POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)		8 / 12ASN A 705
GLY A 708
GLN A 711
MET A 742
ARG A 752
CYH A 784
LEU A 873
PHE A 891
BHM  A   1 (-3.6A)
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
None
BHM  A   1 (-4.4A)
None
0.86A48.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)		10 / 12ASN A 719
GLY A 722
MET A 756
LEU A 763
ARG A 766
CYH A 798
LEU A 887
CYH A 891
THR A 894
PHE A 905
WOW  A   1 (-3.3A)
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.0A)
WOW  A   1 (-3.8A)
WOW  A   1 ( 4.1A)
WOW  A   1 (-4.0A)
WOW  A   1 (-3.5A)
WOW  A   1 (-3.9A)
WOW  A   1 (-4.6A)
0.56A52.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)		9 / 12GLY A 722
GLN A 725
MET A 756
LEU A 763
ARG A 766
CYH A 798
LEU A 887
CYH A 891
THR A 894
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.0A)
WOW  A   1 (-3.8A)
WOW  A   1 ( 4.1A)
WOW  A   1 (-4.0A)
WOW  A   1 (-3.5A)
WOW  A   1 (-3.9A)
0.75A52.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		3llm ATP-DEPENDENT RNA
HELICASE A
(Homo
sapiens)		5 / 12GLY A 462
GLN A 371
LEU A 368
LEU A 426
THR A 419
None
None
None
None
ADP  A 565 (-2.8A)
1.44A18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		4gqb PROTEIN ARGININE
N-METHYLTRANSFERASE
5
(Homo
sapiens)		5 / 12ASN A 112
GLY A 114
LEU A  86
LEU A 138
THR A 144
None
1.49A19.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)		5 / 12ASN A 564
GLY A 567
LEU A 627
THR A 739
PHE A 749
MOF  A 801 (-3.0A)
MOF  A 801 (-3.4A)
None
MOF  A 801 (-3.9A)
MOF  A 801 (-4.4A)
1.47A96.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)		7 / 12ASN A 564
GLY A 568
GLN A 570
MET A 601
CYH A 736
THR A 739
PHE A 749
MOF  A 801 (-3.0A)
None
MOF  A 801 (-2.9A)
MOF  A 801 (-3.7A)
MOF  A 801 (-3.7A)
MOF  A 801 (-3.9A)
MOF  A 801 (-4.4A)
1.06A96.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)		12 / 12MET A 560
ASN A 564
GLY A 567
GLN A 570
MET A 601
LEU A 608
ARG A 611
CYH A 643
LEU A 732
CYH A 736
THR A 739
PHE A 749
MOF  A 801 (-3.9A)
MOF  A 801 (-3.0A)
MOF  A 801 (-3.4A)
MOF  A 801 (-2.9A)
MOF  A 801 (-3.7A)
MOF  A 801 ( 4.6A)
MOF  A 801 (-4.2A)
MOF  A 801 ( 3.7A)
MOF  A 801 ( 4.2A)
MOF  A 801 (-3.7A)
MOF  A 801 (-3.9A)
MOF  A 801 (-4.4A)
0.29A96.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)		6 / 12MET A 560
ASN A 564
LEU A 621
CYH A 736
THR A 739
PHE A 749
MOF  A 801 (-3.9A)
MOF  A 801 (-3.0A)
None
MOF  A 801 (-3.7A)
MOF  A 801 (-3.9A)
MOF  A 801 (-4.4A)
1.30A96.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)		9 / 12ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
CYH A 849
LEU A 938
CYH A 942
THR A 945
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.2A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
0.62A52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)		9 / 12ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
0.43A52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)		6 / 12ASN A 770
GLY A 774
GLN A 776
CYH A 942
THR A 945
PHE A 956
CV7  A1987 (-3.1A)
None
CV7  A1987 (-3.0A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
1.23A52.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		5kel C2G4 VARIABLE FAB
DOMAIN HEAVY CHAIN
EBOLA SURFACE
GLYCOPROTEIN, GP1
(Homo
sapiens;
Zaire
ebolavirus)		5 / 12ASN H  96
GLY H  95
LEU H  52
ARG H  71
THR A  42
None
1.50A18.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)		10 / 12ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
CYH A 849
LEU A 938
CYH A 942
THR A 945
PHE A 956
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.8A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
0.49A45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)		6 / 12ASN A 770
GLY A 774
GLN A 776
CYH A 942
THR A 945
PHE A 956
ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
1.18A45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_2
(GLUCOCORTICOID
RECEPTOR)		4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)		9 / 9LEU A 563
LEU A 566
TRP A 600
MET A 604
ALA A 605
MET A 639
GLN A 642
MET A 646
TYR A 735
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.6A)
None
None
MOF  A 801 ( 4.8A)
MOF  A 801 (-3.7A)
None
MOF  A 801 (-4.4A)
MOF  A 801 (-4.8A)
0.58A96.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)		8 / 12ASN A 705
GLY A 708
GLN A 711
MET A 742
ARG A 752
CYH A 784
LEU A 873
PHE A 891
BHM  A   1 (-3.6A)
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
None
BHM  A   1 (-4.4A)
None
0.88A48.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)		9 / 12ASN A 719
GLY A 722
MET A 756
ARG A 766
CYH A 798
LEU A 887
CYH A 891
THR A 894
PHE A 905
WOW  A   1 (-3.3A)
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 (-3.8A)
WOW  A   1 ( 4.1A)
WOW  A   1 (-4.0A)
WOW  A   1 (-3.5A)
WOW  A   1 (-3.9A)
