POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None None	0.34A	36.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-3.6A) None None	1.28A	36.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 901 ( 3.2A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A)	0.90A	36.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	2gy5	ANGIOPOIETIN-1 RECEPTOR (Homo sapiens)	5 / 10	VAL A 278 LEU A 129 THR A 130 THR A 128 PRO A 126	None	1.26A	20.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	7 / 10	HIS A  94 HIS A  96 HIS A 119 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None None	0.26A	60.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-3.6A) None None	1.27A	60.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 10	HIS A  96 PHE A  91 LEU A 198 THR A 199 TRP A 209	ZN  A 561 ( 3.2A) None PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	1.06A	60.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 PRO A 202	ZN  A 561 ( 3.2A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.90A	60.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	6 / 10	HIS A 118 HIS A 141 LEU A 222 THR A 223 PRO A 226 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None None	0.25A	39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	6 / 10	HIS A 118 HIS A 141 LEU A 222 THR A 223 PRO A 226 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None None	1.47A	39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	9 / 10	HIS A  95 HIS A  97 HIS A 120 VAL A 122 PHE A 132 LEU A 199 THR A 200 PRO A 203 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 (-4.6A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A) None	0.48A	60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	5 / 10	HIS A  95 HIS A  97 VAL A 144 LEU A 199 PRO A 203	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 ( 4.9A)	1.27A	60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	7 / 10	HIS A 111 HIS A 113 HIS A 138 VAL A 140 LEU A 219 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None	0.69A	34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	6 / 10	HIS A 138 VAL A 140 LEU A 219 THR A 220 PRO A 223 TRP A 230	MG  A 901 (-3.2A) None None None None None	0.72A	34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	5 / 10	LEU A 219 THR A 220 THR A 221 PRO A 223 TRP A 230	None	0.49A	34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	5 / 10	HIS A 129 LEU A 235 THR A 236 PRO A 239 TRP A 246	None	0.32A	30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	5 / 10	HIS A 129 PHE A 166 LEU A 235 THR A 236 PRO A 239	None	0.90A	30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	10 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 PHE A 131 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 (-4.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None None	0.24A	55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-3.4A) None None	1.28A	55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	7 / 10	HIS A  96 HIS A 119 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None None	1.47A	55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 263 ( 3.2A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	0.86A	55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 263 ( 3.1A) ZN  A 263 ( 3.2A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A)	1.39A	55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 PHE A 130 THR A 198 THR A 199 PRO A 201	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None None	0.49A	58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 PHE A 130 THR A 198 THR A 199 TRP A 208	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None None	0.35A	58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	5 / 10	HIS A  94 HIS A  96 VAL A 121 PHE A 130 THR A 199	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) None None None	1.31A	58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	10 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 PHE A 131 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None ZN  A 301 ( 4.4A) None None None	0.19A	95.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	6 / 10	HIS A  94 HIS A  96 VAL A 121 PHE A 131 LEU A 198 THR A 199	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) None None None ZN  A 301 ( 4.4A)	1.49A	95.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	7 / 10	HIS A  94 HIS A 119 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None ZN  A 301 ( 4.4A) None None None	1.39A	95.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	6 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 301 (-3.2A) None None ZN  A 301 ( 4.4A) None None	0.95A	95.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A) None None	0.39A	36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.1A) 520  A 302 (-3.4A) None None	1.29A	36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A)	0.90A	36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) ZN  A 301 ( 3.2A) EZL  A 302 (-4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) EZL  A 302 (-3.9A) None	0.23A	35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	6 / 10	HIS A  94 HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) EZL  A 302 (-3.9A)	1.08A	35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.2A) EZL  A 302 (-3.4A) None None	1.30A	35.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	6 / 10	HIS A  94 HIS A  96 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-3.2A) None None	1.18A	14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None None	0.39A	14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	6 / 10	HIS A  94 HIS A 119 LEU A 198 THR A 200 PRO A 202 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-3.6A) V14  A 302 (-3.5A) None None	1.49A	14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	6 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None	0.85A	14.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	10 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None None	0.30A	36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-3.6A) None None	1.29A	36.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2gy5	ANGIOPOIETIN-1 RECEPTOR (Homo sapiens)	5 / 10	VAL A 278 LEU A 129 THR A 130 THR A 128 PRO A 126	None	1.28A	20.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None None	0.33A	60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-3.6A) None None	1.29A	60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 PRO A 202	ZN  A 561 ( 3.2A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.97A	60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	6 / 10	HIS A 118 HIS A 141 LEU A 222 THR A 223 PRO A 226 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None None	0.27A	39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	6 / 10	HIS A 118 HIS A 141 LEU A 222 THR A 223 PRO A 226 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None None	1.48A	39.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2xmr	PROTEIN NDRG2 (Homo sapiens)	5 / 10	VAL A 129 VAL A 153 LEU A 289 THR A 290 PRO A 286	None	1.03A	21.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	9 / 10	HIS A  95 HIS A  97 HIS A 120 VAL A 122 VAL A 144 LEU A 199 THR A 200 PRO A 203 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A) None	0.41A	60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	5 / 10	HIS A  95 HIS A  97 VAL A 144 LEU A 199 PRO A 203	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 ( 4.9A)	1.30A	60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	5 / 10	HIS A  97 VAL A 122 LEU A 199 THR A 200 PRO A 203	ZN  A 301 ( 3.5A) 4MD  A 401 ( 4.6A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A)	0.93A	60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	8 / 10	HIS A 111 HIS A 113 HIS A 138 VAL A 140 VAL A 161 LEU A 219 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None	0.62A	35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	5 / 10	HIS A 113 HIS A 138 HIS A 111 THR A 220 PRO A 222	MG  A 901 (-3.4A) MG  A 901 (-3.2A) MG  A 901 (-3.4A) None None	1.20A	35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	8 / 10	HIS A 113 HIS A 138 VAL A 140 VAL A 161 LEU A 219 THR A 220 PRO A 223 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None None	0.73A	35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	5 / 10	LEU A 219 THR A 220 THR A 221 PRO A 223 TRP A 230	None	0.49A	35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	5 / 10	HIS A 129 LEU A 235 THR A 236 PRO A 239 TRP A 246	None	0.25A	30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	10 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None None	0.24A	56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	7 / 10	HIS A  94 HIS A 119 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None None	1.48A	56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 10	HIS A  94 HIS A 119 VAL A 143 THR A 199 PRO A 201 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) None None	1.28A	56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 10	HIS A  96 VAL A 121 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	1.01A	56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 200 PRO A 202	ZN  A 263 ( 3.1A) ZN  A 263 ( 3.2A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	1.42A	56.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 THR A 199 PRO A 201	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None None	0.50A	58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 THR A 199 TRP A 208	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None None	0.36A	58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	10 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None ZN  A 301 ( 4.4A) None None None	0.17A	95.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	7 / 10	HIS A  94 HIS A 119 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None ZN  A 301 ( 4.4A) None None None	1.41A	95.