POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J03_A_FVSA603_1 (BIFUNCTIONAL EPOXIDE HYDROLASE 2)	2iqc	FANCONI ANEMIA GROUP F PROTEIN (Homo sapiens)	5 / 12	PHE A 201 PHE A 251 LEU A 210 LEU A 259 LEU A 170	None	1.07A	17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J03_A_FVSA603_1 (BIFUNCTIONAL EPOXIDE HYDROLASE 2)	2uzx	HEPATOCYTE GROWTH FACTOR RECEPTOR (Homo sapiens)	5 / 12	PHE B 258 TYR B 260 PHE B 253 LEU B 296 LEU B 262	None	1.29A	20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J03_A_FVSA603_1 (BIFUNCTIONAL EPOXIDE HYDROLASE 2)	4fww	MACROPHAGE-STIMULATI NG PROTEIN RECEPTOR (Homo sapiens)	5 / 12	PHE A 258 TYR A 260 PHE A 253 LEU A 298 LEU A 262	None	1.28A	21.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4J03_A_FVSA603_1 (BIFUNCTIONAL EPOXIDE HYDROLASE 2)	4jnc	BIFUNCTIONAL EPOXIDE HYDROLASE 2 (Homo sapiens)	12 / 12	ASP A 335 TYR A 343 ILE A 363 PHE A 381 TYR A 383 PHE A 387 LEU A 408 LEU A 428 TYR A 466 LEU A 499 HIS A 524 TRP A 525	1LF  A 601 (-2.6A) None None 1LF  A 601 (-4.5A) 1LF  A 601 (-4.4A) None 1LF  A 601 (-4.5A) None 1LF  A 601 (-4.5A) 1LF  A 601 (-4.6A) 1LF  A 601 (-3.3A) None	0.62A	85.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J03_A_FVSA603_1 (BIFUNCTIONAL EPOXIDE HYDROLASE 2)	4k3j	HEPATOCYTE GROWTH FACTOR BETA CHAIN (Homo sapiens)	5 / 12	PHE B 258 TYR B 260 PHE B 253 LEU B 296 LEU B 262	None	1.31A	21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J03_A_FVSA603_1 (BIFUNCTIONAL EPOXIDE HYDROLASE 2)	4owt	INTEGRATOR COMPLEX SUBUNIT 3 (Homo sapiens)	5 / 12	TYR A 336 PHE A 332 LEU A 305 LEU A 349 LEU A 135	None	1.28A	21.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4J03_A_FVSA603_1 (BIFUNCTIONAL EPOXIDE HYDROLASE 2)	5all	SOLUBLE EPOXIDE HYDROLASE (Homo sapiens)	12 / 12	ASP A 335 TYR A 343 ILE A 363 PHE A 381 TYR A 383 PHE A 387 LEU A 408 LEU A 428 TYR A 466 LEU A 499 HIS A 524 TRP A 525	II6  A1552 ( 3.0A) None None None II6  A1552 (-4.2A) None None None SO4  A1550 ( 4.8A) SO4  A1550 (-4.8A) II6  A1552 (-3.6A) II6  A1552 ( 4.7A)	0.44A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J03_A_FVSA603_1 (BIFUNCTIONAL EPOXIDE HYDROLASE 2)	5dj4	SESTRIN-2 (Homo sapiens)	5 / 12	ILE A 216 LEU A 363 TYR A  89 LEU A 207 HIS A 203	None	1.25A	21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J03_A_FVSA603_1 (BIFUNCTIONAL EPOXIDE HYDROLASE 2)	6cer	PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA, SOMATIC FORM, MITOCHONDRIAL (Homo sapiens)	5 / 12	ILE A 317 PHE A  96 PHE A 131 LEU A 164 LEU A  85	None	1.34A	9.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4J03_A_FVSA603_2 (BIFUNCTIONAL EPOXIDE HYDROLASE 2)	4jnc	BIFUNCTIONAL EPOXIDE HYDROLASE 2 (Homo sapiens)	4 / 5	TRP A 336 SER A 374 GLN A 384 ASN A 472	1LF  A 601 (-3.4A) None 1LF  A 601 ( 4.1A) None	0.47A	85.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4J03_A_FVSA603_2 (BIFUNCTIONAL EPOXIDE HYDROLASE 2)	5all	SOLUBLE EPOXIDE HYDROLASE (Homo sapiens)	5 / 5	TRP A 336 SER A 374 GLN A 384 MET A 469 ASN A 472	SO4  A1550 (-3.3A) None None None None	0.39A	100.00