POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_B_HFZB800_1 (GLUTAMATE RECEPTOR 2)	2jbh	PHOSPHORIBOSYLTRANSF ERASE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 10	SER A  93 LEU A 138 ILE A  64 SER A 101 GLY A  65	None	1.40A	22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_B_HFZB800_1 (GLUTAMATE RECEPTOR 2)	3ihj	ALANINE AMINOTRANSFERASE 2 (Homo sapiens)	5 / 10	LYS A  85 PRO A  86 LEU A  79 ILE A  75 GLY A 475	None	1.32A	18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_B_HFZB800_1 (GLUTAMATE RECEPTOR 2)	4asi	ACETYL-COA CARBOXYLASE 1 (Homo sapiens)	5 / 10	PRO A1948 LEU A2260 ILE A2018 PRO A2019 GLY A2017	None	1.44A	17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_B_HFZB800_1 (GLUTAMATE RECEPTOR 2)	4j1y	COMPLEMENT C1S SUBCOMPONENT (Homo sapiens)	5 / 10	PRO A 373 SER A 380 ILE A 361 PRO A 362 GLY A 360	None	1.38A	22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_B_HFZB800_1 (GLUTAMATE RECEPTOR 2)	4r7a	HISTONE-BINDING PROTEIN RBBP4 (Homo sapiens)	5 / 10	SER B 280 LEU B 306 ILE B 254 SER B 234 GLY B 244	None	1.34A	19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_B_HFZB800_1 (GLUTAMATE RECEPTOR 2)	5dot	CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL (Homo sapiens)	5 / 10	PRO A 268 LEU A 274 ILE A 299 SER A 294 GLY A 296	None	1.44A	11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_B_HFZB800_1 (GLUTAMATE RECEPTOR 2)	5kc8	GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 (Homo sapiens)	5 / 10	SER A 354 LEU A  93 ILE A  90 SER A 352 GLY A  89	None	1.38A	19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_B_HFZB800_1 (GLUTAMATE RECEPTOR 2)	5nkn	NEUTROPHIL GELATINASE-ASSOCIATE D LIPOCALIN (Homo sapiens)	5 / 10	PRO A  11 ILE A   8 SER A 158 SER A 156 GLY A 160	None	1.42A	14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_E_HFZE800_1 (GLUTAMATE RECEPTOR 2)	2jbh	PHOSPHORIBOSYLTRANSF ERASE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 11	ILE A  64 SER A 101 GLY A  65 SER A  93 LEU A 138	None	1.38A	22.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ILU_E_HFZE800_1 (GLUTAMATE RECEPTOR 2)	2zns	GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1 (Homo sapiens)	5 / 11	ILE A 504 PRO A 517 SER A 746 LYS A 747 GLY A 748	None	0.64A	51.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_E_HFZE800_1 (GLUTAMATE RECEPTOR 2)	3ihj	ALANINE AMINOTRANSFERASE 2 (Homo sapiens)	5 / 11	ILE A  75 GLY A 475 LYS A  85 PRO A  86 LEU A  79	None	1.32A	18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_E_HFZE800_1 (GLUTAMATE RECEPTOR 2)	3mos	TRANSKETOLASE (Homo sapiens)	5 / 11	ILE A 248 SER A  43 SER A  40 GLY A 245 LEU A 262	None TPP  A 700 ( 4.3A) TPP  A 700 (-2.5A) None None	1.21A	20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_E_HFZE800_1 (GLUTAMATE RECEPTOR 2)	4j1y	COMPLEMENT C1S SUBCOMPONENT (Homo sapiens)	5 / 11	ILE A 361 PRO A 362 GLY A 360 PRO A 373 SER A 380	None	1.39A	22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_E_HFZE800_1 (GLUTAMATE RECEPTOR 2)	4r7a	HISTONE-BINDING PROTEIN RBBP4 (Homo sapiens)	5 / 11	ILE B 254 SER B 234 GLY B 244 SER B 280 LEU B 306	None	1.27A	19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_E_HFZE800_1 (GLUTAMATE RECEPTOR 2)	5kc8	GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 (Homo sapiens)	5 / 11	ILE A  90 SER A 352 GLY A  89 SER A 354 LEU A  93	None	1.33A	19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	1fgg	GLUCURONYLTRANSFERAS E I (Homo sapiens)	4 / 5	PRO A 250 SER A 246 LEU A 285 SER A 286	None	1.46A	