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	6 / 10	HIS A  96 VAL A 121 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 301 (-3.2A) None None ZN  A 301 ( 4.4A) None None	0.91A	95.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	10 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A) None None	0.33A	36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	6 / 10	HIS A  94 HIS A 119 LEU A 198 THR A 199 PRO A 201 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.1A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) None None	1.44A	36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  96 VAL A 121 LEU A 198 THR A 200 PRO A 202	ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) GOL  A 303 ( 3.5A) None	0.81A	36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A)	0.96A	36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) ZN  A 301 ( 3.2A) EZL  A 302 (-4.7A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) EZL  A 302 (-3.9A) None	0.23A	35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	5 / 10	HIS A  94 HIS A  96 VAL A 143 LEU A 198 THR A 200	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.9A)	1.14A	35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.2A) EZL  A 302 (-3.4A) None None	1.31A	35.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	10 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None None	0.36A	14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DCW_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-3.2A) None None	1.23A	14.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	10 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None None	0.32A	36.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	6 / 10	HIS A  96 HIS A 119 LEU A 198 THR A 199 THR A 200 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None	1.49A	36.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	6 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 901 ( 3.1A) ZN  A 901 ( 3.2A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A)	1.44A	36.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2gy5	ANGIOPOIETIN-1 RECEPTOR (Homo sapiens)	5 / 10	VAL A 278 LEU A 129 THR A 130 THR A 128 PRO A 126	None	1.27A	20.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None None	0.34A	60.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 PRO A 202	ZN  A 561 ( 3.2A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.95A	60.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	6 / 10	HIS A 118 HIS A 141 LEU A 222 THR A 223 PRO A 226 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None None	0.28A	39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	6 / 10	HIS A 118 HIS A 141 LEU A 222 THR A 223 PRO A 226 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None None	1.44A	39.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	2xmr	PROTEIN NDRG2 (Homo sapiens)	5 / 10	VAL A 129 VAL A 153 LEU A 289 THR A 290 PRO A 286	None	1.05A	21.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	9 / 10	HIS A  95 HIS A  97 HIS A 120 VAL A 122 VAL A 144 LEU A 199 THR A 200 PRO A 203 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A) None	0.44A	60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	5 / 10	HIS A  95 HIS A  97 VAL A 144 LEU A 199 PRO A 203	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 ( 4.9A)	1.29A	60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	5 / 10	HIS A  97 VAL A 122 LEU A 199 THR A 200 PRO A 203	ZN  A 301 ( 3.5A) 4MD  A 401 ( 4.6A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A)	0.93A	60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	8 / 10	HIS A 111 HIS A 113 HIS A 138 VAL A 140 VAL A 161 LEU A 219 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None	0.63A	34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	5 / 10	HIS A 111 HIS A 113 VAL A 161 LEU A 219 THR A 220	MG  A 901 (-3.4A) MG  A 901 (-3.4A) None None None	1.25A	34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	5 / 10	HIS A 113 HIS A 138 HIS A 111 THR A 220 PRO A 222	MG  A 901 (-3.4A) MG  A 901 (-3.2A) MG  A 901 (-3.4A) None None	1.19A	34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	8 / 10	HIS A 113 HIS A 138 VAL A 140 VAL A 161 LEU A 219 THR A 220 PRO A 223 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None None	0.73A	34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	5 / 10	LEU A 219 THR A 220 THR A 221 PRO A 223 TRP A 230	None	0.47A	34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	5 / 10	HIS A 129 LEU A 235 THR A 236 PRO A 239 TRP A 246	None	0.28A	30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	10 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None None	0.24A	55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 10	HIS A  96 VAL A 121 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	1.00A	55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 200 PRO A 202	ZN  A 263 ( 3.1A) ZN  A 263 ( 3.2A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	1.41A	55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 THR A 199 PRO A 201	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None None	0.53A	58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 THR A 199 TRP A 208	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None None	0.36A	58.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	10 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None ZN  A 301 ( 4.4A) None None None	0.17A	95.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	7 / 10	HIS A  94 HIS A 119 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None ZN  A 301 ( 4.4A) None None None	1.44A	95.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 10	HIS A  94 VAL A 207 THR A 199 THR A 200 TRP A 209	ZN  A 301 (-3.2A) None ZN  A 301 ( 4.4A) None None	1.27A	95.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	6 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 200 PRO A 202	ZN  A 301 (-3.1A) ZN  A 301 (-3.2A) None None None None	1.45A	95.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	10 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A) None None	0.35A	36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  96 VAL A 121 LEU A 198 THR A 200 PRO A 202	ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) GOL  A 303 ( 3.5A) None	0.83A	36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A)	0.95A	36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) ZN  A 301 ( 3.2A) EZL  A 302 (-4.7A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) EZL  A 302 (-3.9A) None	0.24A	35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	5 / 10	HIS A  94 HIS A  96 VAL A 143 LEU A 198 THR A 200	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.9A)	1.13A	35.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	5zqz	TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL (Homo sapiens)	5 / 10	HIS A 498 VAL A 591 LEU A 551 THR A 548 THR A 547	None	1.10A	17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	10 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None None	0.36A	14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	7 / 10	HIS A  94 HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None	1.00A	14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-3.2A) None None	1.25A	14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DD0_A_EZLA301_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	7 / 10	HIS A  96 HIS A 119 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None None	1.48A	14.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	10 / 11	HIS A  94 HIS A  96 GLU A 106 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 4.5A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None None	0.33A	37.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 11	HIS A  94 HIS A  96 HIS A 119 VAL A 121 ALA A 131	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) None	1.13A	37.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	7 / 11	HIS A  96 GLU A 106 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 901 ( 3.2A) ZN  A 901 ( 4.5A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None	1.06A	37.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	7 / 11	HIS A  96 HIS A 119 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None None	1.47A	37.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	1zy8	DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL (Homo sapiens)	5 / 11	GLU A 431 HIS A 450 ALA A 394 LEU A 455 PRO A 423	None	1.18A	17.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	9 / 11	HIS A  94 HIS A  96 GLU A 106 HIS A 119 ALA A 135 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 4.9A) ZN  A 561 ( 3.1A) None PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None None	0.58A	51.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	6 / 11	HIS A  96 GLU A 106 VAL A 143 LEU A 198 THR A 199 PRO A 202	ZN  A 561 ( 3.2A) ZN  A 561 ( 4.9A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.88A	51.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	7 / 11	HIS A 118 GLU A 128 HIS A 141 LEU A 222 THR A 223 PRO A 226 TRP A 233	CL  A 401 (-4.2A) None CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None None	0.28A	40.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	6 / 11	HIS A 118 HIS A 141 LEU A 222 THR A 223 PRO A 226 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None None	1.47A	40.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	10 / 11	HIS A  95 HIS A  97 GLU A 107 HIS A 120 VAL A 122 ALA A 136 LEU A 199 THR A 200 PRO A 203 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 4.9A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 (-3.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A) None	0.56A	51.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	5 / 11	HIS A  97 GLU A 107 VAL A 144 LEU A 199 PRO A 203	ZN  A 301 ( 3.5A) ZN  A 301 ( 4.9A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 ( 4.9A)	1.00A	51.