POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1k2p	TYROSINE-PROTEIN KINASE BTK (Homo sapiens)	7 / 12	LEU A 408 VAL A 416 ALA A 428 LYS A 430 VAL A 458 GLY A 480 LEU A 528	None	0.76A	33.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1rjb	FL CYTOKINE RECEPTOR (Homo sapiens)	9 / 12	LEU A 616 VAL A 624 ALA A 642 LYS A 644 GLU A 661 VAL A 675 GLY A 697 LEU A 818 CYH A 828	None	0.53A	48.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1t46	HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG (Homo sapiens)	10 / 12	LEU A 595 VAL A 603 ALA A 621 LYS A 623 GLU A 640 VAL A 654 GLY A 676 LEU A 799 CYH A 809 PHE A 811	STI  A   3 ( 3.8A) STI  A   3 ( 4.6A) STI  A   3 (-3.5A) STI  A   3 (-3.7A) STI  A   3 (-3.6A) STI  A   3 (-4.3A) STI  A   3 ( 3.8A) STI  A   3 (-4.4A) STI  A   3 (-4.5A) STI  A   3 (-3.6A)	0.50A	53.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1u59	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	7 / 12	LEU A 344 VAL A 352 ALA A 367 GLU A 386 VAL A 399 GLY A 420 LEU A 468	STU  A 100 (-3.8A) STU  A 100 (-4.8A) STU  A 100 (-3.2A) None None STU  A 100 (-3.5A) STU  A 100 (-4.5A)	0.45A	32.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1zlt	SERINE/THREONINE-PRO TEIN KINASE CHK1 (Homo sapiens)	8 / 12	LEU A  15 VAL A  23 ALA A  36 LYS A  38 GLU A  55 VAL A  68 GLY A  90 LEU A 137	HYM  A 400 (-4.2A) HYM  A 400 (-4.3A) HYM  A 400 (-3.5A) HYM  A 400 (-3.2A) None HYM  A 400 (-4.8A) None HYM  A 400 (-4.5A)	0.49A	26.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2buj	SERINE/THREONINE-PRO TEIN KINASE 16 (Homo sapiens)	8 / 12	LEU A  26 VAL A  34 ALA A  47 LYS A  49 GLU A  65 PHE A 100 GLY A 104 LEU A 155	STU  A1301 (-4.2A) STU  A1301 (-4.8A) STU  A1301 (-3.6A) STU  A1301 ( 4.0A) None STU  A1301 (-4.5A) STU  A1301 ( 4.0A) STU  A1301 ( 4.8A)	0.84A	23.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	8 / 12	LEU X  17 VAL X  25 ALA X  37 LYS X  39 GLU X  54 VAL X  67 GLY X  88 LEU X 137	STU  X 902 (-3.8A) STU  X 902 ( 4.8A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) STU  X 902 ( 4.4A) None STU  X 902 (-3.5A) STU  X 902 (-4.4A)	0.57A	34.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2eu9	DUAL SPECIFICITY PROTEIN KINASE CLK3 (Homo sapiens)	7 / 12	LEU A 162 VAL A 170 ALA A 184 LYS A 186 GLU A 201 VAL A 220 LEU A 290	None	0.74A	24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	7 / 12	LEU A 273 VAL A 281 ALA A 293 VAL A 323 PHE A 340 GLY A 344 LEU A 393	QUE  A   1 (-3.9A) QUE  A   1 ( 4.8A) QUE  A   1 (-3.5A) None QUE  A   1 (-4.2A) QUE  A   1 (-3.0A) QUE  A   1 (-4.4A)	0.76A	28.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	9 / 12	LEU A 251 VAL A 259 ALA A 271 LYS A 273 GLU A 288 VAL A 301 PHE A 318 GLY A 322 LEU A 371	1BM  A 499 ( 3.7A) 1BM  A 499 ( 4.8A) 1BM  A 499 (-3.6A) 1BM  A 499 (-3.8A) 1BM  A 499 (-3.2A) None 1BM  A 499 (-4.1A) 1BM  A 499 (-3.5A) 1BM  A 499 (-4.4A)	0.94A	39.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2hw6	MAP KINASE-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 1 (Homo sapiens)	7 / 12	LEU A  55 VAL A  63 ALA A  76 LYS A  78 GLY A 130 LEU A 177 CYH A 190	None	0.53A	26.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	10 / 12	LEU A 248 VAL A 256 ALA A 269 LYS A 271 GLU A 286 VAL A 299 PHE A 317 GLY A 321 LEU A 370 PHE A 382	GIN  A 600 ( 4.6A) GIN  A 600 ( 4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-3.6A) GIN  A 600 (-3.6A) GIN  A 600 (-4.6A) GIN  A 600 (-4.3A) None GIN  A 600 (-4.7A) GIN  A 600 (-4.0A)	0.41A	37.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2ogv	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR PRECURSOR (Homo sapiens)	8 / 12	LEU A 588 VAL A 596 ALA A 614 LYS A 616 GLU A 633 VAL A 647 GLY A 669 LEU A 785	None	0.58A	50.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2psq	FIBROBLAST GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	LEU A 487 VAL A 495 ALA A 515 GLU A 534 VAL A 564 GLY A 570 LEU A 633	None	0.51A	47.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2qlu	ACTIVIN RECEPTOR TYPE IIB (Homo sapiens)	7 / 12	VAL A 204 ALA A 215 LYS A 217 GLU A 230 PHE A 267 GLY A 271 LEU A 328	ADE  A 488 ( 4.9A) ADE  A 488 (-3.2A) None None ADE  A 488 (-4.3A) ADE  A 488 ( 4.1A) ADE  A 488 (-4.4A)	0.76A	25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	8 / 12	LEU A  68 VAL A  76 ALA A  92 LYS A  94 VAL A 125 PHE A 143 GLY A 147 LEU A 194	STU  A   1 (-3.8A) None STU  A   1 (-3.3A) STU  A   1 (-2.8A) None STU  A   1 (-4.6A) STU  A   1 ( 3.9A) STU  A   1 (-4.6A)	0.45A	28.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3b2t	FIBROBLAST GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	LEU A 487 VAL A 495 ALA A 515 LYS A 517 VAL A 564 GLY A 570 LEU A 633	M33  A1996 (-4.0A) M33  A1996 ( 4.7A) M33  A1996 (-3.3A) M33  A1996 ( 4.5A) None M33  A1996 ( 4.8A) M33  A1996 (-4.5A)	0.48A	54.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3c4f	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	7 / 12	LEU A 484 VAL A 492 ALA A 512 GLU A 531 VAL A 561 GLY A 567 LEU A 630	C4F  A   1 ( 3.9A) None C4F  A   1 (-3.3A) None C4F  A   1 ( 4.8A) None C4F  A   1 (-4.6A)	0.57A	54.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	7 / 12	VAL A 209 ALA A 220 LYS A 222 GLU A 236 VAL A 249 GLY A 272 LEU A 321	None	0.54A	35.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3hng	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	11 / 12	LEU A 833 VAL A 841 ALA A 859 LYS A 861 GLU A 878 VAL A 892 VAL A 909 GLY A 915 LEU A1029 CYH A1039 PHE A1041	8ST  A2001 ( 4.7A) 8ST  A2001 ( 4.6A) 8ST  A2001 ( 3.8A) 8ST  A2001 (-4.0A) 8ST  A2001 (-3.7A) 8ST  A2001 ( 4.7A) 8ST  A2001 (-4.1A) None None 8ST  A2001 (-4.2A) 8ST  A2001 ( 3.7A)	0.47A	67.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3mvj	CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	8 / 12	LEU A  49 VAL A  57 ALA A  70 LYS A  72 GLU A  91 VAL A 104 GLY A 126 LEU A 173	XFE  A 351 (-4.2A) XFE  A 351 ( 4.5A) XFE  A 351 (-3.2A) None None None None XFE  A 351 (-4.6A)	0.65A	23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3nuu	PKB-LIKE (Homo sapiens)	7 / 12	LEU A  88 VAL A  96 ALA A 109 LYS A 111 GLU A 130 GLY A 165 LEU A 212	JOZ  A 361 (-4.1A) JOZ  A 361 ( 4.7A) JOZ  A 361 (-3.4A) SO4  A   5 (-2.8A) SO4  A   5 (-3.1A) None None	0.49A	25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3nuu	PKB-LIKE (Homo sapiens)	7 / 12	LEU A  88 VAL A  96 ALA A 109 LYS A 111 GLU A 130 VAL A 143 GLY A 165	JOZ  A 361 (-4.1A) JOZ  A 361 ( 4.7A) JOZ  A 361 (-3.4A) SO4  A   5 (-2.8A) SO4  A   5 (-3.1A) None None	0.60A	25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	8 / 12	LEU A 192 VAL A 200 ALA A 213 LYS A 215 GLU A 234 VAL A 247 GLY A 269 LEU A 318	AMP  A 577 ( 4.3A) AMP  A 577 (-4.3A) AMP  A 577 (-3.4A) AMP  A 577 (-2.8A) None None None AMP  A 577 (-4.8A)	0.80A	22.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3tt0	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	8 / 12	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLU A 531 VAL A 561 GLY A 567 LEU A 630	07J  A   1 ( 4.3A) 07J  A   1 (-4.0A) 07J  A   1 (-3.5A) 07J  A   1 (-4.5A) 07J  A   1 (-3.8A) 07J  A   1 (-4.7A) 07J  A   1 (-3.7A) 07J  A   1 ( 4.4A)	0.57A	48.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	8 / 12	LEU A 361 VAL A 369 ALA A 382 LYS A 384 GLU A 403 PHE A 435 GLY A 439 LEU A 486	07U  A   1 ( 4.8A) 07U  A   1 (-4.8A) 07U  A   1 (-3.3A) 07U  A   1 (-3.0A) 07U  A   1 ( 4.8A) None None 07U  A   1 (-4.3A)	0.72A	23.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3vid	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	10 / 12	LEU A 840 VAL A 848 ALA A 866 GLU A 885 VAL A 899 VAL A 916 PHE A 918 GLY A 922 LEU A1035 CYH A1045	4TT  A2001 ( 4.0A) 4TT  A2001 ( 4.5A) 4TT  A2001 (-3.5A) None None None 4TT  A2001 (-4.5A) 4TT  A2001 (-3.7A) 4TT  A2001 (-4.8A) None	0.47A	85.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3vid	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	10 / 12	LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 VAL A 899 VAL A 916 PHE A 918 GLY A 922 LEU A1035	4TT  A2001 ( 4.0A) 4TT  A2001 ( 4.5A) 4TT  A2001 (-3.5A) None None None None 4TT  A2001 (-4.5A) 4TT  A2001 (-3.7A) 4TT  A2001 (-4.8A)	0.58A	85.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3wig	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 (Homo sapiens)	8 / 12	LEU A  75 VAL A  83 ALA A  96 LYS A  98 VAL A 128 GLY A 150 LEU A 198 CYH A 208	ANP  A 401 (-3.8A) ANP  A 401 ( 4.3A) ANP  A 401 (-3.2A) ANP  A 401 (-2.7A) CHU  A 403 (-4.2A) ANP  A 401 ( 4.3A) ANP  A 401 (-4.8A) CHU  A 403 ( 3.7A)	1.21A	24.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	10 / 12	LEU A 840 VAL A 848 ALA A 866 GLU A 885 VAL A 899 VAL A 916 PHE A 918 GLY A 922 LEU A1035 CYH A1045	LEV  A1201 ( 3.8A) LEV  A1201 ( 4.9A) LEV  A1201 (-3.5A) LEV  A1201 (-3.7A) None LEV  A1201 ( 4.6A) LEV  A1201 (-4.7A) LEV  A1201 (-3.6A) LEV  A1201 (-4.8A) GOL  A1210 ( 3.3A)	0.47A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	10 / 12	LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 VAL A 916 PHE A 918 GLY A 922 LEU A1035 CYH A1045	LEV  A1201 ( 3.8A) LEV  A1201 ( 4.9A) LEV  A1201 (-3.5A) None LEV  A1201 (-3.7A) LEV  A1201 ( 4.6A) LEV  A1201 (-4.7A) LEV  A1201 (-3.6A) LEV  A1201 (-4.8A) GOL  A1210 ( 3.3A)	0.61A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3zdu	CYCLIN-DEPENDENT KINASE-LIKE 3 (Homo sapiens)	8 / 12	VAL A  18 ALA A  31 LYS A  33 GLU A  50 VAL A  63 PHE A  81 LEU A 132 CYH A 142	38R  A 350 ( 4.8A) 38R  A 350 (-3.4A) 38R  A 350 (-2.9A) 38R  A 350 ( 4.8A) 38R  A 350 ( 4.9A) 38R  A 350 (-4.2A) 38R  A 350 (-4.3A) 38R  A 350 ( 3.9A)	0.65A	27.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4agd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	12 / 12	LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 VAL A 899 VAL A 916 PHE A 918 GLY A 922 LEU A1035 CYH A1045 PHE A1047	B49  A2000 (-3.7A) None B49  A2000 (-3.5A) B49  A2000 (-3.0A) None B49  A2000 ( 4.6A) B49  A2000 (-4.8A) B49  A2000 (-4.4A) B49  A2000 ( 3.7A) B49  A2000 (-4.5A) B49  A2000 ( 4.1A) B49  A2000 (-4.0A)	0.57A	89.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4agu	CYCLIN-DEPENDENT KINASE-LIKE 1 (Homo sapiens)	7 / 12	VAL A  18 ALA A  31 LYS A  33 GLU A  51 VAL A  64 LEU A 133 CYH A 143	D15  A 500 (-4.6A) D15  A 500 (-3.4A) D15  A 500 ( 4.1A) None None D15  A 500 (-4.5A) D15  A 500 ( 4.0A)	0.51A	27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4bc6	SERINE/THREONINE-PRO TEIN KINASE 10 (Homo sapiens)	7 / 12	LEU A  42 VAL A  50 ALA A  63 LYS A  65 PHE A 112 GLY A 116 LEU A 164	XZN  A1317 (-3.6A) XZN  A1317 ( 4.7A) XZN  A1317 (-3.5A) XZN  A1317 (-4.1A) XZN  A1317 (-4.5A) XZN  A1317 ( 3.7A) XZN  A1317 (-4.7A)	0.80A	27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4bc6	SERINE/THREONINE-PRO TEIN KINASE 10 (Homo sapiens)	7 / 12	LEU A  42 VAL A  50 ALA A  63 VAL A  94 PHE A 112 GLY A 116 LEU A 164	XZN  A1317 (-3.6A) XZN  A1317 ( 4.7A) XZN  A1317 (-3.5A) XZN  A1317 (-4.4A) XZN  A1317 (-4.5A) XZN  A1317 ( 3.7A) XZN  A1317 (-4.7A)	0.74A	27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4crs	SERINE/THREONINE-PRO TEIN KINASE N2 (Homo sapiens)	8 / 12	LEU A 663 VAL A 671 ALA A 684 LYS A 686 GLU A 705 VAL A 721 GLY A 743 LEU A 789	AGS  A1985 (-4.2A) AGS  A1985 (-4.6A) AGS  A1985 (-3.5A) AGS  A1985 (-3.0A) None None None AGS  A1985 (-4.8A)	0.67A	24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4eut	SERINE/THREONINE-PRO TEIN KINASE TBK1 (Homo sapiens)	8 / 12	LEU A  15 VAL A  23 ALA A  36 LYS A  38 GLU A  55 VAL A  68 PHE A  88 GLY A  92	BX7  A 401 (-3.7A) BX7  A 401 (-4.4A) BX7  A 401 (-3.4A) BX7  A 401 ( 4.0A) None None BX7  A 401 ( 4.6A) BX7  A 401 (-3.5A)	0.60A	21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4euu	SERINE/THREONINE-PRO TEIN KINASE TBK1 (Homo sapiens)	8 / 12	LEU A  15 VAL A  23 ALA A  36 LYS A  38 GLU A  55 VAL A  68 PHE A  88 GLY A  92	BX7  A 401 (-3.9A) BX7  A 401 ( 4.6A) BX7  A 401 (-3.4A) BX7  A 401 (-3.5A) None None BX7  A 401 ( 4.6A) BX7  A 401 (-3.3A)	0.53A	25.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4f4p	TYROSINE-PROTEIN KINASE SYK (Homo sapiens)	8 / 12	LEU A 377 VAL A 385 ALA A 400 LYS A 402 GLU A 420 VAL A 433 GLY A 454 LEU A 501	0SB  A 701 ( 3.9A) 0SB  A 701 (-4.0A) 0SB  A 701 (-3.3A) 0SB  A 701 ( 4.8A) None None 0SB  A 701 (-3.5A) 0SB  A 701 (-4.4A)	0.86A	33.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4fg8	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE 1 (Homo sapiens)	7 / 12	LEU A  26 VAL A  34 ALA A  47 LYS A  49 VAL A  79 GLY A 101 LEU A 148	ATP  A 401 (-3.8A) ATP  A 401 (-4.1A) ATP  A 401 (-3.6A) ATP  A 401 (-3.0A) ATP  A 401 (-4.7A) None ATP  A 401 (-4.6A)	0.76A	27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4fie	SERINE/THREONINE-PRO TEIN KINASE PAK 4 (Homo sapiens)	8 / 12	VAL A 335 ALA A 348 LYS A 350 GLU A 366 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ANP  A1001 (-4.7A) ANP  A1001 (-3.6A) ANP  A1001 (-3.0A) ANP  A1001 (-3.6A) None ANP  A1001 ( 4.6A) None ANP  A1001 (-4.7A)	0.74A	23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4fl3	TYROSINE-PROTEIN KINASE SYK (Homo sapiens)	7 / 12	LEU A 377 VAL A 385 ALA A 400 LYS A 402 VAL A 433 GLY A 454 LEU A 501	ANP  A 701 ( 4.6A) ANP  A 701 (-4.1A) ANP  A 701 (-3.3A) ANP  A 701 (-2.7A) ANP  A 701 (-4.8A) ANP  A 701 ( 4.2A) ANP  A 701 (-4.5A)	0.78A	22.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	8 / 12	LEU A1122 VAL A1130 ALA A1148 LYS A1150 GLU A1167 VAL A1180 GLY A1202 LEU A1256	0UV  A1501 (-3.8A) 0UV  A1501 (-4.5A) 0UV  A1501 (-3.4A) 0UV  A1501 (-3.7A) None 0UV  A1501 ( 4.9A) 0UV  A1501 (-3.6A) 0UV  A1501 (-4.6A)	0.88A	35.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	8 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 VAL A 884 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.45A	34.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4idt	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 (Homo sapiens)	8 / 12	LEU A 406 VAL A 414 ALA A 427 LYS A 429 GLU A 440 GLY A 475 LEU A 522 CYH A 533	T28  A 701 (-3.8A) T28  A 701 (-4.7A) T28  A 701 (-3.0A) T28  A 701 ( 3.8A) None T28  A 701 ( 3.0A) T28  A 701 (-3.9A) T28  A 701 (-3.7A)	0.75A	25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4idt	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 (Homo sapiens)	8 / 12	LEU A 406 VAL A 414 ALA A 427 LYS A 429 VAL A 453 GLY A 475 LEU A 522 CYH A 533	T28  A 701 (-3.8A) T28  A 701 (-4.7A) T28  A 701 (-3.0A) T28  A 701 ( 3.8A) None T28  A 701 ( 3.0A) T28  A 701 (-3.9A) T28  A 701 (-3.7A)	0.71A	25.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4k33	FIBROBLAST GROWTH FACTOR RECEPTOR 3 (Homo sapiens)	8 / 12	LEU A 478 VAL A 486 ALA A 506 LYS A 508 GLU A 525 VAL A 555 GLY A 561 LEU A 624	ACP  A 801 (-3.8A) ACP  A 801 (-4.2A) ACP  A 801 (-3.3A) ACP  A 801 (-2.7A) ACP  A 801 ( 4.8A) ACP  A 801 (-4.7A) ACP  A 801 ( 4.6A) ACP  A 801 (-4.4A)	0.63A	52.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4ks8	SERINE/THREONINE-PRO TEIN KINASE PAK 6 (Homo sapiens)	7 / 12	VAL A 421 ALA A 434 LYS A 436 GLU A 452 PHE A 483 GLY A 487 LEU A 533	None B49  A 701 (-3.2A) None None B49  A 701 (-4.3A) B49  A 701 ( 3.7A) B49  A 701 (-4.5A)	0.73A	27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4ks8	SERINE/THREONINE-PRO TEIN KINASE PAK 6 (Homo sapiens)	7 / 12	VAL A 421 ALA A 434 LYS A 436 VAL A 465 PHE A 483 GLY A 487 LEU A 533	None B49  A 701 (-3.2A) None None B49  A 701 (-4.3A) B49  A 701 ( 3.7A) B49  A 701 (-4.5A)	0.65A	27.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4l52	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7, TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1 CHIMERA (Homo sapiens)	8 / 12	VAL A  50 ALA A  61 LYS A  63 GLU A  77 VAL A  90 GLY A 110 LEU A 163 CYH A 174	1UL  A 501 ( 4.9A) 1UL  A 501 (-3.1A) None None None 1UL  A 501 ( 3.7A) 1UL  A 501 (-4.3A) 1UL  A 501 (-3.6A)	0.73A	30.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	9 / 12	LEU A  46 VAL A  54 ALA A  67 LYS A  69 GLU A  85 VAL A  99 GLY A 128 LEU A 180 CYH A 190	SIN  A 401 ( 3.9A) None SIN  A 401 ( 3.7A) None None None SIN  A 401 (-3.5A) SIN  A 401 ( 4.5A) None	0.66A	25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4oli	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	7 / 12	LEU A 903 VAL A 911 ALA A 928 LYS A 930 GLU A 947 GLY A 984 LEU A1030	2TT  A1202 (-3.5A) 2TT  A1202 (-4.5A) 2TT  A1202 ( 3.9A) None None 2TT  A1202 (-3.4A) 2TT  A1202 (-4.4A)	0.72A	21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4rt7	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	10 / 12	LEU A 616 VAL A 624 ALA A 642 LYS A 644 GLU A 661 VAL A 675 GLY A 697 LEU A 818 CYH A 828 PHE A 830	P30  A1001 (-3.8A) None P30  A1001 (-3.4A) P30  A1001 (-3.4A) P30  A1001 (-3.6A) None P30  A1001 (-3.4A) P30  A1001 (-4.6A) P30  A1001 (-4.1A) P30  A1001 (-3.9A)	0.39A	40.