POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens)		5 / 10HIS A  54
HIS A  56
HIS A  59
HIS A 110
ASP A 134
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 ( 3.3A)
ZN  A 261 (-3.3A)
ZN  A 262 ( 2.4A)
0.30A23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		2i7t CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
73 KDA SUBUNIT
(Homo
sapiens)		7 / 10HIS A  71
HIS A  73
HIS A  76
HIS A 158
ASP A 179
TYR A 207
HIS A 396
 ZN  A 482 (-3.5A)
ZN  A 482 ( 3.2A)
ZN  A 481 (-3.4A)
ZN  A 482 ( 3.3A)
ZN  A 481 (-2.5A)
None
SO4  A 491 (-4.0A)
0.61A23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		2i7t CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
73 KDA SUBUNIT
(Homo
sapiens)		5 / 10HIS A  76
HIS A 418
HIS A  71
ASP A 179
HIS A 158
 ZN  A 481 (-3.4A)
ZN  A 481 ( 3.4A)
ZN  A 482 (-3.5A)
ZN  A 481 (-2.5A)
ZN  A 482 ( 3.3A)
0.96A23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		2i7t CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
73 KDA SUBUNIT
(Homo
sapiens)		5 / 10HIS A 158
HIS A  71
HIS A 396
ASP A 179
HIS A 418
 ZN  A 482 ( 3.3A)
ZN  A 482 (-3.5A)
SO4  A 491 (-4.0A)
ZN  A 481 (-2.5A)
ZN  A 481 ( 3.4A)
1.02A23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		3zwf ZINC
PHOSPHODIESTERASE
ELAC PROTEIN 1
(Homo
sapiens)		6 / 10HIS A  62
HIS A  64
HIS A  67
HIS A 182
ASP A 253
HIS A 291
 ZN  A1364 (-3.5A)
ZN  A1364 ( 3.2A)
ZN  A1363 (-3.4A)
ZN  A1364 ( 3.5A)
ZN  A1363 (-2.5A)
PO4  A1365 (-3.8A)
0.30A22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		3zwf ZINC
PHOSPHODIESTERASE
ELAC PROTEIN 1
(Homo
sapiens)		5 / 10HIS A  67
HIS A 313
HIS A  62
ASP A 253
HIS A 182
 ZN  A1363 (-3.4A)
ZN  A1363 ( 3.4A)
ZN  A1364 (-3.5A)
ZN  A1363 (-2.5A)
ZN  A1364 ( 3.5A)
1.08A22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		3zwf ZINC
PHOSPHODIESTERASE
ELAC PROTEIN 1
(Homo
sapiens)		5 / 10HIS A 182
HIS A  62
HIS A 291
ASP A 253
HIS A 313
 ZN  A1364 ( 3.5A)
ZN  A1364 (-3.5A)
PO4  A1365 (-3.8A)
ZN  A1363 (-2.5A)
ZN  A1363 ( 3.4A)
0.97A22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		4ad9 BETA-LACTAMASE-LIKE
PROTEIN 2
(Homo
sapiens)		5 / 10HIS A  77
HIS A  79
HIS A  82
HIS A 145
ASP A 164
 ZN  A1001 (-3.4A)
ZN  A1001 (-3.3A)
ZN  A1000 (-3.4A)
ZN  A1001 (-3.3A)
ZN  A1000 ( 2.3A)
0.30A20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens)		6 / 10HIS A 185
HIS A 187
HIS A 190
HIS A 253
ASP A 284
HIS A 321
 ZN  A 501 (-3.6A)
ZN  A 501 ( 3.4A)
ZN  A 502 (-3.5A)
ZN  A 501 ( 3.5A)
ZN  A 502 (-2.5A)
3PE  A 503 (-3.8A)
0.34A22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens)		5 / 10HIS A 253
HIS A 185
HIS A 321
ASP A 284
HIS A 343
 ZN  A 501 ( 3.5A)
ZN  A 501 (-3.6A)
3PE  A 503 (-3.8A)
ZN  A 502 (-2.5A)
ZN  A 502 ( 3.6A)
1.02A22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		4v0h METALLO-BETA-LACTAMA
SE DOMAIN-CONTAINING
PROTEIN 1 1
(Homo
sapiens)		5 / 10HIS A 117
HIS A 119
HIS A 122
HIS A 172
ASP A 195
 FE  A1242 (-3.5A)
FE  A1242 (-3.4A)
FE  A1243 (-3.5A)
FE  A1242 (-3.4A)
FE  A1243 ( 2.4A)
0.29A20.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5aho 5' EXONUCLEASE
APOLLO
(Homo
sapiens)		6 / 10HIS A  31
HIS A  33
HIS A  36
HIS A  99
ASP A 120
HIS A 276
 ZN  A1321 (-3.3A)
ZN  A1321 ( 3.2A)
ZN  A1320 ( 3.4A)
ZN  A1321 ( 3.4A)