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	5 / 11	GLU A 125 HIS A 113 THR A 220 THR A 221 PRO A 223	MG  A 901 ( 4.4A) MG  A 901 (-3.4A) None None None	1.23A	35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	6 / 11	GLU A 125 LEU A 219 THR A 220 THR A 221 PRO A 223 TRP A 230	MG  A 901 ( 4.4A) None None None None None	0.64A	35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	8 / 11	HIS A 111 HIS A 113 GLU A 125 HIS A 138 VAL A 140 LEU A 219 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 ( 4.4A) MG  A 901 (-3.2A) None None None None	0.69A	35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	8 / 11	HIS A 113 GLU A 125 HIS A 138 VAL A 140 LEU A 219 THR A 220 PRO A 223 TRP A 230	MG  A 901 (-3.4A) MG  A 901 ( 4.4A) MG  A 901 (-3.2A) None None None None None	0.72A	35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	5 / 11	HIS A 113 HIS A 138 HIS A 111 THR A 220 PRO A 222	MG  A 901 (-3.4A) MG  A 901 (-3.2A) MG  A 901 (-3.4A) None None	1.15A	35.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	6 / 11	HIS A 129 GLU A 141 LEU A 235 THR A 236 PRO A 239 TRP A 246	None	0.32A	29.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	5 / 11	HIS A 129 LEU A 235 THR A 236 PRO A 239 TRP A 246	None	1.24A	29.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	11 / 11	HIS A  94 HIS A  96 GLU A 106 HIS A 119 VAL A 121 ALA A 135 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 4.6A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) None AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None None	0.54A	95.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	7 / 11	HIS A  96 GLU A 106 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 263 ( 3.2A) ZN  A 263 ( 4.6A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	0.88A	95.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	7 / 11	HIS A  96 HIS A 119 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None None	1.46A	95.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 11	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 263 ( 3.1A) ZN  A 263 ( 3.2A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A)	1.39A	95.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	8 / 11	HIS A  94 HIS A  96 GLU A 106 HIS A 119 VAL A 121 THR A 198 THR A 199 PRO A 201	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 ( 4.9A) ZN  A 261 (-3.2A) None ZN  A 261 ( 4.4A) None None	0.47A	47.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	8 / 11	HIS A  94 HIS A  96 GLU A 106 HIS A 119 VAL A 121 THR A 198 THR A 199 TRP A 208	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 ( 4.9A) ZN  A 261 (-3.2A) None ZN  A 261 ( 4.4A) None None	0.36A	47.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	5 / 11	HIS A  96 GLU A 106 VAL A 142 THR A 198 THR A 199	ZN  A 261 (-3.3A) ZN  A 261 ( 4.9A) None ZN  A 261 ( 4.4A) None	0.67A	47.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	4cns	DIHYDROPYRIMIDINASE- LIKE 3 (Homo sapiens)	5 / 11	HIS A  75 HIS A  73 HIS A 107 ALA A 169 THR A 253	None None None CL  A1493 ( 3.7A) None	1.24A	18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	4cnt	DIHYDROPYRIMIDINASE- LIKE 3 (Homo sapiens)	5 / 11	HIS A  75 HIS A  73 HIS A 107 ALA A 169 THR A 253	None	1.25A	17.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	10 / 11	HIS A  94 HIS A  96 GLU A 106 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 ( 4.5A) ZN  A 301 (-3.1A) None None ZN  A 301 ( 4.4A) None None None	0.23A	51.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	7 / 11	HIS A  96 GLU A 106 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 301 (-3.2A) ZN  A 301 ( 4.5A) None None ZN  A 301 ( 4.4A) None None	0.92A	51.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	6 / 11	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 (-3.1A) ZN  A 301 (-3.2A) None None ZN  A 301 ( 4.4A) None	1.36A	51.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	11 / 11	HIS A  94 HIS A  96 GLU A 106 HIS A 119 VAL A 121 ALA A 135 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 4.6A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 ( 3.7A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A) None None	0.38A	35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	6 / 11	HIS A  96 GLU A 106 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) ZN  A 301 ( 4.6A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A)	0.92A	35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	9 / 11	HIS A  94 HIS A  96 GLU A 106 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) ZN  A 301 ( 4.6A) ZN  A 301 ( 3.2A) EZL  A 302 (-4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) EZL  A 302 (-3.9A) None	0.26A	32.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	6 / 11	HIS A  96 GLU A 106 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.3A) ZN  A 301 ( 4.6A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) EZL  A 302 (-3.9A)	0.91A	32.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	10 / 11	HIS A  94 HIS A  96 GLU A 106 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) V14  A 302 (-4.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None None	0.33A	23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 11	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-3.2A) None None	1.26A	23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDZ_A_EZLA264_1 (CARBONIC ANHYDRASE 7)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	7 / 11	HIS A  96 GLU A 106 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 301 ( 3.2A) V14  A 302 (-4.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None	0.88A	23.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM  A1400 (-3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None	0.41A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	6 / 10	GLN A  92 HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	AZM  A1400 (-3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.3A)	1.44A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 10	HIS A  96 HIS A  94 THR A 200 THR A 199 TRP A   5	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-3.3A) AZM  A1400 (-3.6A) None	1.40A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 901 ( 3.2A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A)	1.08A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	8 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199 TRP A 209	None ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.61A	31.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	5 / 10	HIS A 118 HIS A 141 LEU A 222 THR A 223 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None	0.21A	31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	8 / 10	HIS A  95 HIS A  97 HIS A 120 VAL A 122 VAL A 144 LEU A 199 THR A 200 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) None	0.42A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	9 / 10	GLN A 109 HIS A 111 HIS A 113 HIS A 138 VAL A 140 VAL A 161 LEU A 219 THR A 220 TRP A 230	None MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None	0.68A	32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	GLN A  67 HIS A  96 VAL A 121 THR A 199 THR A 200	None ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A)	1.12A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM  A 264 (-4.1A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	0.26A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	HIS A  96 HIS A  94 THR A 200 THR A 199 TRP A   5	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) AZM  A 264 (-3.5A) AZM  A 264 (-3.4A) None	1.42A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	HIS A  96 HIS A  94 VAL A 121 LEU A 198 THR A 199	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A)	1.38A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	HIS A  96 VAL A 121 LEU A 198 THR A 199 THR A 200	ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A)	0.92A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 200	ZN  A 263 ( 3.1A) ZN  A 263 ( 3.2A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A)	1.48A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	9 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 THR A 199 TRP A 208	None ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None None	0.29A	34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	5 / 10	GLN A  92 HIS A  94 HIS A  96 VAL A 121 THR A 199	None ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) None None	1.15A	34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	5 / 10	HIS A 119 HIS A  96 VAL A 142 THR A 198 THR A 199	ZN  A 261 (-3.2A) ZN  A 261 (-3.3A) None ZN  A 261 ( 4.4A) None	1.44A	34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	None ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None ZN  A 301 ( 4.4A) None None	0.28A	35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 10	HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) None None None	1.14A	35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 (-3.2A) None None ZN  A 301 ( 4.4A) None	1.05A	35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 200	ZN  A 301 (-3.1A) ZN  A 301 (-3.2A) None None None	1.47A	35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	GOL  A 303 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A) None	0.37A	35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  94 VAL A 207 THR A 199 THR A 200 TRP A 209	ZN  A 301 (-3.2A) None 520  A 302 (-3.4A) GOL  A 303 ( 3.5A) None	1.33A	35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A)	1.09A	35.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	V14  A 302 (-3.8A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None	0.36A	16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A)	0.96A	16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_A_EZLA302_1 (CARBONIC ANHYDRASE 4)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199	ZN  A 301 ( 3.1A) ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A)	1.42A	16.