POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens)		4 / 8THR A  67
TYR A 142
THR A 144
ARG A 121
None
1.29A19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2d0j GALACTOSYLGALACTOSYL
XYLOSYLPROTEIN
3-BETA-GLUCURONOSYLT
RANSFERASE 2
(Homo
sapiens)		4 / 8THR A 189
TYR A 190
THR A 104
GLN A 107
None
1.16A19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2xh1 KYNURENINE/ALPHA-AMI
NOADIPATE
AMINOTRANSFERASE,
MITOCHONDRIAL
(Homo
sapiens)		4 / 8THR A  99
THR A 275
ARG A 257
GLN A  91
None
1.30A16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2ybr SINGLE CHAIN
ANTIBODY FRAGMENT
9004G
(Homo
sapiens)		4 / 8TRP A 107
TYR B 219
ARG B 228
GLN B 221
None
1.17A26.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3v4v INTEGRIN BETA-7
(Homo
sapiens)		4 / 8THR B 419
ARG B 124
GLN B 122
TRP B 421
None
1.37A16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		4l7w HD DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens)		4 / 8TRP A  35
TYR A 168
THR A 171
GLN A 144
None
1.41A17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		4pgj HUMAN HEAVY CHAIN
DOMAIN ANTIBODY
(Homo
sapiens)		4 / 8TRP A 111
TYR A 110
THR A 100
GLN A 104
None
1.33A23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		4pju COHESIN SUBUNIT SA-2
DOUBLE-STRAND-BREAK
REPAIR PROTEIN RAD21
HOMOLOG
(Homo
sapiens)		4 / 8TRP B 381
THR A 626
THR A 586
GLN A 590
None
1.42A16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		4z0v 2',5'-PHOSPHODIESTER
ASE 12
(Homo
sapiens)		4 / 8THR A 236
TYR A 235
ARG A 233
TRP A 197
None
1.07A15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens)		4 / 8TYR A 701
THR A 782
GLN A 798
TRP A 784
None
1.23A15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		3ecn HIGH AFFINITY
CAMP-SPECIFIC AND
IBMX-INSENSITIVE
3',5'-CYCLIC
PHOSPHODIESTERASE 8A
(Homo
sapiens)		5 / 12SER A 561
ALA A 592
PRO A 513
TRP A 541
ALA A 593
None
1.38A18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		4a63 APOPTOSIS
STIMULATING OF P53
PROTEIN 2
(Homo
sapiens)		5 / 12PHE B1010
SER B1014
ALA B1017
ALA B1016
GLY B1015
None
1.23A17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		4a63 APOPTOSIS
STIMULATING OF P53
PROTEIN 2
(Homo
sapiens)		5 / 12SER B1014
VAL B1012
ALA B1017
ALA B1016
GLY B1015
None
1.37A17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens)		5 / 12VAL A  90
ALA A 287
TYR A 134
ALA A  87
GLY A  88
None
1.37A15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		4da1 PROTEIN PHOSPHATASE
1K, MITOCHONDRIAL
(Homo
sapiens)		5 / 12PHE A 292
VAL A 343
ALA A  98
ALA A 323
GLY A  96
None
None
None
None
BME  A 501 ( 4.5A)
1.39A16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		4fdj N-ACETYLGALACTOSAMIN
E-6-SULFATASE
(Homo
sapiens)		5 / 12SER A 287
ALA A 292
TYR A 254
ALA A 291
GLY A 290
None
1.39A16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		4nrq RNA DEMETHYLASE
ALKBH5
(Homo
sapiens)		5 / 12SER A  87
VAL A  85
ALA A 261
ALA A 260
GLY A  88
None
1.35A19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3rl7 DISKS LARGE HOMOLOG
1
(Homo
sapiens)		5 / 12LEU B 305
SER B 301
VAL B 303
ALA B 299
GLY B 300
None
1.18A18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		5nn8 LYSOSOMAL
ALPHA-GLUCOSIDASE
(Homo
sapiens)		5 / 12LEU A 587
VAL A 597
TRP A 499
ALA A 610
GLY A 611
None
0.94A11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6ehy SCFV ANTIBODY
FRAGMENT
(Homo
sapiens)		5 / 12LEU A  45
SER A  35
VAL A  37
ALA A  61
GLY A  49
None
1.19A22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		1dhs DEOXYHYPUSINE
SYNTHASE
(Homo
sapiens)		3 / 3ARG A  61
PRO A 336
TYR A 340
None