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4wb7	DNAJ HOMOLOG SUBFAMILY B MEMBER 1,CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	8 / 12	LEU A 104 VAL A 112 ALA A 125 LYS A 127 GLU A 146 VAL A 159 GLY A 181 LEU A 228	ATP  A 501 ( 4.3A) ATP  A 501 (-4.0A) ATP  A 501 (-3.4A) ATP  A 501 (-2.6A) None None None ATP  A 501 (-4.5A)	0.63A	23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4wsq	AP2-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	8 / 12	LEU A  52 VAL A  60 ALA A  72 GLU A  90 VAL A 104 PHE A 128 LEU A 183 CYH A 193	KSA  A 405 ( 4.0A) KSA  A 405 ( 4.9A) KSA  A 405 (-3.2A) None None KSA  A 405 (-4.8A) KSA  A 405 (-4.6A) KSA  A 405 (-3.4A)	0.65A	23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4wsq	AP2-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	8 / 12	LEU A  52 VAL A  60 ALA A  72 VAL A 104 PHE A 128 GLY A 132 LEU A 183 CYH A 193	KSA  A 405 ( 4.0A) KSA  A 405 ( 4.9A) KSA  A 405 (-3.2A) None KSA  A 405 (-4.8A) KSA  A 405 (-3.5A) KSA  A 405 (-4.6A) KSA  A 405 (-3.4A)	0.40A	23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	VAL A 335 ALA A 348 LYS A 350 GLU A 366 PHE A 397 GLY A 401 LEU A 447	ATP  A 601 (-4.4A) ATP  A 601 ( 3.7A) ATP  A 601 (-2.8A) ATP  A 601 ( 3.7A) ATP  A 601 (-4.6A) None None	0.73A	25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	VAL A 335 ALA A 348 LYS A 350 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ATP  A 601 (-4.4A) ATP  A 601 ( 3.7A) ATP  A 601 (-2.8A) None ATP  A 601 (-4.6A) None None	0.68A	25.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xcu	FIBROBLAST GROWTH FACTOR RECEPTOR 4 (Homo sapiens)	8 / 12	LEU A 473 VAL A 481 ALA A 501 LYS A 503 GLU A 520 VAL A 550 GLY A 556 LEU A 619	40M  A1002 ( 4.6A) 40M  A1002 ( 4.5A) 40M  A1002 ( 4.1A) 40M  A1002 (-4.0A) 40M  A1002 (-3.7A) 40M  A1002 (-4.7A) 40M  A1002 ( 3.7A) 40M  A1002 (-4.5A)	0.74A	51.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	LEU B 267 VAL B 275 ALA B 288 LYS B 290 VAL B 318 PHE B 336 GLY B 340 LEU B 389	1N1  B 601 (-3.7A) 1N1  B 601 ( 4.9A) 1N1  B 601 (-3.5A) 1N1  B 601 (-4.6A) 1N1  B 601 ( 4.3A) 1N1  B 601 ( 4.2A) 1N1  B 601 (-3.5A) 1N1  B 601 (-4.3A)	0.74A	29.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xuf	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	10 / 12	LEU A 616 VAL A 624 ALA A 642 LYS A 644 GLU A 661 VAL A 675 GLY A 697 LEU A 818 CYH A 828 PHE A 830	P30  A1001 (-4.0A) P30  A1001 ( 4.8A) P30  A1001 (-3.5A) P30  A1001 ( 4.0A) P30  A1001 (-3.1A) None P30  A1001 (-3.5A) P30  A1001 (-4.3A) P30  A1001 (-4.8A) P30  A1001 ( 4.1A)	0.68A	51.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4yhj	G PROTEIN-COUPLED RECEPTOR KINASE 4 (Homo sapiens)	8 / 12	LEU A 193 VAL A 201 ALA A 214 LYS A 216 GLU A 235 VAL A 248 GLY A 270 LEU A 319	AN2  A 601 ( 4.2A) AN2  A 601 (-4.0A) AN2  A 601 (-3.6A) AN2  A 601 ( 3.9A) None None None None	0.98A	21.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5a46	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens)	8 / 12	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLU A 531 VAL A 561 GLY A 567 LEU A 630	38O  A1769 (-3.2A) 38O  A1769 (-4.5A) 38O  A1769 (-3.6A) 38O  A1769 ( 3.1A) EDO  A1766 (-4.1A) 38O  A1769 (-4.3A) 38O  A1769 (-3.4A) 38O  A1769 (-4.6A)	0.58A	46.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5e8y	TGF-BETA RECEPTOR TYPE-2 (Homo sapiens)	8 / 12	VAL A 258 ALA A 275 LYS A 277 GLU A 290 PHE A 327 GLY A 331 LEU A 386 CYH A 396	STU  A 601 (-4.0A) STU  A 601 (-3.1A) STU  A 601 (-2.4A) STU  A 601 ( 3.8A) STU  A 601 (-3.4A) STU  A 601 (-3.5A) STU  A 601 (-3.9A) STU  A 601 (-3.2A)	0.75A	29.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5f1z	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	7 / 12	LEU A 903 VAL A 911 ALA A 928 LYS A 930 GLU A 947 GLY A 984 LEU A1030	5U3  A1200 (-3.8A) 5U3  A1200 ( 4.4A) 5U3  A1200 (-3.5A) None None 5U3  A1200 (-3.2A) 5U3  A1200 (-4.4A)	0.51A	31.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5fm2	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET (Homo sapiens)	7 / 12	LEU A 730 VAL A 738 ALA A 756 LYS A 758 VAL A 804 GLY A 810 LEU A 881	PP1  A2012 (-4.6A) PP1  A2012 (-4.4A) PP1  A2012 (-3.2A) PP1  A2012 (-4.1A) PP1  A2012 (-4.5A) PTR  A 809 (-2.4A) PP1  A2012 (-4.6A)	0.66A	41.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	10 / 12	LEU A 599 VAL A 607 ALA A 625 LYS A 627 GLU A 644 VAL A 658 GLY A 680 LEU A 825 CYH A 835 PHE A 837	748  A1001 (-3.8A) 748  A1001 ( 4.7A) 748  A1001 (-3.7A) 748  A1001 (-4.0A) 748  A1001 (-3.3A) 748  A1001 ( 4.8A) 748  A1001 ( 4.0A) 748  A1001 (-4.3A) 748  A1001 (-4.5A) 748  A1001 (-3.7A)	0.43A	48.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5i3o	BMP-2-INDUCIBLE PROTEIN KINASE (Homo sapiens)	8 / 12	LEU A  57 VAL A  65 ALA A  77 LYS A  79 VAL A 109 GLY A 136 LEU A 187 CYH A 197	IDV  A 401 (-3.8A) IDV  A 401 (-4.6A) IDV  A 401 (-3.6A) IDV  A 401 ( 4.8A) None IDV  A 401 (-3.4A) IDV  A 401 (-4.4A) IDV  A 401 (-3.6A)	0.67A	25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5i3o	BMP-2-INDUCIBLE PROTEIN KINASE (Homo sapiens)	8 / 12	VAL A  65 ALA A  77 LYS A  79 GLU A  95 VAL A 109 GLY A 136 LEU A 187 CYH A 197	IDV  A 401 (-4.6A) IDV  A 401 (-3.6A) IDV  A 401 ( 4.8A) None None IDV  A 401 (-3.4A) IDV  A 401 (-4.4A) IDV  A 401 (-3.6A)	0.79A	25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	8 / 12	VAL A  30 ALA A  43 LYS A  45 GLU A  61 VAL A  74 PHE A  92 GLY A  96 LEU A 143	6G2  A 901 ( 4.9A) 6G2  A 901 (-3.2A) 6G2  A 901 ( 3.9A) None None 6G2  A 901 (-4.1A) 6G2  A 901 (-3.6A) 6G2  A 901 (-4.7A)	0.55A	21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5jzn	SERINE/THREONINE-PRO TEIN KINASE DCLK1 (Homo sapiens)	7 / 12	VAL A 404 ALA A 417 LYS A 419 GLU A 436 VAL A 449 GLY A 471 LEU A 518	GUI  A 701 (-4.4A) GUI  A 701 ( 3.9A) GUI  A 701 (-3.1A) None None GUI  A 701 (-3.6A) GUI  A 701 (-4.4A)	0.79A	27.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5uuu	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	7 / 12	VAL A 205 ALA A 218 LYS A 220 GLU A 239 VAL A 255 GLY A 277 LEU A 324	QRW  A 601 (-4.7A) QRW  A 601 (-3.4A) QRW  A 601 (-3.0A) QRW  A 601 (-3.9A) None None None	0.72A	22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5vef	SERINE/THREONINE-PRO TEIN KINASE PAK 4 (Homo sapiens)	8 / 12	VAL A 335 ALA A 348 LYS A 350 GLU A 366 VAL A 379 PHE A 397 GLY A 401 LEU A 447	M77  A 601 (-4.5A) M77  A 601 ( 3.5A) M77  A 601 ( 4.7A) None None M77  A 601 (-4.1A) M77  A 601 ( 4.8A) M77  A 601 (-4.6A)	0.70A	26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5vil	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (Homo sapiens)	8 / 12	LEU A 686 VAL A 694 ALA A 707 LYS A 709 GLU A 725 VAL A 738 GLY A 760 LEU A 810	9E1  A1001 (-3.7A) 9E1  A1001 ( 4.0A) 9E1  A1001 (-3.5A) 9E1  A1001 (-2.8A) None 9E1  A1001 (-4.1A) 9E1  A1001 (-3.4A) 9E1  A1001 (-4.5A)	0.40A	12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6c0t	CGMP-DEPENDENT PROTEIN KINASE 1 (Homo sapiens)	7 / 12	LEU A 366 VAL A 374 ALA A 388 LYS A 390 GLU A 409 VAL A 422 GLY A 444	EE4  A 701 ( 4.6A) EE4  A 701 (-4.4A) EE4  A 701 (-3.3A) DMS  A 702 (-3.5A) DMS  A 702 ( 4.2A) None None	0.74A	12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6c7y	TYROSINE-PROTEIN KINASE JAK1 (Homo sapiens)	9 / 12	LEU A 881 VAL A 889 ALA A 906 LYS A 908 GLU A 925 VAL A 938 PHE A 958 GLY A 962 LEU A1010	ADP  A1201 ( 4.5A) ADP  A1201 (-4.3A) ADP  A1201 (-3.4A) ADP  A1201 (-2.8A) None None None ADP  A1201 ( 4.1A) ADP  A1201 (-4.5A)	0.59A	14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6fyl	DUAL SPECIFICITY PROTEIN KINASE CLK2 (Homo sapiens)	8 / 12	LEU A 169 VAL A 177 ALA A 191 LYS A 193 GLU A 208 VAL A 227 GLY A 247 LEU A 297	3NG  A 501 (-3.9A) 3NG  A 501 ( 4.4A) 3NG  A 501 (-3.3A) 3NG  A 501 (-3.0A) 3NG  A 501 ( 4.9A) None None None	1.07A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6fyv	DUAL SPECIFICITY PROTEIN KINASE CLK4 (Homo sapiens)	8 / 12	LEU A 167 VAL A 175 ALA A 189 LYS A 191 GLU A 206 VAL A 225 GLY A 245 LEU A 295	3NG  A 501 (-3.9A) 3NG  A 501 ( 4.3A) 3NG  A 501 (-3.5A) 3NG  A 501 (-2.7A) 3NG  A 501 ( 4.7A) None None None	1.15A	undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1rjb	FL CYTOKINE RECEPTOR (Homo sapiens)	8 / 12	LEU A 616 VAL A 624 ALA A 642 LYS A 644 GLU A 661 GLY A 697 LEU A 818 CYH A 828	None	0.53A	47.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1t46	HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG (Homo sapiens)	10 / 12	LEU A 595 VAL A 603 ALA A 621 LYS A 623 GLU A 640 LEU A 644 GLY A 676 LEU A 799 CYH A 809 PHE A 811	STI  A   3 ( 3.8A) STI  A   3 ( 4.6A) STI  A   3 (-3.5A) STI  A   3 (-3.7A) STI  A   3 (-3.6A) STI  A   3 (-4.4A) STI  A   3 ( 3.8A) STI  A   3 (-4.4A) STI  A   3 (-4.5A) STI  A   3 (-3.6A)	0.48A	49.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1u59	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	6 / 12	LEU A 344 VAL A 352 ALA A 367 GLU A 386 GLY A 420 LEU A 468	STU  A 100 (-3.8A) STU  A 100 (-4.8A) STU  A 100 (-3.2A) None STU  A 100 (-3.5A) STU  A 100 (-4.5A)	0.49A	30.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1zlt	SERINE/THREONINE-PRO TEIN KINASE CHK1 (Homo sapiens)	7 / 12	LEU A  15 VAL A  23 ALA A  36 LYS A  38 GLU A  55 GLY A  90 LEU A 137	HYM  A 400 (-4.2A) HYM  A 400 (-4.3A) HYM  A 400 (-3.5A) HYM  A 400 (-3.2A) None None HYM  A 400 (-4.5A)	0.50A	23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2a2a	DEATH-ASSOCIATED PROTEIN KINASE 2 (Homo sapiens)	6 / 12	LEU A  19 VAL A  27 ALA A  40 LYS A  42 GLU A  64 LEU A  68	None None GOL  A3001 (-3.5A) None None None	0.53A	25.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 12	LEU X  17 VAL X  25 ALA X  37 LYS X  39 GLU X  54 GLY X  88 LEU X 137	STU  X 902 (-3.8A) STU  X 902 ( 4.8A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) STU  X 902 ( 4.4A) STU  X 902 (-3.5A) STU  X 902 (-4.4A)	0.60A	32.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2eu9	DUAL SPECIFICITY PROTEIN KINASE CLK3 (Homo sapiens)	6 / 12	LEU A 162 VAL A 170 ALA A 184 LYS A 186 GLU A 201 LEU A 205	None	0.58A	22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2hw6	MAP KINASE-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 1 (Homo sapiens)	6 / 12	LEU A  55 VAL A  63 ALA A  76 GLY A 130 LEU A 177 CYH A 190	None	0.37A	24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2hw6	MAP KINASE-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 1 (Homo sapiens)	7 / 12	LEU A  55 VAL A  63 LYS A  78 LEU A  98 GLY A 130 LEU A 177 CYH A 190	None	0.62A	24.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	LEU A 248 VAL A 256 ALA A 269 LYS A 271 GLU A 286 GLY A 321 LEU A 370 PHE A 382	GIN  A 600 ( 4.6A) GIN  A 600 ( 4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-3.6A) GIN  A 600 (-3.6A) None GIN  A 600 (-4.7A) GIN  A 600 (-4.0A)	0.42A	35.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2iwi	SERINE/THREONINE-PRO TEIN KINASE PIM-2 (Homo sapiens)	6 / 12	LEU A  38 VAL A  46 ALA A  59 GLU A  83 LEU A  87 LEU A 170	HB1  A1289 ( 4.1A) HB1  A1289 (-3.6A) HB1  A1289 ( 3.7A) None None HB1  A1289 (-4.7A)	0.58A	24.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2ogv	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR PRECURSOR (Homo sapiens)	6 / 12	LEU A 588 VAL A 596 ALA A 614 GLU A 633 GLY A 669 LEU A 785	None	0.50A	48.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2ogv	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR PRECURSOR (Homo sapiens)	6 / 12	LEU A 588 VAL A 596 ALA A 614 LYS A 616 GLU A 633 GLY A 669	None	0.53A	48.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2psq	FIBROBLAST GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	LEU A 487 VAL A 495 ALA A 515 GLU A 534 VAL A 564 GLY A 570 LEU A 633	None	0.55A	50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2r4b	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	6 / 12	LEU A 724 VAL A 732 ALA A 749 LYS A 751 GLY A 802 LEU A 850	GW7  A   1 ( 4.2A) GW7  A   1 ( 4.8A) GW7  A   1 (-3.3A) GW7  A   1 (-3.9A) GW7  A   1 (-3.6A) GW7  A   1 (-4.2A)	0.58A	35.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2w4k	DEATH-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	6 / 12	LEU A  19 VAL A  27 ALA A  40 LYS A  42 GLU A  64 LEU A  68	ADP  A1303 ( 3.9A) ADP  A1303 (-4.0A) ADP  A1303 (-3.5A) ADP  A1303 (-2.7A) ADP  A1303 ( 4.8A) None	0.58A	25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2xik	SERINE/THREONINE PROTEIN KINASE 25 (Homo sapiens)	6 / 12	VAL A  34 ALA A  47 GLU A  66 LEU A  70 GLY A 101 LEU A 147	J60  A1294 ( 4.9A) J60  A1294 (-3.3A) None None J60  A1294 ( 3.8A) J60  A1294 (-4.8A)	0.55A	27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	6 / 12	LEU A  68 VAL A  76 ALA A  92 LYS A  94 GLY A 147 LEU A 194	STU  A   1 (-3.8A) None STU  A   1 (-3.3A) STU  A   1 (-2.8A) STU  A   1 ( 3.9A) STU  A   1 (-4.6A)	0.44A	27.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3b2t	FIBROBLAST GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	LEU A 487 VAL A 495 ALA A 515 LYS A 517 VAL A 564 GLY A 570 LEU A 633	M33  A1996 (-4.0A) M33  A1996 ( 4.7A) M33  A1996 (-3.3A) M33  A1996 ( 4.5A) None M33  A1996 ( 4.8A) M33  A1996 (-4.5A)	0.46A	49.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3c4f	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	7 / 12	LEU A 484 VAL A 492 ALA A 512 GLU A 531 VAL A 561 GLY A 567 LEU A 630	C4F  A   1 ( 3.9A) None C4F  A   1 (-3.3A) None C4F  A   1 ( 4.8A) None C4F  A   1 (-4.6A)	0.59A	54.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	6 / 12	VAL A 209 ALA A 220 LYS A 222 GLU A 236 GLY A 272 LEU A 321	None	0.54A	32.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3f2a	PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE PIM-1 (Homo sapiens)	7 / 12	LEU A  44 VAL A  52 ALA A  65 LYS A  67 GLU A  89 LEU A  93 LEU A 174	985  A   1 (-4.1A) 985  A   1 (-4.5A) 985  A   1 (-3.5A) 985  A   1 ( 2.8A) MG  A 314 (-3.6A) MG  A 314 ( 4.8A) 985  A   1 (-4.8A)	0.54A	28.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3hng	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	11 / 12	LEU A 833 VAL A 841 ALA A 859 LYS A 861 GLU A 878 LEU A 882 VAL A 909 GLY A 915 LEU A1029 CYH A1039 PHE A1041	8ST  A2001 ( 4.7A) 8ST  A2001 ( 4.6A) 8ST  A2001 ( 3.8A) 8ST  A2001 (-4.0A) 8ST  A2001 (-3.7A) None 8ST  A2001 (-4.1A) None None 8ST  A2001 (-4.2A) 8ST  A2001 ( 3.7A)	0.51A	67.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3mvj	CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	7 / 12	LEU A  49 VAL A  57 ALA A  70 GLU A  91 LEU A  95 GLY A 126 LEU A 173	XFE  A 351 (-4.2A) XFE  A 351 ( 4.5A) XFE  A 351 (-3.2A) None None None XFE  A 351 (-4.6A)	0.52A	25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3mvj	CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	6 / 12	LEU A  49 VAL A  57 ALA A  70 LYS A  72 GLU A  91 LEU A  95	XFE  A 351 (-4.2A) XFE  A 351 ( 4.5A) XFE  A 351 (-3.2A) None None None	0.52A	25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3nuu	PKB-LIKE (Homo sapiens)	7 / 12	LEU A  88 VAL A  96 ALA A 109 LYS A 111 GLU A 130 GLY A 165 LEU A 212	JOZ  A 361 (-4.1A) JOZ  A 361 ( 4.7A) JOZ  A 361 (-3.4A) SO4  A   5 (-2.8A) SO4  A   5 (-3.1A) None None	0.51A	25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	8 / 12	LEU A 192 VAL A 200 ALA A 213 LYS A 215 GLU A 234 LEU A 238 GLY A 269 LEU A 318	AMP  A 577 ( 4.3A) AMP  A 577 (-4.3A) AMP  A 577 (-3.4A) AMP  A 577 (-2.8A) None None None AMP  A 577 (-4.8A)	0.76A	22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	6 / 12	LEU A 726 VAL A 734 ALA A 751 LYS A 753 GLY A 804 LEU A 852	03Q  A   1 (-3.8A) 03Q  A   1 (-4.5A) 03Q  A   1 (-3.1A) 03Q  A   1 (-4.7A) 03Q  A   1 ( 3.9A) 03Q  A   1 (-4.4A)	0.50A	28.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3tt0	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	8 / 12	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLU A 531 VAL A 561 GLY A 567 LEU A 630	07J  A   1 ( 4.3A) 07J  A   1 (-4.0A) 07J  A   1 (-3.5A) 07J  A   1 (-4.5A) 07J  A   1 (-3.8A) 07J  A   1 (-4.7A) 07J  A   1 (-3.7A) 07J  A   1 ( 4.4A)	0.60A	50.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	7 / 12	LEU A 361 VAL A 369 ALA A 382 GLU A 403 LEU A 407 GLY A 439 LEU A 486	07U  A   1 ( 4.8A) 07U  A   1 (-4.8A) 07U  A   1 (-3.3A) 07U  A   1 ( 4.8A) None None 07U  A   1 (-4.3A)	0.68A	23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	7 / 12	LEU A 361 VAL A 369 ALA A 382 LYS A 384 GLU A 403 LEU A 407 LEU A 486	07U  A   1 ( 4.8A) 07U  A   1 (-4.8A) 07U  A   1 (-3.3A) 07U  A   1 (-3.0A) 07U  A   1 ( 4.8A) None 07U  A   1 (-4.3A)	0.65A	23.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3vid	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	9 / 12	LEU A 840 VAL A 848 ALA A 866 GLU A 885 LEU A 889 VAL A 916 GLY A 922 LEU A1035 CYH A1045	4TT  A2001 ( 4.0A) 4TT  A2001 ( 4.5A) 4TT  A2001 (-3.5A) None None None 4TT  A2001 (-3.7A) 4TT  A2001 (-4.8A) None	0.44A	85.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3vid	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 LEU A 889 VAL A 916	4TT  A2001 ( 4.0A) 4TT  A2001 ( 4.5A) 4TT  A2001 (-3.5A) None None None None	0.56A	85.