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM  A1400 (-3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None	0.33A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	6 / 10	GLN A  92 HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	AZM  A1400 (-3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.3A)	1.43A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	6 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 901 ( 3.1A) ZN  A 901 ( 3.2A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A)	1.45A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	8 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199 TRP A 209	None ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.55A	31.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	5 / 10	HIS A 118 HIS A 141 LEU A 222 THR A 223 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None	0.19A	31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	5 / 10	GLN A  93 HIS A  95 HIS A  97 LEU A 199 THR A 200	4MD  A 401 (-3.1A) ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A)	0.86A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	8 / 10	HIS A  95 HIS A  97 HIS A 120 VAL A 122 VAL A 144 LEU A 199 THR A 200 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) None	0.42A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	9 / 10	GLN A 109 HIS A 111 HIS A 113 HIS A 138 VAL A 140 VAL A 161 LEU A 219 THR A 220 TRP A 230	None MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None	0.68A	32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	5 / 10	HIS A 138 LEU A 219 THR A 220 THR A 221 TRP A 230	MG  A 901 (-3.2A) None None None None	0.70A	32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	GLN A  67 HIS A  94 HIS A  96 THR A 199 THR A 200	None ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A)	1.07A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	GLN A  67 HIS A  96 VAL A 121 THR A 199 THR A 200	None ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A)	1.10A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM  A 264 (-4.1A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	0.30A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	HIS A  96 HIS A  94 VAL A 121 LEU A 198 THR A 199	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A)	1.42A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 200	ZN  A 263 ( 3.1A) ZN  A 263 ( 3.2A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A)	1.42A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	9 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 THR A 199 TRP A 208	None ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None None	0.37A	34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	5 / 10	GLN A  92 HIS A  94 HIS A  96 VAL A 121 THR A 198	None ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) None ZN  A 261 ( 4.4A)	1.29A	34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	5 / 10	HIS A 119 HIS A  96 VAL A 142 THR A 198 THR A 199	ZN  A 261 (-3.2A) ZN  A 261 (-3.3A) None ZN  A 261 ( 4.4A) None	1.40A	34.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	4n40	PROTEIN ECT2 (Homo sapiens)	5 / 10	HIS A 279 VAL A 281 VAL A 301 THR A 262 TRP A 305	None	1.31A	22.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	None ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None ZN  A 301 ( 4.4A) None None	0.31A	35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 10	HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) None None None	1.16A	35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 (-3.2A) None None ZN  A 301 ( 4.4A) None	0.95A	35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 200	ZN  A 301 (-3.1A) ZN  A 301 (-3.2A) None None None	1.41A	35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	6 / 10	GLN A  67 HIS A  94 HIS A  96 HIS A 119 THR A 199 THR A 200	GOL  A 303 (-3.4A) ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A)	1.03A	35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	GOL  A 303 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A) None	0.36A	35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  94 VAL A 207 THR A 199 THR A 200 TRP A 209	ZN  A 301 (-3.2A) None 520  A 302 (-3.4A) GOL  A 303 ( 3.5A) None	1.36A	35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A)	0.98A	35.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	V14  A 302 (-3.8A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None	0.34A	16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A)	0.84A	16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_B_EZLB302_1 (CARBONIC ANHYDRASE 4)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199	ZN  A 301 ( 3.1A) ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A)	1.38A	16.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	9 / 9	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM  A1400 (-3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None	0.40A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	6 / 9	GLN A  92 HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	AZM  A1400 (-3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.3A)	1.42A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 9	HIS A  96 HIS A  94 THR A 200 THR A 199 TRP A   5	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-3.3A) AZM  A1400 (-3.6A) None	1.38A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	6 / 9	HIS A  96 HIS A 119 LEU A 198 THR A 199 THR A 200 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None	1.50A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 9	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 901 ( 3.2A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A)	1.03A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 9	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199	ZN  A 901 ( 3.1A) ZN  A 901 ( 3.2A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A)	1.45A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	7 / 9	GLN A  92 HIS A  94 HIS A  96 HIS A 119 LEU A 198 THR A 199 TRP A 209	None ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.58A	31.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 9	HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A)	1.14A	31.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	5 / 9	HIS A 118 HIS A 141 LEU A 222 THR A 223 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None	0.21A	31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	7 / 9	HIS A  95 HIS A  97 HIS A 120 VAL A 122 LEU A 199 THR A 200 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) None	0.46A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	8 / 9	GLN A 109 HIS A 111 HIS A 113 HIS A 138 VAL A 140 LEU A 219 THR A 220 TRP A 230	None MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None	0.68A	32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	9 / 9	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM  A 264 (-4.1A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	0.21A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 9	HIS A  96 HIS A  94 THR A 200 THR A 199 TRP A   5	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) AZM  A 264 (-3.5A) AZM  A 264 (-3.4A) None	1.39A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 9	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 263 ( 3.2A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A)	0.99A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 9	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199	ZN  A 263 ( 3.1A) ZN  A 263 ( 3.2A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A)	1.45A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	8 / 9	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 THR A 198 THR A 199 TRP A 208	None ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None ZN  A 261 ( 4.4A) None None	0.29A	34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	5 / 9	GLN A  92 HIS A  94 HIS A  96 VAL A 121 THR A 199	None ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) None None	1.12A	34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	9 / 9	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 TRP A 209	None ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None ZN  A 301 ( 4.4A) None None	0.23A	35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 9	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 (-3.2A) None None ZN  A 301 ( 4.4A) None	0.99A	35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	9 / 9	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 TRP A 209	GOL  A 303 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A) None	0.33A	35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	6 / 9	GLN A  92 HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	GOL  A 303 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) GOL  A 303 ( 3.5A)	1.37A	35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 9	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A)	1.02A	35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 9	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199	ZN  A 301 ( 3.1A) ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A)	1.47A	35.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	9 / 9	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 THR A 200 TRP A 209	V14  A 302 (-3.8A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None	0.37A	16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 9	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A)	0.92A	16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_C_EZLC302_1 (CARBONIC ANHYDRASE 4)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 9	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199	ZN  A 301 ( 3.1A) ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A)	1.38A	16.