POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	1d1t	ALCOHOL DEHYDROGENASE CLASS IV SIGMA CHAIN (Homo sapiens)	5 / 11	PHE A 176 ALA A 183 VAL A 184 SER A 177 GLY A 179	None	1.20A	21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	1nvp	TRANSCRIPTION INITIATION FACTOR IIA ALPHA CHAIN TRANSCRIPTION INITIATION FACTOR IIA BETA CHAIN TRANSCRIPTION INITIATION FACTOR IIA GAMMA CHAIN (Homo sapiens)	5 / 11	ASP C 364 ALA D  47 TYR B  14 GLY C 356 VAL D  52	None	1.08A	9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	1u3t	ALCOHOL DEHYDROGENASE ALPHA CHAIN (Homo sapiens)	5 / 11	PHE A 176 ALA A 183 VAL A 184 SER A 177 GLY A 179	None	1.24A	21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	2kt1	PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA (Homo sapiens)	5 / 11	PHE A  70 ASP A  69 VAL A  54 VAL A  75 GLY A  72	None	1.22A	10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	4nre	ARACHIDONATE 15-LIPOXYGENASE B (Homo sapiens)	5 / 11	PHE A 547 ASP A 459 ALA A 554 VAL A 556 GLY A 477	None None GOL  A 718 (-2.9A) None None	1.24A	23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	5epg	ALDEHYDE OXIDASE (Homo sapiens)	5 / 11	ASP A1093 VAL A1163 TYR A1161 SER A1265 GLY A1192	None	1.07A	17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	5fur	TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 (Homo sapiens)	5 / 11	ASP C 364 ALA D  47 TYR B  14 GLY C 356 VAL D  52	None	1.13A	6.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XNX_A_41XA707_1 (TRANSPORTER)	5i6z	SODIUM-DEPENDENT SEROTONIN TRANSPORTER (Homo sapiens)	8 / 11	ASP A  98 ALA A 169 TYR A 175 TYR A 176 GLY A 338 VAL A 343 SER A 438 GLY A 442	None	0.53A	53.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	5m4s	TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2,TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1,TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 (Homo sapiens)	5 / 11	ASP A 198 ALA A  47 VAL A 119 GLY A 190 VAL A  52	None	1.22A	10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	5 / 11	PHE A 371 VAL A 386 TYR A 382 VAL A 185 GLY A 380	None None GOL  A 506 ( 4.5A) None None	1.26A	11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	6eoq	DIPEPTIDYL PEPTIDASE 9 (Homo sapiens)	5 / 11	PHE A 734 VAL A 643 TYR A 644 GLY A 698 GLY A 733	None	1.02A	8.38