POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	2bx6	XRP2 PROTEIN (Homo sapiens)	5 / 12	PHE A 117 CYH A 130 CYH A 131 THR A 170 VAL A 119	None	1.50A	18.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	2p54	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA (Homo sapiens)	12 / 12	PHE A 273 CYH A 275 CYH A 276 THR A 279 SER A 280 TYR A 314 VAL A 332 ILE A 354 MET A 355 HIS A 440 VAL A 444 TYR A 464	735 A 469 (-3.7A) 735 A 469 ( 4.0A) 735 A 469 (-2.9A) 735 A 469 (-3.6A) 735 A 469 (-2.8A) 735 A 469 (-3.9A) 735 A 469 (-3.8A) 735 A 469 (-3.7A) 735 A 469 (-2.9A) 735 A 469 (-4.0A) 735 A 469 ( 3.9A) 735 A 469 (-4.6A)	0.32A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	2p54	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA (Homo sapiens)	6 / 12	PHE A 273 CYH A 275 CYH A 276 TYR A 464 ILE A 354 HIS A 440	735 A 469 (-3.7A) 735 A 469 ( 4.0A) 735 A 469 (-2.9A) 735 A 469 (-4.6A) 735 A 469 (-3.7A) 735 A 469 (-4.0A)	1.47A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	2p54	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA (Homo sapiens)	5 / 12	TYR A 314 VAL A 324 MET A 355 HIS A 440 TYR A 464	735 A 469 (-3.9A) None 735 A 469 (-2.9A) 735 A 469 (-4.0A) 735 A 469 (-4.6A)	1.50A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	2yu6	YTH DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	5 / 12	PHE A 62 VAL A 91 ILE A 12 MET A 13 VAL A 117	None	1.46A	18.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	3b0q	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA (Homo sapiens)	5 / 12	CYH A 285 SER A 289 MET A 364 HIS A 449 TYR A 473	MC5 A 1 (-3.6A) MC5 A 1 (-2.6A) MC5 A 1 (-3.7A) MC5 A 1 (-3.9A) MC5 A 1 (-4.9A)	0.75A	59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	3d5f	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA (Homo sapiens)	6 / 12	PHE A 282 CYH A 285 THR A 288 ILE A 363 HIS A 449 TYR A 473	L41 A 501 ( 4.9A) L41 A 501 (-3.5A) L41 A 501 (-3.0A) L41 A 501 ( 4.4A) L41 A 501 (-3.9A) L41 A 501 (-4.8A)	0.90A	70.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	3d5f	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA (Homo sapiens)	6 / 12	PHE A 282 CYH A 285 THR A 288 VAL A 341 HIS A 449 TYR A 473	L41 A 501 ( 4.9A) L41 A 501 (-3.5A) L41 A 501 (-3.0A) L41 A 501 ( 4.4A) L41 A 501 (-3.9A) L41 A 501 (-4.8A)	0.51A	70.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	3dzu	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA (Homo sapiens)	5 / 12	PHE D 282 SER D 289 MET D 364 HIS D 449 TYR D 473	None PLB D 701 ( 3.9A) PLB D 701 ( 4.8A) None None	0.70A	43.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	3f70	LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE 2 PROTEIN (Homo sapiens)	5 / 12	CYH A 368 TYR A 357 VAL A 348 ILE A 375 VAL A 332	None	1.41A	20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	4nge	PRESEQUENCE PROTEASE, MITOCHONDRIAL (Homo sapiens)	5 / 12	THR D 144 VAL D 90 HIS D 457 VAL D 297 TYR D 231	None	1.34A	13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	5j68	ASTROTACTIN-2 (Homo sapiens)	5 / 12	SER A1099 TYR A1101 ILE A1262 VAL A1047 TYR A1050	None	1.38A	19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	1e51	DELTA-AMINOLEVULINIC ACID DEHYDRATASE (Homo sapiens)	5 / 12	LEU A 61 PHE A 79 ILE A 314 LEU A 73 TYR A 196	None	1.15A	23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	1ikt	ESTRADIOL 17 BETA-DEHYDROGENASE 4 (Homo sapiens)	5 / 12	THR A 70 THR A 71 HIS A 37 LEU A 110 VAL A 30	None None None OXN A 123 ( 4.9A) None	1.14A	18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	2dhj	RHO GTPASE ACTIVATING PROTEIN 21 (Homo sapiens)	5 / 12	CYH A 71 THR A 90 THR A 89 LEU A 47 ILE A 112	None	1.30A	17.