ZN  A1320 (-2.5A)
TLA  A1319 ( 3.9A)
0.24A35.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5aho 5' EXONUCLEASE
APOLLO
(Homo
sapiens)		6 / 10HIS A  31
HIS A  33
HIS A  36
HIS A  99
ASP A 120
THR A 257
 ZN  A1321 (-3.3A)
ZN  A1321 ( 3.2A)
ZN  A1320 ( 3.4A)
ZN  A1321 ( 3.4A)
ZN  A1320 (-2.5A)
TLA  A1322 (-3.3A)
0.66A35.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5ahr DNA CROSS-LINK
REPAIR 1A PROTEIN
(Homo
sapiens)		9 / 10HIS A 732
HIS A 734
ASP A 736
HIS A 737
HIS A 793
ASP A 815
TYR A 841
TYR A 879
HIS A 994
 ZN  A2041 (-3.4A)
ZN  A2041 (-3.1A)
None
ZN  A2041 ( 4.8A)
ZN  A2041 (-3.4A)
ZN  A2041 (-3.1A)
None
None
None
0.58A99.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5ahr DNA CROSS-LINK
REPAIR 1A PROTEIN
(Homo
sapiens)		5 / 10HIS A 793
HIS A 732
HIS A 994
ASP A 815
TYR A 879
 ZN  A2041 (-3.4A)
ZN  A2041 (-3.4A)
None
ZN  A2041 (-3.1A)
None
1.05A99.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		2gjx BETA-HEXOSAMINIDASE
ALPHA CHAIN
(Homo
sapiens)		4 / 8ASN A 379
THR A 387
GLN A 357
ILE A 356
None
0.93A23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		2gk1 BETA-HEXOSAMINIDASE
SUBUNIT ALPHA
(Homo
sapiens)		4 / 8ASN I 379
THR I 387
GLN I 357
ILE I 356
None
0.90A22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		2lfe E3 UBIQUITIN-PROTEIN
LIGASE HECW2
(Homo
sapiens)		4 / 8ASN A 110
THR A 116
ILE A 121
GLY A 119
None
0.91A16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		2pg6 CYTOCHROME P450 2A6
(Homo
sapiens)		4 / 8PHE A 238
THR A 214
GLN A 234
GLY A 217
None
0.96A21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		2xrc HUMAN COMPLEMENT
FACTOR I
(Homo
sapiens)		4 / 8ASN A 159
THR A 185
GLN A 189
GLY A 187
NAG  A 659 (-1.9A)
None
None
None
0.94A20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		3rc3 ATP-DEPENDENT RNA
HELICASE SUPV3L1,
MITOCHONDRIAL
(Homo
sapiens)		4 / 8PHE A 411
ARG A 473
ILE A 435
GLY A 472
None
ANP  A 801 (-3.0A)
None
None
0.97A19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		4hva CASPASE-6
(Homo
sapiens)		4 / 8PHE A  55
ARG A  65
THR A 222
GLY A  66
None
0.89A20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		4pj3 INTRON-BINDING
PROTEIN AQUARIUS
(Homo
sapiens)		4 / 8PHE A 802
THR A 819
ILE A 810
GLY A 813
None
1.00A12.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5ahr DNA CROSS-LINK
REPAIR 1A PROTEIN
(Homo
sapiens)		5 / 8ASN A 938
PHE A 939
THR A 962
ILE A 986
GLY A 988
None
0.58A99.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5ahr DNA CROSS-LINK
REPAIR 1A PROTEIN
(Homo
sapiens)		5 / 8PHE A 939
THR A 962
GLN A 979
ILE A 986
GLY A 988
None
1.03A99.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5fma NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 1
(Homo
sapiens)		4 / 8ASN A 264
THR A 293
GLN A 290
GLY A 289
None
1.00A17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5mnw GUANYLATE CYCLASE
SOLUBLE SUBUNIT
BETA-1
(Homo
sapiens)		5 / 8PHE A  75
THR A 160
GLN A 156
ILE A 157
GLY A 159
None
1.40A14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5w7c ACYLOXYACYL
HYDROLASE
(Homo
sapiens)		4 / 8PHE C 499
GLN C 553
ILE C 554
GLY C 556
None
0.97A11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5yz0 SERINE/THREONINE-PRO
TEIN KINASE ATR
(Homo
