POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	1rjb	FL CYTOKINE RECEPTOR (Homo sapiens)	7 / 12	LEU A 616 VAL A 624 ALA A 642 LYS A 644 GLY A 697 ASP A 698 LEU A 818	None	0.55A	36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	1t46	HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG (Homo sapiens)	7 / 12	LEU A 595 VAL A 603 ALA A 621 LYS A 623 GLY A 676 ASP A 677 LEU A 799	STI  A   3 ( 3.8A) STI  A   3 ( 4.6A) STI  A   3 (-3.5A) STI  A   3 (-3.7A) STI  A   3 ( 3.8A) None STI  A   3 (-4.4A)	0.54A	34.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	1zlt	SERINE/THREONINE-PRO TEIN KINASE CHK1 (Homo sapiens)	8 / 12	LEU A  15 GLY A  18 VAL A  23 ALA A  36 LYS A  38 LEU A  84 GLY A  90 LEU A 137	HYM  A 400 (-4.2A) HYM  A 400 ( 3.7A) HYM  A 400 (-4.3A) HYM  A 400 (-3.5A) HYM  A 400 (-3.2A) HYM  A 400 (-4.2A) None HYM  A 400 (-4.5A)	0.80A	23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	1zlt	SERINE/THREONINE-PRO TEIN KINASE CHK1 (Homo sapiens)	8 / 12	LEU A  15 VAL A  23 ALA A  36 LYS A  38 LEU A  84 GLY A  90 LEU A 137 ASP A 148	HYM  A 400 (-4.2A) HYM  A 400 (-4.3A) HYM  A 400 (-3.5A) HYM  A 400 (-3.2A) HYM  A 400 (-4.2A) None HYM  A 400 (-4.5A) HYM  A 400 (-3.9A)	0.67A	23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	1zws	DAP-KINASE RELATED PROTEIN 1 (Homo sapiens)	7 / 12	LEU A  19 VAL A  27 ALA A  40 LYS A  42 LEU A  93 LEU A  95 ASP A 161	None	0.57A	23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2a2a	DEATH-ASSOCIATED PROTEIN KINASE 2 (Homo sapiens)	7 / 12	LEU A  19 VAL A  27 ALA A  40 LYS A  42 LEU A  93 LEU A  95 ASP A 161	None None GOL  A3001 (-3.5A) None GOL  A3001 ( 4.5A) None None	0.63A	22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2buj	SERINE/THREONINE-PRO TEIN KINASE 16 (Homo sapiens)	7 / 12	LEU A  26 VAL A  34 ALA A  47 LEU A  98 GLY A 104 LEU A 155 ASP A 166	STU  A1301 (-4.2A) STU  A1301 (-4.8A) STU  A1301 (-3.6A) STU  A1301 ( 4.7A) STU  A1301 ( 4.0A) STU  A1301 ( 4.8A) None	0.72A	25.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 12	LEU X  17 VAL X  25 ALA X  37 LYS X  39 GLY X  88 LEU X 137 ASP X 148	STU  X 902 (-3.8A) STU  X 902 ( 4.8A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) STU  X 902 (-3.5A) STU  X 902 (-4.4A) STU  X 902 (-3.6A)	0.68A	35.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2eu9	DUAL SPECIFICITY PROTEIN KINASE CLK3 (Homo sapiens)	7 / 12	LEU A 162 VAL A 170 ALA A 184 LYS A 186 LEU A 238 LEU A 290 ASP A 320	None	0.72A	23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2h8h	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	7 / 12	LEU A 273 VAL A 281 ALA A 293 LYS A 295 GLY A 344 LEU A 393 ASP A 404	H8H  A 534 (-3.8A) H8H  A 534 (-4.4A) H8H  A 534 (-3.2A) H8H  A 534 (-3.7A) H8H  A 534 (-3.3A) H8H  A 534 (-4.5A) H8H  A 534 (-4.2A)	0.89A	25.