POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	1fgg	GLUCURONYLTRANSFERAS E I (Homo sapiens)	4 / 6	HIS A 308 ALA A 254 ALA A 193 THR A  81	UNX  A 338 ( 3.2A) None None None	0.93A	21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	1v84	GALACTOSYLGALACTOSYL XYLOSYLPROTEIN 3-BETA-GLUCURONOSYLT RANSFERASE 1 (Homo sapiens)	4 / 6	HIS A 311 ALA A 256 ALA A 194 THR A  90	UDP  A 503 (-4.2A) None None None	0.93A	20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	3ow8	WD REPEAT-CONTAINING PROTEIN 61 (Homo sapiens)	4 / 6	ALA A  86 ALA A 109 THR A 123 PHE A 133	None	1.05A	20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	3ow8	WD REPEAT-CONTAINING PROTEIN 61 (Homo sapiens)	4 / 6	HIS A  87 ALA A 109 THR A 123 PHE A 133	None	1.06A	20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	3rzu	STAM-BINDING PROTEIN (Homo sapiens)	4 / 6	GLN A 304 ALA A 273 THR A 336 PHE A 267	None	1.04A	17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	3rzv	STAM-BINDING PROTEIN (Homo sapiens)	4 / 6	GLN A 304 ALA A 273 THR A 336 PHE A 267	None	1.03A	19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	4cby	HISTONE DEACETYLASE 4 (Homo sapiens)	4 / 6	GLN A 959 ALA A 905 ALA A 909 THR A 913	None	0.49A	21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	4d0p	COP9 SIGNALOSOME COMPLEX SUBUNIT 4 (Homo sapiens)	4 / 6	GLN A 289 ALA A 225 ALA A 229 THR A 233	None	0.86A	22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	4wj7	MALCAVERNIN (Homo sapiens)	4 / 6	HIS A 137 ALA A 158 ALA A 140 PHE A 217	None	0.96A	19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	5brr	TISSUE-TYPE PLASMINOGEN ACTIVATOR (Homo sapiens)	4 / 6	GLN E  30 ALA E  55 ALA E 195 PHE E  40	None	0.92A	20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	5van	BETA-KLOTHO (Homo sapiens)	4 / 6	ALA A 371 ALA A 415 THR A 458 PHE A 148	None	0.82A	10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	5wbg	CYTOCHROME P450 2B6 (Homo sapiens)	4 / 6	HIS A 397 ALA A 425 THR A 423 PHE A 413	None	0.98A	13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	1d5f	E6AP HECT CATALYTIC DOMAIN, E3 LIGASE (Homo sapiens)	5 / 8	MET A 802 LEU A 835 ILE A 770 LEU A 839 LEU A 826	None	1.41A	21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	1fuj	PR3 (Homo sapiens)	5 / 8	LEU A  59 GLN A  63 LEU A  33 THR A  54 LEU A 104	None	1.37A	19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	1h4o	PEROXIREDOXIN 5 (Homo sapiens)	5 / 8	HIS A  51 LEU A 161 GLN A 160 ILE A 158 LEU A  62	None	1.29A	15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	1pbw	PHOSPHATIDYLINOSITOL 3-KINASE (Homo sapiens)	4 / 8	GLN A 241 ILE A 227 LEU A 223 LEU A 293	None	0.75A	20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	1sqw	SACCHAROMYCES CEREVISIAE NIP7P HOMOLOG (Homo sapiens)	4 / 8	HIS A 175 LEU A 141 ILE A 139 LEU A 108	None	0.79A	19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	1w45	ANNEXIN A8 (Homo sapiens)	4 / 8	LEU A  30 ILE A  44 LEU A  48 LEU A  71	None	0.77A	21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	1w45	ANNEXIN A8 (Homo sapiens)	4 / 8	LEU A 102 ILE A 116 LEU A 120 LEU A 143	None	0.78A	21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	2b5m	DAMAGE-SPECIFIC DNA BINDING PROTEIN 1 (Homo sapiens)	5 / 8	LEU A1051 ILE A1094 LEU A1136 THR A1024 LEU A1043	None	1.24A	17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	2boa	CARBOXYPEPTIDASE A4 (Homo sapiens)	5 / 8	LEU A1064 ILE A1193 LEU A1297 THR A1082 LEU A1107	None	1.42A	19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	2bv5	TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 5 (Homo sapiens)	5 / 8	HIS A 471 LEU A 418 ILE A 416 LEU A 427 THR A 368	SCY  A 472 ( 4.2A) None