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	9 / 12	LEU A 840 VAL A 848 ALA A 866 GLU A 885 LEU A 889 VAL A 916 GLY A 922 LEU A1035 CYH A1045	LEV  A1201 ( 3.8A) LEV  A1201 ( 4.9A) LEV  A1201 (-3.5A) LEV  A1201 (-3.7A) LEV  A1201 ( 4.4A) LEV  A1201 ( 4.6A) LEV  A1201 (-3.6A) LEV  A1201 (-4.8A) GOL  A1210 ( 3.3A)	0.46A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4agd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	10 / 12	ILE A 804 LEU A 840 VAL A 848 ALA A 866 GLU A 885 VAL A 916 GLY A 922 LEU A1035 CYH A1045 PHE A1047	None B49  A2000 (-3.7A) None B49  A2000 (-3.5A) None B49  A2000 (-4.8A) B49  A2000 ( 3.7A) B49  A2000 (-4.5A) B49  A2000 ( 4.1A) B49  A2000 (-4.0A)	0.42A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4agd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	10 / 12	ILE A 804 LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 GLY A 922 LEU A1035 CYH A1045 PHE A1047	None B49  A2000 (-3.7A) None B49  A2000 (-3.5A) B49  A2000 (-3.0A) None B49  A2000 ( 3.7A) B49  A2000 (-4.5A) B49  A2000 ( 4.1A) B49  A2000 (-4.0A)	0.52A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4agd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	10 / 12	LEU A 840 VAL A 848 ALA A 866 GLU A 885 LEU A 889 VAL A 916 GLY A 922 LEU A1035 CYH A1045 PHE A1047	B49  A2000 (-3.7A) None B49  A2000 (-3.5A) None None B49  A2000 (-4.8A) B49  A2000 ( 3.7A) B49  A2000 (-4.5A) B49  A2000 ( 4.1A) B49  A2000 (-4.0A)	0.45A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4agd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	10 / 12	LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLU A 885 LEU A 889 GLY A 922 LEU A1035 CYH A1045 PHE A1047	B49  A2000 (-3.7A) None B49  A2000 (-3.5A) B49  A2000 (-3.0A) None None B49  A2000 ( 3.7A) B49  A2000 (-4.5A) B49  A2000 ( 4.1A) B49  A2000 (-4.0A)	0.56A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4agu	CYCLIN-DEPENDENT KINASE-LIKE 1 (Homo sapiens)	7 / 12	VAL A  18 ALA A  31 LYS A  33 GLU A  51 LEU A  55 LEU A 133 CYH A 143	D15  A 500 (-4.6A) D15  A 500 (-3.4A) D15  A 500 ( 4.1A) None None D15  A 500 (-4.5A) D15  A 500 ( 4.0A)	0.60A	25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4crs	SERINE/THREONINE-PRO TEIN KINASE N2 (Homo sapiens)	6 / 12	LEU A 663 VAL A 671 ALA A 684 LYS A 686 GLY A 743 LEU A 789	AGS  A1985 (-4.2A) AGS  A1985 (-4.6A) AGS  A1985 (-3.5A) AGS  A1985 (-3.0A) None AGS  A1985 (-4.8A)	0.52A	23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4eut	SERINE/THREONINE-PRO TEIN KINASE TBK1 (Homo sapiens)	7 / 12	LEU A  15 VAL A  23 ALA A  36 LYS A  38 GLU A  55 LEU A  59 GLY A  92	BX7  A 401 (-3.7A) BX7  A 401 (-4.4A) BX7  A 401 (-3.4A) BX7  A 401 ( 4.0A) None None BX7  A 401 (-3.5A)	0.51A	22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4euu	SERINE/THREONINE-PRO TEIN KINASE TBK1 (Homo sapiens)	7 / 12	LEU A  15 VAL A  23 ALA A  36 LYS A  38 GLU A  55 LEU A  59 GLY A  92	BX7  A 401 (-3.9A) BX7  A 401 ( 4.6A) BX7  A 401 (-3.4A) BX7  A 401 (-3.5A) None None BX7  A 401 (-3.3A)	0.43A	24.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4f4p	TYROSINE-PROTEIN KINASE SYK (Homo sapiens)	7 / 12	LEU A 377 VAL A 385 ALA A 400 LYS A 402 GLU A 420 GLY A 454 LEU A 501	0SB  A 701 ( 3.9A) 0SB  A 701 (-4.0A) 0SB  A 701 (-3.3A) 0SB  A 701 ( 4.8A) None 0SB  A 701 (-3.5A) 0SB  A 701 (-4.4A)	0.89A	34.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4f99	CELL DIVISION CYCLE 7-RELATED PROTEIN KINASE (Homo sapiens)	6 / 12	VAL A  72 ALA A  88 LYS A  90 GLU A 104 LEU A 108 LEU A 184	ADP  A 601 (-4.0A) ADP  A 601 (-3.5A) ADP  A 601 (-2.6A) None None ADP  A 601 ( 4.9A)	0.55A	22.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	7 / 12	LEU A1122 VAL A1130 ALA A1148 LYS A1150 GLU A1167 GLY A1202 LEU A1256	0UV  A1501 (-3.8A) 0UV  A1501 (-4.5A) 0UV  A1501 (-3.4A) 0UV  A1501 (-3.7A) None 0UV  A1501 (-3.6A) 0UV  A1501 (-4.6A)	0.88A	33.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4gv1	RAC-ALPHA SERINE/THREONINE-PRO TEIN KINASE (Homo sapiens)	7 / 12	LEU A 156 VAL A 164 ALA A 177 LYS A 179 GLU A 198 LEU A 202 GLY A 233	0XZ  A 501 ( 4.1A) 0XZ  A 501 (-4.5A) 0XZ  A 501 (-3.3A) GOL  A 503 ( 2.8A) GOL  A 503 (-3.6A) None None	0.67A	23.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLU A 871 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.44A	31.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hzs	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	6 / 12	LEU A 132 VAL A 140 ALA A 156 LYS A 158 GLY A 211 LEU A 259	None	0.43A	30.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4id7	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	6 / 12	LEU A 132 VAL A 140 ALA A 156 LYS A 158 GLY A 211 LEU A 259	1G0  A 401 ( 4.5A) 1G0  A 401 (-4.4A) 1G0  A 401 (-3.6A) 1G0  A 401 (-3.7A) 1G0  A 401 ( 4.5A) 1G0  A 401 (-4.6A)	0.47A	33.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4idt	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 (Homo sapiens)	7 / 12	LEU A 406 VAL A 414 LYS A 429 GLU A 440 GLY A 475 LEU A 522 CYH A 533	T28  A 701 (-3.8A) T28  A 701 (-4.7A) T28  A 701 ( 3.8A) None T28  A 701 ( 3.0A) T28  A 701 (-3.9A) T28  A 701 (-3.7A)	0.74A	26.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4jxf	SERINE/THREONINE-PRO TEIN KINASE PLK4 (Homo sapiens)	6 / 12	LEU A  18 VAL A  26 ALA A  39 LYS A  41 GLY A  95 LEU A 143	631  A 301 (-3.4A) 631  A 301 (-4.6A) 631  A 301 (-3.3A) 631  A 301 (-2.7A) 631  A 301 ( 3.7A) 631  A 301 (-4.0A)	0.53A	23.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4k33	FIBROBLAST GROWTH FACTOR RECEPTOR 3 (Homo sapiens)	8 / 12	LEU A 478 VAL A 486 ALA A 506 LYS A 508 GLU A 525 VAL A 555 GLY A 561 LEU A 624	ACP  A 801 (-3.8A) ACP  A 801 (-4.2A) ACP  A 801 (-3.3A) ACP  A 801 (-2.7A) ACP  A 801 ( 4.8A) ACP  A 801 (-4.7A) ACP  A 801 ( 4.6A) ACP  A 801 (-4.4A)	0.63A	51.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4l52	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7, TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1 CHIMERA (Homo sapiens)	7 / 12	VAL A  50 ALA A  61 GLU A  77 LEU A  81 GLY A 110 LEU A 163 CYH A 174	1UL  A 501 ( 4.9A) 1UL  A 501 (-3.1A) None None 1UL  A 501 ( 3.7A) 1UL  A 501 (-4.3A) 1UL  A 501 (-3.6A)	0.62A	28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4o27	SERINE/THREONINE-PRO TEIN KINASE 24 (Homo sapiens)	7 / 12	VAL B  38 ALA B  51 LYS B  53 GLU B  70 LEU B  74 GLY B 105 LEU B 151	ADP  B 500 (-4.5A) ADP  B 500 (-3.3A) ADP  B 500 (-3.1A) None None None ADP  B 500 (-4.7A)	0.75A	25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	8 / 12	LEU A  46 VAL A  54 ALA A  67 LYS A  69 GLU A  85 GLY A 128 LEU A 180 CYH A 190	SIN  A 401 ( 3.9A) None SIN  A 401 ( 3.7A) None None SIN  A 401 (-3.5A) SIN  A 401 ( 4.5A) None	0.68A	24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4oli	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	6 / 12	LEU A 903 VAL A 911 ALA A 928 GLU A 947 GLY A 984 LEU A1030	2TT  A1202 (-3.5A) 2TT  A1202 (-4.5A) 2TT  A1202 ( 3.9A) None 2TT  A1202 (-3.4A) 2TT  A1202 (-4.4A)	0.45A	24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4otd	SERINE/THREONINE-PRO TEIN KINASE N1 (Homo sapiens)	6 / 12	LEU A 627 VAL A 635 ALA A 648 LEU A 673 GLY A 707 LEU A 753	None	0.53A	26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4q9z	HUMAN PROTEIN KINASE C THETA (Homo sapiens)	6 / 12	LEU A 386 VAL A 394 ALA A 407 LYS A 409 LEU A 432 LEU A 511	PZW  A 801 (-3.9A) PZW  A 801 (-4.6A) PZW  A 801 (-3.5A) None None PZW  A 801 (-4.8A)	0.57A	24.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4rt7	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	9 / 12	LEU A 616 VAL A 624 ALA A 642 LYS A 644 GLU A 661 GLY A 697 LEU A 818 CYH A 828 PHE A 830	P30  A1001 (-3.8A) None P30  A1001 (-3.4A) P30  A1001 (-3.4A) P30  A1001 (-3.6A) P30  A1001 (-3.4A) P30  A1001 (-4.6A) P30  A1001 (-4.1A) P30  A1001 (-3.9A)	0.30A	43.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4wb7	DNAJ HOMOLOG SUBFAMILY B MEMBER 1,CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	7 / 12	LEU A 104 VAL A 112 ALA A 125 LYS A 127 GLU A 146 GLY A 181 LEU A 228	ATP  A 501 ( 4.3A) ATP  A 501 (-4.0A) ATP  A 501 (-3.4A) ATP  A 501 (-2.6A) None None ATP  A 501 (-4.5A)	0.56A	23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4wb7	DNAJ HOMOLOG SUBFAMILY B MEMBER 1,CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	7 / 12	LEU A 104 VAL A 112 ALA A 125 LYS A 127 LEU A 150 GLY A 181 LEU A 228	ATP  A 501 ( 4.3A) ATP  A 501 (-4.0A) ATP  A 501 (-3.4A) ATP  A 501 (-2.6A) None None ATP  A 501 (-4.5A)	0.60A	23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4wsq	AP2-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	6 / 12	LEU A  52 VAL A  60 ALA A  72 GLY A 132 LEU A 183 CYH A 193	KSA  A 405 ( 4.0A) KSA  A 405 ( 4.9A) KSA  A 405 (-3.2A) KSA  A 405 (-3.5A) KSA  A 405 (-4.6A) KSA  A 405 (-3.4A)	0.36A	24.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xcu	FIBROBLAST GROWTH FACTOR RECEPTOR 4 (Homo sapiens)	6 / 12	LEU A 473 VAL A 481 ALA A 501 LYS A 503 GLU A 520 VAL A 550	40M  A1002 ( 4.6A) 40M  A1002 ( 4.5A) 40M  A1002 ( 4.1A) 40M  A1002 (-4.0A) 40M  A1002 (-3.7A) 40M  A1002 (-4.7A)	0.59A	47.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xuf	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	8 / 12	LEU A 616 VAL A 624 ALA A 642 GLU A 661 GLY A 697 LEU A 818 CYH A 828 PHE A 830	P30  A1001 (-4.0A) P30  A1001 ( 4.8A) P30  A1001 (-3.5A) P30  A1001 (-3.1A) P30  A1001 (-3.5A) P30  A1001 (-4.3A) P30  A1001 (-4.8A) P30  A1001 ( 4.1A)	0.59A	51.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xuf	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	8 / 12	LEU A 616 VAL A 624 ALA A 642 LYS A 644 GLU A 661 GLY A 697 LEU A 818 PHE A 830	P30  A1001 (-4.0A) P30  A1001 ( 4.8A) P30  A1001 (-3.5A) P30  A1001 ( 4.0A) P30  A1001 (-3.1A) P30  A1001 (-3.5A) P30  A1001 (-4.3A) P30  A1001 ( 4.1A)	0.72A	51.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5a46	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens)	8 / 12	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLU A 531 VAL A 561 GLY A 567 LEU A 630	38O  A1769 (-3.2A) 38O  A1769 (-4.5A) 38O  A1769 (-3.6A) 38O  A1769 ( 3.1A) EDO  A1766 (-4.1A) 38O  A1769 (-4.3A) 38O  A1769 (-3.4A) 38O  A1769 (-4.6A)	0.60A	45.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5e8y	TGF-BETA RECEPTOR TYPE-2 (Homo sapiens)	6 / 12	VAL A 258 ALA A 275 LYS A 277 GLY A 331 LEU A 386 CYH A 396	STU  A 601 (-4.0A) STU  A 601 (-3.1A) STU  A 601 (-2.4A) STU  A 601 (-3.5A) STU  A 601 (-3.9A) STU  A 601 (-3.2A)	0.46A	27.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5f1z	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	7 / 12	LEU A 903 VAL A 911 ALA A 928 LYS A 930 GLU A 947 GLY A 984 LEU A1030	5U3  A1200 (-3.8A) 5U3  A1200 ( 4.4A) 5U3  A1200 (-3.5A) None None 5U3  A1200 (-3.2A) 5U3  A1200 (-4.4A)	0.53A	28.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5fm2	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET (Homo sapiens)	7 / 12	LEU A 730 VAL A 738 ALA A 756 LYS A 758 GLU A 775 LEU A 779 VAL A 804	PP1  A2012 (-4.6A) PP1  A2012 (-4.4A) PP1  A2012 (-3.2A) PP1  A2012 (-4.1A) PP1  A2012 (-3.5A) None PP1  A2012 (-4.5A)	0.64A	41.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5fm2	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET (Homo sapiens)	7 / 12	LEU A 730 VAL A 738 ALA A 756 LYS A 758 LEU A 779 VAL A 804 GLY A 810	PP1  A2012 (-4.6A) PP1  A2012 (-4.4A) PP1  A2012 (-3.2A) PP1  A2012 (-4.1A) None PP1  A2012 (-4.5A) PTR  A 809 (-2.4A)	0.65A	41.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5fm2	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET (Homo sapiens)	7 / 12	LEU A 730 VAL A 738 ALA A 756 LYS A 758 VAL A 804 GLY A 810 LEU A 881	PP1  A2012 (-4.6A) PP1  A2012 (-4.4A) PP1  A2012 (-3.2A) PP1  A2012 (-4.1A) PP1  A2012 (-4.5A) PTR  A 809 (-2.4A) PP1  A2012 (-4.6A)	0.61A	41.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	9 / 12	LEU A 599 VAL A 607 ALA A 625 LYS A 627 GLU A 644 GLY A 680 LEU A 825 CYH A 835 PHE A 837	748  A1001 (-3.8A) 748  A1001 ( 4.7A) 748  A1001 (-3.7A) 748  A1001 (-4.0A) 748  A1001 (-3.3A) 748  A1001 ( 4.0A) 748  A1001 (-4.3A) 748  A1001 (-4.5A) 748  A1001 (-3.7A)	0.45A	48.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5i3o	BMP-2-INDUCIBLE PROTEIN KINASE (Homo sapiens)	6 / 12	LEU A  57 VAL A  65 ALA A  77 GLY A 136 LEU A 187 CYH A 197	IDV  A 401 (-3.8A) IDV  A 401 (-4.6A) IDV  A 401 (-3.6A) IDV  A 401 (-3.4A) IDV  A 401 (-4.4A) IDV  A 401 (-3.6A)	0.44A	22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	6 / 12	VAL A  30 ALA A  43 LYS A  45 GLU A  61 GLY A  96 LEU A 143	6G2  A 901 ( 4.9A) 6G2  A 901 (-3.2A) 6G2  A 901 ( 3.9A) None 6G2  A 901 (-3.6A) 6G2  A 901 (-4.7A)	0.59A	21.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5j9z	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	6 / 12	LEU A 718 VAL A 726 ALA A 743 LYS A 745 GLY A 796 LEU A 844	6HJ  A1101 ( 4.6A) 6HJ  A1101 ( 4.7A) 6HJ  A1101 (-3.1A) 6HJ  A1101 (-4.2A) 6HJ  A1101 ( 4.5A) 6HJ  A1101 ( 4.8A)	0.53A	31.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5tur	SERINE/THREONINE-PRO TEIN KINASE PIM-1 (Homo sapiens)	7 / 12	LEU A  44 VAL A  52 ALA A  65 LYS A  67 GLU A  89 LEU A  93 LEU A 174	None 7LK  A 401 (-4.9A) 7LK  A 401 (-3.3A) None None None 7LK  A 401 (-4.8A)	0.52A	26.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5vil	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (Homo sapiens)	7 / 12	LEU A 686 VAL A 694 ALA A 707 LYS A 709 GLU A 725 GLY A 760 LEU A 810	9E1  A1001 (-3.7A) 9E1  A1001 ( 4.0A) 9E1  A1001 (-3.5A) 9E1  A1001 (-2.8A) None 9E1  A1001 (-3.4A) 9E1  A1001 (-4.5A)	0.43A	12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6c7y	TYROSINE-PROTEIN KINASE JAK1 (Homo sapiens)	7 / 12	LEU A 881 VAL A 889 ALA A 906 LYS A 908 GLU A 925 GLY A 962 LEU A1010	ADP  A1201 ( 4.5A) ADP  A1201 (-4.3A) ADP  A1201 (-3.4A) ADP  A1201 (-2.8A) None ADP  A1201 ( 4.1A) ADP  A1201 (-4.5A)	0.58A	13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6fek	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET (Homo sapiens)	6 / 12	LEU A 730 VAL A 738 ALA A 756 GLU A 775 LEU A 779 VAL A 804	ADN  A1104 ( 4.0A) ADN  A1104 (-4.4A) ADN  A1104 (-3.4A) None None ADN  A1104 ( 4.6A)	0.50A	23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6fek	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET (Homo sapiens)	7 / 12	LEU A 730 VAL A 738 ALA A 756 LEU A 779 VAL A 804 GLY A 810 LEU A 881	ADN  A1104 ( 4.0A) ADN  A1104 (-4.4A) ADN  A1104 (-3.4A) None ADN  A1104 ( 4.6A) ADN  A1104 ( 3.8A) ADN  A1104 (-4.3A)	0.58A	23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6fyl	DUAL SPECIFICITY PROTEIN KINASE CLK2 (Homo sapiens)	7 / 12	LEU A 169 VAL A 177 ALA A 191 LYS A 193 LEU A 212 GLY A 247 LEU A 297	3NG  A 501 (-3.9A) 3NG  A 501 ( 4.4A) 3NG  A 501 (-3.3A) 3NG  A 501 (-3.0A) None None None	1.04A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6fyv	DUAL SPECIFICITY PROTEIN KINASE CLK4 (Homo sapiens)	8 / 12	LEU A 167 VAL A 175 ALA A 189 LYS A 191 GLU A 206 LEU A 210 GLY A 245 LEU A 295	3NG  A 501 (-3.9A) 3NG  A 501 ( 4.3A) 3NG  A 501 (-3.5A) 3NG  A 501 (-2.7A) 3NG  A 501 ( 4.7A) None None None	1.15A	undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	1rjb	FL CYTOKINE RECEPTOR (Homo sapiens)	8 / 12	LEU A 616 VAL A 624 ALA A 642 LYS A 644 GLY A 697 ASN A 816 LEU A 818 ASP A 829	None	0.79A	37.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	1zlt	SERINE/THREONINE-PRO TEIN KINASE CHK1 (Homo sapiens)	8 / 12	LEU A  15 VAL A  23 ALA A  36 LYS A  38 GLY A  90 ASN A 135 LEU A 137 ASP A 148	HYM  A 400 (-4.2A) HYM  A 400 (-4.3A) HYM  A 400 (-3.5A) HYM  A 400 (-3.2A) None HYM  A 400 (-4.2A) HYM  A 400 (-4.5A) HYM  A 400 (-3.9A)	0.66A	25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2buj	SERINE/THREONINE-PRO TEIN KINASE 16 (Homo sapiens)	9 / 12	LEU A  26 VAL A  34 ALA A  47 LYS A  49 PHE A 100 GLY A 104 ASN A 153 LEU A 155 ASP A 166	STU  A1301 (-4.2A) STU  A1301 (-4.8A) STU  A1301 (-3.6A) STU  A1301 ( 4.0A) STU  A1301 (-4.5A) STU  A1301 ( 4.0A) None STU  A1301 ( 4.8A) None	0.64A	22.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	10 / 12	LEU X  17 VAL X  25 ALA X  37 LYS X  39 MET X  85 GLY X  88 ASN X 135 LEU X 137 ALA X 147 ASP X 148	STU  X 902 (-3.8A) STU  X 902 ( 4.8A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) None STU  X 902 (-3.5A) STU  X 902 ( 4.9A) STU  X 902 (-4.4A) STU  X 902 ( 4.1A) STU  X 902 (-3.6A)	0.47A	46.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2eu9	DUAL SPECIFICITY PROTEIN KINASE CLK3 (Homo sapiens)	9 / 12	LEU A 162 VAL A 170 ALA A 184 LYS A 186 GLY A 240 ASN A 288 LEU A 290 ALA A 319 ASP A 320	None	0.93A	25.