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	2p54	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA (Homo sapiens)	5 / 12	LEU A 247 CYH A 276 THR A 279 ILE A 317 ILE A 354	None 735 A 469 (-2.9A) 735 A 469 (-3.6A) 735 A 469 ( 4.8A) 735 A 469 (-3.7A)	1.07A	70.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	2p54	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA (Homo sapiens)	7 / 12	LEU A 247 PHE A 273 CYH A 276 THR A 279 ILE A 317 HIS A 440 TYR A 464	None 735 A 469 (-3.7A) 735 A 469 (-2.9A) 735 A 469 (-3.6A) 735 A 469 ( 4.8A) 735 A 469 (-4.0A) 735 A 469 (-4.6A)	1.32A	70.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	2p54	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA (Homo sapiens)	7 / 12	LEU A 258 PHE A 273 CYH A 276 THR A 279 ILE A 317 HIS A 440 TYR A 464	None 735 A 469 (-3.7A) 735 A 469 (-2.9A) 735 A 469 (-3.6A) 735 A 469 ( 4.8A) 735 A 469 (-4.0A) 735 A 469 (-4.6A)	1.27A	70.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	2pa1	PDZ AND LIM DOMAIN PROTEIN 2 (Homo sapiens)	5 / 12	THR A 30 LEU A 78 VAL A 7 ILE A 69 HIS A 62	None	1.10A	15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	2x8a	NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE (Homo sapiens)	5 / 12	PHE A 679 ILE A 730 LEU A 705 VAL A 663 ILE A 720	None	1.19A	24.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3b0q	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA (Homo sapiens)	5 / 12	PHE A 282 CYH A 285 HIS A 323 ILE A 326 TYR A 473	MC5 A 1 (-4.4A) MC5 A 1 (-3.6A) MC5 A 1 (-3.8A) MC5 A 1 ( 4.9A) MC5 A 1 (-4.9A)	0.86A	61.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3b0q	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA (Homo sapiens)	5 / 12	PHE A 282 CYH A 285 ILE A 326 HIS A 449 TYR A 473	MC5 A 1 (-4.4A) MC5 A 1 (-3.6A) MC5 A 1 ( 4.9A) MC5 A 1 (-3.9A) MC5 A 1 (-4.9A)	1.19A	61.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3d5f	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA (Homo sapiens)	12 / 12	LEU A 255 PHE A 282 CYH A 285 THR A 288 THR A 289 HIS A 323 ILE A 326 LEU A 339 VAL A 348 ILE A 364 HIS A 449 TYR A 473	None L41 A 501 ( 4.9A) L41 A 501 (-3.5A) L41 A 501 (-3.0A) L41 A 501 (-3.5A) L41 A 501 (-3.8A) None L41 A 501 (-4.8A) None L41 A 501 ( 4.2A) L41 A 501 (-3.9A) L41 A 501 (-4.8A)	0.96A	99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3dzu	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA (Homo sapiens)	5 / 12	LEU D 255 PHE D 282 ILE D 326 HIS D 449 TYR D 473	None None PLB D 701 ( 4.5A) None None	1.30A	42.