POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	1gzk	RAC-BETA SERINE/THREONINE PROTEIN KINASE (Homo sapiens)	3 / 3	PHE A 426 TYR A 438 PRO A 428	None	0.77A	20.44 3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	1l6j	MATRIX METALLOPROTEINASE-9 (Homo sapiens)	3 / 3	PHE A 107 TYR A  52 PRO A 102	None	1.15A	18.97 1.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	2kms	COMPLEMENT FACTOR H (Homo sapiens)	3 / 3	PHE A 717 TYR A 709 PRO A 695	None	1.09A	16.67 10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	3 / 3	PHE A 465 TYR A 473 PRO A 467	None	1.14A	16.17 0.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	3sag	EXOSOME COMPONENT 10 (Homo sapiens)	3 / 3	PHE A 198 TYR A 382 PRO A 200	PHE  A 198 ( 1.3A) TYR  A 382 ( 1.3A) PRO  A 200 ( 1.1A)	1.15A	17.45 2.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	3soa	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA WITH A BETA 7 LINKER (Homo sapiens)	3 / 3	PHE A 293 TYR A 179 PRO A 211	None	1.18A	16.44 0.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	3x1o	ROQUIN-1 (Homo sapiens)	3 / 3	PHE A 194 TYR A 308 PRO A 197	None	1.18A	23.01 0.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	4gwn	MEPRIN A SUBUNIT BETA (Homo sapiens)	3 / 3	PHE A 545 TYR A 454 PRO A 452	NAG  A 713 (-3.5A) MAN  A 717 (-3.9A) NAG  A 713 (-4.6A)	1.13A	17.59 12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	4rwf	MALTOSE TRANSPORTER SUBUNIT, RECEPTOR ACTIVITY-MODIFYING PROTEIN 2, CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR FUSION PROTEIN (Escherichia coli; Homo sapiens)	3 / 3	PHE A1111 TYR A2049 PRO A1112	None	1.17A	16.70 4.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	4wrm	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR (Homo sapiens)	3 / 3	PHE A 156 TYR A 100 PRO A 158	None	1.00A	20.66 0.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	4z2a	FURIN (Homo sapiens)	3 / 3	PHE A 118 TYR A 110 PRO A 113	None	0.95A	19.65 3.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	5dsy	POLY [ADP-RIBOSE] POLYMERASE 2 (Homo sapiens)	3 / 3	PHE A 515 TYR A 546 PRO A 524	None	1.17A	21.28 9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	5e1b	N-TERMINAL XAA-PRO-LYS N-METHYLTRANSFERASE 1 (Homo sapiens)	3 / 3	PHE A 122 TYR A 129 PRO A 124	None	0.71A	18.04 11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	5m7r	PROTEIN O-GLCNACASE (Homo sapiens)	3 / 3	PHE A 214 TYR A 233 PRO A 216	None	1.05A	14.15 1.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	5uhk	O-GLCNACASE TIM-BARREL DOMAIN (Homo sapiens)	3 / 3	PHE A 214 TYR A 233 PRO A 216	None	0.99A	20.11 2.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	5uhp	O-GLCNACASE TIM-BARREL DOMAIN (Homo sapiens)	3 / 3	PHE A 214 TYR A 233 PRO A 216	None	1.12A	21.48 1.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	5vvo	PROTEIN O-GLCNACASE (Homo sapiens)	3 / 3	PHE A 214 TYR A 233 PRO A 216	None	1.05A	18.72 2.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	2xyd	ANGIOTENSIN-CONVERTI NG ENZYME (Homo sapiens)	3 / 3	TRP A 335 ARG A 344 PHE A 337	PEG  A1622 ( 4.0A) None None	1.44A	15.41 14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	3pta	DNA (CYTOSINE-5)-METHYLT RANSFERASE 1 (Homo sapiens)	3 / 3	TRP A1498 ARG A1490 PHE A1492	None	1.15A	13.01 12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	3szb	ALDEHYDE DEHYDROGENASE (Homo sapiens)	3 / 3	TRP A 233 ARG A 229 PHE A 270	None	1.43A	18.31 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	4g1c	NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL (Homo sapiens)	3 / 3	TRP A  99 ARG A 217 PHE A  91	None	1.40A	20.22 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	4ztu	DNA POLYMERASE SUBUNIT GAMMA-2, MITOCHONDRIAL (Homo sapiens)	3 / 3	TRP B 241 ARG B 122 PHE B 254	None	1.45A	18.70 17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	5c53	POL GAMMA B (Homo sapiens)	3 / 3	TRP B 241 ARG B 122 PHE B 254	None	1.45A	12.56 12.