POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		1h4l CELL DIVISION
PROTEIN KINASE 5
(Homo
sapiens)		5 / 11LEU A 267
ARG A 274
ILE A 215
LEU A 173
ASP A 171
None
1.19A19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		2can ORNITHINE
AMINOTRANSFERASE
(Homo
sapiens)		5 / 11LEU A 360
LEU A 363
VAL A 367
ILE A 432
LEU A 397
None
1.19A22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		2x4f MYOSIN LIGHT CHAIN
KINASE FAMILY MEMBER
4
(Homo
sapiens)		5 / 11VAL A 154
ILE A 245
ALA A 251
LEU A 228
ASP A 285
None
1.19A21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		3hhc INTERLEUKIN-28B
(Homo
sapiens)		5 / 11LEU A  72
LEU A  86
GLN A  88
ALA A  19
LEU A 149
None
None
None
IOD  A 164 ( 4.0A)
None
1.18A16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		3hhd FATTY ACID SYNTHASE
(Homo
sapiens)		5 / 11LEU A 404
ARG A 405
VAL A 282
ILE A 246
ALA A 280
None
1.17A21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		3pta DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1
(Homo
sapiens)		5 / 11LEU A1299
VAL A1306
GLN A1308
ILE A1588
LEU A1151
None
None
None
None
SAH  A1601 (-3.6A)
1.13A18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		4qgk FATTY ALDEHYDE
DEHYDROGENASE
(Homo
sapiens)		5 / 11LEU A  27
LEU A  30
VAL A  34
GLN A  35
ASP A  69
None
1.16A23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		4qxe LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4, LINKER,
VARIABLE LYMPHOCYTE
RECEPTOR B
(Eptatretus
burgeri;
Homo
sapiens)		5 / 11LEU A  48
GLN A  71
ILE A  64
ALA A  76
LEU A  86
None
1.20A21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		4u1r ATP-DEPENDENT
6-PHOSPHOFRUCTOKINAS
E, PLATELET TYPE
(Homo
sapiens)		5 / 11LEU A 114
ARG A 117
GLN A 116
ILE A  60
ASP A  69
None
1.18A23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		5of4 TFIIH BASAL
TRANSCRIPTION FACTOR
COMPLEX HELICASE XPD
SUBUNIT
(Homo
sapiens)		5 / 11LEU B 107
LEU B 105
ALA B 172
LEU B 183
ASP B 179
None
1.15A22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		5oom 39S RIBOSOMAL
PROTEIN L23,
MITOCHONDRIAL
39S RIBOSOMAL
PROTEIN L47,
MITOCHONDRIAL
(Homo
sapiens)		5 / 11LEU Y 106
ARG U  21
VAL U  19
ALA U   2
ASP Y 143
None
1.20A17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		5xdr PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE DHX15
(Homo
sapiens)		5 / 11LEU A 259
LEU A 272
ILE A 257
PHE A 304
LEU A 286
None
1.19A20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens)		4 / 6ILE A 230
SER A 318
ARG A 261
PHE A 289
None
0.79A19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		1nub BASEMENT MEMBRANE
PROTEIN BM-40
(Homo
sapiens)		4 / 6ILE A 129
SER A 105
ILE A  88
PHE A  91
None
1.12A18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		1svc PROTEIN (NUCLEAR
FACTOR KAPPA-B
(NF-KB))
(Homo
sapiens)		4 / 6ILE P 253
SER P 343
ARG P 284
PHE P 314
None
0.91A21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		1v5w MEIOTIC
RECOMBINATION
PROTEIN DMC1/LIM15
HOMOLOG
(Homo
sapiens)		4 / 6ILE A 315
SER A 318
ILE A 116
PHE A 108
None
0.96A21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		3b2r CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
(Homo
sapiens)		4 / 6ILE A 599
ARG A 577
ILE A 556
PHE A 619
None
1.10A20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		3bjc CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
(Homo
sapiens)		4 / 6ILE A 599
ARG A 577
ILE A 556
PHE A 619
None
1.12A19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		3rw7 NUCLEAR RNA EXPORT
FACTOR 1
(Homo
sapiens)		4 / 6ILE A 286
SER A 285
ARG A 258
ILE A 259
None
1.11A19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		4ntj P2Y PURINOCEPTOR
12,SOLUBLE
CYTOCHROME B562,P2Y
PURINOCEPTOR 12
(Escherichia
coli;
Homo
sapiens)		4 / 6ILE A  61
SER A  55
ILE A  68
PHE A 114
None
1.10A21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		5exr DNA POLYMERASE ALPHA
CATALYTIC SUBUNIT
(Homo
sapiens)		4 / 6ILE C 629
ARG C 664
ILE C 662
PHE C 622
None
0.97A18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		5iud DNA POLYMERASE ALPHA
CATALYTIC SUBUNIT
(Homo
sapiens)		4 / 6ILE A 629
ARG A 664
ILE A 662
PHE A 622
None
1.02A20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		5mp0 M7GPPPN-MRNA
HYDROLASE
(Homo
sapiens)		4 / 6ILE D 176
ARG D 233
ILE D 232
PHE D 126
None
1.07A17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		5okl AFAMIN