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	7 / 12	LEU A 251 VAL A 259 ALA A 271 LYS A 273 GLY A 322 LEU A 371 ASP A 382	1BM  A 499 ( 3.7A) 1BM  A 499 ( 4.8A) 1BM  A 499 (-3.6A) 1BM  A 499 (-3.8A) 1BM  A 499 (-3.5A) 1BM  A 499 (-4.4A) 1BM  A 499 (-4.4A)	0.64A	33.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	LEU A 248 GLY A 250 VAL A 256 ALA A 269 LYS A 271 GLY A 321 LEU A 370 ASP A 381	GIN  A 600 ( 4.6A) None GIN  A 600 ( 4.7A) GIN  A 600 (-3.1A) GIN  A 600 (-3.6A) None GIN  A 600 (-4.7A) GIN  A 600 (-4.9A)	0.97A	33.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2jgz	CELL DIVISION PROTEIN KINASE 2 (Homo sapiens)	7 / 12	GLY A  13 VAL A  18 ALA A  31 LYS A  33 ASP A  86 LEU A 134 ASP A 145	None	0.97A	22.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2ogv	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR PRECURSOR (Homo sapiens)	7 / 12	LEU A 588 VAL A 596 ALA A 614 LYS A 616 GLY A 669 ASP A 670 LEU A 785	None	0.52A	33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2ogv	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR PRECURSOR (Homo sapiens)	7 / 12	LEU A 588 VAL A 596 ALA A 614 LYS A 616 GLY A 669 LEU A 785 ASP A 796	None	0.70A	33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2qob	EPHRIN RECEPTOR (Homo sapiens)	7 / 12	VAL A 635 ALA A 651 LYS A 653 GLY A 705 SER A 709 LEU A 753 ASP A 764	BME  A   1 (-4.9A) PTR  A 701 ( 4.7A) None None None None None	0.68A	33.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2r4b	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 (Homo sapiens)	7 / 12	LEU A 724 VAL A 732 ALA A 749 LYS A 751 LEU A 798 GLY A 802 LEU A 850	GW7  A   1 ( 4.2A) GW7  A   1 ( 4.8A) GW7  A   1 (-3.3A) GW7  A   1 (-3.9A) GW7  A   1 (-4.5A) GW7  A   1 (-3.6A) GW7  A   1 (-4.2A)	0.68A	32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2w4k	DEATH-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	7 / 12	LEU A  19 VAL A  27 ALA A  40 LYS A  42 LEU A  93 LEU A  95 ASP A 161	ADP  A1303 ( 3.9A) ADP  A1303 (-4.0A) ADP  A1303 (-3.5A) ADP  A1303 (-2.7A) ADP  A1303 ( 4.1A) None MG  A1304 ( 2.8A)	0.61A	25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2w4k	DEATH-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	7 / 12	LEU A  19 VAL A  27 LYS A  42 LEU A  93 LEU A  95 GLY A  99 ASP A 161	ADP  A1303 ( 3.9A) ADP  A1303 (-4.0A) ADP  A1303 (-2.7A) ADP  A1303 ( 4.1A) None None MG  A1304 ( 2.8A)	0.87A	25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2xk9	CHECKPOINT KINASE 2 (Homo sapiens)	7 / 12	LEU A 226 VAL A 234 ALA A 247 LYS A 249 LEU A 303 GLY A 307 LEU A 354	XK9  A1511 (-3.8A) XK9  A1511 (-4.8A) XK9  A1511 ( 4.1A) XK9  A1511 (-4.2A) XK9  A1511 (-4.1A) XK9  A1511 ( 3.7A) XK9  A1511 (-4.6A)	1.13A	25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	10 / 12	LEU A  68 GLY A  71 VAL A  76 ALA A  92 LYS A  94 LEU A 141 GLY A 147 ASP A 148 LEU A 194 ASP A 205	STU  A   1 (-3.8A) STU  A   1 ( 4.1A) None STU  A   1 (-3.3A) STU  A   1 (-2.8A) STU  A   1 ( 4.6A) STU  A   1 ( 3.9A) STU  A   1 (-3.8A) STU  A   1 (-4.6A) STU  A   1 ( 3.8A)	0.75A	23.