POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_A_DX4A270_0 (PTERIDINE REDUCTASE 1)	2bov	RAS-RELATED PROTEIN RAL-A (Homo sapiens)	4 / 6	ARG A 113 PHE A  83 ASP A  74 TYR A  82	None	1.46A	20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_A_DX4A270_0 (PTERIDINE REDUCTASE 1)	3a98	DEDICATOR OF CYTOKINESIS PROTEIN 2 ENGULFMENT AND CELL MOTILITY PROTEIN 1 (Homo sapiens; Homo sapiens)	4 / 6	SER A 109 PHE A 114 ASP B 685 TYR A 106	None	1.45A	21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_A_DX4A270_0 (PTERIDINE REDUCTASE 1)	3avs	LYSINE-SPECIFIC DEMETHYLASE 6A (Homo sapiens)	4 / 6	ARG A1142 PHE A1079 ASP A1013 PRO A1007	None	0.96A	21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_A_DX4A270_0 (PTERIDINE REDUCTASE 1)	3e9l	PRE-MRNA-PROCESSING- SPLICING FACTOR 8 (Homo sapiens)	4 / 6	SER A1928 PHE A1772 TYR A1930 PRO A1812	CL  A2018 ( 4.8A) None None None	1.35A	22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_A_DX4A270_0 (PTERIDINE REDUCTASE 1)	3v4o	MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 (Homo sapiens)	4 / 6	ARG A 392 PHE A 424 ASP A 471 TYR A 417	None	1.11A	21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_A_DX4A270_0 (PTERIDINE REDUCTASE 1)	4i1p	MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 (Homo sapiens)	4 / 6	ARG A 392 PHE A 424 ASP A 471 TYR A 417	ACT  A 804 ( 2.9A) None None None	1.01A	19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_A_DX4A270_0 (PTERIDINE REDUCTASE 1)	5fxv	HISTONE DEMETHYLASE UTY (Homo sapiens)	4 / 6	ARG A1089 PHE A1026 ASP A 960 PRO A 954	None	0.96A	20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_A_DX4A270_0 (PTERIDINE REDUCTASE 1)	6eot	DIPEPTIDYL PEPTIDASE 8 (Homo sapiens)	4 / 6	SER A 586 PHE A 584 ASP A 568 TYR A 600	None	1.48A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_B_DX4B270_0 (PTERIDINE REDUCTASE 1)	2bov	RAS-RELATED PROTEIN RAL-A (Homo sapiens)	4 / 6	ARG A 113 PHE A  83 ASP A  74 TYR A  82	None	1.46A	20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_B_DX4B270_0 (PTERIDINE REDUCTASE 1)	2f8a	GLUTATHIONE PEROXIDASE 1 (Homo sapiens)	4 / 6	SER A 135 ASP A 189 TYR A 177 PRO A 173	None	1.46A	24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_B_DX4B270_0 (PTERIDINE REDUCTASE 1)	2v24	SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4 (Homo sapiens)	4 / 6	ARG A 109 SER A 147 PHE A 171 PRO A 174	None	1.25A	23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_B_DX4B270_0 (PTERIDINE REDUCTASE 1)	3a98	DEDICATOR OF CYTOKINESIS PROTEIN 2 ENGULFMENT AND CELL MOTILITY PROTEIN 1 (Homo sapiens; Homo sapiens)	4 / 6	SER A 109 PHE A 114 ASP B 685 TYR A 106	None	1.44A	21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_B_DX4B270_0 (PTERIDINE REDUCTASE 1)	3e9l	PRE-MRNA-PROCESSING- SPLICING FACTOR 8 (Homo sapiens)	4 / 6	SER A1928 PHE A1772 TYR A1930 PRO A1812	CL  A2018 ( 4.8A) None None None	1.37A	22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_B_DX4B270_0 (PTERIDINE REDUCTASE 1)	3v4o	MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 (Homo sapiens)	4 / 6	ARG A 392 PHE A 424 ASP A 471 TYR A 417	None	1.11A	21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_B_DX4B270_0 (PTERIDINE REDUCTASE 1)	4i1p	MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 (Homo sapiens)	4 / 6	ARG A 392 PHE A 424 ASP A 471 TYR A 417	ACT  A 804 ( 2.9A) None None None	1.01A	19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_B_DX4B270_0 (PTERIDINE REDUCTASE 1)	5fxv	HISTONE DEMETHYLASE UTY (Homo sapiens)	4 / 6	ARG A1089 PHE A1026 ASP A 960 PRO A 954	None	1.09A	20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_C_DX4C270_0 (PTERIDINE REDUCTASE 1)	2bov	RAS-RELATED PROTEIN RAL-A (Homo sapiens)	4 / 6	ARG A 113 PHE A  83 ASP A  74 TYR A  82	None	1.48A	20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_C_DX4C270_0 (PTERIDINE