POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1CET_A_CLQA1001_0 (PROTEIN (L-LACTATE DEHYDROGENASE))	1t2f	L-LACTATE DEHYDROGENASE B CHAIN (Homo sapiens)	5 / 9	VAL A  26 GLY A  27 ASP A  52 TYR A  83 ALA A  96	None NAD  A 401 ( 4.5A) NAD  A 401 (-2.5A) None NAD  A 401 ( 4.1A)	0.59A	30.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CET_A_CLQA1001_0 (PROTEIN (L-LACTATE DEHYDROGENASE))	3lpp	SUCRASE-ISOMALTASE (Homo sapiens)	5 / 9	VAL A 434 GLY A 437 ILE A 431 TYR A 441 ILE A 480	None	1.17A	16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CET_A_CLQA1001_0 (PROTEIN (L-LACTATE DEHYDROGENASE))	4md8	CASEIN KINASE II SUBUNIT ALPHA (Homo sapiens)	5 / 9	VAL E 293 ASP E 130 ILE E 133 ALA E 297 PHE E 324	None	1.19A	20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CET_A_CLQA1001_0 (PROTEIN (L-LACTATE DEHYDROGENASE))	4yj5	PYRUVATE KINASE PKM (Homo sapiens)	5 / 9	VAL A 509 GLY A 426 ALA A 427 PHE A 470 ILE A 451	None None None SER  A 603 (-4.3A) None	0.97A	21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CET_A_CLQA1001_0 (PROTEIN (L-LACTATE DEHYDROGENASE))	5ofb	MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 2 (Homo sapiens)	5 / 9	VAL B 410 GLY B 409 ILE B 456 TYR B 450 PHE B 468	None	1.17A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1jqe	HISTAMINE N-METHYLTRANSFERASE (Homo sapiens)	5 / 12	GLY A  61 TYR A  98 ILE A  59 VAL A 172 PHE A  19	SAH  A 400 ( 4.1A) None None None SAH  A 400 (-3.9A)	1.27A	23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1lt8	BETAINE-HOMOCYSTEINE METHYLTRANSFERASE (Homo sapiens)	5 / 12	GLY A 298 GLY A 297 ILE A 307 VAL A 275 ILE A 281	None	1.03A	19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1ne7	GLUCOSAMINE-6-PHOSPH ATE ISOMERASE (Homo sapiens)	5 / 12	GLY A 130 GLY A 129 ILE A 125 VAL A 199 PHE A  35	None	1.28A	20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2d7i	POLYPEPTIDE N-ACETYLGALACTOSAMIN YLTRANSFERASE 10 (Homo sapiens)	5 / 12	GLY A 112 TYR A 375 GLU A 156 ILE A 371 ILE A 115	None None UDP  A 705 (-3.6A) None None	1.18A	16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2fbm	Y CHROMOSOME CHROMODOMAIN PROTEIN 1, TELOMERIC ISOFORM B (Homo sapiens)	5 / 12	GLY A 344 VAL A 318 PHE A 334 ILE A 398 PHE A 341	None	1.04A	22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2fw2	TESTIS-SPECIFIC CHROMODOMAIN PROTEIN Y 2 (Homo sapiens)	5 / 12	GLY A  64 VAL A  38 PHE A  54 ILE A 118 PHE A  61	None	1.00A	22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2ozo	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	5 / 12	GLY A  44 GLY A  45 TYR A  69 VAL A 114 PHE A  11	None	1.15A	16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2x5y	ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1 (Homo sapiens)	5 / 12	GLY A 848 MET A 778 VAL A 876 PHE A 880 ILE A 879	None	1.17A	20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2yup	VINEXIN (Homo sapiens)	5 / 12	GLY A  64 ILE A  45 VAL A  73 PHE A  36 ILE A  42	None	1.27A	15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3k77	DNA REPAIR PROTEIN XRCC1 (Homo sapiens)	5 / 12	GLY A 143 ASN A  62 ILE A  43 VAL A   9 ILE A 130	None	1.28A	19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3k9b	LIVER CARBOXYLESTERASE 1 (Homo sapiens)	5 / 12	GLY A1209 GLY A1210 VAL A1047 PHE A1050 ILE A1121	None	1.26A	19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3ld8	BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6 (Homo sapiens)	5 / 12	GLY A 269 ASN A 293 VAL A  71 PHE A 156 PHE A 288	None	1.23A	24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3n2z	LYSOSOMAL PRO-X CARBOXYPEPTIDASE (Homo sapiens)	5 / 12	GLY B 413 GLY B 412 ILE B 407 VAL B 213 ILE B 206	None	1.27A	19.