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2z8c	INSULIN RECEPTOR (Homo sapiens)	10 / 12	LEU A1002 GLY A1005 VAL A1010 ALA A1028 LYS A1030 LEU A1078 GLY A1082 ASP A1083 SER A1086 ASP A1150	S91  A   1 ( 4.1A) None S91  A   1 ( 4.9A) S91  A   1 (-3.2A) S91  A   1 ( 4.2A) S91  A   1 (-4.7A) S91  A   1 (-3.3A) S91  A   1 (-3.7A) None None	0.76A	37.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	2z8c	INSULIN RECEPTOR (Homo sapiens)	7 / 12	LEU A1002 GLY A1008 VAL A1010 ALA A1028 LYS A1030 LEU A1078 ASP A1150	S91  A   1 ( 4.1A) None S91  A   1 ( 4.9A) S91  A   1 (-3.2A) S91  A   1 ( 4.2A) S91  A   1 (-4.7A) None	1.18A	37.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3bqr	DEATH-ASSOCIATED PROTEIN KINASE 3 (Homo sapiens)	7 / 12	LEU A  19 VAL A  27 ALA A  40 LYS A  42 LEU A  93 LEU A  95 ASP A 161	4RB  A 401 ( 3.9A) 4RB  A 401 ( 4.4A) 4RB  A 401 (-3.3A) 4RB  A 401 ( 2.8A) 4RB  A 401 ( 4.1A) 4RB  A 401 (-4.4A) GOL  A 503 ( 3.1A)	0.50A	23.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3c4f	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	7 / 12	LEU A 484 GLY A 490 VAL A 492 ALA A 512 GLY A 567 LEU A 630 ASP A 641	C4F  A   1 ( 3.9A) None None C4F  A   1 (-3.3A) None C4F  A   1 (-4.6A) C4F  A   1 (-4.5A)	0.83A	36.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3f2a	PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE PIM-1 (Homo sapiens)	7 / 12	LEU A  44 GLY A  50 VAL A  52 ALA A  65 LYS A  67 LEU A 120 ASP A 186	985  A   1 (-4.1A) None 985  A   1 (-4.5A) 985  A   1 (-3.5A) 985  A   1 ( 2.8A) 985  A   1 (-4.3A) 985  A   1 ( 4.0A)	1.07A	24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3f2a	PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE PIM-1 (Homo sapiens)	8 / 12	LEU A  44 VAL A  52 ALA A  65 LYS A  67 LEU A 120 ASP A 128 LEU A 174 ASP A 186	985  A   1 (-4.1A) 985  A   1 (-4.5A) 985  A   1 (-3.5A) 985  A   1 ( 2.8A) 985  A   1 (-4.3A) 985  A   1 (-4.7A) 985  A   1 (-4.8A) 985  A   1 ( 4.0A)	0.86A	24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3fzp	PROTEIN TYROSINE KINASE 2 BETA (Homo sapiens)	8 / 12	LEU A 431 GLY A 434 VAL A 439 ALA A 455 LYS A 457 LEU A 504 GLY A 508 LEU A 556	AGS  A 999 ( 4.4A) AGS  A 999 (-3.0A) AGS  A 999 (-4.6A) AGS  A 999 (-3.6A) AGS  A 999 (-2.5A) AGS  A 999 (-4.4A) None AGS  A 999 (-4.5A)	0.64A	35.