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2h8h	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	9 / 12	LEU A 273 VAL A 281 ALA A 293 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403 ASP A 404	H8H  A 534 (-3.8A) H8H  A 534 (-4.4A) H8H  A 534 (-3.2A) None H8H  A 534 (-3.3A) H8H  A 534 ( 4.9A) H8H  A 534 (-4.5A) H8H  A 534 ( 4.0A) H8H  A 534 (-4.2A)	0.71A	33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	8 / 12	LEU A 273 ALA A 293 PHE A 340 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403	QUE  A   1 (-3.9A) QUE  A   1 (-3.5A) QUE  A   1 (-4.2A) None QUE  A   1 (-3.0A) None QUE  A   1 (-4.4A) QUE  A   1 ( 4.5A)	0.63A	33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	8 / 12	LEU A 273 VAL A 281 ALA A 293 PHE A 340 MET A 341 ASN A 391 LEU A 393 ALA A 403	QUE  A   1 (-3.9A) QUE  A   1 ( 4.8A) QUE  A   1 (-3.5A) QUE  A   1 (-4.2A) None None QUE  A   1 (-4.4A) QUE  A   1 ( 4.5A)	0.77A	33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	10 / 12	LEU A 251 VAL A 259 ALA A 271 LYS A 273 PHE A 318 MET A 319 GLY A 322 ASN A 369 LEU A 371 ALA A 381	1BM  A 499 ( 3.7A) 1BM  A 499 ( 4.8A) 1BM  A 499 (-3.6A) 1BM  A 499 (-3.8A) 1BM  A 499 (-4.1A) None 1BM  A 499 (-3.5A) 1BM  A 499 (-4.1A) 1BM  A 499 (-4.4A) 1BM  A 499 ( 3.7A)	0.80A	48.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	10 / 12	VAL A 259 ALA A 271 LYS A 273 PHE A 318 MET A 319 GLY A 322 ASN A 369 LEU A 371 ALA A 381 ASP A 382	1BM  A 499 ( 4.8A) 1BM  A 499 (-3.6A) 1BM  A 499 (-3.8A) 1BM  A 499 (-4.1A) None 1BM  A 499 (-3.5A) 1BM  A 499 (-4.1A) 1BM  A 499 (-4.4A) 1BM  A 499 ( 3.7A) 1BM  A 499 (-4.4A)	0.77A	48.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	10 / 12	LEU A 248 VAL A 256 ALA A 269 LYS A 271 PHE A 317 MET A 318 GLY A 321 LEU A 370 ALA A 380 ASP A 381	GIN  A 600 ( 4.6A) GIN  A 600 ( 4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-3.6A) GIN  A 600 (-4.3A) None None GIN  A 600 (-4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-4.9A)	0.57A	99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	10 / 12	LEU A 248 VAL A 256 ALA A 269 PHE A 317 MET A 318 GLY A 321 ASN A 368 LEU A 370 ALA A 380 ASP A 381	GIN  A 600 ( 4.6A) GIN  A 600 ( 4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-4.3A) None None None GIN  A 600 (-4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-4.9A)	0.65A	99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	9 / 12	LEU A 251 VAL A 259 ALA A 271 LYS A 273 MET A 319 GLY A 322 ASN A 369 LEU A 371 ALA A 381	None None 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.4A) 1N8  A 501 ( 4.4A) 1N8  A 501 ( 3.5A) None 1N8  A 501 ( 4.3A) 1N8  A 501 ( 3.3A)	0.74A	47.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2r4b	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	8 / 12	LEU A 724 VAL A 732 ALA A 749 MET A 799 GLY A 802 ASN A 848 LEU A 850 ASP A 861	GW7  A   1 ( 4.2A) GW7  A   1 ( 4.8A) GW7  A   1 (-3.3A) None GW7  A   1 (-3.6A) None GW7  A   1 (-4.2A) GW7  A   1 (-4.1A)	0.79A	35.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2v55	RHO-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	9 / 12	VAL A  90 ALA A 103 LYS A 105 MET A 156 GLY A 159 ASN A 203 LEU A 205 ALA A 215 ASP A 216	None ANP  A1480 ( 3.9A) ANP  A1480 (-3.4A) None None MG  A1481 (-3.5A) ANP  A1480 ( 4.7A) ANP  A1480 ( 4.1A) ANP  A1480 (-3.5A)	0.83A	22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2xik	SERINE/THREONINE PROTEIN KINASE 25 (Homo sapiens)	8 / 12	VAL A  34 ALA A  47 LYS A  49 GLY A 101 ASN A 145 LEU A 147 ALA A 157 ASP A 158	J60  A1294 ( 4.9A) J60  A1294 (-3.3A) None J60  A1294 ( 3.8A) None J60  A1294 (-4.8A) J60  A1294 ( 4.2A) J60  A1294 ( 4.6A)	0.71A	27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	9 / 12	LEU A  68 VAL A  76 ALA A  92 LYS A  94 PHE A 143 GLY A 147 ASN A 192 LEU A 194 ASP A 205	STU  A   1 (-3.8A) None STU  A   1 (-3.3A) STU  A   1 (-2.8A) STU  A   1 (-4.6A) STU  A   1 ( 3.9A) STU  A   1 (-4.3A) STU  A   1 (-4.6A) STU  A   1 ( 3.8A)	0.46A	25.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3b2t	FIBROBLAST GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	8 / 12	LEU A 487 VAL A 495 ALA A 515 LYS A 517 GLY A 570 ASN A 631 LEU A 633 ALA A 643	M33  A1996 (-4.0A) M33  A1996 ( 4.7A) M33  A1996 (-3.3A) M33  A1996 ( 4.5A) M33  A1996 ( 4.8A) None M33  A1996 (-4.5A) None	0.58A	41.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3c4f	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	9 / 12	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLY A 567 ASN A 628 LEU A 630 ALA A 640 ASP A 641	C4F  A   1 ( 3.9A) None C4F  A   1 (-3.3A) None None None C4F  A   1 (-4.6A) C4F  A   1 (-3.6A) C4F  A   1 (-4.5A)	0.95A	40.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	8 / 12	VAL A 209 ALA A 220 LYS A 222 MET A 269 GLY A 272 ASN A 319 LEU A 321 ASP A 332	None	0.67A	43.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3dko	EPHRIN TYPE-A RECEPTOR 7 (Homo sapiens)	8 / 12	VAL A 647 ALA A 663 LYS A 665 PHE A 713 MET A 714 GLY A 717 ASN A 763 LEU A 765	IHZ  A1001 ( 4.4A) IHZ  A1001 (-3.3A) IHZ  A1001 ( 4.5A) None None IHZ  A1001 ( 3.9A) None IHZ  A1001 (-4.6A)	0.76A	37.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3dtc	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9 (Homo sapiens)	8 / 12	VAL A 158 ALA A 169 LYS A 171 PHE A 222 GLY A 226 ASN A 273 LEU A 275 ASP A 294	VIN  A6331 (-4.7A) VIN  A6331 (-3.4A) None VIN  A6331 ( 4.8A) VIN  A6331 (-3.4A) VIN  A6331 ( 4.8A) VIN  A6331 (-4.5A) VIN  A6331 (-4.0A)	0.78A	35.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3hng	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	8 / 12	LEU A 833 VAL A 841 ALA A 859 LYS A 861 GLY A 915 ASN A1027 LEU A1029 ASP A1040	8ST  A2001 ( 4.7A) 8ST  A2001 ( 4.6A) 8ST  A2001 ( 3.8A) 8ST  A2001 (-4.0A) None None None None	0.69A	33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3kul	EPHRIN TYPE-A RECEPTOR 8 (Homo sapiens)	8 / 12	VAL A 649 ALA A 665 LYS A 667 MET A 716 GLY A 719 ASN A 765 LEU A 767 ASP A 778	None None None None GOL  A 403 (-3.4A) None None None	0.62A	33.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3nuu	PKB-LIKE (Homo sapiens)	8 / 12	LEU A  88 VAL A  96 ALA A 109 LYS A 111 GLY A 165 ASN A 210 LEU A 212 ASP A 223	JOZ  A 361 (-4.1A) JOZ  A 361 ( 4.7A) JOZ  A 361 (-3.4A) SO4  A   5 (-2.8A) None None None SO4  A   5 ( 4.5A)	0.61A	25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	8 / 12	LEU A 192 VAL A 200 ALA A 213 MET A 266 GLY A 269 ASN A 316 LEU A 318 ASP A 329	AMP  A 577 ( 4.3A) AMP  A 577 (-4.3A) AMP  A 577 (-3.4A) None None AMP  A 577 (-4.2A) AMP  A 577 (-4.8A) AMP  A 577 (-4.0A)	0.68A	19.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	8 / 12	LEU A 726 VAL A 734 ALA A 751 MET A 801 GLY A 804 ASN A 850 LEU A 852 ASP A 863	03Q  A   1 (-3.8A) 03Q  A   1 (-4.5A) 03Q  A   1 (-3.1A) None 03Q  A   1 ( 3.9A) 03Q  A   1 (-4.2A) 03Q  A   1 (-4.4A) 03Q  A   1 (-4.0A)	0.70A	33.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3qfv	CDC42BPB PROTEIN (Homo sapiens)	8 / 12	VAL A  90 ALA A 103 LYS A 105 GLY A 159 ASN A 205 LEU A 207 ALA A 217 ASP A 218	NM7  A 416 (-3.7A) NM7  A 416 ( 3.7A) EDO  A 417 (-3.5A) None None NM7  A 416 ( 4.2A) NM7  A 416 ( 4.5A) EDO  A 417 (-3.7A)	0.78A	24.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3tt0	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	9 / 12	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLY A 567 ASN A 628 LEU A 630 ALA A 640 ASP A 641	07J  A   1 ( 4.3A) 07J  A   1 (-4.0A) 07J  A   1 (-3.5A) 07J  A   1 (-4.5A) 07J  A   1 (-3.7A) None 07J  A   1 ( 4.4A) 07J  A   1 (-3.2A) 07J  A   1 (-4.7A)	0.78A	34.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	10 / 12	LEU A 361 VAL A 369 ALA A 382 LYS A 384 PHE A 435 GLY A 439 ASN A 484 LEU A 486 ALA A 496 ASP A 497	07U  A   1 ( 4.8A) 07U  A   1 (-4.8A) 07U  A   1 (-3.3A) 07U  A   1 (-3.0A) None None None 07U  A   1 (-4.3A) 07U  A   1 ( 4.0A) 07U  A   1 (-3.6A)	0.75A	24.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3vid	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	8 / 12	LEU A 840 VAL A 848 ALA A 866 LYS A 868 PHE A 918 GLY A 922 ASN A1033 LEU A1035	4TT  A2001 ( 4.0A) 4TT  A2001 ( 4.5A) 4TT  A2001 (-3.5A) None 4TT  A2001 (-4.5A) 4TT  A2001 (-3.7A) None 4TT  A2001 (-4.8A)	0.70A	34.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3w18	AURORA KINASE A (Homo sapiens)	8 / 12	LEU A 139 VAL A 147 ALA A 160 LYS A 162 GLY A 216 ASN A 261 LEU A 263 ALA A 273	N13  A 501 (-3.7A) N13  A 501 ( 4.7A) N13  A 501 ( 4.1A) N13  A 501 (-2.9A) N13  A 501 (-3.5A) None N13  A 501 (-4.5A) N13  A 501 ( 3.8A)	0.80A	27.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	9 / 12	LEU A 840 VAL A 848 ALA A 866 LYS A 868 PHE A 918 GLY A 922 ASN A1033 LEU A1035 ASP A1046	LEV  A1201 ( 3.8A) LEV  A1201 ( 4.9A) LEV  A1201 (-3.5A) None LEV  A1201 (-4.7A) LEV  A1201 (-3.6A) GOL  A1210 (-3.6A) LEV  A1201 (-4.8A) GOL  A1210 ( 3.4A)	0.77A	37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	8 / 12	VAL A1959 ALA A1978 LYS A1980 MET A2029 GLY A2032 ASN A2084 LEU A2086 ASP A2102	None VGH  A3000 (-3.4A) VGH  A3000 ( 4.7A) None VGH  A3000 (-3.5A) None VGH  A3000 (-4.3A) None	0.78A	39.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	3zfx	EPHRIN TYPE-B RECEPTOR 1 (Homo sapiens)	8 / 12	VAL A 633 ALA A 649 PHE A 699 MET A 700 GLY A 703 ASN A 749 LEU A 751 ASP A 762	None	0.63A	40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4at3	BDNF/NT-3 GROWTH FACTORS RECEPTOR (Homo sapiens)	8 / 12	LEU A 560 VAL A 568 ALA A 586 MET A 636 GLY A 639 ASN A 697 LEU A 699 ASP A 710	LTI  A1839 ( 4.2A) None LTI  A1839 (-3.3A) None LTI  A1839 (-3.4A) None LTI  A1839 (-4.2A) None	0.70A	36.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4aw5	EPHRIN TYPE-B RECEPTOR 4 (Homo sapiens)	9 / 12	VAL A 105 ALA A 121 LYS A 123 PHE A 171 MET A 172 GLY A 175 ASN A 221 LEU A 223 ASP A 234	30K  A1365 ( 4.6A) 30K  A1365 (-3.2A) 30K  A1365 (-3.8A) 30K  A1365 (-4.4A) None 30K  A1365 (-3.5A) 30K  A1365 (-4.4A) 30K  A1365 (-4.5A) 30K  A1365 (-3.3A)	0.73A	39.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4bc6	SERINE/THREONINE-PRO TEIN KINASE 10 (Homo sapiens)	9 / 12	LEU A  42 VAL A  50 ALA A  63 LYS A  65 PHE A 112 GLY A 116 ASN A 162 LEU A 164 ALA A 174	XZN  A1317 (-3.6A) XZN  A1317 ( 4.7A) XZN  A1317 (-3.5A) XZN  A1317 (-4.1A) XZN  A1317 (-4.5A) XZN  A1317 ( 3.7A) None XZN  A1317 (-4.7A) XZN  A1317 ( 4.3A)	0.93A	30.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	8 / 12	LEU A 616 VAL A 624 ALA A 653 LYS A 655 MET A 704 ASN A 771 LEU A 773 ALA A 783	None DI1  A1000 (-4.8A) DI1  A1000 (-3.6A) DI1  A1000 (-3.9A) None None DI1  A1000 (-4.5A) DI1  A1000 (-3.7A)	0.67A	37.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	8 / 12	VAL A 624 ALA A 653 LYS A 655 MET A 704 GLY A 707 ASN A 771 LEU A 773 ALA A 783	DI1  A1000 (-4.8A) DI1  A1000 (-3.6A) DI1  A1000 (-3.9A) None None None DI1  A1000 (-4.5A) DI1  A1000 (-3.7A)	0.61A	37.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4crs	SERINE/THREONINE-PRO TEIN KINASE N2 (Homo sapiens)	9 / 12	LEU A 663 VAL A 671 ALA A 684 LYS A 686 GLY A 743 ASN A 787 LEU A 789 ALA A 799 ASP A 800	AGS  A1985 (-4.2A) AGS  A1985 (-4.6A) AGS  A1985 (-3.5A) AGS  A1985 (-3.0A) None MG  A1986 ( 3.2A) AGS  A1985 (-4.8A) AGS  A1985 ( 4.5A) AGS  A1985 ( 3.3A)	0.64A	26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4eut	SERINE/THREONINE-PRO TEIN KINASE TBK1 (Homo sapiens)	8 / 12	LEU A  15 VAL A  23 ALA A  36 LYS A  38 PHE A  88 GLY A  92 ASN A 140 ASP A 157	BX7  A 401 (-3.7A) BX7  A 401 (-4.4A) BX7  A 401 (-3.4A) BX7  A 401 ( 4.0A) BX7  A 401 ( 4.6A) BX7  A 401 (-3.5A) None BX7  A 401 ( 3.7A)	0.68A	23.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLY A 908 ASN A 954 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 ( 3.8A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.54A	35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4k11	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	8 / 12	LEU A 273 VAL A 281 ALA A 293 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403	0J9  A 601 (-4.0A) 0J9  A 601 (-4.4A) 0J9  A 601 (-3.3A) None 0J9  A 601 ( 4.1A) None 0J9  A 601 (-4.5A) 0J9  A 601 (-3.5A)	0.79A	33.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4k33	FIBROBLAST GROWTH FACTOR RECEPTOR 3 (Homo sapiens)	8 / 12	LEU A 478 VAL A 486 ALA A 506 GLY A 561 ASN A 622 LEU A 624 ALA A 634 ASP A 635	ACP  A 801 (-3.8A) ACP  A 801 (-4.2A) ACP  A 801 (-3.3A) ACP  A 801 ( 4.6A) MG  A 802 ( 2.4A) ACP  A 801 (-4.4A) None MG  A 802 ( 3.0A)	0.66A	38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4k33	FIBROBLAST GROWTH FACTOR RECEPTOR 3 (Homo sapiens)	8 / 12	LEU A 478 VAL A 486 ALA A 506 LYS A 508 GLY A 561 LEU A 624 ALA A 634 ASP A 635	ACP  A 801 (-3.8A) ACP  A 801 (-4.2A) ACP  A 801 (-3.3A) ACP  A 801 (-2.7A) ACP  A 801 ( 4.6A) ACP  A 801 (-4.4A) None MG  A 802 ( 3.0A)	0.78A	38.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4o27	SERINE/THREONINE-PRO TEIN KINASE 24 (Homo sapiens)	8 / 12	VAL B  38 ALA B  51 LYS B  53 GLY B 105 ASN B 149 LEU B 151 ALA B 161 ASP B 162	ADP  B 500 (-4.5A) ADP  B 500 (-3.3A) ADP  B 500 (-3.1A) None MN  B 501 ( 3.1A) ADP  B 500 (-4.7A) None ADP  B 500 ( 3.4A)	0.66A	28.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	8 / 12	LEU A  46 VAL A  54 ALA A  67 LYS A  69 GLY A 128 ASN A 178 LEU A 180 ASP A 191	SIN  A 401 ( 3.9A) None SIN  A 401 ( 3.7A) None SIN  A 401 (-3.5A) None SIN  A 401 ( 4.5A) None	0.60A	24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4oli	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	8 / 12	LEU A 903 VAL A 911 ALA A 928 LYS A 930 GLY A 984 ASN A1028 LEU A1030 ASP A1041	2TT  A1202 (-3.5A) 2TT  A1202 (-4.5A) 2TT  A1202 ( 3.9A) None 2TT  A1202 (-3.4A) 2TT  A1202 (-4.5A) 2TT  A1202 (-4.4A) 2TT  A1202 (-4.6A)	0.73A	19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4q9z	HUMAN PROTEIN KINASE C THETA (Homo sapiens)	8 / 12	LEU A 386 VAL A 394 ALA A 407 LYS A 409 GLY A 464 ASN A 509 LEU A 511 ALA A 521	PZW  A 801 (-3.9A) PZW  A 801 (-4.6A) PZW  A 801 (-3.5A) None None PZW  A 801 (-4.4A) PZW  A 801 (-4.8A) PZW  A 801 ( 4.6A)	0.79A	27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4rew	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (Homo sapiens)	9 / 12	LEU A  24 VAL A  32 ALA A  45 LYS A  47 GLY A 101 ASN A 146 LEU A 148 ALA A 158 ASP A 159	STU  A 601 (-3.7A) STU  A 601 ( 4.8A) STU  A 601 (-3.2A) STU  A 601 ( 3.7A) STU  A 601 ( 3.8A) STU  A 601 (-4.2A) STU  A 601 (-4.2A) STU  A 601 ( 3.8A) STU  A 601 (-3.7A)	0.76A	20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4wsq	AP2-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	9 / 12	LEU A  52 VAL A  60 ALA A  72 LYS A  74 PHE A 128 GLY A 132 ASN A 181 LEU A 183 ASP A 194	KSA  A 405 ( 4.0A) KSA  A 405 ( 4.9A) KSA  A 405 (-3.2A) None KSA  A 405 (-4.8A) KSA  A 405 (-3.5A) KSA  A 405 (-4.0A) KSA  A 405 (-4.6A) ZN  A 403 ( 2.6A)	0.74A	23.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4xcu	FIBROBLAST GROWTH FACTOR RECEPTOR 4 (Homo sapiens)	8 / 12	LEU A 473 VAL A 481 ALA A 501 LYS A 503 GLY A 556 ASN A 617 LEU A 619 ALA A 629	40M  A1002 ( 4.6A) 40M  A1002 ( 4.5A) 40M  A1002 ( 4.1A) 40M  A1002 (-4.0A) 40M  A1002 ( 3.7A) None 40M  A1002 (-4.5A) 40M  A1002 (-3.0A)	0.74A	40.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	VAL B 275 ALA B 288 LYS B 290 PHE B 336 MET B 337 ASN B 387 LEU B 389 ALA B 399	1N1  B 601 ( 4.9A) 1N1  B 601 (-3.5A) 1N1  B 601 (-4.6A) 1N1  B 601 ( 4.2A) None None 1N1  B 601 (-4.3A) 1N1  B 601 (-3.5A)	0.73A	99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	VAL B 275 ALA B 288 PHE B 336 MET B 337 GLY B 340 ASN B 387 LEU B 389 ALA B 399	1N1  B 601 ( 4.9A) 1N1  B 601 (-3.5A) 1N1  B 601 ( 4.2A) None 1N1  B 601 (-3.5A) None 1N1  B 601 (-4.3A) 1N1  B 601 (-3.5A)	0.58A	99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	5a46	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens)	8 / 12	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLY A 567 ASN A 628 ALA A 640 ASP A 641	38O  A1769 (-3.2A) 38O  A1769 (-4.5A) 38O  A1769 (-3.6A) 38O  A1769 ( 3.1A) 38O  A1769 (-3.4A) None EDO  A1766 ( 4.4A) 38O  A1769 (-4.0A)	0.70A	40.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	5a46	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens)	8 / 12	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLY A 567 ASN A 628 LEU A 630 ALA A 640	38O  A1769 (-3.2A) 38O  A1769 (-4.5A) 38O  A1769 (-3.6A) 38O  A1769 ( 3.1A) 38O  A1769 (-3.4A) None 38O  A1769 (-4.6A) EDO  A1766 ( 4.4A)	0.59A	40.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	5f1z	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	8 / 12	LEU A 903 VAL A 911 ALA A 928 LYS A 930 GLY A 984 ASN A1028 LEU A1030 ASP A1041	5U3  A1200 (-3.8A) 5U3  A1200 ( 4.4A) 5U3  A1200 (-3.5A) None 5U3  A1200 (-3.2A) 5U3  A1200 (-4.7A) 5U3  A1200 (-4.4A) 5U3  A1200 ( 4.9A)	0.75A	32.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	5iso	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 (Homo sapiens)	9 / 12	LEU A  22 VAL A  30 ALA A  43 LYS A  45 GLY A  99 ASN A 144 LEU A 146 ALA A 156 ASP A 157	STU  A 601 (-4.1A) STU  A 601 (-4.8A) STU  A 601 (-3.3A) STU  A 601 ( 4.4A) STU  A 601 ( 4.0A) STU  A 601 (-4.3A) STU  A 601 (-4.5A) STU  A 601 (-3.5A) STU  A 601 (-3.5A)	0.78A	19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	9 / 12	VAL A  30 ALA A  43 LYS A  45 PHE A  92 GLY A  96 ASN A 141 LEU A 143 ALA A 153 ASP A 154	6G2  A 901 ( 4.9A) 6G2  A 901 (-3.2A) 6G2  A 901 ( 3.9A) 6G2  A 901 (-4.1A) 6G2  A 901 (-3.6A) None 6G2  A 901 (-4.7A) 6G2  A 901 ( 4.2A) 6G2  A 901 (-3.4A)	0.65A	24.