POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	1vol	PROTEIN (TRANSCRIPTION FACTOR IIB (TFIIB)) (Homo sapiens)	5 / 11	ASP A 243 LEU A 299 LEU A 291 ARG A 295 PRO A 294	None	1.47A	17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	2gtr	CHROMODOMAIN Y-LIKE PROTEIN (Homo sapiens)	5 / 11	PHE A  71 ILE A  72 LEU A  75 ILE A  90 MET A  35	None	1.48A	15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	2px9	SUMO-ACTIVATING ENZYME SUBUNIT 2 (Homo sapiens)	5 / 11	ILE A 175 LEU A 258 ARG A 176 PRO A 208 ILE A 238	None	1.50A	16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	2y6e	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4 (Homo sapiens)	5 / 11	ASP A 367 ILE A 297 LEU A 301 LEU A 304 ILE A 359	None	1.30A	12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	3p8c	NCK-ASSOCIATED PROTEIN 1 (Homo sapiens)	5 / 11	ILE B1051 LEU B1055 LEU B 999 ILE B 910 MET B 907	None	1.19A	6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	4cem	REGULATOR OF NONSENSE TRANSCRIPTS 2 (Homo sapiens)	5 / 11	PHE A 229 ILE A 202 LEU A 198 LEU A 228 ILE A 181	None	1.25A	13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	4hzs	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	5 / 11	PHE A 271 ILE A 268 LEU A 243 LEU A 192 MET A 203	None	1.50A	13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	4ixu	ARGINASE-2, MITOCHONDRIAL (Homo sapiens)	5 / 11	ASP A 253 PHE A 255 ILE A 252 LEU A 314 MET A 219	MN  A 402 ( 2.0A) None None None None	1.44A	15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	4mfv	BETA-CATENIN-LIKE PROTEIN 1 (Homo sapiens)	5 / 11	MET A 387 PHE A 383 ILE A 382 LEU A 379 ILE A 503	None	1.00A	9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	4p5e	2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1 (Homo sapiens)	5 / 11	ASP A 155 PHE A 158 LEU A 163 LEU A 116 ILE A  42	None	1.22A	25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	4ykn	PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA,PHOSPHATIDYLIN OSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM FUSION PROTEIN (Homo sapiens)	5 / 11	MET A2005 PHE A2002 ILE A2019 LEU A1938 ILE A1819	None	1.35A	4.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	5jh5	LYSINE-SPECIFIC DEMETHYLASE 2B (Homo sapiens)	5 / 11	MET A1237 LEU A1270 LEU A1218 ILE A1225 MET A1191	None	1.34A	16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	5xgj	PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM (Homo sapiens)	5 / 11	MET A1005 PHE A1002 ILE A1019 LEU A 938 ILE A 819	None	1.32A	21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_D95A816_0 (GEPHYRIN)	6ez8	HUNTINGTIN (Homo sapiens)	5 / 11	PHE A1584 ILE A1585 LEU A1588 LEU A1571 ILE A1609	None	1.48A	18.18