POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_A_GAIA407_0 (PROTEIN (ARGINASE))	1kmq	TRANSFORMING PROTEIN RHOA (Homo sapiens)	4 / 6	ARG A 150 LEU A 114 MET A 147 ASP A 146	None	1.45A	23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_A_GAIA407_0 (PROTEIN (ARGINASE))	2c11	MEMBRANE COPPER AMINE OXIDASE (Homo sapiens)	4 / 6	ARG A 585 LEU A 562 MET A 544 ASP A 543	None	1.47A	16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_A_GAIA407_0 (PROTEIN (ARGINASE))	2dlu	INAD-LIKE PROTEIN (Homo sapiens)	4 / 6	ARG A  96 HIS A  62 LEU A  64 ASP A  61	None	1.23A	17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_A_GAIA407_0 (PROTEIN (ARGINASE))	2uw2	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE M2 SUBUNIT (Homo sapiens)	4 / 6	HIS A 269 GLU A 232 LEU A 145 ASP A 138	FE  A1351 (-3.5A) FE  A1351 (-3.4A) None None	1.43A	22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_A_GAIA407_0 (PROTEIN (ARGINASE))	3vpo	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE SUBUNIT M2 (Homo sapiens)	4 / 6	HIS A 269 GLU A 232 LEU A 145 ASP A 138	FE  A 402 (-3.3A) FE  A 402 (-2.8A) None None	1.41A	22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_A_GAIA407_0 (PROTEIN (ARGINASE))	4a14	KINESIN-LIKE PROTEIN KIF7 (Homo sapiens)	4 / 6	HIS A  31 GLU A  26 LEU A  22 ASP A 329	None	1.50A	23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_A_GAIA407_0 (PROTEIN (ARGINASE))	4wrn	MALTOSE-BINDING PERIPLASMIC PROTEIN,UROMODULIN (Escherichia coli; Homo sapiens)	4 / 6	ARG A 559 LEU A 601 MET A 590 ASP A 592	None	1.10A	18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_A_GAIA407_0 (PROTEIN (ARGINASE))	5u09	CANNABINOID RECEPTOR 1,GLGA GLYCOGEN SYNTHASE (Homo sapiens; Pyrococcus abyssi)	4 / 6	GLU A 273 LEU A 276 MET A 363 ASP A 366	None	1.50A	20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_A_GAIA407_0 (PROTEIN (ARGINASE))	5wu6	SPECKLE TARGETED PIP5K1A-REGULATED POLY(A) POLYMERASE (Homo sapiens)	4 / 6	ARG A 481 GLU A 401 LEU A 398 ASP A 478	None	1.28A	20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_C_GAIC409_0 (PROTEIN (ARGINASE))	2c11	MEMBRANE COPPER AMINE OXIDASE (Homo sapiens)	4 / 6	MET A 544 ASP A 543 ARG A 585 LEU A 562	None	1.47A	16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_C_GAIC409_0 (PROTEIN (ARGINASE))	2dlu	INAD-LIKE PROTEIN (Homo sapiens)	4 / 6	ASP A  61 ARG A  96 HIS A  62 LEU A  64	None	1.22A	17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_C_GAIC409_0 (PROTEIN (ARGINASE))	2uw2	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE M2 SUBUNIT (Homo sapiens)	4 / 6	ASP A 138 HIS A 269 GLU A 232 LEU A 145	None FE  A1351 (-3.5A) FE  A1351 (-3.4A) None	1.44A	22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_C_GAIC409_0 (PROTEIN (ARGINASE))	3ui7	CAMP AND CAMP-INHIBITED CGMP 3',5'-CYCLIC PHOSPHODIESTERASE 10A (Homo sapiens)	4 / 6	ASP A 566 ARG A 520 HIS A 567 LEU A 582	None	1.35A	20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_C_GAIC409_0 (PROTEIN (ARGINASE))	4a14	KINESIN-LIKE PROTEIN KIF7 (Homo sapiens)	4 / 6	ASP A 329 HIS A  31 GLU A  26 LEU A  22	None	1.50A	23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_C_GAIC409_0 (PROTEIN (ARGINASE))	4wrn	MALTOSE-BINDING PERIPLASMIC PROTEIN,UROMODULIN (Escherichia coli; Homo sapiens)	4 / 6	MET A 590 ASP A 592 ARG A 559 LEU A 601	None	1.07A	18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_C_GAIC409_0 (PROTEIN (ARGINASE))	5u09	CANNABINOID RECEPTOR 1,GLGA GLYCOGEN SYNTHASE (Homo sapiens; Pyrococcus abyssi)	4 / 6	MET A 363 ASP A 366 GLU A 273 LEU A 276	None	1.49A	20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_C_GAIC409_0 (PROTEIN (ARGINASE))	5wu6	SPECKLE TARGETED PIP5K1A-REGULATED POLY(A) POLYMERASE (Homo sapiens)	4 / 6	ASP A 478 ARG A 481 GLU A 401 LEU A 398	None	1.28A	20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_D_GAID410_0 (PROTEIN (ARGINASE))	1kmq	TRANSFORMING PROTEIN RHOA (Homo sapiens)	4 / 6	ARG A 150 LEU A 114 MET A 147 ASP A 146	None	1.42A	23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_D_GAID410_0 (PROTEIN (ARGINASE))	2c11	MEMBRANE COPPER AMINE OXIDASE (Homo sapiens)	4 / 6	ARG A 585 LEU A 562 MET A 544 ASP A 543	None	1.44A	16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_D_GAID410_0 (PROTEIN (ARGINASE))	2dlu	INAD-LIKE PROTEIN (Homo sapiens)	4 / 6	ARG A  96 HIS A  62 LEU A  64 ASP A  61	None	1.20A	17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_D_GAID410_0 (PROTEIN (ARGINASE))	2uw2	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE M2 SUBUNIT (Homo sapiens)	4 / 6	HIS A 269 GLU A 232 LEU A 145 ASP A 138	FE  A1351 (-3.5A) FE  A1351 (-3.4A) None None	1.43A	22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_D_GAID410_0 (PROTEIN (ARGINASE))	4a14	KINESIN-LIKE PROTEIN KIF7 (Homo sapiens)	4 / 6	HIS A  31 GLU A  26 LEU A  22 ASP A 329	None	1.49A	23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_D_GAID410_0 (PROTEIN (ARGINASE))	4wrn	MALTOSE-BINDING PERIPLASMIC PROTEIN,UROMODULIN (Escherichia coli; Homo sapiens)	4 / 6	ARG A 559 LEU A 601 MET A 590 ASP A 592	None	1.09A	18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_D_GAID410_0 (PROTEIN (ARGINASE))	5u09	CANNABINOID RECEPTOR 1,GLGA GLYCOGEN SYNTHASE (Homo sapiens; Pyrococcus abyssi)	4 / 6	GLU A 273 LEU A 276 MET A 363 ASP A 366	None	1.50A	20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_D_GAID410_0 (PROTEIN (ARGINASE))	5wu6	SPECKLE TARGETED PIP5K1A-REGULATED POLY(A) POLYMERASE (Homo sapiens)	4 / 6	ARG A 481 GLU A 401 LEU A 398 ASP A 478	None	1.27A	20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	1kmq	TRANSFORMING PROTEIN RHOA (Homo sapiens)	4 / 6	ARG A 150 LEU A 114 MET A 147 ASP A 146	None	1.43A	23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	1lt8	BETAINE-HOMOCYSTEINE METHYLTRANSFERASE (Homo sapiens)	4 / 6	ARG A 108 GLU A 113 LEU A  64 ASP A 112	None	1.41A	21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	2c11	MEMBRANE COPPER AMINE OXIDASE (Homo sapiens)	4 / 6	ARG A 585 LEU A 562 MET A 544 ASP A 543	None	1.47A	16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	2dlu	INAD-LIKE PROTEIN (Homo sapiens)	4 / 6	ARG A  96 HIS A  62 LEU A  64 ASP A  61	None	1.20A	17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	2j0u	ATP-DEPENDENT RNA HELICASE DDX48 PROTEIN CASC3 (Homo sapiens; Homo sapiens)	4 / 6	ARG A 206 HIS T 220 GLU T 219 ASP T 221	None	1.37A	21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	2uw2	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE M2 SUBUNIT (Homo sapiens)	4 / 6	HIS A 269 GLU A 232 LEU A 145 ASP A 138	FE  A1351 (-3.5A) FE  A1351 (-3.4A) None None	1.43A	22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	4a14	KINESIN-LIKE PROTEIN KIF7 (Homo sapiens)	4 / 6	HIS A  31 GLU A  26 LEU A  22 ASP A 329	None	1.50A	23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	4n0f	IGG RECEPTOR FCRN LARGE SUBUNIT P51 (Homo sapiens)	4 / 6	HIS A 248 GLU A 247 LEU A 196 ASP A 246	None	1.37A	21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	4wrn	MALTOSE-BINDING PERIPLASMIC PROTEIN,UROMODULIN (Escherichia coli; Homo sapiens)	4 / 6	ARG A 559 LEU A 601 MET A 590 ASP A 592	None	1.09A	18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	5anr	PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 (Homo sapiens)	4 / 6	ARG B 421 HIS B 420 LEU B 414 ASP B 392	None	1.45A	23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	5u09	CANNABINOID RECEPTOR 1,GLGA GLYCOGEN SYNTHASE (Homo sapiens; Pyrococcus abyssi)	4 / 6	GLU A 273 LEU A 276 MET A 363 ASP A 366	None	1.47A	20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	5wu6	SPECKLE TARGETED PIP5K1A-REGULATED POLY(A) POLYMERASE (Homo sapiens)	4 / 6	ARG A 481 GLU A 401 LEU A 398 ASP A 478	None	1.26A	20.66