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	8 / 12	VAL A 601 ALA A 617 PHE A 673 MET A 674 GLY A 677 ASN A 728 ALA A 740 ASP A 741	7AE  A1000 ( 4.9A) 7AE  A1000 (-3.3A) 7AE  A1000 (-4.1A) None 7AE  A1000 ( 3.7A) 7AE  A1000 (-4.7A) 7AE  A1000 ( 3.7A) 7AE  A1000 (-4.4A)	0.60A	44.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	5u6b	TYROSINE-PROTEIN KINASE RECEPTOR UFO (Homo sapiens)	9 / 12	LEU A 542 VAL A 550 ALA A 565 LYS A 567 PHE A 622 MET A 623 GLY A 626 ASN A 677 ASP A 690	7YS  A9001 (-4.1A) 7YS  A9001 (-4.2A) 7YS  A9001 (-3.3A) None 7YS  A9001 (-4.3A) 7YS  A9001 (-4.7A) 7YS  A9001 (-3.4A) None None	0.75A	42.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	5u6b	TYROSINE-PROTEIN KINASE RECEPTOR UFO (Homo sapiens)	9 / 12	VAL A 550 ALA A 565 LYS A 567 PHE A 622 MET A 623 GLY A 626 ASN A 677 ALA A 689 ASP A 690	7YS  A9001 (-4.2A) 7YS  A9001 (-3.3A) None 7YS  A9001 (-4.3A) 7YS  A9001 (-4.7A) 7YS  A9001 (-3.4A) None 7YS  A9001 (-3.4A) None	0.72A	42.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	5u7q	RHO-ASSOCIATED PROTEIN KINASE 2 (Homo sapiens)	9 / 12	VAL A 106 ALA A 119 LYS A 121 MET A 172 GLY A 175 ASN A 219 LEU A 221 ALA A 231 ASP A 232	None	0.62A	22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	5vil	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (Homo sapiens)	8 / 12	LEU A 686 VAL A 694 ALA A 707 LYS A 709 GLY A 760 ASN A 808 LEU A 810 ASP A 822	9E1  A1001 (-3.7A) 9E1  A1001 ( 4.0A) 9E1  A1001 (-3.5A) 9E1  A1001 (-2.8A) 9E1  A1001 (-3.4A) 9E1  A1001 ( 4.0A) 9E1  A1001 (-4.5A) 9E1  A1001 (-3.6A)	0.68A	14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	5w5j	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2 (Homo sapiens)	8 / 12	LEU A  24 VAL A  32 ALA A  45 MET A  98 GLY A 101 ASN A 151 LEU A 153 ALA A 163	9WS  A 401 ( 4.2A) 9WS  A 401 ( 4.6A) 9WS  A 401 (-3.3A) None 9WS  A 401 ( 4.3A) None 9WS  A 401 (-4.6A) 9WS  A 401 ( 4.0A)	0.63A	27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	6b3e	CYCLIN-DEPENDENT KINASE 12 (Homo sapiens)	8 / 12	VAL A 741 ALA A 754 LYS A 756 MET A 816 ASN A 864 LEU A 866 ALA A 876 ASP A 877	None CJM  A1102 (-3.1A) None None MG  A1101 ( 4.4A) CJM  A1102 (-4.4A) CJM  A1102 (-3.6A) MG  A1101 (-2.5A)	0.52A	15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	6c7y	TYROSINE-PROTEIN KINASE JAK1 (Homo sapiens)	8 / 12	LEU A 881 VAL A 889 ALA A 906 LYS A 908 PHE A 958 GLY A 962 LEU A1010 ASP A1021	ADP  A1201 ( 4.5A) ADP  A1201 (-4.3A) ADP  A1201 (-3.4A) ADP  A1201 (-2.8A) None ADP  A1201 ( 4.1A) ADP  A1201 (-4.5A) MG  A1203 (-1.8A)	0.62A	13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	6c7y	TYROSINE-PROTEIN KINASE JAK1 (Homo sapiens)	8 / 12	LEU A 881 VAL A 889 ALA A 906 PHE A 958 GLY A 962 ASN A1008 LEU A1010 ASP A1021	ADP  A1201 ( 4.5A) ADP  A1201 (-4.3A) ADP  A1201 (-3.4A) None ADP  A1201 ( 4.1A) MG  A1202 ( 2.5A) ADP  A1201 (-4.5A) MG  A1203 (-1.8A)	0.61A	13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	6ccf	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 1 (Homo sapiens)	8 / 12	VAL A 142 ALA A 155 LYS A 157 GLY A 236 ASN A 280 LEU A 282 ALA A 292 ASP A 293	H1N  A 501 (-4.4A) H1N  A 501 (-3.4A) H1N  A 501 (-2.8A) H1N  A 501 (-3.6A) H1N  A 501 (-4.5A) H1N  A 501 (-4.8A) H1N  A 501 ( 3.9A) H1N  A 501 (-3.5A)	0.52A	13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	VAL A 179 ALA A 192 LYS A 194 GLY A 273 ASN A 317 LEU A 319 ALA A 329 ASP A 330	F6J  A 501 (-4.6A) F6J  A 501 (-3.4A) F6J  A 501 (-2.9A) F6J  A 501 ( 3.7A) F6J  A 501 ( 4.7A) F6J  A 501 (-4.5A) F6J  A 501 ( 4.0A) F6J  A 501 (-3.8A)	0.63A	14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	6f3d	INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 (Homo sapiens)	8 / 12	VAL A 200 ALA A 211 LYS A 213 MET A 265 GLY A 268 ASN A 316 LEU A 318 ASP A 329	CJT  A 502 ( 4.8A) CJT  A 502 (-3.4A) CJT  A 502 (-3.0A) CJT  A 502 (-4.9A) CJT  A 502 ( 4.3A) None CJT  A 502 (-4.7A) CJT  A 502 ( 4.0A)	0.78A	15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2buj	SERINE/THREONINE-PRO TEIN KINASE 16 (Homo sapiens)	9 / 12	LEU A  26 VAL A  34 ALA A  47 LYS A  49 PHE A 100 GLY A 104 ASN A 153 LEU A 155 ASP A 166	STU  A1301 (-4.2A) STU  A1301 (-4.8A) STU  A1301 (-3.6A) STU  A1301 ( 4.0A) STU  A1301 (-4.5A) STU  A1301 ( 4.0A) None STU  A1301 ( 4.8A) None	0.70A	22.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	8 / 12	LEU X  17 VAL X  25 ALA X  37 LYS X  39 MET X  85 GLY X  88 LEU X 137 ALA X 147	STU  X 902 (-3.8A) STU  X 902 ( 4.8A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) None STU  X 902 (-3.5A) STU  X 902 (-4.4A) STU  X 902 ( 4.1A)	0.53A	46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	9 / 12	LEU X  17 VAL X  25 ALA X  37 MET X  85 GLY X  88 ASN X 135 LEU X 137 ALA X 147 ASP X 148	STU  X 902 (-3.8A) STU  X 902 ( 4.8A) STU  X 902 (-3.1A) None STU  X 902 (-3.5A) STU  X 902 ( 4.9A) STU  X 902 (-4.4A) STU  X 902 ( 4.1A) STU  X 902 (-3.6A)	0.41A	46.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2eu9	DUAL SPECIFICITY PROTEIN KINASE CLK3 (Homo sapiens)	8 / 12	LEU A 162 VAL A 170 ALA A 184 LYS A 186 ASN A 288 LEU A 290 ALA A 319 ASP A 320	None	0.71A	25.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2h8h	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	9 / 12	LEU A 273 VAL A 281 ALA A 293 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403 ASP A 404	H8H  A 534 (-3.8A) H8H  A 534 (-4.4A) H8H  A 534 (-3.2A) None H8H  A 534 (-3.3A) H8H  A 534 ( 4.9A) H8H  A 534 (-4.5A) H8H  A 534 ( 4.0A) H8H  A 534 (-4.2A)	0.74A	33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	9 / 12	LEU A 273 VAL A 281 ALA A 293 LYS A 295 PHE A 340 MET A 341 GLY A 344 LEU A 393 ALA A 403	QUE  A   1 (-3.9A) QUE  A   1 ( 4.8A) QUE  A   1 (-3.5A) None QUE  A   1 (-4.2A) None QUE  A   1 (-3.0A) QUE  A   1 (-4.4A) QUE  A   1 ( 4.5A)	0.97A	33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	9 / 12	LEU A 273 VAL A 281 ALA A 293 PHE A 340 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403	QUE  A   1 (-3.9A) QUE  A   1 ( 4.8A) QUE  A   1 (-3.5A) QUE  A   1 (-4.2A) None QUE  A   1 (-3.0A) None QUE  A   1 (-4.4A) QUE  A   1 ( 4.5A)	0.75A	33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	11 / 12	LEU A 251 VAL A 259 ALA A 271 LYS A 273 PHE A 318 MET A 319 GLY A 322 ASN A 369 LEU A 371 ALA A 381 ASP A 382	1BM  A 499 ( 3.7A) 1BM  A 499 ( 4.8A) 1BM  A 499 (-3.6A) 1BM  A 499 (-3.8A) 1BM  A 499 (-4.1A) None 1BM  A 499 (-3.5A) 1BM  A 499 (-4.1A) 1BM  A 499 (-4.4A) 1BM  A 499 ( 3.7A) 1BM  A 499 (-4.4A)	0.81A	48.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	10 / 12	LEU A 248 VAL A 256 ALA A 269 LYS A 271 PHE A 317 MET A 318 GLY A 321 LEU A 370 ALA A 380 ASP A 381	GIN  A 600 ( 4.6A) GIN  A 600 ( 4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-3.6A) GIN  A 600 (-4.3A) None None GIN  A 600 (-4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-4.9A)	0.59A	99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	10 / 12	LEU A 248 VAL A 256 ALA A 269 PHE A 317 MET A 318 GLY A 321 ASN A 368 LEU A 370 ALA A 380 ASP A 381	GIN  A 600 ( 4.6A) GIN  A 600 ( 4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-4.3A) None None None GIN  A 600 (-4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-4.9A)	0.62A	99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	8 / 12	LEU A 251 VAL A 259 ALA A 271 LYS A 273 MET A 319 GLY A 322 LEU A 371 ALA A 381	None None 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.4A) 1N8  A 501 ( 4.4A) 1N8  A 501 ( 3.5A) 1N8  A 501 ( 4.3A) 1N8  A 501 ( 3.3A)	0.82A	47.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	8 / 12	LEU A 251 VAL A 259 ALA A 271 MET A 319 GLY A 322 ASN A 369 LEU A 371 ALA A 381	None None 1N8  A 501 ( 3.4A) 1N8  A 501 ( 4.4A) 1N8  A 501 ( 3.5A) None 1N8  A 501 ( 4.3A) 1N8  A 501 ( 3.3A)	0.80A	47.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2v55	RHO-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	8 / 12	VAL A  90 ALA A 103 LYS A 105 MET A 156 GLY A 159 LEU A 205 ALA A 215 ASP A 216	None ANP  A1480 ( 3.9A) ANP  A1480 (-3.4A) None None ANP  A1480 ( 4.7A) ANP  A1480 ( 4.1A) ANP  A1480 (-3.5A)	0.90A	22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2v55	RHO-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	8 / 12	VAL A  90 ALA A 103 MET A 156 GLY A 159 ASN A 203 LEU A 205 ALA A 215 ASP A 216	None ANP  A1480 ( 3.9A) None None MG  A1481 (-3.5A) ANP  A1480 ( 4.7A) ANP  A1480 ( 4.1A) ANP  A1480 (-3.5A)	0.80A	22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2xik	SERINE/THREONINE PROTEIN KINASE 25 (Homo sapiens)	8 / 12	VAL A  34 ALA A  47 LYS A  49 GLY A 101 ASN A 145 LEU A 147 ALA A 157 ASP A 158	J60  A1294 ( 4.9A) J60  A1294 (-3.3A) None J60  A1294 ( 3.8A) None J60  A1294 (-4.8A) J60  A1294 ( 4.2A) J60  A1294 ( 4.6A)	0.76A	27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	8 / 12	LEU A  68 VAL A  76 ALA A  92 PHE A 143 GLY A 147 ASN A 192 LEU A 194 ASP A 205	STU  A   1 (-3.8A) None STU  A   1 (-3.3A) STU  A   1 (-4.6A) STU  A   1 ( 3.9A) STU  A   1 (-4.3A) STU  A   1 (-4.6A) STU  A   1 ( 3.8A)	0.48A	25.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3b2t	FIBROBLAST GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	8 / 12	LEU A 487 VAL A 495 ALA A 515 LYS A 517 GLY A 570 ASN A 631 LEU A 633 ALA A 643	M33  A1996 (-4.0A) M33  A1996 ( 4.7A) M33  A1996 (-3.3A) M33  A1996 ( 4.5A) M33  A1996 ( 4.8A) None M33  A1996 (-4.5A) None	0.54A	41.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3c4f	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	9 / 12	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLY A 567 ASN A 628 LEU A 630 ALA A 640 ASP A 641	C4F  A   1 ( 3.9A) None C4F  A   1 (-3.3A) None None None C4F  A   1 (-4.6A) C4F  A   1 (-3.6A) C4F  A   1 (-4.5A)	0.99A	40.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3dko	EPHRIN TYPE-A RECEPTOR 7 (Homo sapiens)	8 / 12	VAL A 647 ALA A 663 LYS A 665 PHE A 713 MET A 714 GLY A 717 ASN A 763 LEU A 765	IHZ  A1001 ( 4.4A) IHZ  A1001 (-3.3A) IHZ  A1001 ( 4.5A) None None IHZ  A1001 ( 3.9A) None IHZ  A1001 (-4.6A)	0.77A	37.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3dtc	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9 (Homo sapiens)	8 / 12	VAL A 158 ALA A 169 LYS A 171 PHE A 222 GLY A 226 ASN A 273 LEU A 275 ASP A 294	VIN  A6331 (-4.7A) VIN  A6331 (-3.4A) None VIN  A6331 ( 4.8A) VIN  A6331 (-3.4A) VIN  A6331 ( 4.8A) VIN  A6331 (-4.5A) VIN  A6331 (-4.0A)	0.70A	35.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3hng	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	8 / 12	LEU A 833 VAL A 841 ALA A 859 LYS A 861 GLY A 915 ASN A1027 LEU A1029 ASP A1040	8ST  A2001 ( 4.7A) 8ST  A2001 ( 4.6A) 8ST  A2001 ( 3.8A) 8ST  A2001 (-4.0A) None None None None	0.76A	33.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	8 / 12	LEU A 192 VAL A 200 ALA A 213 MET A 266 GLY A 269 ASN A 316 LEU A 318 ASP A 329	AMP  A 577 ( 4.3A) AMP  A 577 (-4.3A) AMP  A 577 (-3.4A) None None AMP  A 577 (-4.2A) AMP  A 577 (-4.8A) AMP  A 577 (-4.0A)	0.67A	19.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	8 / 12	LEU A 726 VAL A 734 ALA A 751 MET A 801 GLY A 804 ASN A 850 LEU A 852 ASP A 863	03Q  A   1 (-3.8A) 03Q  A   1 (-4.5A) 03Q  A   1 (-3.1A) None 03Q  A   1 ( 3.9A) 03Q  A   1 (-4.2A) 03Q  A   1 (-4.4A) 03Q  A   1 (-4.0A)	0.70A	33.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3tt0	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	8 / 12	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLY A 567 ASN A 628 LEU A 630 ALA A 640	07J  A   1 ( 4.3A) 07J  A   1 (-4.0A) 07J  A   1 (-3.5A) 07J  A   1 (-4.5A) 07J  A   1 (-3.7A) None 07J  A   1 ( 4.4A) 07J  A   1 (-3.2A)	0.73A	34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3tt0	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	8 / 12	LEU A 484 VAL A 492 LYS A 514 GLY A 567 ASN A 628 LEU A 630 ALA A 640 ASP A 641	07J  A   1 ( 4.3A) 07J  A   1 (-4.0A) 07J  A   1 (-4.5A) 07J  A   1 (-3.7A) None 07J  A   1 ( 4.4A) 07J  A   1 (-3.2A) 07J  A   1 (-4.7A)	0.89A	34.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	8 / 12	LEU A 361 VAL A 369 ALA A 382 LYS A 384 PHE A 435 GLY A 439 LEU A 486 ALA A 496	07U  A   1 ( 4.8A) 07U  A   1 (-4.8A) 07U  A   1 (-3.3A) 07U  A   1 (-3.0A) None None 07U  A   1 (-4.3A) 07U  A   1 ( 4.0A)	0.75A	24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	9 / 12	LEU A 361 VAL A 369 ALA A 382 PHE A 435 GLY A 439 ASN A 484 LEU A 486 ALA A 496 ASP A 497	07U  A   1 ( 4.8A) 07U  A   1 (-4.8A) 07U  A   1 (-3.3A) None None None 07U  A   1 (-4.3A) 07U  A   1 ( 4.0A) 07U  A   1 (-3.6A)	0.75A	24.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3v5q	NT-3 GROWTH FACTOR RECEPTOR (Homo sapiens)	8 / 12	LEU A 544 VAL A 552 ALA A 570 LYS A 572 MET A 620 GLY A 623 ASN A 684 LEU A 686	0F4  A 902 ( 4.2A) None 0F4  A 902 (-3.2A) 0F4  A 902 (-4.0A) None 0F4  A 902 (-3.4A) None 0F4  A 902 (-4.5A)	0.97A	36.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3vid	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	8 / 12	LEU A 840 VAL A 848 ALA A 866 LYS A 868 PHE A 918 GLY A 922 ASN A1033 LEU A1035	4TT  A2001 ( 4.0A) 4TT  A2001 ( 4.5A) 4TT  A2001 (-3.5A) None 4TT  A2001 (-4.5A) 4TT  A2001 (-3.7A) None 4TT  A2001 (-4.8A)	0.67A	34.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3w18	AURORA KINASE A (Homo sapiens)	8 / 12	LEU A 139 VAL A 147 ALA A 160 LYS A 162 GLY A 216 ASN A 261 LEU A 263 ALA A 273	N13  A 501 (-3.7A) N13  A 501 ( 4.7A) N13  A 501 ( 4.1A) N13  A 501 (-2.9A) N13  A 501 (-3.5A) None N13  A 501 (-4.5A) N13  A 501 ( 3.8A)	0.83A	27.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	9 / 12	LEU A 840 VAL A 848 ALA A 866 LYS A 868 PHE A 918 GLY A 922 ASN A1033 LEU A1035 ASP A1046	LEV  A1201 ( 3.8A) LEV  A1201 ( 4.9A) LEV  A1201 (-3.5A) None LEV  A1201 (-4.7A) LEV  A1201 (-3.6A) GOL  A1210 (-3.6A) LEV  A1201 (-4.8A) GOL  A1210 ( 3.4A)	0.78A	37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	8 / 12	LEU A1951 VAL A1959 ALA A1978 LYS A1980 MET A2029 GLY A2032 LEU A2086 ASP A2102	VGH  A3000 ( 4.4A) None VGH  A3000 (-3.4A) VGH  A3000 ( 4.7A) None VGH  A3000 (-3.5A) VGH  A3000 (-4.3A) None	0.87A	39.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	8 / 12	VAL A1959 ALA A1978 LYS A1980 MET A2029 GLY A2032 ASN A2084 LEU A2086 ASP A2102	None VGH  A3000 (-3.4A) VGH  A3000 ( 4.7A) None VGH  A3000 (-3.5A) None VGH  A3000 (-4.3A) None	0.80A	39.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3zfx	EPHRIN TYPE-B RECEPTOR 1 (Homo sapiens)	8 / 12	VAL A 633 ALA A 649 PHE A 699 MET A 700 GLY A 703 ASN A 749 LEU A 751 ASP A 762	None	0.59A	40.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4af3	AURORA KINASE B (Homo sapiens)	8 / 12	LEU A  83 VAL A  91 ALA A 104 LYS A 106 GLY A 160 ASN A 205 LEU A 207 ALA A 217	VX6  A 500 (-3.8A) VX6  A 500 ( 4.8A) VX6  A 500 (-3.4A) VX6  A 500 (-3.3A) VX6  A 500 (-3.3A) None VX6  A 500 (-4.6A) VX6  A 500 ( 4.2A)	1.16A	25.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4at3	BDNF/NT-3 GROWTH FACTORS RECEPTOR (Homo sapiens)	8 / 12	LEU A 560 VAL A 568 ALA A 586 LYS A 588 GLY A 639 ASN A 697 LEU A 699 ASP A 710	LTI  A1839 ( 4.2A) None LTI  A1839 (-3.3A) None LTI  A1839 (-3.4A) None LTI  A1839 (-4.2A) None	0.87A	36.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4at3	BDNF/NT-3 GROWTH FACTORS RECEPTOR (Homo sapiens)	8 / 12	LEU A 560 VAL A 568 ALA A 586 MET A 636 GLY A 639 ASN A 697 LEU A 699 ASP A 710	LTI  A1839 ( 4.2A) None LTI  A1839 (-3.3A) None LTI  A1839 (-3.4A) None LTI  A1839 (-4.2A) None	0.66A	36.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4aw5	EPHRIN TYPE-B RECEPTOR 4 (Homo sapiens)	9 / 12	VAL A 105 ALA A 121 LYS A 123 PHE A 171 MET A 172 GLY A 175 ASN A 221 LEU A 223 ASP A 234	30K  A1365 ( 4.6A) 30K  A1365 (-3.2A) 30K  A1365 (-3.8A) 30K  A1365 (-4.4A) None 30K  A1365 (-3.5A) 30K  A1365 (-4.4A) 30K  A1365 (-4.5A) 30K  A1365 (-3.3A)	0.72A	39.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4bc6	SERINE/THREONINE-PRO TEIN KINASE 10 (Homo sapiens)	9 / 12	LEU A  42 VAL A  50 ALA A  63 LYS A  65 PHE A 112 GLY A 116 ASN A 162 LEU A 164 ALA A 174	XZN  A1317 (-3.6A) XZN  A1317 ( 4.7A) XZN  A1317 (-3.5A) XZN  A1317 (-4.1A) XZN  A1317 (-4.5A) XZN  A1317 ( 3.7A) None XZN  A1317 (-4.7A) XZN  A1317 ( 4.3A)	0.98A	30.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	8 / 12	LEU A 616 VAL A 624 ALA A 653 LYS A 655 MET A 704 ASN A 771 LEU A 773 ALA A 783	None DI1  A1000 (-4.8A) DI1  A1000 (-3.6A) DI1  A1000 (-3.9A) None None DI1  A1000 (-4.5A) DI1  A1000 (-3.7A)	0.70A	37.