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3hng	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	7 / 12	LEU A 833 VAL A 841 ALA A 859 LYS A 861 GLY A 915 LEU A1029 ASP A1040	8ST  A2001 ( 4.7A) 8ST  A2001 ( 4.6A) 8ST  A2001 ( 3.8A) 8ST  A2001 (-4.0A) None None None	0.77A	30.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3i6u	SERINE/THREONINE-PRO TEIN KINASE CHK2 (Homo sapiens)	8 / 12	LEU A 226 GLY A 229 VAL A 234 ALA A 247 LEU A 301 GLY A 307 LEU A 354 ASP A 368	None	0.96A	23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3i6u	SERINE/THREONINE-PRO TEIN KINASE CHK2 (Homo sapiens)	8 / 12	LEU A 226 GLY A 229 VAL A 234 ALA A 247 LEU A 301 LEU A 303 GLY A 307 LEU A 354	None	0.84A	23.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	9 / 12	LEU A1005 GLY A1008 VAL A1013 ALA A1031 LYS A1033 LEU A1081 GLY A1085 ASP A1086 SER A1089	None None None None CCX  A   1 ( 3.7A) None None None None	0.70A	37.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3mi9	CELL DIVISION PROTEIN KINASE 9 (Homo sapiens)	6 / 12	VAL A  33 ALA A  46 LYS A  48 ASP A 109 LEU A 156 ASP A 167	None	0.59A	23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3mvj	CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	7 / 12	LEU A  49 VAL A  57 ALA A  70 GLY A 126 SER A 130 LEU A 173 ASP A 184	XFE  A 351 (-4.2A) XFE  A 351 ( 4.5A) XFE  A 351 (-3.2A) None None XFE  A 351 (-4.6A) None	0.94A	25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3nuu	PKB-LIKE (Homo sapiens)	9 / 12	LEU A  88 GLY A  91 VAL A  96 ALA A 109 LYS A 111 LEU A 159 GLY A 165 LEU A 212 ASP A 223	JOZ  A 361 (-4.1A) SO4  A   5 ( 4.4A) JOZ  A 361 ( 4.7A) JOZ  A 361 (-3.4A) SO4  A   5 (-2.8A) JOZ  A 361 (-4.0A) None None SO4  A   5 ( 4.5A)	0.77A	22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	11 / 12	LEU A 192 GLY A 195 VAL A 200 ALA A 213 LYS A 215 LEU A 263 LEU A 265 GLY A 269 ASP A 270 LEU A 318 ASP A 329	AMP  A 577 ( 4.3A) AMP  A 577 (-3.4A) AMP  A 577 (-4.3A) AMP  A 577 (-3.4A) AMP  A 577 (-2.8A) AMP  A 577 ( 4.7A) AMP  A 577 ( 4.9A) None AMP  A 577 (-3.6A) AMP  A 577 (-4.8A) AMP  A 577 (-4.0A)	0.60A	21.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3pp0	RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (Homo sapiens)	8 / 12	LEU A 726 GLY A 729 VAL A 734 ALA A 751 LYS A 753 LEU A 800 GLY A 804 LEU A 852	03Q  A   1 (-3.8A) 03Q  A   1 (-3.3A) 03Q  A   1 (-4.5A) 03Q  A   1 (-3.1A) 03Q  A   1 (-4.7A) 03Q  A   1 (-4.6A) 03Q  A   1 ( 3.9A) 03Q  A   1 (-4.4A)	0.74A	31.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3q4t	ACTIVIN RECEPTOR TYPE-2A (Homo sapiens)	7 / 12	GLY A 201 VAL A 206 ALA A 217 LYS A 219 GLY A 273 LEU A 329 ASP A 340	None TAK  A   2 ( 4.9A) TAK  A   2 (-3.5A) TAK  A   2 (-2.9A) TAK  A   2 (-3.6A) TAK  A   2 (-4.6A) None	0.80A	28.