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	5kn5	EPIREGULIN ANTIBODY LY3016859 FAB HEAVY CHAIN (Homo sapiens)	3 / 3	TRP A  47 ARG A  99 PHE A 105	None	1.20A	59.63 26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	5lkz	HISTONE ACETYLTRANSFERASE P300,HISTONE ACETYLTRANSFERASE P300 (Homo sapiens)	3 / 3	TRP A1649 ARG A1646 PHE A1170	None	1.48A	16.55 17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	5nug	CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 (Homo sapiens)	3 / 3	TRP A4185 ARG A4271 PHE A4268	None	1.42A	4.35 3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	6eoq	DIPEPTIDYL PEPTIDASE 9 (Homo sapiens)	3 / 3	TRP A 210 ARG A 188 PHE A 203	None	1.09A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	6eot	DIPEPTIDYL PEPTIDASE 8 (Homo sapiens)	3 / 3	TRP A 237 ARG A 215 PHE A 230	None	0.86A	undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	1jd0	CARBONIC ANHYDRASE XII (Homo sapiens)	4 / 6	TRP A   5 GLN A  92 THR A 200 PRO A 202	None AZM  A1400 (-3.2A) AZM  A1400 (-3.3A) None	0.69A	36.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	2iae	SERINE/THREONINE-PRO TEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM (Homo sapiens)	4 / 6	HIS B 217 ASN B 219 THR B 114 PRO B 113	None	1.23A	22.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	2it4	CARBONIC ANHYDRASE 1 (Homo sapiens)	4 / 6	TRP A   5 HIS A  64 GLN A  92 PRO A 202	None	0.70A	60.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	3da2	CARBONIC ANHYDRASE 13 (Homo sapiens)	4 / 6	TRP A   6 ASN A  68 GLN A  93 PRO A 203	None None 4MD  A 401 (-3.1A) 4MD  A 401 ( 4.9A)	0.93A	60.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	3f3s	LAMBDA-CRYSTALLIN HOMOLOG (Homo sapiens)	4 / 6	HIS A 145 ASN A 196 GLN A 199 PRO A 149	NAD  A 601 ( 4.5A) None None None	1.26A	20.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	4 / 6	ASN A  62 GLN A  67 THR A 200 PRO A 202	None None AZM  A 264 (-3.5A) None	1.11A	55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	4 / 6	TRP A   5 GLN A  67 THR A 200 PRO A 202	None None AZM  A 264 (-3.5A) None	1.13A	55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	4 / 6	TRP A   5 GLN A  92 THR A 200 PRO A 202	None AZM  A 264 (-4.1A) AZM  A 264 (-3.5A) None	0.29A	55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	3ml5	CARBONIC ANHYDRASE 7 (Homo sapiens)	4 / 6	TRP A   5 HIS A  64 THR A 200 PRO A 202	None None AZM  A 264 (-3.5A) None	1.15A	55.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	3uyq	CARBONIC ANHYDRASE 3 (Homo sapiens)	4 / 6	TRP A   5 GLN A  92 THR A 199 PRO A 201	None	0.39A	58.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	4ldq	METHYLTHIORIBOSE-1-P HOSPHATE ISOMERASE (Homo sapiens)	4 / 6	HIS A 167 ASN A 258 THR A 202 PRO A 204	None	1.17A	19.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	6 / 6	TRP A   5 HIS A  64 ASN A  67 GLN A  92 THR A 200 PRO A 202	None	0.37A	95.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	5cjf	CARBONIC ANHYDRASE 14 (Homo sapiens)	4 / 6	TRP A   5 GLN A  92 THR A 200 PRO A 202	None GOL  A 303 (-3.2A) GOL  A 303 ( 3.5A) None	0.53A	36.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	5er7	GAP JUNCTION BETA-2 PROTEIN (Homo sapiens)	4 / 6	TRP B  77 HIS B  73 GLN B 164 THR B 192	None	1.28A	18.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	5jn9	CARBONIC ANHYDRASE 4 (Homo sapiens)	4 / 6	TRP A   5 HIS A  64 GLN A  92 THR A 200	None None EZL  A 302 (-4.3A) EZL  A 302 (-3.9A)	0.43A	35.