POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1k2p	TYROSINE-PROTEIN KINASE BTK (Homo sapiens)	7 / 12	ALA A 428 LYS A 430 THR A 474 MET A 477 GLY A 480 LEU A 528 ASP A 539	None	0.57A	32.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1py5	TGF-BETA RECEPTOR TYPE I (Homo sapiens)	7 / 12	ALA A 230 LYS A 232 GLU A 245 LEU A 278 GLY A 286 LEU A 340 ASP A 351	PY1  A 700 (-3.5A) PY1  A 700 (-3.9A) PY1  A 700 ( 4.9A) PY1  A 700 (-3.8A) PY1  A 700 (-3.6A) PY1  A 700 (-4.4A) PY1  A 700 (-2.7A)	0.45A	25.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1t46	HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG (Homo sapiens)	7 / 12	LEU A 595 ALA A 621 LYS A 623 GLU A 640 THR A 670 GLY A 676 LEU A 799	STI  A   3 ( 3.8A) STI  A   3 (-3.5A) STI  A   3 (-3.7A) STI  A   3 (-3.6A) STI  A   3 (-3.2A) STI  A   3 ( 3.8A) STI  A   3 (-4.4A)	0.68A	31.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1zlt	SERINE/THREONINE-PRO TEIN KINASE CHK1 (Homo sapiens)	7 / 12	LEU A  15 ALA A  36 LYS A  38 GLU A  55 LEU A  82 GLY A  90 LEU A 137	HYM  A 400 (-4.2A) HYM  A 400 (-3.5A) HYM  A 400 (-3.2A) None None None HYM  A 400 (-4.5A)	0.70A	25.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 12	LEU X  17 ALA X  37 LYS X  39 GLU X  54 THR X  82 MET X  85 ASP X 148	STU  X 902 (-3.8A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) STU  X 902 ( 4.4A) STU  X 902 (-4.1A) None STU  X 902 (-3.6A)	0.77A	32.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	8 / 12	LEU X  17 ALA X  37 LYS X  39 GLU X  54 THR X  82 MET X  85 GLY X  88 LEU X 137	STU  X 902 (-3.8A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) STU  X 902 ( 4.4A) STU  X 902 (-4.1A) None STU  X 902 (-3.5A) STU  X 902 (-4.4A)	0.59A	32.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2h8h	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	7 / 12	LEU A 273 ALA A 293 LYS A 295 THR A 338 MET A 341 GLY A 344 LEU A 393	H8H  A 534 (-3.8A) H8H  A 534 (-3.2A) H8H  A 534 (-3.7A) H8H  A 534 (-3.1A) None H8H  A 534 (-3.3A) H8H  A 534 (-4.5A)	0.50A	22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	7 / 12	LEU A 273 ALA A 293 LYS A 295 THR A 338 MET A 341 GLY A 344 LEU A 393	QUE  A   1 (-3.9A) QUE  A   1 (-3.5A) None QUE  A   1 (-3.3A) None QUE  A   1 (-3.0A) QUE  A   1 (-4.4A)	0.70A	27.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	8 / 12	LEU A 251 ALA A 271 LYS A 273 GLU A 288 THR A 316 MET A 319 GLY A 322 LEU A 371	1BM  A 499 ( 3.7A) 1BM  A 499 (-3.6A) 1BM  A 499 (-3.8A) 1BM  A 499 (-3.2A) 1BM  A 499 (-3.2A) None 1BM  A 499 (-3.5A) 1BM  A 499 (-4.4A)	0.44A	34.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	LEU A 248 ALA A 269 LYS A 271 GLU A 286 THR A 315 MET A 318 GLY A 321 LEU A 370	GIN  A 600 ( 4.6A) GIN  A 600 (-3.1A) GIN  A 600 (-3.6A) GIN  A 600 (-3.6A) GIN  A 600 (-3.4A) None None GIN  A 600 (-4.7A)	0.70A	36.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	8 / 12	LEU A 251 ALA A 271 LYS A 273 GLU A 288 THR A 316 MET A 319 GLY A 322 LEU A 371	None 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.6A) 1N8  A 501 ( 3.3A) 1N8  A 501 ( 4.4A) 1N8  A 501 ( 3.5A) 1N8  A 501 ( 4.3A)	0.76A	33.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2qlu	ACTIVIN RECEPTOR TYPE IIB (Homo sapiens)	8 / 12	ALA A 215 LYS A 217 GLU A 230 LEU A 263 THR A 265 GLY A 271 LEU A 328 ASP A 339	ADE  A 488 (-3.2A) None None None ADE  A 488 (-4.3A) ADE  A 488 ( 4.1A) ADE  A 488 (-4.4A) None	0.68A	25.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2r4b	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	10 / 12	LEU A 724 ALA A 749 LYS A 751 LEU A 794 THR A 796 LEU A 798 MET A 799 GLY A 802 LEU A 850 THR A 860	GW7  A   1 ( 4.2A) GW7  A   1 (-3.3A) GW7  A   1 (-3.9A) GW7  A   1 (-4.1A) GW7  A   1 (-4.0A) GW7  A   1 (-4.5A) None GW7  A   1 (-3.6A) GW7  A   1 (-4.2A) GW7  A   1 (-3.5A)	0.75A	75.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2r4b	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	10 / 12	LEU A 724 ALA A 749 LYS A 751 LEU A 794 THR A 796 LEU A 798 MET A 799 LEU A 850 THR A 860 ASP A 861	GW7  A   1 ( 4.2A) GW7  A   1 (-3.3A) GW7  A   1 (-3.9A) GW7  A   1 (-4.1A) GW7  A   1 (-4.0A) GW7  A   1 (-4.5A) None GW7  A   1 (-4.2A) GW7  A   1 (-3.5A) GW7  A   1 (-4.1A)	0.87A	75.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2w4k	DEATH-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	7 / 12	LEU A  19 ALA A  40 LYS A  42 GLU A  64 LEU A  91 LEU A  95 ASP A 161	ADP  A1303 ( 3.9A) ADP  A1303 (-3.5A) ADP  A1303 (-2.7A) ADP  A1303 ( 4.8A) None None MG  A1304 ( 2.8A)	0.77A	25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2wnt	RIBOSOMAL PROTEIN S6 KINASE (Homo sapiens)	7 / 12	ALA A 445 LYS A 447 GLU A 459 LEU A 487 THR A 489 LEU A 491 MET A 492	None	0.62A	24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2xk9	CHECKPOINT KINASE 2 (Homo sapiens)	8 / 12	LEU A 226 ALA A 247 LYS A 249 LEU A 303 MET A 304 GLY A 307 LEU A 354 THR A 367	XK9  A1511 (-3.8A) XK9  A1511 ( 4.1A) XK9  A1511 (-4.2A) XK9  A1511 (-4.1A) None XK9  A1511 ( 3.7A) XK9  A1511 (-4.6A) XK9  A1511 (-3.7A)	0.85A	27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2y7j	PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM (Homo sapiens)	8 / 12	ALA A  51 LYS A  53 LEU A 105 LEU A 109 MET A 110 GLY A 113 LEU A 160 ASP A 171	B49  A1294 (-3.2A) None None B49  A1294 ( 4.7A) None B49  A1294 (-3.6A) B49  A1294 (-4.4A) B49  A1294 (-4.2A)	0.49A	23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2y7j	PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM (Homo sapiens)	7 / 12	LYS A  53 GLU A  77 LEU A 109 MET A 110 GLY A 113 LEU A 160 ASP A 171	None None B49  A1294 ( 4.7A) None B49  A1294 (-3.6A) B49  A1294 (-4.4A) B49  A1294 (-4.2A)	0.74A	23.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2z8c	INSULIN RECEPTOR (Homo sapiens)	8 / 12	LEU A1002 ALA A1028 LYS A1030 GLU A1047 LEU A1078 MET A1079 GLY A1082 ASP A1150	S91  A   1 ( 4.1A) S91  A   1 (-3.2A) S91  A   1 ( 4.2A) None S91  A   1 (-4.7A) None S91  A   1 (-3.3A) None	0.82A	32.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	7 / 12	ALA A 220 LYS A 222 GLU A 236 THR A 266 MET A 269 GLY A 272 LEU A 321	None	0.49A	34.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3fzp	PROTEIN TYROSINE KINASE 2 BETA (Homo sapiens)	7 / 12	LEU A 431 ALA A 455 LYS A 457 GLU A 474 LEU A 504 GLY A 508 LEU A 556	AGS  A 999 ( 4.4A) AGS  A 999 (-3.6A) AGS  A 999 (-2.5A) AGS  A 999 (-3.6A) AGS  A 999 (-4.4A) None AGS  A 999 (-4.5A)	0.89A	34.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3i6u	SERINE/THREONINE-PRO TEIN KINASE CHK2 (Homo sapiens)	7 / 12	ALA A 247 LEU A 303 MET A 304 GLY A 307 LEU A 354 THR A 367 ASP A 368	None	0.75A	21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3i6u	SERINE/THREONINE-PRO TEIN KINASE CHK2 (Homo sapiens)	7 / 12	LEU A 226 ALA A 247 LEU A 303 MET A 304 LEU A 354 THR A 367 ASP A 368	None	0.71A	21.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3kex	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3 (Homo sapiens)	7 / 12	LEU A 696 LYS A 723 LEU A 766 THR A 768 GLY A 774 LEU A 822 ASP A 833	ANP  A   1 (-4.4A) ANP  A   1 (-3.4A) None ANP  A   1 ( 4.8A) ANP  A   1 ( 4.9A) ANP  A   1 (-4.7A) MG  A1001 ( 3.1A)	0.84A	54.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3kmu	INTEGRIN-LINKED KINASE (Homo sapiens)	7 / 12	LEU A 199 LYS A 220 LEU A 267 THR A 269 MET A 272 GLY A 275 ASP A 339	None	0.88A	24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3kul	EPHRIN TYPE-A RECEPTOR 8 (Homo sapiens)	7 / 12	ALA A 665 LYS A 667 GLU A 684 THR A 713 MET A 716 GLY A 719 LEU A 767	None None None None None GOL  A 403 (-3.4A) None	0.67A	32.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3lm5	SERINE/THREONINE-PRO TEIN KINASE 17B (Homo sapiens)	7 / 12	LEU A  39 ALA A  60 LYS A  62 LEU A 108 GLY A 116 LEU A 165 ASP A 179	QUE  A   1 ( 3.8A) QUE  A   1 (-3.2A) QUE  A   1 (-4.1A) None None None QUE  A   1 (-2.9A)	0.93A	24.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3lzb	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	7 / 12	ALA A 719 LEU A 764 THR A 766 LEU A 768 GLY A 772 LEU A 820 THR A 830	ITI  A   1 (-2.9A) ITI  A   1 ( 4.2A) ITI  A   1 (-3.8A) ITI  A   1 (-4.8A) ITI  A   1 (-3.5A) ITI  A   1 (-4.6A) ITI  A   1 (-3.8A)	1.00A	86.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3lzb	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	7 / 12	ALA A 719 THR A 766 LEU A 768 GLY A 772 LEU A 820 THR A 830 ASP A 831	ITI  A   1 (-2.9A) ITI  A   1 (-3.8A) ITI  A   1 (-4.8A) ITI  A   1 (-3.5A) ITI  A   1 (-4.6A) ITI  A   1 (-3.8A) ITI  A   1 ( 4.6A)	0.83A	86.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3lzb	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	7 / 12	LEU A 694 ALA A 719 THR A 766 LEU A 768 GLY A 772 THR A 830 ASP A 831	ITI  A   1 (-3.9A) ITI  A   1 (-2.9A) ITI  A   1 (-3.8A) ITI  A   1 (-4.8A) ITI  A   1 (-3.5A) ITI  A   1 (-3.8A) ITI  A   1 ( 4.6A)	0.96A	86.