POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G1R_B_FITB327_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		3cav 3-OXO-5-BETA-STEROID
4-DEHYDROGENASE
(Homo
sapiens)		11 / 11TYR A  26
ILE A  57
TYR A  58
TRP A  89
GLU A 120
TYR A 132
ARG A 134
TRP A 140
TRP A 230
MET A 313
TRP A 314
CI2  A 328 ( 4.0A)
None
CI2  A 328 ( 4.5A)
None
CI2  A 328 (-4.6A)
None
None
None
CI2  A 328 (-4.2A)
CI2  A 328 (-4.0A)
None
0.33A94.22