POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	1axn	ANNEXIN III (Homo sapiens)	4 / 8	GLN A 125 ALA A 132 GLN A 131 SER A 130	None	1.18A	20.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	1kpb	HUMAN PROTEIN KINASE C INTERACTING PROTEIN 1 (ZINC PROTEIN) (Homo sapiens)	5 / 8	GLN A  47 ASN A  99 GLN A 106 HIS A 112 HIS A 114	None	0.28A	55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	1kpb	HUMAN PROTEIN KINASE C INTERACTING PROTEIN 1 (ZINC PROTEIN) (Homo sapiens)	5 / 8	GLN A  47 ASN A  99 GLN A 106 SER A 107 HIS A 114	None	0.63A	55.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	3q5e	ATLASTIN-1 (Homo sapiens)	4 / 8	GLN A 337 ALA A 350 GLN A 349 SER A 346	None	1.05A	14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	4c0d	CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 (Homo sapiens)	4 / 8	ASN A2272 ALA A2271 GLN A2273 HIS A2114	None	1.03A	11.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	4ini	HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL (Homo sapiens)	6 / 8	GLN A  84 ASN A 136 ALA A 142 GLN A 143 SER A 144 HIS A 151	1PE  A 202 ( 4.2A) AMP  A 201 (-3.8A) 1PE  A 202 ( 4.0A) None AMP  A 201 ( 2.6A) AMP  A 201 (-4.1A)	0.25A	91.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	4njz	HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL (Homo sapiens)	6 / 8	GLN A  84 ASN A 136 ALA A 142 GLN A 143 HIS A 149 HIS A 151	None None None None None SO4  A 201 (-4.8A)	0.25A	85.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	4njz	HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL (Homo sapiens)	6 / 8	GLN A  84 ASN A 136 ALA A 142 GLN A 143 SER A 144 HIS A 151	None None None None SO4  A 201 (-2.8A) SO4  A 201 (-4.8A)	0.51A	85.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	4nre	ARACHIDONATE 15-LIPOXYGENASE B (Homo sapiens)	4 / 8	ALA A 558 SER A 611 HIS A 373 HIS A 368	GOL  A 718 (-3.2A) None C8E  A 702 ( 3.5A) None	1.14A	13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	4pri	TK3 TCR BETA CHAIN (Homo sapiens)	4 / 8	GLN E   6 ALA E  78 GLN E  79 HIS E  86	None	1.14A	19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	4u7m	LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS PROTEIN 1 (Homo sapiens)	4 / 8	ALA A 519 SER A 517 HIS A 547 HIS A 549	None	1.07A	18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	5fu7	CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 (Homo sapiens)	4 / 8	ASN A2272 ALA A2271 GLN A2273 HIS A2114	None	1.05A	15.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	5km5	HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL (Homo sapiens)	6 / 8	GLN A  84 ASN A 136 ALA A 142 GLN A 143 SER A 144 HIS A 151	None CL  A 201 (-4.3A) None None CL  A 201 (-3.5A) CL  A 201 (-4.5A)	0.53A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	5mue	ALPHA-TOCOPHEROL TRANSFER PROTEIN (Homo sapiens)	4 / 8	TRP A 163 ALA A 168 GLN A 170 SER A 166	None	1.05A	21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	5w4x	UDP-GLUCOSE 6-DEHYDROGENASE (Homo sapiens)	4 / 8	GLN A 278 ALA A 228 GLN A 229 SER A 232	None	1.08A	16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	5zcs	TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 (Homo sapiens)	4 / 8	GLN C  63 GLN C  41 HIS C  40 HIS C  64	None	1.05A	15.44