-3.3A) 0RS A 900 (-4.1A) 0RS A 900 (-4.5A) None	0.79A	100.00