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	6fe1	CARBONIC ANHYDRASE 9 (Homo sapiens)	4 / 6	TRP A   5 GLN A  92 THR A 200 PRO A 202	None V14  A 302 (-3.8A) V14  A 302 (-3.5A) None	0.44A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2O_B_DHIB24_0 (INSULIN B CHAIN)	1bjx	PROTEIN DISULFIDE ISOMERASE (Homo sapiens)	4 / 6	GLY A 142 PHE A 155 LYS A 119 THR A 121	None	1.01A	10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2O_B_DHIB24_0 (INSULIN B CHAIN)	1czv	PROTEIN (COAGULATION FACTOR V) (Homo sapiens)	4 / 6	GLY A 115 PRO A 140 LYS A 141 THR A 142	None	0.96A	14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2O_B_DHIB24_0 (INSULIN B CHAIN)	3kci	PROBABLE E3 UBIQUITIN-PROTEIN LIGASE HERC2 (Homo sapiens)	4 / 6	GLY A4116 PRO A4134 LYS A4135 THR A4114	None	1.16A	6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2O_B_DHIB24_0 (INSULIN B CHAIN)	3rdv	CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 1 (Homo sapiens)	4 / 6	ARG A 107 GLY A 101 PRO A 113 LYS A 115	None	1.19A	23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2O_B_DHIB24_0 (INSULIN B CHAIN)	4fze	N26_I1 FAB HEAVY CHAIN (Homo sapiens)	4 / 6	GLY H  50 PHE H  33 PRO H  52 THR H  56	None	1.03A	9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2O_B_DHIB24_0 (INSULIN B CHAIN)	4or5	PROTEIN TAT AF4/FMR2 FAMILY MEMBER 4 (Human immunodeficiency virus 1; Homo sapiens)	4 / 6	GLY E  67 PRO C  18 LYS C  19 THR C  20	None	1.03A	24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2O_B_DHIB24_0 (INSULIN B CHAIN)	4wtv	PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-BETA,ENDOLYSIN,PHO SPHATIDYLINOSITOL 4-KINASE TYPE 2-BETA (Homo sapiens; Escherichia virus T4)	4 / 6	GLY A 145 PRO A 205 LYS A 206 THR A 207	None ATP  A1201 ( 4.5A) None None	1.31A	5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2O_B_DHIB24_0 (INSULIN B CHAIN)	5hzv	MALTOSE-BINDING PERIPLASMIC PROTEIN,ENDOGLIN (Escherichia coli; Homo sapiens)	4 / 6	GLY A 898 PRO A 942 LYS A 943 THR A 944	None	0.89A	4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	1lm7	SUBDOMAIN OF DESMOPLAKIN CARBOXY-TERMINAL DOMAIN (DPCT) (Homo sapiens)	3 / 3	TYR A2392 GLY A2395 PHE A2397	None	0.69A	9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	1qo6	FIBRONECTIN (Homo sapiens)	3 / 3	TYR A  47 GLY A  53 PHE A  96	None	0.65A	16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	1qoi	SNUCYP-20 (Homo sapiens)	3 / 3	TYR A  60 GLY A  62 PHE A  79	None	0.68A	15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	1xhn	CELLULAR REPRESSOR OF E1A-STIMULATED GENES (Homo sapiens)	3 / 3	TYR A 166 GLY A 169 PHE A 167	None	0.64A	11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	2x25	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (Homo sapiens)	3 / 3	TYR B  48 GLY B  50 PHE B  67	None	0.63A	10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	3j2i	PROLIFERATION-ASSOCI ATED PROTEIN 2G4 (Homo sapiens)	3 / 3	TYR A  21 GLY A  24 PHE A 117	None	0.71A	7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	3mql	FIBRONECTIN 1 (Homo sapiens)	3 / 3	TYR A 351 GLY A 357 PHE A 400	None	0.69A	11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	3te7	RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE] (Homo sapiens)	3 / 3	TYR A 132 GLY A 180 PHE A 131	None	0.66A	9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	3w4k	D-AMINO-ACID OXIDASE (Homo sapiens)	3 / 3	TYR A  95 GLY A 131 PHE A 133	None	0.60A	7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	4j5a	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL (Homo sapiens)	3 / 3	TYR X  90 GLY X  92 PHE X 109	None	0.68A	11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	5te1	ATP-CITRATE SYNTHASE (Homo sapiens)	3 / 3	TYR A 531 GLY A 535 PHE A 533	None	0.68A	3.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	5tet	ATP-CITRATE SYNTHASE (Homo sapiens)	3 / 3	TYR B 531 GLY B 535 PHE B 533	None	0.71A	7.