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3mdy	BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B (Homo sapiens)	7 / 12	ALA A 229 LYS A 231 GLU A 244 LEU A 277 THR A 279 GLY A 285 LEU A 339	LDN  A   1 (-3.6A) None None None LDN  A   1 (-3.8A) LDN  A   1 (-3.3A) LDN  A   1 (-4.5A)	0.66A	25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3my0	SERINE/THREONINE-PRO TEIN KINASE RECEPTOR R3 (Homo sapiens)	7 / 12	ALA A 227 LYS A 229 GLU A 242 LEU A 275 THR A 277 GLY A 283 LEU A 337	LDN  A 600 (-3.2A) LDN  A 600 (-4.0A) None None LDN  A 600 (-4.0A) LDN  A 600 (-3.3A) LDN  A 600 (-4.6A)	0.81A	26.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	9 / 12	LEU A 192 ALA A 213 LYS A 215 GLU A 234 LEU A 261 LEU A 265 MET A 266 GLY A 269 LEU A 318	AMP  A 577 ( 4.3A) AMP  A 577 (-3.4A) AMP  A 577 (-2.8A) None None AMP  A 577 ( 4.9A) None None AMP  A 577 (-4.8A)	0.54A	19.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	7 / 12	ALA A 751 LEU A 796 THR A 798 LEU A 800 MET A 801 THR A 862 ASP A 863	03Q  A   1 (-3.1A) 03Q  A   1 (-4.3A) 03Q  A   1 (-4.1A) 03Q  A   1 (-4.6A) None 03Q  A   1 (-3.3A) 03Q  A   1 (-4.0A)	0.83A	78.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	10 / 12	LEU A 726 ALA A 751 LYS A 753 LEU A 796 THR A 798 LEU A 800 MET A 801 GLY A 804 LEU A 852 THR A 862	03Q  A   1 (-3.8A) 03Q  A   1 (-3.1A) 03Q  A   1 (-4.7A) 03Q  A   1 (-4.3A) 03Q  A   1 (-4.1A) 03Q  A   1 (-4.6A) None 03Q  A   1 ( 3.9A) 03Q  A   1 (-4.4A) 03Q  A   1 (-3.3A)	0.69A	78.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3wig	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 (Homo sapiens)	7 / 12	LEU A  75 ALA A  96 LYS A  98 MET A 147 GLY A 150 LEU A 198 ASP A 209	ANP  A 401 (-3.8A) ANP  A 401 (-3.2A) ANP  A 401 (-2.7A) None ANP  A 401 ( 4.3A) ANP  A 401 (-4.8A) MG  A 402 (-3.2A)	0.88A	26.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	7 / 12	LEU A1951 ALA A1978 LYS A1980 LEU A2028 MET A2029 GLY A2032 LEU A2086	VGH  A3000 ( 4.4A) VGH  A3000 (-3.4A) VGH  A3000 ( 4.7A) VGH  A3000 ( 4.8A) None VGH  A3000 (-3.5A) VGH  A3000 (-4.3A)	0.35A	34.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3zfx	EPHRIN TYPE-B RECEPTOR 1 (Homo sapiens)	8 / 12	ALA A 649 LYS A 651 GLU A 668 THR A 697 MET A 700 GLY A 703 LEU A 751 ASP A 762	None	0.72A	36.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4aw5	EPHRIN TYPE-B RECEPTOR 4 (Homo sapiens)	8 / 12	ALA A 121 LYS A 123 GLU A 140 THR A 169 MET A 172 GLY A 175 LEU A 223 ASP A 234	30K  A1365 (-3.2A) 30K  A1365 (-3.8A) None 30K  A1365 (-3.8A) None 30K  A1365 (-3.5A) 30K  A1365 (-4.5A) 30K  A1365 (-3.3A)	0.74A	33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4c02	ACTIVIN RECEPTOR TYPE-1 (Homo sapiens)	7 / 12	ALA A 233 GLU A 248 LEU A 281 THR A 283 GLY A 289 LEU A 343 ASP A 354	TAK  A1507 (-3.3A) None None TAK  A1507 (-3.6A) TAK  A1507 (-3.5A) TAK  A1507 (-4.7A) TAK  A1507 (-3.5A)	0.78A	24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4c02	ACTIVIN RECEPTOR TYPE-1 (Homo sapiens)	7 / 12	ALA A 233 LYS A 235 LEU A 281 THR A 283 GLY A 289 LEU A 343 ASP A 354	TAK  A1507 (-3.3A) TAK  A1507 ( 4.5A) None TAK  A1507 (-3.6A) TAK  A1507 (-3.5A) TAK  A1507 (-4.7A) TAK  A1507 (-3.5A)	0.68A	24.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	7 / 12	LEU A 616 ALA A 653 LYS A 655 GLU A 672 THR A 701 MET A 704 LEU A 773	None DI1  A1000 (-3.6A) DI1  A1000 (-3.9A) DI1  A1000 (-3.8A) DI1  A1000 (-3.6A) None DI1  A1000 (-4.5A)	0.83A	33.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4f4p	TYROSINE-PROTEIN KINASE SYK (Homo sapiens)	8 / 12	LEU A 377 ALA A 400 LYS A 402 GLU A 420 LEU A 446 GLY A 454 LEU A 501 ASP A 512	0SB  A 701 ( 3.9A) 0SB  A 701 (-3.3A) 0SB  A 701 ( 4.8A) None None 0SB  A 701 (-3.5A) 0SB  A 701 (-4.4A) 0SB  A 701 (-3.9A)	0.68A	39.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4fl3	TYROSINE-PROTEIN KINASE SYK (Homo sapiens)	7 / 12	LEU A 377 ALA A 400 LYS A 402 LEU A 446 GLY A 454 LEU A 501 ASP A 512	ANP  A 701 ( 4.6A) ANP  A 701 (-3.3A) ANP  A 701 (-2.7A) None ANP  A 701 ( 4.2A) ANP  A 701 (-4.5A) MG  A 702 ( 3.1A)	0.87A	20.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	7 / 12	LEU A1122 ALA A1148 GLU A1167 LEU A1198 MET A1199 GLY A1202 LEU A1256	0UV  A1501 (-3.8A) 0UV  A1501 (-3.4A) None 0UV  A1501 ( 4.8A) None 0UV  A1501 (-3.6A) 0UV  A1501 (-4.6A)	0.44A	31.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	7 / 12	LEU A1122 ALA A1148 LYS A1150 GLU A1167 LEU A1198 GLY A1202 LEU A1256	0UV  A1501 (-3.8A) 0UV  A1501 (-3.4A) 0UV  A1501 (-3.7A) None 0UV  A1501 ( 4.8A) 0UV  A1501 (-3.6A) 0UV  A1501 (-4.6A)	0.83A	31.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 ALA A 853 LYS A 855 GLU A 871 LEU A 900 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.88A	34.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hzs	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	8 / 12	LEU A 132 ALA A 156 LYS A 158 THR A 205 LEU A 207 GLY A 211 LEU A 259 ASP A 270	None	0.72A	35.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4id7	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	7 / 12	LEU A 132 ALA A 156 GLU A 177 THR A 205 LEU A 207 GLY A 211 LEU A 259	1G0  A 401 ( 4.5A) 1G0  A 401 (-3.6A) 1G0  A 401 ( 4.5A) 1G0  A 401 (-3.2A) 1G0  A 401 ( 4.9A) 1G0  A 401 ( 4.5A) 1G0  A 401 (-4.6A)	0.96A	35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4id7	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	7 / 12	LEU A 132 ALA A 156 LYS A 158 THR A 205 LEU A 207 GLY A 211 LEU A 259	1G0  A 401 ( 4.5A) 1G0  A 401 (-3.6A) 1G0  A 401 (-3.7A) 1G0  A 401 (-3.2A) 1G0  A 401 ( 4.9A) 1G0  A 401 ( 4.5A) 1G0  A 401 (-4.6A)	0.53A	35.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4k11	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	7 / 12	LEU A 273 ALA A 293 LYS A 295 MET A 341 GLY A 344 LEU A 393 ASP A 404	0J9  A 601 (-4.0A) 0J9  A 601 (-3.3A) 0J9  A 601 ( 4.7A) None 0J9  A 601 ( 4.1A) 0J9  A 601 (-4.5A) 0J9  A 601 (-3.1A)	0.77A	25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	9 / 12	LEU A  46 ALA A  67 LYS A  69 GLU A  85 LEU A 121 THR A 123 LEU A 125 GLY A 128 LEU A 180	SIN  A 401 ( 3.9A) SIN  A 401 ( 3.7A) None None None None SIN  A 401 ( 4.8A) SIN  A 401 (-3.5A) SIN  A 401 ( 4.5A)	0.63A	22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4oli	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	7 / 12	LEU A 903 ALA A 928 LYS A 930 GLU A 947 LEU A 976 GLY A 984 LEU A1030	2TT  A1202 (-3.5A) 2TT  A1202 ( 3.9A) None None None 2TT  A1202 (-3.4A) 2TT  A1202 (-4.4A)	0.99A	20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4tnb	G PROTEIN-COUPLED RECEPTOR KINASE 5 (Homo sapiens)	8 / 12	LEU A 192 ALA A 213 LYS A 215 GLU A 234 LEU A 261 MET A 266 LEU A 318 ASP A 329	SGV  A 601 (-4.1A) SGV  A 601 (-3.3A) SGV  A 601 ( 4.2A) None None None SGV  A 601 (-4.9A) SGV  A 601 (-3.0A)	0.71A	21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4tnb	G PROTEIN-COUPLED RECEPTOR KINASE 5 (Homo sapiens)	7 / 12	LEU A 192 LYS A 215 GLU A 234 MET A 266 GLY A 269 LEU A 318 ASP A 329	SGV  A 601 (-4.1A) SGV  A 601 ( 4.2A) None None None SGV  A 601 (-4.9A) SGV  A 601 (-3.0A)	0.98A	21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	7 / 12	LEU B 267 ALA B 288 LYS B 290 THR B 334 MET B 337 GLY B 340 LEU B 389	1N1  B 601 (-3.7A) 1N1  B 601 (-3.5A) 1N1  B 601 (-4.6A) 1N1  B 601 (-3.3A) None 1N1  B 601 (-3.5A) 1N1  B 601 (-4.3A)	0.42A	28.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4xuf	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	7 / 12	LEU A 616 ALA A 642 LYS A 644 GLU A 661 LEU A 689 GLY A 697 LEU A 818	P30  A1001 (-4.0A) P30  A1001 (-3.5A) P30  A1001 ( 4.0A) P30  A1001 (-3.1A) None P30  A1001 (-3.5A) P30  A1001 (-4.3A)	0.70A	32.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4yhj	G PROTEIN-COUPLED RECEPTOR KINASE 4 (Homo sapiens)	7 / 12	LEU A 193 ALA A 214 LYS A 216 GLU A 235 LEU A 262 MET A 267 LEU A 319	AN2  A 601 ( 4.2A) AN2  A 601 (-3.6A) AN2  A 601 ( 3.9A) None None None None	0.62A	22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4z7g	SERINE/THREONINE-PRO TEIN KINASE/ENDORIBONUCLE ASE IRE1 (Homo sapiens)	7 / 12	LEU A 577 ALA A 597 LYS A 599 GLU A 612 LEU A 644 LEU A 695 ASP A 711	None	0.94A	25.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5a46	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens)	7 / 12	LEU A 484 ALA A 512 LYS A 514 GLU A 531 GLY A 567 LEU A 630 ASP A 641	38O  A1769 (-3.2A) 38O  A1769 (-3.6A) 38O  A1769 ( 3.1A) EDO  A1766 (-4.1A) 38O  A1769 (-3.4A) 38O  A1769 (-4.6A) 38O  A1769 (-4.0A)	0.61A	33.