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	7 / 12	LEU A 361 VAL A 369 ALA A 382 GLY A 439 ASP A 440 LEU A 486 ASP A 497	07U  A   1 ( 4.8A) 07U  A   1 (-4.8A) 07U  A   1 (-3.3A) None 07U  A   1 (-3.9A) 07U  A   1 (-4.3A) 07U  A   1 (-3.6A)	0.84A	26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	7 / 12	LEU A 361 VAL A 369 ALA A 382 LYS A 384 ASP A 440 LEU A 486 ASP A 497	07U  A   1 ( 4.8A) 07U  A   1 (-4.8A) 07U  A   1 (-3.3A) 07U  A   1 (-3.0A) 07U  A   1 (-3.9A) 07U  A   1 (-4.3A) 07U  A   1 (-3.6A)	0.81A	26.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3v5q	NT-3 GROWTH FACTOR RECEPTOR (Homo sapiens)	6 / 12	LEU A 544 VAL A 552 ALA A 570 GLY A 623 ASP A 624 LEU A 686	0F4  A 902 ( 4.2A) None 0F4  A 902 (-3.2A) 0F4  A 902 (-3.4A) None 0F4  A 902 (-4.5A)	0.42A	37.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3w18	AURORA KINASE A (Homo sapiens)	7 / 12	LEU A 139 VAL A 147 ALA A 160 LYS A 162 LEU A 210 GLY A 216 LEU A 263	N13  A 501 (-3.7A) N13  A 501 ( 4.7A) N13  A 501 ( 4.1A) N13  A 501 (-2.9A) N13  A 501 ( 4.8A) N13  A 501 (-3.5A) N13  A 501 (-4.5A)	0.86A	23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3wig	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 (Homo sapiens)	6 / 12	LEU A  75 VAL A  83 ALA A  96 LYS A  98 GLY A 150 LEU A 198	ANP  A 401 (-3.8A) ANP  A 401 ( 4.3A) ANP  A 401 (-3.2A) ANP  A 401 (-2.7A) ANP  A 401 ( 4.3A) ANP  A 401 (-4.8A)	0.59A	22.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	7 / 12	LEU A1951 GLY A1957 VAL A1959 ALA A1978 LYS A1980 LEU A2026 LEU A2028	VGH  A3000 ( 4.4A) None None VGH  A3000 (-3.4A) VGH  A3000 ( 4.7A) VGH  A3000 ( 4.2A) VGH  A3000 ( 4.8A)	1.22A	45.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3zbf	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS (Homo sapiens)	10 / 12	LEU A1951 VAL A1959 ALA A1978 LYS A1980 LEU A2026 LEU A2028 GLY A2032 ASP A2033 LEU A2086 ASP A2102	VGH  A3000 ( 4.4A) None VGH  A3000 (-3.4A) VGH  A3000 ( 4.7A) VGH  A3000 ( 4.2A) VGH  A3000 ( 4.8A) VGH  A3000 (-3.5A) VGH  A3000 (-4.5A) VGH  A3000 (-4.3A) None	0.55A	45.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3zfx	EPHRIN TYPE-B RECEPTOR 1 (Homo sapiens)	7 / 12	VAL A 633 ALA A 649 LYS A 651 GLY A 703 SER A 707 LEU A 751 ASP A 762	None	0.54A	31.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4a4l	SERINE/THREONINE-PRO TEIN KINASE PLK1 (Homo sapiens)	7 / 12	LEU A  59 GLY A  62 ALA A  80 LYS A  82 LEU A 130 LEU A 132 ASP A 194	939  A1331 (-3.7A) 939  A1331 ( 3.7A) 939  A1331 (-3.5A) 939  A1331 (-2.6A) 939  A1331 ( 4.7A) 939  A1331 (-4.4A) 939  A1331 (-3.1A)	0.61A	24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4af3	AURORA KINASE B (Homo sapiens)	7 / 12	LEU A  83 GLY A  89 VAL A  91 ALA A 104 LYS A 106 LEU A 154 GLY A 160	VX6  A 500 (-3.8A) None VX6  A 500 ( 4.8A) VX6  A 500 (-3.4A) VX6  A 500 (-3.3A) None VX6  A 500 (-3.3A)	0.88A	23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4af3	AURORA KINASE B (Homo sapiens)	7 / 12	LEU A  83 VAL A  91 ALA A 104 LYS A 106 LEU A 154 GLY A 160 LEU A 207	VX6  A 500 (-3.8A) VX6  A 500 ( 4.8A) VX6  A 500 (-3.4A) VX6  A 500 (-3.3A) None VX6  A 500 (-3.3A) VX6  A 500 (-4.6A)	0.75A	23.