REDUCTASE 1)	3a98	DEDICATOR OF CYTOKINESIS PROTEIN 2 ENGULFMENT AND CELL MOTILITY PROTEIN 1 (Homo sapiens; Homo sapiens)	4 / 6	SER A 109 PHE A 114 ASP B 685 TYR A 106	None	1.43A	21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_C_DX4C270_0 (PTERIDINE REDUCTASE 1)	3avs	LYSINE-SPECIFIC DEMETHYLASE 6A (Homo sapiens)	4 / 6	ARG A1142 PHE A1079 ASP A1013 PRO A1007	None	0.96A	21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_C_DX4C270_0 (PTERIDINE REDUCTASE 1)	3d5e	PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE (Homo sapiens)	4 / 6	SER A 150 PHE A 274 ASP A 181 PRO A 301	None	1.41A	19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_C_DX4C270_0 (PTERIDINE REDUCTASE 1)	3e9l	PRE-MRNA-PROCESSING- SPLICING FACTOR 8 (Homo sapiens)	4 / 6	SER A1928 PHE A1772 TYR A1930 PRO A1812	CL  A2018 ( 4.8A) None None None	1.39A	22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_C_DX4C270_0 (PTERIDINE REDUCTASE 1)	3v4o	MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 (Homo sapiens)	4 / 6	ARG A 392 PHE A 424 ASP A 471 TYR A 417	None	1.08A	21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_C_DX4C270_0 (PTERIDINE REDUCTASE 1)	4i1p	MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 (Homo sapiens)	4 / 6	ARG A 392 PHE A 424 ASP A 471 TYR A 417	ACT  A 804 ( 2.9A) None None None	0.98A	19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_C_DX4C270_0 (PTERIDINE REDUCTASE 1)	5fxv	HISTONE DEMETHYLASE UTY (Homo sapiens)	4 / 6	ARG A1089 PHE A1026 ASP A 960 PRO A 954	None	0.96A	20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_D_DX4D270_0 (PTERIDINE REDUCTASE 1)	2bov	RAS-RELATED PROTEIN RAL-A (Homo sapiens)	4 / 6	ARG A 113 PHE A  83 ASP A  74 TYR A  82	None	1.49A	20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_D_DX4D270_0 (PTERIDINE REDUCTASE 1)	3a98	DEDICATOR OF CYTOKINESIS PROTEIN 2 ENGULFMENT AND CELL MOTILITY PROTEIN 1 (Homo sapiens; Homo sapiens)	4 / 6	SER A 109 PHE A 114 ASP B 685 TYR A 106	None	1.44A	21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_D_DX4D270_0 (PTERIDINE REDUCTASE 1)	3avs	LYSINE-SPECIFIC DEMETHYLASE 6A (Homo sapiens)	4 / 6	ARG A1142 PHE A1079 ASP A1013 PRO A1007	None	0.95A	21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_D_DX4D270_0 (PTERIDINE REDUCTASE 1)	3d5e	PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE (Homo sapiens)	4 / 6	SER A 150 PHE A 274 ASP A 181 PRO A 301	None	1.41A	19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_D_DX4D270_0 (PTERIDINE REDUCTASE 1)	3e9l	PRE-MRNA-PROCESSING- SPLICING FACTOR 8 (Homo sapiens)	4 / 6	SER A1928 PHE A1772 TYR A1930 PRO A1812	CL  A2018 ( 4.8A) None None None	1.38A	22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_D_DX4D270_0 (PTERIDINE REDUCTASE 1)	3v4o	MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 (Homo sapiens)	4 / 6	ARG A 392 PHE A 424 ASP A 471 TYR A 417	None	1.06A	21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_D_DX4D270_0 (PTERIDINE REDUCTASE 1)	4i1p	MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 (Homo sapiens)	4 / 6	ARG A 392 PHE A 424 ASP A 471 TYR A 417	ACT  A 804 ( 2.9A) None None None	0.96A	19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_D_DX4D270_0 (PTERIDINE REDUCTASE 1)	5fxv	HISTONE DEMETHYLASE UTY (Homo sapiens)	4 / 6	ARG A1089 PHE A1026 ASP A 960 PRO A 954	None	0.95A	20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	1jy1	TYROSYL-DNA PHOSPHODIESTERASE (Homo sapiens)	4 / 8	GLY A 371 THR A 513 LEU A 542 ARG A 374	None	0.94A	19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	2yx8	RECEPTOR ACTIVITY-MODIFYING PROTEIN 1 (Homo sapiens)	4 / 8	GLY A  33 THR A  73 LEU A  41 PHE A  92	None	1.17A	22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	3n1g	BROTHER OF CDO (Homo sapiens)	4 / 8	GLY C 796 THR C 743 ASN C 794 ARG C 711	None	1.07A	20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	