POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQP_A_FCNA4002_1 (PROBABLE FOSFOMYCIN RESISTANCE PROTEIN)	5fzo	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	5 / 10	HIS A2336 GLU A2338 HIS A2466 THR A2333 TRP A2391	MN  A3499 (-3.4A) MN  A3499 (-2.5A) MN  A3499 (-3.4A) None None	1.20A	19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQP_B_FCNB4001_1 (PROBABLE FOSFOMYCIN RESISTANCE PROTEIN)	5fzo	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	5 / 10	HIS A2466 THR A2333 TRP A2391 HIS A2336 GLU A2338	MN  A3499 (-3.4A) None None MN  A3499 (-3.4A) MN  A3499 (-2.5A)	1.20A	19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BNN_A_FCNA1199_1 (EPOXIDASE)	4tnu	ASPARTOACYLASE (Homo sapiens)	5 / 9	TYR A 288 ASN A  70 HIS A  21 GLU A  24 HIS A 116	AS9  A 402 (-4.5A) AS9  A 402 (-4.0A) ZN  A 401 ( 3.2A) ZN  A 401 ( 2.1A) ZN  A 401 ( 3.4A)	1.36A	23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BNN_B_FCNB1199_1 (EPOXIDASE)	1h2t	80 KDA NUCLEAR CAP BINDING PROTEIN (Homo sapiens)	4 / 8	TYR C 202 LEU C 203 GLU C 227 HIS C 210	None	0.91A	14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BNN_B_FCNB1199_1 (EPOXIDASE)	2hgs	PROTEIN (GLUTATHIONE SYNTHETASE) (Homo sapiens)	4 / 8	TYR A 265 LEU A 208 GLU A 214 ALA A 210	None None GSH  A 503 (-2.4A) None	1.02A	18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BNN_B_FCNB1199_1 (EPOXIDASE)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	4 / 8	TYR A 218 LEU A 235 GLU A 139 ALA A 167	None	0.75A	18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BNN_B_FCNB1199_1 (EPOXIDASE)	3kz1	RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 11 (Homo sapiens)	4 / 8	LEU A 825 HIS A 749 GLU A 878 ALA A 829	None	0.82A	20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BNN_B_FCNB1199_1 (EPOXIDASE)	5kca	CEREBELLIN-1,CEREBEL LIN-1,CEREBELLIN-1,G LUTAMATE RECEPTOR IONOTROPIC, DELTA-2 (Homo sapiens)	4 / 8	LEU A 839 GLU A 215 HIS A 834 ALA A 837	None	0.96A	12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BNN_B_FCNB1199_1 (EPOXIDASE)	5l85	ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3 (Homo sapiens)	4 / 8	LEU A 126 HIS A 109 GLU A 133 ALA A 129	None	0.99A	16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BNN_B_FCNB1199_1 (EPOXIDASE)	5vhi	26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2 (Homo sapiens)	4 / 8	ASN f 565 HIS f 566 GLU f 574 ALA f 572	None	1.00A	12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BNN_B_FCNB1199_1 (EPOXIDASE)	6c01	ECTONUCLEOTIDE PYROPHOSPHATASE/PHOS PHODIESTERASE FAMILY MEMBER 3 (Homo sapiens)	4 / 8	TYR A 173 LEU A 342 GLU A 323 ALA A 341	None	1.03A	16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	1pja	PALMITOYL-PROTEIN THIOESTERASE 2 PRECURSOR (Homo sapiens)	4 / 8	GLY A 114 GLY A 113 GLY A  44 SER A 137	None	0.59A	22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	1zli	CARBOXYPEPTIDASE B (Homo sapiens)	4 / 8	GLY A 253 GLY A 252 ILE A 154 SER A 207	None	0.65A	21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	2esb	DUAL SPECIFICITY PROTEIN PHOSPHATASE 18 (Homo sapiens)	4 / 8	GLY A  32 GLY A 107 ILE A 140 SER A  18	None EPE  A1002 (-4.3A) None None	0.65A	20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	2wfi	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G (Homo sapiens)	4 / 8	GLY A  87 GLY A  86 GLY A  84 SER A 122	None	0.64A	19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	2x47	MACRO DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	4 / 8	GLY A 180 GLY A 185 HIS A 188 ILE A 187	None	0.69A	21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	2xjy	LIM DOMAIN-BINDING PROTEIN 1 RHOMBOTIN-2 (Homo sapiens)	4 / 8	GLY B 348 GLY B 347 ILE A 101 THR A 107	None	0.49A	9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	