None None None	1.39A	19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	2id5	LEUCINE RICH REPEAT NEURONAL 6A (Homo sapiens)	4 / 8	LEU A 274 ILE A 277 LEU A 253 LEU A 271	None	0.81A	24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	2km6	NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 7 (Homo sapiens)	5 / 8	MET A  93 LEU A  19 LEU A  16 THR A  73 LEU A  77	None	1.45A	14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	2n1g	DNA REPAIR PROTEIN REV1 (Homo sapiens)	4 / 8	LEU A1248 ILE A1210 LEU A1206 LEU A1240	None	0.80A	16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	2pcu	CARBOXYPEPTIDASE A4 (Homo sapiens)	5 / 8	LEU A  64 ILE A 193 LEU A 297 THR A  82 LEU A 107	None	1.46A	20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	2q8h	[PYRUVATE DEHYDROGENASE [LIPOAMIDE]] KINASE ISOZYME 1 (Homo sapiens)	4 / 8	LEU A  83 ILE A 191 LEU A 195 LEU A 121	None TF4  A 438 (-3.4A) None None	0.76A	20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_A_CL6A506_1 (CHOLESTEROL 24-HYDROXYLASE)	1b4q	PROTEIN (HUMAN THIOLTRANSFERASE) (Homo sapiens)	5 / 9	LEU A  42 VAL A  16 ILE A  31 ALA A  28 GLU A  30	None	1.15A	13.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDV_A_CL6A506_1 (CHOLESTEROL 24-HYDROXYLASE)	2q9g	CYTOCHROME P450 46A1 (Homo sapiens)	9 / 9	LEU A 112 PHE A 121 VAL A 126 LEU A 219 ILE A 301 ALA A 302 GLU A 305 ALA A 474 THR A 475	None None HEM  A 505 ( 3.8A) None None HEM  A 505 (-3.7A) None None None	0.42A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_A_CL6A506_1 (CHOLESTEROL 24-HYDROXYLASE)	2vpk	MYONEURIN (Homo sapiens)	5 / 9	LEU A  76 PHE A  73 VAL A  68 LEU A  42 ILE A  28	None	1.12A	15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_A_CL6A506_1 (CHOLESTEROL 24-HYDROXYLASE)	3cqg	NUCLEAR PORE COMPLEX PROTEIN NUP107 (Homo sapiens)	5 / 9	LEU A 736 LEU A 689 ILE A 720 ALA A 721 ALA A 686	None	1.12A	22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_A_CL6A506_1 (CHOLESTEROL 24-HYDROXYLASE)	3ifq	PLAKOGLOBIN (Homo sapiens)	5 / 9	LEU A 497 LEU A 459 ILE A 485 ALA A 484 ALA A 455	None	1.13A	23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_A_CL6A506_1 (CHOLESTEROL 24-HYDROXYLASE)	3t1p	ALPHA-1-ANTITRYPSIN (Homo sapiens)	5 / 9	LEU A  77 LEU A  30 ILE A  26 ALA A  58 THR A  59	None	1.04A	22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_A_CL6A506_1 (CHOLESTEROL 24-HYDROXYLASE)	4i6j	F-BOX/LRR-REPEAT PROTEIN 3 (Homo sapiens)	6 / 9	LEU B 144 PHE B 115 VAL B 117 ILE B 130 ALA B 126 ALA B 163	None	1.13A	21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_A_CL6A506_1 (CHOLESTEROL 24-HYDROXYLASE)	4nho	PROBABLE ATP-DEPENDENT RNA HELICASE DDX23 (Homo sapiens)	5 / 9	PHE A 445 VAL A 603 LEU A 480 GLU A 550 ALA A 475	None	1.10A	22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_A_CL6A506_1 (CHOLESTEROL 24-HYDROXYLASE)	5y3r	DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT (Homo sapiens)	5 / 9	LEU C1254 VAL C1337 LEU C1242 ILE C1301 ALA C1302	None	1.08A	7.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	1a27	17-BETA-HYDROXYSTERO ID-DEHYDROGENASE (Homo sapiens)	6 / 12	LEU A  22 PHE A  30 VAL A  86 THR A   3 ALA A 243 THR A 242	None	1.48A	22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	2oew	PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN (Homo sapiens)	5 / 12	LEU A  65 LEU A 124 ILE A 347 THR A 341 ALA A 128	None	0.92A	22.