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	6apx	MALTOSE-BINDING PERIPLASMIC PROTEIN,DUAL SPECIFICITY PROTEIN PHOSPHATASE 1 (Escherichia coli; Homo sapiens)	3 / 3	TYR A1218 GLY A1216 PHE A1214	None	0.65A	4.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	6bf6	INSULIN-DEGRADING ENZYME (Homo sapiens)	3 / 3	TYR A 127 GLY A 117 PHE A 115	None	0.66A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC32_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	4cmn	INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL-1 (Homo sapiens)	5 / 6	GLY A 347 GLY A 345 GLY A 356 GLY A 353 GLY A 357	None	1.23A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC32_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	5gwn	PROTEIN RCC2 (Homo sapiens)	5 / 6	GLY A 465 GLY A 463 GLY A 460 GLY A 138 GLY A 110	None	0.80A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	1e33	ARYLSULFATASE A (Homo sapiens)	3 / 3	SER P 406 GLY P 303 GLY P 309	None	0.53A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	1glo	CATHEPSIN S (Homo sapiens)	3 / 3	SER A  57 GLY A  62 GLY A  69	None	0.54A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	1wl4	ACETYL-COENZYME A ACETYLTRANSFERASE 2 (Homo sapiens)	3 / 3	SER A 123 GLY A  23 GLY A  19	None	0.43A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	1yb5	QUINONE OXIDOREDUCTASE (Homo sapiens)	3 / 3	SER A 158 GLY A 181 GLY A 320	NAP  A 801 (-2.7A) NAP  A 801 (-3.5A) NAP  A 801 ( 3.3A)	0.55A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	1yz4	DUAL SPECIFICITY PHOSPHATASE-LIKE 15 ISOFORM A (Homo sapiens)	3 / 3	SER A 143 GLY A 108 GLY A 110	None	0.57A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2a8i	THREONINE ASPARTASE 1 (Homo sapiens)	3 / 3	SER A 252 GLY A 264 GLY A 294	None	0.51A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2c0y	PROCATHEPSIN S (Homo sapiens)	3 / 3	SER A 156 GLY A 161 GLY A 168	None	0.55A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2hvz	SPLICING FACTOR, ARGININE/SERINE-RICH 7 (Homo sapiens)	3 / 3	SER A  65 GLY A  11 GLY A  13	None	0.56A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2ibu	ACETYL-COA ACETYLTRANSFERASE (Homo sapiens)	3 / 3	SER A 157 GLY A  57 GLY A  53	None	0.49A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2zb4	PROSTAGLANDIN REDUCTASE 2 (Homo sapiens)	3 / 3	SER A 161 GLY A 233 GLY A 254	None None NAP  A 500 (-3.1A)	0.49A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	3ovz	CATHEPSIN K (Homo sapiens)	3 / 3	SER A  24 GLY A  20 GLY A  91	None	0.55A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	4c2k	3-KETOACYL-COA THIOLASE, MITOCHONDRIAL (Homo sapiens)	3 / 3	SER A 123 GLY A  22 GLY A  18	None	0.45A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	4c2k	3-KETOACYL-COA THIOLASE, MITOCHONDRIAL (Homo sapiens)	3 / 3	SER A 359 GLY A 355 GLY A  57	None	0.56A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	4fww	MACROPHAGE-STIMULATI NG PROTEIN RECEPTOR (Homo sapiens)	3 / 3	SER A 513 GLY A 495 GLY A 492	None	0.42A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2ch6	N-ACETYL-D-GLUCOSAMI NE KINASE (Homo sapiens)	4 / 4	SER A 129 GLY A 128 GLY A 144 GLY A 151	None GLC  A1001 (-3.6A) None None	0.74A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2dgx	KIAA0430 PROTEIN (Homo sapiens)	4 / 4	SER A 550 GLY A 549 GLY A 552 GLY A 634	None	0.83A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2djr	ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	4 / 4	SER A  71 GLY A  72 GLY A   7 GLY A  47	None	0.84A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2ee4	RHO GTPASE ACTIVATING PROTEIN 5 VARIANT (Homo sapiens)	4 / 4	SER A   2 GLY A   1 GLY A   4 GLY A  14	None	