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM  A1400 (-3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None	0.42A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	6 / 10	GLN A  92 HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	AZM  A1400 (-3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.3A)	1.46A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 10	HIS A  94 VAL A 207 THR A 199 THR A 200 TRP A 209	ZN  A 901 ( 3.2A) None AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None	1.30A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 10	HIS A  96 HIS A  94 THR A 200 THR A 199 TRP A   5	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-3.3A) AZM  A1400 (-3.6A) None	1.35A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 901 ( 3.2A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A)	1.05A	35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	8 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199 TRP A 209	None ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.62A	31.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 10	HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A)	1.15A	31.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	5 / 10	HIS A 118 HIS A 141 LEU A 222 THR A 223 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None	0.20A	31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	5 / 10	GLN A  93 HIS A  95 HIS A  97 LEU A 199 THR A 200	4MD  A 401 (-3.1A) ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A)	0.94A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	8 / 10	HIS A  95 HIS A  97 HIS A 120 VAL A 122 VAL A 144 LEU A 199 THR A 200 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) None	0.44A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	9 / 10	GLN A 109 HIS A 111 HIS A 113 HIS A 138 VAL A 140 VAL A 161 LEU A 219 THR A 220 TRP A 230	None MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None	0.63A	32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	GLN A  67 HIS A  96 VAL A 121 THR A 199 THR A 200	None ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A)	1.12A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM  A 264 (-4.1A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	0.25A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	HIS A  96 HIS A  94 THR A 200 THR A 199 TRP A   5	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) AZM  A 264 (-3.5A) AZM  A 264 (-3.4A) None	1.37A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	HIS A  96 HIS A  94 VAL A 121 LEU A 198 THR A 199	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A)	1.35A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	HIS A  96 VAL A 121 LEU A 198 THR A 199 THR A 200	ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A)	0.91A	34.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	9 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 THR A 199 TRP A 208	None ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None None	0.30A	34.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	5 / 10	GLN A  92 HIS A  94 HIS A  96 VAL A 121 THR A 198	None ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) None ZN  A 261 ( 4.4A)	1.23A	34.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	4n40	PROTEIN ECT2 (Homo sapiens)	5 / 10	HIS A 279 VAL A 281 VAL A 301 THR A 262 TRP A 305	None	1.32A	22.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	None ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None ZN  A 301 ( 4.4A) None None	0.26A	35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 10	HIS A  96 HIS A  94 VAL A 121 LEU A 198 THR A 199	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) None None ZN  A 301 ( 4.4A)	1.32A	35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	GOL  A 303 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A) None	0.34A	35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  94 VAL A 207 THR A 199 THR A 200 TRP A 209	ZN  A 301 (-3.2A) None 520  A 302 (-3.4A) GOL  A 303 ( 3.5A) None	1.32A	35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A)	1.05A	35.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	5zqz	TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL (Homo sapiens)	5 / 10	HIS A 498 VAL A 591 LEU A 551 THR A 548 THR A 547	None	1.11A	15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	10 / 10	GLN A  92 HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	V14  A 302 (-3.8A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None	0.34A	16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A)	0.92A	16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JN9_D_EZLD302_1 (CARBONIC ANHYDRASE 4)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 10	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199	ZN  A 301 ( 3.1A) ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A)	1.43A	16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) None None	0.46A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 10	HIS A  94 HIS A  96 VAL A 121 LEU A 198 PRO A 202	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) None	1.03A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-3.6A) None None	1.32A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None None	0.43A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	6 / 10	HIS A  94 HIS A 119 VAL A 143 LEU A 198 PRO A 202 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) None None	1.46A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 PRO A 202	ZN  A 561 ( 3.2A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	1.04A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	6 / 10	HIS A 118 HIS A 141 LEU A 222 THR A 223 PRO A 226 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None None	0.29A	27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	9 / 10	HIS A  95 HIS A  97 HIS A 120 VAL A 122 VAL A 144 LEU A 199 THR A 200 PRO A 203 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A) None	0.42A	28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	5 / 10	HIS A  97 VAL A 122 LEU A 199 THR A 200 PRO A 203	ZN  A 301 ( 3.5A) 4MD  A 401 ( 4.6A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A)	0.86A	28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	8 / 10	HIS A 111 HIS A 113 HIS A 138 VAL A 140 VAL A 161 LEU A 219 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None	0.72A	28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	7 / 10	HIS A 138 VAL A 140 VAL A 161 LEU A 219 THR A 220 PRO A 223 TRP A 230	MG  A 901 (-3.2A) None None None None None None	0.81A	28.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	5 / 10	HIS A 129 LEU A 235 THR A 236 PRO A 239 TRP A 246	None	0.41A	30.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) None None	0.32A	28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 10	HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 199 PRO A 202	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) None	1.11A	28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-3.4A) None None	1.33A	28.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	6 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 THR A 198 PRO A 201	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None ZN  A 261 ( 4.4A) None	0.49A	30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	7 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 TRP A 208	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None	0.42A	30.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	4kt1	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4 R-SPONDIN-1 (Homo sapiens)	5 / 10	HIS A 157 VAL A 109 ALA E 104 PRO E  81 TRP A 159	None	1.13A	18.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None ZN  A 301 ( 4.4A) None None	0.36A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 10	HIS A  94 HIS A  96 VAL A 121 LEU A 198 PRO A 202	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) None None None	1.02A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 PRO A 202	ZN  A 301 (-3.2A) None None ZN  A 301 ( 4.4A) None	1.16A	30.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) None None	0.52A	28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 10	HIS A  94 HIS A  96 VAL A 121 LEU A 198 PRO A 202	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) None	1.10A	28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) ZN  A 301 ( 3.2A) EZL  A 302 (-4.7A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) None	0.31A	28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	6 / 10	HIS A  94 HIS A  96 HIS A 119 THR A 199 PRO A 201 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-3.2A) None None	1.22A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) None None	0.44A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 10	HIS A  94 HIS A  96 VAL A 121 LEU A 198 PRO A 202	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) V14  A 302 (-4.7A) V14  A 302 (-3.6A) None	1.16A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_A_EZLA303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 PRO A 202	ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) None	1.02A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) None	0.36A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 9	HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.3A)	1.49A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	2i99	MU-CRYSTALLIN HOMOLOG (Homo sapiens)	5 / 9	VAL A 297 VAL A 301 LEU A  31 THR A  29 ALA A  32	None	1.27A	18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	7 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.36A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	5 / 9	HIS A 118 HIS A 141 LEU A 222 THR A 223 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None	0.42A	27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	8 / 9	HIS A  95 HIS A  97 HIS A 120 VAL A 122 VAL A 144 LEU A 199 THR A 200 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) None	0.40A	28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	8 / 9	HIS A 111 HIS A 113 HIS A 138 VAL A 140 VAL A 161 LEU A 219 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None	0.78A	28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) None	0.31A	28.