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3j7y	MS30 (Homo sapiens)	5 / 12	LEU s 118 PHE s 367 THR s 297 LEU s 332 ILE s 361	None	1.18A	22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3jzy	INTERSECTIN 2 (Homo sapiens)	5 / 12	LEU A1604 CYH A1566 THR A1577 ILE A1580 VAL A1656	None None UNX A 2 ( 4.7A) None None	1.29A	21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3lm5	SERINE/THREONINE-PRO TEIN KINASE 17B (Homo sapiens)	5 / 12	LEU A 64 PHE A 180 ILE A 118 VAL A 47 ILE A 94	None None None QUE A 1 ( 4.6A) QUE A 1 (-4.6A)	1.12A	25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3pv6	IG-LIKE DOMAIN-CONTAINING PROTEIN DKFZP686O24166/DKFZP 686I21167 (Homo sapiens)	5 / 12	LEU A 147 THR A 224 THR A 181 LEU A 215 ILE A 190	None	1.12A	23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	4gl2	INTERFERON-INDUCED HELICASE C DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 12	CYH A 328 THR A 488 ILE A 814 LEU A 509 ILE A 858	None	1.29A	16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	4ol0	TRANSPORTIN-3 (Homo sapiens)	5 / 12	LEU B 232 THR B 323 ILE B 310 LEU B 253 VAL B 249	None	1.26A	14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	4oya	ADENYLATE CYCLASE TYPE 10 (Homo sapiens)	5 / 12	CYH A 122 ILE A 115 LEU A 147 VAL A 187 TYR A 240	None	1.19A	19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	5b25	CALCIUM/CALMODULIN-D EPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1B (Homo sapiens)	5 / 12	THR A 189 ILE A 194 LEU A 253 VAL A 245 TYR A 150	None	1.15A	21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	5v1b	EGL NINE HOMOLOG 2 (Homo sapiens)	5 / 12	PHE A 350 CYH A 310 THR A 371 VAL A 263 ILE A 308	None	1.18A	20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	5zal	ENDORIBONUCLEASE DICER (Homo sapiens)	5 / 12	CYH A 63 THR A 206 HIS A 178 VAL A 594 ILE A 223	None	1.23A	16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	6fuz	KINESIN LIGHT CHAIN 1,KINESIN LIGHT CHAIN 1,C-JUN-AMINO-TERMIN AL KINASE-INTERACTING PROTEIN 1 NANOBODY (Homo sapiens; Lama; Mus musculus)	5 / 12	PHE N 27 THR N 53 ILE N 51 LEU A 366 VAL A 380	None	0.90A	12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	1e51	DELTA-AMINOLEVULINIC ACID DEHYDRATASE (Homo sapiens)	5 / 12	LEU A 61 PHE A 79 ILE A 314 LEU A 73 TYR A 196	None	1.15A	23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	1htr	GASTRICSIN (Homo sapiens)	5 / 12	LEU B 278 VAL B 307 PHE B 308 THR B 261 LEU B 233	None	1.21A	19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	1ikt	ESTRADIOL 17 BETA-DEHYDROGENASE 4 (Homo sapiens)	5 / 12	THR A 70 THR A 71 HIS A 37 LEU A 110 VAL A 30	None None None OXN A 123 ( 4.9A) None	1.17A	18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	2nsm	CARBOXYPEPTIDASE N CATALYTIC CHAIN (Homo sapiens)	5 / 12	LEU A 359 VAL A 190 PHE A 189 THR A 101 TYR A 29	None	1.20A	19.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	2p54	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA (Homo sapiens)	7 / 12	LEU A 247 PHE A 273 CYH A 276 THR A 279 ILE A 317 HIS A 440 TYR A 464	None 735 A 469 (-3.7A) 735 A 469 (-2.9A) 735 A 469 (-3.6A) 735 A 469 ( 4.8A) 735 A 469 (-4.0A) 735 A 469 (-4.6A)	1.31A	70.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	2p54	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA (Homo sapiens)	7 / 12	LEU A 258 PHE A 273 CYH A 276 THR A 279 ILE A 317 HIS A 440 TYR A 464	None 735 A 469 (-3.7A) 735 A 469 (-2.9A) 735 A 469 (-3.6A) 735 A 469 ( 4.8A) 735 A 469 (-4.0A) 735 A 469 (-4.6A)	1.29A	70.