0.73A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2k7n	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 1 (Homo sapiens)	4 / 4	SER A 182 GLY A 181 GLY A 172 GLY A 177	None	0.88A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2zb4	PROSTAGLANDIN REDUCTASE 2 (Homo sapiens)	4 / 4	SER A 161 GLY A 162 GLY A 233 GLY A 254	None NAP  A 500 ( 4.7A) None NAP  A 500 (-3.1A)	0.73A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	3edy	TRIPEPTIDYL-PEPTIDAS E 1 (Homo sapiens)	4 / 4	SER A 456 GLY A 473 GLY A 389 GLY A 409	None	0.90A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	3vi3	INTEGRIN ALPHA-5 (Homo sapiens)	4 / 4	SER A 437 GLY A 439 GLY A 416 GLY A 382	None	0.90A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	4f9o	HEXOKINASE-1 (Homo sapiens)	4 / 4	SER A 415 GLY A 414 GLY A 299 GLY A 233	0NZ  A1002 (-2.6A) 0NZ  A1002 (-3.1A) None BGC  A1001 ( 3.8A)	0.89A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	4nen	INTEGRIN ALPHA-X (Homo sapiens)	4 / 4	SER A 353 GLY A 352 GLY A 359 GLY A 349	None	0.85A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	4u1r	ATP-DEPENDENT 6-PHOSPHOFRUCTOKINAS E, PLATELET TYPE (Homo sapiens)	4 / 4	SER A 189 GLY A 186 GLY A 312 GLY A  89	None	0.92A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	4um8	INTEGRIN ALPHA-V (Homo sapiens)	4 / 4	SER A 241 GLY A 242 GLY A 172 GLY A 181	None	0.88A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	4wk4	INTEGRIN ALPHA-5 (Homo sapiens)	4 / 4	SER A 437 GLY A 439 GLY A 416 GLY A 382	None	0.87A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	5uak	CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (Homo sapiens)	4 / 4	SER A 459 GLY A 458 GLY A 461 GLY A 463	None	0.79A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	6bdz	DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 10 (Homo sapiens)	4 / 4	SER A 339 GLY A 338 GLY A 341 GLY A 334	None	0.93A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	6dnh	PRE-MRNA 3' END PROCESSING PROTEIN WDR33 (Homo sapiens)	4 / 4	SER B 263 GLY B 262 GLY B 244 GLY B 224	None	0.91A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	6f9n	PRE-MRNA 3' END PROCESSING PROTEIN WDR33 (Homo sapiens)	4 / 4	SER B 263 GLY B 262 GLY B 244 GLY B 242	None	0.91A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_D_DHID8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	6fn1	HUMAN-MOUSE CHIMERIC ABCB1 (ABCBHM) (Homo sapiens)	4 / 4	SER A1070 GLY A1069 GLY A1072 GLY A1248	None	0.80A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KL3_A_DHIA403_0 (GLUCURONOXYLANASE XYNC)	3zkj	ANKYRIN REPEAT AND SOCS BOX PROTEIN 9 (Homo sapiens)	4 / 4	GLY A 168 TYR A 172 GLY A 196 ASP A 200	None	1.35A	20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KL3_A_DHIA403_0 (GLUCURONOXYLANASE XYNC)	5wy8	INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN-LIKE 1 (Homo sapiens)	4 / 4	GLY B 311 TYR B 273 GLY B 275 ASP B 276	None	1.19A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	1by2	MAC-2 BINDING PROTEIN (Homo sapiens)	3 / 3	LEU A  37 TRP A  35 GLY A 102	None	0.75A	9.40 8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	1nug	PROTEIN-GLUTAMINE GLUTAMYLTRANSFERASE E (Homo sapiens)	3 / 3	LEU A 256 TRP A 259 GLY A 230	None None CA  A 703 ( 4.4A)	0.58A	4.95 2.