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3te7	RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE] (Homo sapiens)	7 / 12	GLY A 149 GLY A 150 MET A 154 TYR A 155 ASN A 161 GLU A 193 ILE A 194	FAD  A 232 (-3.6A) FAD  A 232 (-3.6A) None FAD  A 232 (-4.6A) None FAD  A 232 ( 3.1A) None	0.36A	98.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3te7	RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE] (Homo sapiens)	5 / 12	VAL A  69 GLN A 122 PHE A 126 ILE A 128 PHE A 178	None TE7  A   1 ( 4.3A) TE7  A   1 (-4.3A) None TE7  A   1 (-3.6A)	0.51A	98.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4bkx	HISTONE DEACETYLASE 1 (Homo sapiens)	5 / 12	GLY B 300 MET B  30 VAL B 133 ILE B  35 PHE B 109	ACT  B 601 ( 4.8A) None None None None	1.16A	20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4lde	LYSOZYME, BETA-2 ADRENERGIC RECEPTOR (Homo sapiens; Escherichia virus T4)	5 / 12	GLY A1315 ASN A1312 PHE A1208 ILE A1121 PHE A1290	None P0G  A1401 (-2.9A) None None P0G  A1401 ( 4.9A)	1.28A	20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4q6r	SPHINGOSINE-1-PHOSPH ATE LYASE 1 (Homo sapiens)	5 / 12	GLY A 398 GLY A 399 TYR A 164 GLU A 185 ILE A 184	None	1.13A	20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4y7i	MYOTUBULARIN-RELATED PROTEIN 8 (Homo sapiens)	5 / 12	GLY A 365 VAL A 483 PHE A 417 ILE A 354 PHE A 419	None	1.25A	20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5dot	CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL (Homo sapiens)	5 / 12	GLY A1339 TYR A1494 ILE A1342 VAL A1477 PHE A1489	None	1.18A	9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5exr	DNA POLYMERASE ALPHA CATALYTIC SUBUNIT DNA POLYMERASE ALPHA SUBUNIT B (Homo sapiens; Homo sapiens)	5 / 12	GLU C 615 ILE C 558 VAL C 653 GLN D 248 PHE C 642	None	1.25A	12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5gve	DNA TOPOISOMERASE 3-BETA-1 (Homo sapiens)	5 / 12	GLY A 541 ASN A 539 GLN A 196 PHE A 200 ILE A 212	None	1.26A	18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_B_CLQB303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2c11	MEMBRANE COPPER AMINE OXIDASE (Homo sapiens)	5 / 11	HIS A 160 PHE A  97 GLY A 390 TYR A 394 GLU A 367	CU  A1741 (-3.5A) None None None None	1.33A	15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_B_CLQB303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3ddu	PROLYL ENDOPEPTIDASE (Homo sapiens)	5 / 11	HIS A 515 PHE A 476 ILE A 478 GLY A 556 GLY A 553	None 552  A 901 (-3.5A) None None None	1.40A	15.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FGL_B_CLQB303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3te7	RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE] (Homo sapiens)	6 / 11	GLY A 149 GLY A 150 MET A 154 TYR A 155 ASN A 161 GLU A 193	FAD  A 232 (-3.6A) FAD  A 232 (-3.6A) None FAD  A 232 (-4.6A) None FAD  A 232 ( 3.1A)	0.15A	98.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FGL_B_CLQB303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3te7	RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE] (Homo sapiens)	5 / 11	HIS A  72 GLN A 122 PHE A 126 ILE A 128 PHE A 178	None TE7  A   1 ( 4.3A) TE7  A   1 (-4.3A) None TE7  A   1 (-3.6A)	0.21A	98.