3n7p	RECEPTOR ACTIVITY-MODIFYING PROTEIN 1 (Homo sapiens)	4 / 8	GLY D  33 THR D  73 LEU D  41 PHE D  92	None	1.12A	21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	3nvq	SEMAPHORIN-7A (Homo sapiens)	4 / 8	GLY A  93 THR A 110 ASN A 112 ARG A  92	None	1.24A	14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	3v42	FOLLICULIN (Homo sapiens)	4 / 8	GLY A 371 LEU A 391 ASN A 416 PHE A 417	None	1.23A	25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	4p22	UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 1 (Homo sapiens)	4 / 8	GLY A 105 THR A 148 LEU A 101 ASN A 126	None	1.14A	17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	5ezd	KUNITZ-TYPE PROTEASE INHIBITOR 1 (Homo sapiens)	4 / 8	GLY A 194 LEU A 210 TYR A 218 PHE A 220	None	1.23A	20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	5ikp	GLYCOGEN PHOSPHORYLASE, BRAIN FORM (Homo sapiens)	4 / 8	THR A 237 LEU A 150 ASN A 235 ARG A 489	None	1.10A	12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	5nx2	GLUCAGON-LIKE PEPTIDE 1 RECEPTOR (Homo sapiens)	4 / 8	THR A 149 LEU A 388 TYR A 152 ARG A 190	None	1.01A	17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	5v6y	MALTOSE-BINDING PERIPLASMIC PROTEIN,RECEPTOR ACTIVITY-MODIFYING PROTEIN 1,CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR (Escherichia coli; Homo sapiens)	4 / 8	GLY A1033 THR A1073 LEU A1041 PHE A1092	None	1.21A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	5xjy	ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 1 (Homo sapiens)	4 / 8	THR A 566 LEU A1377 ASN A1633 ARG A 557	None	1.18A	5.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	5yjh	PERIOSTIN (Homo sapiens)	4 / 8	GLY A 264 THR A 353 LEU A 271 ASN A 355	None	1.13A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	1fw1	GLUTATHIONE TRANSFERASE ZETA (Homo sapiens)	4 / 6	ALA A  23 LYS A  27 LEU A 164 MET A 161	None	1.18A	20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	1l1o	REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT (Homo sapiens)	4 / 6	ALA C 536 GLN C 533 LEU C 516 LEU C 547	None	1.14A	19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	1nav	HORMONE RECEPTOR ALPHA 1, THRA1 (Homo sapiens)	4 / 6	ALA A 317 GLN A 320 LEU A 318 LEU A 236	None	1.18A	21.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	1ua2	CELL DIVISION PROTEIN KINASE 7 (Homo sapiens)	4 / 6	ALA A  39 LYS A  41 MET A  94 LEU A 144	ATP  A 381 (-3.6A) ATP  A 381 (-2.9A) None None	0.59A	35.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2ac5	MAP KINASE-INTERACTING SERINE/THREONINE KINASE 2 (Homo sapiens)	4 / 6	ALA A 360 GLN A 361 LEU A 363 LEU A 278	None	1.10A	25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2dyl	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7 (Homo sapiens)	4 / 6	ALA A 163 LEU A 214 MET A 215 LEU A 266	None	0.55A	25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2f37	TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 2 (Homo sapiens)	4 / 6	ALA A 236 GLN A 234 LEU A 213 LEU A 167	None	1.17A	22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2h8r	HEPATOCYTE NUCLEAR FACTOR 1-BETA (Homo sapiens)	4 / 6	ALA A 167 GLN A 163 LEU A 168 LEU A 114	None	1.13A	21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2hw6	MAP KINASE-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 1 (Homo sapiens)	4 / 6	ALA A 325 GLN A 326 LEU A 328 LEU A 243	None	1.10A	25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2p54	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA (Homo sapiens)	4 / 6	ALA A 319 LEU A 433 MET A 430 LEU A 426	None	1.18A	22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2r4b	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	4 / 6	ALA A 749 LEU A 798 MET A 799 LEU A 850	GW7  A   1 (-3.3A) GW7  A   1 (-4.5A) None GW7  A   1 (-4.2A)	0.46A	24.