POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	1k2p	TYROSINE-PROTEIN KINASE BTK (Homo sapiens)	6 / 10	ALA A 428 LYS A 430 VAL A 458 MET A 477 GLY A 480 LEU A 528	None	0.53A	33.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	1s9i	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 10	LEU A  78 ALA A  99 LYS A 101 VAL A 131 MET A 150 GLY A 153 LEU A 201	ATP  A 535 (-3.9A) ATP  A 535 (-3.6A) ATP  A 535 ( 2.5A) 5EA  A1001 (-4.5A) None ATP  A 535 ( 4.7A) ATP  A 535 (-4.8A)	0.83A	25.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	1snx	TYROSINE-PROTEIN KINASE ITK/TSK (Homo sapiens)	6 / 10	ALA A 389 LYS A 391 VAL A 419 MET A 438 GLY A 441 LEU A 489	None	0.58A	35.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	1zlt	SERINE/THREONINE-PRO TEIN KINASE CHK1 (Homo sapiens)	7 / 10	LEU A  15 ALA A  36 LYS A  38 VAL A  68 LEU A  84 GLY A  90 LEU A 137	HYM  A 400 (-4.2A) HYM  A 400 (-3.5A) HYM  A 400 (-3.2A) HYM  A 400 (-4.8A) HYM  A 400 (-4.2A) None HYM  A 400 (-4.5A)	0.66A	24.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	6 / 10	LEU X  17 ALA X  37 VAL X  67 MET X  85 GLY X  88 LEU X 137	STU  X 902 (-3.8A) STU  X 902 (-3.1A) None None STU  X 902 (-3.5A) STU  X 902 (-4.4A)	0.66A	35.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2h8h	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	7 / 10	LEU A 273 ALA A 293 LYS A 295 VAL A 323 MET A 341 GLY A 344 LEU A 393	H8H  A 534 (-3.8A) H8H  A 534 (-3.2A) H8H  A 534 (-3.7A) None None H8H  A 534 (-3.3A) H8H  A 534 (-4.5A)	0.72A	25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	6 / 10	LEU A 273 ALA A 293 VAL A 323 MET A 341 GLY A 344 LEU A 393	QUE  A   1 (-3.9A) QUE  A   1 (-3.5A) None None QUE  A   1 (-3.0A) QUE  A   1 (-4.4A)	0.62A	29.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	7 / 10	LEU A 251 ALA A 271 LYS A 273 VAL A 301 MET A 319 GLY A 322 LEU A 371	1BM  A 499 ( 3.7A) 1BM  A 499 (-3.6A) 1BM  A 499 (-3.8A) None None 1BM  A 499 (-3.5A) 1BM  A 499 (-4.4A)	0.59A	33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	7 / 10	LEU A 248 ALA A 269 LYS A 271 VAL A 299 MET A 318 GLY A 321 LEU A 370	GIN  A 600 ( 4.6A) GIN  A 600 (-3.1A) GIN  A 600 (-3.6A) GIN  A 600 (-4.6A) None None GIN  A 600 (-4.7A)	0.77A	35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	7 / 10	LEU A 251 ALA A 271 LYS A 273 VAL A 301 MET A 319 GLY A 322 LEU A 371	None 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.4A) None 1N8  A 501 ( 4.4A) 1N8  A 501 ( 3.5A) 1N8  A 501 ( 4.3A)	0.93A	40.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2ogv	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR PRECURSOR (Homo sapiens)	6 / 10	LEU A 588 ALA A 614 LYS A 616 VAL A 647 GLY A 669 LEU A 785	None	0.69A	36.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2ozo	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	6 / 10	LEU A 344 ALA A 367 LYS A 369 VAL A 399 GLY A 419 LEU A 468	ANP  A 615 (-4.4A) ANP  A 615 (-3.3A) ANP  A 615 (-3.1A) None None ANP  A 615 (-4.7A)	0.88A	24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2ozo	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	6 / 10	LEU A 344 ALA A 367 LYS A 369 VAL A 399 GLY A 420 LEU A 468	ANP  A 615 (-4.4A) ANP  A 615 (-3.3A) ANP  A 615 (-3.1A) None ANP  A 615 ( 3.9A) ANP  A 615 (-4.7A)	0.65A	24.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2r4b	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	8 / 10	LEU A 724 ALA A 749 LYS A 751 VAL A 781 LEU A 798 MET A 799 GLY A 802 LEU A 850	GW7  A   1 ( 4.2A) GW7  A   1 (-3.3A) GW7  A   1 (-3.9A) GW7  A   1 ( 4.7A) GW7  A   1 (-4.5A) None GW7  A   1 (-3.6A) GW7  A   1 (-4.2A)	0.98A	32.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2xk9	CHECKPOINT KINASE 2 (Homo sapiens)	7 / 10	LEU A 226 ALA A 247 LEU A 301 LEU A 303 MET A 304 GLY A 307 LEU A 354	XK9  A1511 (-3.8A) XK9  A1511 ( 4.1A) XK9  A1511 (-4.6A) XK9  A1511 (-4.1A) None XK9  A1511 ( 3.7A) XK9  A1511 (-4.6A)	0.60A	25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	6 / 10	LEU A  68 ALA A  92 LYS A  94 VAL A 125 LEU A 141 GLY A 147	STU  A   1 (-3.8A) STU  A   1 (-3.3A) STU  A   1 (-2.8A) None STU  A   1 ( 4.6A) STU  A   1 ( 3.9A)	0.85A	24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	6 / 10	LEU A  68 ALA A  92 VAL A 125 LEU A 141 GLY A 147 LEU A 194	STU  A   1 (-3.8A) STU  A   1 (-3.3A) None STU  A   1 ( 4.6A) STU  A   1 ( 3.9A) STU  A   1 (-4.6A)	0.87A	24.