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_B_CLQB303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5gve	DNA TOPOISOMERASE 3-BETA-1 (Homo sapiens)	5 / 11	GLN A 196 PHE A 200 ILE A 212 GLY A 541 ASN A 539	None	1.42A	18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_B_CLQB303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5k1c	WD REPEAT-CONTAINING PROTEIN 48 (Homo sapiens)	5 / 11	HIS B 374 PHE B 507 GLY B 463 GLY B 464 ASN B 504	None	1.45A	17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_B_CLQB303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5w21	FIBROBLAST GROWTH FACTOR 23 (Homo sapiens)	5 / 11	HIS B  52 GLN B  67 PHE B 169 GLY B  38 GLY B  37	None	1.25A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1h2t	80 KDA NUCLEAR CAP BINDING PROTEIN (Homo sapiens)	4 / 5	GLY C 102 GLY C 101 ASN C  97 GLU C 106	None	1.16A	17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1ntg	TYROSYL-TRNA SYNTHETASE (Homo sapiens)	4 / 5	GLY A 166 GLY A 167 ASN A 168 GLU A 141	None	1.17A	21.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3te7	RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE] (Homo sapiens)	5 / 5	GLY A 149 GLY A 150 MET A 154 ASN A 161 GLU A 193	FAD  A 232 (-3.6A) FAD  A 232 (-3.6A) None None FAD  A 232 ( 3.1A)	0.17A	98.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3zk6	BCL-2-LIKE PROTEIN 1 (Homo sapiens)	4 / 5	GLY A 148 GLY A 147 MET A 170 GLU A  98	None	1.14A	22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4hyy	MEIOTIC RECOMBINATION PROTEIN DMC1/LIM15 HOMOLOG (Homo sapiens)	4 / 5	GLY A 290 GLY A 289 MET A 226 ASN A 268	None	1.05A	22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4p0j	INTERLEUKIN-36 RECEPTOR ANTAGONIST/INTERLEUK IN-36 GAMMA CHIMERA PROTEIN (Homo sapiens)	4 / 5	GLY A  63 GLY A  64 ASN A  84 GLU A  41	None	0.51A	21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4u2n	ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17,NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN 1 (Homo sapiens)	4 / 5	GLY A  71 GLY A  69 ASN A  66 GLU A  75	None	1.11A	19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5dot	CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL (Homo sapiens)	4 / 5	GLY A  79 GLY A  78 ASN A  98 GLU A  82	None	1.00A	9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5la7	HEPARANASE (Homo sapiens)	4 / 5	GLY A  95 GLY A  96 ASN A  64 GLU A 221	None 6S6  A 613 (-3.2A) None None	1.10A	18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5nug	CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 (Homo sapiens)	4 / 5	GLY A2201 GLY A2200 MET A2373 GLU A2205	None None ATP  A4802 (-3.4A) None	1.31A	4.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5oa3	EUKARYOTIC TRANSLATION INITIATION FACTOR 2D (Homo sapiens)	4 / 5	GLY 0  67 GLY 0  68 ASN 0 181 GLU 0  46	None	0.90A	17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5wvo	DNA (CYTOSINE-5)-METHYLT RANSFERASE 1 (Homo sapiens)	4 / 5	GLY C 451 GLY C 452 ASN C 383 GLU C 450	None	1.00A	22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1tye	INTEGRIN BETA-3 (Homo sapiens)	4 / 8	GLY B 221 PHE B 248 ILE B 226 PHE B 308	None	0.80A	19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1zc4	RAS-RELATED PROTEIN RAL-A (Homo sapiens)	4 / 8	GLY A  21 VAL A  92 PHE A  83 ILE A  18	None	0.79A	21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3hig	AMILORIDE-SENSITIVE AMINE OXIDASE (Homo sapiens)	4 / 8	GLY A 524 PHE A 701 ILE A 346 PHE A 702	None	0.93A	16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3kbh	ANGIOTENSIN-CONVERTI NG ENZYME 2 (Homo sapiens)	4 / 8	GLY A 405 VAL A 404 HIS A 401 ILE A 379	None	0.89A	16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3nxp	PRETHROMBIN-1 (Homo sapiens)	4 / 8	ASN A 221 GLY A 224 PHE A 280 PHE A 281	None	0.84A	20.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3te7	RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE] (Homo sapiens)	8 / 8	ASN A  66 GLY A  68 VAL A  69 HIS A  72 GLN A 122 PHE A 126 ILE A 128 PHE A 178	None TE7  A   1 ( 4.1A) None None TE7  A   1 ( 4.3A) TE7  A   1 (-4.3A) None TE7  A   1 (-3.6A)	0.53A	98.