POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	2iwz	3-OXOACYL-[ACYL-CARR IER-PROTEIN] SYNTHASE (Homo sapiens)	4 / 6	THR A 399 LEU A 400 THR A 442 LEU A 407	None None NH4  A1461 (-4.0A) None	1.18A	20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	3avs	LYSINE-SPECIFIC DEMETHYLASE 6A (Homo sapiens)	4 / 6	THR A1245 LEU A1244 MET A1291 LEU A1119	None None EDO  A1512 ( 3.2A) None	0.86A	20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	3c6g	CYTOCHROME P450 2R1 (Homo sapiens)	4 / 6	MET A 487 THR A 488 LEU A 489 LEU A 369	VD3  A 701 ( 4.5A) VD3  A 701 ( 4.6A) None None	1.17A	21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	3hd6	AMMONIUM TRANSPORTER RH TYPE C (Homo sapiens)	4 / 6	THR A 263 LEU A 262 THR A 318 LEU A 257	None	1.11A	20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	3naf	CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1,CALCIUM-ACTI VATED POTASSIUM CHANNEL SUBUNIT ALPHA-1,CALCIUM-ACTI VATED POTASSIUM CHANNEL SUBUNIT ALPHA-1 (Homo sapiens)	4 / 6	THR A 935 LEU A 936 THR A 946 LEU A 580	None	1.13A	16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	3p8c	NCK-ASSOCIATED PROTEIN 1 (Homo sapiens)	4 / 6	THR B 783 LEU B 787 THR B 717 LEU B 842	None	1.23A	13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	4doh	INTERLEUKIN-20 (Homo sapiens)	4 / 6	THR A 118 LEU A 117 THR A  37 LEU A 112	None	1.20A	20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	4e74	PLEXIN-A4 (Homo sapiens)	4 / 6	LEU A1584 MET A1563 THR A1571 LEU A1581	None None UNX  A1704 ( 4.4A) None	1.06A	14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	4qds	NEUROPILIN-2 (Homo sapiens)	4 / 6	THR A 337 LEU A 336 MET A 440 THR A 340	None	1.04A	19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	4zg7	ECTONUCLEOTIDE PYROPHOSPHATASE/PHOS PHODIESTERASE FAMILY MEMBER 2 (Homo sapiens)	4 / 6	THR A 851 LEU A 852 THR A 527 LEU A 856	None	1.21A	16.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	5ek0	CHIMERA OF BACTERIAL ION TRANSPORT PROTEIN AND HUMAN SODIUM CHANNEL PROTEIN TYPE 9 SUBUNIT ALPHA (Homo sapiens; Arcobacter butzleri)	4 / 6	MET A1677 THR A1678 LEU A1679 MET A1712	PX4  A1806 ( 4.3A) PX4  A1806 ( 4.8A) None PX4  A1806 ( 4.6A)	0.66A	82.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	5fxv	HISTONE DEMETHYLASE UTY (Homo sapiens)	4 / 6	THR A1192 LEU A1191 MET A1238 LEU A1066	None	1.10A	21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	5nug	CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 (Homo sapiens)	4 / 6	THR A2326 LEU A2324 THR A2281 LEU A2319	None	1.18A	4.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MVX_A_K4DA1304_0 (ION TRANSPORT PROTEIN)	6f9n	CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1 (Homo sapiens)	4 / 6	THR A 304 LEU A 303 THR A 314 LEU A 322	None	0.98A	undetectable