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	2z8c	INSULIN RECEPTOR (Homo sapiens)	8 / 10	ARG A1000 LEU A1002 ALA A1028 LYS A1030 VAL A1060 LEU A1078 MET A1079 GLY A1082	None S91  A   1 ( 4.1A) S91  A   1 (-3.2A) S91  A   1 ( 4.2A) None S91  A   1 (-4.7A) None S91  A   1 (-3.3A)	0.66A	44.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	6 / 10	ALA A 220 LYS A 222 VAL A 249 MET A 269 GLY A 272 LEU A 321	None	0.50A	33.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3fme	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 (Homo sapiens)	6 / 10	LEU A  59 ALA A  80 VAL A 113 LEU A 131 MET A 132 LEU A 186	STU  A   1 (-3.8A) STU  A   1 (-3.4A) None STU  A   1 (-4.6A) None STU  A   1 (-4.4A)	0.72A	26.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3fzp	PROTEIN TYROSINE KINASE 2 BETA (Homo sapiens)	7 / 10	LEU A 431 ALA A 455 LYS A 457 VAL A 487 LEU A 504 GLY A 508 LEU A 556	AGS  A 999 ( 4.4A) AGS  A 999 (-3.6A) AGS  A 999 (-2.5A) None AGS  A 999 (-4.4A) None AGS  A 999 (-4.5A)	0.99A	35.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3i6u	SERINE/THREONINE-PRO TEIN KINASE CHK2 (Homo sapiens)	7 / 10	LEU A 226 ALA A 247 LEU A 301 LEU A 303 MET A 304 GLY A 307 LEU A 354	None	0.85A	23.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 10	ARG A1003 LEU A1005 ALA A1031 VAL A1063 LEU A1081 MET A1082 GLY A1085	None None None CCX  A   1 (-4.1A) None None None	0.54A	39.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3nuu	PKB-LIKE (Homo sapiens)	6 / 10	LEU A  88 ALA A 109 LYS A 111 LEU A 159 GLY A 165 LEU A 212	JOZ  A 361 (-4.1A) JOZ  A 361 (-3.4A) SO4  A   5 (-2.8A) JOZ  A 361 (-4.0A) None None	0.81A	23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	7 / 10	ALA A 213 VAL A 247 LEU A 263 LEU A 265 MET A 266 GLY A 268 LEU A 318	AMP  A 577 (-3.4A) None AMP  A 577 ( 4.7A) AMP  A 577 ( 4.9A) None None AMP  A 577 (-4.8A)	1.11A	21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	7 / 10	ARG A 190 LEU A 192 ALA A 213 LYS A 215 LEU A 263 GLY A 269 LEU A 318	None AMP  A 577 ( 4.3A) AMP  A 577 (-3.4A) AMP  A 577 (-2.8A) AMP  A 577 ( 4.7A) None AMP  A 577 (-4.8A)	1.18A	21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	9 / 10	LEU A 192 ALA A 213 LYS A 215 VAL A 247 LEU A 263 LEU A 265 MET A 266 GLY A 269 LEU A 318	AMP  A 577 ( 4.3A) AMP  A 577 (-3.4A) AMP  A 577 (-2.8A) None AMP  A 577 ( 4.7A) AMP  A 577 ( 4.9A) None None AMP  A 577 (-4.8A)	0.60A	21.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	6 / 10	LEU A 726 ALA A 751 LEU A 800 MET A 801 GLY A 804 LEU A 852	03Q  A   1 (-3.8A) 03Q  A   1 (-3.1A) 03Q  A   1 (-4.6A) None 03Q  A   1 ( 3.9A) 03Q  A   1 (-4.4A)	0.65A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3sxs	CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX (Homo sapiens)	6 / 10	LEU A 423 ALA A 443 LYS A 445 VAL A 473 GLY A 495 LEU A 543	PP2  A   1 (-4.1A) PP2  A   1 (-3.2A) PP2  A   1 (-4.5A) None PP2  A   1 ( 4.2A) PP2  A   1 (-4.6A)	0.72A	33.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3v5q	NT-3 GROWTH FACTOR RECEPTOR (Homo sapiens)	7 / 10	ARG A 542 LEU A 544 ALA A 570 VAL A 601 MET A 620 GLY A 623 LEU A 686	None 0F4  A 902 ( 4.2A) 0F4  A 902 (-3.2A) None None 0F4  A 902 (-3.4A) 0F4  A 902 (-4.5A)	0.64A	37.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3vn9	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 (Homo sapiens)	6 / 10	LEU A  59 ALA A  80 VAL A 113 LEU A 131 MET A 132 LEU A 186	None ANK  A 401 (-3.0A) None None None ANK  A 401 ( 4.9A)	0.64A	26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3w18	AURORA KINASE A (Homo sapiens)	7 / 10	ARG A 137 LEU A 139 ALA A 160 LYS A 162 LEU A 210 GLY A 216 LEU A 263	N13  A 501 ( 4.6A) N13  A 501 (-3.7A) N13  A 501 ( 4.1A) N13  A 501 (-2.9A) N13  A 501 ( 4.8A) N13  A 501 (-3.5A) N13  A 501 (-4.5A)	1.17A	24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3wig	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 (Homo sapiens)	7 / 10	LEU A  75 ALA A  96 LYS A  98 VAL A 128 MET A 147 GLY A 150 LEU A 198	ANP  A 401 (-3.8A) ANP  A 401 (-3.2A) ANP  A 401 (-2.7A) CHU  A 403 (-4.2A) None ANP  A 401 ( 4.3A) ANP  A 401 (-4.8A)	0.65A	24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	6 / 10	ALA A1978 LEU A2026 LEU A2028 MET A2029 GLY A2031 LEU A2086	VGH  A3000 (-3.4A) VGH  A3000 ( 4.2A) VGH  A3000 ( 4.8A) None None VGH  A3000 (-4.3A)	0.90A	45.