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4crs	SERINE/THREONINE-PRO TEIN KINASE N2 (Homo sapiens)	8 / 12	LEU A 663 VAL A 671 ALA A 684 GLY A 743 ASN A 787 LEU A 789 ALA A 799 ASP A 800	AGS  A1985 (-4.2A) AGS  A1985 (-4.6A) AGS  A1985 (-3.5A) None MG  A1986 ( 3.2A) AGS  A1985 (-4.8A) AGS  A1985 ( 4.5A) AGS  A1985 ( 3.3A)	0.54A	26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4eut	SERINE/THREONINE-PRO TEIN KINASE TBK1 (Homo sapiens)	8 / 12	LEU A  15 VAL A  23 ALA A  36 LYS A  38 PHE A  88 GLY A  92 ASN A 140 ASP A 157	BX7  A 401 (-3.7A) BX7  A 401 (-4.4A) BX7  A 401 (-3.4A) BX7  A 401 ( 4.0A) BX7  A 401 ( 4.6A) BX7  A 401 (-3.5A) None BX7  A 401 ( 3.7A)	0.79A	23.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	8 / 12	LEU A1122 VAL A1130 ALA A1148 MET A1199 GLY A1202 ASN A1254 LEU A1256 ASP A1270	0UV  A1501 (-3.8A) 0UV  A1501 (-4.5A) 0UV  A1501 (-3.4A) None 0UV  A1501 (-3.6A) 0UV  A1501 ( 4.9A) 0UV  A1501 (-4.6A) 0UV  A1501 ( 4.2A)	0.79A	35.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	9 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLY A 908 ASN A 954 LEU A 956 ALA A 966 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 ( 3.8A) None 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A) 19S  A1201 ( 4.1A)	0.56A	35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4k11	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	8 / 12	LEU A 273 VAL A 281 ALA A 293 LYS A 295 MET A 341 GLY A 344 LEU A 393 ALA A 403	0J9  A 601 (-4.0A) 0J9  A 601 (-4.4A) 0J9  A 601 (-3.3A) 0J9  A 601 ( 4.7A) None 0J9  A 601 ( 4.1A) 0J9  A 601 (-4.5A) 0J9  A 601 (-3.5A)	0.92A	33.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4k11	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	8 / 12	LEU A 273 VAL A 281 ALA A 293 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403	0J9  A 601 (-4.0A) 0J9  A 601 (-4.4A) 0J9  A 601 (-3.3A) None 0J9  A 601 ( 4.1A) None 0J9  A 601 (-4.5A) 0J9  A 601 (-3.5A)	0.73A	33.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4k33	FIBROBLAST GROWTH FACTOR RECEPTOR 3 (Homo sapiens)	8 / 12	LEU A 478 VAL A 486 ALA A 506 GLY A 561 ASN A 622 LEU A 624 ALA A 634 ASP A 635	ACP  A 801 (-3.8A) ACP  A 801 (-4.2A) ACP  A 801 (-3.3A) ACP  A 801 ( 4.6A) MG  A 802 ( 2.4A) ACP  A 801 (-4.4A) None MG  A 802 ( 3.0A)	0.55A	38.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	8 / 12	LEU A  46 VAL A  54 ALA A  67 LYS A  69 GLY A 128 ASN A 178 LEU A 180 ASP A 191	SIN  A 401 ( 3.9A) None SIN  A 401 ( 3.7A) None SIN  A 401 (-3.5A) None SIN  A 401 ( 4.5A) None	0.63A	24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4oli	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	8 / 12	LEU A 903 VAL A 911 ALA A 928 LYS A 930 GLY A 984 ASN A1028 LEU A1030 ASP A1041	2TT  A1202 (-3.5A) 2TT  A1202 (-4.5A) 2TT  A1202 ( 3.9A) None 2TT  A1202 (-3.4A) 2TT  A1202 (-4.5A) 2TT  A1202 (-4.4A) 2TT  A1202 (-4.6A)	0.72A	19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4otd	SERINE/THREONINE-PRO TEIN KINASE N1 (Homo sapiens)	8 / 12	LEU A 627 VAL A 635 ALA A 648 GLY A 707 ASN A 751 LEU A 753 ALA A 763 ASP A 764	None	0.91A	26.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4rew	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (Homo sapiens)	8 / 12	LEU A  24 VAL A  32 ALA A  45 GLY A 101 ASN A 146 LEU A 148 ALA A 158 ASP A 159	STU  A 601 (-3.7A) STU  A 601 ( 4.8A) STU  A 601 (-3.2A) STU  A 601 ( 3.8A) STU  A 601 (-4.2A) STU  A 601 (-4.2A) STU  A 601 ( 3.8A) STU  A 601 (-3.7A)	0.81A	20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4usf	STE20-LIKE SERINE/THREONINE-PRO TEIN KINASE (Homo sapiens)	8 / 12	LEU A  40 VAL A  48 ALA A  61 PHE A 110 GLY A 114 ASN A 160 LEU A 162 ALA A 172	6UI  A 700 ( 4.9A) None 6UI  A 700 (-3.3A) 6UI  A 700 (-4.3A) 6UI  A 700 ( 4.2A) None 6UI  A 700 (-4.2A) 6UI  A 700 ( 4.1A)	1.02A	28.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4wsq	AP2-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	9 / 12	LEU A  52 VAL A  60 ALA A  72 LYS A  74 PHE A 128 GLY A 132 ASN A 181 LEU A 183 ASP A 194	KSA  A 405 ( 4.0A) KSA  A 405 ( 4.9A) KSA  A 405 (-3.2A) None KSA  A 405 (-4.8A) KSA  A 405 (-3.5A) KSA  A 405 (-4.0A) KSA  A 405 (-4.6A) ZN  A 403 ( 2.6A)	0.72A	23.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4xcu	FIBROBLAST GROWTH FACTOR RECEPTOR 4 (Homo sapiens)	8 / 12	LEU A 473 VAL A 481 ALA A 501 LYS A 503 GLY A 556 ASN A 617 LEU A 619 ALA A 629	40M  A1002 ( 4.6A) 40M  A1002 ( 4.5A) 40M  A1002 ( 4.1A) 40M  A1002 (-4.0A) 40M  A1002 ( 3.7A) None 40M  A1002 (-4.5A) 40M  A1002 (-3.0A)	0.83A	40.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	LEU B 267 VAL B 275 LYS B 290 PHE B 336 MET B 337 GLY B 340 LEU B 389 ALA B 399	1N1  B 601 (-3.7A) 1N1  B 601 ( 4.9A) 1N1  B 601 (-4.6A) 1N1  B 601 ( 4.2A) None 1N1  B 601 (-3.5A) 1N1  B 601 (-4.3A) 1N1  B 601 (-3.5A)	0.77A	99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	LEU B 267 VAL B 275 PHE B 336 MET B 337 GLY B 340 ASN B 387 LEU B 389 ALA B 399	1N1  B 601 (-3.7A) 1N1  B 601 ( 4.9A) 1N1  B 601 ( 4.2A) None 1N1  B 601 (-3.5A) None 1N1  B 601 (-4.3A) 1N1  B 601 (-3.5A)	0.62A	99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	VAL B 275 ALA B 288 LYS B 290 PHE B 336 MET B 337 GLY B 340 LEU B 389 ALA B 399	1N1  B 601 ( 4.9A) 1N1  B 601 (-3.5A) 1N1  B 601 (-4.6A) 1N1  B 601 ( 4.2A) None 1N1  B 601 (-3.5A) 1N1  B 601 (-4.3A) 1N1  B 601 (-3.5A)	0.76A	99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	VAL B 275 ALA B 288 PHE B 336 MET B 337 GLY B 340 ASN B 387 LEU B 389 ALA B 399	1N1  B 601 ( 4.9A) 1N1  B 601 (-3.5A) 1N1  B 601 ( 4.2A) None 1N1  B 601 (-3.5A) None 1N1  B 601 (-4.3A) 1N1  B 601 (-3.5A)	0.58A	99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	5a46	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens)	8 / 12	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLY A 567 ASN A 628 LEU A 630 ALA A 640	38O  A1769 (-3.2A) 38O  A1769 (-4.5A) 38O  A1769 (-3.6A) 38O  A1769 ( 3.1A) 38O  A1769 (-3.4A) None 38O  A1769 (-4.6A) EDO  A1766 ( 4.4A)	0.65A	40.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	5iso	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 (Homo sapiens)	9 / 12	LEU A  22 VAL A  30 ALA A  43 LYS A  45 GLY A  99 ASN A 144 LEU A 146 ALA A 156 ASP A 157	STU  A 601 (-4.1A) STU  A 601 (-4.8A) STU  A 601 (-3.3A) STU  A 601 ( 4.4A) STU  A 601 ( 4.0A) STU  A 601 (-4.3A) STU  A 601 (-4.5A) STU  A 601 (-3.5A) STU  A 601 (-3.5A)	0.87A	19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	8 / 12	VAL A  30 ALA A  43 LYS A  45 PHE A  92 GLY A  96 ASN A 141 LEU A 143 ALA A 153	6G2  A 901 ( 4.9A) 6G2  A 901 (-3.2A) 6G2  A 901 ( 3.9A) 6G2  A 901 (-4.1A) 6G2  A 901 (-3.6A) None 6G2  A 901 (-4.7A) 6G2  A 901 ( 4.2A)	0.69A	24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	8 / 12	VAL A  30 ALA A  43 PHE A  92 GLY A  96 ASN A 141 LEU A 143 ALA A 153 ASP A 154	6G2  A 901 ( 4.9A) 6G2  A 901 (-3.2A) 6G2  A 901 (-4.1A) 6G2  A 901 (-3.6A) None 6G2  A 901 (-4.7A) 6G2  A 901 ( 4.2A) 6G2  A 901 (-3.4A)	0.64A	24.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	5j9z	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	8 / 12	LEU A 718 VAL A 726 ALA A 743 LYS A 745 MET A 793 GLY A 796 ASN A 842 LEU A 844	6HJ  A1101 ( 4.6A) 6HJ  A1101 ( 4.7A) 6HJ  A1101 (-3.1A) 6HJ  A1101 (-4.2A) None 6HJ  A1101 ( 4.5A) None 6HJ  A1101 ( 4.8A)	0.86A	34.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	9 / 12	LEU A 593 VAL A 601 ALA A 617 PHE A 673 MET A 674 GLY A 677 ASN A 728 ALA A 740 ASP A 741	7AE  A1000 ( 3.9A) 7AE  A1000 ( 4.9A) 7AE  A1000 (-3.3A) 7AE  A1000 (-4.1A) None 7AE  A1000 ( 3.7A) 7AE  A1000 (-4.7A) 7AE  A1000 ( 3.7A) 7AE  A1000 (-4.4A)	0.63A	44.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	5u6b	TYROSINE-PROTEIN KINASE RECEPTOR UFO (Homo sapiens)	9 / 12	LEU A 542 VAL A 550 ALA A 565 LYS A 567 PHE A 622 MET A 623 GLY A 626 ALA A 689 ASP A 690	7YS  A9001 (-4.1A) 7YS  A9001 (-4.2A) 7YS  A9001 (-3.3A) None 7YS  A9001 (-4.3A) 7YS  A9001 (-4.7A) 7YS  A9001 (-3.4A) 7YS  A9001 (-3.4A) None	0.79A	42.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	5u6b	TYROSINE-PROTEIN KINASE RECEPTOR UFO (Homo sapiens)	9 / 12	LEU A 542 VAL A 550 ALA A 565 PHE A 622 MET A 623 GLY A 626 ASN A 677 ALA A 689 ASP A 690	7YS  A9001 (-4.1A) 7YS  A9001 (-4.2A) 7YS  A9001 (-3.3A) 7YS  A9001 (-4.3A) 7YS  A9001 (-4.7A) 7YS  A9001 (-3.4A) None 7YS  A9001 (-3.4A) None	0.76A	42.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	5u7q	RHO-ASSOCIATED PROTEIN KINASE 2 (Homo sapiens)	9 / 12	VAL A 106 ALA A 119 LYS A 121 MET A 172 GLY A 175 ASN A 219 LEU A 221 ALA A 231 ASP A 232	None	0.73A	22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	5w5j	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2 (Homo sapiens)	8 / 12	LEU A  24 VAL A  32 ALA A  45 MET A  98 GLY A 101 ASN A 151 LEU A 153 ALA A 163	9WS  A 401 ( 4.2A) 9WS  A 401 ( 4.6A) 9WS  A 401 (-3.3A) None 9WS  A 401 ( 4.3A) None 9WS  A 401 (-4.6A) 9WS  A 401 ( 4.0A)	0.63A	27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	6c7y	TYROSINE-PROTEIN KINASE JAK1 (Homo sapiens)	8 / 12	LEU A 881 VAL A 889 ALA A 906 LYS A 908 PHE A 958 GLY A 962 LEU A1010 ASP A1021	ADP  A1201 ( 4.5A) ADP  A1201 (-4.3A) ADP  A1201 (-3.4A) ADP  A1201 (-2.8A) None ADP  A1201 ( 4.1A) ADP  A1201 (-4.5A) MG  A1203 (-1.8A)	0.64A	13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	6c7y	TYROSINE-PROTEIN KINASE JAK1 (Homo sapiens)	8 / 12	LEU A 881 VAL A 889 ALA A 906 PHE A 958 GLY A 962 ASN A1008 LEU A1010 ASP A1021	ADP  A1201 ( 4.5A) ADP  A1201 (-4.3A) ADP  A1201 (-3.4A) None ADP  A1201 ( 4.1A) MG  A1202 ( 2.5A) ADP  A1201 (-4.5A) MG  A1203 (-1.8A)	0.54A	13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	VAL A 179 ALA A 192 LYS A 194 GLY A 273 ASN A 317 LEU A 319 ALA A 329 ASP A 330	F6J  A 501 (-4.6A) F6J  A 501 (-3.4A) F6J  A 501 (-2.9A) F6J  A 501 ( 3.7A) F6J  A 501 ( 4.7A) F6J  A 501 (-4.5A) F6J  A 501 ( 4.0A) F6J  A 501 (-3.8A)	0.67A	14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	6f3d	INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 (Homo sapiens)	8 / 12	VAL A 200 ALA A 211 LYS A 213 MET A 265 GLY A 268 ASN A 316 LEU A 318 ASP A 329	CJT  A 502 ( 4.8A) CJT  A 502 (-3.4A) CJT  A 502 (-3.0A) CJT  A 502 (-4.9A) CJT  A 502 ( 4.3A) None CJT  A 502 (-4.7A) CJT  A 502 ( 4.0A)	0.85A	15.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	1k2p	TYROSINE-PROTEIN KINASE BTK (Homo sapiens)	6 / 11	ALA A 428 THR A 474 MET A 477 GLY A 480 ASN A 526 LEU A 528	None	0.46A	45.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	1s9i	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 11	LEU A  78 ALA A  99 LYS A 101 MET A 150 GLY A 153 LEU A 201	ATP  A 535 (-3.9A) ATP  A 535 (-3.6A) ATP  A 535 ( 2.5A) None ATP  A 535 ( 4.7A) ATP  A 535 (-4.8A)	0.94A	24.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	1snx	TYROSINE-PROTEIN KINASE ITK/TSK (Homo sapiens)	6 / 11	ALA A 389 LYS A 391 MET A 438 GLY A 441 ASN A 487 LEU A 489	None	0.99A	40.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 11	ALA X  37 THR X  82 MET X  85 GLY X  88 ASN X 135 LEU X 137 ALA X 147	STU  X 902 (-3.1A) STU  X 902 (-4.1A) None STU  X 902 (-3.5A) STU  X 902 ( 4.9A) STU  X 902 (-4.4A) STU  X 902 ( 4.1A)	0.54A	45.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 11	LEU X  17 ALA X  37 LYS X  39 THR X  82 MET X  85 GLY X  88 LEU X 137	STU  X 902 (-3.8A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) STU  X 902 (-4.1A) None STU  X 902 (-3.5A) STU  X 902 (-4.4A)	1.21A	45.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 11	LEU X  17 ALA X  37 THR X  82 MET X  85 GLY X  88 ASN X 135 LEU X 137	STU  X 902 (-3.8A) STU  X 902 (-3.1A) STU  X 902 (-4.1A) None STU  X 902 (-3.5A) STU  X 902 ( 4.9A) STU  X 902 (-4.4A)	0.80A	45.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2h8h	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	7 / 11	ALA A 293 THR A 338 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403	H8H  A 534 (-3.2A) H8H  A 534 (-3.1A) None H8H  A 534 (-3.3A) H8H  A 534 ( 4.9A) H8H  A 534 (-4.5A) H8H  A 534 ( 4.0A)	0.57A	27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2h8h	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	7 / 11	LEU A 273 ALA A 293 LYS A 295 THR A 338 MET A 341 GLY A 344 LEU A 393	H8H  A 534 (-3.8A) H8H  A 534 (-3.2A) H8H  A 534 (-3.7A) H8H  A 534 (-3.1A) None H8H  A 534 (-3.3A) H8H  A 534 (-4.5A)	0.79A	27.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	7 / 11	ALA A 293 THR A 338 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403	QUE  A   1 (-3.5A) QUE  A   1 (-3.3A) None QUE  A   1 (-3.0A) None QUE  A   1 (-4.4A) QUE  A   1 ( 4.5A)	0.51A	33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	7 / 11	LEU A 273 ALA A 293 LYS A 295 THR A 338 MET A 341 GLY A 344 LEU A 393	QUE  A   1 (-3.9A) QUE  A   1 (-3.5A) None QUE  A   1 (-3.3A) None QUE  A   1 (-3.0A) QUE  A   1 (-4.4A)	0.71A	33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	7 / 11	LEU A 273 ALA A 293 THR A 338 MET A 341 GLY A 344 ASN A 391 LEU A 393	QUE  A   1 (-3.9A) QUE  A   1 (-3.5A) QUE  A   1 (-3.3A) None QUE  A   1 (-3.0A) None QUE  A   1 (-4.4A)	0.65A	33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	7 / 11	ALA A 271 LYS A 273 THR A 316 MET A 319 GLY A 322 ASN A 369 LEU A 371	1BM  A 499 (-3.6A) 1BM  A 499 (-3.8A) 1BM  A 499 (-3.2A) None 1BM  A 499 (-3.5A) 1BM  A 499 (-4.1A) 1BM  A 499 (-4.4A)	1.10A	46.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	8 / 11	LEU A 251 ALA A 271 THR A 316 MET A 319 GLY A 322 ASN A 369 LEU A 371 ALA A 381	1BM  A 499 ( 3.7A) 1BM  A 499 (-3.6A) 1BM  A 499 (-3.2A) None 1BM  A 499 (-3.5A) 1BM  A 499 (-4.1A) 1BM  A 499 (-4.4A) 1BM  A 499 ( 3.7A)	0.45A	46.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	7 / 11	ALA A 269 THR A 315 MET A 318 GLY A 321 ASN A 368 LEU A 370 ALA A 380	GIN  A 600 (-3.1A) GIN  A 600 (-3.4A) None None None GIN  A 600 (-4.7A) GIN  A 600 (-3.1A)	0.63A	99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	6 / 11	LEU A 248 ALA A 269 THR A 315 MET A 318 GLY A 321 LEU A 370	GIN  A 600 ( 4.6A) GIN  A 600 (-3.1A) GIN  A 600 (-3.4A) None None GIN  A 600 (-4.7A)	0.71A	99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	7 / 11	ALA A 271 THR A 316 MET A 319 GLY A 322 ASN A 369 LEU A 371 ALA A 381	1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.3A) 1N8  A 501 ( 4.4A) 1N8  A 501 ( 3.5A) None 1N8  A 501 ( 4.3A) 1N8  A 501 ( 3.3A)	0.64A	45.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	7 / 11	LEU A 251 ALA A 271 THR A 316 MET A 319 GLY A 322 LEU A 371 ALA A 381	None 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.3A) 1N8  A 501 ( 4.4A) 1N8  A 501 ( 3.5A) 1N8  A 501 ( 4.3A) 1N8  A 501 ( 3.3A)	0.86A	45.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2ogv	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR PRECURSOR (Homo sapiens)	6 / 11	LEU A 588 ALA A 614 THR A 663 GLY A 669 ASN A 783 LEU A 785	None	0.78A	37.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2qlu	ACTIVIN RECEPTOR TYPE IIB (Homo sapiens)	6 / 11	ALA A 215 THR A 265 GLY A 271 ASN A 326 LEU A 328 ALA A 338	ADE  A 488 (-3.2A) ADE  A 488 (-4.3A) ADE  A 488 ( 4.1A) None ADE  A 488 (-4.4A) None	0.58A	25.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2qob	EPHRIN RECEPTOR (Homo sapiens)	6 / 11	ALA A 651 THR A 699 MET A 702 GLY A 705 ASN A 751 LEU A 753	PTR  A 701 ( 4.7A) None PTR  A 701 ( 3.5A) None None None	0.30A	34.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2r2p	EPHRIN TYPE-A RECEPTOR 5 (Homo sapiens)	6 / 11	ALA A 705 THR A 753 MET A 756 GLY A 759 ASN A 805 LEU A 807	None	0.33A	37.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2r4b	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	6 / 11	ALA A 749 THR A 796 MET A 799 GLY A 802 ASN A 848 LEU A 850	GW7  A   1 (-3.3A) GW7  A   1 (-4.0A) None GW7  A   1 (-3.6A) None GW7  A   1 (-4.2A)	0.78A	36.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2r4b	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	7 / 11	LEU A 724 ALA A 749 LYS A 751 THR A 796 MET A 799 GLY A 802 LEU A 850	GW7  A   1 ( 4.2A) GW7  A   1 (-3.3A) GW7  A   1 (-3.9A) GW7  A   1 (-4.0A) None GW7  A   1 (-3.6A) GW7  A   1 (-4.2A)	0.94A	36.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2xk9	CHECKPOINT KINASE 2 (Homo sapiens)	6 / 11	LEU A 226 ALA A 247 LYS A 249 MET A 304 GLY A 307 LEU A 354	XK9  A1511 (-3.8A) XK9  A1511 ( 4.1A) XK9  A1511 (-4.2A) None XK9  A1511 ( 3.7A) XK9  A1511 (-4.6A)	0.80A	27.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2xk9	CHECKPOINT KINASE 2 (Homo sapiens)	6 / 11	LEU A 226 ALA A 247 MET A 304 GLY A 307 ASN A 352 LEU A 354	XK9  A1511 (-3.8A) XK9  A1511 ( 4.1A) None XK9  A1511 ( 3.7A) None XK9  A1511 (-4.6A)	0.58A	27.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2y7j	PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM (Homo sapiens)	6 / 11	ALA A  51 LYS A  53 MET A 110 GLY A 113 ASN A 158 LEU A 160	B49  A1294 (-3.2A) None None B49  A1294 (-3.6A) None B49  A1294 (-4.4A)	1.00A	26.