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4cak	INTEGRIN BETA-3 (Homo sapiens)	4 / 8	GLY B 221 PHE B 248 ILE B 226 PHE B 308	None	0.82A	15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4nen	INTEGRIN ALPHA-X INTEGRIN BETA-2 (Homo sapiens; Homo sapiens)	4 / 8	GLY A 412 PHE B 247 ILE A 435 PHE B 245	None	0.82A	11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4um8	INTEGRIN BETA-6 (Homo sapiens)	4 / 8	GLY B 224 PHE B 251 ILE B 229 PHE B 311	None	0.63A	15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5e6s	INTEGRIN ALPHA-L INTEGRIN BETA-2 (Homo sapiens; Homo sapiens)	4 / 8	GLY A 406 PHE B 247 ILE A 431 PHE B 245	None	0.90A	15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5ei3	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E (Homo sapiens)	4 / 8	ASN A 213 GLY A 196 VAL A 216 ILE A 193	None	0.88A	18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5wch	PROBABLE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE FAF-X (Homo sapiens)	4 / 8	GLY A1558 VAL A1557 GLN A1573 ILE A1572	None	0.87A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	6c90	EXOSOME RNA HELICASE MTR4,EXOSOME RNA HELICASE MTR4 (Homo sapiens)	4 / 8	GLY A 263 VAL A 264 ILE A 270 PHE A 281	None	0.92A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	6d6q	EXOSOME COMPLEX COMPONENT RRP40 (Homo sapiens)	4 / 8	ASN G 234 GLY G 232 VAL G 117 ILE G 193	None	0.89A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	6d6q	EXOSOME RNA HELICASE MTR4 (Homo sapiens)	4 / 8	GLY M 263 VAL M 264 ILE M 270 PHE M 281	None	0.70A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1orf	GRANZYME A (Homo sapiens)	4 / 7	GLY A  44 VAL A  31 PHE A 209 ILE A  47	None	0.79A	21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1pl0	BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH (Homo sapiens)	4 / 7	ASN A 463 GLY A 459 ILE A 536 PHE A 542	None	0.84A	17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1tye	INTEGRIN BETA-3 (Homo sapiens)	4 / 7	GLY B 221 PHE B 248 ILE B 226 PHE B 308	None	0.74A	19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1zc4	RAS-RELATED PROTEIN RAL-A (Homo sapiens)	4 / 7	GLY A  21 VAL A  92 PHE A  83 ILE A  18	None	0.80A	21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3bjc	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE (Homo sapiens)	5 / 7	GLY A 819 VAL A 818 GLN A 817 ILE A 813 PHE A 787	None None WAN  A 901 (-3.1A) WAN  A 901 ( 4.3A) None	1.46A	13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3fhc	NUCLEAR PORE COMPLEX PROTEIN NUP214 (Homo sapiens)	4 / 7	GLY A 210 VAL A 209 ILE A 229 PHE A 287	None	0.87A	21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3hig	AMILORIDE-SENSITIVE AMINE OXIDASE (Homo sapiens)	4 / 7	GLY A 524 PHE A 701 ILE A 346 PHE A 702	None	0.89A	16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3nxp	PRETHROMBIN-1 (Homo sapiens)	4 / 7	ASN A 221 GLY A 224 PHE A 280 PHE A 281	None	0.85A	20.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FGL_D_CLQD303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3te7	RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE] (Homo sapiens)	7 / 7	ASN A  66 GLY A  68 VAL A  69 GLN A 122 PHE A 126 ILE A 128 PHE A 178	None TE7  A   1 ( 4.1A) None TE7  A   1 ( 4.3A) TE7  A   1 (-4.3A) None TE7  A   1 (-3.6A)	0.63A	98.