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2wnt	RIBOSOMAL PROTEIN S6 KINASE (Homo sapiens)	4 / 6	ALA A 445 LEU A 491 MET A 492 LEU A 542	None	0.83A	30.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2xk9	CHECKPOINT KINASE 2 (Homo sapiens)	4 / 6	ALA A 247 LEU A 303 MET A 304 LEU A 354	XK9  A1511 ( 4.1A) XK9  A1511 (-4.1A) None XK9  A1511 (-4.6A)	0.24A	31.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2y7j	PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM (Homo sapiens)	4 / 6	ALA A  51 LEU A 109 MET A 110 LEU A 160	B49  A1294 (-3.2A) B49  A1294 ( 4.7A) None B49  A1294 (-4.4A)	0.18A	23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3c49	POLY(ADP-RIBOSE) POLYMERASE 3 (Homo sapiens)	4 / 6	ALA A 281 GLN A 280 LEU A 278 LEU A 233	None	1.12A	22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3d5f	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA (Homo sapiens)	4 / 6	ALA A 328 LEU A 442 MET A 439 LEU A 435	None	1.14A	20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3fme	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 (Homo sapiens)	4 / 6	ALA A  80 LEU A 131 MET A 132 LEU A 186	STU  A   1 (-3.4A) STU  A   1 (-4.6A) None STU  A   1 (-4.4A)	0.20A	26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3i6u	SERINE/THREONINE-PRO TEIN KINASE CHK2 (Homo sapiens)	4 / 6	ALA A 247 LEU A 303 MET A 304 LEU A 354	None	0.56A	26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3ifq	PLAKOGLOBIN (Homo sapiens)	4 / 6	ALA A 314 GLN A 317 LEU A 315 LEU A 285	None	1.09A	23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3lzb	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	4 / 6	ALA A 719 LEU A 768 MET A 769 LEU A 820	ITI  A   1 (-2.9A) ITI  A   1 (-4.8A) ITI  A   1 (-4.8A) ITI  A   1 (-4.6A)	0.88A	22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	4 / 6	ALA A 213 LEU A 265 MET A 266 LEU A 318	AMP  A 577 (-3.4A) AMP  A 577 ( 4.9A) None AMP  A 577 (-4.8A)	0.38A	21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	4 / 6	ALA A 751 LEU A 800 MET A 801 LEU A 852	03Q  A   1 (-3.1A) 03Q  A   1 (-4.6A) None 03Q  A   1 (-4.4A)	0.43A	24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3swv	BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 2 (Homo sapiens)	4 / 6	ALA A 679 GLN A 680 LEU A 682 LEU A 671	None	1.11A	24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3vn9	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 (Homo sapiens)	4 / 6	ALA A  80 LEU A 131 MET A 132 LEU A 186	ANK  A 401 (-3.0A) None None ANK  A 401 ( 4.9A)	0.44A	25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	4 / 6	ALA A1978 LEU A2028 MET A2029 LEU A2086	VGH  A3000 (-3.4A) VGH  A3000 ( 4.8A) None VGH  A3000 (-4.3A)	0.22A	27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3zgq	INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5 (Homo sapiens)	4 / 6	ALA A  77 GLN A  76 LEU A  51 LEU A  42	None	1.20A	20.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4b99	MITOGEN-ACTIVATED PROTEIN KINASE 7 (Homo sapiens)	4 / 6	ALA A  82 LEU A 139 MET A 140 LEU A 189	R4L  A1394 ( 3.7A) R4L  A1394 ( 4.9A) None R4L  A1394 (-4.5A)	0.46A	46.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4cql	ESTRADIOL 17-BETA-DEHYDROGENAS E 8 (Homo sapiens)	4 / 6	ALA A 139 GLN A 140 LEU A 142 LEU A  86	None	1.09A	21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	4 / 6	ALA A1148 LEU A1198 MET A1199 LEU A1256	0UV  A1501 (-3.4A) 0UV  A1501 ( 4.8A) None 0UV  A1501 (-4.6A)	0.24A	24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4mk0	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	4 / 6	ALA A 218 LEU A 273 MET A 274 LEU A 324	29X  A 702 (-3.1A) 29X  A 702 (-4.6A) None 29X  A 702 (-4.6A)	0.42A	21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4mxw	LYMPHOTOXIN-BETA (Homo sapiens)	4 / 6	ALA Y 126 GLN Y 118 LEU Y 127 LEU Y 113	None	0.97A	18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4p2k	EPHRIN TYPE-A RECEPTOR 2 (Homo sapiens)	4 / 6	ALA A 644 LYS A 646 MET A 695 LEU A 746	None	0.81A	26.