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5ci7	SERINE/THREONINE-PRO TEIN KINASE ULK1 (Homo sapiens)	7 / 12	ALA A  44 LYS A  46 GLU A  63 LEU A  90 GLY A  98 LEU A 145 ASP A 165	51W  A 401 (-3.4A) GOL  A 404 ( 3.1A) None None 51W  A 401 (-3.7A) 51W  A 401 (-4.5A) GOL  A 404 (-3.2A)	0.81A	27.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5e8y	TGF-BETA RECEPTOR TYPE-2 (Homo sapiens)	7 / 12	ALA A 275 LYS A 277 GLU A 290 LEU A 323 THR A 325 GLY A 331 LEU A 386	STU  A 601 (-3.1A) STU  A 601 (-2.4A) STU  A 601 ( 3.8A) None STU  A 601 ( 3.7A) STU  A 601 (-3.5A) STU  A 601 (-3.9A)	0.49A	25.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5f1z	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	7 / 12	LEU A 903 ALA A 928 LYS A 930 GLU A 947 LEU A 976 GLY A 984 LEU A1030	5U3  A1200 (-3.8A) 5U3  A1200 (-3.5A) None None None 5U3  A1200 (-3.2A) 5U3  A1200 (-4.4A)	0.81A	31.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	7 / 12	LEU A 599 ALA A 625 LYS A 627 GLU A 644 THR A 674 GLY A 680 LEU A 825	748  A1001 (-3.8A) 748  A1001 (-3.7A) 748  A1001 (-4.0A) 748  A1001 (-3.3A) 748  A1001 (-3.2A) 748  A1001 ( 4.0A) 748  A1001 (-4.3A)	0.63A	31.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5j9z	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	11 / 12	LEU A 718 ALA A 743 LYS A 745 GLU A 762 LEU A 788 LEU A 792 MET A 793 GLY A 796 LEU A 844 THR A 854 ASP A 855	6HJ  A1101 ( 4.6A) 6HJ  A1101 (-3.1A) 6HJ  A1101 (-4.2A) 6HJ  A1101 ( 4.2A) 6HJ  A1101 ( 4.6A) 6HJ  A1101 ( 4.9A) None 6HJ  A1101 ( 4.5A) 6HJ  A1101 ( 4.8A) 6HJ  A1101 (-3.9A) 6HJ  A1101 (-4.3A)	0.38A	97.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5jzn	SERINE/THREONINE-PRO TEIN KINASE DCLK1 (Homo sapiens)	7 / 12	ALA A 417 LYS A 419 GLU A 436 LEU A 463 LEU A 467 GLY A 471 LEU A 518	GUI  A 701 ( 3.9A) GUI  A 701 (-3.1A) None None GUI  A 701 ( 4.7A) GUI  A 701 (-3.6A) GUI  A 701 (-4.4A)	0.76A	26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5vcx	MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE (Homo sapiens)	7 / 12	LEU A 116 ALA A 137 GLU A 157 LEU A 185 THR A 187 LEU A 189 ASP A 251	H8H  A 401 (-3.7A) H8H  A 401 (-3.3A) None H8H  A 401 (-4.3A) H8H  A 401 (-3.5A) None EDO  A 402 ( 2.9A)	0.75A	22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5vcx	MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE (Homo sapiens)	7 / 12	LEU A 116 ALA A 137 LYS A 139 GLU A 157 LEU A 185 THR A 187 LEU A 189	H8H  A 401 (-3.7A) H8H  A 401 (-3.3A) H8H  A 401 (-4.9A) None H8H  A 401 (-4.3A) H8H  A 401 (-3.5A) None	0.89A	22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	6bfn	INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1 (Homo sapiens)	7 / 12	ALA A 237 LYS A 239 GLU A 259 LEU A 286 GLY A 294 LEU A 347 ASP A 358	DL1  A 601 (-3.4A) DL1  A 601 ( 4.1A) None None DL1  A 601 (-3.5A) DL1  A 601 (-3.9A) DL1  A 601 (-3.1A)	0.84A	14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	6c7y	TYROSINE-PROTEIN KINASE JAK1 (Homo sapiens)	7 / 12	LEU A 881 ALA A 906 LYS A 908 GLU A 925 LEU A 954 GLY A 962 LEU A1010	ADP  A1201 ( 4.5A) ADP  A1201 (-3.4A) ADP  A1201 (-2.8A) None None ADP  A1201 ( 4.1A) ADP  A1201 (-4.5A)	0.73A	14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M17_A_AQ4A999_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	6cz4	PROTEIN-TYROSINE KINASE 6 (Homo sapiens)	8 / 12	LEU A 197 ALA A 217 LYS A 219 THR A 264 LEU A 266 MET A 267 GLY A 270 LEU A 319	FKY  A9001 (-4.1A) FKY  A9001 (-3.3A) None FKY  A9001 (-3.0A) FKY  A9001 (-4.4A) None FKY  A9001 (-3.3A) FKY  A9001 ( 4.9A)	0.99A	17.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1k2p	TYROSINE-PROTEIN KINASE BTK (Homo sapiens)	7 / 12	ALA A 428 LYS A 430 THR A 474 MET A 477 GLY A 480 LEU A 528 ASP A 539	None	0.96A	32.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1k2p	TYROSINE-PROTEIN KINASE BTK (Homo sapiens)	7 / 12	ALA A 428 THR A 474 MET A 477 GLY A 480 CYH A 481 LEU A 528 ASP A 539	None	0.68A	32.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1k2p	TYROSINE-PROTEIN KINASE BTK (Homo sapiens)	7 / 12	LEU A 408 VAL A 416 LYS A 430 MET A 477 GLY A 480 LEU A 528 ASP A 539	None	1.10A	32.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1k2p	TYROSINE-PROTEIN KINASE BTK (Homo sapiens)	7 / 12	LEU A 408 VAL A 416 MET A 477 GLY A 480 CYH A 481 LEU A 528 ASP A 539	None	0.97A	32.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1k2p	TYROSINE-PROTEIN KINASE BTK (Homo sapiens)	7 / 12	VAL A 416 ALA A 428 LYS A 430 MET A 477 GLY A 480 LEU A 528 ASP A 539	None	0.99A	32.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1k2p	TYROSINE-PROTEIN KINASE BTK (Homo sapiens)	7 / 12	VAL A 416 ALA A 428 MET A 477 GLY A 480 CYH A 481 LEU A 528 ASP A 539	None	0.87A	32.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1s9i	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	LEU A  78 VAL A  86 ALA A  99 LYS A 101 MET A 150 GLY A 153 LEU A 201 ASP A 212	ATP  A 535 (-3.9A) ATP  A 535 (-4.1A) ATP  A 535 (-3.6A) ATP  A 535 ( 2.5A) None ATP  A 535 ( 4.7A) ATP  A 535 (-4.8A) MG  A 536 (-3.3A)	0.52A	26.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1snx	TYROSINE-PROTEIN KINASE ITK/TSK (Homo sapiens)	7 / 12	VAL A 377 ALA A 389 LYS A 391 GLY A 441 CYH A 442 LEU A 489 ASP A 500	None	0.81A	31.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1snx	TYROSINE-PROTEIN KINASE ITK/TSK (Homo sapiens)	7 / 12	VAL A 377 ALA A 389 LYS A 391 MET A 438 GLY A 441 CYH A 442 LEU A 489	None	0.71A	31.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1t46	HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG (Homo sapiens)	7 / 12	LEU A 595 VAL A 603 ALA A 621 LYS A 623 THR A 670 GLY A 676 LEU A 799	STI  A   3 ( 3.8A) STI  A   3 ( 4.6A) STI  A   3 (-3.5A) STI  A   3 (-3.7A) STI  A   3 (-3.2A) STI  A   3 ( 3.8A) STI  A   3 (-4.4A)	0.68A	31.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	1zlt	SERINE/THREONINE-PRO TEIN KINASE CHK1 (Homo sapiens)	7 / 12	LEU A  15 VAL A  23 ALA A  36 LYS A  38 GLY A  90 LEU A 137 ASP A 148	HYM  A 400 (-4.2A) HYM  A 400 (-4.3A) HYM  A 400 (-3.5A) HYM  A 400 (-3.2A) None HYM  A 400 (-4.5A) HYM  A 400 (-3.9A)	0.91A	24.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 12	LEU X  17 VAL X  25 ALA X  37 LYS X  39 MET X  85 LEU X 137 ASP X 148	STU  X 902 (-3.8A) STU  X 902 ( 4.8A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) None STU  X 902 (-4.4A) STU  X 902 (-3.6A)	0.96A	32.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 12	LEU X  17 VAL X  25 ALA X  37 LYS X  39 THR X  82 MET X  85 LEU X 137	STU  X 902 (-3.8A) STU  X 902 ( 4.8A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) STU  X 902 (-4.1A) None STU  X 902 (-4.4A)	0.77A	32.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 12	LEU X  17 VAL X  25 ALA X  37 MET X  85 GLY X  88 LEU X 137 ASP X 148	STU  X 902 (-3.8A) STU  X 902 ( 4.8A) STU  X 902 (-3.1A) None STU  X 902 (-3.5A) STU  X 902 (-4.4A) STU  X 902 (-3.6A)	0.65A	32.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 12	LEU X  17 VAL X  25 ALA X  37 THR X  82 MET X  85 GLY X  88 LEU X 137	STU  X 902 (-3.8A) STU  X 902 ( 4.8A) STU  X 902 (-3.1A) STU  X 902 (-4.1A) None STU  X 902 (-3.5A) STU  X 902 (-4.4A)	0.53A	32.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2h8h	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	9 / 12	LEU A 273 VAL A 281 ALA A 293 LYS A 295 THR A 338 MET A 341 GLY A 344 LEU A 393 ASP A 404	H8H  A 534 (-3.8A) H8H  A 534 (-4.4A) H8H  A 534 (-3.2A) H8H  A 534 (-3.7A) H8H  A 534 (-3.1A) None H8H  A 534 (-3.3A) H8H  A 534 (-4.5A) H8H  A 534 (-4.2A)	0.47A	22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	9 / 12	LEU A 273 VAL A 281 ALA A 293 LYS A 295 THR A 338 MET A 341 GLY A 344 LEU A 393 ASP A 404	QUE  A   1 (-3.9A) QUE  A   1 ( 4.8A) QUE  A   1 (-3.5A) None QUE  A   1 (-3.3A) None QUE  A   1 (-3.0A) QUE  A   1 (-4.4A) None	0.60A	26.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	7 / 12	LEU A 251 VAL A 259 ALA A 271 THR A 316 MET A 319 GLY A 322 LEU A 371	1BM  A 499 ( 3.7A) 1BM  A 499 ( 4.8A) 1BM  A 499 (-3.6A) 1BM  A 499 (-3.2A) None 1BM  A 499 (-3.5A) 1BM  A 499 (-4.4A)	0.35A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	LEU A 248 VAL A 256 ALA A 269 LYS A 271 THR A 315 MET A 318 GLY A 321 LEU A 370	GIN  A 600 ( 4.6A) GIN  A 600 ( 4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-3.6A) GIN  A 600 (-3.4A) None None GIN  A 600 (-4.7A)	0.69A	35.