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	7 / 10	LEU A1951 ALA A1978 LEU A2026 LEU A2028 MET A2029 GLY A2032 LEU A2086	VGH  A3000 ( 4.4A) VGH  A3000 (-3.4A) VGH  A3000 ( 4.2A) VGH  A3000 ( 4.8A) None VGH  A3000 (-3.5A) VGH  A3000 (-4.3A)	0.44A	45.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	7 / 10	LEU A1951 ALA A1978 LYS A1980 LEU A2026 LEU A2028 GLY A2032 LEU A2086	VGH  A3000 ( 4.4A) VGH  A3000 (-3.4A) VGH  A3000 ( 4.7A) VGH  A3000 ( 4.2A) VGH  A3000 ( 4.8A) VGH  A3000 (-3.5A) VGH  A3000 (-4.3A)	0.54A	45.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4a4l	SERINE/THREONINE-PRO TEIN KINASE PLK1 (Homo sapiens)	7 / 10	ARG A  57 LEU A  59 ALA A  80 LYS A  82 VAL A 114 LEU A 130 LEU A 132	939  A1331 (-3.9A) 939  A1331 (-3.7A) 939  A1331 (-3.5A) 939  A1331 (-2.6A) None 939  A1331 ( 4.7A) 939  A1331 (-4.4A)	0.76A	25.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4agd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	6 / 10	LEU A 840 ALA A 866 LYS A 868 VAL A 899 GLY A 922 LEU A1035	B49  A2000 (-3.7A) B49  A2000 (-3.5A) B49  A2000 (-3.0A) B49  A2000 ( 4.6A) B49  A2000 ( 3.7A) B49  A2000 (-4.5A)	0.78A	33.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4at3	BDNF/NT-3 GROWTH FACTORS RECEPTOR (Homo sapiens)	7 / 10	ARG A 558 LEU A 560 ALA A 586 VAL A 617 MET A 636 GLY A 639 LEU A 699	None LTI  A1839 ( 4.2A) LTI  A1839 (-3.3A) None None LTI  A1839 (-3.4A) LTI  A1839 (-4.2A)	0.64A	36.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4b6l	SERINE/THREONINE-PRO TEIN KINASE PLK3 (Homo sapiens)	7 / 10	ARG A  66 LEU A  68 ALA A  89 LYS A  91 VAL A 123 LEU A 139 LEU A 141	9ZP  A1333 (-3.3A) 9ZP  A1333 (-3.9A) 9ZP  A1333 (-3.5A) None 9ZP  A1333 (-4.4A) 9ZP  A1333 (-3.8A) 9ZP  A1333 (-4.7A)	0.72A	24.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4e93	TYROSINE-PROTEIN KINASE FES/FPS (Homo sapiens)	6 / 10	ALA A 588 LYS A 590 VAL A 620 LEU A 638 GLY A 642 LEU A 690	GUI  A 901 (-3.4A) GUI  A 901 (-2.8A) None GUI  A 901 (-4.4A) GUI  A 901 (-3.5A) GUI  A 901 (-4.3A)	0.53A	34.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4f0i	HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR (Homo sapiens)	6 / 10	LEU A 515 ALA A 541 VAL A 572 MET A 591 GLY A 594 LEU A 656	None	0.49A	37.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4f4p	TYROSINE-PROTEIN KINASE SYK (Homo sapiens)	6 / 10	LEU A 377 ALA A 400 LYS A 402 VAL A 433 GLY A 454 LEU A 501	0SB  A 701 ( 3.9A) 0SB  A 701 (-3.3A) 0SB  A 701 ( 4.8A) None 0SB  A 701 (-3.5A) 0SB  A 701 (-4.4A)	0.43A	32.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4fl3	TYROSINE-PROTEIN KINASE SYK (Homo sapiens)	6 / 10	LEU A 377 ALA A 400 LYS A 402 VAL A 433 GLY A 454 LEU A 501	ANP  A 701 ( 4.6A) ANP  A 701 (-3.3A) ANP  A 701 (-2.7A) ANP  A 701 (-4.8A) ANP  A 701 ( 4.2A) ANP  A 701 (-4.5A)	0.60A	21.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	7 / 10	ALA A1148 VAL A1180 LEU A1196 LEU A1198 MET A1199 GLY A1201 LEU A1256	0UV  A1501 (-3.4A) 0UV  A1501 ( 4.9A) 0UV  A1501 (-3.7A) 0UV  A1501 ( 4.8A) None 0UV  A1501 (-4.4A) 0UV  A1501 (-4.6A)	0.97A	99.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	9 / 10	LEU A1122 ALA A1148 LYS A1150 VAL A1180 LEU A1196 LEU A1198 MET A1199 GLY A1202 LEU A1256	0UV  A1501 (-3.8A) 0UV  A1501 (-3.4A) 0UV  A1501 (-3.7A) 0UV  A1501 ( 4.9A) 0UV  A1501 (-3.7A) 0UV  A1501 ( 4.8A) None 0UV  A1501 (-3.6A) 0UV  A1501 (-4.6A)	0.42A	99.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4hzs	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	6 / 10	LEU A 132 ALA A 156 LYS A 158 LEU A 207 GLY A 211 LEU A 259	None	0.66A	32.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4id7	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	6 / 10	LEU A 132 ALA A 156 LYS A 158 LEU A 207 GLY A 211 LEU A 259	1G0  A 401 ( 4.5A) 1G0  A 401 (-3.6A) 1G0  A 401 (-3.7A) 1G0  A 401 ( 4.9A) 1G0  A 401 ( 4.5A) 1G0  A 401 (-4.6A)	0.56A	33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4idt	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 (Homo sapiens)	6 / 10	LEU A 406 ALA A 427 LYS A 429 VAL A 453 LEU A 471 LEU A 522	T28  A 701 (-3.8A) T28  A 701 (-3.0A) T28  A 701 ( 3.8A) None T28  A 701 ( 4.8A) T28  A 701 (-3.9A)	0.84A	24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4idt	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 (Homo sapiens)	6 / 10	LEU A 406 ALA A 427 VAL A 453 LEU A 471 GLY A 475 LEU A 522	T28  A 701 (-3.8A) T28  A 701 (-3.0A) None T28  A 701 ( 4.8A) T28  A 701 ( 3.0A) T28  A 701 (-3.9A)	0.87A	24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4k11	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	7 / 10	LEU A 273 ALA A 293 LYS A 295 VAL A 323 MET A 341 GLY A 344 LEU A 393	0J9  A 601 (-4.0A) 0J9  A 601 (-3.3A) 0J9  A 601 ( 4.7A) None None 0J9  A 601 ( 4.1A) 0J9  A 601 (-4.5A)	0.63A	28.