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4agd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	6 / 12	LEU A 840 VAL A 848 ALA A 866 LYS A 868 GLY A 922 LEU A1035	B49  A2000 (-3.7A) None B49  A2000 (-3.5A) B49  A2000 (-3.0A) B49  A2000 ( 3.7A) B49  A2000 (-4.5A)	0.58A	35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4at3	BDNF/NT-3 GROWTH FACTORS RECEPTOR (Homo sapiens)	7 / 12	LEU A 560 GLY A 563 VAL A 568 ALA A 586 GLY A 639 ASP A 640 LEU A 699	LTI  A1839 ( 4.2A) None None LTI  A1839 (-3.3A) LTI  A1839 (-3.4A) None LTI  A1839 (-4.2A)	1.45A	37.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4at3	BDNF/NT-3 GROWTH FACTORS RECEPTOR (Homo sapiens)	7 / 12	LEU A 560 VAL A 568 ALA A 586 GLY A 639 ASP A 640 LEU A 699 ASP A 710	LTI  A1839 ( 4.2A) None LTI  A1839 (-3.3A) LTI  A1839 (-3.4A) None LTI  A1839 (-4.2A) None	0.57A	37.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4aw5	EPHRIN TYPE-B RECEPTOR 4 (Homo sapiens)	8 / 12	GLY A 100 VAL A 105 ALA A 121 LYS A 123 GLY A 175 SER A 179 LEU A 223 ASP A 234	30K  A1365 ( 4.4A) 30K  A1365 ( 4.6A) 30K  A1365 (-3.2A) 30K  A1365 (-3.8A) 30K  A1365 (-3.5A) None 30K  A1365 (-4.5A) 30K  A1365 (-3.3A)	0.50A	32.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4b6l	SERINE/THREONINE-PRO TEIN KINASE PLK3 (Homo sapiens)	6 / 12	LEU A  68 ALA A  89 LYS A  91 LEU A 139 LEU A 141 ASP A 203	9ZP  A1333 (-3.9A) 9ZP  A1333 (-3.5A) None 9ZP  A1333 (-3.8A) 9ZP  A1333 (-4.7A) None	0.51A	23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4b99	MITOGEN-ACTIVATED PROTEIN KINASE 7 (Homo sapiens)	8 / 12	GLY A  64 VAL A  69 ALA A  82 LYS A  84 LEU A 137 LEU A 139 ASP A 143 LEU A 189	None R4L  A1394 (-4.0A) R4L  A1394 ( 3.7A) None R4L  A1394 (-3.9A) R4L  A1394 ( 4.9A) R4L  A1394 ( 4.2A) R4L  A1394 (-4.5A)	0.73A	24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4b99	MITOGEN-ACTIVATED PROTEIN KINASE 7 (Homo sapiens)	8 / 12	GLY A  64 VAL A  69 LYS A  84 LEU A 137 LEU A 139 ASP A 143 LEU A 189 ASP A 200	None R4L  A1394 (-4.0A) None R4L  A1394 (-3.9A) R4L  A1394 ( 4.9A) R4L  A1394 ( 4.2A) R4L  A1394 (-4.5A) None	0.74A	24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4crs	SERINE/THREONINE-PRO TEIN KINASE N2 (Homo sapiens)	8 / 12	LEU A 663 VAL A 671 ALA A 684 LYS A 686 GLY A 743 ASP A 744 LEU A 789 ASP A 800	AGS  A1985 (-4.2A) AGS  A1985 (-4.6A) AGS  A1985 (-3.5A) AGS  A1985 (-3.0A) None AGS  A1985 (-4.0A) AGS  A1985 (-4.8A) AGS  A1985 ( 3.3A)	0.66A	25.