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	1nvp	TRANSCRIPTION INITIATION FACTOR IIA ALPHA CHAIN TRANSCRIPTION INITIATION FACTOR IIA GAMMA CHAIN (Homo sapiens; Homo sapiens)	3 / 3	LEU B  42 TRP B  46 GLY D  12	None	0.78A	21.31 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	1uw0	DNA LIGASE III (Homo sapiens)	3 / 3	LEU A  73 TRP A  79 GLY A  78	None	0.71A	18.80 11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	1zcm	CALPAIN 1, LARGE [CATALYTIC] SUBUNIT (Homo sapiens)	3 / 3	LEU A 118 TRP A 116 GLY A 207	None None C1N  A1115 (-3.3A)	0.72A	6.62 4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	2fg5	RAS-RELATED PROTEIN RAB-31 (Homo sapiens)	3 / 3	LEU A 103 TRP A  99 GLY A  12	None	0.80A	12.23 6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	2ifg	HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR (Homo sapiens)	3 / 3	LEU A 229 TRP A 227 GLY A 248	None	0.76A	7.92 5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	2p0r	CALPAIN-9 (Homo sapiens)	3 / 3	LEU A 100 TRP A  98 GLY A 189	None	0.65A	8.79 5.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	2q3z	TRANSGLUTAMINASE 2 (Homo sapiens)	3 / 3	LEU A 261 TRP A 264 GLY A 235	None	0.53A	5.21 2.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	3bvh	FIBRINOGEN GAMMA CHAIN (Homo sapiens)	3 / 3	LEU C 276 TRP C 334 GLY C 342	None	0.73A	5.46 8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	3e73	LANC-LIKE PROTEIN 1 (Homo sapiens)	3 / 3	LEU A 321 TRP A 275 GLY A 281	None	0.79A	10.40 2.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	3hym	CELL DIVISION CYCLE PROTEIN 16 HOMOLOG (Homo sapiens)	3 / 3	LEU B 458 TRP B 418 GLY B 416	None	0.78A	6.73 4.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	3jbz	SERINE/THREONINE-PRO TEIN KINASE MTOR (Homo sapiens)	3 / 3	LEU A1453 TRP A1449 GLY A1441	None	0.78A	4.33 1.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	4f7o	COP9 SIGNALOSOME COMPLEX SUBUNIT 5 (Homo sapiens)	3 / 3	LEU A 147 TRP A 146 GLY A 144	None	0.78A	9.73 5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	4fo0	ACTIN-RELATED PROTEIN 8 (Homo sapiens)	3 / 3	LEU A 583 TRP A 586 GLY A  61	CL  A 711 ( 4.7A) None None	0.78A	5.70 2.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	4ykn	PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA,PHOSPHATIDYLIN OSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM FUSION PROTEIN (Homo sapiens)	3 / 3	LEU A1452 TRP A1424 GLY A1425	None	0.65A	3.04 1.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	5fur	TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 (Homo sapiens; Homo sapiens)	3 / 3	LEU B  42 TRP B  46 GLY D  12	None	0.79A	17.02 17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	5i6z	SODIUM-DEPENDENT SEROTONIN TRANSPORTER (Homo sapiens)	3 / 3	LEU A 405 TRP A 103 GLY A 100	None	0.79A	7.13 3.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	5j6s	ENDOPLASMIC RETICULUM AMINOPEPTIDASE 2 (Homo sapiens)	3 / 3	LEU A 791 TRP A 777 GLY A 782	None	0.75A	6.27 1.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	5xgj	PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM (Homo sapiens)	3 / 3	LEU A 452 TRP A 424 GLY A 425	None	0.70A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	5y2z	LEUCINE-RICH GLIOMA-INACTIVATED PROTEIN 1 (Homo sapiens)	3 / 3	LEU B 385 TRP B 460 GLY B 461	None	0.79A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	5y31	LEUCINE-RICH GLIOMA-INACTIVATED PROTEIN 1 (Homo sapiens)	3 / 3	LEU B 385 TRP B 460 GLY B 461	None	0.78A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	5ze3	LYSYL OXIDASE HOMOLOG 2 (Homo sapiens)	3 / 3	LEU A 357 TRP A 355 GLY A 421	None	0.62A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	6bdt	CALPAIN-3 (Homo sapiens)	3 / 3	LEU A 132 TRP A 130 GLY A 221	None	0.74A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_H_DHIH3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	6etx	DNA HELICASE INO80 (Homo sapiens)	3 / 3	LEU G 916 TRP G 913 GLY G1053	None	0.76A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	1by2	MAC-2 BINDING PROTEIN (Homo sapiens)	3 / 3	LEU A  37 TRP A  35 GLY A 102	None	0.77A	9.40 8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	1nug	PROTEIN-GLUTAMINE GLUTAMYLTRANSFERASE E (Homo sapiens)	3 / 3	LEU A 256 TRP A 259 GLY A 230	None None CA  A 703 ( 4.4A)	0.51A	4.95 2.