POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2TOD_A_DMOA700_1 (PROTEIN (ORNITHINE DECARBOXYLASE))	1qmv	PEROXIREDOXIN-2 (Homo sapiens)	4 / 6	ASP A 106 PHE A  42 ASP A 114 TYR A 115	None	1.28A	18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2TOD_B_DMOB700_1 (PROTEIN (ORNITHINE DECARBOXYLASE))	1qmv	PEROXIREDOXIN-2 (Homo sapiens)	4 / 5	ASP A 114 TYR A 115 ASP A 106 PHE A  42	None	1.31A	18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2TOD_B_DMOB700_1 (PROTEIN (ORNITHINE DECARBOXYLASE))	5v07	EXONUCLEASE 1 (Homo sapiens)	4 / 5	ASP Z 225 TYR Z 226 ASP Z 152 PHE Z 177	None None MN  Z 401 ( 2.8A) None	1.44A	23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2TOD_B_DMOB700_1 (PROTEIN (ORNITHINE DECARBOXYLASE))	6c0t	CGMP-DEPENDENT PROTEIN KINASE 1 (Homo sapiens)	4 / 5	ASP A 493 TYR A 497 ASP A 419 PHE A 420	None	1.29A	11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2TOD_C_DMOC700_1 (PROTEIN (ORNITHINE DECARBOXYLASE))	1qmv	PEROXIREDOXIN-2 (Homo sapiens)	4 / 5	ASP A 106 PHE A  42 ASP A 114 TYR A 115	None	1.31A	18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2TOD_D_DMOD700_1 (PROTEIN (ORNITHINE DECARBOXYLASE))	1qmv	PEROXIREDOXIN-2 (Homo sapiens)	4 / 5	ASP A 114 TYR A 115 ASP A 106 PHE A  42	None	1.30A	18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GN0_A_DMOA551_1 (ARGINASE-1)	3u78	LYSINE-SPECIFIC DEMETHYLASE 7 (Homo sapiens)	5 / 9	HIS A 282 ASP A 284 SER A 227 ASP A 392 THR A 279	NI  A 702 ( 3.4A) NI  A 702 (-2.6A) None E67  A 707 (-3.4A) AKG  A 701 (-3.6A)	1.47A	22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GN0_A_DMOA551_1 (ARGINASE-1)	3zyi	LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4 (Homo sapiens)	5 / 9	HIS A  97 ASN A 120 HIS A  99 GLY A 121 ASP A  93	None	1.45A	21.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GN0_A_DMOA551_1 (ARGINASE-1)	4hxq	ARGINASE-1 (Homo sapiens)	9 / 9	HIS A 126 ASP A 128 ASN A 130 SER A 137 HIS A 141 GLY A 142 ASP A 183 GLU A 186 THR A 246	MN  A 902 ( 3.4A) MN  A 903 ( 2.6A) X8A  A 901 (-4.4A) X8A  A 901 (-2.5A) X8A  A 901 (-3.4A) X8A  A 901 ( 3.7A) X8A  A 901 (-3.0A) X8A  A 901 ( 4.3A) X8A  A 901 (-3.5A)	0.21A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GN0_A_DMOA551_1 (ARGINASE-1)	4ixu	ARGINASE-2, MITOCHONDRIAL (Homo sapiens)	5 / 9	HIS A 145 ASN A 149 SER A 155 ASP A 202 GLU A 205	MN  A 402 ( 3.3A) 38I  A 406 (-4.2A) 38I  A 406 ( 3.7A) 38I  A 406 (-3.1A) 38I  A 406 ( 4.0A)	1.25A	60.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GN0_A_DMOA551_1 (ARGINASE-1)	4ixu	ARGINASE-2, MITOCHONDRIAL (Homo sapiens)	9 / 9	HIS A 145 ASP A 147 ASN A 149 SER A 156 HIS A 160 GLY A 161 ASP A 202 GLU A 205 THR A 265	MN  A 402 ( 3.3A) 38I  A 406 ( 2.5A) 38I  A 406 (-4.2A) 38I  A 406 (-2.7A) 38I  A 406 (-3.5A) 38I  A 406 ( 3.7A) 38I  A 406 (-3.1A) 38I  A 406 ( 4.0A) 38I  A 406 (-3.7A)	0.27A	60.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GN0_B_DMOB552_1 (ARGINASE-1)	3zyi	LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4 (Homo sapiens)	5 / 9	HIS A  97 ASN A 120 HIS A  99 GLY A 121 ASP A  93	None	1.50A	21.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GN0_B_DMOB552_1 (ARGINASE-1)	4hxq	ARGINASE-1 (Homo sapiens)	9 / 9	HIS A 126 ASP A 128 ASN A 130 SER A 137 HIS A 141 GLY A 142 ASP A 183 GLU A 186 THR A 246	MN  A 902 ( 3.4A) MN  A 903 ( 2.6A) X8A  A 901 (-4.4A) X8A  A 901 (-2.5A) X8A  A 901 (-3.4A) X8A  A 901 ( 3.7A) X8A  A 901 (-3.0A) X8A  A 901 ( 4.3A) X8A  A 901 (-3.5A)	0.19A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GN0_B_DMOB552_1 (ARGINASE-1)	4ixu	ARGINASE-2, MITOCHONDRIAL (Homo sapiens)	5 / 9	HIS A 145 ASN A 149 SER A 155 ASP A 202 GLU A 205	MN  A 402 ( 3.3A) 38I  A 406 (-4.2A) 38I  A 406 ( 3.7A) 38I  A 406 (-3.1A) 38I  A 406 ( 4.0A)	1.21A	60.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GN0_B_DMOB552_1 (ARGINASE-1)	4ixu	ARGINASE-2, MITOCHONDRIAL (Homo sapiens)	9 / 9	HIS A 145 ASP A 147 ASN A 149 SER A 156 HIS A 160 GLY A 161 ASP A 202 GLU A 205 THR A 265	MN  A 402 ( 3.3A) 38I  A 406 ( 2.5A) 38I  A 406 (-4.2A) 38I  A 406 (-2.7A) 38I  A 406 (-3.5A) 38I  A 406 ( 3.7A) 38I  A 406 (-3.1A) 38I  A 406 ( 4.0A) 38I  A 406 (-3.7A)	0.26A	60.58