WOW  A   1 (-4.6A)
0.55A52.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)		8 / 12GLY A 722
GLN A 725
MET A 756
ARG A 766
CYH A 798
LEU A 887
CYH A 891
THR A 894
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.1A)
WOW  A   1 (-3.8A)
WOW  A   1 ( 4.1A)
WOW  A   1 (-4.0A)
WOW  A   1 (-3.5A)
WOW  A   1 (-3.9A)
0.74A52.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)		6 / 12ASN A 564
GLY A 568
MET A 601
CYH A 736
THR A 739
PHE A 749
MOF  A 801 (-3.0A)
None
MOF  A 801 (-3.7A)
MOF  A 801 (-3.7A)
MOF  A 801 (-3.9A)
MOF  A 801 (-4.4A)
0.91A96.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)		12 / 12MET A 560
ASN A 564
GLY A 567
GLN A 570
MET A 601
ARG A 611
MET A 639
CYH A 643
LEU A 732
CYH A 736
THR A 739
PHE A 749
MOF  A 801 (-3.9A)
MOF  A 801 (-3.0A)
MOF  A 801 (-3.4A)
MOF  A 801 (-2.9A)
MOF  A 801 (-3.7A)
MOF  A 801 (-4.2A)
MOF  A 801 (-3.7A)
MOF  A 801 ( 3.7A)
MOF  A 801 ( 4.2A)
MOF  A 801 (-3.7A)
MOF  A 801 (-3.9A)
MOF  A 801 (-4.4A)
0.46A96.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)		7 / 12ASN A 770
GLN A 776
MET A 807
ARG A 817
CYH A 849
LEU A 938
THR A 945
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.2A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.1A)
0.71A52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)		8 / 12ASN A 770
GLN A 776
MET A 807
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
0.47A52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)		5 / 12ASN A 770
GLY A 774
CYH A 942
THR A 945
PHE A 956
CV7  A1987 (-3.1A)
None
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
0.95A52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)		9 / 12ASN A 770
GLN A 776
MET A 807
ARG A 817
CYH A 849
LEU A 938
CYH A 942
THR A 945
PHE A 956
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.8A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
0.54A45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)		5 / 12ASN A 770
GLY A 774
CYH A 942
THR A 945
PHE A 956
ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
0.86A45.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		1kmq TRANSFORMING PROTEIN
RHOA
(Homo
sapiens)		4 / 8LEU A  81
ALA A  56
LEU A  55
TYR A  74
None
0.91A21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		2kn6 APOPTOSIS-ASSOCIATED
SPECK-LIKE PROTEIN
CONTAINING A CARD
(Homo
sapiens)		4 / 8LEU A  12
MET A  81
ALA A  82
LEU A  85
None
0.92A21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		2mem SEX COMB ON
MIDLEG-LIKE PROTEIN
2
(Homo
sapiens)		4 / 8LEU A 379
ALA A 403
LEU A 371
GLN A 397
None
0.78A15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		2qna IMPORTIN SUBUNIT
BETA-1
(Homo
sapiens)		4 / 8ALA A 259
LEU A 260
MET A 256
ILE A 178
None
0.83A15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		3be8 NEUROLIGIN-4,
X-LINKED
(Homo
sapiens)		4 / 8LEU A 262
MET A 357
LEU A 356
ILE A 172
None
0.91A16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		3d3w L-XYLULOSE REDUCTASE
(Homo
sapiens)		4 / 8LEU B  79
ALA B 119
LEU B 122
ILE B 219
None
0.92A22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		3h6n PLEXIN-D1
(Homo
sapiens)		4 / 8LEU A1580
MET A1652
ALA A1651
LEU A1650
None
0.88A20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		3tad LIPRIN-ALPHA-2
(Homo
sapiens)		4 / 8LEU A1153
LEU A1138
TYR A1147
ILE A1156
None
0.94A22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		3thc BETA-GALACTOSIDASE
(Homo
sapiens)		4 / 8ALA A 290
LEU A 293
GLN A 355
ILE A 365
None
None
SO4  A1001 (-3.1A)
None
0.80A17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		4d10 COP9 SIGNALOSOME
COMPLEX SUBUNIT 6
(Homo
sapiens)		4 / 8LEU F  72
ALA F  42
LEU F  43
ILE F 146
None
0.89A22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		4kzy HUMAN INITIATION
FACTOR EIF1
(Homo
sapiens)		4 / 8ALA l 103
LEU l 102
GLN l  48
ILE l  35
None
0.91A16.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)		8 / 8LEU A 563
MET A 604
ALA A 605
LEU A 608
GLN A 642
MET A 646
TYR A 735
ILE A 747
MOF  A 801 (-3.9A)
None
MOF  A 801 ( 4.8A)
MOF  A 801 ( 4.6A)
None
MOF  A 801 (-4.4A)
MOF  A 801 (-4.8A)
MOF  A 801 ( 4.4A)
0.55A96.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		4r14 COP9 SIGNALOSOME
COMPLEX SUBUNIT 6
(Homo
sapiens)		4 / 8LEU A  72
ALA A  42
LEU A  43
ILE A 146
None
0.90A18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		5ccx TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRMT61A
TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
NON-CATALYTIC
SUBUNIT TRM6
(Homo
sapiens)		4 / 8ALA A  93
LEU A  94
TYR B 400
ILE B 180
None
0.72A20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		5lsk POLYAMINE-MODULATED
FACTOR 1
PROTEIN MIS12
HOMOLOG
(Homo
sapiens)		4 / 8LEU A 138
ALA B 168
LEU B 167
GLN B 161
None
0.80A23.08