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	7 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 TRP A 208	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None	0.48A	30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None ZN  A 301 ( 4.4A) None	0.33A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 9	HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 199	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) None None ZN  A 301 ( 4.4A)	1.15A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 9	HIS A  96 HIS A  94 VAL A 121 LEU A 198 THR A 199	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) None None ZN  A 301 ( 4.4A)	1.22A	30.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) None	0.37A	28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) ZN  A 301 ( 3.2A) EZL  A 302 (-4.7A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) None	0.39A	28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) None	0.41A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) None None	0.40A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	6 / 10	HIS A  94 HIS A 119 LEU A 198 THR A 199 PRO A 201 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) None None	1.50A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None None	0.41A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 10	HIS A  96 VAL A 143 LEU A 198 THR A 199 PRO A 202	ZN  A 561 ( 3.2A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	1.05A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	6 / 10	HIS A 118 HIS A 141 LEU A 222 THR A 223 PRO A 226 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None None	0.34A	27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	9 / 10	HIS A  95 HIS A  97 HIS A 120 VAL A 122 VAL A 144 LEU A 199 THR A 200 PRO A 203 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A) None	0.46A	28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	5 / 10	HIS A  97 VAL A 122 LEU A 199 THR A 200 PRO A 203	ZN  A 301 ( 3.5A) 4MD  A 401 ( 4.6A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A)	0.83A	28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	7 / 10	HIS A 111 HIS A 113 HIS A 138 VAL A 140 LEU A 219 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None	0.72A	28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	7 / 10	HIS A 111 HIS A 113 HIS A 138 VAL A 140 VAL A 161 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None	0.57A	28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	7 / 10	HIS A 113 HIS A 138 VAL A 140 LEU A 219 THR A 220 PRO A 223 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None	0.77A	28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	7 / 10	HIS A 113 HIS A 138 VAL A 140 VAL A 161 THR A 220 PRO A 223 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None	0.71A	28.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	5 / 10	HIS A 129 LEU A 235 THR A 236 PRO A 239 TRP A 246	None	0.38A	30.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) None None	0.32A	28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 10	HIS A  96 VAL A 121 LEU A 198 THR A 199 PRO A 202	ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) None	0.95A	28.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	7 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 PRO A 201	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None	0.58A	30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	7 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 TRP A 208	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None	0.36A	30.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	4ay1	CHITINASE-3-LIKE PROTEIN 2 (Homo sapiens)	5 / 10	VAL A 328 LEU A 275 THR A 274 ALA A 286 PRO A 285	None	1.33A	21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	4kt1	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4 R-SPONDIN-1 (Homo sapiens)	5 / 10	HIS A 157 VAL A 109 ALA E 104 PRO E  81 TRP A 159	None	1.20A	18.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	7 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 PRO A 202	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None ZN  A 301 ( 4.4A) None	1.00A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None ZN  A 301 ( 4.4A) None None	0.33A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	6 / 10	HIS A  94 HIS A 119 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None ZN  A 301 ( 4.4A) None None	1.38A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 10	HIS A  96 HIS A  94 VAL A 121 LEU A 198 THR A 199	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) None None ZN  A 301 ( 4.4A)	1.34A	30.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) None None	0.47A	28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	6 / 10	HIS A  96 HIS A  94 VAL A 121 LEU A 198 THR A 199 PRO A 202	ZN  A 301 ( 3.2A) ZN  A 301 (-3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) None	1.45A	28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	8 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) ZN  A 301 ( 3.2A) EZL  A 302 (-4.7A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) None	0.35A	28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	7 / 10	HIS A  94 HIS A  96 HIS A 119 LEU A 198 THR A 199 PRO A 201 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-3.6A) V14  A 302 (-3.2A) None None	1.37A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	9 / 10	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) None None	0.40A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_C_EZLC303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 10	HIS A  94 HIS A 119 LEU A 198 PRO A 202 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-3.6A) None None	1.34A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) None	0.33A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	7 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.36A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 9	HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A)	1.04A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	5 / 9	HIS A 118 HIS A 141 LEU A 222 THR A 223 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None	0.29A	27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	2z5d	UBIQUITIN-CONJUGATIN G ENZYME E2 H (Homo sapiens)	5 / 9	HIS A  42 VAL A  44 VAL A  55 LEU A 120 THR A 121	None	1.34A	20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	8 / 9	HIS A  95 HIS A  97 HIS A 120 VAL A 122 VAL A 144 LEU A 199 THR A 200 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) None	0.52A	28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	8 / 9	HIS A 111 HIS A 113 HIS A 138 VAL A 140 VAL A 161 LEU A 219 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None	0.70A	28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) None	0.33A	28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 9	HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A)	1.05A	28.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	7 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 TRP A 208	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None	0.53A	30.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	4px9	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	5 / 9	VAL A 345 VAL A 271 LEU A 235 THR A 231 ALA A 232	None None None ADP  A 601 (-4.1A) None	1.44A	22.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None ZN  A 301 ( 4.4A) None	0.35A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 9	HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199	ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None ZN  A 301 ( 4.4A)	1.04A	30.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) None	0.36A	28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 9	HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A)	1.03A	28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	5deu	METHYLCYTOSINE DIOXYGENASE TET2, CHIMERIC CONSTRUCT (Homo sapiens)	5 / 9	HIS A1416 HIS A1881 VAL A1395 VAL A1900 ALA A1379	OGA  A2001 (-3.9A) FE  A2003 ( 3.2A) OGA  A2001 ( 4.9A) OGA  A2001 ( 4.9A) OGA  A2001 ( 4.4A)	1.42A	18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	5e7j	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	5 / 9	VAL A 345 VAL A 271 LEU A 235 THR A 231 ALA A 232	None None None AMP  A 801 (-3.5A) AMP  A 801 ( 4.3A)	1.42A	18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) ZN  A 301 ( 3.2A) EZL  A 302 (-4.7A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) None	0.42A	28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	5 / 9	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.3A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A)	1.47A	28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) None	0.47A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 9	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199	ZN  A 301 ( 3.1A) ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A)	1.42A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	8 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) None	0.44A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 8	HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.3A)	1.44A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	7 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.50A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 8	HIS A  94 HIS A 119 VAL A 143 LEU A 198 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) None	1.43A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	5 / 8	HIS A 118 HIS A 141 LEU A 222 THR A 223 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None	0.43A	27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	8 / 8	HIS A  95 HIS A  97 HIS A 120 VAL A 122 VAL A 144 LEU A 199 THR A 200 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) None	0.48A	28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	3fc8	TRANSTHYRETIN (Homo sapiens)	4 / 8	VAL A  71 VAL A  32 LEU A  58 THR A  59	None	0.85A	19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	7 / 8	HIS A 111 HIS A 113 HIS A 138 VAL A 140 LEU A 219 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None	0.81A	28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	7 / 8	HIS A 111 HIS A 113 HIS A 138 VAL A 140 VAL A 161 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None	0.71A	28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	3gbj	KIF13B PROTEIN (Homo sapiens)	4 / 8	HIS A 223 VAL A 225 VAL A 252 LEU A 314	UNX  A   1 ( 4.6A) None None None	0.84A	21.