POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P62_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		2a30 DEOXYCYTIDINE KINASE
(Homo
sapiens)		11 / 11ILE A  30
GLU A  53
VAL A  55
TRP A  58
MET A  85
TYR A  86
GLN A  97
ARG A 128
ASP A 133
PHE A 137
GLU A 197
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-3.0A)
None
None
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-3.2A)
DCZ  A 302 (-4.1A)
DCZ  A 302 (-3.2A)
DCZ  A 302 (-3.8A)
DCZ  A 302 (-3.5A)
0.48A94.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P62_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		2ocp DEOXYGUANOSINE
KINASE
(Homo
sapiens)		5 / 11GLU A  70
VAL A  72
TRP A  75
MET A  99
GLN A 111
None
DTP  A 301 (-4.1A)
None
DTP  A 301 ( 3.9A)
DTP  A 301 (-2.9A)
1.30A46.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P62_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		2ocp DEOXYGUANOSINE
KINASE
(Homo
sapiens)		7 / 11ILE A  47
VAL A  72
TRP A  75
MET A  99
TYR A 100
ASP A 147
PHE A 151
DTP  A 301 (-3.8A)
DTP  A 301 (-4.1A)
None
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.5A)
DTP  A 301 (-4.1A)
DTP  A 301 (-3.3A)
0.97A46.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P62_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		2ocp DEOXYGUANOSINE
KINASE
(Homo
sapiens)		9 / 11ILE A  47
VAL A  72
TRP A  75
MET A  99
TYR A 100
GLN A 111
ARG A 142
PHE A 151
GLU A 211
DTP  A 301 (-3.8A)
DTP  A 301 (-4.1A)
None
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.5A)
DTP  A 301 (-2.9A)
DTP  A 301 (-3.2A)
DTP  A 301 (-3.3A)
DTP  A 301 (-3.5A)
0.77A46.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P62_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		3tmp OTU
DOMAIN-CONTAINING
PROTEIN 5
(Homo
sapiens)		5 / 11GLU A 264
VAL A 262
MET A 252
ARG A 272
GLU A 284
None
None
None
SEP  A 177 ( 3.1A)
None
1.21A23.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		2a30 DEOXYCYTIDINE KINASE
(Homo
sapiens)		12 / 12ILE A  30
GLU A  53
VAL A  55
TRP A  58
LEU A  82
MET A  85
TYR A  86
PHE A  96
GLN A  97
ARG A 128
PHE A 137
GLU A 197
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-3.0A)
None
None
DCZ  A 302 ( 4.9A)
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-3.2A)
DCZ  A 302 (-4.1A)
DCZ  A 302 (-3.8A)
DCZ  A 302 (-3.5A)
0.48A92.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		2a30 DEOXYCYTIDINE KINASE
(Homo
sapiens)		7 / 12VAL A  55
TRP A  58
LEU A  82
MET A  85
PHE A  96
GLN A  97
GLU A 196
None
None
DCZ  A 302 ( 4.9A)
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-3.2A)
None
1.48A92.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		2ocp DEOXYGUANOSINE
KINASE
(Homo
sapiens)		6 / 12GLU A  70
VAL A  72
TRP A  75
MET A  99
PHE A 110
GLN A 111
None
DTP  A 301 (-4.1A)
None
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.2A)
DTP  A 301 (-2.9A)
1.18A44.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		2ocp DEOXYGUANOSINE
KINASE
(Homo
sapiens)		11 / 12ILE A  47
VAL A  72
TRP A  75
LEU A  96
MET A  99
TYR A 100
PHE A 110
GLN A 111
ARG A 142
PHE A 151
GLU A 211
