POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A206_1 (UNCHARACTERIZED PROTEIN)	2jam	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE 1G (Homo sapiens)	5 / 10	PHE A 300 PRO A 147 ASN A 149 PHE A 107 LEU A 213	None	1.44A	20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A206_1 (UNCHARACTERIZED PROTEIN)	2l29	INSULIN-LIKE GROWTH FACTOR 2 RECEPTOR VARIANT (Homo sapiens)	5 / 10	TYR A1549 GLY A1564 ASN A1556 PHE A1638 LEU A1636	None	1.32A	21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A206_1 (UNCHARACTERIZED PROTEIN)	2l3d	LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A (Homo sapiens)	5 / 10	PHE A  25 GLY A  31 PHE A  39 ARG A  80 LEU A  77	None	1.40A	20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A206_1 (UNCHARACTERIZED PROTEIN)	5fn4	NICASTRIN (Homo sapiens)	5 / 10	ARG A 117 TYR A  94 GLY A  89 PHE A 210 LEU A 212	None	1.10A	12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	2aw0	MENKES COPPER-TRANSPORTING ATPASE (Homo sapiens)	3 / 3	GLY A  43 GLU A   4 THR A   5	None	0.37A	18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	2www	METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL (Homo sapiens)	3 / 3	GLY A 150 GLU A 242 THR A 243	None	0.57A	18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	2z5d	UBIQUITIN-CONJUGATIN G ENZYME E2 H (Homo sapiens)	3 / 3	GLY A  67 GLU A 170 THR A 169	None	0.46A	18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	3bn3	INTERCELLULAR ADHESION MOLECULE 5 (Homo sapiens)	3 / 3	GLY B  81 GLU B  63 THR B  64	None	0.55A	21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	3ckk	TRNA (GUANINE-N(7)-)-METH YLTRANSFERASE (Homo sapiens)	3 / 3	GLY A  56 GLU A 209 THR A 208	SAM  A 301 (-3.5A) None SAM  A 301 (-2.8A)	0.57A	19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	3ctz	XAA-PRO AMINOPEPTIDASE 1 (Homo sapiens)	3 / 3	GLY A 525 GLU A 523 THR A 487	None MN  A 624 ( 2.5A) None	0.47A	13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	3iwp	COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG (Homo sapiens)	3 / 3	GLY A 113 GLU A 167 THR A 143	None	0.54A	19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	3ljb	INTERFERON-INDUCED GTP-BINDING PROTEIN MX1 (Homo sapiens)	3 / 3	GLY A 397 GLU A 394 THR A 395	None	0.55A	17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	3u7u	NEUREGULIN 1 RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	3 / 3	GLY G  44 GLU A   8 THR A   7	None	0.59A	15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	4oib	INTERCELLULAR ADHESION MOLECULE 5 (Homo sapiens)	3 / 3	GLY A  81 GLU A  63 THR A  64	None	0.52A	19.84