POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	2akz	GAMMA ENOLASE (Homo sapiens)	4 / 8	ARG A 402 ASP A 208 ALA A  38 SER A  39	None None PO4  A 442 (-3.5A) MG  A 441 (-2.1A)	1.01A	23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	2fv5	ADAM 17 (Homo sapiens)	4 / 8	ASP A 416 SER A 451 ALA A 413 SER A 457	None	0.98A	19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	2pz1	RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 (Homo sapiens)	4 / 8	ARG A 605 ASP A 525 SER A 498 ARG A 496	None	1.12A	20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	3a6p	EXPORTIN-5 (Homo sapiens)	4 / 8	PHE A 426 ASP A 425 SER A 364 SER A 369	None	1.17A	18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	3b97	ALPHA-ENOLASE (Homo sapiens)	4 / 8	ARG A 402 ASP A 208 ALA A  38 SER A  39	None None SO4  A 436 (-3.7A) MG  A 435 ( 2.3A)	1.01A	25.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	3h0t	FAB FRAGMENT, HEAVY CHAIN (Homo sapiens)	4 / 8	ARG B  70 ALA B  95 SER B  42 ARG B  45	None	0.83A	20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	3n00	NUCLEAR RECEPTOR COREPRESSOR 1 REV-ERBA-ALPHA (Homo sapiens)	4 / 8	PHE B2063 ARG B2065 ALA A 454 ARG A 461	None	1.17A	3.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	3toj	SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 (Homo sapiens)	4 / 8	ASP A 360 SER A 363 ALA A 355 TYR A 359	None	1.18A	17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	3w1g	DNA LIGASE 4 (Homo sapiens)	4 / 8	ARG A 278 ASP A 368 SER A 436 TYR A 438	ATP  A 701 (-4.3A) None None None	1.01A	21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	4x8n	SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 (Homo sapiens)	4 / 8	ASP A 360 SER A 363 ALA A 355 TYR A 359	None	1.15A	19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5jrp	MARBERG VIRUS MONOCLONAL ANTIBODY MR78 FAB HEAVY CHAIN (Homo sapiens)	4 / 8	ASP H 137 SER H 108 SER H  36 TYR H 110	None	1.03A	17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5lf7	PROTEASOME SUBUNIT BETA TYPE-1 (Homo sapiens)	4 / 8	ASP L 186 SER L 140 SER L  30 ARG L  28	None None None K  L 302 ( 4.6A)	0.95A	19.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5u2n	NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE (Homo sapiens)	7 / 8	PHE A 193 ARG A 196 ASP A 219 SER A 241 ALA A 244 SER A 275 ARG A 311	7TA  A 504 (-3.6A) SO4  A 501 ( 3.2A) 7TA  A 504 (-3.3A) 7TA  A 504 ( 3.8A) 7TA  A 504 (-3.5A) 7TA  A 504 (-2.7A) SO4  A 501 ( 3.2A)	0.24A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	1k1b	B-CELL LYMPHOMA 3-ENCODED PROTEIN (Homo sapiens)	4 / 7	HIS A 290 VAL A 250 ILE A 260 ALA A 292	None	0.87A	17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	1xfd	DIPEPTIDYL AMINOPEPTIDASE-LIKE PROTEIN 6 (Homo sapiens)	5 / 7	TYR A 515 VAL A 487 ILE A 463 ILE A 480 ALA A 517	None	1.39A	22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	3cqg	NUCLEAR PORE COMPLEX PROTEIN NUP107 (Homo sapiens)	4 / 7	HIS A 747 ILE A 723 ILE A 744 ALA A 743	None	0.87A	20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	3egi	TRIMETHYLGUANOSINE SYNTHASE HOMOLOG (Homo sapiens)	5 / 7	TYR A 803 VAL A 824 ILE A 826 ILE A 811 ALA A 809	None	1.48A	17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	1htr	GASTRICSIN PROGASTRICSIN (PRO SEGMENT) (Homo sapiens)	4 / 7	TYR B  14 ASP B 306 ALA B  13 SER P  12	None	1.21A	22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	1jmy	BILE-SALT-ACTIVATED LIPASE (Homo sapiens)	4 / 7	PHE A 324 ASP A 320 SER A 220 ALA A 436	None	0.92A	21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	1nug	PROTEIN-GLUTAMINE GLUTAMYLTRANSFERASE E (Homo sapiens)	4 / 7	SER A 195 ALA A 221 SER A 220 ARG A 217	None CA  A 703 (-4.5A) None None	1.22A	