POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F94_F_BFQF9001_1 (FARNESYL DIPHOSPHATE SYNTHASE)	2q80	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Homo sapiens)	6 / 12	LEU A  61 ARG A  73 LYS A 151 GLN A 185 ASP A 188 LYS A 202	None GRG  A 500 (-2.9A) GRG  A 500 (-2.8A) GRG  A 500 (-3.2A) GRG  A 500 (-3.5A) GRG  A 500 ( 2.6A)	1.33A	26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F94_F_BFQF9001_1 (FARNESYL DIPHOSPHATE SYNTHASE)	2q80	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Homo sapiens)	8 / 12	LEU A  61 ASP A  64 ASP A  68 ARG A  73 GLN A 126 LYS A 151 GLN A 185 ASP A 188	None GRG  A 500 (-2.4A) MG  A 400 (-2.6A) GRG  A 500 (-2.9A) GRG  A 500 ( 3.5A) GRG  A 500 (-2.8A) GRG  A 500 (-3.2A) GRG  A 500 (-3.5A)	0.82A	26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F94_F_BFQF9001_1 (FARNESYL DIPHOSPHATE SYNTHASE)	2q80	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Homo sapiens)	7 / 12	LEU A  61 ASP A  64 ASP A  68 ARG A  73 GLN A 126 LYS A 151 THR A 152	None GRG  A 500 (-2.4A) MG  A 400 (-2.6A) GRG  A 500 (-2.9A) GRG  A 500 ( 3.5A) GRG  A 500 (-2.8A) GRG  A 500 ( 4.6A)	0.89A	26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F94_F_BFQF9001_1 (FARNESYL DIPHOSPHATE SYNTHASE)	2q80	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Homo sapiens)	6 / 12	LEU A  61 ASP A  64 ASP A  68 ARG A  73 THR A 152 GLN A 126	None GRG  A 500 (-2.4A) MG  A 400 (-2.6A) GRG  A 500 (-2.9A) GRG  A 500 ( 4.6A) GRG  A 500 ( 3.5A)	1.41A	26.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2F94_F_BFQF9001_1 (FARNESYL DIPHOSPHATE SYNTHASE)	4p0v	FARNESYL PYROPHOSPHATE SYNTHASE (Homo sapiens)	11 / 12	LEU A 100 ASP A 103 ASP A 107 ARG A 112 THR A 167 GLN A 171 LYS A 200 THR A 201 GLN A 240 ASP A 243 LYS A 257	None MG  A 405 (-2.5A) MG  A 405 (-2.4A) ZOL  A 401 ( 2.7A) None ZOL  A 401 ( 3.8A) ZOL  A 401 (-2.7A) ZOL  A 401 (-3.7A) ZOL  A 401 (-3.5A) MG  A 404 (-2.8A) 1WO  A 402 ( 2.8A)	0.56A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2F94_F_BFQF9001_1 (FARNESYL DIPHOSPHATE SYNTHASE)	4p0v	FARNESYL PYROPHOSPHATE SYNTHASE (Homo sapiens)	11 / 12	LEU A 100 ASP A 103 ASP A 107 ARG A 112 THR A 167 LYS A 200 THR A 201 TYR A 204 GLN A 240 ASP A 243 LYS A 257	None MG  A 405 (-2.5A) MG  A 405 (-2.4A) ZOL  A 401 ( 2.7A) None ZOL  A 401 (-2.7A) ZOL  A 401 (-3.7A) None ZOL  A 401 (-3.5A) MG  A 404 (-2.8A) 1WO  A 402 ( 2.8A)	0.27A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_A_BFQA1297_1 (GERANYLTRANSTRANSFER ASE)	1jeq	KU70 (Homo sapiens)	4 / 8	LEU A 420 ASP A 421 ASP A 422 LYS A 245	None	1.06A	19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_A_BFQA1297_1 (GERANYLTRANSTRANSFER ASE)	1jeq	KU70 (Homo sapiens)	4 / 8	SER A  37 LEU A  82 ASP A  81 ASP A  79	None	0.78A	