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	7 / 12	LEU A 251 ALA A 271 LYS A 273 THR A 316 MET A 319 GLY A 322 LEU A 371	None 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.3A) 1N8  A 501 ( 4.4A) 1N8  A 501 ( 3.5A) 1N8  A 501 ( 4.3A)	0.78A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	7 / 12	LEU A 251 VAL A 259 ALA A 271 LYS A 273 THR A 316 MET A 319 GLY A 322	None None 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.3A) 1N8  A 501 ( 4.4A) 1N8  A 501 ( 3.5A)	0.80A	33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2ozo	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	7 / 12	LEU A 344 VAL A 352 ALA A 367 LYS A 369 GLY A 418 LEU A 468 ASP A 479	ANP  A 615 (-4.4A) ANP  A 615 (-4.5A) ANP  A 615 (-3.3A) ANP  A 615 (-3.1A) ANP  A 615 ( 4.0A) ANP  A 615 (-4.7A) MG  A 614 ( 3.2A)	1.13A	20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2ozo	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	7 / 12	LEU A 344 VAL A 352 ALA A 367 LYS A 369 GLY A 420 LEU A 468 ASP A 479	ANP  A 615 (-4.4A) ANP  A 615 (-4.5A) ANP  A 615 (-3.3A) ANP  A 615 (-3.1A) ANP  A 615 ( 3.9A) ANP  A 615 (-4.7A) MG  A 614 ( 3.2A)	0.87A	20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2qlu	ACTIVIN RECEPTOR TYPE IIB (Homo sapiens)	7 / 12	VAL A 204 ALA A 215 LYS A 217 THR A 265 GLY A 271 LEU A 328 ASP A 339	ADE  A 488 ( 4.9A) ADE  A 488 (-3.2A) None ADE  A 488 (-4.3A) ADE  A 488 ( 4.1A) ADE  A 488 (-4.4A) None	0.65A	26.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2qob	EPHRIN RECEPTOR (Homo sapiens)	6 / 12	VAL A 635 ALA A 651 THR A 699 MET A 702 GLY A 705 LEU A 753	BME  A   1 (-4.9A) PTR  A 701 ( 4.7A) None PTR  A 701 ( 3.5A) None None	0.44A	33.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2r2p	EPHRIN TYPE-A RECEPTOR 5 (Homo sapiens)	6 / 12	VAL A 689 ALA A 705 THR A 753 MET A 756 GLY A 759 LEU A 807	None	0.45A	33.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2r4b	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	10 / 12	LEU A 724 VAL A 732 ALA A 749 LYS A 751 THR A 796 MET A 799 GLY A 802 LEU A 850 THR A 860 ASP A 861	GW7  A   1 ( 4.2A) GW7  A   1 ( 4.8A) GW7  A   1 (-3.3A) GW7  A   1 (-3.9A) GW7  A   1 (-4.0A) None GW7  A   1 (-3.6A) GW7  A   1 (-4.2A) GW7  A   1 (-3.5A) GW7  A   1 (-4.1A)	0.49A	76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2r4b	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	7 / 12	LYS A 751 MET A 799 GLY A 802 CYH A 803 LEU A 850 THR A 860 ASP A 861	GW7  A   1 (-3.9A) None GW7  A   1 (-3.6A) GW7  A   1 (-2.3A) GW7  A   1 (-4.2A) GW7  A   1 (-3.5A) GW7  A   1 (-4.1A)	0.84A	76.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2xk9	CHECKPOINT KINASE 2 (Homo sapiens)	8 / 12	LEU A 226 VAL A 234 ALA A 247 LYS A 249 MET A 304 GLY A 307 LEU A 354 THR A 367	XK9  A1511 (-3.8A) XK9  A1511 (-4.8A) XK9  A1511 ( 4.1A) XK9  A1511 (-4.2A) None XK9  A1511 ( 3.7A) XK9  A1511 (-4.6A) XK9  A1511 (-3.7A)	0.81A	26.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	7 / 12	LEU A  68 VAL A  76 ALA A  92 LYS A  94 GLY A 147 LEU A 194 THR A 204	STU  A   1 (-3.8A) None STU  A   1 (-3.3A) STU  A   1 (-2.8A) STU  A   1 ( 3.9A) STU  A   1 (-4.6A) STU  A   1 (-3.6A)	0.77A	26.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	7 / 12	LEU A  68 VAL A  76 ALA A  92 LYS A  94 GLY A 147 THR A 204 ASP A 205	STU  A   1 (-3.8A) None STU  A   1 (-3.3A) STU  A   1 (-2.8A) STU  A   1 ( 3.9A) STU  A   1 (-3.6A) STU  A   1 ( 3.8A)	0.93A	26.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	7 / 12	ALA A 220 LYS A 222 THR A 266 MET A 269 GLY A 272 LEU A 321 ASP A 332	None	0.92A	34.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	7 / 12	VAL A 209 ALA A 220 THR A 266 MET A 269 GLY A 272 LEU A 321 ASP A 332	None	0.66A	34.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3fzp	PROTEIN TYROSINE KINASE 2 BETA (Homo sapiens)	7 / 12	LEU A 431 VAL A 439 ALA A 455 LYS A 457 GLY A 508 LEU A 556 ASP A 567	AGS  A 999 ( 4.4A) AGS  A 999 (-4.6A) AGS  A 999 (-3.6A) AGS  A 999 (-2.5A) None AGS  A 999 (-4.5A) AGS  A 999 ( 3.9A)	0.87A	34.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3i6u	SERINE/THREONINE-PRO TEIN KINASE CHK2 (Homo sapiens)	7 / 12	LEU A 226 VAL A 234 ALA A 247 MET A 304 LEU A 354 THR A 367 ASP A 368	None	0.80A	21.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3kex	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3 (Homo sapiens)	7 / 12	LEU A 696 VAL A 704 LYS A 723 THR A 768 GLY A 774 LEU A 822 ASP A 833	ANP  A   1 (-4.4A) ANP  A   1 (-3.9A) ANP  A   1 (-3.4A) ANP  A   1 ( 4.8A) ANP  A   1 ( 4.9A) ANP  A   1 (-4.7A) MG  A1001 ( 3.1A)	0.53A	53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3kul	EPHRIN TYPE-A RECEPTOR 8 (Homo sapiens)	7 / 12	ALA A 665 LYS A 667 THR A 713 MET A 716 GLY A 719 LEU A 767 ASP A 778	None None None None GOL  A 403 (-3.4A) None None	0.96A	33.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3kul	EPHRIN TYPE-A RECEPTOR 8 (Homo sapiens)	7 / 12	VAL A 649 ALA A 665 THR A 713 MET A 716 GLY A 719 LEU A 767 ASP A 778	None None None None GOL  A 403 (-3.4A) None None	0.62A	33.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3lzb	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	8 / 12	ALA A 719 THR A 766 MET A 769 GLY A 772 CYH A 773 LEU A 820 THR A 830 ASP A 831	ITI  A   1 (-2.9A) ITI  A   1 (-3.8A) ITI  A   1 (-4.8A) ITI  A   1 (-3.5A) ITI  A   1 (-4.8A) ITI  A   1 (-4.6A) ITI  A   1 (-3.8A) ITI  A   1 ( 4.6A)	0.95A	88.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3lzb	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	8 / 12	VAL A 702 ALA A 719 THR A 766 MET A 769 CYH A 773 LEU A 820 THR A 830 ASP A 831	ITI  A   1 (-4.8A) ITI  A   1 (-2.9A) ITI  A   1 (-3.8A) ITI  A   1 (-4.8A) ITI  A   1 (-4.8A) ITI  A   1 (-4.6A) ITI  A   1 (-3.8A) ITI  A   1 ( 4.6A)	1.03A	88.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3nuu	PKB-LIKE (Homo sapiens)	7 / 12	LEU A  88 VAL A  96 ALA A 109 LYS A 111 GLY A 165 LEU A 212 THR A 222	JOZ  A 361 (-4.1A) JOZ  A 361 ( 4.7A) JOZ  A 361 (-3.4A) SO4  A   5 (-2.8A) None None JOZ  A 361 (-3.7A)	0.83A	27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	6 / 12	LEU A 192 VAL A 200 ALA A 213 MET A 266 GLY A 269 LEU A 318	AMP  A 577 ( 4.3A) AMP  A 577 (-4.3A) AMP  A 577 (-3.4A) None None AMP  A 577 (-4.8A)	0.49A	19.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	10 / 12	LEU A 726 VAL A 734 ALA A 751 LYS A 753 THR A 798 MET A 801 GLY A 804 LEU A 852 THR A 862 ASP A 863	03Q  A   1 (-3.8A) 03Q  A   1 (-4.5A) 03Q  A   1 (-3.1A) 03Q  A   1 (-4.7A) 03Q  A   1 (-4.1A) None 03Q  A   1 ( 3.9A) 03Q  A   1 (-4.4A) 03Q  A   1 (-3.3A) 03Q  A   1 (-4.0A)	0.75A	76.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	10 / 12	LEU A 726 VAL A 734 ALA A 751 THR A 798 MET A 801 GLY A 804 CYH A 805 LEU A 852 THR A 862 ASP A 863	03Q  A   1 (-3.8A) 03Q  A   1 (-4.5A) 03Q  A   1 (-3.1A) 03Q  A   1 (-4.1A) None 03Q  A   1 ( 3.9A) None 03Q  A   1 (-4.4A) 03Q  A   1 (-3.3A) 03Q  A   1 (-4.0A)	0.62A	76.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3q4t	ACTIVIN RECEPTOR TYPE-2A (Homo sapiens)	6 / 12	VAL A 206 ALA A 217 THR A 267 GLY A 273 LEU A 329 ASP A 340	TAK  A   2 ( 4.9A) TAK  A   2 (-3.5A) TAK  A   2 (-3.5A) TAK  A   2 (-3.6A) TAK  A   2 (-4.6A) None	0.57A	25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3she	MAP KINASE-ACTIVATED PROTEIN KINASE 3 (Homo sapiens)	7 / 12	LEU A  50 VAL A  58 ALA A  71 LYS A  73 MET A 121 LEU A 173 THR A 186	I85  A 350 (-3.7A) I85  A 350 (-4.9A) I85  A 350 (-3.3A) I85  A 350 (-2.8A) None None I85  A 350 ( 4.0A)	0.98A	23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3she	MAP KINASE-ACTIVATED PROTEIN KINASE 3 (Homo sapiens)	7 / 12	LEU A  50 VAL A  58 LYS A  73 MET A 121 LEU A 173 THR A 186 ASP A 187	I85  A 350 (-3.7A) I85  A 350 (-4.9A) I85  A 350 (-2.8A) None None I85  A 350 ( 4.0A) I85  A 350 (-3.3A)	1.08A	23.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3sxs	CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX (Homo sapiens)	8 / 12	LEU A 423 VAL A 431 ALA A 443 LYS A 445 THR A 489 GLY A 495 CYH A 496 LEU A 543	PP2  A   1 (-4.1A) PP2  A   1 (-4.5A) PP2  A   1 (-3.2A) PP2  A   1 (-4.5A) PP2  A   1 (-3.3A) PP2  A   1 ( 4.2A) None PP2  A   1 (-4.6A)	0.54A	30.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3v5q	NT-3 GROWTH FACTOR RECEPTOR (Homo sapiens)	6 / 12	LEU A 544 VAL A 552 ALA A 570 MET A 620 GLY A 623 LEU A 686	0F4  A 902 ( 4.2A) None 0F4  A 902 (-3.2A) None 0F4  A 902 (-3.4A) 0F4  A 902 (-4.5A)	0.46A	29.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3wig	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 (Homo sapiens)	8 / 12	LEU A  75 VAL A  83 ALA A  96 LYS A  98 MET A 147 GLY A 150 LEU A 198 ASP A 209	ANP  A 401 (-3.8A) ANP  A 401 ( 4.3A) ANP  A 401 (-3.2A) ANP  A 401 (-2.7A) None ANP  A 401 ( 4.3A) ANP  A 401 (-4.8A) MG  A 402 (-3.2A)	0.61A	26.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	6 / 12	LEU A1951 VAL A1959 ALA A1978 MET A2029 GLY A2032 LEU A2086	VGH  A3000 ( 4.4A) None VGH  A3000 (-3.4A) None VGH  A3000 (-3.5A) VGH  A3000 (-4.3A)	0.51A	35.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3zfx	EPHRIN TYPE-B RECEPTOR 1 (Homo sapiens)	7 / 12	ALA A 649 LYS A 651 THR A 697 MET A 700 GLY A 703 LEU A 751 ASP A 762	None	0.87A	36.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3zfx	EPHRIN TYPE-B RECEPTOR 1 (Homo sapiens)	7 / 12	VAL A 633 ALA A 649 LYS A 651 THR A 697 MET A 700 GLY A 703 LEU A 751	None	0.73A	36.