21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	2cqn	FORMIN-BINDING PROTEIN 3 (Homo sapiens)	4 / 7	ASP A 782 ALA A 749 SER A 748 ARG A 745	None	1.26A	8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	2fv5	ADAM 17 (Homo sapiens)	4 / 7	ASP A 416 SER A 451 ALA A 413 SER A 457	None	1.00A	19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	3a6p	EXPORTIN-5 (Homo sapiens)	4 / 7	PHE A 426 ASP A 425 SER A 364 SER A 369	None	1.21A	18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	3tje	FAB E09, HEAVY CHAIN (Homo sapiens)	4 / 7	TYR H  35 SER H  33 ALA H  54 SER H  63	None	1.24A	18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5fww	DICKKOPF-RELATED PROTEIN 1 KREMEN PROTEIN 1 (Homo sapiens)	4 / 7	ASP B 201 SER C 192 ALA C 202 ARG C 203	None	1.25A	20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5jrp	MARBERG VIRUS MONOCLONAL ANTIBODY MR78 FAB HEAVY CHAIN (Homo sapiens)	4 / 7	TYR H 110 ASP H 137 SER H 108 SER H  36	None	1.01A	17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5lf7	PROTEASOME SUBUNIT BETA TYPE-1 (Homo sapiens)	4 / 7	ASP L 186 SER L 140 SER L  30 ARG L  28	None None None K  L 302 ( 4.6A)	0.95A	19.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5u2n	NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE (Homo sapiens)	6 / 7	PHE A 193 ASP A 219 SER A 241 ALA A 244 SER A 275 ARG A 311	7TA  A 504 (-3.6A) 7TA  A 504 (-3.3A) 7TA  A 504 ( 3.8A) 7TA  A 504 (-3.5A) 7TA  A 504 (-2.7A) SO4  A 501 ( 3.2A)	0.23A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	6avo	PROTEASOME SUBUNIT BETA TYPE-8 (Homo sapiens)	4 / 7	ASP C 167 SER C 130 SER C  21 ARG C  19	None None BZ7  C 301 (-4.9A) None	1.24A	11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	6avo	PROTEASOME SUBUNIT BETA TYPE-9 (Homo sapiens)	4 / 7	ASP A 166 SER A 129 SER A  21 ARG A  19	None	1.23A	9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	1ex0	COAGULATION FACTOR XIII A CHAIN (Homo sapiens)	4 / 7	ILE A 612 ARG A 611 ILE A 549 ALA A 610	None	0.95A	20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	1zlr	COAGULATION FACTOR XI (Homo sapiens)	4 / 7	VAL A  59 ILE A  88 ILE A  90 ALA A 104	None	0.94A	20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	2jzx	POLY(RC)-BINDING PROTEIN 2 (Homo sapiens)	4 / 7	VAL A 159 ILE A  16 ILE A  68 ALA A  71	None	0.89A	16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	4cns	DIHYDROPYRIMIDINASE- LIKE 3 (Homo sapiens)	4 / 7	TYR A  32 VAL A  65 ILE A  35 ILE A  45	None	0.91A	21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	4ic7	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 (Homo sapiens)	4 / 7	VAL E  47 ILE E  21 ARG E  20 ILE E 104	None	0.94A	14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	4twe	N-ACETYLATED-ALPHA-L INKED ACIDIC DIPEPTIDASE-LIKE PROTEIN (Homo sapiens)	4 / 7	VAL A 448 ARG A  58 ILE A  57 ALA A  54	None	0.74A	22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5bx1	PROTEIN TYROSINE PHOSPHATASE TYPE IVA 1 (Homo sapiens)	4 / 7	TYR A  40 ILE A  63 ILE A  45 ALA A 101	None	0.94A	18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5m72	SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72 (Homo sapiens)	4 / 7	TYR A  86 ARG A  93 ILE A  94 ALA A  97	None	0.70A	14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5mr7	GRAINYHEAD-LIKE PROTEIN 2 HOMOLOG (Homo sapiens)	4 / 7	VAL A 300 ILE A 367 ILE A 344 ALA A 365	None	0.90A	9.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5u2n	NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE (Homo sapiens)	7 / 7	TYR A 188 HIS A 191 VAL A 242 ILE A 309 ARG A 349 ILE A 351 ALA A 379	None 7TA  A 504 (-3.6A) 7TA  A 504 (-4.3A) 7TA  A 504 (-4.4A) None 7TA  A 504 (-4.1A) 7TA  A 504 (-3.7A)	0.21A	100.00