POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	1qk1	CREATINE KINASE, UBIQUITOUS MITOCHONDRIAL (Homo sapiens)	5 / 12	LEU A 312 LEU A 334 ARG A 336 LEU A 294 PHE A 303	None	1.16A	20.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	2ax9	ANDROGEN RECEPTOR (Homo sapiens)	10 / 12	LEU A 704 ASN A 705 LEU A 707 GLY A 708 GLN A 711 VAL A 746 ARG A 752 MET A 780 LEU A 880 PHE A 891	BHM  A   1 (-4.0A) BHM  A   1 (-3.6A) BHM  A   1 ( 4.2A) BHM  A   1 ( 3.8A) BHM  A   1 (-2.2A) BHM  A   1 (-3.6A) BHM  A   1 (-3.8A) BHM  A   1 ( 4.3A) None None	0.60A	99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	2ax9	ANDROGEN RECEPTOR (Homo sapiens)	7 / 12	LEU A 707 GLY A 708 GLN A 711 VAL A 746 ARG A 752 LEU A 880 MET A 895	BHM  A   1 ( 4.2A) BHM  A   1 ( 3.8A) BHM  A   1 (-2.2A) BHM  A   1 (-3.6A) BHM  A   1 (-3.8A) None None	0.96A	99.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	2mgs	C-X-C MOTIF CHEMOKINE 5 (Homo sapiens)	5 / 12	LEU A  63 GLY A  21 GLN A  20 ALA A  46 LEU A  30	None	1.06A	20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	2vxo	GMP SYNTHASE [GLUTAMINE-HYDROLYZI NG] (Homo sapiens)	5 / 12	LEU A 256 LEU A 260 GLN A 264 VAL A 362 LEU A 243	None	1.13A	15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	3hlk	ACYL-COENZYME A THIOESTERASE 2, MITOCHONDRIAL (Homo sapiens)	5 / 12	LEU A 299 GLY A 292 VAL A 320 ALA A 304 LEU A 307	None	1.11A	19.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	3kba	PROGESTERONE RECEPTOR (Homo sapiens)	5 / 12	ASN A 719 GLY A 722 VAL A 760 PHE A 905 MET A 909	WOW  A   1 (-3.3A) WOW  A   1 ( 4.3A) WOW  A   1 (-4.1A) WOW  A   1 (-4.6A) None	0.87A	55.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	3kba	PROGESTERONE RECEPTOR (Homo sapiens)	7 / 12	LEU A 718 ASN A 719 LEU A 721 GLY A 722 VAL A 760 ARG A 766 PHE A 905	WOW  A   1 (-4.2A) WOW  A   1 (-3.3A) WOW  A   1 ( 4.3A) WOW  A   1 ( 4.3A) WOW  A   1 (-4.1A) WOW  A   1 (-3.8A) WOW  A   1 (-4.6A)	0.44A	55.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	3kba	PROGESTERONE RECEPTOR (Homo sapiens)	6 / 12	LEU A 718 LEU A 721 GLY A 722 GLN A 725 VAL A 760 ARG A 766	WOW  A   1 (-4.2A) WOW  A   1 ( 4.3A) WOW  A   1 ( 4.3A) WOW  A   1 ( 4.1A) WOW  A   1 (-4.1A) WOW  A   1 (-3.8A)	0.80A	55.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	4kf6	GLYCOLIPID TRANSFER PROTEIN DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 12	LEU A  43 ASN A  44 LEU A  46 GLY A  47 VAL A 158	None	1.13A	21.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	4p6w	GLUCOCORTICOID RECEPTOR (Homo sapiens)	7 / 12	LEU A 563 ASN A 564 LEU A 566 GLY A 567 GLN A 570 ARG A 611 PHE A 749	MOF  A 801 (-3.9A) MOF  A 801 (-3.0A) MOF  A 801 ( 4.6A) MOF  A 801 (-3.4A) MOF  A 801 (-2.9A) MOF  A 801 (-4.2A) MOF  A 801 (-4.4A)	0.78A	50.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	4udb	MINERALOCORTICOID RECEPTOR (Homo sapiens)	6 / 12	LEU A 769 ASN A 770 LEU A 772 GLN A 776 ARG A 817 PHE A 956	CV7  A1987 (-4.1A) CV7  A1987 (-3.1A) CV7  A1987 ( 4.5A) CV7  A1987 (-3.0A) CV7  A1987 (-3.7A) CV7  A1987 ( 4.7A)	0.74A	48.