3l2p	DNA LIGASE 3 (Homo sapiens)	5 / 8	GLY A 699 ILE A 697 SER A 714 SER A 703 THR A 640	None	0.92A	19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	3max	HISTONE DEACETYLASE 2 (Homo sapiens)	5 / 8	GLY A 306 GLY A 305 GLY A 143 HIS A 145 ILE A 161	LLX  A 400 (-3.7A) LLX  A 400 (-3.5A) None LLX  A 400 (-4.0A) None	1.27A	20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	3njp	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	4 / 8	GLY A 315 GLY A 343 GLY A 379 ILE A 402	None	0.61A	17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	3u7u	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	4 / 8	GLY A 311 GLY A 339 GLY A 375 ILE A 398	None	0.65A	17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	4a69	HISTONE DEACETYLASE 3, (Homo sapiens)	5 / 8	GLY A 257 GLY A 295 GLY A 132 HIS A 134 ILE A 150	None None None ACT  A 501 (-4.0A) None	1.01A	21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	4a69	HISTONE DEACETYLASE 3, (Homo sapiens)	5 / 8	GLY A 296 GLY A 295 GLY A 132 HIS A 134 ILE A 150	ACT  A 501 (-3.0A) None None ACT  A 501 (-4.0A) None	1.21A	21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	4bkx	HISTONE DEACETYLASE 1 (Homo sapiens)	5 / 8	GLY B 301 GLY B 300 GLY B 138 HIS B 140 ILE B 156	ACT  B 601 (-3.4A) ACT  B 601 ( 4.8A) None ACT  B 601 (-3.7A) None	1.26A	18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	4c2k	3-KETOACYL-COA THIOLASE, MITOCHONDRIAL (Homo sapiens)	4 / 8	GLY A 117 GLY A 118 GLY A 355 SER A  98	None	0.55A	28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	4c2k	3-KETOACYL-COA THIOLASE, MITOCHONDRIAL (Homo sapiens)	4 / 8	GLY A 117 GLY A 118 GLY A 356 SER A  98	None	0.70A	28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	4gwn	MEPRIN A SUBUNIT BETA (Homo sapiens)	5 / 8	GLY A 413 GLY A 414 ILE A 380 SER A 350 SER A 411	None	1.14A	20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	4iqy	O-ACETYL-ADP-RIBOSE DEACETYLASE MACROD2 (Homo sapiens)	4 / 8	GLY A  98 GLY A 103 HIS A 106 ILE A 105	AR6  A 301 ( 3.7A) None None None	0.68A	22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	5dot	CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL (Homo sapiens)	5 / 8	GLY A 510 GLY A 509 GLY A 429 ILE A 427 SER A 444	None	1.46A	12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	5jiu	RAN-BINDING PROTEIN 9 (Homo sapiens)	4 / 8	GLY A 246 GLY A 253 SER A 235 THR A 315	None	0.67A	22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	5o4g	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	4 / 8	GLY C 322 GLY C 350 GLY C 386 ILE C 409	None	0.57A	12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	5sx4	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	4 / 8	GLY M 315 GLY M 343 GLY M 379 ILE M 402	None	0.66A	21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IR0_A_FCNA202_1 (METALLOTHIOL TRANSFERASE FOSB 2)	2y1h	PUTATIVE DEOXYRIBONUCLEASE TATDN3 (Homo sapiens)	5 / 11	HIS A 170 ARG A 149 GLU A 107 HIS A  14 ALA A 221	ZN  A1273 (-3.2A) PO4  A1275 ( 4.9A) ZN  A1274 (-2.4A) ZN  A1274 ( 3.3A) PO4  A1275 ( 4.5A)	1.12A	19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JH4_B_FCNB202_1 (METALLOTHIOL TRANSFERASE FOSB)	2y1h	PUTATIVE DEOXYRIBONUCLEASE TATDN3 (Homo sapiens)	5 / 11	HIS A  14 ALA A 221 HIS A 170 ARG A 149 GLU A 107	ZN  A1274 ( 3.3A) PO4  A1275 ( 4.5A) ZN  A1273 (-3.2A) PO4  A1275 ( 4.9A) ZN  A1274 (-2.4A)	1.15A	18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V3D_A_FCNA205_1 (FOSFOMYCIN RESISTANCE PROTEIN)	5fzo	PROBABLE JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROT EIN 2C (Homo sapiens)	5 / 10	HIS A2466 THR A2333 TRP A2391 HIS A2336 GLU A2338	MN  A3499 (-3.4A) None None MN  A3499 (-3.4A) MN  A3499 (-2.5A)	1.21A	16.47