0.94A19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		1em2 MLN64 PROTEIN
(Homo
sapiens)		3 / 3ARG A 380
PRO A 373
TYR A 378
None
1.01A21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		1tf0 SERUM ALBUMIN
(Homo
sapiens)		3 / 3ARG A 337
PRO A 303
TYR A 332
None
1.00A12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		2fy2 CHOLINE
O-ACETYLTRANSFERASE
(Homo
sapiens)		3 / 3ARG A 453
PRO A 434
TYR A 529
None
0.76A13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		2pb7 E3 UBIQUITIN-PROTEIN
LIGASE UHRF1
(Homo
sapiens)		3 / 3ARG A 582
PRO A 587
TYR A 555
None
1.01A22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		3edy TRIPEPTIDYL-PEPTIDAS
E 1
(Homo
sapiens)		3 / 3ARG A 492
PRO A 563
TYR A  79
None
None
EDO  A 704 (-4.6A)
1.04A14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		3qfs NADPH--CYTOCHROME
P450 REDUCTASE
(Homo
sapiens)		3 / 3ARG A 453
PRO A 365
TYR A 326
None
0.77A16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		4idj FAB LIGHT CHAIN
(Homo
sapiens)		3 / 3ARG L  45
PRO L  59
TYR L  86
None
1.06A22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		4xnz LIGHT CHAIN OF
ANTIBODY VRC06B
(Homo
sapiens)		3 / 3ARG L  44
PRO L  58
TYR L  85
None
0.99A20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens)		3 / 3ARG A 193
PRO A  45
TYR A  88
None
0.93A21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		5fm5 OBSCURIN-LIKE-1
(Homo
sapiens)		3 / 3ARG O 296
PRO O 275
TYR O 268
None
1.00A20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		5gs1 LIGHT CHAIN
(Homo
sapiens)		3 / 3ARG A  46
PRO A  60
TYR A  87
None
1.09A20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		5uy3 ANTIBODY PGT144 FAB
LIGHT CHAIN
(Homo
sapiens)		3 / 3ARG L  45
PRO L  59
TYR L  86
None
1.07A23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		5xtb NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
12
NADH-UBIQUINONE
OXIDOREDUCTASE 75
KDA SUBUNIT,
MITOCHONDRIAL
(Homo
sapiens)		3 / 3ARG M 308
PRO M 578
TYR N 144
None
0.89A14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens)		4 / 8THR A  67
TYR A 142
THR A 144
ARG A 121
None
1.33A19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		1nun FIBROBLAST GROWTH
FACTOR-10
(Homo
sapiens)		4 / 8THR A 197
TYR A 161
THR A 163
ARG A 194
None
1.40A18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		1wi1 CALCIUM-DEPENDENT
ACTIVATOR PROTEIN
FOR SECRETION, CAPS
(Homo
sapiens)		4 / 8THR A  87
TYR A  61
THR A  62
GLN A 111
None
1.42A22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		2d0j GALACTOSYLGALACTOSYL
XYLOSYLPROTEIN
3-BETA-GLUCURONOSYLT
RANSFERASE 2
(Homo
sapiens)		4 / 8THR A 189
TYR A 190
THR A 104
GLN A 107
None
1.16A19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		2xh1 KYNURENINE/ALPHA-AMI
NOADIPATE
AMINOTRANSFERASE,
MITOCHONDRIAL
(Homo
sapiens)		4 / 8THR A  99
THR A 275
ARG A 257
GLN A  91
None
1.36A16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		3aih PROTEIN OS-9
(Homo
sapiens)		4 / 8TRP A 118
THR A 114
TYR A 120
GLN A 129
MAN  A 301 (-3.8A)
None
None
None
1.31A16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		3eh1 PROTEIN TRANSPORT
PROTEIN SEC24B
(Homo
sapiens)		4 / 8TRP A 624
THR A 610
TYR A 611
THR A 997
None
1.33A13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		3fib FIBRINOGEN GAMMA
CHAIN RESIDUES
(Homo
sapiens)		4 / 8THR A 353
TYR A 377
THR A 374
ARG A 375
None
1.34A24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		4l7w HD DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens)		4 / 8TRP A  35
TYR A 168
THR A 171
GLN A 144
None
1.31A17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		4pgj HUMAN HEAVY CHAIN