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3a62	RIBOSOMAL PROTEIN S6 KINASE BETA-1 (Homo sapiens)	5 / 12	LEU A 323 VAL A 346 HIS A 208 ILE A 155 LEU A 219	None	1.28A	22.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3b0q	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA (Homo sapiens)	5 / 12	PHE A 282 CYH A 285 HIS A 323 ILE A 326 TYR A 473	MC5 A 1 (-4.4A) MC5 A 1 (-3.6A) MC5 A 1 (-3.8A) MC5 A 1 ( 4.9A) MC5 A 1 (-4.9A)	0.88A	61.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3b0q	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA (Homo sapiens)	5 / 12	PHE A 282 CYH A 285 ILE A 326 HIS A 449 TYR A 473	MC5 A 1 (-4.4A) MC5 A 1 (-3.6A) MC5 A 1 ( 4.9A) MC5 A 1 (-3.9A) MC5 A 1 (-4.9A)	1.14A	61.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3d5f	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA (Homo sapiens)	12 / 12	LEU A 255 VAL A 281 PHE A 282 CYH A 285 THR A 288 THR A 289 HIS A 323 ILE A 326 LEU A 339 VAL A 348 HIS A 449 TYR A 473	None L41 A 501 ( 4.7A) L41 A 501 ( 4.9A) L41 A 501 (-3.5A) L41 A 501 (-3.0A) L41 A 501 (-3.5A) L41 A 501 (-3.8A) None L41 A 501 (-4.8A) None L41 A 501 (-3.9A) L41 A 501 (-4.8A)	0.97A	99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3dzu	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA (Homo sapiens)	5 / 12	LEU D 255 PHE D 282 ILE D 326 HIS D 449 TYR D 473	None None PLB D 701 ( 4.5A) None None	1.29A	42.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3fy7	CHLORIDE INTRACELLULAR CHANNEL PROTEIN 3 (Homo sapiens)	5 / 12	VAL A 108 HIS A 21 ILE A 225 LEU A 206 VAL A 202	None	0.96A	25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	4rh7	GREEN FLUORESCENT PROTEIN/CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1 (Homo sapiens; synthetic construct)	5 / 12	LEU A4232 VAL A4286 THR A4282 LEU A4220 VAL A4245	None	1.18A	6.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	5b25	CALCIUM/CALMODULIN-D EPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1B (Homo sapiens)	5 / 12	THR A 189 ILE A 194 LEU A 253 VAL A 245 TYR A 150	None	1.17A	21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	5hdt	SISTER CHROMATID COHESION PROTEIN PDS5 HOMOLOG B (Homo sapiens)	5 / 12	VAL A 39 PHE A 42 HIS A 97 ILE A 106 LEU A 131	None	1.20A	14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	5k1b	WD REPEAT-CONTAINING PROTEIN 48 (Homo sapiens)	5 / 12	VAL B 132 THR B 161 THR B 160 LEU B 113 VAL B 99	None	1.11A	18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	5nn8	LYSOSOMAL ALPHA-GLUCOSIDASE (Homo sapiens)	5 / 12	VAL A 211 THR A 234 THR A 235 LEU A 169 VAL A 171	None None NAG A1004 ( 4.2A) None None	0.85A	16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	5uuu	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	5 / 12	LEU A 424 VAL A 447 HIS A 307 ILE A 254 LEU A 318	None	1.26A	20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	6fuz	KINESIN LIGHT CHAIN 1,KINESIN LIGHT CHAIN 1,C-JUN-AMINO-TERMIN AL KINASE-INTERACTING PROTEIN 1 NANOBODY (Homo sapiens; Lama; Mus musculus)	5 / 12	PHE N 27 THR N 53 ILE N 51 LEU A 366 VAL A 380	None	0.87A	12.37