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	4 / 8	HIS A 129 LEU A 235 THR A 236 TRP A 246	None	0.49A	30.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	8 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) None	0.38A	28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 8	HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A)	1.48A	28.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	7 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 TRP A 208	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None	0.47A	30.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	4a14	KINESIN-LIKE PROTEIN KIF7 (Homo sapiens)	4 / 8	HIS A 215 VAL A 217 VAL A 248 LEU A 307	None	0.85A	20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	4b4o	EPIMERASE FAMILY PROTEIN SDR39U1 (Homo sapiens)	4 / 8	HIS A  25 VAL A  27 VAL A   3 THR A 203	None	0.78A	20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	4bn2	KINESIN-LIKE PROTEIN KIF15 (Homo sapiens)	4 / 8	HIS A 223 VAL A 225 VAL A 250 LEU A 310	None	0.81A	19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	4kkd	MANNAN-BINDING LECTIN SERINE PROTEASE 1 (Homo sapiens)	4 / 8	VAL A 516 VAL A 469 LEU A 499 TRP A 480	None	0.76A	18.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None	1.08A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	8 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None ZN  A 301 ( 4.4A) None	0.46A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 8	HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) None None None	1.48A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 8	HIS A  94 HIS A 119 VAL A 143 LEU A 198 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None	1.40A	30.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	8 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) None	0.50A	28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 8	HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) GOL  A 303 ( 3.5A)	1.48A	28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	8 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) ZN  A 301 ( 3.2A) EZL  A 302 (-4.7A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) None	0.42A	28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	5keg	DNA DC->DU-EDITING ENZYME APOBEC-3A (Homo sapiens)	4 / 8	HIS A 119 VAL A  92 VAL A  37 LEU A  82	None	0.86A	20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	5wdh	KINESIN-LIKE PROTEIN KIFC1 (Homo sapiens)	4 / 8	HIS A 539 VAL A 541 VAL A 564 LEU A 624	None	0.84A	19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_F_EZLF302_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	8 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) None	0.45A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	1fch	PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR (Homo sapiens)	5 / 9	VAL A 453 LEU A 393 THR A 396 ALA A 400 TRP A 392	None	1.35A	20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) None	0.31A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 9	HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.3A)	1.48A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	7 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.38A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 9	HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A)	1.04A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	5 / 9	HIS A 118 HIS A 141 LEU A 222 THR A 223 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None	0.32A	27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	8 / 9	HIS A  95 HIS A  97 HIS A 120 VAL A 122 VAL A 144 LEU A 199 THR A 200 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) None	0.53A	28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	8 / 9	HIS A 111 HIS A 113 HIS A 138 VAL A 140 VAL A 161 LEU A 219 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None None	0.71A	28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) None	0.28A	28.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	5 / 9	HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A)	1.05A	28.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	7 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 142 THR A 198 TRP A 208	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None None ZN  A 261 ( 4.4A) None	0.51A	30.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	4px9	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	5 / 9	VAL A 345 VAL A 271 LEU A 235 THR A 231 ALA A 232	None None None ADP  A 601 (-4.1A) None	1.46A	22.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None None ZN  A 301 ( 4.4A) None	0.33A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 9	HIS A  96 HIS A  94 VAL A 121 LEU A 198 THR A 199	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) None None ZN  A 301 ( 4.4A)	1.30A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 9	HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199	ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None ZN  A 301 ( 4.4A)	1.04A	30.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) None	0.35A	28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 9	HIS A  96 HIS A 119 VAL A 143 LEU A 198 THR A 199	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A)	1.04A	28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	5deu	METHYLCYTOSINE DIOXYGENASE TET2, CHIMERIC CONSTRUCT (Homo sapiens)	5 / 9	HIS A1416 HIS A1881 VAL A1395 VAL A1900 ALA A1379	OGA  A2001 (-3.9A) FE  A2003 ( 3.2A) OGA  A2001 ( 4.9A) OGA  A2001 ( 4.9A) OGA  A2001 ( 4.4A)	1.46A	18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	5e7j	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	5 / 9	VAL A 345 VAL A 271 LEU A 235 THR A 231 ALA A 232	None None None AMP  A 801 (-3.5A) AMP  A 801 ( 4.3A)	1.45A	18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) ZN  A 301 ( 3.2A) EZL  A 302 (-4.7A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) None	0.38A	28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	5 / 9	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.3A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A)	1.40A	28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	8 / 9	HIS A  94 HIS A  96 HIS A 119 VAL A 121 VAL A 143 LEU A 198 THR A 199 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) None	0.40A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	5 / 9	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199	ZN  A 301 ( 3.1A) ZN  A 301 ( 3.2A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A)	1.35A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	7 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 TRP A 209	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.1A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) None	0.39A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	5 / 8	HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.3A)	1.50A	29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	6 / 8	HIS A  94 HIS A  96 HIS A 119 LEU A 198 THR A 199 TRP A 209	ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) ZN  A 561 ( 3.1A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.43A	29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	5 / 8	HIS A 118 HIS A 141 LEU A 222 THR A 223 TRP A 233	CL  A 401 (-4.2A) CL  A 401 (-4.1A) None CL  A 401 ( 4.8A) None	0.39A	27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	7 / 8	HIS A  95 HIS A  97 HIS A 120 VAL A 122 LEU A 199 THR A 200 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) ZN  A 301 ( 3.2A) 4MD  A 401 ( 4.6A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) None	0.48A	28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	7 / 8	HIS A 111 HIS A 113 HIS A 138 VAL A 140 LEU A 219 THR A 220 TRP A 230	MG  A 901 (-3.4A) MG  A 901 (-3.4A) MG  A 901 (-3.2A) None None None None	0.72A	28.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	4 / 8	HIS A 129 LEU A 235 THR A 236 TRP A 246	None	0.39A	30.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	7 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 TRP A 209	ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.1A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) None	0.43A	28.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	6 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 THR A 198 TRP A 208	ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) ZN  A 261 (-3.2A) None ZN  A 261 ( 4.4A) None	0.38A	30.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	4cns	DIHYDROPYRIMIDINASE- LIKE 3 (Homo sapiens)	4 / 8	HIS A  75 HIS A  73 HIS A 107 VAL A 109	None	0.87A	20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	4cnt	DIHYDROPYRIMIDINASE- LIKE 3 (Homo sapiens)	4 / 8	HIS A  75 HIS A  73 HIS A 107 VAL A 109	None	0.88A	17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	4p0a	E3 UBIQUITIN-PROTEIN LIGASE RNF31 (Homo sapiens)	4 / 8	HIS A 144 LEU A 151 THR A 148 ALA A 147	None	0.88A	21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	4pbx	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S (Homo sapiens)	4 / 8	HIS A 465 VAL A 486 THR A 473 TRP A 434	None	0.82A	15.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	7 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None None ZN  A 301 ( 4.4A) None	0.45A	30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	5 / 8	HIS A  94 HIS A 119 LEU A 198 THR A 199 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 (-3.1A) None ZN  A 301 ( 4.4A) None	1.43A	30.