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	2q9g	CYTOCHROME P450 46A1 (Homo sapiens)	12 / 12	LEU A 112 PHE A 121 VAL A 126 LEU A 219 THR A 298 ILE A 301 ALA A 302 GLU A 305 THR A 306 ALA A 367 ALA A 474 THR A 475	None None HEM  A 505 ( 3.8A) None None None HEM  A 505 (-3.7A) None HEM  A 505 (-3.7A) HEM  A 505 (-3.5A) None None	0.39A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	2qtz	METHIONINE SYNTHASE REDUCTASE (Homo sapiens)	5 / 12	LEU A 284 LEU A 593 THR A 547 ILE A 549 ALA A 550	None None FAD  A 700 ( 4.6A) None FAD  A 700 ( 4.7A)	0.72A	21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	2r05	PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN (Homo sapiens)	5 / 12	LEU A  65 LEU A 124 ILE A 347 THR A 341 ALA A 128	None	0.93A	20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	3c6g	CYTOCHROME P450 2R1 (Homo sapiens)	5 / 12	ILE A 309 ALA A 310 GLU A 313 THR A 314 THR A 488	None HEM  A 601 (-3.3A) None HEM  A 601 (-3.4A) VD3  A 701 ( 4.6A)	0.60A	27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	3hlk	ACYL-COENZYME A THIOESTERASE 2, MITOCHONDRIAL (Homo sapiens)	5 / 12	LEU A  96 VAL A  94 ALA A 116 GLU A 121 ALA A  65	None	0.92A	23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	3ifq	PLAKOGLOBIN (Homo sapiens)	6 / 12	LEU A 497 LEU A 459 ILE A 485 ALA A 484 ALA A 445 ALA A 455	None	1.33A	23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	4bvx	EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 (Homo sapiens)	6 / 12	LEU B  61 VAL B  71 LEU B  10 THR B 114 ILE B 118 ALA B  48	None	1.27A	19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	4i6j	F-BOX/LRR-REPEAT PROTEIN 3 (Homo sapiens)	6 / 12	LEU B 144 PHE B 115 VAL B 117 ILE B 130 ALA B 126 ALA B 163	None	1.13A	21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	4kng	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 (Homo sapiens)	5 / 12	LEU A 236 LEU A 262 THR A 255 ILE A 253 ALA A 252	None	0.89A	22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	4ufs	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 (Homo sapiens)	5 / 12	LEU A 236 LEU A 262 THR A 255 ILE A 253 ALA A 252	None	0.84A	22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	5ei0	SERPIN A12 (Homo sapiens)	5 / 12	VAL A 384 LEU A 299 THR A 258 ILE A 259 GLU A 261	None	0.99A	22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	1gz4	NAD-DEPENDENT MALIC ENZYME (Homo sapiens)	4 / 5	LEU A 322 ALA A 289 VAL A 474 ILE A 526	None	0.95A	21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	1vec	ATP-DEPENDENT RNA HELICASE P54 (Homo sapiens)	4 / 5	LEU A 140 ALA A 156 VAL A 160 ILE A 159	None	0.89A	19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	1xnj	BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHETASE 1 (Homo sapiens)	4 / 5	LEU B 291 ALA B 353 VAL B 369 ILE B 366	None	0.98A	20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	1yrv	UBIQUITIN-CONJUGATIN G LIGASE MGC351130 (Homo sapiens)	4 / 5	LEU A  93 ALA A 111 VAL A  38 ILE A  40	None	0.89A	17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	1zkl	HIGH-AFFINITY CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 7A (Homo sapiens)	4 / 5	LEU A 243 ALA A 248 THR A 251 ILE A 201	None	0.89A	21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	2aw5	NADP-DEPENDENT MALIC ENZYME (Homo sapiens)	4 / 5	LEU A 312 ALA A 279 VAL A 461 ILE A 513	None	0.93A	21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	2iwz	3-OXOACYL-[ACYL-CARR IER-PROTEIN] SYNTHASE (Homo sapiens)	4 / 5	ALA A 396 THR A 399 VAL A 302 ILE A 456	None	0.79A	23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	2qjf	BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHETASE 1 (Homo sapiens)	4 / 5	LEU A 291 ALA A 353 VAL A 369 ILE A 366	None	0.94A	21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	2w3c	GENERAL VESICULAR TRANSPORT FACTOR P115 (Homo sapiens)	4 / 5	ALA A 327 THR A 331 VAL A 385 ILE A 334	None	0.76A	20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	3a7s	