DTP  A 301 (-3.8A)
DTP  A 301 (-4.1A)
None
DTP  A 301 (-4.6A)
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.5A)
DTP  A 301 (-4.2A)
DTP  A 301 (-2.9A)
DTP  A 301 (-3.2A)
DTP  A 301 (-3.3A)
DTP  A 301 (-3.5A)
0.69A44.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		2ocp DEOXYGUANOSINE
KINASE
(Homo
sapiens)		5 / 12VAL A  72
LEU A  96
MET A  99
TYR A 100
ARG A 118
DTP  A 301 (-4.1A)
DTP  A 301 (-4.6A)
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.5A)
DTP  A 301 (-3.1A)
1.45A44.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		3tac LIPRIN-ALPHA-2
(Homo
sapiens)		5 / 12ILE B 939
TRP B 906
LEU B 907
MET B 913
TYR B 917
None
1.12A23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		3tac LIPRIN-ALPHA-2
(Homo
sapiens)		5 / 12ILE B 943
VAL B 903
TRP B 906
LEU B 907
MET B 913
None
1.19A23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		3tad LIPRIN-ALPHA-2
(Homo
sapiens)		5 / 12ILE A 939
TRP A 906
LEU A 907
MET A 913
TYR A 917
None
1.11A22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		3tad LIPRIN-ALPHA-2
(Homo
sapiens)		5 / 12ILE A 943
VAL A 903
TRP A 906
LEU A 907
MET A 913
None
1.31A22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		6bbp CYTOHESIN-3,ADP-RIBO
SYLATION FACTOR 6
(Homo
sapiens;
Mus
musculus)		5 / 12GLU A 311
LEU A 388
TYR A 429
PHE A 384
GLU A 448
None
1.48A16.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		2a30 DEOXYCYTIDINE KINASE
(Homo
sapiens)		12 / 12ILE A  30
GLU A  53
VAL A  55
TRP A  58
LEU A  82
MET A  85
TYR A  86
PHE A  96
GLN A  97
ARG A 128
PHE A 137
GLU A 197
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-3.0A)
None
None
DCZ  A 302 ( 4.9A)
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-3.2A)
DCZ  A 302 (-4.1A)
DCZ  A 302 (-3.8A)
DCZ  A 302 (-3.5A)
0.46A92.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		2a30 DEOXYCYTIDINE KINASE
(Homo
sapiens)		7 / 12VAL A  55
TRP A  58
LEU A  82
MET A  85
PHE A  96
GLN A  97
GLU A 196
None
None
DCZ  A 302 ( 4.9A)
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-3.2A)
None
1.43A92.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		2ocp DEOXYGUANOSINE
KINASE
(Homo
sapiens)		5 / 12GLU A  70
VAL A  72
TRP A  75
PHE A 110
GLN A 111
None
DTP  A 301 (-4.1A)
None
DTP  A 301 (-4.2A)
DTP  A 301 (-2.9A)
1.05A44.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		2ocp DEOXYGUANOSINE
KINASE
(Homo
sapiens)		11 / 12ILE A  47
VAL A  72
TRP A  75
LEU A  96
MET A  99
TYR A 100
PHE A 110
GLN A 111
ARG A 142
PHE A 151
GLU A 211
DTP  A 301 (-3.8A)
DTP  A 301 (-4.1A)
None
DTP  A 301 (-4.6A)
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.5A)
DTP  A 301 (-4.2A)
DTP  A 301 (-2.9A)
DTP  A 301 (-3.2A)
DTP  A 301 (-3.3A)
DTP  A 301 (-3.5A)
0.74A44.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		3tac LIPRIN-ALPHA-2
(Homo
sapiens)		5 / 12ILE B 943
VAL B 903
TRP B 906
LEU B 907
MET B 913
None
1.09A23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		3tad LIPRIN-ALPHA-2
(Homo
sapiens)		5 / 12ILE A 943
VAL A 903
TRP A 906
LEU A 907
MET A 913
None
1.20A22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		6bbp CYTOHESIN-3,ADP-RIBO