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4qtb	MITOGEN-ACTIVATED PROTEIN KINASE 3 (Homo sapiens)	5 / 6	ALA A  69 GLN A 122 LEU A 124 MET A 125 LEU A 173	38Z  A 418 (-3.4A) 38Z  A 418 (-3.7A) 38Z  A 418 ( 4.8A) None 38Z  A 418 (-4.4A)	0.21A	85.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4zsl	MITOGEN-ACTIVATED PROTEIN KINASE 7 (Homo sapiens)	4 / 6	ALA A  82 LEU A 139 MET A 140 LEU A 189	None	0.40A	48.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	5j9z	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	4 / 6	ALA A 743 LEU A 792 MET A 793 LEU A 844	6HJ  A1101 (-3.1A) 6HJ  A1101 ( 4.9A) None 6HJ  A1101 ( 4.8A)	0.21A	25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	5uuu	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	4 / 6	ALA A 218 LEU A 273 MET A 274 LEU A 324	QRW  A 601 (-3.4A) None MES  A 604 (-3.9A) None	0.41A	22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XOY_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	6cz4	PROTEIN-TYROSINE KINASE 6 (Homo sapiens)	4 / 6	ALA A 217 LEU A 266 MET A 267 LEU A 319	FKY  A9001 (-3.3A) FKY  A9001 (-4.4A) None FKY  A9001 ( 4.9A)	0.36A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	1fw1	GLUTATHIONE TRANSFERASE ZETA (Homo sapiens)	4 / 6	ALA A  23 LYS A  27 LEU A 164 MET A 161	None	1.18A	20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	1l1o	REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT (Homo sapiens)	4 / 6	ALA C 536 GLN C 533 LEU C 516 LEU C 547	None	1.20A	19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2dkl	TRINUCLEOTIDE REPEAT CONTAINING 6C PROTEIN (Homo sapiens)	4 / 6	ALA A  38 LEU A  56 MET A  53 LEU A  49	None	1.20A	11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2dyl	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7 (Homo sapiens)	4 / 6	ALA A 163 LEU A 214 MET A 215 LEU A 266	None	0.66A	25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2f37	TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 2 (Homo sapiens)	4 / 6	ALA A 236 GLN A 234 LEU A 213 LEU A 167	None	1.22A	22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2mc3	MUS81 ENDONUCLEASE HOMOLOG (YEAST), ISOFORM CRA_B (Homo sapiens)	4 / 6	ALA A  90 GLN A  87 LEU A  16 LEU A  23	None	1.20A	15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2p54	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA (Homo sapiens)	4 / 6	ALA A 319 LEU A 433 MET A 430 LEU A 426	None	1.18A	22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2pop	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7-INTERACTING PROTEIN 1 (Homo sapiens)	4 / 6	ALA A 188 GLN A 202 LEU A 287 MET A 288	None	1.26A	20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2qs9	RETINOBLASTOMA-BINDI NG PROTEIN 9 (Homo sapiens)	4 / 6	ALA A  98 GLN A 146 LEU A  95 LEU A 157	None	1.24A	18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2r2w	PLASMINOGEN ACTIVATOR, UROKINASE (Homo sapiens)	4 / 6	ALA U 112 GLN U 113 LEU U  68 MET U  81	None	1.27A	19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2r4b	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	4 / 6	ALA A 749 LEU A 798 MET A 799 LEU A 850	GW7  A   1 (-3.3A) GW7  A   1 (-4.5A) None GW7  A   1 (-4.2A)	0.50A	24.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2wnt	RIBOSOMAL PROTEIN S6 KINASE (Homo sapiens)	4 / 6	ALA A 445 LEU A 491 MET A 492 LEU A 542	None	0.90A	30.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2xk9	CHECKPOINT KINASE 2 (Homo sapiens)	4 / 6	ALA A 247 LEU A 303 MET A 304 LEU A 354	XK9  A1511 ( 4.1A) XK9  A1511 (-4.1A) None XK9  A1511 (-4.6A)	0.19A	31.