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 (Homo sapiens)	4 / 5	LEU A  55 ALA A  92 VAL A  32 ILE A 223	None	0.82A	21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	3p5b	LOW DENSITY LIPOPROTEIN RECEPTOR VARIANT (Homo sapiens)	4 / 5	LEU L 590 ALA L 500 THR L 513 ILE L 521	None	0.97A	21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	4bej	DYNAMIN 1-LIKE PROTEIN (Homo sapiens)	5 / 5	LEU A  67 ALA A 286 THR A 282 VAL A 258 ILE A 262	None	1.11A	23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	4o7d	GLUTAMINASE KIDNEY ISOFORM, MITOCHONDRIAL (Homo sapiens)	4 / 5	ALA A 338 THR A 342 VAL A 358 ILE A 345	None	0.98A	19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	4ov6	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 5	ALA B 363 THR B 339 VAL B 423 ILE B 424	None	0.94A	23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_A_CL6A502_1 (CYTOCHROME P-450)	4rwt	LEIOMODIN-2 (Homo sapiens)	4 / 5	LEU C 260 ALA C 255 VAL C 243 ILE C 248	None	0.99A	21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	1hvy	THYMIDYLATE SYNTHASE (Homo sapiens)	4 / 5	ALA A 238 THR A 241 VAL A 164 ILE A 165	None None BME  A1514 (-4.3A) None	0.91A	22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	1orf	GRANZYME A (Homo sapiens)	4 / 5	LEU A 108 ALA A  48 VAL A 118 ILE A 114	None	0.93A	19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	1vec	ATP-DEPENDENT RNA HELICASE P54 (Homo sapiens)	4 / 5	LEU A 140 ALA A 156 VAL A 160 ILE A 159	None	0.95A	19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	1xnj	BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHETASE 1 (Homo sapiens)	4 / 5	LEU B 291 ALA B 353 VAL B 369 ILE B 366	None	0.95A	20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	1yrv	UBIQUITIN-CONJUGATIN G LIGASE MGC351130 (Homo sapiens)	4 / 5	LEU A  93 ALA A 111 VAL A  38 ILE A  40	None	0.73A	17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	1zkl	HIGH-AFFINITY CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 7A (Homo sapiens)	4 / 5	LEU A 243 ALA A 248 THR A 251 ILE A 201	None	0.97A	21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	2aw5	NADP-DEPENDENT MALIC ENZYME (Homo sapiens)	4 / 5	LEU A 312 ALA A 279 VAL A 461 ILE A 513	None	0.97A	21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	2eyw	V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG ISOFORM A (Homo sapiens)	4 / 5	LEU A 159 ALA A 172 VAL A 184 ILE A 182	None	0.95A	11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	2iwz	3-OXOACYL-[ACYL-CARR IER-PROTEIN] SYNTHASE (Homo sapiens)	4 / 5	ALA A 396 THR A 399 VAL A 302 ILE A 456	None	0.86A	23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	2q5e	CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 2 (Homo sapiens)	4 / 5	LEU A 108 ALA A 167 VAL A 127 ILE A 129	None	0.81A	20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	2qjf	BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHETASE 1 (Homo sapiens)	4 / 5	LEU A 291 ALA A 353 VAL A 369 ILE A 366	None	0.88A	21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	2w3c	GENERAL VESICULAR TRANSPORT FACTOR P115 (Homo sapiens)	4 / 5	ALA A 327 THR A 331 VAL A 385 ILE A 334	None	0.77A	20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	2xsz	RUVB-LIKE 1 (Homo sapiens)	4 / 5	LEU A  38 ALA A  98 VAL A  80 ILE A 237	None	0.95A	22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	3gcw	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 5	ALA A 363 THR A 339 VAL A 423 ILE A 424	None	0.95A	23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE3_B_CL6B502_1 (CYTOCHROME P-450)	4bej	DYNAMIN 1-LIKE PROTEIN (Homo sapiens)	5 / 5	LEU A  67 ALA A 286 THR A 282 VAL A 258 ILE A 262	None	1.15A	23.48