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4af3	AURORA KINASE B (Homo sapiens)	6 / 12	LEU A  83 VAL A  91 ALA A 104 LYS A 106 GLY A 160 LEU A 207	VX6  A 500 (-3.8A) VX6  A 500 ( 4.8A) VX6  A 500 (-3.4A) VX6  A 500 (-3.3A) VX6  A 500 (-3.3A) VX6  A 500 (-4.6A)	0.48A	25.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4at3	BDNF/NT-3 GROWTH FACTORS RECEPTOR (Homo sapiens)	6 / 12	LEU A 560 VAL A 568 ALA A 586 MET A 636 GLY A 639 LEU A 699	LTI  A1839 ( 4.2A) None LTI  A1839 (-3.3A) None LTI  A1839 (-3.4A) LTI  A1839 (-4.2A)	0.53A	30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4aw5	EPHRIN TYPE-B RECEPTOR 4 (Homo sapiens)	7 / 12	VAL A 105 ALA A 121 LYS A 123 THR A 169 MET A 172 GLY A 175 LEU A 223	30K  A1365 ( 4.6A) 30K  A1365 (-3.2A) 30K  A1365 (-3.8A) 30K  A1365 (-3.8A) None 30K  A1365 (-3.5A) 30K  A1365 (-4.5A)	0.54A	32.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4c02	ACTIVIN RECEPTOR TYPE-1 (Homo sapiens)	7 / 12	VAL A 222 ALA A 233 LYS A 235 THR A 283 GLY A 289 LEU A 343 ASP A 354	TAK  A1507 (-4.7A) TAK  A1507 (-3.3A) TAK  A1507 ( 4.5A) TAK  A1507 (-3.6A) TAK  A1507 (-3.5A) TAK  A1507 (-4.7A) TAK  A1507 (-3.5A)	0.69A	24.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4f0i	HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR (Homo sapiens)	6 / 12	LEU A 515 VAL A 523 ALA A 541 MET A 591 GLY A 594 LEU A 656	None	0.43A	31.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4fl3	TYROSINE-PROTEIN KINASE SYK (Homo sapiens)	7 / 12	LEU A 377 VAL A 385 ALA A 400 LYS A 402 GLY A 454 LEU A 501 ASP A 512	ANP  A 701 ( 4.6A) ANP  A 701 (-4.1A) ANP  A 701 (-3.3A) ANP  A 701 (-2.7A) ANP  A 701 ( 4.2A) ANP  A 701 (-4.5A) MG  A 702 ( 3.1A)	0.56A	21.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	6 / 12	LEU A1122 VAL A1130 ALA A1148 MET A1199 GLY A1202 LEU A1256	0UV  A1501 (-3.8A) 0UV  A1501 (-4.5A) 0UV  A1501 (-3.4A) None 0UV  A1501 (-3.6A) 0UV  A1501 (-4.6A)	0.49A	31.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4gv1	RAC-ALPHA SERINE/THREONINE-PRO TEIN KINASE (Homo sapiens)	7 / 12	LEU A 156 VAL A 164 ALA A 177 LYS A 179 GLY A 233 THR A 291 ASP A 292	0XZ  A 501 ( 4.1A) 0XZ  A 501 (-4.5A) 0XZ  A 501 (-3.3A) GOL  A 503 ( 2.8A) None 0XZ  A 501 ( 4.1A) 0XZ  A 501 ( 3.4A)	0.97A	23.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4hzs	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	8 / 12	LEU A 132 VAL A 140 ALA A 156 LYS A 158 THR A 205 GLY A 211 LEU A 259 ASP A 270	None	0.70A	35.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4id7	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	7 / 12	LEU A 132 VAL A 140 ALA A 156 LYS A 158 THR A 205 GLY A 211 LEU A 259	1G0  A 401 ( 4.5A) 1G0  A 401 (-4.4A) 1G0  A 401 (-3.6A) 1G0  A 401 (-3.7A) 1G0  A 401 (-3.2A) 1G0  A 401 ( 4.5A) 1G0  A 401 (-4.6A)	0.81A	35.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4k11	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	8 / 12	LEU A 273 VAL A 281 ALA A 293 LYS A 295 MET A 341 GLY A 344 LEU A 393 ASP A 404	0J9  A 601 (-4.0A) 0J9  A 601 (-4.4A) 0J9  A 601 (-3.3A) 0J9  A 601 ( 4.7A) None 0J9  A 601 ( 4.1A) 0J9  A 601 (-4.5A) 0J9  A 601 (-3.1A)	0.55A	26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	7 / 12	LEU A  46 VAL A  54 ALA A  67 LYS A  69 THR A 123 GLY A 128 LEU A 180	SIN  A 401 ( 3.9A) None SIN  A 401 ( 3.7A) None None SIN  A 401 (-3.5A) SIN  A 401 ( 4.5A)	0.65A	21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4oli	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	6 / 12	LEU A 595 VAL A 603 LYS A 642 THR A 687 GLY A 693 LEU A 741	2TT  A1201 (-4.1A) 2TT  A1201 (-4.2A) 2TT  A1201 ( 4.6A) None 2TT  A1201 (-3.5A) 2TT  A1201 (-4.1A)	0.52A	20.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4p2k	EPHRIN TYPE-A RECEPTOR 2 (Homo sapiens)	6 / 12	VAL A 627 ALA A 644 THR A 692 MET A 695 GLY A 698 LEU A 746	None	0.47A	34.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4uy9	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9 (Homo sapiens)	7 / 12	VAL A 158 ALA A 169 LYS A 171 GLY A 226 LEU A 275 THR A 293 ASP A 294	None	1.26A	31.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	LEU B 267 VAL B 275 ALA B 288 LYS B 290 THR B 334 MET B 337 GLY B 340 LEU B 389	1N1  B 601 (-3.7A) 1N1  B 601 ( 4.9A) 1N1  B 601 (-3.5A) 1N1  B 601 (-4.6A) 1N1  B 601 (-3.3A) None 1N1  B 601 (-3.5A) 1N1  B 601 (-4.3A)	0.42A	28.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5a46	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens)	7 / 12	LEU A 484 VAL A 492 ALA A 512 LYS A 514 GLY A 567 LEU A 630 ASP A 641	38O  A1769 (-3.2A) 38O  A1769 (-4.5A) 38O  A1769 (-3.6A) 38O  A1769 ( 3.1A) 38O  A1769 (-3.4A) 38O  A1769 (-4.6A) 38O  A1769 (-4.0A)	0.89A	32.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	7 / 12	LEU A 599 VAL A 607 ALA A 625 LYS A 627 THR A 674 GLY A 680 LEU A 825	748  A1001 (-3.8A) 748  A1001 ( 4.7A) 748  A1001 (-3.7A) 748  A1001 (-4.0A) 748  A1001 (-3.2A) 748  A1001 ( 4.0A) 748  A1001 (-4.3A)	0.64A	31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5j9z	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	8 / 12	LEU A 718 ALA A 743 MET A 793 GLY A 796 CYH A 797 LEU A 844 THR A 854 ASP A 855	6HJ  A1101 ( 4.6A) 6HJ  A1101 (-3.1A) None 6HJ  A1101 ( 4.5A) 6HJ  A1101 (-1.6A) 6HJ  A1101 ( 4.8A) 6HJ  A1101 (-3.9A) 6HJ  A1101 (-4.3A)	0.90A	99.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5j9z	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	7 / 12	LEU A 718 VAL A 726 ALA A 743 LYS A 745 MET A 793 GLY A 796 LEU A 844	6HJ  A1101 ( 4.6A) 6HJ  A1101 ( 4.7A) 6HJ  A1101 (-3.1A) 6HJ  A1101 (-4.2A) None 6HJ  A1101 ( 4.5A) 6HJ  A1101 ( 4.8A)	0.67A	99.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5j9z	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	8 / 12	LEU A 718 VAL A 726 ALA A 743 MET A 793 GLY A 796 CYH A 797 LEU A 844 THR A 854	6HJ  A1101 ( 4.6A) 6HJ  A1101 ( 4.7A) 6HJ  A1101 (-3.1A) None 6HJ  A1101 ( 4.5A) 6HJ  A1101 (-1.6A) 6HJ  A1101 ( 4.8A) 6HJ  A1101 (-3.9A)	0.82A	99.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5kbr	SERINE/THREONINE-PRO TEIN KINASE PAK 1 (Homo sapiens)	6 / 12	VAL A 284 ALA A 297 LYS A 299 GLY A 350 LEU A 396 THR A 406	IPW  A 601 (-4.2A) IPW  A 601 (-3.5A) IPW  A 601 (-4.5A) IPW  A 601 ( 3.8A) IPW  A 601 (-4.5A) IPW  A 601 (-3.7A)	0.55A	26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5vil	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (Homo sapiens)	7 / 12	LEU A 686 VAL A 694 ALA A 707 LYS A 709 GLY A 760 LEU A 810 ASP A 822	9E1  A1001 (-3.7A) 9E1  A1001 ( 4.0A) 9E1  A1001 (-3.5A) 9E1  A1001 (-2.8A) 9E1  A1001 (-3.4A) 9E1  A1001 (-4.5A) 9E1  A1001 (-3.6A)	1.08A	11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	5w5j	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2 (Homo sapiens)	8 / 12	LEU A  24 VAL A  32 ALA A  45 LYS A  47 THR A  95 MET A  98 GLY A 101 LEU A 153	9WS  A 401 ( 4.2A) 9WS  A 401 ( 4.6A) 9WS  A 401 (-3.3A) 9WS  A 401 (-3.3A) 9WS  A 401 (-3.2A) None 9WS  A 401 ( 4.3A) 9WS  A 401 (-4.6A)	0.58A	27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	6ao5	SERINE/THREONINE-PRO TEIN KINASE 3 (Homo sapiens)	7 / 12	LEU A  33 VAL A  41 ALA A  54 LYS A  56 GLY A 105 LEU A 153 ASP A 164	ANP  A 501 ( 3.8A) ANP  A 501 (-4.4A) ANP  A 501 ( 3.7A) ANP  A 501 (-2.4A) ANP  A 501 ( 4.0A) ANP  A 501 (-4.6A) MG  A 502 ( 3.1A)	0.57A	27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	6cz4	PROTEIN-TYROSINE KINASE 6 (Homo sapiens)	8 / 12	LEU A 197 VAL A 205 ALA A 217 LYS A 219 THR A 264 MET A 267 GLY A 270 LEU A 319	FKY  A9001 (-4.1A) FKY  A9001 ( 4.6A) FKY  A9001 (-3.3A) None FKY  A9001 (-3.0A) None FKY  A9001 (-3.3A) FKY  A9001 ( 4.9A)	0.84A	16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	1wao	SERINE/THREONINE PROTEIN PHOSPHATASE 5 (Homo sapiens)	5 / 12	SER 1 403 ASN 1 269 LEU 1 300 ASP 1 383 GLY 1 354	None	1.17A	10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	1z8l	GLUTAMATE CARBOXYPEPTIDASE II (Homo sapiens)	5 / 12	SER A 431 ASN A 260 ASN A 257 ASP A 520 GLY A 518	None	1.20A	8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	2d99	GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 12	SER A  73 PHE A  78 LEU A  80 ASP A  17 ILE A  69	None	1.37A	22.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	2hi4	CYTOCHROME P450 1A2 (Homo sapiens)	6 / 12	PHE A 226 ASN A 257 ASP A 313 GLY A 316 ASP A 320 ILE A 386	BHF  A 800 (-3.6A) None BHF  A 800 (-3.9A) BHF  A 800 (-3.8A) BHF  A 800 (-4.0A) HEM  A 900 (-4.0A)	0.55A	81.