POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_A_6ELA501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 5	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.50A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_B_6ELB501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 5	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.45A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_D_6ELD501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 5	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.48A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_E_6ELE501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 5	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.42A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_G_6ELG501_0 (PROTEIN CEREBLON)	2xyd	ANGIOTENSIN-CONVERTI NG ENZYME (Homo sapiens)	4 / 8	HIS A 365 TRP A 335 HIS A 491 THR A 496	ZN  A1620 ( 3.2A) PEG  A1622 ( 4.0A) 3ES  A1611 (-3.9A) 3ES  A1611 (-3.4A)	1.45A	10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_G_6ELG501_0 (PROTEIN CEREBLON)	4f0x	MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL (Homo sapiens)	4 / 8	TRP A 189 PHE A 194 HIS A 143 THR A  60	None	1.25A	12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_G_6ELG501_0 (PROTEIN CEREBLON)	5dgo	CELL DIVISION CONTROL PROTEIN 45 HOMOLOG (Homo sapiens)	4 / 8	HIS A 541 TRP A  55 HIS A 194 THR A 100	None	1.28A	12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_G_6ELG501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 8	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.48A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_G_6ELG501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 8	TRP Z 386 TRP Z 400 PHE Z 402 HIS Z 353	85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None 85C  Z 502 (-3.9A)	1.23A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_H_6ELH501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 5	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.43A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_J_6ELJ501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 5	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.41A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_K_6ELK501_0 (PROTEIN CEREBLON)	2is7	ALDOSE REDUCTASE (Homo sapiens)	4 / 7	HIS A 306 TRP A  79 PHE A 122 THR A 140	None None 2CL  A 317 ( 4.9A) None	1.47A	15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_K_6ELK501_0 (PROTEIN CEREBLON)	4yo2	TRANSCRIPTION FACTOR E2F8 (Homo sapiens)	4 / 7	HIS A 181 TRP A 180 PHE A 125 THR A 189	None	1.48A	17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_K_6ELK501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 7	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.43A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_M_6ELM501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 5	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.43A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_N_6ELN501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 5	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.41A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_P_6ELP501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 5	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.44A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_Q_6ELQ501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 5	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.44A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_S_6ELS501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 5	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.42A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_T_6ELT501_0 (PROTEIN CEREBLON)	2xyd	ANGIOTENSIN-CONVERTI NG ENZYME (Homo sapiens)	4 / 8	HIS A 491 THR A 496 HIS A 365 TRP A 335	3ES  A1611 (-3.9A) 3ES  A1611 (-3.4A) ZN  A1620 ( 3.2A) PEG  A1622 ( 4.0A)	1.39A	10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_T_6ELT501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 8	HIS Z 353 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.9A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	1.25A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_T_6ELT501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 8	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.51A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_V_6ELV501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 5	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.39A	27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_Y_6ELY501_0 (PROTEIN CEREBLON)	2is7	ALDOSE REDUCTASE (Homo sapiens)	4 / 7	THR A 140 HIS A 306 TRP A  79 PHE A 122	None None None 2CL  A 317 ( 4.9A)	1.48A	15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_Y_6ELY501_0 (PROTEIN CEREBLON)	4yo2	TRANSCRIPTION FACTOR E2F8 (Homo sapiens)	4 / 7	THR A 189 HIS A 181 TRP A 180 PHE A 125	None	1.49A	17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJ1_Y_6ELY501_0 (PROTEIN CEREBLON)	5hxb	PROTEIN CEREBLON (Homo sapiens)	4 / 7	TRP Z 380 TRP Z 386 TRP Z 400 PHE Z 402	85C  Z 502 (-3.2A) 85C  Z 502 (-3.4A) 85C  Z 502 (-3.7A) None	0.40A	27.62