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	5mju	EXCITATORY AMINO ACID TRANSPORTER 1,NEUTRAL AMINO ACID TRANSPORTER B(0),EXCITATORY AMINO ACID TRANSPORTER 1 (Homo sapiens)	5 / 12	ASN A 463 LEU A 465 GLY A 466 VAL A 312 ALA A 383	7O9  A 602 (-3.8A) None None None None	0.87A	18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	5mov	CASEIN KINASE II SUBUNIT ALPHA (Homo sapiens)	5 / 12	LEU A 128 VAL A 327 ARG A 169 ALA A 297 LEU A 301	None	1.12A	22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	5mwp	MINERALOCORTICOID RECEPTOR (Homo sapiens)	7 / 12	LEU A 769 ASN A 770 LEU A 772 GLN A 776 ARG A 817 MET A 845 PHE A 956	ECV  A1101 (-4.7A) ECV  A1101 (-3.1A) ECV  A1101 ( 3.9A) ECV  A1101 (-2.9A) ECV  A1101 (-4.0A) ECV  A1101 (-4.0A) ECV  A1101 ( 4.7A)	0.66A	18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	5wc2	PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG (Homo sapiens)	5 / 12	LEU A 373 ASN A 374 LEU A 372 VAL A 418 ALA A 324	None	1.15A	19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	1ich	TUMOR NECROSIS FACTOR RECEPTOR-1 (Homo sapiens)	4 / 6	LEU A 405 TRP A 342 MET A 374 LEU A 330	None	1.34A	18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	1u59	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	4 / 6	LEU A 337 MET A 383 MET A 384 LEU A 371	None	1.47A	22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	1z6t	APOPTOTIC PROTEASE ACTIVATING FACTOR 1 (Homo sapiens)	4 / 6	LEU A 195 TRP A 149 MET A 231 LEU A 240	None	1.39A	18.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	2ax9	ANDROGEN RECEPTOR (Homo sapiens)	4 / 6	LEU A 880 TRP A 741 MET A 742 MET A 787	None None BHM  A   1 ( 4.0A) BHM  A   1 (-3.6A)	1.29A	99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	2ax9	ANDROGEN RECEPTOR (Homo sapiens)	4 / 6	LEU A 880 TRP A 741 MET A 745 MET A 787	None None BHM  A   1 (-3.9A) BHM  A   1 (-3.6A)	1.42A	99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	2ax9	ANDROGEN RECEPTOR (Homo sapiens)	4 / 6	TRP A 741 MET A 742 MET A 787 LEU A 873	None BHM  A   1 ( 4.0A) BHM  A   1 (-3.6A) BHM  A   1 (-4.4A)	0.30A	99.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	2d9q	GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR (Homo sapiens)	4 / 6	MET B 110 MET B 199 MET B 176 LEU B 117	None	1.36A	19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	3a6p	EXPORTIN-5 (Homo sapiens)	4 / 6	TRP A 128 MET A 135 MET A  95 LEU A 139	None	1.24A	12.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	3kba	PROGESTERONE RECEPTOR (Homo sapiens)	4 / 6	LEU A 715 TRP A 755 MET A 756 LEU A 887	WOW  A   1 (-3.9A) None WOW  A   1 ( 4.1A) WOW  A   1 (-4.0A)	0.85A	55.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	3kba	PROGESTERONE RECEPTOR (Homo sapiens)	4 / 6	TRP A 755 MET A 756 MET A 801 LEU A 887	None WOW  A   1 ( 4.1A) WOW  A   1 (-4.2A) WOW  A   1 (-4.0A)	0.82A	55.