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3v4v	INTEGRIN BETA-7 (Homo sapiens)	4 / 7	GLY B 241 PHE B 267 ILE B 246 PHE B 327	None	0.70A	18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4cak	INTEGRIN BETA-3 (Homo sapiens)	4 / 7	GLY B 221 PHE B 248 ILE B 226 PHE B 308	None	0.76A	15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4nen	INTEGRIN ALPHA-X INTEGRIN BETA-2 (Homo sapiens; Homo sapiens)	4 / 7	GLY A 412 PHE B 247 ILE A 435 PHE B 245	None	0.77A	11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1ryo	SEROTRANSFERRIN (Homo sapiens)	4 / 6	GLY A 258 ASN A  55 GLU A 260 ILE A 263	None	0.87A	20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1w8d	2,4-DIENOYL-COA REDUCTASE, MITOCHONDRIAL PRECURSOR (Homo sapiens)	4 / 6	GLY A  68 GLY A  67 ASN A 144 ILE A 103	None None NAP  A1330 (-3.2A) None	0.74A	25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2dmm	PROTEIN DISULFIDE-ISOMERASE A3 (Homo sapiens)	4 / 6	GLY A 120 GLY A 121 GLU A 119 ILE A 104	None	0.93A	20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2eko	HISTONE ACETYLTRANSFERASE HTATIP (Homo sapiens)	4 / 6	GLY A   8 GLY A   7 GLU A   9 ILE A  10	None	0.98A	18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2fe5	PRESYNAPTIC PROTEIN SAP102 (Homo sapiens)	4 / 6	GLY A 263 GLY A 264 GLU A 262 ILE A 260	None	0.96A	14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2i7t	CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 73 KDA SUBUNIT (Homo sapiens)	4 / 6	GLY A 233 GLY A 234 ASN A 350 ILE A 266	None	0.87A	18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2nmp	CYSTATHIONINE GAMMA-LYASE (Homo sapiens)	4 / 6	GLY A 202 ASN A 228 GLU A 170 ILE A 169	None	0.96A	20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3h1v	GLUCOKINASE (Homo sapiens)	4 / 6	GLY X 229 GLY X 227 GLU X 290 ILE X 293	GLC  X 500 ( 3.8A) None GLC  X 500 (-3.1A) None	0.86A	19.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3te7	RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE] (Homo sapiens)	6 / 6	GLY A 149 GLY A 150 MET A 154 ASN A 161 GLU A 193 ILE A 194	FAD  A 232 (-3.6A) FAD  A 232 (-3.6A) None None FAD  A 232 ( 3.1A) None	0.20A	98.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4d8o	ANKYRIN-2 (Homo sapiens)	4 / 6	GLY A1135 GLY A1136 ASN A1129 GLU A1152	None	0.97A	17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4f9o	HEXOKINASE-1 (Homo sapiens)	4 / 6	GLY A 681 GLY A 679 GLU A 742 ILE A 745	BGC  A1003 ( 3.8A) 0NZ  A1004 (-3.2A) BGC  A1003 (-2.7A) None	0.93A	12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4p0j	INTERLEUKIN-36 RECEPTOR ANTAGONIST/INTERLEUK IN-36 GAMMA CHIMERA PROTEIN (Homo sapiens)	4 / 6	GLY A  63 GLY A  64 ASN A  84 GLU A  41	None	0.63A	21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4q6r	SPHINGOSINE-1-PHOSPH ATE LYASE 1 (Homo sapiens)	4 / 6	GLY A 398 GLY A 399 GLU A 185 ILE A 184	None	0.93A	20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5dot	CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL (Homo sapiens)	4 / 6	GLY A  79 GLY A  78 ASN A  98 GLU A  82	None	0.98A	9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5oa3	EUKARYOTIC TRANSLATION INITIATION FACTOR 2D (Homo sapiens)	4 / 6	GLY 0  67 GLY 0  68 ASN 0 181 GLU 0  46	None	0.92A	17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5wvo	DNA (CYTOSINE-5)-METHYLT RANSFERASE 1 (Homo sapiens)	4 / 6	GLY C 451 GLY C 452 ASN C 383 GLU C 450	None	0.90A	22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5y31	DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 22 (Homo sapiens)	4 / 6	GLY A 430 GLY A 431 ASN A 526 ILE A 378	None None CA  A 803 (-3.2A) None	0.99A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_D_CLQD304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1f59	IMPORTIN BETA-1 (Homo sapiens)	4 / 4	LYS A 191 ASN A 188 VAL A 233 ASP A 230	None	1.36A	18.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FGL_D_CLQD304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3te7	RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE] (Homo sapiens)	4 / 4	LYS A  22 ASN A  23 VAL A  26 ASP A  27	None	0.09A	98.