SYLATION FACTOR 6
(Homo
sapiens;
Mus
musculus)		5 / 12GLU A 311
LEU A 388
TYR A 429
PHE A 384
GLU A 448
None
1.46A16.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VPP_A_GEOA1210_1
(DEOXYNUCLEOSIDE
KINASE)		2a30 DEOXYCYTIDINE KINASE
(Homo
sapiens)		11 / 12ILE A  30
GLU A  53
VAL A  55
TRP A  58
MET A  85
TYR A  86
PHE A  96
GLN A  97
ARG A 128
PHE A 137
GLU A 197
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-3.0A)
None
None
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-3.2A)
DCZ  A 302 (-4.1A)
DCZ  A 302 (-3.8A)
DCZ  A 302 (-3.5A)
0.61A32.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VPP_A_GEOA1210_1
(DEOXYNUCLEOSIDE
KINASE)		2ocp DEOXYGUANOSINE
KINASE
(Homo
sapiens)		6 / 12GLU A  70
VAL A  72
TRP A  75
MET A  99
PHE A 110
GLN A 111
None
DTP  A 301 (-4.1A)
None
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.2A)
DTP  A 301 (-2.9A)
1.17A33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VPP_A_GEOA1210_1
(DEOXYNUCLEOSIDE
KINASE)		2ocp DEOXYGUANOSINE
KINASE
(Homo
sapiens)		10 / 12ILE A  47
VAL A  72
TRP A  75
MET A  99
TYR A 100
PHE A 110
GLN A 111
ARG A 142
PHE A 151
GLU A 211
DTP  A 301 (-3.8A)
DTP  A 301 (-4.1A)
None
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.5A)
DTP  A 301 (-4.2A)
DTP  A 301 (-2.9A)
DTP  A 301 (-3.2A)
DTP  A 301 (-3.3A)
DTP  A 301 (-3.5A)
0.75A33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_A_GEOA1210_1
(DEOXYNUCLEOSIDE
KINASE)		3tmp OTU
DOMAIN-CONTAINING
PROTEIN 5
(Homo
sapiens)		5 / 12GLU A 264
VAL A 262
MET A 252
ARG A 272
GLU A 284
None
None
None
SEP  A 177 ( 3.1A)
None
1.30A22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_A_GEOA1210_1
(DEOXYNUCLEOSIDE
KINASE)		5zbq NEUROPEPTIDE Y
RECEPTOR TYPE 1,T4
LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens)		5 / 12ILE A 261
GLU A 137
TYR A 320
ARG A 138
ALA A 135
None
1.31A17.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VPP_B_GEOB1207_1
(DEOXYNUCLEOSIDE
KINASE)		2a30 DEOXYCYTIDINE KINASE
(Homo
sapiens)		11 / 12ILE A  30
GLU A  53
VAL A  55
TRP A  58
MET A  85
TYR A  86
PHE A  96
GLN A  97
ARG A 128
PHE A 137
GLU A 197
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-3.0A)
None
None
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-3.2A)
DCZ  A 302 (-4.1A)
DCZ  A 302 (-3.8A)
DCZ  A 302 (-3.5A)
0.62A32.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VPP_B_GEOB1207_1
(DEOXYNUCLEOSIDE
KINASE)		2ocp DEOXYGUANOSINE
KINASE
(Homo
sapiens)		7 / 12GLU A  70
VAL A  72
TRP A  75
MET A  99
PHE A 110
GLN A 111
PHE A 151
None
DTP  A 301 (-4.1A)
None
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.2A)
DTP  A 301 (-2.9A)
DTP  A 301 (-3.3A)
1.20A33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VPP_B_GEOB1207_1
(DEOXYNUCLEOSIDE
KINASE)		2ocp DEOXYGUANOSINE
KINASE
(Homo
sapiens)		10 / 12ILE A  47
VAL A  72
TRP A  75
MET A  99
TYR A 100
PHE A 110
GLN A 111
ARG A 142
PHE A 151
GLU A 211
DTP  A 301 (-3.8A)
DTP  A 301 (-4.1A)
None
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.5A)
DTP  A 301 (-4.2A)
DTP  A 301 (-2.9A)