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4lg4	SERINE/THREONINE-PRO TEIN KINASE 3 (Homo sapiens)	6 / 10	LEU A  33 ALA A  54 LYS A  56 VAL A  83 GLY A 105 LEU A 153	GOL  A 404 ( 3.6A) GOL  A 404 ( 3.1A) GOL  A 403 ( 4.6A) GOL  A 403 (-4.1A) GOL  A 404 (-3.6A) GOL  A 403 ( 4.4A)	0.54A	25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4mk0	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	8 / 10	ALA A 218 LYS A 220 VAL A 255 LEU A 271 LEU A 273 MET A 274 GLY A 276 LEU A 324	29X  A 702 (-3.1A) 29X  A 702 (-3.6A) 29X  A 702 (-4.8A) 29X  A 702 ( 4.7A) 29X  A 702 (-4.6A) None None 29X  A 702 (-4.6A)	0.88A	19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4mk0	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	8 / 10	ALA A 218 LYS A 220 VAL A 255 LEU A 271 LEU A 273 MET A 274 GLY A 277 LEU A 324	29X  A 702 (-3.1A) 29X  A 702 (-3.6A) 29X  A 702 (-4.8A) 29X  A 702 ( 4.7A) 29X  A 702 (-4.6A) None None 29X  A 702 (-4.6A)	0.76A	19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	8 / 10	ARG A  44 LEU A  46 ALA A  67 LYS A  69 VAL A  99 LEU A 125 GLY A 128 LEU A 180	None SIN  A 401 ( 3.9A) SIN  A 401 ( 3.7A) None None SIN  A 401 ( 4.8A) SIN  A 401 (-3.5A) SIN  A 401 ( 4.5A)	0.73A	24.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4rt7	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	6 / 10	LEU A 616 ALA A 642 LYS A 644 VAL A 675 GLY A 697 LEU A 818	P30  A1001 (-3.8A) P30  A1001 (-3.4A) P30  A1001 (-3.4A) None P30  A1001 (-3.4A) P30  A1001 (-4.6A)	0.72A	32.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4tnb	G PROTEIN-COUPLED RECEPTOR KINASE 5 (Homo sapiens)	7 / 10	ARG A 190 LEU A 192 ALA A 213 LEU A 263 MET A 266 GLY A 268 LEU A 318	None SGV  A 601 (-4.1A) SGV  A 601 (-3.3A) SGV  A 601 (-4.5A) None None SGV  A 601 (-4.9A)	1.18A	19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4tnb	G PROTEIN-COUPLED RECEPTOR KINASE 5 (Homo sapiens)	7 / 10	ARG A 190 LEU A 192 ALA A 213 VAL A 247 LEU A 263 MET A 266 LEU A 318	None SGV  A 601 (-4.1A) SGV  A 601 (-3.3A) None SGV  A 601 (-4.5A) None SGV  A 601 (-4.9A)	0.86A	19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4tnb	G PROTEIN-COUPLED RECEPTOR KINASE 5 (Homo sapiens)	7 / 10	LEU A 192 ALA A 213 LYS A 215 VAL A 247 LEU A 263 MET A 266 LEU A 318	SGV  A 601 (-4.1A) SGV  A 601 (-3.3A) SGV  A 601 ( 4.2A) None SGV  A 601 (-4.5A) None SGV  A 601 (-4.9A)	0.78A	19.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	7 / 10	LEU B 267 ALA B 288 LYS B 290 VAL B 318 MET B 337 GLY B 340 LEU B 389	1N1  B 601 (-3.7A) 1N1  B 601 (-3.5A) 1N1  B 601 (-4.6A) 1N1  B 601 ( 4.3A) None 1N1  B 601 (-3.5A) 1N1  B 601 (-4.3A)	0.59A	32.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4yhj	G PROTEIN-COUPLED RECEPTOR KINASE 4 (Homo sapiens)	7 / 10	ARG A 191 LEU A 193 ALA A 214 LYS A 216 VAL A 248 LEU A 264 LEU A 319	None AN2  A 601 ( 4.2A) AN2  A 601 (-3.6A) AN2  A 601 ( 3.9A) None AN2  A 601 ( 4.8A) None	1.07A	22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4yhj	G PROTEIN-COUPLED RECEPTOR KINASE 4 (Homo sapiens)	7 / 10	ARG A 191 LEU A 193 LYS A 216 VAL A 248 LEU A 264 GLY A 270 LEU A 319	None AN2  A 601 ( 4.2A) AN2  A 601 ( 3.9A) None AN2  A 601 ( 4.8A) None None	1.22A	22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4yhj	G PROTEIN-COUPLED RECEPTOR KINASE 4 (Homo sapiens)	7 / 10	LEU A 193 ALA A 214 LYS A 216 VAL A 248 LEU A 264 MET A 267 LEU A 319	AN2  A 601 ( 4.2A) AN2  A 601 (-3.6A) AN2  A 601 ( 3.9A) None AN2  A 601 ( 4.8A) None None	0.62A	22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	4yhj	G PROTEIN-COUPLED RECEPTOR KINASE 4 (Homo sapiens)	7 / 10	LEU A 193 LYS A 216 VAL A 248 LEU A 264 MET A 267 GLY A 270 LEU A 319	AN2  A 601 ( 4.2A) AN2  A 601 ( 3.9A) None AN2  A 601 ( 4.8A) None None None	0.84A	22.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	6 / 10	LEU A 599 ALA A 625 LYS A 627 VAL A 658 GLY A 680 LEU A 825	748  A1001 (-3.8A) 748  A1001 (-3.7A) 748  A1001 (-4.0A) 748  A1001 ( 4.8A) 748  A1001 ( 4.0A) 748  A1001 (-4.3A)	0.93A	35.