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2xsx	BETA-ENOLASE (Homo sapiens)	4 / 6	ALA A 123 LYS A 126 LEU A 130 LEU A 137	None	1.22A	21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2y7j	PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM (Homo sapiens)	4 / 6	ALA A  51 LEU A 109 MET A 110 LEU A 160	B49  A1294 (-3.2A) B49  A1294 ( 4.7A) None B49  A1294 (-4.4A)	0.25A	23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3d5f	PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA (Homo sapiens)	4 / 6	ALA A 328 LEU A 442 MET A 439 LEU A 435	None	1.14A	20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3fme	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 (Homo sapiens)	4 / 6	ALA A  80 LEU A 131 MET A 132 LEU A 186	STU  A   1 (-3.4A) STU  A   1 (-4.6A) None STU  A   1 (-4.4A)	0.30A	26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3i6u	SERINE/THREONINE-PRO TEIN KINASE CHK2 (Homo sapiens)	4 / 6	ALA A 247 LEU A 303 MET A 304 LEU A 354	None	0.69A	26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3lzb	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	4 / 6	ALA A 719 LEU A 768 MET A 769 LEU A 820	ITI  A   1 (-2.9A) ITI  A   1 (-4.8A) ITI  A   1 (-4.8A) ITI  A   1 (-4.6A)	0.81A	22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	4 / 6	ALA A 213 LEU A 265 MET A 266 LEU A 318	AMP  A 577 (-3.4A) AMP  A 577 ( 4.9A) None AMP  A 577 (-4.8A)	0.39A	21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	4 / 6	ALA A 751 LEU A 800 MET A 801 LEU A 852	03Q  A   1 (-3.1A) 03Q  A   1 (-4.6A) None 03Q  A   1 (-4.4A)	0.44A	24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3swv	BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 2 (Homo sapiens)	4 / 6	ALA A 679 GLN A 680 LEU A 682 LEU A 671	None	1.22A	24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3vn9	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 (Homo sapiens)	4 / 6	ALA A  80 LEU A 131 MET A 132 LEU A 186	ANK  A 401 (-3.0A) None None ANK  A 401 ( 4.9A)	0.41A	25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	4 / 6	ALA A1978 LEU A2028 MET A2029 LEU A2086	VGH  A3000 (-3.4A) VGH  A3000 ( 4.8A) None VGH  A3000 (-4.3A)	0.29A	27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	3zgq	INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5 (Homo sapiens)	4 / 6	ALA A  77 GLN A  76 LEU A  51 LEU A  42	None	1.18A	20.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4b99	MITOGEN-ACTIVATED PROTEIN KINASE 7 (Homo sapiens)	4 / 6	ALA A  82 LEU A 139 MET A 140 LEU A 189	R4L  A1394 ( 3.7A) R4L  A1394 ( 4.9A) None R4L  A1394 (-4.5A)	0.54A	46.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	4 / 6	ALA A1148 LEU A1198 MET A1199 LEU A1256	0UV  A1501 (-3.4A) 0UV  A1501 ( 4.8A) None 0UV  A1501 (-4.6A)	0.21A	24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4mk0	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	4 / 6	ALA A 218 LEU A 273 MET A 274 LEU A 324	29X  A 702 (-3.1A) 29X  A 702 (-4.6A) None 29X  A 702 (-4.6A)	0.42A	21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4mxw	LYMPHOTOXIN-BETA (Homo sapiens)	4 / 6	ALA Y 126 GLN Y 118 LEU Y 127 LEU Y 113	None	0.93A	18.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4qtb	MITOGEN-ACTIVATED PROTEIN KINASE 3 (Homo sapiens)	5 / 6	ALA A  69 GLN A 122 LEU A 124 MET A 125 LEU A 173	38Z  A 418 (-3.4A) 38Z  A 418 (-3.7A) 38Z  A 418 ( 4.8A) None 38Z  A 418 (-4.4A)	0.32A	85.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4xii	CHOLINESTERASE (Homo sapiens)	4 / 6	ALA A  34 GLN A  35 LEU A  93 LEU A  41	None	0.99A	21.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	4zsl	MITOGEN-ACTIVATED PROTEIN KINASE 7 (Homo sapiens)	4 / 6	ALA A  82 LEU A 139 MET A 140 LEU A 189	None	0.42A	48.