POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	1hjv	CHITINASE-3 LIKE PROTEIN 1 (Homo sapiens)	5 / 12	TYR A  27 VAL A  25 ALA A 138 SER A  95 SER A 175	NAG  A  -1 (-3.8A) None NAG  A  -1 ( 3.9A) None None	1.36A	19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	1hlg	LIPASE, GASTRIC (Homo sapiens)	5 / 12	VAL A 366 ILE A 370 PHE A 176 PHE A 160 ALA A 327	None	1.20A	17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	1lpb	LIPASE (Homo sapiens)	5 / 12	PHE B 386 TYR B 340 VAL B 342 ILE B 420 SER B 388	None	1.05A	17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	1p9o	PHOSPHOPANTOTHENOYLC YSTEINE SYNTHETASE (Homo sapiens)	5 / 12	TYR A 176 VAL A 256 ILE A 269 ALA A  72 SER A  69	None	1.36A	20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	2xa7	AP-2 COMPLEX SUBUNIT BETA (Homo sapiens)	5 / 12	VAL B 310 ILE B 306 PHE B 369 GLU B 337 ALA B 376	None	1.32A	14.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	3apu	ALPHA-1-ACID GLYCOPROTEIN 2 (Homo sapiens)	12 / 12	TYR A  27 PHE A  32 TYR A  37 VAL A  41 ILE A  44 PHE A  49 PHE A  51 GLU A  64 ALA A  99 SER A 114 SER A 125 TYR A 127	PG4  A 190 ( 3.8A) None None PG4  A 190 (-4.9A) None PG4  A 190 ( 4.1A) None PG4  A 190 (-4.1A) PG4  A 190 ( 4.2A) None PG4  A 190 ( 3.7A) None	0.50A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	3kq0	ALPHA-1-ACID GLYCOPROTEIN 1 (Homo sapiens)	10 / 12	TYR A  27 PHE A  32 VAL A  41 ILE A  44 PHE A  49 PHE A  51 GLU A  64 ALA A  99 SER A 125 TYR A 127	None None None None JIM  A 193 (-3.8A) None None JIM  A 193 ( 4.0A) None None	0.73A	86.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	4bpc	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S (Homo sapiens)	5 / 12	PHE A1859 TYR A1818 VAL A1863 ILE A1775 PHE A1823	None	1.40A	17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	4pj3	INTRON-BINDING PROTEIN AQUARIUS (Homo sapiens)	5 / 12	PHE A 123 VAL A 166 ILE A 170 PHE A 253 ALA A 130	None	1.34A	8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	5l7k	PROTEIN UNC-119 HOMOLOG A (Homo sapiens)	5 / 12	ILE A 105 PHE A 133 PHE A 137 SER A 218 TYR A 131	None	1.47A	23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	5nfb	GALECTIN-3 (Homo sapiens)	5 / 12	PHE A 157 VAL A 211 PHE A 190 PHE A 163 ALA A 146	None	1.50A	20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	5vzt	F-BOX ONLY PROTEIN 31 (Homo sapiens)	5 / 12	TYR B 509 VAL B 344 PHE B 491 PHE B 446 SER B 507	None None None None DTT  B 602 ( 4.9A)	1.44A	17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_2 (ALPHA-1-ACID GLYCOPROTEIN 2)	1qg1	PROTEIN (GROWTH FACTOR RECEPTOR BINDING PROTEIN) (Homo sapiens)	4 / 4	VAL E  44 ARG E  94 HIS E  24 PHE E  46	None	1.19A	18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_2 (ALPHA-1-ACID GLYCOPROTEIN 2)	1wgr	GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7 (Homo sapiens)	4 / 4	VAL A  40 ARG A  33 HIS A  34 PHE A  89	None	1.15A	17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_2 (ALPHA-1-ACID GLYCOPROTEIN 2)	2p57	GTPASE-ACTIVATING PROTEIN ZNF289 (Homo sapiens)	4 / 4	VAL A  58 ARG A  54 HIS A  53 PHE A  62	None	1.49A	23.