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	5j9z	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	7 / 10	LEU A 718 ALA A 743 LYS A 745 LEU A 792 MET A 793 GLY A 796 LEU A 844	6HJ  A1101 ( 4.6A) 6HJ  A1101 (-3.1A) 6HJ  A1101 (-4.2A) 6HJ  A1101 ( 4.9A) None 6HJ  A1101 ( 4.5A) 6HJ  A1101 ( 4.8A)	0.39A	31.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	5jzn	SERINE/THREONINE-PRO TEIN KINASE DCLK1 (Homo sapiens)	7 / 10	ARG A 394 ALA A 417 LYS A 419 VAL A 449 LEU A 467 GLY A 471 LEU A 518	None GUI  A 701 ( 3.9A) GUI  A 701 (-3.1A) None GUI  A 701 ( 4.7A) GUI  A 701 (-3.6A) GUI  A 701 (-4.4A)	0.68A	26.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 10	LEU A 593 ALA A 617 LYS A 619 LEU A 671 MET A 674 GLY A 677	7AE  A1000 ( 3.9A) 7AE  A1000 (-3.3A) 7AE  A1000 (-3.1A) 7AE  A1000 (-3.7A) None 7AE  A1000 ( 3.7A)	0.47A	35.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	5u6b	TYROSINE-PROTEIN KINASE RECEPTOR UFO (Homo sapiens)	6 / 10	LEU A 542 ALA A 565 LYS A 567 LEU A 620 MET A 623 GLY A 626	7YS  A9001 (-4.1A) 7YS  A9001 (-3.3A) None 7YS  A9001 (-4.2A) 7YS  A9001 (-4.7A) 7YS  A9001 (-3.4A)	0.68A	38.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	5u7q	RHO-ASSOCIATED PROTEIN KINASE 2 (Homo sapiens)	6 / 10	ALA A 119 LYS A 121 VAL A 153 MET A 172 GLY A 175 LEU A 221	None	0.61A	25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	5uuu	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	8 / 10	ALA A 218 LYS A 220 VAL A 255 LEU A 271 LEU A 273 MET A 274 GLY A 277 LEU A 324	QRW  A 601 (-3.4A) QRW  A 601 (-3.0A) None QRW  A 601 ( 4.9A) None MES  A 604 (-3.9A) None None	0.70A	21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	5uuu	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	7 / 10	ALA A 218 VAL A 255 LEU A 271 LEU A 273 MET A 274 GLY A 276 LEU A 324	QRW  A 601 (-3.4A) None QRW  A 601 ( 4.9A) None MES  A 604 (-3.9A) None None	0.97A	21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	5w5j	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2 (Homo sapiens)	6 / 10	LEU A  24 ALA A  45 LYS A  47 MET A  98 GLY A 101 LEU A 153	9WS  A 401 ( 4.2A) 9WS  A 401 (-3.3A) 9WS  A 401 (-3.3A) None 9WS  A 401 ( 4.3A) 9WS  A 401 (-4.6A)	0.69A	27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	6ao5	SERINE/THREONINE-PRO TEIN KINASE 3 (Homo sapiens)	6 / 10	LEU A  33 ALA A  54 LYS A  56 VAL A  83 GLY A 105 LEU A 153	ANP  A 501 ( 3.8A) ANP  A 501 ( 3.7A) ANP  A 501 (-2.4A) None ANP  A 501 ( 4.0A) ANP  A 501 (-4.6A)	0.83A	24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 10	ALA A 192 LYS A 194 VAL A 249 LEU A 269 GLY A 273 LEU A 319	BI9  A 501 (-3.3A) NH4  A 506 ( 4.4A) None BI9  A 501 (-4.4A) BI9  A 501 (-3.3A) BI9  A 501 (-4.7A)	0.48A	13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	6c7y	TYROSINE-PROTEIN KINASE JAK1 (Homo sapiens)	7 / 10	ARG A 879 LEU A 881 ALA A 906 LYS A 908 VAL A 938 GLY A 962 LEU A1010	None ADP  A1201 ( 4.5A) ADP  A1201 (-3.4A) ADP  A1201 (-2.8A) None ADP  A1201 ( 4.1A) ADP  A1201 (-4.5A)	0.76A	15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	6ccf	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 1 (Homo sapiens)	6 / 10	ALA A 155 LYS A 157 VAL A 212 LEU A 232 GLY A 236 LEU A 282	H1N  A 501 (-3.4A) H1N  A 501 (-2.8A) H1N  A 501 (-4.9A) H1N  A 501 (-4.3A) H1N  A 501 (-3.6A) H1N  A 501 (-4.8A)	0.55A	13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	6cz4	PROTEIN-TYROSINE KINASE 6 (Homo sapiens)	7 / 10	ARG A 195 LEU A 197 ALA A 217 LEU A 266 MET A 267 GLY A 270 LEU A 319	None FKY  A9001 (-4.1A) FKY  A9001 (-3.3A) FKY  A9001 (-4.4A) None FKY  A9001 (-3.3A) FKY  A9001 ( 4.9A)	0.83A	16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	1bp1	BACTERICIDAL/PERMEAB ILITY-INCREASING PROTEIN (Homo sapiens)	5 / 12	LEU A 256 GLY A 257 GLY A 450 LEU A 427 ALA A 249	None	0.87A	12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	1rjb	FL CYTOKINE RECEPTOR (Homo sapiens)	5 / 12	LEU A 616 GLY A 617 VAL A 624 ALA A 642 PHE A 691	None	0.45A	12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	1ua2	CELL DIVISION PROTEIN KINASE 7 (Homo sapiens)	6 / 12	LEU A  18 GLY A  19 VAL A  26 ALA A  39 PHE A  91 ALA A 154	ATP  A 381 (-4.4A) ATP  A 381 ( 3.9A) ATP  A 381 (-4.0A) ATP  A 381 (-3.6A) None None	0.46A	17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2eu9	