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	2izv	SUPPRESSOR OF CYTOKINE SIGNALING 4 (Homo sapiens)	5 / 12	SER A 323 ASN A 282 LEU A 278 GLY A 289 PHE A 387	None None None CL  A1432 ( 4.0A) CL  A1432 ( 4.6A)	1.35A	19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	2v9t	ROUNDABOUT HOMOLOG 1 SLIT HOMOLOG 2 PROTEIN N-PRODUCT (Homo sapiens; Homo sapiens)	5 / 12	SER A  75 ASN B 334 ASN B 358 LEU B 331 GLY B 288	None	1.30A	21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	3fed	GLUTAMATE CARBOXYPEPTIDASE III (Homo sapiens)	5 / 12	SER A 421 ASN A 250 ASN A 247 ASP A 510 GLY A 508	None None BIX  A   1 (-3.2A) None BIX  A   1 (-3.4A)	1.17A	9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	3h68	SERINE/THREONINE-PRO TEIN PHOSPHATASE 5 (Homo sapiens)	5 / 12	SER A 403 ASN A 269 LEU A 300 ASP A 383 GLY A 354	None	1.22A	14.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	3pm0	CYTOCHROME P450 1B1 (Homo sapiens)	5 / 12	ASN A 228 PHE A 231 PHE A 268 ASP A 326 GLY A 329	BHF  A 800 (-4.2A) BHF  A 800 (-3.4A) BHF  A 800 ( 3.8A) BHF  A 800 (-3.4A) BHF  A 800 ( 4.0A)	1.19A	58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	3pm0	CYTOCHROME P450 1B1 (Homo sapiens)	7 / 12	PHE A 231 ASN A 265 PHE A 268 ASP A 326 GLY A 329 ASP A 333 ILE A 399	BHF  A 800 (-3.4A) None BHF  A 800 ( 3.8A) BHF  A 800 (-3.4A) BHF  A 800 ( 4.0A) BHF  A 800 ( 4.1A) HEM  A 900 (-4.0A)	0.62A	58.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	3rw7	NUCLEAR RNA EXPORT FACTOR 1 (Homo sapiens)	5 / 12	ASN A 301 ASN A 325 LEU A 298 ASN A 297 GLY A 231	None	1.24A	15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	3zyj	LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C (Homo sapiens)	5 / 12	ASN A 277 ASN A 301 LEU A 274 ASN A 273 GLY A 228	None	1.18A	8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	3zyj	LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C NETRIN-G1 (Homo sapiens; Homo sapiens)	5 / 12	SER B 228 ASN A 277 ASN A 301 LEU A 274 GLY A 228	None	1.24A	14.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	5 / 12	ASN A 222 ASN A 223 LEU A 254 PHE A 258 PHE A 319	BHF  A 602 ( 3.8A) None None BHF  A 602 ( 3.9A) BHF  A 602 ( 4.7A)	1.17A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	5 / 12	ASN A 223 LEU A 254 ASN A 255 PHE A 258 PHE A 319	None None None BHF  A 602 ( 3.9A) BHF  A 602 ( 4.7A)	1.01A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	6 / 12	SER A 120 ASN A 222 PHE A 224 ASP A 313 GLY A 316 PHE A 319	BHF  A 602 ( 4.5A) BHF  A 602 ( 3.8A) BHF  A 602 (-3.3A) BHF  A 602 (-3.7A) BHF  A 602 (-3.5A) BHF  A 602 ( 4.7A)	1.49A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	6 / 12	SER A 120 PHE A 224 ASP A 313 GLY A 316 PHE A 319 ASP A 320	BHF  A 602 ( 4.5A) BHF  A 602 (-3.3A) BHF  A 602 (-3.7A) BHF  A 602 (-3.5A) BHF  A 602 ( 4.7A) BHF  A 602 (-3.7A)	1.48A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	9 / 12	SER A 122 ASN A 222 ASN A 223 PHE A 224 PHE A 258 ASP A 313 GLY A 316 PHE A 319 ILE A 386	HEM  A 601 (-3.4A) BHF  A 602 ( 3.8A) None BHF  A 602 (-3.3A) BHF  A 602 ( 3.9A) BHF  A 602 (-3.7A) BHF  A 602 (-3.5A) BHF  A 602 ( 4.7A) HEM  A 601 (-3.6A)	0.69A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	10 / 12	SER A 122 ASN A 223 PHE A 224 ASN A 255 PHE A 258 ASP A 313 GLY A 316 PHE A 319 ASP A 320 ILE A 386	HEM  A 601 (-3.4A) None BHF  A 602 (-3.3A) None BHF  A 602 ( 3.9A) BHF  A 602 (-3.7A) BHF  A 602 (-3.5A) BHF  A 602 ( 4.7A) BHF  A 602 (-3.7A) HEM  A 601 (-3.6A)	0.48A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	4ztd	PROLIFERATING CELL NUCLEAR ANTIGEN (Homo sapiens)	5 / 12	ASN A  36 LEU A  50 ASP A 243 GLY A  56 PHE A  57	None	1.37A	15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	5grh	ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT GAMMA, MITOCHONDRIAL (Homo sapiens)	5 / 12	ASN B  94 ASN B  93 ASN B 239 GLY B 133 ILE B 161	None	1.33A	12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	5lsk	KINETOCHORE-ASSOCIAT ED PROTEIN DSN1 HOMOLOG KINETOCHORE-ASSOCIAT ED PROTEIN NSL1 HOMOLOG (Homo sapiens; Homo sapiens)	5 / 12	LEU N  52 PHE D 178 ASP D 180 GLY D 181 ASP D 185	None	1.27A	14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	1bf5	SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA (Homo sapiens)	4 / 5	ILE A 647 SER A 708 ALA A 611 LEU A 569	None	0.92A	7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	1bix	AP ENDONUCLEASE 1 (Homo sapiens)	4 / 5	ILE A  91 SER A 135 LEU A 316 LYS A  58	None	0.99A	15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	1zrz	PROTEIN KINASE C, IOTA (Homo sapiens)	4 / 5	ILE A 353 SER A 354 ALA A 346 LEU A 331	None	1.06A	14.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	2hi4	CYTOCHROME P450 1A2 (Homo sapiens)	4 / 5	ILE A 117 ALA A 317 LEU A 497 LYS A 500	None HEM  A 900 ( 3.5A) BHF  A 800 (-4.4A) None	0.42A	81.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	2rex	RHO-RELATED GTP-BINDING PROTEIN RHO6 (Homo sapiens)	4 / 5	ILE B 147 SER B 148 ALA B 156 LEU B 104	None None UNX  B 559 ( 4.1A) None	1.02A	14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	3g4g	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	4 / 5	ILE A 291 ALA A 332 LEU A 270 LYS A 490	None	0.99A	13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	3hf1	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE SUBUNIT M2 B (Homo sapiens)	4 / 5	ILE A 224 SER A 220 ALA A  97 LYS A 168	None	0.95A	14.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	3pm0	CYTOCHROME P450 1B1 (Homo sapiens)	4 / 5	SER A 127 ALA A 330 LEU A 509 LYS A 512	BHF  A 800 ( 4.6A) HEM  A 900 ( 3.4A) BHF  A 800 (-4.7A) None	0.77A	58.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	4cak	INTEGRIN ALPHA-IIB (Homo sapiens)	4 / 5	ILE A 701 SER A 344 ALA A 650 LEU A 614	None	1.03A	6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	4 / 5	ILE A 738 SER A 739 ALA A 747 LEU A 709	None	1.07A	15.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	5 / 5	ILE A 115 SER A 116 ALA A 317 LEU A 496 LYS A 499	BHF  A 602 (-4.7A) BHF  A 602 (-3.2A) BHF  A 602 ( 3.4A) None None	0.43A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	4n49	CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1 (Homo sapiens)	4 / 5	ILE A 342 SER A 343 ALA A 462 LEU A 385	None	0.93A	15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	4xwx	SHC-TRANSFORMING PROTEIN 1 (Homo sapiens)	4 / 5	ILE A 150 SER A 149 ALA A 143 LEU A 124	None	1.06A	18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	5cek	TRIBBLES HOMOLOG 1 (Homo sapiens)	4 / 5	ILE A 307 SER A 308 ALA A 183 LEU A 277	None	0.94A	13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	5dot	CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL (Homo sapiens)	4 / 5	ILE A1192 SER A1193 ALA A1180 LEU A1296	None	0.98A	4.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	5ikr	PROSTAGLANDIN G/H SYNTHASE 2 (Homo sapiens)	4 / 5	ILE A 452 SER A 455 ALA A 506 LEU A 181	None	0.97A	10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	5uvg	SPHINGOMYELIN PHOSPHODIESTERASE 3,SPHINGOMYELIN PHOSPHODIESTERASE 3 (Homo sapiens)	4 / 5	ILE A 630 SER A 350 ALA A 162 LEU A 360	None	0.91A	11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	5wh6	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	4 / 5	ILE A 125 ALA A 166 LEU A 104 LYS A 324	None	0.96A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	6d9h	CHIMERA PROTEIN OF MUSCARINIC ACETYLCHOLINE RECEPTOR M4 AND ADENOSINE RECEPTOR A1 (Homo sapiens)	4 / 5	ILE R 239 SER R 235 ALA R 289 LEU R  51	None	1.07A	21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	1lw3	MYOTUBULARIN-RELATED PROTEIN 2 (Homo sapiens)	5 / 12	ILE A 544 SER A 539 LEU A 505 PHE A 445 PHE A 480	None	1.43A	9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	1zsq	MYOTUBULARIN-RELATED PROTEIN 2 (Homo sapiens)	5 / 12	ILE A 544 SER A 539 LEU A 505 PHE A 445 PHE A 480	None	1.42A	10.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	2hi4	CYTOCHROME P450 1A2 (Homo sapiens)	7 / 12	ILE A 117 PHE A 226 ASN A 257 ASP A 313 ASP A 320 ILE A 386 LYS A 500	None BHF  A 800 (-3.6A) None BHF  A 800 (-3.9A) BHF  A 800 (-4.0A) HEM  A 900 (-4.0A) None	0.65A	81.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	2hi4	CYTOCHROME P450 1A2 (Homo sapiens)	6 / 12	ILE A 117 PHE A 226 ASN A 257 PHE A 260 ASP A 320 LYS A 500	None BHF  A 800 (-3.6A) None BHF  A 800 (-3.6A) BHF  A 800 (-4.0A) None	0.92A	81.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	2hi4	CYTOCHROME P450 1A2 (Homo sapiens)	5 / 12	PHE A 226 LEU A 219 ASP A 313 ILE A 386 LYS A 500	BHF  A 800 (-3.6A) None BHF  A 800 (-3.9A) HEM  A 900 (-4.0A) None	1.44A	81.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	2jdx	PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE) (Homo sapiens)	5 / 12	ASN A 361 PHE A 405 LEU A 358 ASN A 399 ILE A 133	None	1.48A	11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	2odp	COMPLEMENT C2 (Homo sapiens)	5 / 12	SER A 256 LEU A 406 PHE A 278 ASP A 240 ILE A 252	None None None MG  A 901 ( 3.9A) None	1.49A	10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	2z63	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	LEU A 532 ASN A 530 ASP A 502 PHE A 516 ILE A 454	None	1.25A	9.