POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	1fch	PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR (Homo sapiens)	5 / 12	ALA A 373 LEU A 372 ALA A 371 THR A 340 LEU A 486	None	1.18A	25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	2a1x	PHYTANOYL-COA DIOXYGENASE (Homo sapiens)	5 / 12	MET A 250 LEU A  67 PHE A  66 TYR A 133 THR A 194	None	1.19A	22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	2c0l	PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR (Homo sapiens)	5 / 12	ALA A 410 LEU A 409 ALA A 408 THR A 377 LEU A 523	None	1.21A	25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	2oew	PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN (Homo sapiens)	5 / 12	ALA A 131 LEU A 130 ALA A 129 PHE A 125 LEU A 187	None	1.20A	21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	3l5k	HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 1A (Homo sapiens)	5 / 12	ALA A 112 LEU A 111 ALA A 110 PHE A 134 PHE A 162	None	1.12A	21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	5fql	IDURONATE-2-SULFATAS E (Homo sapiens)	5 / 12	ALA A 222 LEU A  41 THR A 327 PHE A 219 LEU A 209	None	1.19A	23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	5i7q	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A,FKBP-TYPE 16 KDA PEPTIDYL-PROLYL CIS-TRANS ISOMERASE,PEPTIDYL-P ROLYL CIS-TRANS ISOMERASE FKBP1A (Escherichia coli; Homo sapiens)	5 / 12	LEU A 152 PHE A  48 LEU A  50 THR A  21 PRO A  16	None	1.20A	19.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	5mvd	DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL (Homo sapiens)	11 / 12	MET A  43 ALA A  55 HIS A  56 ALA A  59 PHE A  62 THR A  63 PHE A  98 TYR A 356 LEU A 359 THR A 360 PRO A 364	U91  A 403 (-4.1A) U91  A 403 (-3.6A) U91  A 403 (-4.1A) U91  A 403 (-3.3A) None U91  A 403 ( 4.9A) None FMN  A 401 ( 4.2A) U91  A 403 ( 4.3A) U91  A 403 (-3.9A) U91  A 403 ( 4.3A)	0.15A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	5mvd	DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL (Homo sapiens)	11 / 12	MET A  43 ALA A  55 HIS A  56 LEU A  58 ALA A  59 THR A  63 PHE A  98 TYR A 356 LEU A 359 THR A 360 PRO A 364	U91  A 403 (-4.1A) U91  A 403 (-3.6A) U91  A 403 (-4.1A) None U91  A 403 (-3.3A) U91  A 403 ( 4.9A) None FMN  A 401 ( 4.2A) U91  A 403 ( 4.3A) U91  A 403 (-3.9A) U91  A 403 ( 4.3A)	0.38A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	5npr	UDP-N-ACETYLGLUCOSAM INE--PEPTIDE N-ACETYLGLUCOSAMINYL TRANSFERASE 110 KDA SUBUNIT (Homo sapiens)	5 / 12	ALA A 946 HIS A 920 THR A 940 LEU A 916 THR A 914	None	1.01A	undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	5tce	DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL (Homo sapiens)	5 / 12	ALA A  23 HIS A  24 ALA A  27 PHE A  30 THR A  31	None	1.04A	97.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	5tce	DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL (Homo sapiens)	5 / 12	ALA A  23 HIS A  24 LEU A  26 ALA A  27 THR A  31	None	0.64A	97.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	5van	BETA-KLOTHO (Homo sapiens)	5 / 12	ALA A 718 HIS A 719 LEU A 721 ALA A 722 LEU A 641	None	0.79A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	5w21	KLOTHO (Homo sapiens)	5 / 12	ALA A 706 HIS A 707 LEU A 709 ALA A 710 LEU A 637	None	0.97A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_CE9A402_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	6bev	THIOSULFATE SULFURTRANSFERASE/RH ODANESE-LIKE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 12	ALA A  88 LEU A  91 ALA A  92 LEU A  75 PRO A  68	None	1.01A	undetectable