sapiens)		4 / 8ASN A1668
THR A2528
ILE A1662
GLY A2524
None
1.00A12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6ces RAS-RELATED
GTP-BINDING PROTEIN
C
(Homo
sapiens)		5 / 8ASN C 111
PHE C 112
ARG C  63
THR C 137
GLY C 138
None
1.00A11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens)		5 / 9PRO A 167
TYR A 169
THR A 233
THR A 234
ASP A 252
PRO  A 167 ( 1.1A)
TYR  A 169 ( 1.3A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
ASP  A 252 ( 0.6A)
1.36A18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		2qna IMPORTIN SUBUNIT
BETA-1
(Homo
sapiens)		5 / 9THR A 550
ILE A 535
TYR A 529
THR A 514
THR A 513
None
1.18A6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6c01 ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 3
(Homo
sapiens)		5 / 9THR A 214
ILE A 278
PRO A 254
THR A 318
THR A 268
None
1.50A17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens)		5 / 9PRO A 167
TYR A 169
THR A 233
THR A 234
ASP A 252
PRO  A 167 ( 1.1A)
TYR  A 169 ( 1.3A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
ASP  A 252 ( 0.6A)
1.36A18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens)		5 / 10PRO A 167
TYR A 169
THR A 233
THR A 234
ASP A 252
PRO  A 167 ( 1.1A)
TYR  A 169 ( 1.3A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
ASP  A 252 ( 0.6A)
1.35A18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_2
(BETA-LACTAMASE)		1wwy THIOREDOXIN-LIKE
PROTEIN 1
(Homo
sapiens)		4 / 4CYH A  35
ILE A 111
PRO A  71
THR A 150
None
1.19A16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_2
(BETA-LACTAMASE)		2dku KIAA1556 PROTEIN
(Homo
sapiens)		4 / 4CYH A  30
ILE A  67
PRO A  56
THR A  16
None
1.38A26.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_2
(BETA-LACTAMASE)		2lv9 HISTONE-LYSINE
N-METHYLTRANSFERASE
MLL5
(Homo
sapiens)		4 / 4CYH A 134
ILE A 144
PRO A 155
THR A 119
None
1.47A18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_2
(BETA-LACTAMASE)		3vn9 DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 6
(Homo
sapiens)		4 / 4CYH A 196
ILE A 158
PRO A 182
THR A 112
 MG  A 402 ( 3.7A)
None
None
None
1.43A12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens)		5 / 9PRO A 167
TYR A 169
THR A 233
THR A 234
ASP A 252
PRO  A 167 ( 1.1A)
TYR  A 169 ( 1.3A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
ASP  A 252 ( 0.6A)
1.33A18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6c01 ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 3
(Homo
sapiens)		5 / 9THR A 214
ILE A 278
PRO A 254
THR A 318
THR A 268
None
1.48A17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens)		5 / 9PRO A 167
TYR A 169
THR A 233
THR A 234
ASP A 252
PRO  A 167 ( 1.1A)
TYR  A 169 ( 1.3A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
ASP  A 252 ( 0.6A)
1.36A18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_C_9F2C302_1
(BETA-LACTAMASE)		1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens)		5 / 9PRO A 167
TYR A 169
THR A 233
THR A 234
ASP A 252
PRO  A 167 ( 1.1A)
TYR  A 169 ( 1.3A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
ASP  A 252 ( 0.6A)
1.38A18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_C_9F2C302_1
(BETA-LACTAMASE)		2qna IMPORTIN SUBUNIT
BETA-1
(Homo
sapiens)		5 / 9THR A 550
ILE A 535
TYR A 529
THR A 514
THR A 513
None
1.16A6.56