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	5i8g	CREB-BINDING PROTEIN (Homo sapiens)	4 / 6	ALA A1093 GLN A1092 LEU A1094 MET A1095	None None None PEG  A1413 ( 4.2A)	1.27A	23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	5j9z	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	4 / 6	ALA A 743 LEU A 792 MET A 793 LEU A 844	6HJ  A1101 (-3.1A) 6HJ  A1101 ( 4.9A) None 6HJ  A1101 ( 4.8A)	0.24A	25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	5uuu	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	4 / 6	ALA A 218 LEU A 273 MET A 274 LEU A 324	QRW  A 601 (-3.4A) None MES  A 604 (-3.9A) None	0.39A	22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP3_A_DX4A401_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	6cz4	PROTEIN-TYROSINE KINASE 6 (Homo sapiens)	4 / 6	ALA A 217 LEU A 266 MET A 267 LEU A 319	FKY  A9001 (-3.3A) FKY  A9001 (-4.4A) None FKY  A9001 ( 4.9A)	0.31A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	2ayn	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 (Homo sapiens)	4 / 8	GLY A 105 LEU A 106 ASN A 116 PHE A 449	None	0.43A	26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	2ayn	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 (Homo sapiens)	4 / 8	GLY A 105 LEU A 106 GLN A 120 PHE A 449	None	0.70A	26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	2f1z	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 (Homo sapiens)	5 / 8	GLY A 215 LEU A 216 ASN A 226 GLN A 230 PHE A 480	None	0.59A	23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	2f1z	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 (Homo sapiens)	4 / 8	GLY A 215 SER A 227 GLN A 230 PHE A 480	None	0.64A	23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	2q9g	CYTOCHROME P450 46A1 (Homo sapiens)	4 / 8	GLY A 124 LEU A 125 GLN A 137 ALA A 282	None HEM  A 505 (-4.1A) None None	0.86A	22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	2vc2	INTEGRIN ALPHA-IIB (Homo sapiens)	4 / 8	GLY A  44 LEU A  43 SER A  17 ALA A  39	None	0.96A	20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	2y6e	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4 (Homo sapiens)	7 / 8	GLY A 303 LEU A 304 ASN A 314 SER A 315 GLN A 318 ALA A 884 PHE A 897	None None CME  A 311 ( 4.7A) CME  A 311 ( 4.7A) None None None	0.27A	41.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	3i3t	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21 (Homo sapiens)	5 / 8	GLY A 213 LEU A 214 ASN A 224 GLN A 228 ALA A 521	None	0.27A	49.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	3lpp	SUCRASE-ISOMALTASE (Homo sapiens)	4 / 8	GLY A 849 ASN A 878 SER A 877 GLN A 879	None	0.93A	16.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	3n3k	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 8 (Homo sapiens)	7 / 8	GLY A 778 LEU A 779 ASN A 789 SER A 790 GLN A 793 ALA A1070 PHE A1083	None	0.34A	38.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	3nhe	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2 (Homo sapiens)	7 / 8	GLY A 268 LEU A 269 ASN A 279 SER A 280 GLN A 283 ALA A 560 PHE A 573	None None CME  A 276 ( 4.0A) CME  A 276 ( 4.5A) None None None	0.10A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	3t2n	SERINE PROTEASE HEPSIN (Homo sapiens)	4 / 8	GLY A  94 LEU A 278 CYH A 372 SER A 394	None	0.76A	21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	4zyo	ACYL-COA DESATURASE (Homo sapiens)	4 / 8	GLY A  89 LEU A  92 ASN A 244 SER A 245	None	0.87A	21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	4zyo	ACYL-COA DESATURASE (Homo sapiens)	4 / 8	LEU A  92 ASN A 244 SER A 245 ALA A 249	None	0.98A	21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5crv	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23 (Homo sapiens)	4 / 8	LEU A 180 GLN A 184 ALA A 185 PHE A 147	None	0.98A	21.