DUAL SPECIFICITY PROTEIN KINASE CLK3 (Homo sapiens)	6 / 12	LEU A 162 GLY A 163 VAL A 170 ALA A 184 PHE A 236 ALA A 319	None	0.53A	13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2h8h	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	5 / 12	LEU A 273 GLY A 274 VAL A 281 ALA A 293 ALA A 403	H8H  A 534 (-3.8A) H8H  A 534 ( 3.8A) H8H  A 534 (-4.4A) H8H  A 534 (-3.2A) H8H  A 534 ( 4.0A)	0.56A	11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2h8h	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	5 / 12	LEU A 273 GLY A 274 VAL A 281 GLY A 344 ALA A 403	H8H  A 534 (-3.8A) H8H  A 534 ( 3.8A) H8H  A 534 (-4.4A) H8H  A 534 (-3.3A) H8H  A 534 ( 4.0A)	0.70A	11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	5 / 12	LEU A 273 GLY A 274 VAL A 281 ALA A 293 ALA A 403	QUE  A   1 (-3.9A) QUE  A   1 ( 4.2A) QUE  A   1 ( 4.8A) QUE  A   1 (-3.5A) QUE  A   1 ( 4.5A)	0.63A	13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	5 / 12	LEU A 273 GLY A 274 VAL A 281 GLY A 344 ALA A 403	QUE  A   1 (-3.9A) QUE  A   1 ( 4.2A) QUE  A   1 ( 4.8A) QUE  A   1 (-3.0A) QUE  A   1 ( 4.5A)	0.76A	13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	5 / 12	LEU A 251 GLY A 252 VAL A 259 ALA A 271 ALA A 381	1BM  A 499 ( 3.7A) None 1BM  A 499 ( 4.8A) 1BM  A 499 (-3.6A) 1BM  A 499 ( 3.7A)	0.37A	14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	5 / 12	LEU A 251 GLY A 252 VAL A 259 GLY A 322 ALA A 381	1BM  A 499 ( 3.7A) None 1BM  A 499 ( 4.8A) 1BM  A 499 (-3.5A) 1BM  A 499 ( 3.7A)	0.54A	14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2hw6	MAP KINASE-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 1 (Homo sapiens)	5 / 12	LEU A  55 GLY A  56 VAL A  63 ALA A  76 PHE A 124	None	0.51A	12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2jgz	CELL DIVISION PROTEIN KINASE 2 (Homo sapiens)	5 / 12	GLY A  11 VAL A  18 ALA A  31 PHE A  80 ALA A 144	None	0.42A	15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	5 / 12	LEU A 251 GLY A 252 VAL A 259 ALA A 271 ALA A 381	None None None 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.3A)	0.73A	12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2ozo	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	5 / 12	LEU A 344 GLY A 345 VAL A 352 ALA A 367 GLY A 418	ANP  A 615 (-4.4A) ANP  A 615 ( 4.4A) ANP  A 615 (-4.5A) ANP  A 615 (-3.3A) ANP  A 615 ( 4.0A)	0.60A	8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	3b2t	FIBROBLAST GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	5 / 12	LEU A 487 GLY A 488 VAL A 495 ALA A 515 ALA A 643	M33  A1996 (-4.0A) M33  A1996 ( 3.8A) M33  A1996 ( 4.7A) M33  A1996 (-3.3A) None	0.52A	13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	3mtl	CELL DIVISION PROTEIN KINASE 16 (Homo sapiens)	5 / 12	LEU A 171 GLY A 172 VAL A 179 ALA A 192 PHE A 240	FEF  A 668 ( 3.8A) FEF  A 668 ( 4.2A) FEF  A 668 (-4.9A) FEF  A 668 (-3.3A) FEF  A 668 ( 4.3A)	0.43A	13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	3sxs	CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX (Homo sapiens)	5 / 12	LEU A 423 GLY A 424 VAL A 431 ALA A 443 GLY A 495	PP2  A   1 (-4.1A) PP2  A   1 ( 4.1A) PP2  A   1 (-4.5A) PP2  A   1 (-3.2A) PP2  A   1 ( 4.2A)	0.60A	14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	3zzw	TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR2 (Homo sapiens)	5 / 12	LEU A 479 GLY A 480 VAL A 487 ALA A 505 PHE A 553	None	0.59A	14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4af3	AURORA KINASE B (Homo sapiens)	5 / 12	ARG A  81 LEU A  83 GLY A  84 VAL A  91 ALA A 104	None VX6  A 500 (-3.8A) VX6  A 500 ( 4.1A) VX6  A 500 ( 4.8A) VX6  A 500 (-3.4A)	0.75A	12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4aw5	EPHRIN TYPE-B RECEPTOR 4 (Homo sapiens)	5 / 12	LEU A 350 VAL A 347 ALA A 201 GLY A 195 LEU A 325	None	0.96A	12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4bc6	SERINE/THREONINE-PRO TEIN KINASE 10 (Homo sapiens)	5 / 12	LEU A  42 GLY A  43 VAL A  50 ALA A  63 ALA A 174	XZN  A1317 (-3.6A) XZN  A1317 ( 4.9A) XZN  A1317 ( 4.7A) XZN  A1317 (-3.5A) XZN  A1317 ( 4.3A)	0.44A	13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	5 / 12	LEU A 616 GLY A 617 VAL A 624 ALA A 653 ALA A 783	None None DI1  A1000 (-4.8A) DI1  A1000 (-3.6A) DI1  A1000 (-3.7A)	0.48A	11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4f0i	HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR (Homo sapiens)	5 / 12	LEU A 515 GLY A 516 VAL A 523 ALA A 541 PHE A 588	None	0.25A	14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4f4p	TYROSINE-PROTEIN KINASE SYK (Homo sapiens)	5 / 12	LEU A 377 GLY A 378 VAL A 385 ALA A 400 GLY A 454	0SB  A 701 ( 3.9A) 0SB  A 701 (-3.6A) 0SB  A 701 (-4.0A) 0SB  A 701 (-3.3A) 0SB  A 701 (-3.5A)	0.56A	12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4k11	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	5 / 12	LEU A 273 GLY A 274 VAL A 281 ALA A 293 ALA A 403	0J9  A 601 (-4.0A) 0J9  A 601 ( 4.0A) 0J9  A 601 (-4.4A) 0J9  A 601 (-3.3A) 0J9  A 601 (-3.5A)	0.34A	12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4k11	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	5 / 12	LEU A 273 GLY A 274 VAL A 281 GLY A 344 ALA A 403	0J9  A 601 (-4.0A) 0J9  A 601 ( 4.0A) 0J9  A 601 (-4.4A) 0J9  A 601 ( 4.1A) 0J9  A 601 (-3.5A)	0.64A	12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4lg4	SERINE/THREONINE-PRO TEIN KINASE 3 (Homo sapiens)	5 / 12	LEU A  33 GLY A  34 VAL A  41 ALA A  54 ALA A 163	GOL  A 404 ( 3.6A) None GOL  A 404 (-4.5A) GOL  A 404 ( 3.1A) GOL  A 403 ( 3.0A)	0.34A	11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4nsp	ENDONUCLEASE V (Homo sapiens)	5 / 12	LEU A 124 GLY A  50 VAL A 236 GLY A 152 LEU A 223	None	0.97A	15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4q9z	HUMAN PROTEIN KINASE C THETA (Homo sapiens)	5 / 12	LEU A 386 GLY A 387 VAL A 394 ALA A 407 ALA A 521	PZW  A 801 (-3.9A) PZW  A 801 ( 3.8A) PZW  A 801 (-4.6A) PZW  A 801 (-3.5A) PZW  A 801 ( 4.6A)	0.21A	12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4ra4	PROTEIN KINASE C (Homo sapiens)	5 / 12	LEU A 345 GLY A 346 VAL A 353 ALA A 366 ALA A 480	3KZ  A 701 ( 4.1A) 3KZ  A 701 (-3.3A) 3KZ  A 701 (-3.9A) 3KZ  A 701 (-3.4A) 3KZ  A 701 ( 4.8A)	0.33A	12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4red	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (Homo sapiens)	5 / 12	LEU A  24 GLY A  25 VAL A  32 ALA A  45 ALA A 158	None	0.70A	13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4rt7	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	5 / 12	LEU A 616 GLY A 617 VAL A 624 ALA A 642 PHE A 691	P30  A1001 (-3.8A) None None P30  A1001 (-3.4A) P30  A1001 (-3.7A)	0.19A	10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4xcu	FIBROBLAST GROWTH FACTOR RECEPTOR 4 (Homo sapiens)	5 / 12	LEU A 473 GLY A 474 VAL A 481 ALA A 501 ALA A 629	40M  A1002 ( 4.6A) None 40M  A1002 ( 4.5A) 40M  A1002 ( 4.1A) 40M  A1002 (-3.0A)	0.55A	13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4xuf	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	5 / 12	LEU A 616 GLY A 617 VAL A 624 ALA A 642 PHE A 691	P30  A1001 (-4.0A) None P30  A1001 ( 4.8A) P30  A1001 (-3.5A) P30  A1001 ( 4.3A)	0.47A	13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4yc6	CYCLIN-DEPENDENT KINASE 1 (Homo sapiens)	5 / 12	GLY A  11 VAL A  18 ALA A  31 PHE A  80 ALA A 145	None	0.50A	12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5a46	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens)	5 / 12	LEU A 484 GLY A 485 VAL A 492 ALA A 512 ALA A 640	38O  A1769 (-3.2A) 38O  A1769 ( 4.7A) 38O  A1769 (-4.5A) 38O  A1769 (-3.6A) EDO  A1766 ( 4.4A)	0.47A	12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5f1z	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	5 / 12	ARG A 901 LEU A 903 GLY A 904 VAL A 911 ALA A 928	5U3  A1200 ( 4.1A) 5U3  A1200 (-3.8A) 5U3  A1200 ( 3.7A) 5U3  A1200 ( 4.4A) 5U3  A1200 (-3.5A)	0.46A	16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5idn	CYCLIN-DEPENDENT KINASE 8 (Homo sapiens)	5 / 12	GLY A  28 VAL A  35 ALA A  50 PHE A  97 ALA A 172	6A7  A 401 (-3.6A) 6A7  A 401 ( 4.5A) 6A7  A 401 (-3.3A) 6A7  A 401 (-3.8A) 6A7  A 401 ( 4.1A)	0.37A	14.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	10 / 12	ARG A  96 LEU A  98 GLY A  99 VAL A 106 ALA A 119 PHE A 177 GLY A 181 VAL A 235 TYR A 239 ALA A 540	None W4A  A 716 (-4.1A) W4A  A 716 ( 4.0A) W4A  A 716 ( 4.7A) W4A  A 716 ( 3.9A) DMS  A 717 ( 3.9A) W4A  A 716 (-3.8A) W4A  A 716 ( 4.9A) W4A  A 716 (-4.8A) DMS  A 717 ( 4.5A)	0.46A	86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	7 / 12	ARG A  96 PHE A 177 GLY A 181 HIS A 182 VAL A 235 TYR A 239 ALA A 540	None DMS  A 717 ( 3.9A) W4A  A 716 (-3.8A) W4A  A 716 ( 3.6A) W4A  A 716 ( 4.9A) W4A  A 716 (-4.8A) DMS  A 717 ( 4.5A)	0.80A	86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	6 / 12	LEU A  98 GLY A  99 VAL A 106 ALA A 119 PHE A 177 VAL A 240	W4A  A 716 (-4.1A) W4A  A 716 ( 4.0A) W4A  A 716 ( 4.7A) W4A  A 716 ( 3.9A) DMS  A 717 ( 3.9A) None	1.22A	86.