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3b2t	FIBROBLAST GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	6 / 11	ALA A 515 LYS A 517 GLY A 570 ASN A 631 LEU A 633 ALA A 643	M33  A1996 (-3.3A) M33  A1996 ( 4.5A) M33  A1996 ( 4.8A) None M33  A1996 (-4.5A) None	0.98A	40.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3b2t	FIBROBLAST GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	6 / 11	LEU A 487 ALA A 515 LYS A 517 GLY A 570 ASN A 631 LEU A 633	M33  A1996 (-4.0A) M33  A1996 (-3.3A) M33  A1996 ( 4.5A) M33  A1996 ( 4.8A) None M33  A1996 (-4.5A)	1.02A	40.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	6 / 11	ALA A 220 THR A 266 MET A 269 GLY A 272 ASN A 319 LEU A 321	None	0.33A	44.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3dko	EPHRIN TYPE-A RECEPTOR 7 (Homo sapiens)	6 / 11	ALA A 663 LYS A 665 MET A 714 GLY A 717 ASN A 763 LEU A 765	IHZ  A1001 (-3.3A) IHZ  A1001 ( 4.5A) None IHZ  A1001 ( 3.9A) None IHZ  A1001 (-4.6A)	0.92A	36.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3kul	EPHRIN TYPE-A RECEPTOR 8 (Homo sapiens)	6 / 11	ALA A 665 THR A 713 MET A 716 GLY A 719 ASN A 765 LEU A 767	None None None GOL  A 403 (-3.4A) None None	0.38A	34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3lzb	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	6 / 11	LEU A 694 ALA A 719 THR A 766 GLY A 772 ASN A 818 LEU A 820	ITI  A   1 (-3.9A) ITI  A   1 (-2.9A) ITI  A   1 (-3.8A) ITI  A   1 (-3.5A) None ITI  A   1 (-4.6A)	0.68A	34.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3mdy	BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B (Homo sapiens)	6 / 11	ALA A 229 THR A 279 GLY A 285 ASN A 337 LEU A 339 ALA A 349	LDN  A   1 (-3.6A) LDN  A   1 (-3.8A) LDN  A   1 (-3.3A) LDN  A   1 (-4.3A) LDN  A   1 (-4.5A) LDN  A   1 ( 3.8A)	0.54A	28.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3my0	SERINE/THREONINE-PRO TEIN KINASE RECEPTOR R3 (Homo sapiens)	6 / 11	ALA A 227 THR A 277 GLY A 283 ASN A 335 LEU A 337 ALA A 347	LDN  A 600 (-3.2A) LDN  A 600 (-4.0A) LDN  A 600 (-3.3A) LDN  A 600 (-4.5A) LDN  A 600 (-4.6A) LDN  A 600 ( 3.8A)	0.48A	28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	6 / 11	LEU A 192 ALA A 213 MET A 266 GLY A 269 ASN A 316 LEU A 318	AMP  A 577 ( 4.3A) AMP  A 577 (-3.4A) None None AMP  A 577 (-4.2A) AMP  A 577 (-4.8A)	0.65A	19.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	6 / 11	ALA A 751 THR A 798 MET A 801 GLY A 804 ASN A 850 LEU A 852	03Q  A   1 (-3.1A) 03Q  A   1 (-4.1A) None 03Q  A   1 ( 3.9A) 03Q  A   1 (-4.2A) 03Q  A   1 (-4.4A)	0.62A	35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	7 / 11	LEU A 726 ALA A 751 LYS A 753 THR A 798 MET A 801 GLY A 804 LEU A 852	03Q  A   1 (-3.8A) 03Q  A   1 (-3.1A) 03Q  A   1 (-4.7A) 03Q  A   1 (-4.1A) None 03Q  A   1 ( 3.9A) 03Q  A   1 (-4.4A)	1.02A	35.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3q4t	ACTIVIN RECEPTOR TYPE-2A (Homo sapiens)	6 / 11	ALA A 217 THR A 267 GLY A 273 ASN A 327 LEU A 329 ALA A 339	TAK  A   2 (-3.5A) TAK  A   2 (-3.5A) TAK  A   2 (-3.6A) None TAK  A   2 (-4.6A) TAK  A   2 ( 4.2A)	0.57A	25.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3sxs	CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX (Homo sapiens)	6 / 11	LEU A 423 ALA A 443 LYS A 445 THR A 489 GLY A 495 ASN A 541	PP2  A   1 (-4.1A) PP2  A   1 (-3.2A) PP2  A   1 (-4.5A) PP2  A   1 (-3.3A) PP2  A   1 ( 4.2A) None	0.84A	41.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3sxs	CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX (Homo sapiens)	6 / 11	LEU A 423 ALA A 443 THR A 489 GLY A 495 ASN A 541 LEU A 543	PP2  A   1 (-4.1A) PP2  A   1 (-3.2A) PP2  A   1 (-3.3A) PP2  A   1 ( 4.2A) None PP2  A   1 (-4.6A)	0.54A	41.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3v5q	NT-3 GROWTH FACTOR RECEPTOR (Homo sapiens)	7 / 11	LEU A 544 ALA A 570 LYS A 572 MET A 620 GLY A 623 ASN A 684 LEU A 686	0F4  A 902 ( 4.2A) 0F4  A 902 (-3.2A) 0F4  A 902 (-4.0A) None 0F4  A 902 (-3.4A) None 0F4  A 902 (-4.5A)	0.67A	36.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3w18	AURORA KINASE A (Homo sapiens)	6 / 11	ALA A 160 LYS A 146 GLY A 216 ASN A 261 LEU A 263 ALA A 273	N13  A 501 ( 4.1A) None N13  A 501 (-3.5A) None N13  A 501 (-4.5A) N13  A 501 ( 3.8A)	0.78A	27.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3w18	AURORA KINASE A (Homo sapiens)	6 / 11	ALA A 160 LYS A 162 GLY A 216 ASN A 261 LEU A 263 ALA A 273	N13  A 501 ( 4.1A) N13  A 501 (-2.9A) N13  A 501 (-3.5A) None N13  A 501 (-4.5A) N13  A 501 ( 3.8A)	1.01A	27.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3wig	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 (Homo sapiens)	6 / 11	LEU A  75 ALA A  96 MET A 147 GLY A 150 ASN A 196 LEU A 198	ANP  A 401 (-3.8A) ANP  A 401 (-3.2A) None ANP  A 401 ( 4.3A) MG  A 402 ( 2.9A) ANP  A 401 (-4.8A)	0.81A	24.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	6 / 11	LEU A1951 ALA A1978 MET A2029 GLY A2032 ASN A2084 LEU A2086	VGH  A3000 ( 4.4A) VGH  A3000 (-3.4A) None VGH  A3000 (-3.5A) None VGH  A3000 (-4.3A)	0.46A	40.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3zfx	EPHRIN TYPE-B RECEPTOR 1 (Homo sapiens)	6 / 11	ALA A 649 THR A 697 MET A 700 GLY A 703 ASN A 749 LEU A 751	None	0.21A	41.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4af3	AURORA KINASE B (Homo sapiens)	6 / 11	ALA A 104 LYS A 106 GLY A 160 ASN A 205 LEU A 207 ALA A 217	VX6  A 500 (-3.4A) VX6  A 500 (-3.3A) VX6  A 500 (-3.3A) None VX6  A 500 (-4.6A) VX6  A 500 ( 4.2A)	0.96A	25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4af3	AURORA KINASE B (Homo sapiens)	6 / 11	LEU A  83 ALA A 104 LYS A 106 GLY A 160 ASN A 205 LEU A 207	VX6  A 500 (-3.8A) VX6  A 500 (-3.4A) VX6  A 500 (-3.3A) VX6  A 500 (-3.3A) None VX6  A 500 (-4.6A)	0.88A	25.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4at3	BDNF/NT-3 GROWTH FACTORS RECEPTOR (Homo sapiens)	6 / 11	LEU A 560 ALA A 586 MET A 636 GLY A 639 ASN A 697 LEU A 699	LTI  A1839 ( 4.2A) LTI  A1839 (-3.3A) None LTI  A1839 (-3.4A) None LTI  A1839 (-4.2A)	0.64A	36.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4aw5	EPHRIN TYPE-B RECEPTOR 4 (Homo sapiens)	6 / 11	ALA A 121 THR A 169 MET A 172 GLY A 175 ASN A 221 LEU A 223	30K  A1365 (-3.2A) 30K  A1365 (-3.8A) None 30K  A1365 (-3.5A) 30K  A1365 (-4.4A) 30K  A1365 (-4.5A)	0.32A	38.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4c02	ACTIVIN RECEPTOR TYPE-1 (Homo sapiens)	6 / 11	ALA A 233 THR A 283 GLY A 289 ASN A 341 LEU A 343 ALA A 353	TAK  A1507 (-3.3A) TAK  A1507 (-3.6A) TAK  A1507 (-3.5A) None TAK  A1507 (-4.7A) TAK  A1507 ( 4.2A)	0.39A	27.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	7 / 11	ALA A 653 THR A 701 MET A 704 GLY A 707 ASN A 771 LEU A 773 ALA A 783	DI1  A1000 (-3.6A) DI1  A1000 (-3.6A) None None None DI1  A1000 (-4.5A) DI1  A1000 (-3.7A)	0.67A	37.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	8 / 11	LEU A 616 ALA A 653 LYS A 655 THR A 701 MET A 704 ASN A 771 LEU A 773 ALA A 783	None DI1  A1000 (-3.6A) DI1  A1000 (-3.9A) DI1  A1000 (-3.6A) None None DI1  A1000 (-4.5A) DI1  A1000 (-3.7A)	1.32A	37.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4f0i	HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR (Homo sapiens)	6 / 11	LEU A 515 ALA A 541 MET A 591 GLY A 594 ASN A 654 LEU A 656	None	0.44A	36.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	6 / 11	LEU A1122 ALA A1148 MET A1199 GLY A1202 ASN A1254 LEU A1256	0UV  A1501 (-3.8A) 0UV  A1501 (-3.4A) None 0UV  A1501 (-3.6A) 0UV  A1501 ( 4.9A) 0UV  A1501 (-4.6A)	0.51A	37.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4id7	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	6 / 11	LEU A 132 ALA A 156 THR A 205 GLY A 211 ASN A 257 LEU A 259	1G0  A 401 ( 4.5A) 1G0  A 401 (-3.6A) 1G0  A 401 (-3.2A) 1G0  A 401 ( 4.5A) None 1G0  A 401 (-4.6A)	0.74A	40.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4k11	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	6 / 11	LEU A 273 ALA A 293 LYS A 295 MET A 341 GLY A 344 LEU A 393	0J9  A 601 (-4.0A) 0J9  A 601 (-3.3A) 0J9  A 601 ( 4.7A) None 0J9  A 601 ( 4.1A) 0J9  A 601 (-4.5A)	1.01A	35.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4k11	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	7 / 11	LEU A 273 ALA A 293 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403	0J9  A 601 (-4.0A) 0J9  A 601 (-3.3A) None 0J9  A 601 ( 4.1A) None 0J9  A 601 (-4.5A) 0J9  A 601 (-3.5A)	0.64A	35.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4lg4	SERINE/THREONINE-PRO TEIN KINASE 3 (Homo sapiens)	6 / 11	LEU A  33 ALA A  54 GLY A 105 ASN A 151 LEU A 153 ALA A 163	GOL  A 404 ( 3.6A) GOL  A 404 ( 3.1A) GOL  A 404 (-3.6A) None GOL  A 403 ( 4.4A) GOL  A 403 ( 3.0A)	0.79A	24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	7 / 11	LEU A  46 ALA A  67 LYS A  69 THR A 123 GLY A 128 ASN A 178 LEU A 180	SIN  A 401 ( 3.9A) SIN  A 401 ( 3.7A) None None SIN  A 401 (-3.5A) None SIN  A 401 ( 4.5A)	1.36A	25.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4p2k	EPHRIN TYPE-A RECEPTOR 2 (Homo sapiens)	6 / 11	ALA A 644 THR A 692 MET A 695 GLY A 698 ASN A 744 LEU A 746	None	0.42A	38.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4usf	STE20-LIKE SERINE/THREONINE-PRO TEIN KINASE (Homo sapiens)	7 / 11	LEU A  40 ALA A  61 GLY A 114 ASN A 160 LEU A 162 ALA A 172 PHE A 174	6UI  A 700 ( 4.9A) 6UI  A 700 (-3.3A) 6UI  A 700 ( 4.2A) None 6UI  A 700 (-4.2A) 6UI  A 700 ( 4.1A) None	1.01A	29.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	7 / 11	LEU B 267 ALA B 288 LYS B 290 THR B 334 MET B 337 GLY B 340 LEU B 389	1N1  B 601 (-3.7A) 1N1  B 601 (-3.5A) 1N1  B 601 (-4.6A) 1N1  B 601 (-3.3A) None 1N1  B 601 (-3.5A) 1N1  B 601 (-4.3A)	0.72A	78.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 11	LEU B 267 ALA B 288 THR B 334 MET B 337 GLY B 340 ASN B 387 LEU B 389 ALA B 399	1N1  B 601 (-3.7A) 1N1  B 601 (-3.5A) 1N1  B 601 (-3.3A) None 1N1  B 601 (-3.5A) None 1N1  B 601 (-4.3A) 1N1  B 601 (-3.5A)	0.46A	78.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 11	LEU B 267 ALA B 288 THR B 334 MET B 337 GLY B 340 LEU B 389 ALA B 399 PHE B 401	1N1  B 601 (-3.7A) 1N1  B 601 (-3.5A) 1N1  B 601 (-3.3A) None 1N1  B 601 (-3.5A) 1N1  B 601 (-4.3A) 1N1  B 601 (-3.5A) None	0.76A	78.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5hor	HEPATOCYTE GROWTH FACTOR RECEPTOR (Homo sapiens)	6 / 11	ALA A1108 LYS A1110 MET A1160 GLY A1163 ASN A1209 ALA A1221	63K  A1401 (-3.5A) None None 63K  A1401 (-3.6A) None 63K  A1401 (-3.3A)	0.84A	37.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5hx6	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 1 (Homo sapiens)	6 / 11	LYS A  45 MET A  95 GLY A  98 ASN A 143 LEU A 145 ALA A 155	65U  A 301 (-3.4A) None None None None 65U  A 301 ( 3.9A)	0.72A	29.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5j9z	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	7 / 11	LEU A 718 ALA A 743 LYS A 745 MET A 793 GLY A 796 ASN A 842 LEU A 844	6HJ  A1101 ( 4.6A) 6HJ  A1101 (-3.1A) 6HJ  A1101 (-4.2A) None 6HJ  A1101 ( 4.5A) None 6HJ  A1101 ( 4.8A)	1.03A	35.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5ko1	MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN (Homo sapiens)	6 / 11	LEU A 209 ALA A 228 GLY A 289 ASN A 336 LEU A 338 ALA A 348	None 6UY  A 501 (-3.4A) 6UY  A 501 ( 4.3A) 6UY  A 501 (-4.4A) 6UY  A 501 (-4.5A) 6UY  A 501 (-3.4A)	0.62A	29.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5l6o	EPHRIN TYPE-B RECEPTOR 3 (Homo sapiens)	7 / 11	ALA A 663 LYS A 665 THR A 711 MET A 714 ASN A 763 LEU A 765 PHE A 777	6P6  A1001 (-3.3A) None 6P6  A1001 (-3.5A) None None 6P6  A1001 (-4.5A) DIO  A1002 (-4.5A)	1.29A	38.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	6 / 11	LEU A 593 ALA A 617 MET A 674 GLY A 677 ASN A 728 ALA A 740	7AE  A1000 ( 3.9A) 7AE  A1000 (-3.3A) None 7AE  A1000 ( 3.7A) 7AE  A1000 (-4.7A) 7AE  A1000 ( 3.7A)	0.71A	42.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5u6b	TYROSINE-PROTEIN KINASE RECEPTOR UFO (Homo sapiens)	6 / 11	LEU A 542 ALA A 565 MET A 623 GLY A 626 ASN A 677 ALA A 689	7YS  A9001 (-4.1A) 7YS  A9001 (-3.3A) 7YS  A9001 (-4.7A) 7YS  A9001 (-3.4A) None 7YS  A9001 (-3.4A)	0.71A	43.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5w5j	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2 (Homo sapiens)	7 / 11	ALA A  45 THR A  95 MET A  98 GLY A 101 ASN A 151 LEU A 153 ALA A 163	9WS  A 401 (-3.3A) 9WS  A 401 (-3.2A) None 9WS  A 401 ( 4.3A) None 9WS  A 401 (-4.6A) 9WS  A 401 ( 4.0A)	0.60A	27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5w5j	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2 (Homo sapiens)	7 / 11	LEU A  24 ALA A  45 THR A  95 MET A  98 GLY A 101 ASN A 151 LEU A 153	9WS  A 401 ( 4.2A) 9WS  A 401 (-3.3A) 9WS  A 401 (-3.2A) None 9WS  A 401 ( 4.3A) None 9WS  A 401 (-4.6A)	0.74A	27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	6cz4	PROTEIN-TYROSINE KINASE 6 (Homo sapiens)	8 / 11	LEU A 197 ALA A 217 LYS A 219 THR A 264 MET A 267 GLY A 270 ASN A 317 LEU A 319	FKY  A9001 (-4.1A) FKY  A9001 (-3.3A) None FKY  A9001 (-3.0A) None FKY  A9001 (-3.3A) None FKY  A9001 ( 4.9A)	0.78A	18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_A_AXIA9000_1 (TYROSINE-PROTEIN KINASE ABL1)	6f3d	INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 (Homo sapiens)	6 / 11	ALA A 211 LYS A 213 MET A 265 GLY A 268 ASN A 316 LEU A 318	CJT  A 502 (-3.4A) CJT  A 502 (-3.0A) CJT  A 502 (-4.9A) CJT  A 502 ( 4.3A) None CJT  A 502 (-4.7A)	0.95A	11.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	1k2p	TYROSINE-PROTEIN KINASE BTK (Homo sapiens)	7 / 12	VAL A 416 ALA A 428 LYS A 430 THR A 474 MET A 477 GLY A 480 LEU A 528	None	0.79A	45.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	1k2p	TYROSINE-PROTEIN KINASE BTK (Homo sapiens)	7 / 12	VAL A 416 ALA A 428 THR A 474 MET A 477 GLY A 480 ASN A 526 LEU A 528	None	0.81A	45.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2ac5	MAP KINASE-INTERACTING SERINE/THREONINE KINASE 2 (Homo sapiens)	7 / 12	VAL A  98 ALA A 111 LYS A 113 MET A 162 GLY A 165 ASN A 210 LEU A 212	None	0.75A	24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2buj	SERINE/THREONINE-PRO TEIN KINASE 16 (Homo sapiens)	7 / 12	VAL A  34 ALA A  47 LYS A  49 PHE A 100 GLY A 104 ASN A 153 LEU A 155	STU  A1301 (-4.8A) STU  A1301 (-3.6A) STU  A1301 ( 4.0A) STU  A1301 (-4.5A) STU  A1301 ( 4.0A) None STU  A1301 ( 4.8A)	0.71A	23.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	8 / 12	VAL X  25 ALA X  37 LYS X  39 THR X  82 MET X  85 GLY X  88 LEU X 137 ALA X 147	STU  X 902 ( 4.8A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) STU  X 902 (-4.1A) None STU  X 902 (-3.5A) STU  X 902 (-4.4A) STU  X 902 ( 4.1A)	0.71A	45.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	8 / 12	VAL X  25 ALA X  37 THR X  82 MET X  85 GLY X  88 ASN X 135 LEU X 137 ALA X 147	STU  X 902 ( 4.8A) STU  X 902 (-3.1A) STU  X 902 (-4.1A) None STU  X 902 (-3.5A) STU  X 902 ( 4.9A) STU  X 902 (-4.4A) STU  X 902 ( 4.1A)	0.50A	45.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2h8h	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	8 / 12	VAL A 281 ALA A 293 THR A 338 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403	H8H  A 534 (-4.4A) H8H  A 534 (-3.2A) H8H  A 534 (-3.1A) None H8H  A 534 (-3.3A) H8H  A 534 ( 4.9A) H8H  A 534 (-4.5A) H8H  A 534 ( 4.0A)	0.80A	27.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	8 / 12	ALA A 293 THR A 338 PHE A 340 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403	QUE  A   1 (-3.5A) QUE  A   1 (-3.3A) QUE  A   1 (-4.2A) None QUE  A   1 (-3.0A) None QUE  A   1 (-4.4A) QUE  A   1 ( 4.5A)	0.58A	33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	8 / 12	VAL A 281 ALA A 293 LYS A 295 THR A 338 PHE A 340 MET A 341 LEU A 393 ALA A 403	QUE  A   1 ( 4.8A) QUE  A   1 (-3.5A) None QUE  A   1 (-3.3A) QUE  A   1 (-4.2A) None QUE  A   1 (-4.4A) QUE  A   1 ( 4.5A)	1.17A	33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	8 / 12	VAL A 281 ALA A 293 THR A 338 PHE A 340 MET A 341 ASN A 391 LEU A 393 ALA A 403	QUE  A   1 ( 4.8A) QUE  A   1 (-3.5A) QUE  A   1 (-3.3A) QUE  A   1 (-4.2A) None None QUE  A   1 (-4.4A) QUE  A   1 ( 4.5A)	0.85A	33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	9 / 12	VAL A 259 ALA A 271 LYS A 273 THR A 316 PHE A 318 MET A 319 GLY A 322 LEU A 371 ALA A 381	1BM  A 499 ( 4.8A) 1BM  A 499 (-3.6A) 1BM  A 499 (-3.8A) 1BM  A 499 (-3.2A) 1BM  A 499 (-4.1A) None 1BM  A 499 (-3.5A) 1BM  A 499 (-4.4A) 1BM  A 499 ( 3.7A)	0.79A	46.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	9 / 12	VAL A 259 ALA A 271 THR A 316 PHE A 318 MET A 319 GLY A 322 ASN A 369 LEU A 371 ALA A 381	1BM  A 499 ( 4.8A) 1BM  A 499 (-3.6A) 1BM  A 499 (-3.2A) 1BM  A 499 (-4.1A) None 1BM  A 499 (-3.5A) 1BM  A 499 (-4.1A) 1BM  A 499 (-4.4A) 1BM  A 499 ( 3.7A)	0.69A	46.