(Homo
sapiens)		4 / 6ILE A 219
SER A 223
ARG A 339
ARG A 340
None
0.99A9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		1u0n PLATELET
GLYCOPROTEIN IB
(Homo
sapiens)		4 / 7LEU D 167
LEU D 153
LEU D 150
LEU D 115
None
0.72A17.62
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		2bex RIBONUCLEASE
INHIBITOR
(Homo
sapiens)		4 / 7LEU A 360
VAL A 319
LEU A 345
LEU A 342
None
0.62A12.09
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		2id5 LEUCINE RICH REPEAT
NEURONAL 6A
(Homo
sapiens)		5 / 7LEU A 172
VAL A 135
LEU A 157
LEU A 154
LEU A 119
None
0.70A10.93
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens)		4 / 7ILE A 255
LEU A 258
VAL A 128
LEU A 145
None
0.72A15.49
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		2qqk NEUROPILIN-2
(Homo
sapiens)		4 / 7VAL A 407
LEU A 339
LEU A 398
LEU A 422
None
0.70A10.04
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		3e4e CYTOCHROME P450 2E1
(Homo
sapiens)		4 / 7LEU A 455
LEU A 312
LEU A 487
LEU A 154
None
0.72A11.42
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		3o5d PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
(Homo
sapiens)		4 / 7LEU A 142
VAL A 245
LEU A 217
LEU A 219
None
0.69A15.21
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		4glp MONOCYTE
DIFFERENTIATION
ANTIGEN CD14
(Homo
sapiens)		4 / 7ILE A 128
LEU A 106
LEU A 123
LEU A 168
None
0.68A13.09
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		4keg MALTOSE-BINDING
PERIPLASMIC/PALATE
LUNG AND NASAL
EPITHELIUM CLONE
FUSION PROTEIN
(Escherichia
coli;
Homo
sapiens)		4 / 7LEU A1234
VAL A1131
LEU A1055
LEU A1059
None
0.72A9.67
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		4oav PROTEIN (RNASE L)
(Homo
sapiens)		4 / 7ILE B 491
LEU B 501
LEU B 486
LEU B 577
None
0.66A7.78
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		4qds NEUROPILIN-2
(Homo
sapiens)		4 / 7VAL A 407
LEU A 339
LEU A 398
LEU A 422
None
0.71A18.42
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		5i7k BPI FOLD-CONTAINING
FAMILY A MEMBER 1
(Homo
sapiens)		4 / 7LEU A 234
VAL A 131
LEU A  55
LEU A  59
None
0.69A14.29
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		5iaa UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME 5
(Homo
sapiens)		4 / 7ILE A 216
VAL A  76
LEU A 179
LEU A 273
None
0.63A14.34
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		5xxi CYTOCHROME P450 2C9
(Homo
sapiens)		4 / 7LEU A 453
LEU A 310
LEU A 485
LEU A 152
None
0.71A9.72
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		1ex0 COAGULATION FACTOR
XIII A CHAIN
(Homo
sapiens)		4 / 5ARG A 715
ALA A 291
TYR A 718
GLN A 313
None
1.46A7.79
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		1tdh NEI ENDONUCLEASE
VIII-LIKE 1
(Homo
sapiens)		4 / 5ARG A 179
ALA A 180
TYR A 263
GLN A 272
None
1.23A11.75
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		2wfx HEDGEHOG-INTERACTING
PROTEIN
(Homo
sapiens)		4 / 5ALA B 436
TYR B 509
GLN B 467
ILE B 465
None
1.46A11.61
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		3gcw PROPROTEIN
CONVERTASE
SUBTILISIN/KEXIN
TYPE 9
(Homo
sapiens)		4 / 5ARG A 160
ALA A 420
GLN A 344
ILE A 424
None
1.25A9.96
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR
(Escherichia
coli;
Homo
sapiens)		4 / 5ALA A-273
TYR A-245
GLN A  -9
ILE A -11
None
1.46A10.23
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		3qj4 RENALASE
(Homo
sapiens)		4 / 5ARG A  22
ALA A  18
TYR A 118
ILE A 328
None
1.02A12.61
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		3zrh UBIQUITIN
THIOESTERASE ZRANB1
(Homo
sapiens)		4 / 5ARG A 405
TYR A 433
GLN A 395
ILE A 387
None
1.39A9.78
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		4mrm GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1
(Homo
sapiens)		4 / 5ARG A 336
ALA A  74
TYR A 354
ILE A 357
None
1.27A12.23
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		4z0v 2',5'-PHOSPHODIESTER
ASE 12
(Homo
sapiens)		4 / 5ALA A 344
TYR A 342
GLN A 574
ILE A 576
None
1.44A14.49
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		5itq ENDONUCLEASE 8-LIKE
1
(Homo
sapiens)		4 / 5ARG A 179
ALA A 180
TYR A 263
GLN A 272
None
1.21A14.18
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		5mvd DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL
(Homo
sapiens)		4 / 5ARG A 318
ALA A 322
TYR A 321
ILE A 330
ACT  A 405 (-3.8A)
None
None
None
1.47A12.43
14.01