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	1cks	CYCLIN-DEPENDENT KINASE SUBUNIT, TYPE 2 (Homo sapiens)	3 / 3	MET A  38 GLU A  42 LEU A  46	None	0.72A	20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	1exx	RETINOIC ACID RECEPTOR GAMMA-2 (Homo sapiens)	3 / 3	MET A 323 GLU A 327 LEU A 331	None	0.48A	15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	1fxl	PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGEN HUD (Homo sapiens)	3 / 3	MET A  50 GLU A  54 LEU A  58	None	0.81A	16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	1fxl	PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGEN HUD (Homo sapiens)	3 / 3	MET A 136 GLU A 140 LEU A 144	None	0.79A	16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	1xap	RETINOIC ACID RECEPTOR BETA (Homo sapiens)	3 / 3	MET A 314 GLU A 318 LEU A 322	None	0.34A	15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	2ast	CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 1 (Homo sapiens)	3 / 3	MET C3038 GLU C3042 LEU C3046	None	0.76A	19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	2w5h	SERINE/THREONINE-PRO TEIN KINASE NEK2 (Homo sapiens)	3 / 3	MET A  44 GLU A  48 LEU A  52	None	0.68A	16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	3a6p	EXPORTIN-5 (Homo sapiens)	3 / 3	MET A  82 GLU A  86 LEU A  90	None	0.39A	5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	3cuq	VACUOLAR PROTEIN-SORTING-ASSO CIATED PROTEIN 36 (Homo sapiens)	3 / 3	MET B 264 GLU B 268 LEU B 272	None	0.51A	17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	3f7p	PLECTIN-1 (Homo sapiens)	3 / 3	MET A 185 GLU A 189 LEU A 193	None	0.44A	13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	3hi9	ELAV-LIKE PROTEIN 1 (Homo sapiens)	3 / 3	MET A  31 GLU A  35 LEU A  39	None	0.61A	22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	3jbz	SERINE/THREONINE-PRO TEIN KINASE MTOR (Homo sapiens)	3 / 3	MET A2387 GLU A2388 LEU A2392	None	0.80A	5.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	4ed5	ELAV-LIKE PROTEIN 1 (Homo sapiens)	3 / 3	MET A  31 GLU A  35 LEU A  39	None	0.58A	16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	4fxv	ELAV-LIKE PROTEIN 1 (Homo sapiens)	3 / 3	MET A  31 GLU A  35 LEU A  39	None	0.64A	22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	4hoo	LYSINE-SPECIFIC DEMETHYLASE 4D (Homo sapiens)	3 / 3	MET A  96 GLU A 100 LEU A 104	None	0.77A	14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	4lxl	LYSINE-SPECIFIC DEMETHYLASE 4B (Homo sapiens)	3 / 3	MET A  93 GLU A  97 LEU A 101	None	0.75A	12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	4q58	PLECTIN (Homo sapiens)	3 / 3	MET A 158 GLU A 162 LEU A 166	None	0.58A	14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	4xdo	LYSINE-SPECIFIC DEMETHYLASE 4C (Homo sapiens)	3 / 3	MET A  94 GLU A  98 LEU A 102	None	0.63A	18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	4z6g	MICROTUBULE-ACTIN CROSS-LINKING FACTOR 1, ISOFORMS 1/2/3/5 (Homo sapiens)	3 / 3	MET A 161 GLU A 165 LEU A 169	None	0.50A	20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	5k13	RETINOIC ACID RECEPTOR ALPHA (Homo sapiens)	3 / 3	MET A 321 GLU A 325 LEU A 329	None	0.79A	15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	5mra	SORCIN (Homo sapiens)	3 / 3	MET A  90 GLU A  94 LEU A  98	None MG  A 202 (-3.9A) None	0.78A	21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	5uan	RETINOIC ACID RECEPTOR BETA (Homo sapiens)	3 / 3	MET B 314 GLU B 318 LEU B 322	None	0.46A	12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	3 / 3	MET A 323 GLU A 327 LEU A 331	None	0.47A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_C_CLQC1079_0 (SAPOSIN-B)	2k42	WISKOTT-ALDRICH SYNDROME PROTEIN ESPFU (Homo sapiens; Escherichia coli)	4 / 5	ARG A  35 MET B  84 GLU A  68 LEU A  32	None	1.34A	20.25