19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_A_BFQA1297_1 (GERANYLTRANSTRANSFER ASE)	2q80	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Homo sapiens)	7 / 8	SER A  60 LEU A  61 ASP A  64 ASP A  68 ARG A  73 GLN A 126 LYS A 151	GRG  A 500 ( 4.2A) None GRG  A 500 (-2.4A) MG  A 400 (-2.6A) GRG  A 500 (-2.9A) GRG  A 500 ( 3.5A) GRG  A 500 (-2.8A)	0.73A	24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_A_BFQA1297_1 (GERANYLTRANSTRANSFER ASE)	2wmo	DEDICATOR OF CYTOKINESIS PROTEIN 9 (Homo sapiens)	4 / 8	LEU A 335 MET A 408 GLN A 405 LYS A 409	None	1.04A	21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_A_BFQA1297_1 (GERANYLTRANSTRANSFER ASE)	4p0v	FARNESYL PYROPHOSPHATE SYNTHASE (Homo sapiens)	6 / 8	LEU A 100 ASP A 103 ASP A 107 ARG A 112 GLN A 171 LYS A 200	None MG  A 405 (-2.5A) MG  A 405 (-2.4A) ZOL  A 401 ( 2.7A) ZOL  A 401 ( 3.8A) ZOL  A 401 (-2.7A)	0.68A	28.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_A_BFQA1297_1 (GERANYLTRANSTRANSFER ASE)	5iaa	UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 5 (Homo sapiens)	4 / 8	SER C  12 LEU C  10 ASP C  13 GLN A 289	None	0.95A	10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_A_BFQA1297_1 (GERANYLTRANSTRANSFER ASE)	5oik	TRANSCRIPTION ELONGATION FACTOR SPT5 (Homo sapiens)	4 / 8	SER Z 504 LEU Z 506 ASP Z 505 LYS Z 479	None	0.93A	13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_A_BFQA1297_1 (GERANYLTRANSTRANSFER ASE)	5w6m	HISTIDINE--TRNA LIGASE, CYTOPLASMIC (Homo sapiens)	4 / 8	SER A 323 LEU A 324 ASP A 239 LYS A 243	None	1.01A	14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_A_BFQA1298_1 (GERANYLTRANSTRANSFER ASE)	2egc	SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A (Homo sapiens)	4 / 4	ILE A  49 PHE A  28 GLN A  29 ASP A  18	None	1.22A	15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_B_BFQB1294_1 (GERANYLTRANSTRANSFER ASE)	2q80	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Homo sapiens)	8 / 9	SER A  60 LEU A  61 ASP A  64 ASP A  68 ARG A  73 GLN A 126 LYS A 151 THR A 152	GRG  A 500 ( 4.2A) None GRG  A 500 (-2.4A) MG  A 400 (-2.6A) GRG  A 500 (-2.9A) GRG  A 500 ( 3.5A) GRG  A 500 (-2.8A) GRG  A 500 ( 4.6A)	0.65A	24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_B_BFQB1294_1 (GERANYLTRANSTRANSFER ASE)	4p0v	FARNESYL PYROPHOSPHATE SYNTHASE (Homo sapiens)	7 / 9	LEU A 100 ASP A 103 ASP A 107 ARG A 112 GLN A 171 LYS A 200 THR A 201	None MG  A 405 (-2.5A) MG  A 405 (-2.4A) ZOL  A 401 ( 2.7A) ZOL  A 401 ( 3.8A) ZOL  A 401 (-2.7A) ZOL  A 401 (-3.7A)	0.59A	28.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UMJ_B_BFQB1294_1 (GERANYLTRANSTRANSFER ASE)	4p0v	FARNESYL PYROPHOSPHATE SYNTHASE (Homo sapiens)	5 / 9	LEU A 100 ASP A 103 ASP A 107 ARG A 112 THR A 167	None MG  A 405 (-2.5A) MG  A 405 (-2.4A) ZOL  A 401 ( 2.7A) None	1.24A	28.41