DOMAIN ANTIBODY
(Homo
sapiens)		4 / 8TRP A 111
TYR A 110
THR A 100
GLN A 104
None
1.28A23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		4pju COHESIN SUBUNIT SA-2
DOUBLE-STRAND-BREAK
REPAIR PROTEIN RAD21
HOMOLOG
(Homo
sapiens)		4 / 8TRP B 381
THR A 626
THR A 586
GLN A 590
None
1.33A16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		5vni PROTEIN TRANSPORT
PROTEIN SEC24A
(Homo
sapiens)		4 / 8TRP B 450
THR B 436
TYR B 437
THR B 822
None
ZN  B1101 ( 4.6A)
None
None
1.27A11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens)		4 / 8TYR A 701
THR A 782
GLN A 798
TRP A 784
None
1.26A15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3ecn HIGH AFFINITY
CAMP-SPECIFIC AND
IBMX-INSENSITIVE
3',5'-CYCLIC
PHOSPHODIESTERASE 8A
(Homo
sapiens)		5 / 12SER A 561
ALA A 592
PRO A 513
TRP A 541
ALA A 593
None
1.37A18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens)		5 / 12VAL A  90
ALA A 287
TYR A 134
ALA A  87
GLY A  88
None
1.34A15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		4fdj N-ACETYLGALACTOSAMIN
E-6-SULFATASE
(Homo
sapiens)		5 / 12SER A 287
ALA A 292
TYR A 254
ALA A 291
GLY A 290
None
1.36A16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		4nrq RNA DEMETHYLASE
ALKBH5
(Homo
sapiens)		5 / 12SER A  87
VAL A  85
ALA A 261
ALA A 260
GLY A  88
None
1.34A19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		4o0e ISOASPARTYL
PEPTIDASE/L-ASPARAGI
NASE
(Homo
sapiens)		5 / 12VAL A  48
ALA A  54
PRO A   3
ALA A  51
GLY A  50
None
1.34A20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		5c16 MYOTUBULARIN-RELATED
PROTEIN 1
(Homo
sapiens)		5 / 12VAL A 288
ALA A 281
PRO A 262
ALA A 280
GLY A 286
None
1.34A17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		5jz7 MEDI578 SCFV, HEAVY
CHAIN
MEDI578 SCFV, LIGHT
CHAIN
(Homo
sapiens)		5 / 12SER C  35
VAL C  37
ALA C  60
TRP D  91
GLY C  49
None
1.13A26.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens)		4 / 8THR A  67
TYR A 142
THR A 144
ARG A 121
None
1.33A19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		2d0j GALACTOSYLGALACTOSYL
XYLOSYLPROTEIN
3-BETA-GLUCURONOSYLT
RANSFERASE 2
(Homo
sapiens)		4 / 8THR A 189
TYR A 190
THR A 104
GLN A 107
None
1.13A19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		2xh1 KYNURENINE/ALPHA-AMI
NOADIPATE
AMINOTRANSFERASE,
MITOCHONDRIAL
(Homo
sapiens)		4 / 8THR A  99
THR A 275
ARG A 257
GLN A  91
None
1.30A16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		3aih PROTEIN OS-9
(Homo
sapiens)		4 / 8TRP A 118
THR A 114
TYR A 120
GLN A 129
MAN  A 301 (-3.8A)
None
None
None
1.35A16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		3v4v INTEGRIN BETA-7
(Homo
sapiens)		4 / 8THR B 419
ARG B 124
GLN B 122
TRP B 421
None
1.37A16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		4l7w HD DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens)		4 / 8TRP A  35
TYR A 168
THR A 171
GLN A 144
None
1.41A17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		4pgj HUMAN HEAVY CHAIN
DOMAIN ANTIBODY
(Homo
sapiens)		4 / 8TRP A 111
TYR A 110
THR A 100
GLN A 104
None
1.32A23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		4pju COHESIN SUBUNIT SA-2
DOUBLE-STRAND-BREAK
REPAIR PROTEIN RAD21
HOMOLOG
(Homo
sapiens)		4 / 8TRP B 381
THR A 626
THR A 586
GLN A 590
None
1.39A16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		5foe GDP-FUCOSE PROTEIN
O-FUCOSYLTRANSFERASE
2,THROMBOSPONDIN-1
(Caenorhabditis
elegans;
Homo
sapiens)		4 / 8TRP A 141
TYR A 145
ARG A1025
GLN A1042
None
1.34A16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens)		4 / 8TYR A 701
THR A 782
GLN A 798
TRP A 784
None
1.20A15.96