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5cvo	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 46 (Homo sapiens)	6 / 8	GLY B  36 LEU B  37 ASN B  47 SER B  48 GLN B  51 PHE B 327	None	0.64A	30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5gjq	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 (Homo sapiens)	5 / 8	GLY x 105 LEU x 106 ASN x 116 GLN x 120 PHE x 449	None	0.86A	23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5j7t	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 (Homo sapiens)	5 / 8	GLY A 215 LEU A 216 ASN A 226 GLN A 230 PHE A 480	None	0.36A	20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5j7t	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 (Homo sapiens)	5 / 8	GLY A 215 LEU A 216 SER A 227 GLN A 230 PHE A 480	None	0.62A	20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5jtv	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 (Homo sapiens)	5 / 8	GLY A 215 LEU A 216 ASN A 226 GLN A 230 PHE A 480	None	0.29A	21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5jtv	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 (Homo sapiens)	4 / 8	LEU A 216 SER A 227 GLN A 230 PHE A 480	None	0.63A	21.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5k1c	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12 (Homo sapiens)	4 / 8	GLY A  40 LEU A  41 ASN A  51 ALA A 320	None	0.35A	30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5k1c	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12 (Homo sapiens)	4 / 8	GLY A  40 LEU A  41 SER A  52 ALA A 320	None	0.73A	30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5k1c	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12 (Homo sapiens)	4 / 8	LEU A  41 ASN A  51 ALA A 320 PHE A 331	None	0.52A	30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5k1c	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12 (Homo sapiens)	4 / 8	LEU A  41 SER A  52 ALA A 320 PHE A 331	None	0.81A	30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5lxg	ADIPONECTIN RECEPTOR PROTEIN 1 (Homo sapiens)	4 / 8	GLY A 275 LEU A 276 ALA A 268 PHE A 271	None	0.82A	21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5nge	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 (Homo sapiens)	5 / 8	GLY A 215 LEU A 216 ASN A 226 GLN A 230 PHE A 480	None	0.33A	28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5nge	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 (Homo sapiens)	4 / 8	GLY A 215 SER A 227 GLN A 230 PHE A 480	None	0.64A	28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5o71	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 25 (Homo sapiens)	4 / 8	GLY A 170 LEU A 171 GLN A 185 ALA A 610	None	0.52A	undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5ohk	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30,UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30,UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30 (Homo sapiens)	4 / 8	GLY A  69 LEU A  70 ASN A  80 GLN A  84	None	0.26A	31.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5ohk	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30,UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30,UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30 (Homo sapiens)	4 / 8	GLY A  69 LEU A  70 SER A  81 GLN A  84	None	0.66A	31.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5txk	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 35,UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 35 (Homo sapiens)	5 / 8	GLY A 442 LEU A 443 ASN A 453 GLN A 457 PHE A 893	None	0.35A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5txk	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 35,UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 35 (Homo sapiens)	5 / 8	GLY A 442 LEU A 443 SER A 454 GLN A 457 PHE A 893	None	0.68A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	5wch	PROBABLE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE FAF-X (Homo sapiens)	6 / 8	GLY A1558 LEU A1559 ASN A1569 SER A1570 GLN A1573 PHE A1900	None	0.72A	undetectable