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	1nvp	TRANSCRIPTION INITIATION FACTOR IIA ALPHA CHAIN TRANSCRIPTION INITIATION FACTOR IIA GAMMA CHAIN (Homo sapiens; Homo sapiens)	3 / 3	LEU B  42 TRP B  46 GLY D  12	None	0.73A	21.31 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	1uw0	DNA LIGASE III (Homo sapiens)	3 / 3	LEU A  73 TRP A  79 GLY A  78	None	0.71A	18.80 11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	1zcm	CALPAIN 1, LARGE [CATALYTIC] SUBUNIT (Homo sapiens)	3 / 3	LEU A 118 TRP A 116 GLY A 207	None None C1N  A1115 (-3.3A)	0.80A	6.62 4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	2fg5	RAS-RELATED PROTEIN RAB-31 (Homo sapiens)	3 / 3	LEU A 103 TRP A  99 GLY A  12	None	0.79A	12.23 6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	2ifg	HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR (Homo sapiens)	3 / 3	LEU A 229 TRP A 227 GLY A 248	None	0.76A	7.92 5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	2p0r	CALPAIN-9 (Homo sapiens)	3 / 3	LEU A 100 TRP A  98 GLY A 189	None	0.74A	8.79 5.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	2q3z	TRANSGLUTAMINASE 2 (Homo sapiens)	3 / 3	LEU A 261 TRP A 264 GLY A 235	None	0.46A	5.21 2.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	3bvh	FIBRINOGEN GAMMA CHAIN (Homo sapiens)	3 / 3	LEU C 276 TRP C 334 GLY C 342	None	0.69A	5.46 8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	3e73	LANC-LIKE PROTEIN 1 (Homo sapiens)	3 / 3	LEU A 321 TRP A 275 GLY A 281	None	0.79A	10.40 2.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	3ghg	FIBRINOGEN GAMMA CHAIN (Homo sapiens)	3 / 3	LEU C 276 TRP C 334 GLY C 342	LEU  C 276 ( 0.6A) TRP  C 334 ( 0.5A) GLY  C 342 ( 0.0A)	0.78A	7.20 5.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	3hym	CELL DIVISION CYCLE PROTEIN 16 HOMOLOG (Homo sapiens)	3 / 3	LEU B 458 TRP B 418 GLY B 416	None	0.74A	6.73 4.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	3jbz	SERINE/THREONINE-PRO TEIN KINASE MTOR (Homo sapiens)	3 / 3	LEU A1453 TRP A1449 GLY A1441	None	0.82A	4.33 1.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	4f7o	COP9 SIGNALOSOME COMPLEX SUBUNIT 5 (Homo sapiens)	3 / 3	LEU A 147 TRP A 146 GLY A 144	None	0.78A	9.73 5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	4fo0	ACTIN-RELATED PROTEIN 8 (Homo sapiens)	3 / 3	LEU A 583 TRP A 586 GLY A  61	CL  A 711 ( 4.7A) None None	0.68A	5.70 2.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	4ykn	PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA,PHOSPHATIDYLIN OSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM FUSION PROTEIN (Homo sapiens)	3 / 3	LEU A1452 TRP A1424 GLY A1425	None	0.69A	3.04 1.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	5fur	TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 (Homo sapiens; Homo sapiens)	3 / 3	LEU B  42 TRP B  46 GLY D  12	None	0.75A	17.02 17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	5i6z	SODIUM-DEPENDENT SEROTONIN TRANSPORTER (Homo sapiens)	3 / 3	LEU A 405 TRP A 103 GLY A 100	None	0.77A	7.13 3.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	5j6s	ENDOPLASMIC RETICULUM AMINOPEPTIDASE 2 (Homo sapiens)	3 / 3	LEU A 791 TRP A 777 GLY A 782	None	0.79A	6.27 1.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	5xgj	PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM (Homo sapiens)	3 / 3	LEU A 452 TRP A 424 GLY A 425	None	0.73A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	5ze3	LYSYL OXIDASE HOMOLOG 2 (Homo sapiens)	3 / 3	LEU A 357 TRP A 355 GLY A 421	None	0.64A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L35_K_DHIK3_0 (GP41 N-PEPTIDE HIV ENTRY INHIBITOR PIE12)	6etx	DNA HELICASE INO80 (Homo sapiens)	3 / 3	LEU G 916 TRP G 913 GLY G1053	None	0.76A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	1kdu	PLASMINOGEN ACTIVATOR (Homo sapiens)	3 / 3	TYR A  50 PRO A  24 LEU A  23	None	0.92A	11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	1kfu	M-CALPAIN LARGE SUBUNIT (Homo sapiens)	3 / 3	TYR L 215 PRO L 220 LEU L 217	None	0.93A	4.