DTP  A 301 (-3.2A)
DTP  A 301 (-3.3A)
DTP  A 301 (-3.5A)
0.73A33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_B_GEOB1207_1
(DEOXYNUCLEOSIDE
KINASE)		3tmp OTU
DOMAIN-CONTAINING
PROTEIN 5
(Homo
sapiens)		5 / 12GLU A 264
VAL A 262
MET A 252
ARG A 272
GLU A 284
None
None
None
SEP  A 177 ( 3.1A)
None
1.34A22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		1bhg BETA-GLUCURONIDASE
(Homo
sapiens)		5 / 12ALA A 493
LEU A 501
ASN A 450
PHE A 481
SER A 447
None
1.15A22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		1bjx PROTEIN DISULFIDE
ISOMERASE
(Homo
sapiens)		5 / 12GLY A 185
VAL A 203
LEU A 208
PHE A 144
ILE A 169
None
1.18A16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		1luj CATENIN BETA-1
(Homo
sapiens)		5 / 12GLY A 277
ALA A 276
ASN A 308
SER A 311
ILE A 314
None
1.18A23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		2z65 LYMPHOCYTE ANTIGEN
96
TOLL-LIKE RECEPTOR
4, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Homo
sapiens)		5 / 12GLY C 110
TYR C  42
GLU A  42
PHE A  63
ASN A  64
None
1.22A15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		3ll8 CALCINEURIN SUBUNIT
B TYPE 1
SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2B
CATALYTIC SUBUNIT
ALPHA ISOFORM
(Homo
sapiens)		5 / 12GLY B  77
GLN B  80
VAL B  57
LEU A 365
PHE B  93
None
1.24A15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		3she MAP KINASE-ACTIVATED
PROTEIN KINASE 3
(Homo
sapiens)		5 / 12GLY A 151
ALA A 153
LEU A 183
ASN A 171
ILE A 231
None
None
None
I85  A 350 (-4.4A)
None
1.15A20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		4cns DIHYDROPYRIMIDINASE-
LIKE 3
(Homo
sapiens)		5 / 12GLY A 276
VAL A 236
GLU A 232
SER A 282
ILE A 317
None
1.16A22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		5aiz ZINC FINGER MIZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens)		5 / 12GLY A  74
ALA A  64
VAL A  63
ASN A  24
PHE A  28
None
1.13A15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		5dgo CELL DIVISION
CONTROL PROTEIN 45
HOMOLOG
(Homo
sapiens)		5 / 12GLY A 223
GLN A 227
ALA A 199
LEU A 245
ILE A 233
None
1.14A21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		5ffo INTEGRIN BETA-6
(Homo
sapiens)		5 / 12GLY B 334
ALA B 312
VAL B 252
LEU B 138
ILE B 347
None
1.21A21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		5mrv CARBOXYPEPTIDASE O
(Homo
sapiens)		5 / 12GLY A  57
ALA A 197
VAL A 198
LEU A 127
ILE A 132
None
1.14A9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		5wdu BNAB NIH45-46 SCFV
HEAVY CHAIN
ENVELOPE
GLYCOPROTEIN GP160
(Homo
sapiens;
Human
immunodeficiency
virus
1)		5 / 12GLY D  55
VAL D  73
TYR D  74
LEU D  30
ASN G 425
None
None
NAG  G 617 (-4.2A)
None
None
1.16A10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		6ar2 SARCOLEMMAL
MEMBRANE-ASSOCIATED
PROTEIN
(Homo
sapiens)		5 / 12ALA A  44
VAL A  22
LEU A  24
PHE A   8
ILE A  97
None
1.25A10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		6bp2 ENVELOPE
GLYCOPROTEIN
MR191 FAB HEAVY
CHAIN
(Homo
sapiens;
Marburg
marburgvirus)		5 / 12GLY A 127
GLN A 128
TYR H  61
LEU H 110
SER H  56
None
1.15A12.53