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	5 / 12	LEU A 593 GLY A 594 VAL A 601 ALA A 617 ALA A 740	7AE  A1000 ( 3.9A) 7AE  A1000 ( 4.2A) 7AE  A1000 ( 4.9A) 7AE  A1000 (-3.3A) 7AE  A1000 ( 3.7A)	0.28A	14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5tur	SERINE/THREONINE-PRO TEIN KINASE PIM-1 (Homo sapiens)	5 / 12	LEU A  44 GLY A  45 VAL A  52 ALA A  65 VAL A 126	None None 7LK  A 401 (-4.9A) 7LK  A 401 (-3.3A) None	0.86A	11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	GLY A 172 VAL A 179 ALA A 192 PHE A 267 ALA A 329	BI9  A 501 (-3.6A) BI9  A 501 ( 4.8A) BI9  A 501 (-3.3A) BI9  A 501 ( 4.2A) NH4  A 506 ( 3.7A)	0.31A	22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	6bx6	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 (Homo sapiens)	5 / 12	LEU A  22 GLY A  23 VAL A  30 ALA A  43 ALA A 156	EDJ  A 301 (-3.9A) EDJ  A 301 (-3.4A) None EDJ  A 301 (-3.4A) EDJ  A 301 (-3.2A)	0.55A	26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	6ccf	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 1 (Homo sapiens)	5 / 12	GLY A 135 VAL A 142 ALA A 155 PHE A 230 ALA A 292	H1N  A 501 ( 3.8A) H1N  A 501 (-4.4A) H1N  A 501 (-3.4A) H1N  A 501 (-3.7A) H1N  A 501 ( 3.9A)	0.30A	22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	6fyl	DUAL SPECIFICITY PROTEIN KINASE CLK2 (Homo sapiens)	6 / 12	LEU A 169 GLY A 170 VAL A 177 ALA A 191 PHE A 243 GLY A 247	3NG  A 501 (-3.9A) 3NG  A 501 (-3.5A) 3NG  A 501 ( 4.4A) 3NG  A 501 (-3.3A) 3NG  A 501 (-3.5A) None	0.62A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	6fyo	DUAL SPECIFICITY PROTEIN KINASE CLK1 (Homo sapiens)	5 / 12	LEU A 167 GLY A 168 VAL A 175 ALA A 189 PHE A 241	EAQ  A 501 (-3.9A) None None EAQ  A 501 (-3.6A) EAQ  A 501 (-3.5A)	0.13A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	6fyo	DUAL SPECIFICITY PROTEIN KINASE CLK1 (Homo sapiens)	5 / 12	LEU A 167 VAL A 175 ALA A 189 PHE A 241 GLY A 245	EAQ  A 501 (-3.9A) None EAQ  A 501 (-3.6A) EAQ  A 501 (-3.5A) EAQ  A 501 (-3.9A)	0.58A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	6fyv	DUAL SPECIFICITY PROTEIN KINASE CLK4 (Homo sapiens)	5 / 12	LEU A 167 GLY A 168 VAL A 175 ALA A 189 PHE A 241	3NG  A 501 (-3.9A) 3NG  A 501 (-3.5A) 3NG  A 501 ( 4.3A) 3NG  A 501 (-3.5A) 3NG  A 501 (-3.5A)	0.34A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_2 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	1r47	ALPHA-GALACTOSIDASE A (Homo sapiens)	4 / 4	VAL A 413 LEU A 414 LEU A 387 ASP A 313	None	1.20A	12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_2 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2fv2	RCD1 REQUIRED FOR CELL DIFFERENTIATION1 HOMOLOG (Homo sapiens)	4 / 4	VAL A 264 LEU A 263 LEU A 221 ASP A 225	None	0.74A	15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_2 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2p1f	URIDINE 5'-MONOPHOSPHATE SYNTHASE (Homo sapiens)	4 / 4	VAL A  50 LEU A  54 LEU A  55 ASP A 256	None	1.34A	13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_2 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	2qcm	URIDINE 5'-MONOPHOSPHATE SYNTHASE (UMP SYNTHASE) (Homo sapiens)	4 / 4	VAL A 239 LEU A 243 LEU A 244 ASP A 445	None	1.35A	13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_2 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	3vu7	DNA REPAIR PROTEIN REV1 (Homo sapiens)	4 / 4	VAL H1239 LEU H1240 LEU H1248 ASP H1207	None	1.42A	22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_2 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	4gk5	DNA REPAIR PROTEIN REV1 (Homo sapiens)	4 / 4	VAL E1239 LEU E1240 LEU E1248 ASP E1207	None	1.48A	20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_2 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5gje	LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6 (Homo sapiens)	4 / 4	VAL A 410 LEU A 398 LEU A 413 ASP A 349	None None PO4  A 708 (-4.5A) None	1.26A	7.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_2 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5gje	LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6 (Homo sapiens)	4 / 4	VAL B 731 LEU B 719 LEU B 734 ASP B 670	None	1.29A	10.06