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	3pm0	CYTOCHROME P450 1B1 (Homo sapiens)	7 / 12	PHE A 231 ASN A 265 PHE A 268 ASP A 326 ASP A 333 ILE A 399 LYS A 512	BHF  A 800 (-3.4A) None BHF  A 800 ( 3.8A) BHF  A 800 (-3.4A) BHF  A 800 ( 4.1A) HEM  A 900 (-4.0A) None	0.81A	58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	3pm0	CYTOCHROME P450 1B1 (Homo sapiens)	5 / 12	SER A 131 LEU A 224 ASP A 326 ASP A 333 LYS A 512	BHF  A 800 ( 4.7A) None BHF  A 800 (-3.4A) BHF  A 800 ( 4.1A) None	1.43A	58.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	4crs	SERINE/THREONINE-PRO TEIN KINASE N2 (Homo sapiens)	5 / 12	ILE A 685 LEU A 723 PHE A 735 PHE A 977 ASP A 978	None	1.45A	11.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	5 / 12	ILE A 115 ASN A 223 PHE A 224 ASN A 255 ILE A 386	BHF  A 602 (-4.7A) None BHF  A 602 (-3.3A) None HEM  A 601 (-3.6A)	1.34A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	8 / 12	ILE A 115 SER A 122 ASN A 222 LEU A 254 ASN A 255 PHE A 258 ASP A 313 PHE A 319	BHF  A 602 (-4.7A) HEM  A 601 (-3.4A) BHF  A 602 ( 3.8A) None None BHF  A 602 ( 3.9A) BHF  A 602 (-3.7A) BHF  A 602 ( 4.7A)	0.90A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	9 / 12	ILE A 115 SER A 122 ASN A 222 PHE A 224 ASN A 255 PHE A 258 ASP A 313 PHE A 319 ILE A 386	BHF  A 602 (-4.7A) HEM  A 601 (-3.4A) BHF  A 602 ( 3.8A) BHF  A 602 (-3.3A) None BHF  A 602 ( 3.9A) BHF  A 602 (-3.7A) BHF  A 602 ( 4.7A) HEM  A 601 (-3.6A)	0.75A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	9 / 12	ILE A 115 SER A 122 PHE A 224 ASN A 255 ASP A 313 PHE A 319 ASP A 320 ILE A 386 LYS A 499	BHF  A 602 (-4.7A) HEM  A 601 (-3.4A) BHF  A 602 (-3.3A) None BHF  A 602 (-3.7A) BHF  A 602 ( 4.7A) BHF  A 602 (-3.7A) HEM  A 601 (-3.6A) None	0.44A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	9 / 12	ILE A 115 SER A 122 PHE A 224 ASN A 255 PHE A 258 ASP A 313 PHE A 319 ASP A 320 ILE A 386	BHF  A 602 (-4.7A) HEM  A 601 (-3.4A) BHF  A 602 (-3.3A) None BHF  A 602 ( 3.9A) BHF  A 602 (-3.7A) BHF  A 602 ( 4.7A) BHF  A 602 (-3.7A) HEM  A 601 (-3.6A)	0.57A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	5 / 12	SER A 122 LEU A 217 ASP A 313 ASP A 320 LYS A 499	HEM  A 601 (-3.4A) None BHF  A 602 (-3.7A) BHF  A 602 (-3.7A) None	1.35A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	5 / 12	SER A 122 PHE A 315 ASP A 313 ASP A 320 LYS A 499	HEM  A 601 (-3.4A) None BHF  A 602 (-3.7A) BHF  A 602 (-3.7A) None	1.44A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	4igg	CATENIN ALPHA-1 (Homo sapiens)	5 / 12	LEU A 364 ASN A 365 PHE A 301 ASP A 292 ILE A 792	None	1.45A	6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	4kjy	LEUKOCYTE SURFACE ANTIGEN CD47 HIGH-AFFINITY SIRPA VARIANT FD6 (Homo sapiens; Homo sapiens)	5 / 12	ILE B  36 LEU B  48 PHE B  39 ASP B 100 LYS A  39	None	1.32A	18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	4kt1	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4 (Homo sapiens)	5 / 12	SER A 371 LEU A 425 ASN A 423 ASP A 395 PHE A 409	None	1.38A	9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	5c16	MYOTUBULARIN-RELATED PROTEIN 1 (Homo sapiens)	5 / 12	ILE A 565 SER A 560 LEU A 526 PHE A 466 PHE A 501	None	1.44A	9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	5edv	E3 UBIQUITIN-PROTEIN LIGASE RNF31 (Homo sapiens)	5 / 12	ILE A 739 PHE A 762 LEU A 769 PHE A 730 ASP A 741	None	1.40A	11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	5lkz	HISTONE ACETYLTRANSFERASE P300,HISTONE ACETYLTRANSFERASE P300 (Homo sapiens)	5 / 12	ILE A1417 PHE A1374 PHE A1448 ASP A1399 ILE A1395	None None None COO  A1705 (-4.2A) None	1.40A	8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_0 (CYTOCHROME P450 1A1)	6c9m	N-ALPHA-ACETYLTRANSF ERASE 15, NATA AUXILIARY SUBUNIT N-ALPHA-ACETYLTRANSF ERASE 10 (Homo sapiens; Homo sapiens)	5 / 12	SER A 121 PHE A 523 ASP A 524 ILE A 125 LYS B  29	None	1.39A	25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	1ih5	AQUAPORIN-1 (Homo sapiens)	4 / 7	ASN A  76 GLY A 219 ALA A 221 LEU A  81	None	0.77A	16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	1u59	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	4 / 7	PHE A 586 ALA A 464 VAL A 438 LEU A 442	None	0.73A	14.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	2hi4	CYTOCHROME P450 1A2 (Homo sapiens)	4 / 7	PHE A 253 GLY A 316 ALA A 317 LEU A 497	None BHF  A 800 (-3.8A) HEM  A 900 ( 3.5A) BHF  A 800 (-4.4A)	0.35A	81.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	2hlw	UBIQUITIN-CONJUGATIN G ENZYME E2 VARIANT 1 (Homo sapiens)	4 / 7	ASN A 114 GLY A 121 VAL A 143 LEU A 147	None	0.84A	17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	2m8h	RNA-BINDING PROTEIN 7 (Homo sapiens)	4 / 7	GLY A  41 ALA A  40 VAL A  21 LEU A  19	None	0.79A	17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	2ozo	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	4 / 7	PHE A 586 ALA A 464 VAL A 438 LEU A 442	None	0.70A	8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	3j7y	MS30 (Homo sapiens)	5 / 7	ASN s 280 GLY s 337 ALA s 340 VAL s  76 LEU s  80	None	1.48A	12.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	3pm0	CYTOCHROME P450 1B1 (Homo sapiens)	6 / 7	SER A 127 PHE A 261 GLY A 329 ALA A 330 VAL A 395 LEU A 509	BHF  A 800 ( 4.6A) None BHF  A 800 ( 4.0A) HEM  A 900 ( 3.4A) HEM  A 900 (-4.6A) BHF  A 800 (-4.7A)	0.55A	58.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	3qpq	C1068 HEAVY CHAIN (Homo sapiens; Mus musculus)	4 / 7	GLY H   8 ALA H   9 VAL H  18 LEU H  20	None	0.80A	16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	4akv	SORTING NEXIN-33 (Homo sapiens)	4 / 7	ASN A 481 GLY A 355 ALA A 356 LEU A 488	None	0.80A	12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	4b8w	GDP-L-FUCOSE SYNTHASE (Homo sapiens)	4 / 7	ASN A  96 GLY A  14 VAL A  61 LEU A  57	None NAP  A 900 (-3.0A) None None	0.74A	14.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	7 / 7	SER A 116 ASN A 223 PHE A 251 GLY A 316 ALA A 317 VAL A 382 LEU A 496	BHF  A 602 (-3.2A) None None BHF  A 602 (-3.5A) BHF  A 602 ( 3.4A) HEM  A 601 (-4.9A) None	0.38A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	5nqa	POLYPEPTIDE N-ACETYLGALACTOSAMIN YLTRANSFERASE 4 (Homo sapiens)	4 / 7	ASN A 378 GLY A 311 VAL A 345 LEU A 341	None EDO  A 601 ( 3.8A) None None	0.69A	20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	5nqa	POLYPEPTIDE N-ACETYLGALACTOSAMIN YLTRANSFERASE 4 (Homo sapiens)	4 / 7	ASN A 378 GLY A 312 VAL A 345 LEU A 341	None EDO  A 612 ( 3.2A) None None	0.73A	20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	1nst	HEPARAN SULFATE N-DEACETYLASE/N-SULF OTRANSFERASE (Homo sapiens)	5 / 12	LEU A 859 ASN A 856 ASP A 708 ILE A 734 LEU A 752	None	0.99A	14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	2hgs	PROTEIN (GLUTATHIONE SYNTHETASE) (Homo sapiens)	5 / 12	ILE A 235 ASP A 257 GLY A 258 ILE A 242 LEU A 254	None	1.05A	10.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	2hi4	CYTOCHROME P450 1A2 (Homo sapiens)	7 / 12	ILE A 117 PHE A 226 ASN A 257 ASP A 313 GLY A 316 ILE A 386 LEU A 497	None BHF  A 800 (-3.6A) None BHF  A 800 (-3.9A) BHF  A 800 (-3.8A) HEM  A 900 (-4.0A) BHF  A 800 (-4.4A)	0.64A	81.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	2hi4	CYTOCHROME P450 1A2 (Homo sapiens)	5 / 12	ILE A 117 PHE A 226 ASN A 257 PHE A 260 LEU A 497	None BHF  A 800 (-3.6A) None BHF  A 800 (-3.6A) BHF  A 800 (-4.4A)	0.89A	81.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	3e73	LANC-LIKE PROTEIN 1 (Homo sapiens)	5 / 12	ILE A 182 LEU A 140 ASN A 141 GLY A 157 LEU A 163	None	1.06A	12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	3eh1	PROTEIN TRANSPORT PROTEIN SEC24B (Homo sapiens)	5 / 12	ILE A1124 PHE A1179 GLY A1157 ILE A1229 LEU A1184	None	1.00A	8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	3fn1	NEDD8-CONJUGATING ENZYME UBE2F (Homo sapiens)	5 / 12	ILE B 104 PHE B 172 PHE B 153 ILE B 115 LEU B 146	None	1.13A	18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	3h11	CASP8 AND FADD-LIKE APOPTOSIS REGULATOR (Homo sapiens)	5 / 12	ILE A 289 SER A 314 GLY A 330 ILE A 357 LEU A 333	None	1.06A	18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	3h68	SERINE/THREONINE-PRO TEIN PHOSPHATASE 5 (Homo sapiens)	5 / 12	SER A 403 ASN A 269 LEU A 300 ASP A 383 GLY A 354	None	1.15A	14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	3mwe	ATP-CITRATE SYNTHASE (Homo sapiens)	5 / 12	ILE A 357 LEU A 388 GLY A 341 ILE A 323 LEU A 338	None	1.13A	11.