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4e93	TYROSINE-PROTEIN KINASE FES/FPS (Homo sapiens)	9 / 12	GLY A 570 VAL A 575 ALA A 588 LYS A 590 LEU A 638 GLY A 642 ASP A 643 LEU A 690 ASP A 701	GUI  A 901 (-3.4A) GUI  A 901 (-4.5A) GUI  A 901 (-3.4A) GUI  A 901 (-2.8A) GUI  A 901 (-4.4A) GUI  A 901 (-3.5A) GUI  A 901 ( 4.8A) GUI  A 901 (-4.3A) GUI  A 901 ( 4.1A)	0.46A	36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4f0i	HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR (Homo sapiens)	7 / 12	LEU A 515 VAL A 523 ALA A 541 GLY A 594 ASP A 595 LEU A 656 ASP A 667	None	0.74A	35.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4f4p	TYROSINE-PROTEIN KINASE SYK (Homo sapiens)	7 / 12	LEU A 377 VAL A 385 ALA A 400 LYS A 402 GLY A 454 LEU A 501 ASP A 512	0SB  A 701 ( 3.9A) 0SB  A 701 (-4.0A) 0SB  A 701 (-3.3A) 0SB  A 701 ( 4.8A) 0SB  A 701 (-3.5A) 0SB  A 701 (-4.4A) 0SB  A 701 (-3.9A)	0.53A	29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4fg8	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE 1 (Homo sapiens)	7 / 12	LEU A  26 GLY A  29 VAL A  34 LYS A  49 LEU A  97 GLY A 101 LEU A 148	ATP  A 401 (-3.8A) ATP  A 401 (-3.2A) ATP  A 401 (-4.1A) ATP  A 401 (-3.0A) ATP  A 401 ( 4.8A) None ATP  A 401 (-4.6A)	0.95A	23.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	10 / 12	LEU A1122 GLY A1125 VAL A1130 ALA A1148 LYS A1150 LEU A1196 LEU A1198 ASP A1203 LEU A1256 ASP A1270	0UV  A1501 (-3.8A) 0UV  A1501 (-3.6A) 0UV  A1501 (-4.5A) 0UV  A1501 (-3.4A) 0UV  A1501 (-3.7A) 0UV  A1501 (-3.7A) 0UV  A1501 ( 4.8A) 0UV  A1501 ( 4.6A) 0UV  A1501 (-4.6A) 0UV  A1501 ( 4.2A)	0.69A	99.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	10 / 12	LEU A1122 VAL A1130 ALA A1148 LYS A1150 LEU A1196 GLY A1202 ASP A1203 SER A1206 LEU A1256 ASP A1270	0UV  A1501 (-3.8A) 0UV  A1501 (-4.5A) 0UV  A1501 (-3.4A) 0UV  A1501 (-3.7A) 0UV  A1501 (-3.7A) 0UV  A1501 (-3.6A) 0UV  A1501 ( 4.6A) None 0UV  A1501 (-4.6A) 0UV  A1501 ( 4.2A)	0.73A	99.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	10 / 12	LEU A1122 VAL A1130 ALA A1148 LYS A1150 LEU A1196 LEU A1198 GLY A1202 ASP A1203 LEU A1256 ASP A1270	0UV  A1501 (-3.8A) 0UV  A1501 (-4.5A) 0UV  A1501 (-3.4A) 0UV  A1501 (-3.7A) 0UV  A1501 (-3.7A) 0UV  A1501 ( 4.8A) 0UV  A1501 (-3.6A) 0UV  A1501 ( 4.6A) 0UV  A1501 (-4.6A) 0UV  A1501 ( 4.2A)	0.54A	99.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4fr4	SERINE/THREONINE-PRO TEIN KINASE 32A (Homo sapiens)	7 / 12	VAL A  37 ALA A  50 LEU A 102 GLY A 106 ASP A 107 LEU A 153 ASP A 164	STU  A 401 ( 4.9A) STU  A 401 (-3.2A) STU  A 401 (-4.4A) STU  A 401 ( 3.7A) STU  A 401 (-3.3A) STU  A 401 (-4.7A) STU  A 401 ( 3.9A)	0.51A	23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 VAL A 836 ALA A 853 LYS A 855 GLY A 908 LEU A 956 ASP A 967	19S  A1201 (-3.9A) 19S  A1201 (-4.4A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A) 19S  A1201 ( 4.1A)	0.79A	27.