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3APW_A_DP0A190_2 (ALPHA-1-ACID GLYCOPROTEIN 2)	3apu	ALPHA-1-ACID GLYCOPROTEIN 2 (Homo sapiens)	4 / 4	VAL A  88 ARG A  90 HIS A  97 PHE A 112	None PG4  A 190 (-4.3A) None PG4  A 190 ( 3.9A)	0.28A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_2 (ALPHA-1-ACID GLYCOPROTEIN 2)	4n78	CYTOPLASMIC FMR1-INTERACTING PROTEIN 1 (Homo sapiens)	4 / 4	VAL A 480 ARG A 477 HIS A 474 PHE A 391	None	1.30A	9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_2 (ALPHA-1-ACID GLYCOPROTEIN 2)	4ykn	PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA,PHOSPHATIDYLIN OSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM FUSION PROTEIN (Homo sapiens)	4 / 4	VAL A1706 ARG A1704 HIS A1701 PHE A1119	None	1.42A	8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	1h4l	CELL DIVISION PROTEIN KINASE 5 (Homo sapiens)	5 / 12	PHE A  80 LEU A  66 ALA A 148 SER A  47 TYR A  15	None	1.44A	21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	1hlg	LIPASE, GASTRIC (Homo sapiens)	5 / 12	VAL A 366 ILE A 370 PHE A 176 PHE A 160 ALA A 327	None	1.19A	17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	1pk6	COMPLEMENT C1Q SUBCOMPONENT, A CHAIN PRECURSOR COMPLEMENT C1Q SUBCOMPONENT, C CHAIN PRECURSOR (Homo sapiens)	5 / 12	PHE C 212 LEU C 214 GLN C  91 ALA A  94 PHE A 217	None	1.37A	16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	1rxt	GLYCYLPEPTIDE N-TETRADECANOYLTRANS FERASE 1 (Homo sapiens)	5 / 12	PHE A 407 PHE A 413 LEU A 411 ALA A 388 PHE A 396	None	1.45A	17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	1skx	ORPHAN NUCLEAR RECEPTOR PXR (Homo sapiens)	5 / 12	PHE A 369 LEU A 342 ALA A 157 SER A 262 TYR A 263	None	1.38A	19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	2f5a	PROTEIN (ANTIBODY 2F5 (HEAVY CHAIN)) (Homo sapiens)	5 / 12	VAL H  12 ILE H 130 LEU H  65 ARG H  68 TYR H  95	None	1.44A	17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	3a6p	EXPORTIN-5 (Homo sapiens)	5 / 12	VAL A 725 ILE A 728 PHE A 862 ALA A 876 PHE A 895	None	1.39A	9.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	3apu	ALPHA-1-ACID GLYCOPROTEIN 2 (Homo sapiens)	12 / 12	VAL A  41 ILE A  44 PHE A  49 PHE A  51 LEU A  62 GLU A  64 GLN A  66 ARG A  90 ALA A  99 PHE A 112 SER A 125 TYR A 127	PG4  A 190 (-4.9A) None PG4  A 190 ( 4.1A) None None PG4  A 190 (-4.1A) None PG4  A 190 (-4.3A) PG4  A 190 ( 4.2A) PG4  A 190 ( 3.9A) PG4  A 190 ( 3.7A) None	0.66A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	3ctt	MALTASE-GLUCOAMYLASE (Homo sapiens)	5 / 12	GLU A 658 ARG A 730 ALA A 757 PHE A 735 TYR A 636	None	1.45A	12.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	3kq0	ALPHA-1-ACID GLYCOPROTEIN 1 (Homo sapiens)	9 / 12	VAL A  41 ILE A  44 PHE A  49 PHE A  51 LEU A  62 GLN A  66 ARG A  90 SER A 125 TYR A 127	None None JIM  A 193 (-3.8A) None None None JIM  A 193 (-4.3A) None None	0.74A	86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	3kq0	ALPHA-1-ACID GLYCOPROTEIN 1 (Homo sapiens)	10 / 12	VAL A  41 ILE A  44 PHE A  49 PHE A  51 LEU A  62 GLU A  64 ARG A  90 ALA A  99 SER A 125 TYR A 127	None None JIM  A 193 (-3.8A) None None None JIM  A 193 (-4.3A) JIM  A 193 ( 4.0A) None None	0.64A	86.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	4is8	NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 (Homo sapiens)	5 / 12	VAL A 318 ILE A 322 LEU A 531 GLN A 351 ALA A 360	None	1.14A	20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	4xq7	2'-5'-OLIGOADENYLATE SYNTHASE-LIKE PROTEIN (Homo sapiens)	5 / 12	PHE A 191 ALA A 180 PHE A  94 SER A  93 TYR A 157	CME  A 188 ( 4.4A) None CME  A 188 ( 3.6A) None None	1.33A	19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	5hkj	COMPLEMENT C1Q SUBCOMPONENT SUBUNIT A,COMPLEMENT C1Q SUBCOMPONENT SUBUNIT C,COMPLEMENT C1Q SUBCOMPONENT SUBUNIT B (Homo sapiens)	5 / 12	PHE A 265 LEU A 267 GLN A 144 ALA A   7 PHE A 130	None	1.31A	15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	6ez8	HUNTINGTIN (Homo sapiens)	5 / 12	VAL A 746 ILE A 749 PHE A 380 LEU A 376 SER A 725	None	1.36A	13.66