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	3pm0	CYTOCHROME P450 1B1 (Homo sapiens)	6 / 12	ASN A 228 PHE A 231 PHE A 268 ASP A 326 GLY A 329 LEU A 509	BHF  A 800 (-4.2A) BHF  A 800 (-3.4A) BHF  A 800 ( 3.8A) BHF  A 800 (-3.4A) BHF  A 800 ( 4.0A) BHF  A 800 (-4.7A)	1.11A	58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	3pm0	CYTOCHROME P450 1B1 (Homo sapiens)	7 / 12	PHE A 231 ASN A 265 PHE A 268 ASP A 326 GLY A 329 ILE A 399 LEU A 509	BHF  A 800 (-3.4A) None BHF  A 800 ( 3.8A) BHF  A 800 (-3.4A) BHF  A 800 ( 4.0A) HEM  A 900 (-4.0A) BHF  A 800 (-4.7A)	0.65A	58.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	4bgq	CYCLIN-DEPENDENT KINASE-LIKE 5 (Homo sapiens)	5 / 12	ILE A 123 SER A 196 LEU A  67 ILE A 200 LEU A 141	None	1.11A	13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	4cak	INTEGRIN BETA-3 (Homo sapiens)	5 / 12	ASP B 259 GLY B 222 PHE B 156 ILE B 325 LEU B 306	None	1.14A	9.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	7 / 12	ASN A 222 LEU A 254 ASN A 255 PHE A 258 ASP A 313 GLY A 316 PHE A 319	BHF  A 602 ( 3.8A) None None BHF  A 602 ( 3.9A) BHF  A 602 (-3.7A) BHF  A 602 (-3.5A) BHF  A 602 ( 4.7A)	0.95A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	6 / 12	ILE A 115 ASN A 223 PHE A 224 ASN A 255 ILE A 386 LEU A 496	BHF  A 602 (-4.7A) None BHF  A 602 (-3.3A) None HEM  A 601 (-3.6A) None	1.44A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	11 / 12	ILE A 115 SER A 122 ASN A 222 PHE A 224 ASN A 255 PHE A 258 ASP A 313 GLY A 316 PHE A 319 ILE A 386 LEU A 496	BHF  A 602 (-4.7A) HEM  A 601 (-3.4A) BHF  A 602 ( 3.8A) BHF  A 602 (-3.3A) None BHF  A 602 ( 3.9A) BHF  A 602 (-3.7A) BHF  A 602 (-3.5A) BHF  A 602 ( 4.7A) HEM  A 601 (-3.6A) None	0.63A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	6 / 12	SER A 120 ASN A 222 PHE A 224 ASP A 313 GLY A 316 PHE A 319	BHF  A 602 ( 4.5A) BHF  A 602 ( 3.8A) BHF  A 602 (-3.3A) BHF  A 602 (-3.7A) BHF  A 602 (-3.5A) BHF  A 602 ( 4.7A)	1.44A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	4kt1	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4 (Homo sapiens)	5 / 12	LEU A 425 ASN A 423 ASP A 395 PHE A 409 LEU A 358	None	1.08A	9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	4u1r	ATP-DEPENDENT 6-PHOSPHOFRUCTOKINAS E, PLATELET TYPE (Homo sapiens)	5 / 12	ILE A 491 LEU A 483 GLY A 449 ILE A 500 LEU A 503	None	1.04A	7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_0 (CYTOCHROME P450 1A1)	5hmp	UNCONVENTIONAL MYOSIN-VC (Homo sapiens)	5 / 12	ILE A 158 GLY A 432 PHE A 430 ILE A 436 LEU A 635	None	0.97A	7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_1 (CYTOCHROME P450 1A1)	1kfu	M-CALPAIN LARGE SUBUNIT (Homo sapiens)	3 / 3	SER L 241 SER L 336 ALA L 199	None	0.48A	8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_1 (CYTOCHROME P450 1A1)	1l1o	REPLICATION PROTEIN A 32 KDA SUBUNIT REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT (Homo sapiens; Homo sapiens)	3 / 3	SER C 613 SER C 609 ALA B 165	None	0.71A	15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_1 (CYTOCHROME P450 1A1)	2a9m	FLUORESCEIN-SCFV HEAVY CHAIN (Homo sapiens)	3 / 3	SER H 113 SER H 134 ALA H 107	None	0.52A	21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_1 (CYTOCHROME P450 1A1)	2a9m	FLUORESCEIN-SCFV HEAVY CHAIN (Homo sapiens)	3 / 3	SER H 114 SER H 113 ALA H 107	None	0.69A	21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_1 (CYTOCHROME P450 1A1)	2j1l	RHO-RELATED GTP-BINDING PROTEIN RHOD (Homo sapiens)	3 / 3	SER A 193 SER A 192 ALA A 167	None	0.72A	16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_1 (CYTOCHROME P450 1A1)	2vx2	ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3 (Homo sapiens)	3 / 3	SER A 167 SER A 170 ALA A  98	None	0.69A	16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_1 (CYTOCHROME P450 1A1)	2xzo	REGULATOR OF NONSENSE TRANSCRIPTS 1 (Homo sapiens)	3 / 3	SER A 812 SER A 810 ALA A 770	MG  A1007 (-3.0A) MG  A1007 (-3.9A) None	0.59A	9.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_C_AQ4C602_1 (CYTOCHROME P450 1A1)	3pm0	CYTOCHROME P450 1B1 (Homo sapiens)	3 / 3	SER A 127 SER A 131 ALA A 330	BHF  A 800 ( 4.6A) BHF  A 800 ( 4.7A) HEM  A 900 ( 3.4A)	0.62A	58.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_1 (CYTOCHROME P450 1A1)	4bla	MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG (Escherichia coli; Homo sapiens)	3 / 3	SER A 454 SER A 436 ALA A 371	None	0.60A	8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_C_AQ4C602_1 (CYTOCHROME P450 1A1)	4fys	AMINOPEPTIDASE N (Homo sapiens)	3 / 3	SER A 373 SER A 374 ALA A 308	None	0.62A	6.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_C_AQ4C602_1 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	3 / 3	SER A 116 SER A 120 ALA A 317	BHF  A 602 (-3.2A) BHF  A 602 ( 4.5A) BHF  A 602 ( 3.4A)	0.30A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	2d92	INAD-LIKE PROTEIN (Homo sapiens)	5 / 12	ILE A  32 GLY A  29 ALA A  57 ILE A 101 LEU A  99	None	0.94A	20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	2hgs	PROTEIN (GLUTATHIONE SYNTHETASE) (Homo sapiens)	5 / 12	ILE A 235 ASP A 257 GLY A 258 ILE A 242 LEU A 254	None	1.06A	10.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	2hi4	CYTOCHROME P450 1A2 (Homo sapiens)	8 / 12	ILE A 117 PHE A 226 ASP A 313 GLY A 316 ALA A 317 ASP A 320 ILE A 386 LEU A 497	None BHF  A 800 (-3.6A) BHF  A 800 (-3.9A) BHF  A 800 (-3.8A) HEM  A 900 ( 3.5A) BHF  A 800 (-4.0A) HEM  A 900 (-4.0A) BHF  A 800 (-4.4A)	0.48A	81.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	2hi4	CYTOCHROME P450 1A2 (Homo sapiens)	5 / 12	ILE A 117 PHE A 226 PHE A 260 ASP A 320 LEU A 497	None BHF  A 800 (-3.6A) BHF  A 800 (-3.6A) BHF  A 800 (-4.0A) BHF  A 800 (-4.4A)	1.01A	81.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	3ber	PROBABLE ATP-DEPENDENT RNA HELICASE DDX47 (Homo sapiens)	5 / 12	PHE A  26 GLY A  76 ALA A  77 ILE A  52 LEU A  29	AMP  A 300 (-4.9A) None None None None	0.90A	18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	3eh1	PROTEIN TRANSPORT PROTEIN SEC24B (Homo sapiens)	5 / 12	ILE A1124 PHE A1179 GLY A1157 ILE A1229 LEU A1184	None	1.08A	8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	3eh1	PROTEIN TRANSPORT PROTEIN SEC24B (Homo sapiens)	5 / 12	ILE A1169 PHE A1179 GLY A1157 ASP A1176 ILE A1192	None	0.91A	8.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	3pm0	CYTOCHROME P450 1B1 (Homo sapiens)	6 / 12	ASN A 228 PHE A 231 PHE A 268 ASP A 326 GLY A 329 LEU A 509	BHF  A 800 (-4.2A) BHF  A 800 (-3.4A) BHF  A 800 ( 3.8A) BHF  A 800 (-3.4A) BHF  A 800 ( 4.0A) BHF  A 800 (-4.7A)	1.26A	58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	3pm0	CYTOCHROME P450 1B1 (Homo sapiens)	8 / 12	PHE A 231 PHE A 268 ASP A 326 GLY A 329 ALA A 330 ASP A 333 ILE A 399 LEU A 509	BHF  A 800 (-3.4A) BHF  A 800 ( 3.8A) BHF  A 800 (-3.4A) BHF  A 800 ( 4.0A) HEM  A 900 ( 3.4A) BHF  A 800 ( 4.1A) HEM  A 900 (-4.0A) BHF  A 800 (-4.7A)	0.71A	58.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	3wsy	SORTILIN-RELATED RECEPTOR (Homo sapiens)	5 / 12	ASN A 674 ASP A 357 GLY A 733 ASP A 734 LEU A 644	NAG  A 805 (-1.7A) None None None None	1.06A	8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	4duu	PLASMINOGEN (Homo sapiens)	5 / 12	SER A 203 PHE A 227 GLY A 199 ALA A 675 ASP A 676	None	0.97A	8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	4fzv	PUTATIVE METHYLTRANSFERASE NSUN4 (Homo sapiens)	5 / 12	SER A 162 PHE A  98 ASP A 159 GLY A  74 PHE A 142	None	1.04A	13.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	11 / 12	ILE A 115 SER A 122 ASN A 222 PHE A 224 PHE A 258 ASP A 313 GLY A 316 ALA A 317 PHE A 319 ILE A 386 LEU A 496	BHF  A 602 (-4.7A) HEM  A 601 (-3.4A) BHF  A 602 ( 3.8A) BHF  A 602 (-3.3A) BHF  A 602 ( 3.9A) BHF  A 602 (-3.7A) BHF  A 602 (-3.5A) BHF  A 602 ( 3.4A) BHF  A 602 ( 4.7A) HEM  A 601 (-3.6A) None	0.78A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	11 / 12	ILE A 115 SER A 122 PHE A 224 PHE A 258 ASP A 313 GLY A 316 ALA A 317 PHE A 319 ASP A 320 ILE A 386 LEU A 496	BHF  A 602 (-4.7A) HEM  A 601 (-3.4A) BHF  A 602 (-3.3A) BHF  A 602 ( 3.9A) BHF  A 602 (-3.7A) BHF  A 602 (-3.5A) BHF  A 602 ( 3.4A) BHF  A 602 ( 4.7A) BHF  A 602 (-3.7A) HEM  A 601 (-3.6A) None	0.53A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	4i8v	CYTOCHROME P450 1A1 (Homo sapiens)	6 / 12	SER A 120 PHE A 224 ASP A 313 GLY A 316 PHE A 319 ASP A 320	BHF  A 602 ( 4.5A) BHF  A 602 (-3.3A) BHF  A 602 (-3.7A) BHF  A 602 (-3.5A) BHF  A 602 ( 4.7A) BHF  A 602 (-3.7A)	1.42A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	4kt1	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4 (Homo sapiens)	5 / 12	ILE A 244 GLY A 266 ALA A 291 ILE A 277 LEU A 295	None	1.09A	9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	5hmp	UNCONVENTIONAL MYOSIN-VC (Homo sapiens)	5 / 12	ILE A 158 GLY A 432 PHE A 430 ILE A 436 LEU A 635	None	1.03A	7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	5zya	SPLICING FACTOR 3B SUBUNIT 1 (Homo sapiens)	5 / 12	ILE C 872 GLY C 880 ALA C 881 ASP C 883 LEU C 888	None	1.05A	23.33