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4hzs	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	9 / 12	LEU A 132 GLY A 135 VAL A 140 ALA A 156 LYS A 158 LEU A 207 GLY A 211 LEU A 259 ASP A 270	None	0.85A	33.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4id7	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	8 / 12	LEU A 132 VAL A 140 ALA A 156 LYS A 158 LEU A 207 GLY A 211 LEU A 259 ASP A 270	1G0  A 401 ( 4.5A) 1G0  A 401 (-4.4A) 1G0  A 401 (-3.6A) 1G0  A 401 (-3.7A) 1G0  A 401 ( 4.9A) 1G0  A 401 ( 4.5A) 1G0  A 401 (-4.6A) None	0.60A	32.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4idt	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 (Homo sapiens)	8 / 12	LEU A 406 GLY A 409 VAL A 414 ALA A 427 LYS A 429 LEU A 471 GLY A 475 LEU A 522	T28  A 701 (-3.8A) T28  A 701 ( 3.0A) T28  A 701 (-4.7A) T28  A 701 (-3.0A) T28  A 701 ( 3.8A) T28  A 701 ( 4.8A) T28  A 701 ( 3.0A) T28  A 701 (-3.9A)	0.78A	25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4jxf	SERINE/THREONINE-PRO TEIN KINASE PLK4 (Homo sapiens)	6 / 12	LEU A  18 VAL A  26 ALA A  39 LEU A  89 GLY A  95 LEU A 143	631  A 301 (-3.4A) 631  A 301 (-4.6A) 631  A 301 (-3.3A) 631  A 301 ( 4.5A) 631  A 301 ( 3.7A) 631  A 301 (-4.0A)	0.58A	21.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4k33	FIBROBLAST GROWTH FACTOR RECEPTOR 3 (Homo sapiens)	7 / 12	LEU A 478 VAL A 486 ALA A 506 LYS A 508 GLY A 561 LEU A 624 ASP A 635	ACP  A 801 (-3.8A) ACP  A 801 (-4.2A) ACP  A 801 (-3.3A) ACP  A 801 (-2.7A) ACP  A 801 ( 4.6A) ACP  A 801 (-4.4A) MG  A 802 ( 3.0A)	0.69A	36.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4mk0	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	8 / 12	VAL A 205 ALA A 218 LYS A 220 LEU A 271 GLY A 277 ASP A 278 LEU A 324 ASP A 335	29X  A 702 (-4.7A) 29X  A 702 (-3.1A) 29X  A 702 (-3.6A) 29X  A 702 ( 4.7A) None 29X  A 702 ( 4.8A) 29X  A 702 (-4.6A) 29X  A 702 (-4.4A)	1.01A	21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4mk0	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	7 / 12	VAL A 205 ALA A 218 LYS A 220 LEU A 271 LEU A 273 GLY A 276 LEU A 324	29X  A 702 (-4.7A) 29X  A 702 (-3.1A) 29X  A 702 (-3.6A) 29X  A 702 ( 4.7A) 29X  A 702 (-4.6A) None 29X  A 702 (-4.6A)	0.88A	21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	4mk0	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	7 / 12	VAL A 205 ALA A 218 LYS A 220 LEU A 271 LEU A 273 LEU A 324 ASP A 335	29X  A 702 (-4.7A) 29X  A 702 (-3.1A) 29X  A 702 (-3.6A) 29X  A 702 ( 4.7A) 29X  A 702 (-4.6A) 29X  A 702 (-4.6A) 29X  A 702 (-4.4A)	0.82A	21.55