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	9 / 12	VAL A 256 ALA A 269 LYS A 271 THR A 315 PHE A 317 MET A 318 GLY A 321 LEU A 370 ALA A 380	GIN  A 600 ( 4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-3.6A) GIN  A 600 (-3.4A) GIN  A 600 (-4.3A) None None GIN  A 600 (-4.7A) GIN  A 600 (-3.1A)	0.63A	99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	9 / 12	VAL A 256 ALA A 269 THR A 315 PHE A 317 MET A 318 GLY A 321 ASN A 368 LEU A 370 ALA A 380	GIN  A 600 ( 4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-3.4A) GIN  A 600 (-4.3A) None None None GIN  A 600 (-4.7A) GIN  A 600 (-3.1A)	0.64A	99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	8 / 12	VAL A 259 ALA A 271 LYS A 273 THR A 316 MET A 319 GLY A 322 LEU A 371 ALA A 381	None 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.3A) 1N8  A 501 ( 4.4A) 1N8  A 501 ( 3.5A) 1N8  A 501 ( 4.3A) 1N8  A 501 ( 3.3A)	0.78A	45.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	8 / 12	VAL A 259 ALA A 271 THR A 316 MET A 319 GLY A 322 ASN A 369 LEU A 371 ALA A 381	None 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.3A) 1N8  A 501 ( 4.4A) 1N8  A 501 ( 3.5A) None 1N8  A 501 ( 4.3A) 1N8  A 501 ( 3.3A)	0.70A	45.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2qlu	ACTIVIN RECEPTOR TYPE IIB (Homo sapiens)	7 / 12	VAL A 204 ALA A 215 LYS A 217 THR A 265 PHE A 267 LEU A 328 ALA A 338	ADE  A 488 ( 4.9A) ADE  A 488 (-3.2A) None ADE  A 488 (-4.3A) ADE  A 488 (-4.3A) ADE  A 488 (-4.4A) None	0.96A	25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2qlu	ACTIVIN RECEPTOR TYPE IIB (Homo sapiens)	8 / 12	VAL A 204 ALA A 215 THR A 265 PHE A 267 GLY A 271 ASN A 326 LEU A 328 ALA A 338	ADE  A 488 ( 4.9A) ADE  A 488 (-3.2A) ADE  A 488 (-4.3A) ADE  A 488 (-4.3A) ADE  A 488 ( 4.1A) None ADE  A 488 (-4.4A) None	0.74A	25.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2qob	EPHRIN RECEPTOR (Homo sapiens)	7 / 12	VAL A 635 ALA A 651 THR A 699 MET A 702 GLY A 705 ASN A 751 LEU A 753	BME  A   1 (-4.9A) PTR  A 701 ( 4.7A) None PTR  A 701 ( 3.5A) None None None	0.77A	34.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2r2p	EPHRIN TYPE-A RECEPTOR 5 (Homo sapiens)	7 / 12	VAL A 689 ALA A 705 THR A 753 MET A 756 GLY A 759 ASN A 805 LEU A 807	None	0.58A	37.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2xik	SERINE/THREONINE PROTEIN KINASE 25 (Homo sapiens)	7 / 12	VAL A  34 ALA A  47 LYS A  49 GLY A 101 ASN A 145 LEU A 147 ALA A 157	J60  A1294 ( 4.9A) J60  A1294 (-3.3A) None J60  A1294 ( 3.8A) None J60  A1294 (-4.8A) J60  A1294 ( 4.2A)	0.98A	27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	2y7j	PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM (Homo sapiens)	7 / 12	VAL A  38 ALA A  51 LYS A  53 MET A 110 GLY A 113 ASN A 158 LEU A 160	None B49  A1294 (-3.2A) None None B49  A1294 (-3.6A) None B49  A1294 (-4.4A)	0.90A	26.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3b2t	FIBROBLAST GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	VAL A 495 ALA A 515 LYS A 517 GLY A 570 ASN A 631 LEU A 633 ALA A 643	M33  A1996 ( 4.7A) M33  A1996 (-3.3A) M33  A1996 ( 4.5A) M33  A1996 ( 4.8A) None M33  A1996 (-4.5A) None	0.86A	40.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3c0i	PERIPHERAL PLASMA MEMBRANE PROTEIN CASK (Homo sapiens)	7 / 12	VAL A  26 ALA A  39 LYS A  41 PHE A  93 MET A  94 GLY A  96 LEU A 148	3AM  A 338 ( 4.1A) 3AM  A 338 (-3.3A) 3AM  A 338 (-2.9A) 3AM  A 338 ( 4.6A) None None 3AM  A 338 (-4.7A)	0.89A	25.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	7 / 12	VAL A 209 ALA A 220 LYS A 222 THR A 266 MET A 269 GLY A 272 LEU A 321	None	0.72A	44.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	7 / 12	VAL A 209 ALA A 220 THR A 266 MET A 269 GLY A 272 ASN A 319 LEU A 321	None	0.60A	44.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3dko	EPHRIN TYPE-A RECEPTOR 7 (Homo sapiens)	8 / 12	VAL A 647 ALA A 663 LYS A 665 PHE A 713 MET A 714 GLY A 717 ASN A 763 LEU A 765	IHZ  A1001 ( 4.4A) IHZ  A1001 (-3.3A) IHZ  A1001 ( 4.5A) None None IHZ  A1001 ( 3.9A) None IHZ  A1001 (-4.6A)	0.92A	36.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3dtc	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9 (Homo sapiens)	7 / 12	VAL A 158 ALA A 169 LYS A 171 PHE A 222 GLY A 226 ASN A 273 LEU A 275	VIN  A6331 (-4.7A) VIN  A6331 (-3.4A) None VIN  A6331 ( 4.8A) VIN  A6331 (-3.4A) VIN  A6331 ( 4.8A) VIN  A6331 (-4.5A)	0.72A	34.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3iec	SERINE/THREONINE-PRO TEIN KINASE MARK2 (Homo sapiens)	7 / 12	VAL A  67 ALA A  80 LYS A  82 GLY A 135 ASN A 180 LEU A 182 ALA A 192	None	0.88A	25.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3kul	EPHRIN TYPE-A RECEPTOR 8 (Homo sapiens)	7 / 12	VAL A 649 ALA A 665 LYS A 667 THR A 713 MET A 716 GLY A 719 LEU A 767	None None None None None GOL  A 403 (-3.4A) None	0.69A	34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3kul	EPHRIN TYPE-A RECEPTOR 8 (Homo sapiens)	7 / 12	VAL A 649 ALA A 665 THR A 713 MET A 716 GLY A 719 ASN A 765 LEU A 767	None None None None GOL  A 403 (-3.4A) None None	0.63A	34.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3mdy	BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B (Homo sapiens)	7 / 12	VAL A 218 ALA A 229 LYS A 231 THR A 279 GLY A 285 LEU A 339 ALA A 349	LDN  A   1 ( 4.8A) LDN  A   1 (-3.6A) None LDN  A   1 (-3.8A) LDN  A   1 (-3.3A) LDN  A   1 (-4.5A) LDN  A   1 ( 3.8A)	0.83A	28.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3my0	SERINE/THREONINE-PRO TEIN KINASE RECEPTOR R3 (Homo sapiens)	7 / 12	VAL A 216 ALA A 227 THR A 277 GLY A 283 ASN A 335 LEU A 337 ALA A 347	LDN  A 600 (-4.5A) LDN  A 600 (-3.2A) LDN  A 600 (-4.0A) LDN  A 600 (-3.3A) LDN  A 600 (-4.5A) LDN  A 600 (-4.6A) LDN  A 600 ( 3.8A)	0.80A	28.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	7 / 12	VAL A 734 ALA A 751 THR A 798 MET A 801 GLY A 804 ASN A 850 LEU A 852	03Q  A   1 (-4.5A) 03Q  A   1 (-3.1A) 03Q  A   1 (-4.1A) None 03Q  A   1 ( 3.9A) 03Q  A   1 (-4.2A) 03Q  A   1 (-4.4A)	0.76A	35.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3q4t	ACTIVIN RECEPTOR TYPE-2A (Homo sapiens)	7 / 12	ALA A 217 THR A 267 PHE A 269 GLY A 273 ASN A 327 LEU A 329 ALA A 339	TAK  A   2 (-3.5A) TAK  A   2 (-3.5A) TAK  A   2 (-4.3A) TAK  A   2 (-3.6A) None TAK  A   2 (-4.6A) TAK  A   2 ( 4.2A)	0.65A	25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3q4t	ACTIVIN RECEPTOR TYPE-2A (Homo sapiens)	7 / 12	VAL A 206 ALA A 217 THR A 267 GLY A 273 ASN A 327 LEU A 329 ALA A 339	TAK  A   2 ( 4.9A) TAK  A   2 (-3.5A) TAK  A   2 (-3.5A) TAK  A   2 (-3.6A) None TAK  A   2 (-4.6A) TAK  A   2 ( 4.2A)	0.70A	25.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3tt0	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	7 / 12	VAL A 492 ALA A 512 LYS A 514 GLY A 567 ASN A 628 LEU A 630 ALA A 640	07J  A   1 (-4.0A) 07J  A   1 (-3.5A) 07J  A   1 (-4.5A) 07J  A   1 (-3.7A) None 07J  A   1 ( 4.4A) 07J  A   1 (-3.2A)	0.85A	38.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	7 / 12	VAL A 369 ALA A 382 LYS A 384 PHE A 435 GLY A 439 LEU A 486 ALA A 496	07U  A   1 (-4.8A) 07U  A   1 (-3.3A) 07U  A   1 (-3.0A) None None 07U  A   1 (-4.3A) 07U  A   1 ( 4.0A)	0.77A	25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	7 / 12	VAL A 369 ALA A 382 PHE A 435 GLY A 439 ASN A 484 LEU A 486 ALA A 496	07U  A   1 (-4.8A) 07U  A   1 (-3.3A) None None None 07U  A   1 (-4.3A) 07U  A   1 ( 4.0A)	0.78A	25.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3vid	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	VAL A 848 ALA A 866 LYS A 868 PHE A 918 GLY A 922 ASN A1033 LEU A1035	4TT  A2001 ( 4.5A) 4TT  A2001 (-3.5A) None 4TT  A2001 (-4.5A) 4TT  A2001 (-3.7A) None 4TT  A2001 (-4.8A)	0.75A	34.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	VAL A 848 ALA A 866 LYS A 868 PHE A 918 GLY A 922 ASN A1033 LEU A1035	LEV  A1201 ( 4.9A) LEV  A1201 (-3.5A) None LEV  A1201 (-4.7A) LEV  A1201 (-3.6A) GOL  A1210 (-3.6A) LEV  A1201 (-4.8A)	0.87A	37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	7 / 12	VAL A1959 ALA A1978 LYS A1980 MET A2029 GLY A2032 ASN A2084 LEU A2086	None VGH  A3000 (-3.4A) VGH  A3000 ( 4.7A) None VGH  A3000 (-3.5A) None VGH  A3000 (-4.3A)	0.99A	40.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	3zfx	EPHRIN TYPE-B RECEPTOR 1 (Homo sapiens)	8 / 12	VAL A 633 ALA A 649 THR A 697 PHE A 699 MET A 700 GLY A 703 ASN A 749 LEU A 751	None	0.64A	41.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4aw5	EPHRIN TYPE-B RECEPTOR 4 (Homo sapiens)	7 / 12	VAL A 105 ALA A 121 LYS A 123 THR A 169 PHE A 171 MET A 172 ASN A 221	30K  A1365 ( 4.6A) 30K  A1365 (-3.2A) 30K  A1365 (-3.8A) 30K  A1365 (-3.8A) 30K  A1365 (-4.4A) None 30K  A1365 (-4.4A)	0.93A	38.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4aw5	EPHRIN TYPE-B RECEPTOR 4 (Homo sapiens)	8 / 12	VAL A 105 ALA A 121 THR A 169 PHE A 171 MET A 172 GLY A 175 ASN A 221 LEU A 223	30K  A1365 ( 4.6A) 30K  A1365 (-3.2A) 30K  A1365 (-3.8A) 30K  A1365 (-4.4A) None 30K  A1365 (-3.5A) 30K  A1365 (-4.4A) 30K  A1365 (-4.5A)	0.67A	38.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4bc6	SERINE/THREONINE-PRO TEIN KINASE 10 (Homo sapiens)	8 / 12	VAL A  50 ALA A  63 LYS A  65 PHE A 112 GLY A 116 ASN A 162 LEU A 164 ALA A 174	XZN  A1317 ( 4.7A) XZN  A1317 (-3.5A) XZN  A1317 (-4.1A) XZN  A1317 (-4.5A) XZN  A1317 ( 3.7A) None XZN  A1317 (-4.7A) XZN  A1317 ( 4.3A)	1.13A	29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4c02	ACTIVIN RECEPTOR TYPE-1 (Homo sapiens)	7 / 12	VAL A 222 ALA A 233 THR A 283 GLY A 289 ASN A 341 LEU A 343 ALA A 353	TAK  A1507 (-4.7A) TAK  A1507 (-3.3A) TAK  A1507 (-3.6A) TAK  A1507 (-3.5A) None TAK  A1507 (-4.7A) TAK  A1507 ( 4.2A)	0.74A	27.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	9 / 12	VAL A 624 ALA A 653 LYS A 655 THR A 701 MET A 704 GLY A 707 ASN A 771 LEU A 773 ALA A 783	DI1  A1000 (-4.8A) DI1  A1000 (-3.6A) DI1  A1000 (-3.9A) DI1  A1000 (-3.6A) None None None DI1  A1000 (-4.5A) DI1  A1000 (-3.7A)	0.71A	37.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4f0i	HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR (Homo sapiens)	7 / 12	VAL A 523 ALA A 541 LYS A 543 MET A 591 GLY A 594 ASN A 654 LEU A 656	None	0.70A	36.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4k11	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	7 / 12	VAL A 281 ALA A 293 MET A 341 GLY A 344 ASN A 391 LEU A 393 ALA A 403	0J9  A 601 (-4.4A) 0J9  A 601 (-3.3A) None 0J9  A 601 ( 4.1A) None 0J9  A 601 (-4.5A) 0J9  A 601 (-3.5A)	0.79A	35.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	7 / 12	VAL A  54 ALA A  67 LYS A  69 THR A 123 GLY A 128 ASN A 178 LEU A 180	None SIN  A 401 ( 3.7A) None None SIN  A 401 (-3.5A) None SIN  A 401 ( 4.5A)	0.71A	25.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4p2k	EPHRIN TYPE-A RECEPTOR 2 (Homo sapiens)	7 / 12	VAL A 627 ALA A 644 THR A 692 MET A 695 GLY A 698 ASN A 744 LEU A 746	None	0.85A	38.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4usf	STE20-LIKE SERINE/THREONINE-PRO TEIN KINASE (Homo sapiens)	7 / 12	ALA A  61 PHE A 110 GLY A 114 ASN A 160 LEU A 162 ALA A 172 PHE A 174	6UI  A 700 (-3.3A) 6UI  A 700 (-4.3A) 6UI  A 700 ( 4.2A) None 6UI  A 700 (-4.2A) 6UI  A 700 ( 4.1A) None	1.31A	29.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4usf	STE20-LIKE SERINE/THREONINE-PRO TEIN KINASE (Homo sapiens)	7 / 12	VAL A  48 ALA A  61 PHE A 110 GLY A 114 ASN A 160 LEU A 162 ALA A 172	None 6UI  A 700 (-3.3A) 6UI  A 700 (-4.3A) 6UI  A 700 ( 4.2A) None 6UI  A 700 (-4.2A) 6UI  A 700 ( 4.1A)	1.04A	29.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4wsq	AP2-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	7 / 12	VAL A  60 ALA A  72 LYS A  74 PHE A 128 GLY A 132 ASN A 181 LEU A 183	KSA  A 405 ( 4.9A) KSA  A 405 (-3.2A) None KSA  A 405 (-4.8A) KSA  A 405 (-3.5A) KSA  A 405 (-4.0A) KSA  A 405 (-4.6A)	0.78A	24.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4xcu	FIBROBLAST GROWTH FACTOR RECEPTOR 4 (Homo sapiens)	7 / 12	VAL A 481 ALA A 501 LYS A 503 GLY A 556 ASN A 617 LEU A 619 ALA A 629	40M  A1002 ( 4.5A) 40M  A1002 ( 4.1A) 40M  A1002 (-4.0A) 40M  A1002 ( 3.7A) None 40M  A1002 (-4.5A) 40M  A1002 (-3.0A)	0.93A	40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	9 / 12	VAL B 275 ALA B 288 THR B 334 PHE B 336 MET B 337 GLY B 340 ASN B 387 LEU B 389 ALA B 399	1N1  B 601 ( 4.9A) 1N1  B 601 (-3.5A) 1N1  B 601 (-3.3A) 1N1  B 601 ( 4.2A) None 1N1  B 601 (-3.5A) None 1N1  B 601 (-4.3A) 1N1  B 601 (-3.5A)	0.48A	78.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	9 / 12	VAL B 275 ALA B 288 THR B 334 PHE B 336 MET B 337 GLY B 340 LEU B 389 ALA B 399 PHE B 401	1N1  B 601 ( 4.9A) 1N1  B 601 (-3.5A) 1N1  B 601 (-3.3A) 1N1  B 601 ( 4.2A) None 1N1  B 601 (-3.5A) 1N1  B 601 (-4.3A) 1N1  B 601 (-3.5A) None	1.09A	78.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	4yff	SERINE/THREONINE-PRO TEIN KINASE TNNI3K (Homo sapiens)	7 / 12	VAL A 477 ALA A 488 LYS A 490 THR A 539 GLY A 545 LEU A 595 ALA A 605	None 4CV  A 801 (-3.5A) 4CV  A 801 (-3.9A) 4CV  A 801 (-2.8A) 4CV  A 801 ( 4.0A) 4CV  A 801 (-4.4A) 4CV  A 801 ( 3.9A)	0.72A	28.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5e8y	TGF-BETA RECEPTOR TYPE-2 (Homo sapiens)	7 / 12	VAL A 258 ALA A 275 LYS A 277 THR A 325 PHE A 327 GLY A 331 LEU A 386	STU  A 601 (-4.0A) STU  A 601 (-3.1A) STU  A 601 (-2.4A) STU  A 601 ( 3.7A) STU  A 601 (-3.4A) STU  A 601 (-3.5A) STU  A 601 (-3.9A)	0.86A	27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5e8y	TGF-BETA RECEPTOR TYPE-2 (Homo sapiens)	7 / 12	VAL A 258 ALA A 275 THR A 325 PHE A 327 GLY A 331 ASN A 384 LEU A 386	STU  A 601 (-4.0A) STU  A 601 (-3.1A) STU  A 601 ( 3.7A) STU  A 601 (-3.4A) STU  A 601 (-3.5A) STU  A 601 ( 4.9A) STU  A 601 (-3.9A)	0.63A	27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5iso	5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 (Homo sapiens)	7 / 12	VAL A  30 ALA A  43 LYS A  45 GLY A  99 ASN A 144 LEU A 146 ALA A 156	STU  A 601 (-4.8A) STU  A 601 (-3.3A) STU  A 601 ( 4.4A) STU  A 601 ( 4.0A) STU  A 601 (-4.3A) STU  A 601 (-4.5A) STU  A 601 (-3.5A)	0.77A	19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	7 / 12	VAL A  30 ALA A  43 LYS A  45 PHE A  92 GLY A  96 LEU A 143 ALA A 153	6G2  A 901 ( 4.9A) 6G2  A 901 (-3.2A) 6G2  A 901 ( 3.9A) 6G2  A 901 (-4.1A) 6G2  A 901 (-3.6A) 6G2  A 901 (-4.7A) 6G2  A 901 ( 4.2A)	0.69A	24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	7 / 12	VAL A  30 ALA A  43 PHE A  92 GLY A  96 ASN A 141 LEU A 143 ALA A 153	6G2  A 901 ( 4.9A) 6G2  A 901 (-3.2A) 6G2  A 901 (-4.1A) 6G2  A 901 (-3.6A) None 6G2  A 901 (-4.7A) 6G2  A 901 ( 4.2A)	0.62A	24.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5l6o	EPHRIN TYPE-B RECEPTOR 3 (Homo sapiens)	7 / 12	ALA A 663 THR A 711 PHE A 713 MET A 714 ASN A 763 LEU A 765 PHE A 777	6P6  A1001 (-3.3A) 6P6  A1001 (-3.5A) 6P6  A1001 ( 4.5A) None None 6P6  A1001 (-4.5A) DIO  A1002 (-4.5A)	1.30A	38.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5l6o	EPHRIN TYPE-B RECEPTOR 3 (Homo sapiens)	7 / 12	VAL A 647 ALA A 663 LYS A 665 PHE A 713 MET A 714 ASN A 763 LEU A 765	None 6P6  A1001 (-3.3A) None 6P6  A1001 ( 4.5A) None None 6P6  A1001 (-4.5A)	0.78A	38.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5l6o	EPHRIN TYPE-B RECEPTOR 3 (Homo sapiens)	7 / 12	VAL A 647 ALA A 663 THR A 711 PHE A 713 MET A 714 ASN A 763 LEU A 765	None 6P6  A1001 (-3.3A) 6P6  A1001 (-3.5A) 6P6  A1001 ( 4.5A) None None 6P6  A1001 (-4.5A)	0.62A	38.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	7 / 12	VAL A 601 ALA A 617 PHE A 673 MET A 674 GLY A 677 ASN A 728 ALA A 740	7AE  A1000 ( 4.9A) 7AE  A1000 (-3.3A) 7AE  A1000 (-4.1A) None 7AE  A1000 ( 3.7A) 7AE  A1000 (-4.7A) 7AE  A1000 ( 3.7A)	0.61A	42.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5u6b	TYROSINE-PROTEIN KINASE RECEPTOR UFO (Homo sapiens)	7 / 12	VAL A 550 ALA A 565 LYS A 567 PHE A 622 MET A 623 GLY A 626 ALA A 689	7YS  A9001 (-4.2A) 7YS  A9001 (-3.3A) None 7YS  A9001 (-4.3A) 7YS  A9001 (-4.7A) 7YS  A9001 (-3.4A) 7YS  A9001 (-3.4A)	0.77A	43.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5u6b	TYROSINE-PROTEIN KINASE RECEPTOR UFO (Homo sapiens)	7 / 12	VAL A 550 ALA A 565 PHE A 622 MET A 623 GLY A 626 ASN A 677 ALA A 689	7YS  A9001 (-4.2A) 7YS  A9001 (-3.3A) 7YS  A9001 (-4.3A) 7YS  A9001 (-4.7A) 7YS  A9001 (-3.4A) None 7YS  A9001 (-3.4A)	0.78A	43.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	5w5j	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2 (Homo sapiens)	8 / 12	VAL A  32 ALA A  45 THR A  95 MET A  98 GLY A 101 ASN A 151 LEU A 153 ALA A 163	9WS  A 401 ( 4.6A) 9WS  A 401 (-3.3A) 9WS  A 401 (-3.2A) None 9WS  A 401 ( 4.3A) None 9WS  A 401 (-4.6A) 9WS  A 401 ( 4.0A)	0.64A	27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 LYS A 194 GLY A 273 ASN A 317 LEU A 319 ALA A 329	F6J  A 501 (-4.6A) F6J  A 501 (-3.4A) F6J  A 501 (-2.9A) F6J  A 501 ( 3.7A) F6J  A 501 ( 4.7A) F6J  A 501 (-4.5A) F6J  A 501 ( 4.0A)	0.73A	14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	6cz4	PROTEIN-TYROSINE KINASE 6 (Homo sapiens)	7 / 12	VAL A 205 ALA A 217 THR A 264 MET A 267 GLY A 270 ASN A 317 LEU A 319	FKY  A9001 ( 4.6A) FKY  A9001 (-3.3A) FKY  A9001 (-3.0A) None FKY  A9001 (-3.3A) None FKY  A9001 ( 4.9A)	0.94A	18.41