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	1uw4	UPF3X (Homo sapiens)	3 / 3	TYR A  94 PRO A  59 LEU A  58	None	0.88A	50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	2dcr	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FES/FPS (Homo sapiens)	3 / 3	TYR A  71 PRO A  82 LEU A  83	None	0.85A	12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	2y6e	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4 (Homo sapiens)	3 / 3	TYR A 863 PRO A 818 LEU A 821	None	0.77A	2.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	2ysx	SIGNALING INOSITOL POLYPHOSPHATE PHOSPHATASE SHIP II (Homo sapiens)	3 / 3	TYR A  47 PRO A  64 LEU A  63	None	0.86A	5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	3ihp	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5 (Homo sapiens)	3 / 3	TYR A 828 PRO A 594 LEU A 597	None	0.86A	1.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	3ndp	ADENYLATE KINASE ISOENZYME 4 (Homo sapiens)	3 / 3	TYR A 136 PRO A 142 LEU A 138	None	0.93A	4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	4fys	AMINOPEPTIDASE N (Homo sapiens)	3 / 3	TYR A 176 PRO A 148 LEU A 166	None	0.94A	3.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	5c7m	E3 UBIQUITIN-PROTEIN LIGASE ITCHY HOMOLOG POLYUBIQUITIN-C (Homo sapiens; Homo sapiens)	3 / 3	TYR A 609 PRO A 607 LEU B   8	None	0.90A	3.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	5gvb	WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1 (Homo sapiens)	3 / 3	TYR A 741 PRO A 638 LEU A 650	None	0.79A	1.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	5hmp	UNCONVENTIONAL MYOSIN-VC (Homo sapiens)	3 / 3	TYR A  77 PRO A  63 LEU A  66	None	0.77A	1.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	5ltl	C-C MOTIF CHEMOKINE 16 (Homo sapiens)	3 / 3	TYR A  19 PRO A  24 LEU A  27	None	0.93A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	5mto	INHIBITOR OF GROWTH PROTEIN 5 (Homo sapiens)	3 / 3	TYR A  10 PRO A  18 LEU A  21	None	0.93A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	5ogs	WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1 (Homo sapiens)	3 / 3	TYR A 741 PRO A 638 LEU A 650	None	0.79A	1.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEO_A_DHIA4_0 ((DPR)PY(DHI)PKDL(DGN ))	5ohk	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30,UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30,UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30 (Homo sapiens)	3 / 3	TYR A 434 PRO A 318 LEU A 321	None	0.84A	3.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H3D_A_DHIA601_0 (DUF2338 DOMAIN-CONTAINING PROTEIN)	3w4k	D-AMINO-ACID OXIDASE (Homo sapiens)	4 / 5	TYR A 128 ASN A  96 TYR A  95 PHE A 125	None	1.10A	22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H3D_A_DHIA601_0 (DUF2338 DOMAIN-CONTAINING PROTEIN)	5l6o	EPHRIN TYPE-B RECEPTOR 3 (Homo sapiens)	4 / 5	TYR A 748 ASN A 753 TYR A 754 PHE A 689	None None DIO  A1002 (-4.5A) DIO  A1002 (-4.7A)	1.35A	22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H3D_A_DHIA601_0 (DUF2338 DOMAIN-CONTAINING PROTEIN)	5nx2	GLUCAGON-LIKE PEPTIDE 1 RECEPTOR (Homo sapiens)	4 / 5	TYR A 250 ASN A 177 TYR A 178 PHE A 266	None	1.20A	20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H3D_A_DHIA601_0 (DUF2338 DOMAIN-CONTAINING PROTEIN)	6b3j	GLUCAGON-LIKE PEPTIDE 1 RECEPTOR (Homo sapiens)	4 / 5	TYR R 250 ASN R 177 TYR R 178 PHE R 266	None	1.29A	undetectable