POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	1hfh	FACTOR H, 15TH AND 16TH C-MODULE PAIR (Homo sapiens)	4 / 8	HIS A  13 TYR A  34 ILE A  42 GLU A  12	None	1.36A	14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	1kq0	METHIONINE AMINOPEPTIDASE 2 (Homo sapiens)	4 / 8	TRP A 419 SER A 381 ILE A 194 GLU A 201	None	1.27A	19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	1l8k	T-CELL PROTEIN-TYROSINE PHOSPHATASE (Homo sapiens)	4 / 8	SER A 202 SER A 204 HIS A 209 ILE A 172	None	1.14A	21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	1rpm	RECEPTOR PROTEIN TYROSINE PHOSPHATASE MU (Homo sapiens)	4 / 8	SER A1084 SER A 993 ILE A1037 GLU A1052	None	1.19A	18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	1z8l	GLUTAMATE CARBOXYPEPTIDASE II (Homo sapiens)	4 / 8	SER A 483 SER A 496 TYR A 537 GLU A 486	None None None NAG  A1757 (-2.7A)	1.20A	20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	2adu	METHIONINE AMINOPEPTIDASE 2 (Homo sapiens)	4 / 8	TRP A 419 SER A 381 ILE A 194 GLU A 201	None	1.23A	22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	2edj	ROUNDABOUT HOMOLOG 2 (Homo sapiens)	4 / 8	SER A  85 SER A  83 ILE A  10 GLU A  87	None	1.22A	13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	2h31	MULTIFUNCTIONAL PROTEIN ADE2 (Homo sapiens)	4 / 8	SER A 400 SER A 179 HIS A 396 ILE A  64	None	1.29A	23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	2ooq	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE T (Homo sapiens)	4 / 8	SER A 945 SER A 949 HIS A 948 ILE A 970	None	1.16A	21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	2p3g	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 8	SER X 169 TYR X 194 ILE X 202 GLU X 165	None	1.36A	19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	2v55	RHO-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	4 / 8	SER A 263 SER A 242 ILE A 195 GLU A 258	None	1.32A	20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	3a5k	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 (Homo sapiens)	4 / 8	SER A 201 SER A 203 HIS A 208 ILE A 171	None	1.14A	21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	3thz	DNA MISMATCH REPAIR PROTEIN MSH2 (Homo sapiens)	4 / 8	SER A 738 SER A 734 ILE A 216 GLU A 731	None	1.25A	18.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	4mrm	GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1 (Homo sapiens)	5 / 8	TRP A  65 SER A 130 SER A 153 HIS A 170 GLU A 349	2BY  A 501 (-3.6A) 2BY  A 501 (-3.0A) 2BY  A 501 (-2.6A) 2BY  A 501 (-4.1A) 2BY  A 501 (-3.5A)	0.22A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	4q28	PERIPLAKIN (Homo sapiens)	4 / 8	SER A1652 HIS A1650 TYR A1738 GLU A1706	None	1.36A	14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	5gje	LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6 (Homo sapiens)	4 / 8	SER B1025 HIS B1205 TYR B1029 GLU B1067	None	1.12A	20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	5h1k	GEM-ASSOCIATED PROTEIN 5 (Homo sapiens)	4 / 8	SER A 200 HIS A 194 ILE A 253 TRP A 254	None	1.06A	20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	5nnz	DYNEIN ASSEMBLY FACTOR WITH WDR REPEAT DOMAINS 1 (Homo sapiens)	4 / 8	SER B 392 HIS B 386 ILE B 413 TRP B 414	None	1.33A	21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MS4_A_2C0A501_1 (GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1)	5nuv	AUTOPHAGY-RELATED PROTEIN 16-1 (Homo sapiens)	4 / 8	TRP A 435 SER A 390 HIS A 407 ILE A 455	None	1.11A	22.70