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	5aiz	ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	4 / 8	HIS A  29 LEU A  36 THR A  33 ALA A  32	ACT  A1114 (-4.3A) None ACT  A1114 ( 4.3A) None	0.90A	19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	7 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 TRP A 209	ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) None	0.44A	28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	7 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 TRP A 209	ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) ZN  A 301 ( 3.2A) EZL  A 302 (-4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) None	0.41A	28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_H_EZLH303_1 (ALPHA-CARBONIC ANHYDRASE)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	7 / 8	HIS A  94 HIS A  96 HIS A 119 VAL A 121 LEU A 198 THR A 199 TRP A 209	ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.1A) V14  A 302 (-4.7A) V14  A 302 (-3.6A) V14  A 302 (-3.2A) None	0.47A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	6 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 121 LEU A 198 THR A 200	AZM  A1400 (-3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-4.6A) AZM  A1400 (-3.9A) AZM  A1400 (-3.3A)	1.50A	15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	10 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	AZM  A1400 (-3.2A) ZN  A 901 ( 3.2A) ZN  A 901 ( 3.2A) AZM  A1400 (-4.6A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None None	0.43A	15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	6 / 12	HIS A  96 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 901 ( 3.2A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A) None None	1.36A	15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	6 / 12	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 901 ( 3.1A) ZN  A 901 ( 3.2A) AZM  A1400 ( 4.9A) AZM  A1400 (-3.9A) AZM  A1400 (-3.6A) AZM  A1400 (-3.3A)	1.43A	15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	8 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 143 LEU A 198 THR A 199 PRO A 202 TRP A 209	None ZN  A 561 ( 3.2A) ZN  A 561 ( 3.2A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None None	0.54A	19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	6 / 12	GLN A  92 HIS A  96 PHE A  91 LEU A 198 THR A 199 TRP A 209	None ZN  A 561 ( 3.2A) None PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	1.25A	19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	5 / 12	HIS A  96 VAL A 143 LEU A 198 THR A 199 PRO A 202	ZN  A 561 ( 3.2A) PPF  A 500 (-4.9A) PPF  A 500 (-3.9A) PPF  A 500 (-3.6A) None	0.94A	19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	2w2j	CARBONIC ANHYDRASE-RELATED PROTEIN (Homo sapiens)	6 / 12	HIS A 118 VAL A 157 LEU A 222 THR A 223 PRO A 226 TRP A 233	CL  A 401 (-4.2A) None None CL  A 401 ( 4.8A) None None	0.37A	22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	2xmr	PROTEIN NDRG2 (Homo sapiens)	5 / 12	VAL A 129 VAL A 153 LEU A 289 THR A 290 PRO A 286	None	1.05A	11.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	7 / 12	GLN A  93 HIS A  95 HIS A  97 PHE A 132 LEU A 199 THR A 200 PRO A 203	4MD  A 401 (-3.1A) ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) 4MD  A 401 (-4.6A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A)	0.89A	30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	9 / 12	HIS A  95 HIS A  97 VAL A 122 PHE A 132 VAL A 144 LEU A 199 THR A 200 PRO A 203 TRP A 210	ZN  A 301 ( 3.6A) ZN  A 301 ( 3.5A) 4MD  A 401 ( 4.6A) 4MD  A 401 (-4.6A) 4MD  A 401 ( 4.4A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A) None	0.45A	30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	5 / 12	HIS A  97 VAL A 122 LEU A 199 THR A 200 PRO A 203	ZN  A 301 ( 3.5A) 4MD  A 401 ( 4.6A) 4MD  A 401 (-4.2A) 4MD  A 401 (-3.2A) 4MD  A 401 ( 4.9A)	0.93A	30.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3e0l	GUANINE DEAMINASE (Homo sapiens)	5 / 12	GLN A  87 HIS A  84 HIS A  82 PHE A 108 VAL A 169	None ZN  A1452 (-3.1A) ZN  A1452 (-3.3A) None None	1.05A	10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	8 / 12	GLN A 109 HIS A 111 HIS A 113 VAL A 140 VAL A 161 LEU A 219 THR A 220 TRP A 230	None MG  A 901 (-3.4A) MG  A 901 (-3.4A) None None None None None	0.64A	16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	7 / 12	HIS A 113 VAL A 140 VAL A 161 LEU A 219 THR A 220 PRO A 223 TRP A 230	MG  A 901 (-3.4A) None None None None None None	0.75A	16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3fe4	CARBONIC ANHYDRASE 6 (Homo sapiens)	5 / 12	LEU A 219 THR A 220 THR A 221 PRO A 223 TRP A 230	None	0.48A	16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	6 / 12	HIS A 129 PHE A 166 VAL A 170 LEU A 235 THR A 236 PRO A 239	None	1.17A	12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	6 / 12	HIS A 129 VAL A 170 LEU A 235 THR A 236 PRO A 239 TRP A 246	None	0.69A	12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3jxf	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA (Homo sapiens)	5 / 12	HIS A 142 PHE A 166 VAL A 170 LEU A 235 THR A 236	None	0.86A	12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 12	GLN A  67 HIS A  96 VAL A 121 THR A 199 THR A 200 PRO A 202	None ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	1.16A	18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	7 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 121 PHE A 131 LEU A 198 THR A 199	AZM  A 264 (-4.1A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-4.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A)	1.43A	18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	11 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 121 PHE A 131 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	AZM  A 264 (-4.1A) ZN  A 263 ( 3.2A) ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-4.4A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None None	0.29A	18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 12	HIS A  94 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 263 ( 3.2A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None None	1.38A	18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 12	HIS A  96 VAL A 121 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 263 ( 3.2A) AZM  A 264 (-4.7A) AZM  A 264 (-3.4A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	1.01A	18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	6 / 12	HIS A 119 HIS A  96 VAL A 143 LEU A 198 THR A 200 PRO A 202	ZN  A 263 ( 3.1A) ZN  A 263 ( 3.2A) AZM  A 264 ( 4.9A) AZM  A 264 (-3.4A) AZM  A 264 (-3.5A) None	1.40A	18.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	9 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 121 PHE A 130 VAL A 142 THR A 198 THR A 199 PRO A 201	None ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) None None None ZN  A 261 ( 4.4A) None None	0.52A	32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	9 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 121 PHE A 130 VAL A 142 THR A 198 THR A 199 TRP A 208	None ZN  A 261 (-3.3A) ZN  A 261 (-3.3A) None None None ZN  A 261 ( 4.4A) None None	0.35A	32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	8 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 121 PHE A 131 VAL A 135 LEU A 198 THR A 199	None ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) None None None None ZN  A 301 ( 4.4A)	1.38A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	12 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 121 PHE A 131 VAL A 135 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	None ZN  A 301 (-3.2A) ZN  A 301 (-3.2A) None None None None None ZN  A 301 ( 4.4A) None None None	0.17A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	6 / 12	HIS A  94 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 (-3.2A) None ZN  A 301 ( 4.4A) None None None	1.29A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	7 / 12	HIS A  96 VAL A 143 VAL A 135 LEU A 198 THR A 199 THR A 200 PRO A 202	ZN  A 301 (-3.2A) None None None ZN  A 301 ( 4.4A) None None	1.10A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 12	GLN A  67 HIS A  96 LEU A 198 THR A 199 THR A 200	GOL  A 303 (-3.4A) ZN  A 301 ( 3.2A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A)	1.04A	24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	10 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	GOL  A 303 (-3.2A) ZN  A 301 (-3.2A) ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A) None None	0.38A	24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 12	HIS A  96 VAL A 121 LEU A 198 THR A 200 PRO A 202	ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) GOL  A 303 ( 3.5A) None	0.83A	24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	5 / 12	HIS A  96 VAL A 143 LEU A 198 THR A 199 THR A 200	ZN  A 301 ( 3.2A) 520  A 302 ( 4.9A) 520  A 302 (-3.6A) 520  A 302 (-3.4A) GOL  A 303 ( 3.5A)	0.95A	24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	9 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	EZL  A 302 (-4.3A) ZN  A 301 ( 3.3A) ZN  A 301 ( 3.3A) EZL  A 302 (-4.7A) EZL  A 302 ( 4.7A) EZL  A 302 (-3.5A) EZL  A 302 (-3.4A) EZL  A 302 (-3.9A) None	0.24A	13.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	7 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 121 VAL A 131 VAL A 143 THR A 200	V14  A 302 (-3.8A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) V14  A 302 (-4.7A) V14  A 302 ( 4.6A) None V14  A 302 (-3.5A)	1.11A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	10 / 12	GLN A  92 HIS A  94 HIS A  96 VAL A 121 VAL A 143 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	V14  A 302 (-3.8A) ZN  A 301 ( 3.2A) ZN  A 301 ( 3.2A) V14  A 302 (-4.7A) None V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None None	0.39A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BCC_A_EZLA302_1 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	6 / 12	HIS A  96 LEU A 198 THR A 199 THR A 200 PRO A 202 TRP A 209	ZN  A 301 ( 3.2A) V14  A 302 (-3.6A) V14  A 302 (-3.2A) V14  A 302 (-3.5A) None None	1.36A	33.33