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	3n3z	HIGH AFFINITY CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 9A (Homo sapiens)	4 / 6	LEU A 205 MET A 263 MET A 218 LEU A 196	None	1.38A	21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	3ntc	FAB HEAVY CHAIN (Homo sapiens; Mus musculus)	4 / 6	TRP H  36 MET H  80 MET H  69 LEU H  82	None	1.40A	18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	3pbl	D(3) DOPAMINE RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	4 / 6	TRP A1138 MET A1102 MET A1106 LEU A1099	None	1.29A	19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	3qi3	HIGH AFFINITY CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 9A (Homo sapiens)	4 / 6	LEU A 205 MET A 263 MET A 218 LEU A 196	None	1.47A	18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	3sqo	J16 HEAVY CHAIN (Homo sapiens)	4 / 6	TRP H  36 MET H  80 MET H  69 LEU H  82	None	1.47A	19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	3t0o	RIBONUCLEASE T2 (Homo sapiens)	4 / 6	LEU A 128 TRP A  97 MET A  93 LEU A  89	None	1.43A	20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	4iml	CROSSED HEAVY CHAIN (VH-CKAPPA) (Homo sapiens)	4 / 6	TRP H  36 MET H  81 MET H  70 LEU H  83	None	1.46A	19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	4m6t	RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG, LINKER, RNA POLYMERASE-ASSOCIATE D PROTEIN LEO1 (Homo sapiens)	4 / 6	MET A  53 MET A  80 MET A  85 LEU A 103	None	1.15A	19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	4u1r	ATP-DEPENDENT 6-PHOSPHOFRUCTOKINAS E, PLATELET TYPE (Homo sapiens)	4 / 6	LEU A 483 MET A 532 MET A 495 LEU A 503	None	1.32A	15.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	4udb	MINERALOCORTICOID RECEPTOR (Homo sapiens)	4 / 6	LEU A 766 TRP A 806 MET A 807 LEU A 938	CV7  A1987 (-3.6A) None CV7  A1987 ( 3.9A) CV7  A1987 ( 3.9A)	1.35A	48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	4udb	MINERALOCORTICOID RECEPTOR (Homo sapiens)	4 / 6	TRP A 806 MET A 807 MET A 852 LEU A 938	None CV7  A1987 ( 3.9A) CV7  A1987 ( 3.7A) CV7  A1987 ( 3.9A)	1.25A	48.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	5f0k	VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35 (Homo sapiens)	4 / 6	LEU A  53 MET A 190 MET A 197 LEU A 216	None	1.45A	19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	5mwp	MINERALOCORTICOID RECEPTOR (Homo sapiens)	4 / 6	TRP A 806 MET A 807 MET A 852 LEU A 938	None ECV  A1101 (-3.6A) ECV  A1101 (-3.7A) ECV  A1101 ( 4.3A)	1.31A	18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	5nug	CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 (Homo sapiens)	4 / 6	LEU A3892 MET A4343 MET A4346 LEU A3909	None	1.43A	4.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	5ob5	FAB HEAVY CHAIN (Homo sapiens)	4 / 6	TRP H  36 MET H  81 MET H  70 LEU H  83	None	1.47A	18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	5t9j	FLAP ENDONUCLEASE GEN HOMOLOG 1 (Homo sapiens)	4 / 6	LEU A 378 TRP A 366 MET A 364 LEU A  53	None	1.31A	18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	5tqa	DH270.6 FAB HEAVY CHAIN (Homo sapiens)	4 / 6	TRP H  36 MET H  81 MET H  70 LEU H  83	None	1.44A	17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	5trp	DH272 FAB HEAVY CHAIN (Homo sapiens)	4 / 6	TRP H  36 MET H  79 MET H  70 LEU H  81	None	1.41A	17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	5w21	KLOTHO (Homo sapiens)	4 / 6	LEU A 651 MET A 687 MET A 695 LEU A 703	None	1.30A	15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	6co1	TUDOR-INTERACTING REPAIR REGULATOR PROTEIN (Homo sapiens)	4 / 6	LEU A  51 MET A 182 MET A 183 LEU A 180	None	1.31A	15.83