POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NR3_A_95EA401_0 (DNA (CYTOSINE-5)-METHYLT RANSFERASE 3B)	2h26	T-CELL SURFACE GLYCOPROTEIN CD1B (Homo sapiens)	4 / 7	ILE A  74 PHE A  75 TRP A  40 ASP A  41	None None 6UL  A 312 (-4.7A) None	1.35A	21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NR3_A_95EA401_0 (DNA (CYTOSINE-5)-METHYLT RANSFERASE 3B)	2p57	GTPASE-ACTIVATING PROTEIN ZNF289 (Homo sapiens)	4 / 7	ILE A  39 PHE A  62 TRP A  72 ASP A  69	None	1.45A	19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NR3_A_95EA401_0 (DNA (CYTOSINE-5)-METHYLT RANSFERASE 3B)	2ql6	NICOTINAMIDE RIBOSIDE KINASE 1 (Homo sapiens)	4 / 7	ILE A 161 PHE A 103 TRP A 112 TRP A 163	None	1.28A	21.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NR3_A_95EA401_0 (DNA (CYTOSINE-5)-METHYLT RANSFERASE 3B)	3llr	DNA (CYTOSINE-5)-METHYLT RANSFERASE 3A (Homo sapiens)	5 / 7	PHE A  29 TRP A  32 TRP A  56 ASP A  59 LYS A  61	BTB  A 154 (-3.2A) BTB  A 154 (-3.6A) BTB  A 154 (-3.4A) BTB  A 154 (-2.7A) BTB  A 154 (-3.6A)	1.00A	51.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NR3_A_95EA401_0 (DNA (CYTOSINE-5)-METHYLT RANSFERASE 3B)	4fzd	SERINE/THREONINE-PRO TEIN KINASE MST4 (Homo sapiens)	4 / 7	ILE B  52 PHE B  39 TRP B  96 LYS B  94	None	1.38A	21.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NR3_A_95EA401_0 (DNA (CYTOSINE-5)-METHYLT RANSFERASE 3B)	4ld6	PWWP DOMAIN-CONTAINING PROTEIN 2B (Homo sapiens)	4 / 7	ILE A 498 PHE A 501 TRP A 504 TRP A 530	GOL  A3001 (-4.7A) GOL  A3001 (-3.2A) GOL  A3001 (-3.6A) GOL  A3001 (-3.4A)	0.27A	32.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NR3_A_95EA401_0 (DNA (CYTOSINE-5)-METHYLT RANSFERASE 3B)	4o27	SERINE/THREONINE-PRO TEIN KINASE 24 (Homo sapiens)	4 / 7	ILE B  52 PHE B  39 TRP B  96 LYS B  94	None	1.46A	21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NR3_A_95EA401_0 (DNA (CYTOSINE-5)-METHYLT RANSFERASE 3B)	4twe	N-ACETYLATED-ALPHA-L INKED ACIDIC DIPEPTIDASE-LIKE PROTEIN (Homo sapiens)	4 / 7	ILE A 540 PHE A 449 ASP A 445 SER A 381	None None ZN  A 802 (-2.0A) None	1.44A	9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NR3_A_95EA401_0 (DNA (CYTOSINE-5)-METHYLT RANSFERASE 3B)	4ylr	TUBULIN POLYGLUTAMYLASE TTLL7 (Homo sapiens)	4 / 7	ILE A  52 TRP A  76 ASP A  78 LYS A  49	None	1.20A	14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NR3_A_95EA401_0 (DNA (CYTOSINE-5)-METHYLT RANSFERASE 3B)	5mio	KINESIN-LIKE PROTEIN KIF2C,KIF2C FUSED TO A DARPIN,KIF2C FUSED TO A DARPIN (Homo sapiens)	4 / 7	ILE C 449 PHE C 401 ASP C 492 SER C 470	None None MG  C 801 (-2.8A) None	1.48A	14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NR3_A_95EA401_0 (DNA (CYTOSINE-5)-METHYLT RANSFERASE 3B)	5v89	DCN1-LIKE PROTEIN 4 (Homo sapiens)	4 / 7	ILE A 262 PHE A 258 TRP A 275 ASP A 280	None	1.40A	23.00