POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	1itu	RENAL DIPEPTIDASE (Homo sapiens)	5 / 10	GLY A 286 VAL A 249 LEU A 271 LEU A 308 TYR A 305	None	1.21A	24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	1lhu	SEX HORMONE-BINDING GLOBULIN (Homo sapiens)	5 / 10	GLY A 145 VAL A  54 TRP A  66 LEU A 157 LEU A 153	None	1.31A	20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	2ee7	SPERM FLAGELLAR PROTEIN 1 (Homo sapiens)	5 / 10	GLY A 105 VAL A 107 LEU A  36 SER A  37 TYR A  21	None	1.25A	15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	2iwi	SERINE/THREONINE-PRO TEIN KINASE PIM-2 (Homo sapiens)	5 / 10	GLY A 145 VAL A 147 LEU A 224 LEU A 277 ALA A 150	None	1.09A	23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	3k2m	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	5 / 10	VAL A 151 LEU A 169 LEU A 160 SER A 183 ALA A 155	None	1.37A	15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	4eih	ABELSON TYROSINE-PROTEIN KINASE 2 (Homo sapiens)	5 / 10	VAL A 178 LEU A 196 LEU A 187 SER A 210 ALA A 182	None	1.24A	15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	4idt	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 (Homo sapiens)	5 / 10	GLY A 633 LEU A 496 LEU A 500 SER A 582 ALA A 629	None	1.42A	23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	4l8t	UNCONVENTIONAL MYOSIN-VC (Homo sapiens)	5 / 10	VAL A1691 TRP A1639 LEU A1670 LEU A1640 ALA A1651	None	1.06A	20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	4wmy	INTELECTIN-1 (Homo sapiens)	5 / 10	TRP A 117 LEU A 147 LEU A 183 TYR A 187 ALA A 252	None	1.40A	20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	4wmy	INTELECTIN-1 (Homo sapiens)	5 / 10	VAL A 236 TRP A 117 LEU A 147 LEU A 183 TYR A 187	None	1.25A	20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	5anb	ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 10	GLY K1035 VAL K 665 LEU K1052 TYR K 985 LEU K1028	None	1.35A	16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	5ons	MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1 DENSITY-REGULATED PROTEIN (Homo sapiens; Homo sapiens)	5 / 10	VAL A  97 LEU A 143 LEU A 106 TYR B  46 ALA A 101	None	1.35A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	5zya	SPLICING FACTOR 3B SUBUNIT 1 (Homo sapiens)	5 / 10	VAL C 936 LEU C 974 LEU C 978 TYR C 981 ALA C 951	None	1.26A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBF_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	2ro1	TRANSCRIPTION INTERMEDIARY FACTOR 1-BETA (Homo sapiens)	5 / 9	VAL A 765 LEU A 708 LEU A 747 ARG A 746 ALA A 762	None	1.13A	23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBF_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	4l8t	UNCONVENTIONAL MYOSIN-VC (Homo sapiens)	5 / 9	VAL A1691 TRP A1639 LEU A1670 LEU A1640 ALA A1651	None	1.08A	20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	1w9c	CRM1 PROTEIN (Homo sapiens)	4 / 6	LEU A 780 VAL A 784 LEU A 785 VAL A 800	None	0.96A	19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	2iip	NICOTINAMIDE N-METHYLTRANSFERASE (Homo sapiens)	5 / 6	LEU A 131 ARG A 132 VAL A 135 LEU A  98 VAL A  83	None	1.29A	27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	2nzi	TITIN (Homo sapiens)	4 / 6	LEU A 214 VAL A 255 LEU A 258 VAL A 245	None	0.85A	21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	2v9k	UNCHARACTERIZED PROTEIN FLJ32312 (Homo sapiens)	4 / 6	ARG A 176 VAL A 163 LEU A 174 VAL A  11	None	0.89A	14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	2wul	GLUTAREDOXIN RELATED PROTEIN 5 (Homo sapiens)	4 / 6	LEU A 125 VAL A 112 LEU A 114 VAL A  56	None	0.98A	26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	3d3w	L-XYLULOSE REDUCTASE (Homo sapiens)	4 / 6	LEU B  11 VAL B  37 LEU B  61 VAL B  57	None None NAP  B1245 (-3.8A) None	0.94A	24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	3hd6	AMMONIUM TRANSPORTER RH TYPE C (Homo sapiens)	4 / 6	LEU A 151 VAL A 146 LEU A 416 VAL A 142	None	0.95A	14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	3mcf	DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 3-ALPHA (Homo sapiens)	4 / 6	LEU A  35 VAL A  33 LEU A  23 VAL A 122	None	0.87A	24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	3mjg	PLATELET-DERIVED GROWTH FACTOR SUBUNIT B (Homo sapiens)	4 / 6	LEU A  91 VAL A  89 LEU A  29 VAL A  72	None	0.79A	22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	3toj	SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 (Homo sapiens)	4 / 6	LEU A 298 ARG A 294 VAL A 307 LEU A 289	None	0.95A	24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	4a5w	COMPLEMENT C5 (Homo sapiens)	4 / 6	LEU A 602 VAL A 600 LEU A 571 VAL A 780	None	0.89A	8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	4go6	HCF C-TERMINAL CHAIN 1 (Homo sapiens)	4 / 6	LEU B1908 VAL B1961 LEU B1966 VAL B1951	None	0.85A	26.41