19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	1jm7	BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN (Homo sapiens)	4 / 5	LYS A  45 SER A  80 LEU A  73 SER A  36	None	1.37A	19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	1k4q	GLUTATHIONE REDUCTASE (Homo sapiens)	4 / 5	PRO A 169 SER A 166 LEU A 173 SER A 172	None	1.41A	20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	1nug	PROTEIN-GLUTAMINE GLUTAMYLTRANSFERASE E (Homo sapiens)	4 / 5	LYS A 505 SER A 541 LEU A 507 SER A 481	None	1.24A	16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	1soj	CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE B (Homo sapiens)	4 / 5	PRO A 756 SER A 793 LEU A 802 SER A 803	None	1.24A	20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	2doc	NEURAL CELL ADHESION MOLECULE 2 (Homo sapiens)	4 / 5	PRO A 112 SER A 114 LEU A  29 SER A  30	None	1.48A	25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	3bfn	KINESIN-LIKE PROTEIN KIF22 (Homo sapiens)	4 / 5	LYS A 213 PRO A 214 SER A 216 LEU A 188	None	1.48A	19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	3v4p	INTEGRIN ALPHA-4 (Homo sapiens)	4 / 5	PRO A 358 SER A 400 LEU A 363 SER A 395	None	1.17A	18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	3w8h	SERINE/THREONINE-PRO TEIN KINASE 25 (Homo sapiens)	4 / 5	LYS B  -2 PRO B 398 SER B 396 SER B 401	None	1.13A	16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	4chl	PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL (Homo sapiens)	4 / 5	PRO A 137 SER A 106 LEU A 174 SER A 132	None	1.41A	19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	4eyc	CATHELICIDIN ANTIMICROBIAL PEPTIDE (Homo sapiens)	4 / 5	LYS A  75 PRO A  76 SER A  78 LEU A 114	None	1.18A	18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	4iej	DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 (Homo sapiens)	4 / 5	LYS A 133 PRO A 136 LEU A 169 SER A 164	None	1.46A	16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	4v2d	FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2 (Homo sapiens)	4 / 5	PRO A 179 SER A 160 LEU A 206 SER A 205	None	1.31A	21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	4zrq	TRANSCOBALAMIN-2 (Homo sapiens)	4 / 5	PRO A 229 SER A 227 LEU A 260 SER A 259	None CNC  A 501 (-3.2A) None None	1.39A	21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	5aj1	SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY B MEMBER 1 (Homo sapiens)	4 / 5	LYS A  13 PRO A  14 SER A  30 SER A  67	None	1.27A	18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	5anb	ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	4 / 5	LYS K 493 PRO K 494 SER K 489 LEU K 496	None	1.28A	13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	5gve	DNA TOPOISOMERASE 3-BETA-1 (Homo sapiens)	4 / 5	LYS A  10 PRO A  11 SER A  37 SER A  16	None	1.09A	19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	4 / 5	LYS A 169 PRO A 168 SER A 165 SER A 240	None	1.40A	22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	5jsb	INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1 (Homo sapiens)	4 / 5	PRO A 289 SER A 285 LEU A 179 SER A 183	None	1.23A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	5nfj	MITOCHONDRIAL RIBONUCLEASE P PROTEIN 1 (Homo sapiens)	4 / 5	PRO A 319 SER A 316 LEU A 323 SER A 322	None None None SAM  A 501 (-2.7A)	1.41A	14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_H_HFZH800_1 (GLUTAMATE RECEPTOR 2)	5viy	BG1 FAB LIGHT CHAIN (Homo sapiens)	4 / 5	LYS G 149 SER G 177 LEU G 154 SER G 156	None	1.49A	22.78